101574-65-6 | Benzoic acid, 4-hydroxy-, 2-[[4-(1-methylethyl)phenyl]methylene]hydrazide

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$14.00	$10.00
5mg	95%	in stock	$50.00	$35.00
10mg	98%	in stock	$51.00	$36.00
25mg	98%	in stock	$84.00	$59.00
50mg	98%	in stock	$142.00	$100.00
100mg	98%	in stock	$240.00	$168.00
250mg	95%	in stock	$336.00	$235.00

Description

• Catalog Number: AA06050
• Chemical Name: Benzoic acid, 4-hydroxy-, 2-[[4-(1-methylethyl)phenyl]methylene]hydrazide
• CAS Number: 101574-65-6
• Molecular Formula: C17H18N2O2
• Molecular Weight: 282.3370
• MDL Number: MFCD00567155
• SMILES: Oc1ccc(cc1)C(=O)NN=Cc1ccc(cc1)C(C)C

Computed Properties

• Complexity: 352
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 21
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4
• XLogP3: 3.3

Literature

• Neurodevelopmental low-dose bisphenol A exposure leads to early life-stage hyperactivity and learning deficits in adult zebrafish.

  Toxicology 20120127

• Identification of pyrido[1,2-α]pyrimidine-4-ones as new molecules improving the transcriptional functions of estrogen-related receptor α.

  Journal of medicinal chemistry 20111110

• Estrogen-related receptor gamma is a key regulator of muscle mitochondrial activity and oxidative capacity.

  The Journal of biological chemistry 20100716

• An ERRbeta/gamma agonist modulates GRalpha expression, and glucocorticoid responsive gene expression in skeletal muscle cells.

  Molecular and cellular endocrinology 20100205

• Accessibility of the extracellular loops of follicle stimulating hormone receptor and their role in hormone-receptor interaction.

  Molecular and cellular endocrinology 20100205

• Efficient discovery of selective small molecule agonists of estrogen-related receptor gamma using combinatorial approach.

  Journal of combinatorial chemistry 20090101

• X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.

  The Journal of biological chemistry 20061208

• Identification and structure-activity relationship of phenolic acyl hydrazones as selective agonists for the estrogen-related orphan nuclear receptors ERRbeta and ERRgamma.

  Journal of medicinal chemistry 20050505