10124-65-9 | Potassium laurate

Packsize	Purity	Availability	Price	Discounted Price
1g	98%(HPLC)	in stock	$77.00	$54.00
5g	98%(HPLC)	in stock	$216.00	$151.00
25g	98%(HPLC)	in stock	$646.00	$452.00

Description

• Catalog Number: AA05026
• Chemical Name: Potassium laurate
• CAS Number: 10124-65-9
• Molecular Formula: C12H23KO2
• Molecular Weight: 238.4081
• MDL Number: MFCD00045925
• SMILES: CCCCCCCCCCCC(=O)[O-].[K+]

Computed Properties

• Complexity: 138
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 10

Literature

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• Dose-related effects of lauric acid on antropyloroduodenal motility, gastrointestinal hormone release, appetite, and energy intake in healthy men.

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  Lipids 20051001

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  Circulation 20050104

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• The interaction of azacrown ether with fatty acid in nonpolar solvents and at the organic-aqueous interface.

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  Langmuir : the ACS journal of surfaces and colloids 20040706

• Cholecystokinin pathways modulate sensations induced by gastric distension in humans.

  American journal of physiology. Gastrointestinal and liver physiology 20040701

• The effect of isoniazid on CYP2E1- and CYP4A-mediated hydroxylation of arachidonic acid in the rat liver and kidney.

  Drug metabolism and disposition: the biological fate of chemicals 20040701

• Effect of sodium laurate on ruminal fermentation and utilization of ruminal ammonia nitrogen for milk protein synthesis in dairy cows.

  Journal of dairy science 20040601

• Molecular analysis of peroxisome proliferation in the hamster.

  Toxicology and applied pharmacology 20040515

• Dynamical dimer structure and liquid structure of fatty acids in their binary liquid mixture: dodecanoic and 3-phenylpropionic acids system.

  Chemistry and physics of lipids 20040501

• Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1.

  The Journal of biological chemistry 20040423

• Phospholipids of Clostridium perfringens: a reexamination.

  FEMS microbiology letters 20040401

• Digestive and metabolic utilization of lauric, myristic and stearic acid in cows, and associated effects on milk fat quality.

  Archives of animal nutrition 20040401

• Production of poly(3-hydroxybutyrate- co-3-hydroxyhexanoate) with flexible 3-hydroxyhexanoate content in Aeromonas hydrophila CGMCC 0911.

  Applied microbiology and biotechnology 20040301

• A gas chromatography-mass spectrometry method for the measurement of fatty acid omega and omega(-1) hydroxylation kinetics by CYP4A1 using an artificial membrane system.

  Analytical biochemistry 20040215

• Smooth muscle--specific expression of CYP4A1 induces endothelial sprouting in renal arterial microvessels.

  Circulation research 20040206

• Solid-liquid phase behavior of binary fatty acid mixtures. 2. Mixtures of oleic acid with lauric acid, myristic acid, and palmitic acid.

  Chemistry and physics of lipids 20040201

• Enzymatic synthesis of monolaurin.

  Applied biochemistry and biotechnology 20040101

• Myristic acid increases delta6-desaturase activity in cultured rat hepatocytes.

  Reproduction, nutrition, development 20040101

• Effect of lauric acid on transdermal penetration of phenazepam in vivo.

  Bulletin of experimental biology and medicine 20031201

• [Synthesis of copolyesters consisting of 3-hydroxybutyrate and 3-hydroxyhexanoate by Aeromonas hydrophila WQ and its molecular basis].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20031201

• Synthesis and evaluation of amphiphilic RGD derivatives: uses for solvent casting in polymers and tissue engineering applications.

  Medical & biological engineering & computing 20031101

• [Fermentative production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) by recombinant Aeromonas hydrophila 4AK4 (pTG01)].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20031101

• Effects of fatty acids and iontophoresis on the delivery of midodrine hydrochloride and the structure of human skin.

  Pharmaceutical research 20031001

• Triacylglycerols determine the unusual storage physiology of Cuphea seed.

  Planta 20030901

• [Experimental provocation of panic attacks as a human experimental model for anxiety].

  Der Nervenarzt 20030901

• The reverse activity of human acid ceramidase.

  The Journal of biological chemistry 20030808

• A method for determining two substrates binding in the same active site of cytochrome P450BM3: an explanation of high energy omega product formation.

  Archives of biochemistry and biophysics 20030801

• Rabbit CYP4B1 engineered for high-level expression in Escherichia coli: ligand stabilization and processing of the N-terminus and heme prosthetic group.

  Archives of biochemistry and biophysics 20030801

• Interaction of polyhalogenated compounds of appropriate configuration with mammalian or bacterial CYP enzymes. Increased bilirubin and uroporphyrinogen oxidation in vitro.

