1004-38-2 | 2,4,6-Triaminopyrimidine

Packsize	Purity	Availability	Price	Discounted Price
5g	97%	in stock	$6.00	$4.00
10g	97%	in stock	$7.00	$5.00
25g	97%	in stock	$9.00	$6.00
100g	97%	in stock	$18.00	$13.00

Description

• Catalog Number: AA02282
• Chemical Name: 2,4,6-Triaminopyrimidine
• CAS Number: 1004-38-2
• Molecular Formula: C4H7N5
• Molecular Weight: 125.1319
• MDL Number: MFCD00006100
• SMILES: Nc1cc(N)nc(n1)N
• NSC Number: 26493

Computed Properties

• Complexity: 85
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 3
• XLogP3: -0.8

Literature

• Independence of net water flux from paracellular permeability in the intestine of Fundulus heteroclitus, a euryhaline teleost.

  The Journal of experimental biology 20120201

• Synthesis and biological evaluation of novel pyrimidine derivatives as sub-micromolar affinity ligands of GalR2.

  Bioorganic & medicinal chemistry letters 20111201

• Novel ligands for a purine riboswitch discovered by RNA-ligand docking.

  Chemistry & biology 20110325

• Structure-based design of pteridine reductase inhibitors targeting African sleeping sickness and the leishmaniases.

  Journal of medicinal chemistry 20100114

• Electrochemical behavior and voltammetric determination of 2,4,6-triaminopyrimidine at glassy carbon electrode modified with multi-walled carbon nanotubes/nafion.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20100101

• Novel non-classical C9-methyl-5-substituted-2,4-diaminopyrrolo[2,3-d]pyrimidines as potential inhibitors of dihydrofolate reductase and as anti-opportunistic agents.

  Bioorganic & medicinal chemistry 20061215

• Carbon protonation of 2,4,6-triaminopyrimidines: synthesis, NMR studies, and theoretical calculations.

  The Journal of organic chemistry 20060623

• Recyclable self-assembly-supported catalytic system for orthoalkylation.

  Organic letters 20050707

• Acute stress-induced hypersensitivity to colonic distension depends upon increase in paracellular permeability: role of myosin light chain kinase.

  Pain 20050101

• Structural variations of piritrexim, a lipophilic inhibitor of human dihydrofolate reductase: synthesis, antitumor activity and molecular modeling investigations.

  European journal of medicinal chemistry 20041201

• A new and efficient synthesis of pyrrolo[2,3-d]pyrimidine anticancer agents: Alimta (LY231514, MTA), homo-Alimta, TNP-351, and some aryl 5-substituted pyrrolo[2,3-d]pyrimidines.

  The Journal of organic chemistry 20031226

• In vivo sugar diffusion in the ileal epithelium of spontaneously hypertensive rats.

  Scandinavian journal of gastroenterology 20030901

• Proteinase-activated receptor-2-induced colonic inflammation in mice: possible involvement of afferent neurons, nitric oxide, and paracellular permeability.

  Journal of immunology (Baltimore, Md. : 1950) 20030415

• Gum arabic (GA) modifies paracellular water and electrolyte transport in the small intestine.

  Digestive diseases and sciences 20030401

• Protonation of the pyrimidine ring at the C(5) position: formation of a stable cationic sigma-complex.

  Journal of the American Chemical Society 20030305

• Non-classical antifolates, 5-(N-phenylpyrrolidin-3-yl)-2,4,6-triaminopyrimidines and 2,4-Diamino-6(5H)-oxopyrimidines, synthesis and antitumor studies.

  Bioorganic & medicinal chemistry 20030102

• Ionic balance in the freshwater-adapted Chinese crab, Eriocheir sinensis.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20010501

• Selective in vivo and in vitro effects of a small molecule inhibitor of cyclin-dependent kinase 4.

  Journal of the National Cancer Institute 20010321

• Fine structural specificity differences of trimethoprim allergenic determinants.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 19961001

• Purification and Characterization of an Inducible s-Triazine Hydrolase from Rhodococcus corallinus NRRL B-15444R.

  Applied and environmental microbiology 19940201