101555-63-9 | Fmoc-d-pipecolic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	96%	in stock	$14.00	$10.00
5g	96%	in stock	$36.00	$26.00
100g	96%	in stock	$583.00	$408.00

Description

• Catalog Number: AA05976
• Chemical Name: Fmoc-d-pipecolic acid
• CAS Number: 101555-63-9
• Molecular Formula: C21H21NO4
• Molecular Weight: 351.3957
• MDL Number: MFCD00235899
• SMILES: OC(=O)[C@H]1CCCCN1C(=O)OCC1c2ccccc2-c2c1cccc2

Computed Properties

• Complexity: 514
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 26
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 4
• XLogP3: 3.7

Upstream Synthesis Route

The compound (2R)-1-[[(9H-Fluoren-9-yl)methoxy]carbonyl]piperidine-2-carboxylic acid, often referred to simply as $name$, serves as a versatile building block in chemical synthesis. With its unique structure combining a piperidine ring, a fluorenyl group, and a carboxylic acid functionality, this compound finds application in various synthetic pathways for the preparation of complex organic molecules.One key use of $name$ in chemical synthesis is as a chiral auxiliary or a chiral ligand. Its 2R configuration imparts chirality to the molecules it is incorporated into, allowing for the control and manipulation of stereochemistry during synthetic transformations. By leveraging the piperidine-2-carboxylic acid moiety for coordination with metal catalysts or as a directing group in reactions, chemists can selectively synthesize enantiomerically pure compounds, essential in the pharmaceutical and agrochemical industries.Furthermore, the fluorenyl-methoxy-carbonyl group attached to the piperidine ring offers protection to reactive functionalities during multi-step synthesis. This protective group can be selectively cleaved under mild conditions, allowing for strategic deprotection and unveiling of desired functional groups at specific stages of a synthetic route.Overall, the strategic placement and unique structural features of $name$ make it a valuable tool in organic synthesis, enabling chemists to access diverse chemical space and address the challenges of stereochemical control and functional group manipulation in complex molecule assembly.