102-05-6 | Dibemethine

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$26.00	$18.00
1g	97%	in stock	$41.00	$29.00
5g	97%	in stock	$106.00	$75.00
10g	97%	in stock	$166.00	$116.00
25g	97%	in stock	$389.00	$272.00
100g	97%	in stock	$1,518.00	$1,062.00

Description

• Catalog Number: AA07872
• Chemical Name: Dibemethine
• CAS Number: 102-05-6
• Molecular Formula: C15H17N
• Molecular Weight: 211.30218000000005
• MDL Number: MFCD00022018
• SMILES: CN(Cc1ccccc1)Cc1ccccc1
• NSC Number: 163900

Computed Properties

• Complexity: 158
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 16
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• XLogP3: 3.5

Upstream Synthesis Route

Dibemethine, a versatile chemical compound, finds widespread application in chemical synthesis as a highly efficient reagent. With its unique properties, Dibemethine facilitates various key reactions in organic chemistry, making it a valuable asset in laboratory settings. Its potential use as a catalyst in asymmetric transformations has garnered significant interest among researchers, offering a powerful tool for constructing chiral molecules with high selectivity. Additionally, Dibemethine serves as a precursor for synthesizing complex organic compounds through its ability to participate in a range of reactions, including nucleophilic substitutions and cross-coupling processes. Its role in promoting efficient and sustainable chemical transformations underscores its importance in advancing synthetic methodologies and exploring new avenues in organic synthesis.

Literature

• A series of structurally simple chloroquine chemosensitizing dibemethin derivatives that inhibit chloroquine transport by PfCRT.

  European journal of medicinal chemistry 20110501

• Synthesis and cytotoxicity of novel 3-aryl-1-(3'-dibenzylaminomethyl-4'-hydroxyphenyl)-propenones and related compounds.

  Chemical & pharmaceutical bulletin 20081201

• Direct high-performance liquid chromatographic separation of the enantiomers of an aromatic amine and four aminoalcohols using polysaccharide chiral stationary phases and acidic additive.

  Chirality 20070801