1027642-25-6 | Potassium benzyloxymethyltrifluoroborate

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$26.00	$19.00
5g	98%	in stock	$89.00	$63.00
10g	98%	in stock	$177.00	$124.00
25g	98%	in stock	$354.00	$248.00

Description

• Catalog Number: AA10581
• Chemical Name: Potassium benzyloxymethyltrifluoroborate
• CAS Number: 1027642-25-6
• Molecular Formula: C8H9BF3KO
• Molecular Weight: 228.061
• MDL Number: MFCD11052815
• SMILES: F[B-](COCc1ccccc1)(F)F.[K+]

Computed Properties

• Complexity: 148
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3

Upstream Synthesis Route

Potassium ((benzyloxy)methyl)trifluoroborate is a versatile reagent commonly utilized in organic synthesis. Its unique structure combines the reactivity of a boronate ester with the stability and solubility provided by the potassium counterion. This compound serves as a valuable building block in the construction of complex molecules due to its ability to undergo diverse transformations under mild conditions.One of the key applications of Potassium ((benzyloxy)methyl)trifluoroborate is in cross-coupling reactions, particularly in Suzuki-Miyaura coupling. In this transformative process, the boron moiety of the reagent reacts with an aryl or vinyl halide in the presence of a palladium catalyst to form a new carbon-carbon bond. This methodology enables chemists to access a wide array of biaryl and polyarylether compounds, which are prevalent in pharmaceuticals, agrochemicals, and materials science.Additionally, Potassium ((benzyloxy)methyl)trifluoroborate can participate in other important reactions such as Buchwald-Hartwig amination, Heck reaction, and Sonogashira coupling. These diverse reactivity profiles make it a valuable tool for the construction of complex molecular frameworks in a controlled and efficient manner.Overall, the application of Potassium ((benzyloxy)methyl)trifluoroborate in chemical synthesis highlights its significance as a key reagent for the advancement of modern organic chemistry.