  Biochemical pharmacology 20030801

• Activating omega-6 polyunsaturated fatty acids and inhibitory purine nucleotides are high affinity ligands for novel mitochondrial uncoupling proteins UCP2 and UCP3.

  The Journal of biological chemistry 20030606

• Effect of iontophoresis and fatty acids on permeation of arginine vasopressin through rat skin.

  Pharmacological research 20030601

• Safety and efficiency of modulating paracellular permeability to enhance airway epithelial gene transfer in vivo.

  Human gene therapy 20030520

• The effect of conjugated linoleic acid and medium-chain fatty acids on transepithelial calcium transport in human intestinal-like Caco-2 cells.

  The British journal of nutrition 20030501

• Covalent heme binding to CYP4B1 via Glu310 and a carbocation porphyrin intermediate.

  Biochemistry 20030422

• Combinatorial use of sodium laurate with taurine or L-glutamine enhances colonic absorption of rebamipide, poorly absorbable antiulcer drug, without any serious histopathological mucosal damages.

  Journal of pharmaceutical sciences 20030401

• Lipase-catalyzed synthesis of monoacylglycerol in a homogeneous system.

  Biotechnology letters 20030401

• Substitutional mutations in the uncoupling protein-specific sequences of mitochondrial uncoupling protein UCP1 lead to the reduction of fatty acid-induced H+ uniport.

  The international journal of biochemistry & cell biology 20030201

• Aromatic stacking as a determinant of the thermal stability of CYP119 from Sulfolobus solfataricus.

  Archives of biochemistry and biophysics 20030101

• Effects of mixtures of lauric and myristic acid on rumen methanogens and methanogenesis in vitro.

  Letters in applied microbiology 20030101

• Although it is rapidly metabolized in cultured rat hepatocytes, lauric acid is used for protein acylation.

  Reproduction, nutrition, development 20030101

• In vitro evaluation of the release of albuterol sulfate from polymer gels: effect of fatty acids on drug transport across biological membranes.

  Drug development and industrial pharmacy 20021101

• CYP119 plus a Sulfolobus tokodaii strain 7 ferredoxin and 2-oxoacid:ferredoxin oxidoreductase constitute a high-temperature cytochrome P450 catalytic system.

  Journal of the American Chemical Society 20021030

• Fatty acid augmentation of the cardiac slowly activating delayed rectifier current (IKs) is conferred by hminK.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001

• Methane emissions of differently fed dairy cows and corresponding methane and nitrogen emissions from their manure during storage.

  Environmental monitoring and assessment 20021001

• Human glutathione-dependent formaldehyde dehydrogenase. Structures of apo, binary, and inhibitory ternary complexes.

  Biochemistry 20020903

• CYP92B1, A cytochrome P450, expressed in petunia flower buds, that catalyzes monooxidation of long-chain fatty acids.

  Bioscience, biotechnology, and biochemistry 20020901

• Effect of dose of calcium salts of conjugated linoleic acid (CLA) on percentage and fatty acid content of milk fat in midlactation holstein cows.

  Journal of dairy science 20020801

• In-vitro release and transdermal fluxes of a highly lipophilic drug and of enhancers from matrix TDS.

  Journal of controlled release : official journal of the Controlled Release Society 20020718

• Suppressive effect of saturated acyl L-ascorbate on the oxidation of linoleic acid encapsulated with maltodextrin or gum arabic by spray-drying.

  Journal of agricultural and food chemistry 20020703

• Modulation of cytochrome P450 activity in the kidney of rats following long-term red wine exposure.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020701

• Full model for reversible kinetics of lipase-catalyzed sugar-ester synthesis in 2-methyl 2-butanol.

  Biotechnology and bioengineering 20020630

• Influence of glucose solubility and dissolution rate on the kinetics of lipase catalyzed synthesis of glucose laurate in 2-methyl 2-butanol.

  Biotechnology and bioengineering 20020630

• Lauric acid is desaturated to 12:1n-3 by hepatocytes and rat liver homogenates.

  Lipids 20020601

• [Study on the photofluorescence of Eu(III) and long chain fatty acid complexes].

  Guang pu xue yu guang pu fen xi = Guang pu 20020601

• Enhanced electron transfer and lauric acid hydroxylation by site-directed mutagenesis of CYP119.

  Journal of the American Chemical Society 20020522

• Effect of lauric acid and nisin-impregnated soy-based films on the growth of Listeria monocytogenes on turkey bologna.

  Poultry science 20020501

• Analysis methods of polysorbate 20: A new method to assess the stability of polysorbate 20 and established methods that may overlook degraded polysorbate 20.

  Pharmaceutical research 20020501

• Transdermal delivery of highly lipophilic drugs: in vitro fluxes of antiestrogens, permeation enhancers, and solvents from liquid formulations.

  Pharmaceutical research 20020501

• Cloning and expression of two novel pig liver and kidney fatty acid hydroxylases [cytochrome P450 (CYP)4A24 and CYP4A25].

