10090-05-8 | Silanol, 1,1,1-trimethyl-, 1-methanesulfonate

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	2 weeks	$23.00	$16.00
5g	95%	2 weeks	$34.00	$24.00
25g	95%	2 weeks	$85.00	$60.00
100g	95%	2 weeks	$285.00	$199.00

Description

• Catalog Number: AA03891
• Chemical Name: Silanol, 1,1,1-trimethyl-, 1-methanesulfonate
• CAS Number: 10090-05-8
• Molecular Formula: C4H12O3SSi
• Molecular Weight: 168.2868
• MDL Number: MFCD00042815
• SMILES: C[Si](OS(=O)(=O)C)(C)C

Upstream Synthesis Route

A versatile reagent in chemical synthesis, Trimethylsilyl methanesulfonate (TMS-MSA) is commonly employed in various reactions due to its ability to introduce the trimethylsilyl group onto functional groups. This transformation is particularly useful in protecting groups, where TMS-MSA can shield certain reactive sites within a molecular structure, allowing selective manipulation of specific functional groups without affecting the rest of the molecule. By forming stable silylethers through the silylation of alcohols, phenols, and carboxylic acids, TMS-MSA enables chemists to advance multi-step organic syntheses with precision and control. Additionally, TMS-MSA plays a crucial role in facilitating the generation of reactive intermediates and assisting in the formation of carbon-carbon and carbon-heteroatom bonds, thereby expanding the synthetic toolbox available to chemists in their efforts to construct complex molecules.