1026796-35-9 | 3-Ethoxy-4-(trifluoromethyl)phenylboronic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$330.00	$231.00
5g	98%	in stock	$945.00	$661.00
10g	98%	in stock	$1,504.00	$1,053.00

Description

• Catalog Number: AA10288
• Chemical Name: 3-Ethoxy-4-(trifluoromethyl)phenylboronic acid
• CAS Number: 1026796-35-9
• Molecular Formula: C9H10BF3O3
• Molecular Weight: 233.98010959999996
• MDL Number: MFCD21609514
• SMILES: CCOc1cc(ccc1C(F)(F)F)B(O)O

Upstream Synthesis Route

3-Ethoxy-4-(trifluoromethyl)phenylboronic acid is a versatile compound that plays a crucial role in chemical synthesis, specifically in the field of organic chemistry. This compound is commonly used as a boronic acid building block in the synthesis of various complex organic molecules. Its unique structure, characterized by the presence of an ethoxy group and a trifluoromethyl group attached to a phenylboronic acid core, enables it to participate in diverse chemical reactions.One of the primary applications of 3-Ethoxy-4-(trifluoromethyl)phenylboronic acid is in Suzuki-Miyaura cross-coupling reactions. In this reaction, the boronic acid functionality facilitates the coupling of the phenyl group with various electrophiles under mild conditions, leading to the formation of biaryl compounds. This method is widely employed in the pharmaceutical industry and academia for the synthesis of drug candidates, agrochemicals, and materials science.Furthermore, this compound can also be utilized in transition metal-catalyzed C-H activation reactions, where the trifluoromethyl group enhances the reactivity and selectivity of the boronic acid, enabling the functionalization of aromatic and heteroaromatic compounds. This strategy allows for the direct introduction of diverse functional groups onto complex molecular scaffolds, expanding the synthetic toolbox available to chemists.Overall, 3-Ethoxy-4-(trifluoromethyl)phenylboronic acid is a valuable reagent in chemical synthesis, enabling the construction of complex organic molecules through versatile and efficient synthetic methodologies. Its unique structural features and reactivity make it an indispensable tool for researchers and synthetic chemists in the pursuit of novel compounds with potential applications in medicine, materials science, and beyond.