1953-02-2 | 2-(2-sulfanylpropanamido)acetic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$7.00	$5.00
1g	98%	in stock	$9.00	$6.00
5g	98%	in stock	$13.00	$9.00
25g	98%	in stock	$39.00	$28.00
100g	98%	in stock	$138.00	$97.00

Description

• Catalog Number: AB47158
• Chemical Name: 2-(2-sulfanylpropanamido)acetic acid
• CAS Number: 1953-02-2
• Molecular Formula: C5H9NO3S
• Molecular Weight: 163.1949
• MDL Number: MFCD00004861
• SMILES: CC(C(=O)NCC(=O)O)S
• NSC Number: 760416

Computed Properties

• Complexity: 148
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 3
• Undefined Atom Stereocenter Count: 1
• XLogP3: -0.1

Literature

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• Effect of change in cellular GSH levels on mitochondrial damage and cell viability loss due to mitomycin c in small cell lung cancer cells.

  Biochemical pharmacology 20041101

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  Cardiovascular drugs and therapy 20041101

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  Yonsei medical journal 20041031

• Nanoparticles comprising a mixed monolayer for specific bindings with biomolecules.

  Journal of the American Chemical Society 20040929

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• The protective role of tiopronin in cisplatin ototoxicity in Wistar rats.

  International journal of audiology 20040901

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  The Journal of biological chemistry 20040813

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  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040805

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  Circulation 20040803

• Exogenous NO triggers preconditioning via a cGMP- and mitoKATP-dependent mechanism.

  American journal of physiology. Heart and circulatory physiology 20040801

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  Clinical rheumatology 20040801

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• Oligonucleotide-displaced organic monolayer-protected silver nanoparticles and enhanced luminescence of their salted aggregates.

  Analytical biochemistry 20040701

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  The Journal of biological chemistry 20040625

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  The Journal of pharmacology and experimental therapeutics 20040501

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  American journal of physiology. Heart and circulatory physiology 20040401

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  American journal of physiology. Heart and circulatory physiology 20040301

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  Anesthesiology 20040301

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  Basic research in cardiology 20040101

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  Chemistry (Weinheim an der Bergstrasse, Germany) 20031215

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  Anesthesia and analgesia 20031101

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  The Journal of clinical investigation 20031101

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• 3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin.

  The Biochemical journal 20030415

• Mitochondrial adenosine triphosphate-regulated potassium channel opening acts as a trigger for isoflurane-induced preconditioning by generating reactive oxygen species.

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  Chinese medical journal 20030101

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  Annals of nutrition & metabolism 20030101

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  Biochemical Society symposium 20030101

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  Anesthesiology 20021201

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  American journal of physiology. Heart and circulatory physiology 20020101

• Evaluation of genotoxic and cytotoxic potential of thiola (N-2-mercaptopropionylglycine), a medicine used in the treatment of humans contaminated with mercury.

  Environmental and molecular mutagenesis 20020101

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  Cell biology international 20020101

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  Experimental and clinical cardiology 20020101

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• Bucillamine prevents myocardial reperfusion injury.

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  American journal of physiology. Heart and circulatory physiology 20011201

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  The Journal of biological chemistry 20011012

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  The American journal of pathology 20011001

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  Basic research in cardiology 20010901

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• Menadione mimics the infarct-limiting effect of preconditioning in isolated rat hearts.

  American journal of physiology. Heart and circulatory physiology 20010801

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  Free radical biology & medicine 20010301

• Fluorescence quenching properties and chemiluminescence responses of alpha-ketothiols derivatized with o-phthalaldehyde and primary amino compounds.

  Luminescence : the journal of biological and chemical luminescence 20010101

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  Journal of veterinary internal medicine 20010101

• Prophylaxia of cystine calculosis by alpha-mercaptopropionyl-glycine administered continuously or every other day.

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• Nicotine exacerbates postischemic contractile dysfunction of 'stunned' myocardium in the canine model. Possible role of free radicals.

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• Pharmacokinetics of oral tiopronin.

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• The pharmacokinetics of tiopronin and its principal metabolite (2-mercaptopropionic acid) after oral administration to healthy volunteers.

  European journal of clinical pharmacology 19920101

• A case of nephrotic syndrome due to alpha-mercaptopropionyl glycine in a patient with familial cystinuria.

  Nihon Jinzo Gakkai shi 19900801

• Modulation of myoglobin-H2O2-mediated peroxidation reactions by sulfhydryl compounds.

  Laboratory investigation; a journal of technical methods and pathology 19881201

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  European journal of pharmacology 19871201

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• Toxicity due to remission inducing drugs in rheumatoid arthritis. Association with HLA-B35 and Cw4 antigens.

  The Journal of rheumatology 19860201

• Angiotensin-converting enzyme inhibitors potentiate the analgesic activity of [Met]-enkephalin-Arg6-Phe7 by inhibiting its degradation in mouse brain.

  Molecular pharmacology 19851201

• Thiorphan and analogs: lack of correlation between potency to inhibit 'enkephalinase A' in vitro and analgesic potency in vivo.

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