101530-10-3 | 1H-Imidazole-1-acetonitrile, α-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (αE)-

Packsize	Purity	Availability	Price	Discounted Price
5mg	98%(HPLC)	in stock	$77.00	$54.00
10mg	98%(HPLC)	in stock	$131.00	$92.00
25mg	98%(HPLC)	in stock	$246.00	$173.00
100mg	98%(HPLC)	in stock	$738.00	$517.00

Description

• Catalog Number: AA05936
• Chemical Name: 1H-Imidazole-1-acetonitrile, α-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (αE)-
• CAS Number: 101530-10-3
• Molecular Formula: C14H10ClN3S2
• Molecular Weight: 319.8323
• MDL Number: MFCD00865590
• SMILES: N#C/C(=C\1/SCC(S1)c1ccccc1Cl)/n1cncc1

Computed Properties

• Complexity: 445
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Undefined Atom Stereocenter Count: 1
• XLogP3: 3.3

Literature

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  Toxicological sciences : an official journal of the Society of Toxicology 20150601

• Comparison of the in vitro activity of terbinafine and lanoconazole against dermatophytes.

  Mycoses 20100701

• Efficacy of terbinafine compared to lanoconazole and luliconazole in the topical treatment of dermatophytosis in a guinea pig model.

  Medical mycology 20100501

• Triterpene alcohol and fatty acid composition of shea nuts from seven African countries.

  Journal of oleo science 20100101

• Separation and quantitation of Z-isomer in lanoconazole by normal phase HPLC.

  Journal of pharmaceutical and biomedical analysis 20091015

• Contact dermatitis due to lanoconazole, cetyl alcohol and diethyl sebacate in lanoconazole cream.

  Contact dermatitis 20040101

• A case of kerion celsi due to Arthroderma benhamiae identified by DNA sequences of nuclear ribosomal internal transcribed spacer 1 regions.

  Medical mycology 20030601

• In vitro activity of novel imidazole antifungal agent NND-502 against Malassezia species.

  International journal of antimicrobial agents 20030301

• Development of a new medium useful for the recovery of dermatophytes from clinical specimens by minimizing the carryover effect of antifungal agents.

  Microbiology and immunology 20020101

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  Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20020101

• A novel method using micropig stratum corneum in vitro for the evaluation of anti-Trichophyton mentagrophytes activity.

  Microbiology and immunology 20020101

• Synergy of lysozyme and lanoconazole on the morphology of Candida albicans.

  Journal of electron microscopy 20010101

• Usefulness of lanoconazole (Astat) cream in the treatment of hyperkeratotic type tinea pedis. Comparative study of monotherapy and combination therapy with 10% urea ointment (Pastaron).

  Mycoses 20010101

• Lanoconazole, a new imidazole antimycotic compound, protects MAIDS mice against encephalitis caused by Cryptococcus neoformans.

  The Journal of antimicrobial chemotherapy 20000901