102767-28-2 | (2S)-2-(2-oxopyrrolidin-1-yl)butanamide

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$6.00	$4.00
1g	98%	in stock	$12.00	$9.00
5g	98%	in stock	$15.00	$11.00
10g	98%	in stock	$24.00	$17.00
25g	98%	in stock	$44.00	$31.00
100g	98%	in stock	$141.00	$99.00
500g	98%	in stock	$573.00	$402.00

Description

• Catalog Number: AA10591
• Chemical Name: (2S)-2-(2-oxopyrrolidin-1-yl)butanamide
• CAS Number: 102767-28-2
• Molecular Formula: C8H14N2O2
• Molecular Weight: 170.2090
• MDL Number: MFCD03265610
• SMILES: CC[C@H](N1CCCC1=O)C(=O)N
• NSC Number: 760119

Computed Properties

• Complexity: 203
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3
• XLogP3: -0.3

Literature

• Antiepileptic drugs: Impacts on human serum paraoxonase-1.

  Journal of biochemical and molecular toxicology 20170601

• Brivaracetam, a selective high-affinity synaptic vesicle protein 2A (SV2A) ligand with preclinical evidence of high brain permeability and fast onset of action.

  Epilepsia 20160201

• Efficacy and safety of ezogabine/retigabine as adjunctive therapy to specified single antiepileptic medications in an open-label study of adults with partial-onset seizures.

  Seizure 20150801

• Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.

  Chemical research in toxicology 20150518

• Zebrafish embryotoxicity test for developmental (neuro)toxicity: Demo case of an integrated screening approach system using anti-epileptic drugs.

  Reproductive toxicology (Elmsford, N.Y.) 20141101

• Seizure control in Unverricht-Lundborg disease: a single-centre study.

  Epileptic disorders : international epilepsy journal with videotape 20140601

• Valproic acid, but not levetiracetam, selectively decreases HDAC7 and HDAC2 expression in human ovarian cancer cells.

  Toxicology letters 20140113

• Valproate-related erythrodermia with reversible encephalopathy: a rare but serious adverse reaction, case report.

  Acta dermatovenerologica Alpina, Pannonica, et Adriatica 20140101

• Two medical therapies very effective shortly after high levels of soman poisoning in rats, but only one with universal utility.

  Toxicology 20131215

• A lamotrigine induced toxic epidermal necrolysis in a child.

  Cutaneous and ocular toxicology 20130301

• Levetiracetam-associated aggravation of myoclonic seizure in children.

  Seizure 20121201

• Stevens-Johnson syndrome induced by levetiracetam.

  Seizure 20121201

• Prevalence, utilization, and costs of antiepileptic drugs for epilepsy in Germany--a nationwide population-based study in children and adults.

  Journal of neurology 20121101

• Solid-liquid phase diagrams for the determination of the solid state nature of both polymorphs of (RS)-2-(2-oxo-pyrrolidin-1-yl)-butyramide.

  International journal of pharmaceutics 20121101

• Levetiracetam for busulfan-induced seizure prophylaxis in children undergoing hematopoietic stem cell transplantation.

  Pediatric blood & cancer 20121001

• Spectroscopic studies on the interaction of calf thymus DNA with the drug levetiracetam.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121001

• [Clinical efficacy of the novel antiepileptic agent levetiracetam: evaluation in patients with localization-related epilepsy].

  Brain and nerve = Shinkei kenkyu no shinpo 20121001

• Levetiracetam add-on for drug-resistant focal epilepsy: an updated Cochrane Review.

  The Cochrane database of systematic reviews 20120912

• Rare protein sequence variation in SV2A gene does not affect response to levetiracetam.

  Epilepsy research 20120901

• Increased levetiracetam clearance in pregnancy: is seizure frequency affected?

  Seizure 20120901

• Anti-inflammatory effects of levetiracetam in experimental autoimmune encephalomyelitis.

  International immunopharmacology 20120901

• Intravenous levetiracetam in acute repetitive seizures and status epilepticus in children: experience from a children's hospital.

  Seizure 20120901

• Acquired epileptiform opercular syndrome: F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) findings and efficacy of levetiracetam therapy.

  Epilepsy & behavior : E&B 20120901

• A case of amiodarone-associated myoclonus responsive to levetiracetam.

  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20120901

• [Latest news on the anti-alzheimer's front].

  Revue medicale suisse 20120829

• A rat model for LGI1-related epilepsies.

  Human molecular genetics 20120815

• [Juvenile myoclonic epilepsy].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20120807

• A double-blind, placebo-controlled trial assessing the efficacy of levetiracetam extended-release in very heavy drinking alcohol-dependent patients.

  Alcoholism, clinical and experimental research 20120801

• Levetiracetam extended release conversion to monotherapy for the treatment of patients with partial-onset seizures: a double-blind, randomised, multicentre, historical control study.

  Epilepsy research 20120801

• The synaptic vesicle glycoprotein 2A ligand levetiracetam inhibits presynaptic Ca2+ channels through an intracellular pathway.

  Molecular pharmacology 20120801

• Practice variations in the management of status epilepticus.

  Neurocritical care 20120801

• Synthesis and anticonvulsant activity of new N-Mannich bases derived from 3-(2-fluorophenyl)- and 3-(2-bromophenyl)-pyrrolidine-2,5-diones. Part II.

  Bioorganic & medicinal chemistry 20120801

• Results of phase II pharmacokinetic study of levetiracetam for prevention of post-traumatic epilepsy.

  Epilepsy & behavior : E&B 20120801

• Pharmacokinetic variability of four newer antiepileptic drugs, lamotrigine, levetiracetam, oxcarbazepine, and topiramate: a comparison of the impact of age and comedication.

  Therapeutic drug monitoring 20120801

• Levetiracetam in the treatment of alcohol dependence: toward the end of the story?

  Alcoholism, clinical and experimental research 20120801

• Leukoencephalopathy, cerebral calcifications, and cysts: case report.

  Clinical neurology and neurosurgery 20120701

• A randomized, placebo-controlled trial of levetiracetam in central pain in multiple sclerosis.

  European journal of pain (London, England) 20120701

• A seven-day study of the pharmacokinetics of intravenous levetiracetam in neonates: marked changes in pharmacokinetics occur during the first week of life.

  Pediatric research 20120701

• Phenytoin reduces 5-aminolevulinic acid-induced protoporphyrin IX accumulation in malignant glioma cells.

  Journal of neuro-oncology 20120701

• Bone mineral density in adult patients treated with various antiepileptic drugs.

  Seizure 20120701

• Effects of Levetiracetam on neural tube development and closure of the chick embryos in ovo.

  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20120701

• The acute effects of levetiracetam on nocturnal sleep and daytime sleepiness in patients with partial epilepsy.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20120701

• Postmortem levetiracetam (Keppra®) data from North Carolina.

  Journal of analytical toxicology 20120701

• Quieting the overactive hippocampus restores memory in aging.

  Trends in cognitive sciences 20120701

• Levetiracetam-induced reversible autistic regression.

  Pediatric neurology 20120701

• Levetiracetam inhibits neurotransmitter release associated with CICR.

  Neuroscience letters 20120619

• A systematic review of randomized controlled trials on the theraputic effect of intravenous sodium valproate in status epilepticus.

  The International journal of neuroscience 20120601

• Levetiracetam may favorably affect seizure outcome after temporal lobectomy.

  Epilepsia 20120601

• Modulation of action potential and calcium signaling by levetiracetam in rat sensory neurons.

  Journal of receptor and signal transduction research 20120601

• Assessing adherence-based quality measures in epilepsy.

  International journal for quality in health care : journal of the International Society for Quality in Health Care 20120601

• Levetiracetam induced angioedema in a patient with previous anticonvulsant hypersensitivity reaction to phenytoin and lamotrigine.

  Seizure 20120601

• Levetiracetam-associated loss of libido and anhedonia.

  Epilepsy & behavior : E&B 20120601

• Gaucher disease: successful treatment of myoclonic status epilepticus with levetiracetam.

  Epileptic disorders : international epilepsy journal with videotape 20120601

• Population pharmacokinetics modeling of levetiracetam in Chinese children with epilepsy.

  Acta pharmacologica Sinica 20120601

• Reduction of hippocampal hyperactivity improves cognition in amnestic mild cognitive impairment.

  Neuron 20120510

• An acquired source of seizures.

  BMJ (Clinical research ed.) 20120503

• Amelioration of disabling myoclonus in a case of DRPLA by levetiracetam.

  Brain & development 20120501

• Effect of levetiracetam monotherapy on background EEG activity and cognition in drug-naïve epilepsy patients.

  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20120501

• Levetiracetam as alternative stage two antiepileptic drug in status epilepticus: a systematic review.

  Seizure 20120501

• [Two cases of autoimmune encephalitis with antibodies to N-methyl-D-aspartate receptor in intensive care].

  Annales francaises d'anesthesie et de reanimation 20120501

• The effect of levetiracetam on focal nocturnal epileptiform activity during sleep--a placebo-controlled double-blind cross-over study.

  Epilepsy & behavior : E&B 20120501

• [Therapeutic effects of levetiracetam on electrical status epilepticus during sleep in children].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20120501

• [Keppra in pregnancy. Generally lower risk of birth defects in monotherapy].

  Lakartidningen 20120501

• Pilomotor seizure: when paroxysmal gooseflesh heralds brain tumor.

  Neurology 20120410

• Levetiracetam versus lorazepam in status epilepticus: a randomized, open labeled pilot study.

  Journal of neurology 20120401

• Management of acute seizure and status epilepticus in pediatric emergency.

  Indian journal of pediatrics 20120401

• The anticonvulsant levetiracetam potentiates alcohol consumption in non-treatment seeking alcohol abusers.

  Journal of clinical psychopharmacology 20120401

• New observations in primary and secondary reading epilepsy: excellent response to levetiracetam and early spontaneous remission.

  Epilepsy & behavior : E&B 20120401

• Pancytopenia associated with levetiracetam treatment in Lafora's disease.

  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20120301

• Levetiracetam has an activity-dependent effect on inhibitory transmission.

  Epilepsia 20120301

• Determination of ng/mL levetiracetam using ultra-high-performance liquid chromatography-photodiode absorbance.

  Journal of chromatographic science 20120301

• Initial EEG predicts outcomes in a trial of levetiracetam vs. fosphenytoin for seizure prevention.

  Epilepsy & behavior : E&B 20120301

• Recurrent seizures in a levetiracetam-treated patient after subarachnoid hemorrhage: a matter of enhanced renal function?

  Epilepsy & behavior : E&B 20120301

• [Effect of levetiracetam on intractable secondarily generalized seizure and depression].

  Brain and nerve = Shinkei kenkyu no shinpo 20120301

• Performance characteristics and patient comparison of the ARK Diagnostics levetiracetam immunoassay with an ultra-high performance liquid chromatography with tandem mass spectrometry detection method.

  Clinica chimica acta; international journal of clinical chemistry 20120218

• Phenytoin, levetiracetam, and pregabalin in the acute management of refractory status epilepticus in patients with brain tumors.

  Neurocritical care 20120201

• Intravenous and oral levetiracetam in patients with a suspected primary brain tumor and symptomatic seizures undergoing neurosurgery: the HELLO trial.

  Acta neurochirurgica 20120201

• Levetiracetam clinical pharmacokinetics in elderly and very elderly patients with epilepsy.

  Epilepsy research 20120201

• Interactions of pregabalin with gabapentin, levetiracetam, tiagabine and vigabatrin in the mouse maximal electroshock-induced seizure model: a type II isobolographic analysis.

  Epilepsy research 20120201

• Synthesis and anticonvulsant activity of novel 2,6-diketopiperazine derivatives. Part 2: Perhydropyrido[1,2-a]pyrazines.

  European journal of medicinal chemistry 20120201

• Sensitivity of computed tomography angiography vs catheter angiography in the detection of a ruptured intracranial infectious aneurysm in a pregnant woman.

  Archives of neurology 20120201

• Bioequivalence of a novel minitablet formulation of levetiracetam.

  Arzneimittel-Forschung 20120201

• Positive impact of levetiracetam on emotional learning and memory in naive mice.

  Life sciences 20120130

• Ventricular fibrillation in loop recorder memories in a patient with early repolarization syndrome.

  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20120101

• A long-term open-label extension study assessing cognition and behavior, tolerability, safety, and efficacy of adjunctive levetiracetam in children aged 4 to 16 years with partial-onset seizures.

  Journal of child neurology 20120101

• Adjunctive levetiracetam in children, adolescents, and adults with primary generalized seizures: open-label, noncomparative, multicenter, long-term follow-up study.

  Epilepsia 20120101

• Treatment with levetiracetam in a patient with pervasive developmental disorders, severe intellectual disability, self-injurious behavior, and seizures: a case report.

  Neurocase 20120101

• Levetiracetam-induced interstitial nephritis in a patient with glioma.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20120101

• Teratogenicity of the newer antiepileptic drugs--the Australian experience.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20120101

• Levetiracetam compared to phenytoin for the prevention of postoperative seizures after craniotomy for intracranial tumours in patients without epilepsy.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20120101

• [Experience with levetiracetam in the treatment of childhood refractory epilepsy].

  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20120101

• Choice of antiepileptic drugs for the elderly: possible drug interactions and adverse effects.

  Expert opinion on drug metabolism & toxicology 20120101

• A case of physical and mental adverse drug reactions associated with levetiracetam in post-stroke epilepsy.

  Journal of the American Geriatrics Society 20120101

• Evaluation of levetiracetam as adjunctive treatment for refractory canine epilepsy: a randomized, placebo-controlled, crossover trial.

  Journal of veterinary internal medicine 20120101

• Double-masked, placebo-controlled study of intravenous levetiracetam for the treatment of status epilepticus and acute repetitive seizures in dogs.

