100361-18-0 | 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$19.00	$13.00
5g	98%	in stock	$27.00	$19.00
25g	98%	in stock	$73.00	$51.00
100g	98%	in stock	$195.00	$136.00

Description

• Catalog Number: AA02033
• Chemical Name: 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
• CAS Number: 100361-18-0
• Molecular Formula: C12H8ClFN2O3
• Molecular Weight: 282.6549
• MDL Number: MFCD08458865
• SMILES: OC(=O)c1cn(C2CC2)c2c(c1=O)cc(c(n2)Cl)F

Computed Properties

• Complexity: 466
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 3.4

Upstream Synthesis Route

The compound 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid plays a crucial role in chemical synthesis as a versatile building block. It is commonly employed in the creation of pharmaceuticals, particularly antibacterial agents. This compound serves as a key intermediate in the synthesis of potent antimicrobial drugs, where its unique structure allows for important functional group modifications. By incorporating this compound into the synthesis pathway, chemists can efficiently access a variety of structurally diverse compounds with significant biological activities. The application of 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid in chemical synthesis showcases its importance in drug discovery and development processes.

Literature

• 4-Substituted 4-(1H-1,2,3-triazol-1-yl)piperidine: novel C7 moieties of fluoroquinolones as antibacterial agents.

  Bioorganic & medicinal chemistry letters 20100501

• The synthesis and biological evaluation of a novel series of C7 non-basic substituted fluoroquinolones as antibacterial agents.

  Bioorganic & medicinal chemistry letters 20090801