100299-08-9 | 4H-Pyrido[1,2-a]pyrimidin-4-one, 9-methyl-3-(2H-tetrazol-5-yl)-, potassium salt (1:1)

Packsize	Purity	Availability	Price	Discounted Price
10mg	98%	in stock	$7.00	$5.00
25mg	98%	in stock	$9.00	$6.00
50mg	98%	in stock	$15.00	$11.00
250mg	98%	in stock	$27.00	$19.00
1g	98%	in stock	$44.00	$31.00
5g	98%	in stock	$172.00	$120.00

Description

• Catalog Number: AA01719
• Chemical Name: 4H-Pyrido[1,2-a]pyrimidin-4-one, 9-methyl-3-(2H-tetrazol-5-yl)-, potassium salt (1:1)
• CAS Number: 100299-08-9
• Molecular Formula: C10H8KN6O
• Molecular Weight: 267.3084
• MDL Number: MFCD22575284
• SMILES: Cc1cccn2c1ncc(c2=O)c1n[nH]nn1.[K]

Computed Properties

• Complexity: 495
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1

Literature

• Pemirolast reduces cisplatin-induced kaolin intake in rats.

  European journal of pharmacology 20110701

• [Toxicity of topical ocular anti-allergic agents on human corneal epithelial cells in vitro].

  [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20100101

• Suppressive activity of pemirolast potassium, an antiallergic drug, on glomerulonephritis. Studies in glomerulonephritis model rats and in patients with chronic glomerulonephritis concurrently affected by allergic rhinitis.

  Arzneimittel-Forschung 20080101

• The effect of a combined therapy with a histamine H1 antagonist and a chemical mediator release inhibitor on allergic conjunctivitis.

  Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20080101

• A late cutaneous response in actively sensitized rats: a new method for evaluating the efficacy of antiallergic drugs.

  Journal of pharmacological sciences 20060801

• Prophylactic effect of pemirolast, an antiallergic agent, against hypersensitivity reactions to paclitaxel in patients with ovarian cancer.

  International journal of cancer 20060515

• Tetrazole compounds: the effect of structure and pH on Caco-2 cell permeability.

  Journal of pharmaceutical sciences 20060401

• Peripheral interstitial keratitis: a novel manifestation of ocular mastocytosis.

  Cornea 20060401

• Comparison of antigen-induced leukotriene and histamine release from nasal scrapings in allergic rhinitis.

  Rhinology 20050901

• Increasing effect by simultaneous use of levocabastine and pemirolast on experimental allergic conjunctivitis in rats.

  Biological & pharmaceutical bulletin 20050301

• Pemirolast potently attenuates paclitaxel hypersensitivity reactions through inhibition of the release of sensory neuropeptides in rats.

  Neuropharmacology 20040501

• A comparative trial of the safety and efficacy of 0.1 percent pemirolast potassium ophthalmic solution dosed twice or four times a day in patients with seasonal allergic conjunctivitis.

  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20040401

• Comparison of 0.1% bromfenac sodium and 0.1% pemirolast potassium for the treatment of allergic conjunctivitis.

  Japanese journal of ophthalmology 20040101

• Preventive effect of an antiallergic drug, pemirolast potassium, on restenosis after stent placement: quantitative coronary angiography and intravascular ultrasound studies.

  Journal of cardiology 20030701

• A combined analysis of two studies assessing the ocular comfort of antiallergy ophthalmic agents.

  Clinical therapeutics 20030401

• Two mast cell stabilizers, pemirolast potassium 0.1% and nedocromil sodium 2%, in the treatment of seasonal allergic conjunctivitis: a comparative study.

  Advances in therapy 20030101

• Pemirolast potassium 0.1% ophthalmic solution is an effective treatment for allergic conjunctivitis: a pooled analysis of two prospective, randomized, double-masked, placebo-controlled, phase III studies.

  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20021001

• Comparative effects of topical ocular anti-allergy drugs on human conjunctival mast cells.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 19971201

• A pilot study of pemirolast in patients with seasonal allergic rhinitis.

  Annals of allergy 19910201