  Journal of veterinary internal medicine 20120101

• A cost-minimization analysis of phenytoin versus levetiracetam for early seizure pharmacoprophylaxis after traumatic brain injury.

  The journal of trauma and acute care surgery 20120101

• Levetiracetam and psychosis.

  Actas espanolas de psiquiatria 20120101

• Effects of valproic acid and levetiracetam on viability and cell cycle regulatory genes expression in the OVCAR-3 cell line.

  Pharmacological reports : PR 20120101

• An initial experience with therapeutic drug monitoring of levetiracetam as reported from a pediatric clinical setting in India.

  Neurology India 20120101

• Phenytoin versus Leviteracetam for seizure prophylaxis after brain injury - a meta analysis.

  BMC neurology 20120101

• Levetiracetam-induced drug reaction with eosinophilia and systemic symptoms syndrome.

  The Annals of pharmacotherapy 20120101

• Levetiracetam may worsen myoclonus in patients with juvenile myoclonic epilepsy: case reports.

  Clinical neuropharmacology 20120101

• Comparison of the effects of valproic acid and levetiracetam on apoptosis in the human ovarian cancer cell line OVCAR-3.

  Pharmacological reports : PR 20120101

• Presentation of opsoclonus myoclonus ataxia syndrome with glutamic acid decarboxylase antibodies.

  BMJ case reports 20120101

• [Complex therapy of idiopathic forms of epilepsy with small doses of valproates and levetiracetam].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20120101

• [The results of the use of levetiracetam (keppra) in post-stroke epilepsy].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20120101

• [Idiopathic generalized epilepsy in young women: choise of treatment strategy].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20120101

• Development and validation of an analytical method based on high performance thin layer chromatography for the simultaneous determination of lamotrigine, zonisamide and levetiracetam in human plasma.

  Journal of pharmaceutical and biomedical analysis 20111205

• Enhanced efficacy of anticonvulsants when combined with levetiracetam in soman-exposed rats.

  Neurotoxicology 20111201

• [Treating Neonates with Levetiracetam: a survey among German University Hospitals].

  Klinische Padiatrie 20111201

• Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

  PLoS computational biology 20111201

• Optimized and validated flow-injection spectrophotometric analysis of topiramate, piracetam and levetiracetam in pharmaceutical formulations.

  Acta pharmaceutica (Zagreb, Croatia) 20111201

• Seizures as a manifestation of multiple sclerosis.

  Epileptic disorders : international epilepsy journal with videotape 20111201

• Early-onset childhood absence epilepsy: is it a distinct entity?

  Epileptic disorders : international epilepsy journal with videotape 20111201

• Modulation of abnormal synaptic transmission in hippocampal CA3 neurons of spontaneously epileptic rats (SERs) by levetiracetam.

  Brain research bulletin 20111125

• Aggravation of absence seizure related to levetiracetam.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20111101

• Levetiracetam reduces the frequency of interictal epileptiform discharges during NREM sleep in children with ADHD.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20111101

• Study on the absolute configuration of levetiracetam via density functional theory calculations of electronic circular dichroism and optical rotatory dispersion.

  Journal of pharmaceutical and biomedical analysis 20111101

• Off-label gabapentin masking ictal triphasic waves: case analysis of neuropsychiatric and electrographic correlates.

  Epilepsy & behavior : E&B 20111101

• Levetiracetam in primary orthostatic tremor: a double-blind placebo-controlled crossover study.

  Movement disorders : official journal of the Movement Disorder Society 20111101

• Self-reported symptoms in patients on antiepileptic drugs in monotherapy.

  Acta neurologica Scandinavica 20111101

• Epileptic seizures after octreotide administration in a 6.5-year-old female with ALL and L-asparaginase associated pancreatitis: a possible drug interaction.

  Klinische Padiatrie 20111101

• Synthesis and anticonvulsant activity of new N-Mannich bases derived from 5-cyclopropyl-5-phenyl- and 5-cyclopropyl-5-(4-chlorophenyl)-imidazolidine-2,4-diones.

  Bioorganic & medicinal chemistry 20111015

• Abnormal facilitatory mechanisms in motor cortex of migraine with aura.

  European journal of pain (London, England) 20111001

• Levetiracetam compared to valproic acid: plasma concentration levels, adverse effects and interactions in aneurysmal subarachnoid hemorrhage.

  Clinical neurology and neurosurgery 20111001

• A prospective study of levetiracetam efficacy in epileptic syndromes with continuous spikes-waves during slow sleep.

  Seizure 20111001

• Synthesis and anticonvulsant activity of novel 2,6-diketopiperazine derivatives. Part 1: perhydropyrrole[1,2-a]pyrazines.

  European journal of medicinal chemistry 20111001

• Spotlight on levetiracetam in epilepsy.

  CNS drugs 20111001

• Combining modelling and mutagenesis studies of synaptic vesicle protein 2A to identify a series of residues involved in racetam binding.

  Biochemical Society transactions 20111001

• [Frontal lobe nocturnal epilepsy in an adult with Gilles de la Tourette syndrome].

  Revista de neurologia 20111001

• Steady-state pharmacokinetics of intravenous levetiracetam in neurocritical care patients.

  Pharmacotherapy 20111001

• Canine status epilepticus: a translational platform for human therapeutic trials.

  Epilepsia 20111001

• What is the evidence to use new intravenous AEDs in status epilepticus?

  Epilepsia 20111001

• A prehospital randomized trial in convulsive status epilepticus.

  Epilepsia 20111001

• Status epilepticus-induced hyperemia and brain tissue hypoxia after cardiac arrest.

  Archives of neurology 20111001

• Levetiracetam.

  The Journal of the Association of Physicians of India 20111001

• Levetiracetam monotherapy--outcomes from an epilepsy clinic.

  Seizure 20110901

• A new mechanism for antiepileptic drug action: vesicular entry may mediate the effects of levetiracetam.

  Journal of neurophysiology 20110901

• [Paroxysmal tonic upward gaze deviation triggered by valproic acid within the context of focal epilepsy].

  Revista de neurologia 20110901

• Perioral myoclonia with absences and myoclonic status aggravated by oxcarbazepine.

  Epileptic disorders : international epilepsy journal with videotape 20110901

• Pharmacokinetics of levetiracetam after oral and intravenous administration of a single dose to clinically normal cats.

  American journal of veterinary research 20110901

• Short report: A calcified Taenia solium granuloma associated with recurrent perilesional edema causing refractory seizures: histopathological features.

  The American journal of tropical medicine and hygiene 20110901

• Levetiracetam exhibits protective properties on rat Schwann cells in vitro.

  Journal of the peripheral nervous system : JPNS 20110901

• Neuroprotective effect of levetiracetam on hippocampal sclerosis-like change in spontaneously epileptic rats.

  Brain research bulletin 20110810

• Antiepileptic drugs for treating seizures in adults with brain tumours.

  The Cochrane database of systematic reviews 20110810

• Synaptic vesicle protein 2A predicts response to levetiracetam in patients with glioma.

  Neurology 20110809

• Levetiracetam is associated with improved cognitive outcome for patients with intracranial hemorrhage.

  Neurocritical care 20110801

• Epilepsy and trimethylaminuria: A new case report and literature review.

  Brain & development 20110801

• Levetiracetam monotherapy in patients with brain tumor-related epilepsy: seizure control, safety, and quality of life.

  Journal of neuro-oncology 20110801

• Motor symptoms of schizophrenia: is tardive dyskinesia a symptom or side effect? A modern treatment.

  Current psychiatry reports 20110801

• No effect of oral contraceptives on the metabolism of levetiracetam.

  Epilepsy research 20110801

• Postpartum cerebral venous thrombosis.

  Obstetrics and gynecology 20110801

• Pregnancy complicated by recurrent brain abscess after extraction of an infected tooth.

  Obstetrics and gynecology 20110801

• Curing of oscillating larynx by levetiracetam.

  Archives of neurology 20110801

• Cost-utility analysis of levetiracetam and phenytoin for posttraumatic seizure prophylaxis.

  The Journal of trauma 20110801

• [The effectiveness of levetiracetam in the treatment of neuropathic pain].

  Revista de neurologia 20110716

• The anticonvulsant levetiracetam for the treatment of pain in polyneuropathy: a randomized, placebo-controlled, cross-over trial.

  European journal of pain (London, England) 20110701

• Second-line status epilepticus treatment: comparison of phenytoin, valproate, and levetiracetam.

  Epilepsia 20110701

• Effects of antiepileptic drugs on GABA release from rat and human neocortical synaptosomes.

  Naunyn-Schmiedeberg's archives of pharmacology 20110701

• A randomized, double-blind, placebo-controlled trial of levetiracetam for dyskinesia in Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20110701

• Pregabalin or placebo used adjunctively with levetiracetam in refractory partial-onset epilepsy: a post hoc efficacy and safety analysis in combined clinical trials.

  Current medical research and opinion 20110701

• Pharmacokinetics of levetiracetam in neonates with seizures.

  The Journal of pediatrics 20110701

• Effects of early long-term treatment with antiepileptic drugs on development of seizures and depressive-like behavior in a rat genetic absence epilepsy model.

  Epilepsia 20110701

• Clinical comparability of the new antiepileptic drugs in refractory partial epilepsy: a systematic review and meta-analysis.

  Epilepsia 20110701

• Evaluation of the subjective and reinforcing effects of diphenhydramine, levetiracetam, and valproic acid.

  Journal of psychopharmacology (Oxford, England) 20110601

• 11-Deoxycortisol impedes GABAergic neurotransmission and induces drug-resistant status epilepticus in mice.

  Neuropharmacology 20110601

• Restless Leg Syndrome in ADHD children: levetiracetam as a reasonable therapeutic option.

  Brain & development 20110601

• Levetiracetam in the management of bipolar depression: a randomized, double-blind, placebo-controlled trial.

  The Journal of clinical psychiatry 20110601

• Clinical diagnosis and successful treatment of inflammatory cerebral amyloid angiopathy.

  Neurocritical care 20110601

• The use of lacosamide in refractory status epilepticus.

  Neurocritical care 20110601

• Levetiracetam efficacy in patients with Lennox-Gastaut syndrome. Presentation of a case.

  Neurologia (Barcelona, Spain) 20110601

• The effects of valproic acid and levetiracetam on chicken embryos.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20110601

• A combination of levetiracetam and tiapride for outpatient alcohol detoxification: a case series.

  Journal of addiction medicine 20110601

• Levetiracetam in children and adolescents with epilepsy and hemiplegic cerebral palsy.

  Journal of paediatrics and child health 20110501

• A prospective open-labeled trial with levetiracetam in pediatric epilepsy syndromes: continuous spikes and waves during sleep is definitely a target.

  Seizure 20110501

• The safety and efficacy of add-on levetiracetam in elderly patients with focal epilepsy: a one-year observational study.

  Seizure 20110501

• Early treatment after stroke for the prevention of late epileptic seizures: a report on the problems performing a randomised placebo-controlled double-blind trial aimed at anti-epileptogenesis.

  Seizure 20110501

• The effect of levetiracetam monotherapy on subjective sleep quality and objective sleep parameters in patients with epilepsy: compared with the effect of carbamazepine-CR monotherapy.

  Seizure 20110501

• Effect of valproate, lamotrigine and levetiracetam on excitability and firing properties of CA1 neurons in rat brain slices.

  Cellular and molecular neurobiology 20110501

• Conclusions of the available meta-analyses exploring the efficacy of levetiracetam.

  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20110501

• Meta-analysis of randomized trials on first line and adjunctive levetiracetam.

  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20110501

• Generic substitution of levetiracetam resulting in increased incidence of breakthrough seizures.

  The Annals of pharmacotherapy 20110501

• [Effects of levetiracetam on the expression of NCAM and GAP-43 mRNA in the hippocampus of rats with epilepsy].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20110501

• Anxiety and predisposition to audiogenic epilepsy in rats of different genotypes.

  Bulletin of experimental biology and medicine 20110501

• Role of Ca(V)2.1-mediated NMDA receptor signaling in the nucleus accumbens in spatial short-term memory.

  Behavioural brain research 20110415

• Tonic seizures: a diagnostic clue of anti-LGI1 encephalitis?

  Neurology 20110412

• Levetiracetam in brain ischemia: clinical implications in neuroprotection and prevention of post-stroke epilepsy.

  Brain & development 20110401

• Levetiracetam in chronic daily headache: a double-blind, randomised placebo-controlled study. (The Australian KEPPRA Headache Trial [AUS-KHT]).

  Cephalalgia : an international journal of headache 20110401

• Nocturnal frontal lobe epilepsy presenting with restless leg syndrome-like symptoms.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20110401

• Successful treatment of refractory simple motor status epilepticus with lacosamide and levetiracetam.

  Seizure 20110401

• Levetiracetam for treatment of neonatal seizures.

  Journal of child neurology 20110401

• Simultaneous quantification of levetiracetam and gabapentin in plasma by ultra-pressure liquid chromatography coupled with tandem mass spectrometry detection.

  Therapeutic drug monitoring 20110401

• A multicenter, randomized, placebo-controlled trial of levetiracetam in children and adolescents with newly diagnosed absence epilepsy.

  Epilepsia 20110401

• Safety of non-therapeutic levetiracetam ingestions--a poison center based study.

  Pharmacoepidemiology and drug safety 20110401

• Use of intravenous levetiracetam for management of acute seizures in neonates.

  Pediatric neurology 20110401

• Clinical experience with generic levetiracetam in people with epilepsy.

  Epilepsia 20110401

• [Efficacy of new antiepileptic drugs and the next generation drugs].

  Brain and nerve = Shinkei kenkyu no shinpo 20110401

• Childhood febrile convulsions and déjà vu in adulthood.

