1001264-89-6 | GDC-0068

Packsize	Purity	Availability	Price	Discounted Price
5mg	98%	in stock	$56.00	$39.00
50mg	≥98%	in stock	$533.00	$373.00
100mg	≥98%	in stock	$798.00	$559.00

Description

• Catalog Number: AA01108
• Chemical Name: GDC-0068
• CAS Number: 1001264-89-6
• Molecular Formula: C24H32ClN5O2
• Molecular Weight: 457.9962
• MDL Number: MFCD22124514
• SMILES: CC(NC[C@@H](C(=O)N1CCN(CC1)c1ncnc2c1[C@H](C)C[C@H]2O)c1ccc(cc1)Cl)C

Computed Properties

• Complexity: 622
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 3
• Heavy Atom Count: 32
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 6
• XLogP3: 2.5

Literature

• Discovery and preclinical pharmacology of a selective ATP-competitive Akt inhibitor (GDC-0068) for the treatment of human tumors.

  Journal of medicinal chemistry 20120927