10242-10-1 | 5-Chlorobenzofuran-2-carboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	96%	in stock	$16.00	$11.00
1g	96%	in stock	$32.00	$22.00
5g	96%	in stock	$105.00	$74.00
25g	96%	in stock	$386.00	$270.00

Description

• Catalog Number: AA09428
• Chemical Name: 5-Chlorobenzofuran-2-carboxylic acid
• CAS Number: 10242-10-1
• Molecular Formula: C9H5ClO3
• Molecular Weight: 196.5872
• MDL Number: MFCD00060512
• SMILES: Clc1ccc2c(c1)cc(o2)C(=O)O

Computed Properties

• Complexity: 219
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 3

Upstream Synthesis Route

5-Chlorobenzofuran-2-carboxylic acid is a versatile compound widely used in chemical synthesis as a key building block for the production of various pharmaceuticals, agrochemicals, and materials. In organic chemistry, it serves as an important intermediate in the synthesis of biologically active compounds due to its unique structure and reactivity.This compound can be utilized for the development of novel drugs, such as antiviral agents, anti-inflammatory drugs, and anti-cancer therapies. Its presence in the chemical structure of these pharmaceuticals imparts specific biological activities, making it a valuable component in drug discovery and development.Additionally, 5-Chlorobenzofuran-2-carboxylic acid is employed in the synthesis of specialized materials, including liquid crystals, dyes, and polymers. Its ability to undergo various chemical transformations, such as esterification, amidation, and halogenation, allows for the modification of its properties to suit different applications in material science.Overall, the application of 5-Chlorobenzofuran-2-carboxylic acid in chemical synthesis showcases its significance in the creation of diverse compounds with potential therapeutic and material-related benefits.

Literature

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Non-peptidic small-molecule inhibitors of the single-chain hepatitis C virus NS3 protease/NS4A cofactor complex discovered by structure-based NMR screening.

  Journal of medicinal chemistry 20040506