  British journal of hospital medicine (London, England : 2005) 20110401

• [Rational combinations of antiepileptic drugs for refractory epilepsy].

  Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20110401

• Voluntary alcohol consumption and plasma beta-endorphin levels in alcohol preferring rats chronically treated with levetiracetam: a preliminary study.

  Physiology & behavior 20110328

• Levetiracetam: a review of its use in epilepsy.

  Drugs 20110305

• Elderly patient with acquired long QT syndrome secondary to Levetiracetam.

  Neurologia (Barcelona, Spain) 20110301

• Early valproic acid exposure alters functional organization in the primary visual cortex.

  Experimental neurology 20110301

• Elderly patients with migraine: an open-label study on prophylaxis therapy with levetiracetam.

  Central nervous system agents in medicinal chemistry 20110301

• Influence of enzyme inducing antiepileptic drugs on the pharmacokinetics of levetiracetam in patients with epilepsy.

  Epilepsy research 20110301

• [Transient splenial lesion in influenza A H1N1 2009 infection].

  Der Radiologe 20110301

• Protein kinase inhibitor as a potential candidate for epilepsy treatment.

  Epilepsia 20110301

• [Are clinical features derived from evidences and experiences outside of Japan applicable to clinical practices in Japan? Comparisons of results among studies conducted in US, Europe, Asian Countries and Japan].

  Brain and nerve = Shinkei kenkyu no shinpo 20110301

• The efficacy of bromides, stiripentol and levetiracetam in two patients with malignant migrating partial seizures in infancy.

  Epileptic disorders : international epilepsy journal with videotape 20110301

• Efficacy and tolerability of levetiracetam in children with epilepsy.

  Brain & development 20110201

• Neurocognitive effects of brivaracetam, levetiracetam, and lorazepam.

  Epilepsia 20110201

• Status epilepticus.

  Indian journal of pediatrics 20110201

• Performance characteristics of a new levetiracetam immunoassay and method comparison with a high-performance liquid chromatography method.

  Therapeutic drug monitoring 20110201

• Higher evening antiepileptic drug dose for nocturnal and early-morning seizures.

  Epilepsy & behavior : E&B 20110201

• The pharmacokinetics of levetiracetam in healthy dogs concurrently receiving phenobarbital.

  Journal of veterinary pharmacology and therapeutics 20110201

• Suspected phenobarbital-induced pseudolymphoma in a cat.

  Journal of the American Veterinary Medical Association 20110201

• [Pharmacology and clinical results of levetiracetam (E Keppra(®) Tablets), a new antiepileptic drug].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20110201

• Levetiracetam for the management of levodopa-induced dyskinesias in Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20110201

• Prophylactic anticonvulsants after subarachnoid hemorrhage.

  World neurosurgery 20110201

• Comparison of short-duration levetiracetam with extended-course phenytoin for seizure prophylaxis after subarachnoid hemorrhage.

  World neurosurgery 20110201

• Child development following in utero exposure: levetiracetam vs sodium valproate.

  Neurology 20110125

• Carbamazepine in pregnancy: Levetiracetam and lamotrigine are better options.

  BMJ (Clinical research ed.) 20110125

• Probable psychosis associated with levetiracetam: a case report.

  Progress in neuro-psychopharmacology & biological psychiatry 20110115

• BsmI vitamin D receptor's polymorphism and bone mineral density in men and premenopausal women on long-term antiepileptic therapy.

  European journal of neurology 20110101

• Perioperative levetiracetam for prevention of seizures in supratentorial brain tumor surgery.

  Journal of neuro-oncology 20110101

• Improvement of early diagnosed post-anoxic myoclonus with levetiracetam.

  Intensive care medicine 20110101

• Increased compactibility of acetames after roll compaction.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20110101

• Anti-inflammatory effects of the anticonvulsant drug levetiracetam on electrophysiological properties of astroglia are mediated via TGFβ1 regulation.

  British journal of pharmacology 20110101

• Non-convulsive status epilepticus in the postanesthesia care unit following meningioma excision.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20110101

• Levetiracetam: safety and efficacy in neonatal seizures.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20110101

• The EULEV cohort study: rates of and factors associated with continuation of levetiracetam after 1 year.

  British journal of clinical pharmacology 20110101

• Efficacy of intravenous levetiracetam as an add-on treatment in status epilepticus: a multicentric observational study.

  Seizure 20110101

• Levetiracetam, seizures, and suicidality.

  Harvard review of psychiatry 20110101

• [Effectiveness of levetiracetam in the treatment of two cases of hypoxic encephalopathy with myoclonic status].

  Medicina intensiva 20110101

• Levetiracetam protects hippocampal neurons in culture against hypoxia-induced injury.

  Folia histochemica et cytobiologica 20110101

• Haematological side effects of antiepileptic drug treatment in patients with epilepsy.

  Acta neurologica Scandinavica. Supplementum 20110101

• Paradoxical seizures and status epilepticus with newer antiepileptic drugs.

  Neurology India 20110101

• Probable psychosis associated with levetiracetam: a case report.

  The Journal of neuropsychiatry and clinical neurosciences 20110101

• Incidence of postoperative seizures with and without levetiracetam pretreatment in dogs undergoing portosystemic shunt attenuation.

  Journal of veterinary internal medicine 20110101

• Effects of valproic acid (VPA) and levetiracetam (LEV) on proliferation, apoptosis and hormone secretion of the human choriocarcinoma BeWo cell line.

  Pharmacological reports : PR 20110101

• Levetiracetam reverses synaptic deficits produced by overexpression of SV2A.

  PloS one 20110101

• [The retrospective study of efficacy and safety of levetiracetam as an add-on treatment of epilepsy in children].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101

• [Transitory cognitive dysfunction in rolandic epilepsy].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101

• [Idiopathic focal epilepsies of infancy and childhood].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101

• [Epilepsies with electric status epilepticus in sleep: peculiarities of clinical course and rational approaches to treatment].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101

• Recurrent sinus arrest and asystole due to breath-holding spell in a toddler; recovery with levetiracetam-therapy.

  Circulation 20101221

• In reference to Usery JB et al. (J Neuro-oncol. 2010 Feb 10).

  Journal of neuro-oncology 20101201

• Seizures in patients with glioma treated with phenytoin and levetiracetam.

  Journal of neurosurgery 20101201

• A case of levetiracetam-induced thrombocytopenia.

  Epileptic disorders : international epilepsy journal with videotape 20101201

• Levetiracetam for the treatment of alcohol withdrawal syndrome: a multicenter, prospective, randomized, placebo-controlled trial.

  Journal of clinical psychopharmacology 20101201

• Anti-convulsants and gene expression in malignant gliomas.

  Neurosurgery 20101201

• Levetiracetam-induced thrombocytopenia among inpatients: a retrospective study.

  Epilepsia 20101201

• Acute levetiracetam overdose presented with mild adverse events.

  Acta neurologica Taiwanica 20101201

• Clinical and neuropsychological considerations in a case of unrecognized myoclonic epileptic jerks dramatically controlled by levetiracetam.

  Neuropediatrics 20101201

• Cortico-hippocampal hyperexcitability in synapsin I/II/III knockout mice: age-dependency and response to the antiepileptic drug levetiracetam.

  Neuroscience 20101124

• Effects of levetiracetam on blood-brain barrier disturbances following hyperthermia-induced seizures in rats with cortical dysplasia.

  Life sciences 20101120

• Inhibitory effects of levetiracetam on absence seizures in a novel absence-like epilepsy animal model, Groggy rat.

  Brain research 20101104

• The effect of valproate and levetiracetam on steroidogenesis in forskolin-stimulated H295R cells.

  Epilepsia 20101101

• Levetiracetam for levodopa-induced dyskinesia in Parkinson's disease: a randomized, double-blind, placebo-controlled trial.

  Journal of neural transmission (Vienna, Austria : 1996) 20101101

• Cross-reactivity of skin rashes with current antiepileptic drugs in Chinese population.

  Seizure 20101101

• Nonepileptic seizures under levetiracetam therapy.

  Epilepsy & behavior : E&B 20101101

• Effect of levetiracetam on testosterone levels in male patients.

  Epilepsia 20101101

• [Clinical characteristics and treatment for new onset epilepsy in the elderly].

  Rinsho shinkeigaku = Clinical neurology 20101101

• Subthreshold pharmacological and genetic approaches to analyzing CaV2.1-mediated NMDA receptor signaling in short-term memory.

  European journal of pharmacology 20101025

• Synergistic neuroprotective therapies with hypothermia.

  Seminars in fetal & neonatal medicine 20101001

• The effects of levetiracetam on urinary 15f-2t-isoprostane levels in epileptic patients.

  Seizure 20101001

• Intramuscular and intravenous levetiracetam in humans: safety and pharmacokinetics.

  Epilepsy research 20101001

• Age and comedications influence levetiracetam pharmacokinetics in children.

  Pediatric neurology 20101001

• Adjunctive levetiracetam in patients aged 1 month to <4 years with partial-onset seizures: subpopulation analysis of a prospective, open-label extension study of up to 48 weeks.

  Clinical therapeutics 20101001

• Tissue distribution of newer anticonvulsant drugs in postmortem cases.

  Journal of analytical toxicology 20101001

• [Levetiracetam-associated hyponatremia].

  Medicina clinica 20100918

• Levetiracetam suppresses development of spontaneous EEG seizures and aberrant neurogenesis following kainate-induced status epilepticus.

  Brain research 20100917

• A prospective evaluation and literature review of levetiracetam use in patients with brain tumors and seizures.

  Journal of neuro-oncology 20100901

• Region-specific changes in gene expression in rat brain after chronic treatment with levetiracetam or phenytoin.

  Epilepsia 20100901

• Levetiracetam enhances p53-mediated MGMT inhibition and sensitizes glioblastoma cells to temozolomide.

  Neuro-oncology 20100901

• Reversible blindness: simple partial seizures presenting as ictal and postictal hemianopsia.

  Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 20100901

• Levetiracetam-mediated emotional behavior in heterozygous rolling Nagoya Ca(V)2.1 channel mutant mice.

  Pharmacology, biochemistry, and behavior 20100901

• Decrease in propagation of interictal epileptiform activity after introduction of levetiracetam visualized with electric source imaging.

  Brain topography 20100901

• Efficacy and tolerability of high oral doses of levetiracetam in children with epilepsy.

  Epilepsy research 20100901

• The antihyperalgesic effect of levetiracetam in an inflammatory model of pain in rats: mechanism of action.

  British journal of pharmacology 20100901

• An observational trial to investigate the efficacy and tolerability of levetiracetam in trigeminal neuralgia.

  Headache 20100901

• Acceptability and tolerability of levetiracetam oral solution for the treatment of partial-onset seizures: the SOLUCIÓN study.

  Methods and findings in experimental and clinical pharmacology 20100901

• Assessment of levetiracetam bioavailability from targeted sites in the human intestine using remotely activated capsules and gamma scintigraphy: Open-label, single-dose, randomized, four-way crossover study in healthy male volunteers.

  Clinical therapeutics 20100901

• Comparison of the antiepileptogenic effects of an early long-term treatment with ethosuximide or levetiracetam in a genetic animal model of absence epilepsy.

  Epilepsia 20100801

• Alterations of intracerebral γ-aminobutyric acid (GABA) levels by titration with levetiracetam in patients with focal epilepsies.

  Epilepsia 20100801

• Intravenous levetiracetam in the management of acute seizures in children.

  Pediatric neurology 20100801

• Efficacy of levetiracetam in children with refractory epilepsy as an add-on trial.

  Epilepsy research 20100801

• Tuberous sclerosis.

  JPMA. The Journal of the Pakistan Medical Association 20100801

• [Myoclonias with a propiospinal and radicular origin: their response to levetiracetam].

  Revista de neurologia 20100716

• High-dose intravenous levetiracetam for acute seizure exacerbation in children with intractable epilepsy.

  Epilepsia 20100701

• Efficacy and safety of levetiracetam for outpatient alcohol detoxification.

  Pharmacopsychiatry 20100701

• Assessment of behavioral and emotional functioning using standardized instruments in children and adolescents with partial-onset seizures treated with adjunctive levetiracetam in a randomized, placebo-controlled trial.

  Epilepsy & behavior : E&B 20100701

• [Prophylactic efficacy of levetiracetam, valproate or phenobarbital on febrile convulsions in rats].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20100701

• [Levetiracetam modifies the pattern of audiogenic locomotive response in Wistar and Krushinsky-Molodkina strain rats].

  Eksperimental'naia i klinicheskaia farmakologiia 20100701

• Juvenile myoclonic epilepsy.

  Neurosciences (Riyadh, Saudi Arabia) 20100701

• Sequential intrarectal diazepam and intravenous levetiracetam in treating acute repetitive and prolonged seizures.

  Epilepsia 20100601

• Levetiracetam in submaximal subcutaneous pentylentetrazol-induced seizures in rats.

  Seizure 20100601

• Generalized seizures aggravated by levetiracetam in an adult patient with phenylketonuria.

  Metabolic brain disease 20100601

• Effect of levetiracetam on hippocampal protein expression and cell proliferation in rats.

  Epilepsy research 20100601

• Improvement of myoclonic epilepsy in Down syndrome treated with levetiracetam.

  Epileptic disorders : international epilepsy journal with videotape 20100601

• Levetiracetam-induced seizure aggravation associated with continuous spikes and waves during slow sleep in children with refractory epilepsies.

  Epileptic disorders : international epilepsy journal with videotape 20100601

• Levetiracetam in childhood epilepsy.

  Paediatric drugs 20100601

• Intravenous Levetiracetam as first-line treatment of status epilepticus in the elderly.

