101214-22-6 | Fmoc-Glu(OtBu)-OSu

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$41.00	$29.00
5g	98%	in stock	$113.00	$79.00
25g	98%	in stock	$322.00	$225.00
100g	98%	in stock	$1,084.00	$759.00
500g	98%	in stock	$3,556.00	$2,490.00

Description

• Catalog Number: AE09671
• Chemical Name: Fmoc-Glu(OtBu)-OSu
• CAS Number: 101214-22-6
• Molecular Formula: C28H30N2O8
• Molecular Weight: 522.5464
• MDL Number: MFCD00235812
• SMILES: O=C(N[C@H](C(=O)ON1C(=O)CCC1=O)CCC(=O)OC(C)(C)C)OCC1c2ccccc2-c2c1cccc2

Upstream Synthesis Route

Fmoc-Glu(OtBu)-OSu is a widely used reagent in chemical synthesis, especially in the field of peptide and protein chemistry. This compound plays a crucial role as a key building block in the solid-phase peptide synthesis process. The Fmoc group acts as a temporary protecting group for the amino group, allowing for selective deprotection and subsequent coupling reactions. The glutamic acid residue (Glu) provides the peptide backbone with enhanced solubility and stability. The tert-butyl ester (OtBu) serves as a protecting group for the carboxylic acid, preventing unwanted side reactions during the synthesis process. The succinimide active ester (OSu) moiety facilitates efficient coupling reactions with amino groups on other amino acids.Overall, Fmoc-Glu(OtBu)-OSu enables precise and controlled peptide bond formation, making it an indispensable tool for chemists working on the synthesis of complex peptides and proteins with high purity and yield.