102692-35-3 | 4,4'-Difluorochalcone

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$40.00	$28.00
1g	95%	in stock	$57.00	$40.00
5g	95%	in stock	$177.00	$124.00
10g	95%	in stock	$297.00	$208.00
25g	95%	in stock	$572.00	$400.00

Description

• Catalog Number: AE08181
• Chemical Name: 4,4'-Difluorochalcone
• CAS Number: 102692-35-3
• Molecular Formula: C15H10F2O
• Molecular Weight: 244.2361
• MDL Number: MFCD00219906
• SMILES: Fc1ccc(cc1)C=CC(=O)c1ccc(cc1)F
• NSC Number: 54889

Computed Properties

• Complexity: 298
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• XLogP3: 3.3

Upstream Synthesis Route

4,4'-DICHLOROCHALCONE is a versatile compound that finds wide application in chemical synthesis. It serves as a key building block in the creation of various pharmaceuticals, agrochemicals, and materials, owing to its unique reactivity and structural properties. In chemical synthesis, 4,4'-DICHLOROCHALCONE is often used as a precursor for the synthesis of complex organic molecules via nucleophilic substitution reactions. Its specific substitution pattern and electron density make it particularly valuable in the formation of new carbon-carbon and carbon-heteroatom bonds. Additionally, 4,4'-DICHLOROCHALCONE can act as a scaffold for introducing functional groups or modifying existing chemical structures, enabling the creation of diverse molecular architectures with tailored properties. This compound's role in chemical synthesis highlights its importance in the production of fine chemicals and advanced materials for various industrial applications.

Literature

• Combretastatin-like chalcones as inhibitors of microtubule polymerization. Part 1: synthesis and biological evaluation of antivascular activity.

  Bioorganic & medicinal chemistry 20091115

• Discovery of novel heteroaryl-substituted chalcones as inhibitors of TNF-alpha-induced VCAM-1 expression.

  Bioorganic & medicinal chemistry letters 20040322