  Acta neurologica Scandinavica 20100601

• Effect of prenatal levetiracetam exposure on motor and cognitive functions of rat offspring.

  Brain & development 20100501

• Efficacy and safety of levetiracetam as an add-on therapy in children aged less than 4 years with refractory epilepsy.

  Journal of child neurology 20100501

• Seizure risk in brain tumor patients with conversion to generic levetiracetam.

  Journal of neuro-oncology 20100501

• Levetiracetam in generalized social anxiety disorder: a double-blind, randomized controlled trial.

  The Journal of clinical psychiatry 20100501

• Transient improvement after brief antiepileptic drug withdrawal in the epilepsy monitoring unit--possible relationship to AED tolerance.

  Epilepsia 20100501

• Antiepileptogenic and anticonvulsive actions of levetiracetam in a pentylenetetrazole kindling model.

  Epilepsy research 20100501

• Intravenous levetiracetam in children with seizures: a prospective safety study.

  Journal of child neurology 20100501

• [Antiepileptic drugs in North America].

  Brain and nerve = Shinkei kenkyu no shinpo 20100501

• Cognitive outcome of antiepileptic treatment with levetiracetam versus carbamazepine monotherapy: a non-interventional surveillance trial.

  Epilepsy & behavior : E&B 20100501

• Efficacy and safety of levetiracetam as adjunctive therapy in adult patients with uncontrolled partial epilepsy: the Asia SKATE II Study.

  Epilepsy & behavior : E&B 20100501

• The tolerability and efficacy of levetiracetam.

  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20100501

• Levetiracetam in clinical practice: efficacy and tolerability in epilepsy.

  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20100501

• Effects of valproate, carbamazepine, and levetiracetam on the antioxidant and oxidant systems in epileptic patients and their clinical importance.

  Clinical neuropharmacology 20100501

• Prospective, randomized, single-blinded comparative trial of intravenous levetiracetam versus phenytoin for seizure prophylaxis.

  Neurocritical care 20100401

• [Which factors have an impact on levetiracetam serum concentrations? An analysis in 163 patients with epilepsy].

  Der Nervenarzt 20100401

• Levetiracetam in the treatment of neonatal seizures: a pilot study.

  Seizure 20100401

• Levetiracetam, lamotrigine, and phenobarbital in patients with epileptic seizures and Alzheimer's disease.

  Epilepsy & behavior : E&B 20100401

• Comparative effectiveness of 10 antiepileptic drugs in older adults with epilepsy.

  Archives of neurology 20100401

• [Efficacy and safety of adjunctive levetiracetam in children younger than 4 years with refractory epilepsy].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20100401

• Separate episodes of delirium associated with levetiracetam and amiodarone treatment in an elderly woman.

  The American journal of geriatric pharmacotherapy 20100401

• Dose-related levetiracetam-induced reticulated drug eruption.

  Journal of drugs in dermatology : JDD 20100401

• Rapid improvement of neuroleptic-induced tardive dyskinesia with levetiracetam in an interictal psychotic patient.

  Journal of clinical psychopharmacology 20100401

• Levetiracetam inhibits interleukin-1 beta inflammatory responses in the hippocampus and piriform cortex of epileptic rats.

  Neuroscience letters 20100303

• Levetiracetam: a practical option for seizure management in elderly patients with cognitive impairment.

  American journal of Alzheimer's disease and other dementias 20100301

• Levetiracetam in nonconvulsive status epilepticus in a child with Angelman syndrome.

  Journal of child neurology 20100301

• Improved seizure control by alternating therapy of levetiracetam and valproate in epileptic rats.

  Epilepsia 20100301

• LC method for therapeutic drug monitoring of levetiracetam: evaluation of the assay performance and validation of its application in the routine area.

  Clinical biochemistry 20100301

• Simultaneous determination of levetiracetam and its acid metabolite (ucb L057) in serum/plasma by liquid chromatography tandem mass spectrometry.

  Clinical biochemistry 20100301

• Treatment strategies targeting excess hippocampal activity benefit aged rats with cognitive impairment.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100301

• Management of refractory status epilepticus at a tertiary care centre in a developing country.

  Seizure 20100301

• Quantification of levetiracetam in plasma of neonates by ultra performance liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100301

• Unexpected gamma glutamyltransferase rise increase during levetiracetam monotherapy.

  Epileptic disorders : international epilepsy journal with videotape 20100301

• Levetiracetam pharmacokinetics in healthy dogs following oral administration of single and multiple doses.

  American journal of veterinary research 20100301

• Efficacy and safety of levetiracetam in patients with glioma: a clinical prospective study.

  Archives of neurology 20100301

• Seizure management in a complex hospice patient.

  Journal of pain & palliative care pharmacotherapy 20100301

• Emergent complications of the newer anticonvulsants.

  The Journal of emergency medicine 20100201

• Successful treatment for refractory convulsive status epilepticus by non-parenteral lacosamide.

  Epilepsia 20100201

• Interactions between antiepileptic and chemotherapeutic drugs in children with brain tumors: is it time to change treatment?

  Pediatric blood & cancer 20100201

• Levetiracetam inhibits kindling-induced synaptic potentiation in the dentate gyrus of freely moving rats.

  Neuroscience research 20100201

• Efficacy of levetiracetam in the treatment of drug-resistant Rett syndrome.

  Epilepsy research 20100201

• Long-term levetiracetam treatment in patients with epilepsy: 3-year follow up.

  Acta neurologica Scandinavica 20100201

• Effects of levetiracetam and valproic acid monotherapy on sex-steroid hormones in prepubertal children--results from a pilot study.

  Epilepsy research 20100201

• Discovery of indolone acetamides as novel SV2A ligands with improved potency toward seizure suppression.

  ChemMedChem 20100201

• Levetiracetam as add-on therapy in different subgroups of 'benign' idiopathic focal epilepsies in childhood.

  Epilepsy & behavior : E&B 20100201

• Dose-dependent oxcarbazepine-related anorgasmia.

  Epilepsy & behavior : E&B 20100201

• Efficacy and safety of adjunctive levetiracetam therapy in pediatric intractable epilepsy.

  Pediatric neurology 20100201

• Levetiracetam: a comprehensive review.

  Expert review of neurotherapeutics 20100201

• [Levetiracetam therapy for childhood epilepsy: a systematic review].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20100201

• Effects of levetiracetam on hippocampal kindling in Noda epileptic rats.

  Brain research 20100114

• Levetiracetam as monotherapy for seizures in a neonate with acute lymphoblastic leukemia.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20100101

• Vomiting due to intravenous levetiracetam in a case of Creutzfeldt-Jakob disease.

  Epilepsy & behavior : E&B 20100101

• Intravenous levetiracetam in the rat pilocarpine-induced status epilepticus model: behavioral, physiological and histological studies.

  Neuropharmacology 20100101

• Levetiracetam attenuates hippocampal expression of synaptic plasticity-related immediate early and late response genes in amygdala-kindled rats.

  BMC neuroscience 20100101

• Heavy metals testing in active pharmaceutical ingredients: an alternate approach.

  Die Pharmazie 20100101

• [Therapeutic drug monitoring of levetiracetam].

  Therapie 20100101

• Severe acute hepatitis in the DRESS syndrome: Report of two cases.

  Annals of hepatology 20100101

• Cardiovascular risk factors in epilepsy patients taking levetiracetam, carbamazepine or lamotrigine.

  Acta neurologica Scandinavica. Supplementum 20100101

• Catatonia after right temporal lobe resection.

  The Journal of neuropsychiatry and clinical neurosciences 20100101

• Reversed-phase HPLC analysis of levetiracetam in tablets using monolithic and conventional C18 silica columns.

  Journal of AOAC International 20100101

• [Monotherapy with levetiracetam in adult patients with partial epilepsy].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101

• Role of levetiracetam in refractory seizures due to a rare progressive myoclonic epilepsy: Lafora body disease.

  BMJ case reports 20100101

• Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.

  Journal of medicinal chemistry 20091210

• [Antiepileptic drugs for the prevention of pediatric migraine].

  Revue neurologique 20091201

• Levetiracetam in spinal cord injury pain: a randomized controlled trial.

  Spinal cord 20091201

• Horseradish peroxidase covalent grafting onto screen-printed carbon electrodes for levetiracetam chronoamperometric determination.

  Analytical biochemistry 20091201

• Levetiracetam reduces myoclonus in corticobasal degeneration: report of two cases.

  Journal of neural transmission (Vienna, Austria : 1996) 20091201

• Epilepsia partialis continua responsive to intravenous levetiracetam.

  Seizure 20091201

• Blood pressure changes after intravenous fosphenytoin and levetiracetam in patients with acute cerebral symptoms.

  Epilepsy research 20091201

• Utility of levetiracetam in patients with subarachnoid hemorrhage.

  Seizure 20091201

• Levetiracetam inhibits glutamate transmission through presynaptic P/Q-type calcium channels on the granule cells of the dentate gyrus.

  British journal of pharmacology 20091201

• What is the relative value of the standard anticonvulsants: Phenytoin and fosphenytoin, phenobarbital, valproate, and levetiracetam?

  Epilepsia 20091201

• Correspondence on ''the unrecognized epilepsy spectrum: the effects of levetiracetam on neuropsychological functioning in relation to subclinical spike production''.

  Journal of child neurology 20091201

• Experimental and simulation studies on the mechanisms of levetiracetam-mediated inhibition of delayed-rectifier potassium current (KV3.1): contribution to the firing of action potentials.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20091201

• Contraindications to phenytoin in emergency department patients with seizures.

  The Journal of emergency medicine 20091101

• Levetiractam in the treatment of two children with myoclonic status epilepticus.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20091101

• An open-label, prospective study of levetiracetam in children and adolescents with Tourette syndrome.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20091101

• Epilepsy in Angelman syndrome: a questionnaire-based assessment of the natural history and current treatment options.

  Epilepsia 20091101

• Isobolographic characterization of the anticonvulsant interaction profiles of levetiracetam in combination with clonazepam, ethosuximide, phenobarbital and valproate in the mouse pentylenetetrazole-induced seizure model.

  Seizure 20091101

• Levetiracetam has a time- and stimulation-dependent effect on synaptic transmission.

  Seizure 20091101

• Neurocognitive effects of adjunctive levetiracetam in children with partial-onset seizures: a randomized, double-blind, placebo-controlled, noninferiority trial.

  Epilepsia 20091101

• Levetiracetam monotherapy for childhood occipital epilepsy of gastaut.

  Acta neurologica Scandinavica 20091101

• Clinical efficacy and cognitive and neuropsychological effects of levetiracetam in epilepsy: an open-label multicenter study.

  Epilepsy & behavior : E&B 20091101

• Experience with intravenous levetiracetam in status epilepticus: a retrospective case series.

  CNS drugs 20091101

• [The use of intravenous levetiracetam in a general hospital].

  Revista de neurologia 20091101

• [Effectiveness of levetiracetam in a patient with chronic motor tics, Rolandic epilepsy and attentional and behavioural disorder].

  Revista de neurologia 20091101

• Intravenous levetiracetam as treatment for status epilepticus.

  Journal of neurology 20091001

• Levetiracetam in children with refractory epilepsy: lack of correlation between plasma concentration and efficacy.

  Seizure 20091001

• Isobolographic characterization of interactions of levetiracetam with the various antiepileptic drugs in the mouse 6 Hz psychomotor seizure model.

  Epilepsy research 20091001

• Levetiracetam use in pregnancy.

  The Annals of pharmacotherapy 20091001

• Levetiracetam extended release and levetiracetam immediate release as adjunctive treatment for partial-onset seizures: an indirect comparison of treatment-emergent adverse events using meta-analytic techniques.

  Epilepsy & behavior : E&B 20091001

• Differential effects of levetiracetam, carbamazepine, and lamotrigine on reproductive endocrine function in adults.

  Epilepsy & behavior : E&B 20091001

• Probable levetiracetam-associated depression in the elderly: two case reports.

  The American journal of geriatric pharmacotherapy 20091001

• Thrombocytopenia as an adverse effect of levetiracetam therapy in a child.

  Neuropediatrics 20091001

• Efficacy of anti-epileptic drugs in patients with gliomas and seizures.

  Journal of neurology 20090901

• Levetiracetam-induced platelet dysfunction.

  Epilepsy research 20090901

• Intravenous levetiracetam terminates refractory status epilepticus in two patients with migrating partial seizures in infancy.

  Epilepsy research 20090901

• The use of antiepileptic drugs in pediatric brain tumor patients.

  Pediatric neurology 20090901

• The first line of therapy in a girl with juvenile myoclonic epilepsy: should it be valproate or a new agent?

  Epilepsia 20090901

• Termination of complex partial status epilepticus by intravenous levetiracetam.

  Journal of neurology, neurosurgery, and psychiatry 20090801

• Open-label pilot trial of levetiracetam for cramps and spasticity in patients with motor neuron disease.

  Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20090801

• Rapid infusion of a loading dose of intravenous levetiracetam with minimal dilution: a safety study.

  Journal of child neurology 20090801

• Quality of life and seizure control in patients with brain tumor-related epilepsy treated with levetiracetam monotherapy: preliminary data of an open-label study.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20090801

• Efficacy and safety of levetiracetam in the treatment of Panayiotopoulos syndrome.

  Epilepsy research 20090801

• Effects of levetiracetam and valproate on reproductive endocrine function studied in human ovarian follicular cells.

  Epilepsia 20090801

• A family with paroxysmal nonkinesigenic dyskinesia: genetic and treatment issues.

  Pediatric neurology 20090801

• Two years of experience in the treatment of status epilepticus with intravenous levetiracetam.

  Epilepsy & behavior : E&B 20090801

• Ion chromatographic determination of residual phase transfer catalyst in active pharmaceutical ingredient.