  The Biochemical journal 20020415

• Mutations in erg4 affect the sensitivity of Saccharomyces cerevisiae to medium-chain fatty acids.

  Biochimica et biophysica acta 20020415

• Saturated triglycerides and fatty acids activate neutrophils depending on carbon chain-length.

  European journal of clinical investigation 20020401

• Quantification of lipopolysaccharides in outer membrane vesicle vaccines against meningococcal disease. High-performance liquid chromatographic determination of the constituent 3-hydroxy-lauric acid.

  Biologicals : journal of the International Association of Biological Standardization 20020301

• Semisolid SLN dispersions for topical application: influence of formulation and production parameters on viscoelastic properties.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20020301

• Mechanisms of cytoprotective effect of amino acids on local toxicity caused by sodium laurate, a drug absorption enhancer, in intestinal epithelium.

  Journal of pharmaceutical sciences 20020301

• Effects of cold exposure in vivo and uncouplers and recouplers in vitro on potato tuber mitochondria.

  Biochimica et biophysica acta 20020215

• Regio-specific hydroxylation of nonylphenol and the involvement of CYP2K- and CYP2M-like iso-enzymes in Atlantic salmon (Salmo salar).

  Aquatic toxicology (Amsterdam, Netherlands) 20020201

• Modulation of rat liver cytochrome P450 activity by prolonged red wine consumption.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020201

• Isolation and characterization of lipid in phloem sap of canola.

  Planta 20020201

• Fatty acid signalling in a mouse enteroendocrine cell line involves fatty acid aggregates rather than free fatty acids.

  The Journal of physiology 20020101

• Effect of dietary cholesterol, trans and saturated fatty acids on serum lipoproteins in non-human primates.

  Asia Pacific journal of clinical nutrition 20020101

• Ethanol- and nicotine-induced membrane changes in embryonic and neonatal chick brains.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20011001

• Industrial scale production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate).

  Applied microbiology and biotechnology 20011001

• Amino acids protect epithelial cells from local toxicity by absorption enhancer, sodium laurate.

  Journal of pharmaceutical sciences 20011001

• Killing of Gram-positive cocci by fatty acids and monoglycerides.

  APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20011001

• Nanoparticles of a polyelectrolyte-fatty acid complex: carriers for Q10 and triiodothyronine.

  Journal of controlled release : official journal of the Controlled Release Society 20010810

• Biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyvalerate-co-3-hydroxyhexanoate) by metabolically engineered Escherichia coli strains.

  Biotechnology and bioengineering 20010705

• Reconstitution of the enzymatic activities of cytochrome P450s using recombinant flavocytochromes containing rat cytochrome b(5) fused to NADPH--cytochrome P450 reductase with various membrane-binding segments.

  Archives of biochemistry and biophysics 20010615

• A transgenic mouse expressing human CYP4B1 in the liver.

  Biochemical and biophysical research communications 20010615

• Antimicrobial effects of corn zein films impregnated with nisin, lauric acid, and EDTA.

  Journal of food protection 20010601

• Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4.

  The Journal of biological chemistry 20010518

• Role of intrahelical arginine residues in functional properties of uncoupling protein (UCP1).

  Biochemistry 20010501

• Structural determinants of active site binding affinity and metabolism by cytochrome P450 BM-3.

  Archives of biochemistry and biophysics 20010301

• Raman spectroscopy in magnetic fluids.

  Biomolecular engineering 20010101

• Cholesterol-lowering effect of NK-104, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, in guinea pig model of hyperlipidemia.

  Arzneimittel-Forschung 20010101

• Bioadhesion of supramolecular structures at supported planar bilayers as studied by the quartz crystal microbalance.

  European biophysics journal : EBJ 20010101

• Effect of fatty acids on arenavirus replication: inhibition of virus production by lauric acid.

  Archives of virology 20010101

• Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) by metabolically engineered Escherichia coli strains.

  Biomacromolecules 20010101

• The R144C change in the CYP2C9*2 allele alters interaction of the cytochrome P450 with NADPH:cytochrome P450 oxidoreductase.

  Pharmacogenetics 19970601

• Induction, suppression and inhibition of multiple hepatic cytochrome P450 isozymes in the male rat and bobwhite quail (Colinus virginianus) by ergosterol biosynthesis inhibiting fungicides (EBIFs).

  Biochemical pharmacology 19941116

• Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids.

  Biochemistry 19930216

• Co-suppression by nicardipine, a calcium antagonist, of induction of microsomal lauric acid hydroxylation with peroxisome proliferation in clofibrate-treated rat liver.

  Chemical & pharmaceutical bulletin 19910501

• Effect of straight chain fatty acids on seizures induced by picrotoxin and pentylenetetrazole in mice.

  Journal of pharmacobio-dynamics 19900101