  Journal of chromatographic science 20090801

• Levetiracetam decreases the seizure activity and blood-brain barrier permeability in pentylenetetrazole-kindled rats with cortical dysplasia.

  Brain research 20090724

• Efficacy and tolerability of levetiracetam versus phenytoin after supratentorial neurosurgery.

  Neurology 20090714

• Safety and feasibility of switching from phenytoin to levetiracetam monotherapy for glioma-related seizure control following craniotomy: a randomized phase II pilot study.

  Journal of neuro-oncology 20090701

• The underrecognized epilepsy spectrum: the effects of levetiracetam on neuropsychological functioning in relation to subclinical spike production.

  Journal of child neurology 20090701

• Brivaracetam inhibits spreading depression in rat neocortical slices in vitro.

  Seizure 20090701

• Impact of levetiracetam add-on therapy on different EEG occipital frequencies in epileptic patients.

  Seizure 20090701

• Intravenous levetiracetam in critically ill children with status epilepticus or acute repetitive seizures.

  Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20090701

• Levetiracetam as add-on therapy for idiopathic generalized epilepsy syndromes with onset during adolescence: analysis of two randomized, double-blind, placebo-controlled studies.

  Epilepsy research 20090701

• Anticonvulsant hypersensitivity syndrome presenting as aseptic meningitis.

  Journal of neurology 20090701

• Levetiracetam plasma level monitoring during pregnancy, delivery, and postpartum: clinical and outcome implications.

  Epilepsy & behavior : E&B 20090701

• Proepileptic phenotype of SV2A-deficient mice is associated with reduced anticonvulsant efficacy of levetiracetam.

  Epilepsia 20090701

• Role of intravenous levetiracetam in acute seizure management of children.

  Pediatric neurology 20090701

• Levetiracetam induced interstitial nephritis and renal failure.

  Pediatric neurology 20090701

• In the rat maximal dentate activation model of partial complex epilepsy, the anticonvulsant activity of levetiracetam is modulated by nitric oxide-active drugs.

  Journal of neural transmission (Vienna, Austria : 1996) 20090701

• [The role of the neuromodulators in the preventive treatment of migraine].

  Revista de neurologia 20090701

• A new method for quantification and assessment of epileptiform activity in EEG with special reference to focal nocturnal epileptiform activity.

  Brain topography 20090601

• Levetiracetam therapy for treatment of choreoathetosis in dyskinetic cerebral palsy.

  Developmental medicine and child neurology 20090601

• The impact of side effects on long-term retention in three new antiepileptic drugs.

  Seizure 20090601

• Successful treatment of encephalopathy and myoclonus with levetiracetam in a case of subacute sclerosing panencephalitis.

  Journal of child neurology 20090601

• Levetiracetam accumulation in renal failure causing myoclonic encephalopathy with triphasic waves.

  Seizure 20090601

• Epilepsia partialis continua successfully treated with levetiracetam.

  Journal of neurology 20090601

• Double-blind, crossover study of clonidine and levetiracetam in Tourette syndrome.

  Pediatric neurology 20090601

• Intravenous levetiracetam: a new treatment alternative for refractory status epilepticus.

  Journal of neurology, neurosurgery, and psychiatry 20090601

• Hemiballismus in subthalamic haemorrhage: efficacy of levetiracetam.

  European journal of neurology 20090601

• Pilot study to evaluate the efficacy and tolerability of levetiracetam (Keppra) in treatment of patients with trigeminal neuralgia.

  European journal of neurology 20090601

• Olfactory disturbance in Parkinson disease.

  Archives of neurology 20090601

• Is levetiracetam a treatment option for dyskinetic cerebral palsy?

  Developmental medicine and child neurology 20090601

• A prospective multi-centre open label study of the use of levetiracetam as add-on treatment in patients with epilepsy and intellectual disabilities.

  Seizure 20090501

• Population pharmacokinetics of levetiracetam and dosing recommendation in children with epilepsy.

  Epilepsia 20090501

• Adjunctive levetiracetam in infants and young children with refractory partial-onset seizures.

  Epilepsia 20090501

• A prospective pilot study of levetiracetam for body dysmorphic disorder.

  CNS spectrums 20090501

• Levetiracetam-induced pancytopenia.

  The Annals of pharmacotherapy 20090501

• [Limbic encephalitis associated to voltage dependent potassium channel antibodies: report of one case].

  Revista medica de Chile 20090501

• Levetiracetam enhances endogenous antioxidant in the hippocampus of rats: in vivo evaluation by brain microdialysis combined with ESR spectroscopy.

  Brain research 20090417

• Levetiracetam-induced depression in a 5-year-old child with partial epilepsy.

  Seizure 20090401

• Seletracetam (ucb 44212) inhibits high-voltage-activated Ca2+ currents and intracellular Ca2+ increase in rat cortical neurons in vitro.

  Epilepsia 20090401

• Effect of antiepileptic agent, levetiracetam, on urodynamic parameters and neurogenic bladder overactivity in chronically paraplegic rats.

  Urology 20090401

• [New antiepileptic drugs].

  La Revue de medecine interne 20090401

• [Drugs for status epilepticus treatment].

  Revue neurologique 20090401

• Pharmacokinetics of levetiracetam XR 500mg tablets.

  Epilepsy research 20090401

• Behavioral effects of levetiracetam mitigated by pyridoxine.

  Journal of child and adolescent psychopharmacology 20090401

• Epileptic negative myoclonus: SPECT, PET, and video/EEG studies and the dramatic effects of levetiracetam.

  Epilepsy & behavior : E&B 20090401

• Effectiveness of levetiracetam in the treatment of lumbar radiculopathy: an open-label prospective cohort study.

  PM & R : the journal of injury, function, and rehabilitation 20090401

• Levetiracetam for managing neurologic and psychiatric disorders.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090315

• [Levetiracetam use in the post-hypoxic myoclonic status].

  Medicina clinica 20090314

• Benefit of combination therapy in epilepsy: a review of the preclinical evidence with levetiracetam.

  Epilepsia 20090301

• Multicenter double-blind, randomized, placebo-controlled trial of levetiracetam as add-on therapy in Chinese patients with refractory partial-onset seizures.

  Epilepsia 20090301

• Decreased expression of synaptic vesicle protein 2A, the binding site for levetiracetam, during epileptogenesis and chronic epilepsy.

  Epilepsia 20090301

• Retention of new AEDs in institutionalized intellectually disabled patients with epilepsy.

  Seizure 20090301

• Effects of levetiracetam on generalized discharges monitored with ambulatory EEG in epileptic patients.

  Seizure 20090301

• Effects of lamotrigine compared with levetiracetam on anger, hostility, and total mood in patients with partial epilepsy.

  Epilepsia 20090301

• Safety and pharmacokinetics of intravenous levetiracetam infusion as add-on in status epilepticus.

  Epilepsia 20090301

• Symptomatic complex partial status epilepticus manifesting as utilization behavior of a mobile phone.

  Epilepsy & behavior : E&B 20090301

• Pharmacodynamic and pharmacokinetic interaction profiles of levetiracetam in combination with gabapentin, tiagabine and vigabatrin in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis.

  European journal of pharmacology 20090301

• The effect of levetiracetam on tremor severity and functionality in patients with multiple sclerosis.

  Multiple sclerosis (Houndmills, Basingstoke, England) 20090301

• Post-hypoxic myoclonic status: the prognosis is not always hopeless.

  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine 20090301

• Once-daily extended-release levetiracetam as adjunctive treatment of partial-onset seizures in patients with epilepsy: a double-blind, randomized, placebo-controlled trial.

  Epilepsia 20090301

• Effects of levetiracetam on chronic pain in multiple sclerosis: results of a pilot, randomized, placebo-controlled study.

  European journal of neurology 20090301

• Charles Bonnet syndrome disappearing with carbamazepine and valproic acid but not with levetiracetam.

  Acta neurologica Belgica 20090301

• Levetiracetam for seizures in children with brain tumors and other cancers.

  Pediatric blood & cancer 20090201

• Electrochemical determination of levetiracetam by screen-printed based biosensors.

  Bioelectrochemistry (Amsterdam, Netherlands) 20090201

• Intravenous levetiracetam terminates refractory focal status epilepticus.

  Neurocritical care 20090101

• Retention rates of new antiepileptic drugs in localization-related epilepsy: a single-center study.

  Acta neurologica Scandinavica 20090101

• Phenobarbital withdrawal seizures may occur over several weeks before remitting: human data and hypothetical mechanism.

  Seizure 20090101

• Rapid effect of levetiracetam in a case of juvenile myoclonic epilepsy.

  Epilepsy & behavior : E&B 20090101

• Levetiracetam in children with refractory status epilepticus.

  Epilepsy & behavior : E&B 20090101

• Intravenous levetiracetam for epileptic seizure emergencies in older people.

  Gerontology 20090101

• No major role of common SV2A variation for predisposition or levetiracetam response in epilepsy.

  Epilepsy research 20090101

• Efficacy and safety of levetiracetam (3,000 mg/Day) as an adjunctive therapy in Chinese patients with refractory partial seizures.

  European neurology 20090101

• Safety and efficacy of levetiracetam for critically ill patients with seizures.

  Neurocritical care 20090101

• Pharmacologic treatment for the core deficits and associated symptoms of autism in children.

  Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners 20090101

• [Role of monotherapy with new antiepileptic drugs in the treatment of childhood epilepsy].

  Medicina 20090101

• [When a seizure occurs...].

  Revue medicale de Liege 20090101

• Linezolid-induced complex partial seizures in a patient with epilepsy.

  Scandinavian journal of infectious diseases 20090101

• Levetiracetam improves intention tremor in fragile x-associated tremor/ataxia syndrome.

  Clinical neuropharmacology 20090101

• Differential effects of antiepileptic drugs on steroidogenesis in a human in vitro cell model.

  Acta neurologica Scandinavica. Supplementum 20090101

• Dramatic effect of levetiracetam on posthypoxic myoclonus: difficult weaning from mechanical ventilation.

  Clinical neuropharmacology 20090101

• Pancytopenia associated with levetiracetam treatment.

  Clinical drug investigation 20090101

• [Juvenile myoclonic epilepsy with recurrent myoclonic status: efficacy of valproate].

  Therapie 20090101

• Face-related ictal hallucinations and illusions and reflex-type phenomena.

  The Journal of neuropsychiatry and clinical neurosciences 20090101

• [Levetiracetam (keppra) in the treatment of different epileptic syndromes in adults].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101

• Brivaracetam and seletracetam, two new SV2A ligands, improve paroxysmal dystonia in the dt sz mutant hamster.

  European journal of pharmacology 20081228

• Initial management of epilepsy.

  The New England journal of medicine 20081204

• Levetiracetam in newly diagnosed late-onset post-stroke seizures: a prospective observational study.

  Epilepsy research 20081201

• Effect of levetiracetam on cognitive functions and quality of life: a one-year follow-up study.

  Epileptic disorders : international epilepsy journal with videotape 20081201

• Optimal prevention of seizures induced by high-dose busulfan.

  Pharmacotherapy 20081201

• An unusual cause of collapse and neck pain.

  Emergency medicine journal : EMJ 20081201

• The role of the newer antiepileptic drugs in the treatment of generalized convulsive status epilepticus.

  Epilepsia 20081201

• [Follow-up study on levetiracetam monotherapy in children with epilepsy].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20081201

• Preemptive levetiracetam decreases postoperative pain in rats.

  Neuro endocrinology letters 20081201

• Effects of chronic treatment with levetiracetam on hippocampal field responses after pilocarpine-induced status epilepticus in rats.

  Brain research bulletin 20081125

• Quantification of levetiracetam in human plasma by liquid chromatography-tandem mass spectrometry: application to therapeutic drug monitoring.

  Journal of pharmaceutical and biomedical analysis 20081104

• The effects of levetiracetam on cognition: a non-interventional surveillance study.

  Epilepsy & behavior : E&B 20081101

• Levetiracetam in stiff-person syndrome.

  Journal of neurology 20081101

• Levetiracetam in absence epilepsy.

  Developmental medicine and child neurology 20081101

• Partial seizures and atypical absence seizures as a single ictal event in a patient with Lennox-Gastaut syndrome.

  Journal of child neurology 20081101

• [Non-convulsive epileptic status reverted with intravenous levetiracetam].

  Revista de neurologia 20081101

• Bioequivalence of two formulations of levetiracetam.

  International journal of clinical pharmacology and therapeutics 20081101

• Visualization of SV2A conformations in situ by the use of Protein Tomography.

  Biochemical and biophysical research communications 20081031

• Successful treatment of Holmes tremor by levetiracetam.

  Movement disorders : official journal of the Movement Disorder Society 20081030

• Antiemetic properties of the antiepileptic drug levetiracetam.

  The New England journal of medicine 20081023

• New antiepileptic drugs in pediatric epilepsy.

  Brain & development 20081001

• Cognitive fMRI and soluble telencephalin assessment in patients with localization-related epilepsy.

  Acta neurologica Scandinavica 20081001

• The efficacy and tolerability of Levetiracetam as an add-on therapy in patients with startle epilepsy.

  Seizure 20081001

• Levetiracetam prevents kindling-induced asymmetric accumulation of hippocampal 7S SNARE complexes.

  Epilepsia 20081001

• Levetiracetam monotherapy for late poststroke seizures in the elderly.

  Epilepsy & behavior : E&B 20081001

• Tolerability and dosing experience of intravenous levetiracetam in children and infants.

  Epilepsy research 20081001

• Positive and negative psychotropic effects of levetiracetam.

  Epilepsy & behavior : E&B 20081001

• Impending status epilepticus and anxiety in a pregnant woman treated with levetiracetam.

  Epilepsy & behavior : E&B 20081001

• Pyridoxine supplementation for the treatment of levetiracetam-induced behavior side effects in children: preliminary results.

  Epilepsy & behavior : E&B 20081001

• Levetiracetam versus phenytoin for seizure prophylaxis in severe traumatic brain injury.

  Neurosurgical focus 20081001

• Comparative cognitive effects of levetiracetam and topiramate in intractable epilepsy.

  Psychiatry and clinical neurosciences 20081001

• Treatment of seizures in a patient with Batten's disease.

  The Nurse practitioner 20081001

• Simple and validated HPLC-UV analysis of levetiracetam in deproteinized plasma of patients with epilepsy.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080915

• Effects of topiramate and levetiracetam vs placebo on habituation of contingent negative variation in migraine patients.

  Neuroscience letters 20080912

• Reporting and analysis of open-label extension studies of anti-epileptic drugs.

  Epilepsy research 20080901

• Efficacy and tolerability of levetiracetam versus phenytoin after supratentorial neurosurgery.

  Neurology 20080826

• Levetiracetam as a possible cause of fulminant liver failure.

  Neurology 20080826

• Antinociceptive efficacy of levetiracetam in a mice model for painful diabetic neuropathy.

  Acta anaesthesiologica Scandinavica 20080801

• Anti-convulsive and anti-epileptic properties of brivaracetam (ucb 34714), a high-affinity ligand for the synaptic vesicle protein, SV2A.

  British journal of pharmacology 20080801

• Early detection of behavioral side effects of antiepileptic treatment using handheld computers.

  Epilepsy & behavior : E&B 20080801

• Brivaracetam: a rational drug discovery success story.

  British journal of pharmacology 20080801

• Effect of levetiracetam on the postmastectomy pain syndrome.

  European journal of neurology 20080801

• Off-label use of antiepileptic drugs for the treatment of neonatal seizures.

  Pediatric neurology 20080801

• Levetiracetam in continuous spike waves during slow-wave sleep syndrome.

  Pediatric neurology 20080801

• Perspectives on interactions between antiepileptic drugs (AEDs) and antimicrobial agents.

  Epilepsia 20080801

• PKA-mediated phosphorylation is a novel mechanism for levetiracetam, an antiepileptic drug, activating ROMK1 channels.

  Biochemical pharmacology 20080715

• Add-on levetiracetam in children and adolescents with refractory epilepsy: results of an open-label multi-centre study.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20080701

• Development of tolerance to levetiracetam in rats with chronic epilepsy.

  Epilepsia 20080701

• Effects of uridine on kindling.

  Epilepsy & behavior : E&B 20080701

• Anticonvulsive and antiepileptogenic effects of levetiracetam in the audiogenic kindling model.

  Epilepsia 20080701

• Prolonged neurophysiologic effects of levetiracetam after oral administration in humans.

  Epilepsia 20080701

• Thrombocytopenia during levetiracetam therapy.

  Epilepsy research 20080701

• The risk of paradoxical levetiracetam effect is increased in mentally retarded patients.

  Epilepsia 20080701

• Levetiracetam for treatment of premenstrual dysphoric disorder: a pilot, open-label study.

  Archives of women's mental health 20080701

• Emesis responsive to levetiracetam.

  Journal of neurology, neurosurgery, and psychiatry 20080701

• Termination of absence status epilepticus by low-dose intravenous levetiracetam.

  Epilepsia 20080701

• Reversible panhypogammaglobulinemia associated with the antiepileptic agent levetiracetam.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20080701

• The efficacy and tolerability of levetiracetam in pharmacoresistant epileptic dogs.

  Veterinary journal (London, England : 1997) 20080601

• Implications of antiinflammatory properties of the anticonvulsant drug levetiracetam in astrocytes.

  Journal of neuroscience research 20080601

• Levetiracetam as monotherapy or add-on to valproate in the treatment of acute mania-a randomized open-label study.

  Psychopharmacology 20080601

• An in vivo [18F]MK-9470 microPET study of type 1 cannabinoid receptor binding in Wistar rats after chronic administration of valproate and levetiracetam.

  Neuropharmacology 20080601

• Intramuscular, intravenous and oral levetiracetam in dogs: safety and pharmacokinetics.

  Journal of veterinary pharmacology and therapeutics 20080601

• Activity, tolerability and efficacy of levetiracetam on cerebellar symptoms in multiple sclerosis patients: a pilot kinematic study.

  European journal of neurology 20080601

• Levetiracetam-associated hyponatremia.

  Seizure 20080601

• Tolerability and efficacy of oral loading of levetiracetam.

  Neurology 20080527

• Levetiracetam inhibits both ryanodine and IP3 receptor activated calcium induced calcium release in hippocampal neurons in culture.

  Neuroscience letters 20080516

• Intravenous levetiracetam in the treatment of benzodiazepine refractory status epilepticus.

  Journal of neurology, neurosurgery, and psychiatry 20080501

• Treatment of tardive dyskinesia with levetiracetam in a transplant patient.

  Acta neurologica Scandinavica 20080501

• Encephalopathy induced by levetiracetam added to valproate.

  Acta neurologica Scandinavica 20080501

• Clinical predictors in patients with refractory epilepsy exposed to levetiracetam: a single-center study.

  Acta neurologica Scandinavica 20080501

• Levetiracetam versus carbamazepine monotherapy for partial epilepsy in children less than 16 years of age.

  Journal of child neurology 20080501

• Effect of levetiracetam on cortical excitability: a transcranial magnetic stimulation study.

  European journal of neurology 20080501

• Should we accept the status quo? Time for new trials in status epilepticus.

  Journal of neurology, neurosurgery, and psychiatry 20080501

• Functional evaluation of polymorphisms in the human ABCB1 gene and the impact on clinical responses of antiepileptic drugs.

  Pharmacogenetics and genomics 20080501

• Efficacy of levetiracetam in children with epilepsy younger than 2 years of age.

  Journal of child neurology 20080501

• Use of propofol anesthesia and adjunctive treatment with levetiracetam and gabapentin in managing status epilepticus in a patient of acute intermittent porphyria.

  Epilepsia 20080501

• Induction of nuclear receptors and drug resistance in the brain microvascular endothelial cells treated with antiepileptic drugs.

  Current neurovascular research 20080501

• Seizure-freedom with combination therapy in localization-related epilepsy.

  Seizure 20080401

• High-field MRS study of GABA, glutamate and glutamine in social anxiety disorder: response to treatment with levetiracetam.

  Progress in neuro-psychopharmacology & biological psychiatry 20080401

• Effects of levetiracetam on EEG abnormalities in juvenile myoclonic epilepsy.

  Epilepsia 20080401

• Intravenous levetiracetam: treatment experience with the first 50 critically ill patients.

  Epilepsy & behavior : E&B 20080401

• Effects of levetiracetam on tardive dyskinesia: a randomized, double-blind, placebo-controlled study.

  The Journal of clinical psychiatry 20080401

• Clinical picture of EPM1-Unverricht-Lundborg disease.

  Epilepsia 20080401

• Synthesis and biological evaluation of novel dimiracetam derivatives useful for the treatment of neuropathic pain.

  Bioorganic & medicinal chemistry 20080315

• Levetiracetam as an adjunct to phenobarbital treatment in cats with suspected idiopathic epilepsy.

  Journal of the American Veterinary Medical Association 20080315

• HIF-1-regulated vasoactive systems are differentially involved in acute hypoxic stress responses of the developing brain of newborn mice and are not affected by levetiracetam.

  Brain research 20080314

• Translocation-positive acute myeloid leukemia associated with valproic acid therapy.

  Pediatric blood & cancer 20080301

• Long-term levetiracetam treatment affects reproductive endocrine function in female Wistar rats.

  Seizure 20080301

• Serum concentration/dose ratio of levetiracetam before, during and after pregnancy.

  Seizure 20080301

• The use of levetiracetam in a child with nonconvulsive status epilepticus.

  Journal of child neurology 20080301

• A pilot trial of levetiracetam in eyelid myoclonia with absences (Jeavons syndrome).

  Epilepsia 20080301

• Intravenous levetiracetam in children with epilepsy.

  Pediatric neurology 20080301

• Rapid dosage titration of levetiracetam in children.

  Pharmacotherapy 20080301

• Pharmaco-EEG-based assessment of interaction between ethanol and levetiracetam.

  Alcohol (Fayetteville, N.Y.) 20080301

• Levetiracetam for the treatment of idiopathic generalized epilepsy with myoclonic seizures.

  Neurology 20080219

• Effect of levetiracetam on depression and anxiety in adult epileptic patients.

  Progress in neuro-psychopharmacology & biological psychiatry 20080215

• Response of infantile spasms to levetiracetam.

  Neurology 20080212

• Dramatic weight loss with levetiracetam.

  Epilepsia 20080201

• Effects of levetiracetam as an add-on therapy on cognitive function and quality of life in patients with refractory partial seizures.

  Epilepsy & behavior : E&B 20080201

• Antiepileptic drugs and brain maturation: fetal exposure to lamotrigine generates cortical malformations in rats.

  Epilepsy research 20080201

• Levetiracetam in patients with impulsive aggression: a double-blind, placebo-controlled trial.

  The Journal of clinical psychiatry 20080201

• Levetiracetam has no acute effects on brain gamma-aminobutyric acid levels.

  Epilepsy & behavior : E&B 20080201

• Effect of levetiracetam on cardiac repolarization in healthy subjects: a single-dose, randomized, placebo- and active-controlled, four-way crossover study.

  Clinical therapeutics 20080201

• Levetiracetam for the treatment of hot flashes: a phase II study.

  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20080101

• Long-term effects of levetiracetam and topiramate in clinical practice: A head-to-head comparison.

  Seizure 20080101

• Levetiracetam monotherapy in juvenile myoclonic epilepsy.

  Seizure 20080101

• Levetiracetam in the treatment of antipsychotics-resistant Tourette syndrome.

  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20080101

• The effect of anticonvulsant drugs on the fibrinolytic activity of tissue plasminogen activator.

  Cerebrovascular diseases (Basel, Switzerland) 20080101

• Levetiracetam in juvenile myoclonic epilepsy: long-term efficacy in newly diagnosed adolescents.

  Developmental medicine and child neurology 20080101

• Exacerbations of seizures by levetiracetam.

  Epilepsia 20080101

• Sporadic multiple cerebral cavernomatosis: report of a case and review of literature.

  The neurologist 20080101

• Retrospective population pharmacokinetic analysis of levetiracetam in children and adolescents with epilepsy: dosing recommendations.

  Clinical pharmacokinetics 20080101

• Hemodiafiltration and high-flux hemodialysis significantly reduce serum valproate levels inducing epileptic seizures: case report.

  Blood purification 20080101

• Efficacy of levetiracetam in hemifacial spasm: a case report.

  Clinical neuropharmacology 20080101

• The effects of levetiracetam on alcohol consumption in alcohol-dependent subjects: an open label study.

  The American journal of drug and alcohol abuse 20080101

• [Levetiracetam and restless leg syndrome].

  Neurologia (Barcelona, Spain) 20080101

• Levetiracetam in patients with epilepsy and chronic liver disease: observations in a case series.

  Clinical neuropharmacology 20080101

• Treatment of juvenile myoclonic epilepsy.

  CNS neuroscience & therapeutics 20080101

• Levetiracetam for stiff-person syndrome: report of 2 patients.

  Clinical neuropharmacology 20080101

• Physiology-based simulations of a pathological condition: prediction of pharmacokinetics in patients with liver cirrhosis.

  Clinical pharmacokinetics 20080101

• Levetiracetam for the treatment of co-occurring alcohol dependence and anxiety: case series and review.

  The American journal of drug and alcohol abuse 20080101

• [The investigation of cataleptic muscle tonus changes in rats after audiogenic seizures].

  Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20080101

• [Use of keppra during the radiotherapy in patients with brain tumors and epileptic seizures after surgical treatment].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101

• Correlation of increase in phosphene threshold with reduction of migraine frequency: observation of levetiracetam-treated subjects.

  Headache 20080101

• Antiepileptic drugs in aneurysmal subarachnoid hemorrhage.

  Reviews in neurological diseases 20080101

• [Endocrine effects of antiepileptic drugs].

  Przeglad lekarski 20080101

• [The possibilities of using keppra (levetiracetam) in different neurological diseases].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101

• Are psychiatric adverse events of antiepileptic drugs a unique entity? A study on topiramate and levetiracetam.

  Epilepsia 20071201

• A pilot study transitioning children onto levetiracetam monotherapy to improve language dysfunction associated with benign rolandic epilepsy.

  Epilepsy & behavior : E&B 20071201

• The new antiepileptic drugs.

  Archives of disease in childhood. Education and practice edition 20071201

• [Use of levetiracetam in the management of post-anoxic myoclonias. A report of two cases].

  Neurologia (Barcelona, Spain) 20071201

• Switching from branded to generic antiepileptic drugs as a confounding factor and unpredictable diagnostic pitfall in epilepsy management.

  Epileptic disorders : international epilepsy journal with videotape 20071201

• Levetiracetam and bleeding disorders.

  Acta neurologica Belgica 20071201

• Neuropsychological and neurophysiologic effects of carbamazepine and levetiracetam.

  Neurology 20071127

• Long-term use of Levetiracetam in patients with severe childhood-onset epilepsy.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20071101

• Lack of pharmacokinetic interaction of levetiracetam on carbamazepine, valproic acid, topiramate, and lamotrigine in children with epilepsy.

  Epilepsia 20071101

• Adjunctive therapy of uncontrolled partial seizures with levetiracetam in Australian patients.

  Epilepsy & behavior : E&B 20071101

• Levetiracetam monotherapy in newly diagnosed cryptogenic West syndrome.

  Pediatric neurology 20071101

• [DRESS syndrome after carbamazepine].

  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20071101

• [The use of levetiracetam in monotherapy in post-stroke seizures in the elderly population].

  Revista de neurologia 20071101

• Levetiracetam.

  Drugs of today (Barcelona, Spain : 1998) 20071101

• Placebo-controlled study of levetiracetam in idiopathic generalized epilepsy.

  Neurology 20071030

• Orofacial dystonia related to Sjogren's syndrome.

  Clinical rheumatology 20071001

• Prolonged exposure to levetiracetam reveals a presynaptic effect on neurotransmission.

  Epilepsia 20071001

• The antiepileptic drug levetiracetam stabilizes the human epileptic GABAA receptors upon repetitive activation.

  Epilepsia 20071001

• Levetiracetam, phenytoin, and valproate act differently on rat bone mass, structure, and metabolism.

  Epilepsia 20071001

• Antiepileptic drug-induced neuronal cell death in the immature brain: effects of carbamazepine, topiramate, and levetiracetam as monotherapy versus polytherapy.

  The Journal of pharmacology and experimental therapeutics 20071001

• Effects of levetiracetam vs topiramate and placebo on visually evoked phase synchronization changes of alpha rhythm in migraine.

  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20071001

• Impact of levetiracetam on mood and cognition during prednisone therapy.

  European psychiatry : the journal of the Association of European Psychiatrists 20071001

• Levetiracetam monotherapy in Alzheimer patients with late-onset seizures: a prospective observational study.

  European journal of neurology 20071001

• Therapeutic drug monitoring of levetiracetam by high-performance liquid chromatography with photodiode array ultraviolet detection: preliminary observations on correlation between plasma concentration and clinical response in patients with refractory epilepsy.

  Therapeutic drug monitoring 20071001

• [Analysis of the cost-effectiveness of treatment for refractory partial epilepsy: a simulation model for pregabalin and levetiracetam].

  Revista de neurologia 20071001

• Drug monitoring: simultaneous analysis of lamotrigine, oxcarbazepine, 10-hydroxycarbazepine, and zonisamide by HPLC-UV and a rapid GC method using a nitrogen-phosphorus detector for levetiracetam.

  Journal of chromatographic science 20071001

• A double blind randomized placebo control trial of levetiracetam in Tourette syndrome.

  Movement disorders : official journal of the Movement Disorder Society 20070915

• Retrospective analysis of the efficacy and tolerability of levetiracetam in patients with metastatic brain tumors.

  Journal of neuro-oncology 20070901

• Current treatment of myoclonic astatic epilepsy: clinical experience at the Children's Hospital of Philadelphia.

  Epilepsia 20070901

• Accidental overdosage of levetiracetam in two children caused no side effects.

  Epilepsy & behavior : E&B 20070901

• Modeling and simulation of intravenous levetiracetam pharmacokinetic profiles in children to evaluate dose adaptation rules.

  Epilepsy research 20070901

• [Levetiracetam in the treatment of epilepsy in adults. Experience with monotherapy].

  Revista de neurologia 20070901

• [Effect of levetiracetam on the sodium currents of rat hippocampal neurons exposed to coriaria lactone].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20070901

• Comparison of levetiracetam and controlled-release carbamazepine in newly diagnosed epilepsy.

  Neurology 20070828

• An open trial of levetiracetam for segmental and generalized dystonia.

  Movement disorders : official journal of the Movement Disorder Society 20070815

• Tuberous sclerosis successfully treated with levetiracetam monotherapy: 18 months of follow-up.

  Pharmacy world & science : PWS 20070801

• Suicidal ideation in epilepsy and levetiracetam therapy.

  Epilepsy & behavior : E&B 20070801

• Prophylactic treatment with levetiracetam after status epilepticus: lack of effect on epileptogenesis, neuronal damage, and behavioral alterations in rats.

  Neuropharmacology 20070801

• Levetiracetam for manic behavior in hospitalized geriatric patients with dementia of the Alzheimer's type.

  Journal of clinical psychopharmacology 20070801

• [Effectiveness and safety of levetiracetam in patients with essential tremor: data from an open 11-week follow-up trial].

  Revista de neurologia 20070801

• The SKATE study: an open-label community-based study of levetiracetam as add-on therapy for adults with uncontrolled partial epilepsy.

  Epilepsy research 20070801

• An open-label trial of levetiracetam in severe myoclonic epilepsy of infancy.

  Neurology 20070717

• [Probable levetiracetam-induced psychosis].

  Medicina clinica 20070714

• Efficacy and safety of levetiracetam as adjunctive treatment of refractory partial seizures in a multicentre open-label single-arm trial in Korean patients.

  Seizure 20070701

• Levetiracetam for the treatment of epilepsy among adults with intellectual disabilities.

  Journal of intellectual disability research : JIDR 20070701

• Influence of levetiracetam on the anticonvulsant efficacy of conventional antiepileptic drugs against audiogenic seizures in DBA/2 mice.

  Epilepsy research 20070701

• Effect of age and comedication on levetiracetam pharmacokinetics and tolerability.

  Epilepsia 20070701

• Levetiracetam attenuates spontaneous spike-and-wave discharges in DBA/2J mice.

  Epilepsy research 20070701

• Levetiracetam as adjunctive therapy for refractory anxiety disorders.

  The Journal of clinical psychiatry 20070701

• Coexistence of epileptic nocturnal wanderings and an arachnoid cyst.

  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20070615

• Effect of levetiracetam on molecular regulation of hippocampal glutamate and GABA transporters in rats with chronic seizures induced by amygdalar FeCl3 injection.

  Brain research 20070602

• Levetiracetam or oxcarbazepine as monotherapy in newly diagnosed benign epilepsy of childhood with centrotemporal spikes (BECTS): an open-label, parallel group trial.

  Brain & development 20070601

• Levetiracetam in three cases of progressive myoclonus epilepsy.

  Pharmacy world & science : PWS 20070601

• Efficacy and safety of levetiracetam in infants and young children with refractory epilepsy.

  Seizure 20070601

• Pharmacokinetics of levetiracetam during pregnancy, delivery, in the neonatal period, and lactation.

  Epilepsia 20070601

• The effect of levetiracetam in startle disease.

  Journal of neurology 20070601

• Efficacy and tolerability of levetiracetam in children younger than 4 years: a retrospective review.

  Epilepsia 20070601

• Pharmacokinetics of levetiracetam in infants and young children with epilepsy.

  Epilepsia 20070601

• Juvenile myoclonic epilepsy: a benign disorder? Personality traits and psychiatric symptoms.

  Epilepsy & behavior : E&B 20070601

• Status gelasticus associated with levetiracetam as add-on treatment.

  Epileptic disorders : international epilepsy journal with videotape 20070601

• Saliva and serum levetiracetam concentrations in patients with epilepsy.

  Therapeutic drug monitoring 20070601

• Effects of levetiracetam in lipid peroxidation level, nitrite-nitrate formation and antioxidant enzymatic activity in mice brain after pilocarpine-induced seizures.

  Cellular and molecular neurobiology 20070501

• Single-dose pharmacokinetics of levetiracetam in healthy Chinese male subjects.

  British journal of clinical pharmacology 20070501

• The influence of antiepileptic drugs on cognition: a comparison of levetiracetam with topiramate.

  Epilepsy & behavior : E&B 20070501

• The safety of levetiracetam.

  Expert opinion on drug safety 20070501

• Levetiracetam-induced diffuse interstitial lung disease.

  Journal of child neurology 20070501

• Levetiracetam in nonconvulsive status epilepticus in childhood: a case report.

  Journal of child neurology 20070501

• Levetiracetam monotherapy for children and adolescents with benign rolandic seizures.

  Seizure 20070401

• Prospective assessment of levetiracetam pharmacokinetics during dose escalation in 4- to 12-year-old children with partial-onset seizures on concomitant carbamazepine or valproate.

  Epilepsy research 20070401

• Modulation of AMPA receptors in cultured cortical neurons induced by the antiepileptic drug levetiracetam.

  Epilepsia 20070401

• Levetiracetam and felbamate interact both pharmacodynamically and pharmacokinetically: an isobolographic analysis in the mouse maximal electroshock model.

  Epilepsia 20070401

• Dramatic response to levetiracetam in post-ischaemic Holmes' tremor.

  Journal of neurology, neurosurgery, and psychiatry 20070401

• Adjuvant levetiracetam in adolescent mania.

  Journal of clinical psychopharmacology 20070401

• Levetiracetam monotherapy in children with epilepsy.

  Pediatric neurology 20070401

• [Efficacy and safety of levetiracetam (keppra) add-on treatment in adult patients with refractory epilepsy in two tertiary centers].

  Harefuah 20070401

• Role of intravenous levetiracetam in status migrainosus.

  The journal of headache and pain 20070401

• No kinetic interaction between levetiracetam and cyclosporine: a case report.

  Journal of child neurology 20070401

• MERRF syndrome without ragged-red fibers: the need for molecular diagnosis.

  Biochemical and biophysical research communications 20070323

• Levetiracetam as a treatment option in non-convulsive status epilepticus.

  Epilepsy research 20070301

• Dose-response population analysis of levetiracetam add-on treatment in refractory epileptic patients with partial onset seizures.

  Epilepsy research 20070301

• Retention rate of levetiracetam in children with intractable epilepsy at 1 year.

  Seizure 20070301

• Anticonvulsants in sports: ethical considerations.

  Epilepsy & behavior : E&B 20070301

• Levetiracetam in clinical practice: long-term experience in patients with refractory epilepsy referred to a tertiary epilepsy center.

  Epilepsy & behavior : E&B 20070301

• Levetiracetam intravenous infusion as an alternative to oral dosing in patients with partial-onset seizures.

  Epilepsia 20070301

• Psychic disturbances associated with sodium valproate plus levetiracetam.

  The Annals of pharmacotherapy 20070301

• Levetiracetam prophylaxis in pediatric migraine--an open-label study.

  Headache 20070301

• Comparison of levetiracetam and controlled-release carbamazepine in newly diagnosed epilepsy.

  Neurology 20070206

• Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein.

  Neuropharmacology 20070201

• Administration of levetiracetam after prolonged status epilepticus does not protect from mitochondrial dysfunction in a rodent model.

  Epilepsy research 20070201

• [A new aspect in the research on antiepileptic drugs].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20070201

• [Epilepsy in the elderly].

  Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20070201

• [Clinical experience with levetiracetam for adults with epilepsy].

  Ideggyogyaszati szemle 20070120

• Determination of levetiracetam in human plasma/serum/saliva by liquid chromatography-electrospray tandem mass spectrometry.

  Clinica chimica acta; international journal of clinical chemistry 20070101

• Effect of levetiracetam on visual-spatial memory following status epilepticus.

  Epilepsy research 20070101

• Novel anticonvulsant drugs.

  Pharmacology & therapeutics 20070101

• Zonisamide or levetiracetam for adults with cyclic vomiting syndrome: a case series.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20070101

• Levetiracetam reduces anesthetic-induced hyperalgesia in rats.

  Anesthesia and analgesia 20070101

• Comparison of plasma and saliva concentrations of levetiracetam following administration orally as a tablet and as a solution in healthy adult volunteers.

  International journal of clinical pharmacology and therapeutics 20070101

• Developmental toxic effects of N-ethyl-2-pyrrolidone administered orally to rats.

  Journal of applied toxicology : JAT 20070101

• Kinetic-dynamic monitoring of levetiracetam effects in patients with Parkinson disease and levodopa-induced dyskinesias.

  Clinical neuropharmacology 20070101

• Levetiracetam: the profile of a novel anticonvulsant drug-part I: preclinical data.

  CNS drug reviews 20070101

• Levetiracetam: part II, the clinical profile of a novel anticonvulsant drug.

  CNS drug reviews 20070101

• Refractory seizures associated with an organic aciduria in a dog.

  Journal of the American Animal Hospital Association 20070101

• Population pharmacokinetics of levetiracetam in Japanese and Western adults.

  Clinical pharmacokinetics 20070101

• [Neuronal and neurochemical mechanisms underlying the effect of a novel antiepileptic drug levetiracetam].

  Eksperimental'naia i klinicheskaia farmakologiia 20070101

• Levetiracetam use in critically ill patients.

  Neurocritical care 20070101

• Levetiracetam for the treatment of neonatal seizures.

  Journal of child neurology 20070101

• [Open-label, prospective and observational study of efficacy and tolerability with levetiracetam during one year of follow-up].

  Neurologia (Barcelona, Spain) 20070101

• [New antiepileptics in development].

  Pharmazie in unserer Zeit 20070101

• IV levetiracetam in the management of non-convulsive status epilepticus.

  Neurocritical care 20070101

• Brivaracetam is superior to levetiracetam in a rat model of post-hypoxic myoclonus.

  Journal of neural transmission (Vienna, Austria : 1996) 20070101

• Comparison of motor activity and sleep in patients with complex partial seizures on levetiracetam treatment and a group of healthy subjects.

  Behavioural neurology 20070101

• Levetiracetam-responding paroxysmal nonkinesigenic dyskinesia.

  Clinical neuropharmacology 20070101

• Neurodevelopmental impact of antiepileptic drugs and seizures in the immature brain.

  Epilepsia 20070101

• Nonepileptic hallucinations in use of levetiracetam.

  Psychosomatics 20070101

• Levetiracetam is not effective for essential tremor.

  Clinical neuropharmacology 20070101

• [Anticonvulsant effects of levetiracetam on audiogenic epileptiform siezures in Krushinsky-Molodkina rats].

  Eksperimental'naia i klinicheskaia farmakologiia 20070101

• Clinical pharmacology of parenteral use of antiepileptic drugs.

  Epilepsia 20070101

• The use of valproate and new antiepileptic drugs in status epilepticus.

  Epilepsia 20070101

• Intensive care unit management of patients with status epilepticus.

  Epilepsia 20070101

• [Dynamics of clinical, neurophysiological and radiological indices as a criterion for evaluation of treatment quality of symptomatic epilepsy with keppra and topamax].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20070101

• [Levetiracetam (keppra) in epileptology].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20070101

• Levetiracetam (keppra) in the treatment of refractory status epilepticus.

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20070101

• The actions of lamotrigine and levetiracetam on the conduction properties of isolated rat sciatic nerve.

  European journal of pharmacology 20061228

• Long-term levetiracetam treatment of epilepsy patients: clinical audit.

  Epilepsy research 20061201

• Influence of levetiracetame on ictal and postictal EEG in patients with partial seizures.

  European journal of neurology 20061201

• [Diagnosis and treatment in a case of respiratory myoclonus].

  Revista de neurologia 20061201

• Use of levetiracetam in hospitalized patients.

  Epilepsia 20061201

• Enantiomeric impurity determination of levetiracetam using capillary electrochromatography.

  Journal of separation science 20061201

• Levetiracetam in pregnancy: preliminary experience from the UK Epilepsy and Pregnancy Register.

  Neurology 20061128

• Open-label pilot study of levetiracetam (Keppra) for the treatment of chorea in Huntington's disease.

  Movement disorders : official journal of the Movement Disorder Society 20061101

• Neuropsychological and psychiatric impact of add-on titration of pregabalin versus levetiracetam: a comparative short-term study.

  Epilepsy & behavior : E&B 20061101

• Disfluent speech in patients with partial epilepsy: beneficial effect of levetiracetam.

  Epilepsy & behavior : E&B 20061101

• Levetiracetam versus placebo in childhood and adolescent autism: a double-blind placebo-controlled study.

  International clinical psychopharmacology 20061101

• The use of levetiracetam to decrease mania in elderly bipolar patients.

  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20061101

• In situ metabolism of levetiracetam in blood of patients with epilepsy.

  Epilepsia 20061101

• Clinical development of levetiracetam for amyotrophic lateral sclerosis.

  Drug news & perspectives 20061101

• Levetiracetam therapy in patients with brain tumour and epilepsy.

  Journal of neuro-oncology 20061001

• [Effectiveness and safety of levetiracetam in 133 children with medication resistant epileptic seizures].

  Revista de neurologia 20061001

• Safety and efficacy of levetiracetam for patients with panic disorder: results of an open-label, fixed-flexible dose study.

  The Journal of clinical psychiatry 20061001

• In vivo characterisation of the small-conductance KCa (SK) channel activator 1-ethyl-2-benzimidazolinone (1-EBIO) as a potential anticonvulsant.

  European journal of pharmacology 20060928

• Predicting drug-resistant patients who respond to add-on therapy with levetiracetam.

  Seizure 20060901

• The role of hippocampal sclerosis in antiepileptic drug-related depression in patients with epilepsy: a study on levetiracetam.

  Seizure 20060901

• Open label, long-term, pragmatic study on levetiracetam in the treatment of juvenile myoclonic epilepsy.

  Epilepsy research 20060901

• Levetiracetam reduces frequency and duration of epileptic activity in patients with refractory primary generalized epilepsy.

  Seizure 20060901

• Update on treatment of epilepsy in people with intellectual disabilities.

  Current opinion in psychiatry 20060901

• Efficacy and safety of levetiracetam in clinical practice: results of the SKATE trial from Belgium and The Netherlands.

  Seizure 20060901

• Levetiracetam: a long-term follow-up study of efficacy and safety.

  Acta neurologica Scandinavica 20060901

• Assessment of a dose-response relationship of levetiracetam.

  European journal of neurology 20060901

• Comparison of reproductive effects of levetiracetam and valproate studied in prepubertal porcine ovarian follicular cells.

  Epilepsia 20060901

• Levetiracetam-induced myoclonic status epilepticus in myoclonic-astatic epilepsy: a case report.

  Epileptic disorders : international epilepsy journal with videotape 20060901

• Levetiracetam in tardive dyskinesia: an open label study.

  Movement disorders : official journal of the Movement Disorder Society 20060801

• Levetiracetam in Meige's syndrome.

  Acta neurologica Scandinavica 20060701

• Levetiracetam intravenous infusion: a randomized, placebo-controlled safety and pharmacokinetic study.

  Epilepsia 20060701

• Neocortical hyperexcitability in a genetic model of absence seizures and its reduction by levetiracetam.

  Epilepsia 20060701

• Levetiracetam-induced depression in a healthy adult.

  The Journal of clinical psychiatry 20060701

• Double-blind placebo-controlled trial of adjunctive levetiracetam in pediatric partial seizures.

  Neurology 20060613

• Levetiracetam suppresses long-loop reflexes at the cortical level.

  Muscle & nerve 20060601

• Levetiracetam in a broad population of patients with refractory epilepsy: interim results of the international SKATE trial.

  Acta neurologica Scandinavica 20060601

• Levetiracetam for cerebellar tremor in multiple sclerosis: an open-label pilot tolerability and efficacy study.

  Journal of neurology 20060601

• Levetiracetam for the treatment of alcohol withdrawal syndrome: an open-label pilot trial.

  Journal of clinical psychopharmacology 20060601

• [The value of an oral solution of levetiracetam in status epilepticus].

  Revista de neurologia 20060601

• Measurement of seizure freedom in adjunctive therapy studies in refractory partial epilepsy: the levetiracetam experience.

  Epileptic disorders : international epilepsy journal with videotape 20060601

• Levetiracetam pharmacokinetics in neonates at birth.

  Epilepsia 20060601

• Neuromodulation with levetiracetam and vagus nerve stimulation in experimental animal models of epilepsy.

  Acta neurologica Belgica 20060601

• [Experience with levetiracetam in childhood epilepsy].

  Ideggyogyaszati szemle 20060520

• The impact of levetiracetam on challenging behavior.

  Epilepsy & behavior : E&B 20060501

• Determinants of success in the use of oral levetiracetam in status epilepticus.

  Epilepsy & behavior : E&B 20060501

• Retrospective analysis of the efficacy and tolerability of levetiracetam in brain tumor patients.

  Journal of neuro-oncology 20060501

• An open-label trial of levetiracetam for treatment of cervical dystonia.

  Movement disorders : official journal of the Movement Disorder Society 20060501

• Single-dose bioavailability of levetiracetam intravenous infusion relative to oral tablets and multiple-dose pharmacokinetics and tolerability of levetiracetam intravenous infusion compared with placebo in healthy subjects.

  Clinical therapeutics 20060501

• Binding characteristics of levetiracetam to synaptic vesicle protein 2A (SV2A) in human brain and in CHO cells expressing the human recombinant protein.

  European journal of pharmacology 20060424

• Antimyoclonic effect of levetiracetam in MERRF syndrome.

  Journal of the neurological sciences 20060415

• Specific effect of levetiracetam in experimental human pain models.

  European journal of pain (London, England) 20060401

• Levetiracetam in patients with generalised epilepsy and myoclonic seizures: an open label study.

  Seizure 20060401

• The use of levetiracetam in refractory status epilepticus.

  Seizure 20060401

• Levetiracetam can be effective in the treatment of restless legs syndrome with periodic limb movements in sleep: report of two cases.

  Journal of neurology, neurosurgery, and psychiatry 20060401

• Treatment of neuroleptic-induced tardive dyskinesia with levetiracetam: a case series.

  Journal of clinical psychopharmacology 20060401

• Language-induced epilepsy, acquired stuttering, and idiopathic generalized epilepsy: phenotypic study of one family.

  Epilepsia 20060401

• Levetiracetam: an improvement of attention and of oral fluency in patients with partial epilepsy.

  Epilepsy research 20060301

• Evidence for a rapid action of levetiracetam compared to topiramate in refractory partial epilepsy.

  Seizure 20060301

• Levetiracetam: antiepileptic properties and protective effects on mitochondrial dysfunction in experimental status epilepticus.

  Epilepsia 20060301

• Onset of action of levetiracetam: a RCT trial using therapeutic intensive seizure analysis (TISA).

  Epilepsia 20060301

• Identifying baseline characteristics of placebo responders versus nonresponders in randomized double-blind trials of refractory partial-onset seizures.

  Epileptic disorders : international epilepsy journal with videotape 20060301

• Effect of levetiracetam on truncal tic in neuroacanthocytosis.

  Acta neurologica Taiwanica 20060301

• Effects of intermittent levetiracetam dosing in a patient with refractory daily seizures.

  Neurology 20060227

• Catatonia induced by levetiracetam.

  Epilepsy & behavior : E&B 20060201

• Use of levetiracetam in treating epilepsy associated with other medical conditions.

  Acta neurologica Scandinavica 20060201

• Post-anoxic myoclonus: a case presentation and review of management in the rehabilitation setting.

  Brain injury 20060201

• Nonconvulsive status epilepticus due to ifosfamide.

  The Annals of pharmacotherapy 20060201

• Levetiracetam for treatment-refractory posttraumatic stress disorder.

  The Journal of clinical psychiatry 20060201

• Treatment of chorea with levetiracetam.

  European journal of clinical pharmacology 20060101

• The long term retention of levetiracetam in a large cohort of patients with epilepsy.

  Journal of neurology, neurosurgery, and psychiatry 20060101

• Cortical laminar necrosis related to prolonged focal status epilepticus.

  Journal of neurology, neurosurgery, and psychiatry 20060101

• Levetiracetam in a neonate with malignant migrating partial seizures.

  Pediatric neurology 20060101

• Pharmacodynamic and pharmacokinetic characterization of interactions between levetiracetam and numerous antiepileptic drugs in the mouse maximal electroshock seizure model: an isobolographic analysis.

  Epilepsia 20060101

• Efficacy and safety of levetiracetam (up to 2000 mg/day) in Taiwanese patients with refractory partial seizures: a multicenter, randomized, double-blind, placebo-controlled study.

  Epilepsia 20060101

• Effects of levetiracetam on nocturnal sleep and daytime vigilance in healthy volunteers.

  Epilepsia 20060101

• Levetiracetam as adjunctive antiepileptic therapy for patients with tuberous sclerosis complex: a retrospective open-label trial.

  Journal of child neurology 20060101

• Drug monitoring and toxicology: a procedure for the monitoring of levetiracetam and zonisamide by HPLC-UV.

  Journal of analytical toxicology 20060101

• Efficacy and tolerability of levetiracetam in Parkinson disease patients with levodopa-induced dyskinesia.

  Clinical neuropharmacology 20060101

• A new frontier in epilepsy: novel antiepileptogenic drugs.

  Journal of pharmacological sciences 20060101

• Determination of levetiracetam in human plasma by liquid chromatography/electrospray tandem mass spectrometry and its application to bioequivalence studies.

  Rapid communications in mass spectrometry : RCM 20060101

• [Fulminant liver failure in a patient on carbamazepine and levetiracetam treatment associated with status epilepticus].

  Archiv fur Kriminologie 20060101

• [The results of the two-year experience of using keppra in therapy of adult patients with epilepsy].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101

• Levetiracetam is neuroprotective in murine models of closed head injury and subarachnoid hemorrhage.

  Neurocritical care 20060101

• Levetiracetam in tardive dyskinesia.

  Clinical neuropharmacology 20060101

• Pharmacokinetic variability of newer antiepileptic drugs: when is monitoring needed?

  Clinical pharmacokinetics 20060101

• Antiepileptic treatment in paediatric oncology--an interdisciplinary challenge.

  Klinische Padiatrie 20060101

• Levetiracetam-induced Parkinsonism in a Huntington disease patient.

  Clinical neuropharmacology 20060101

• Levetiracetam in the prophylaxis of migraine with aura: a 6-month open-label study.

  Clinical neuropharmacology 20060101

• The Effect of Antiepileptic Drugs on Cognition: Patient Perceived Cognitive Problems of Topiramate versus Levetiracetam in Clinical Practice.

  Epilepsia 20060101

• Potential of levetiracetam in mood disorders: a preliminary review.

  CNS drugs 20060101

• Levetiracetam in idiopathic generalised epilepsy and porphyria cutanea tarda.

  Clinical drug investigation 20060101

• Hyponatremia from oxcarbazepine and carbamazepine.

  Neurology 20051227

• Levetiracetam selectively potentiates the acute neurotoxic effects of topiramate and carbamazepine in the rotarod test in mice.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20051201

• Levetiracetam in patients with cortical myoclonus: a clinical and electrophysiological study.

  Movement disorders : official journal of the Movement Disorder Society 20051201

• Antiepileptic drugs and neuroprotection: current status and future roles.

  Epilepsy & behavior : E&B 20051201

• Long-term efficacy of levetiracetam for partial seizures.

  Seizure 20051201

• Rapid kindling in preclinical anti-epileptic drug development: the effect of levetiracetam.

  Epilepsy research 20051201

• Levetiracetam efficacy in epileptic syndromes with continuous spikes and waves during slow sleep: experience in 12 cases.

  Epilepsia 20051201

• Re: Drug-induced psychosis with levetiracetam.

  Canadian journal of psychiatry. Revue canadienne de psychiatrie 20051201

• Levetiracetam for the treatment of generalized dystonia.

  Parkinsonism & related disorders 20051101

• Effects of levetiracetam on sleep in normal volunteers.

  Epilepsy & behavior : E&B 20051101

• Levetiracetam for mood stabilization and maintenance of seizure control following multiple treatment failures.

  The Annals of pharmacotherapy 20051101

• Levetiracetam in patients with refractory epilepsy: results of the SKATE trial in Austria, Germany and Switzerland.

  Seizure 20051001

• Levetiracetam in children with refractory epilepsy: a multicenter open label study in Germany.

  Seizure 20051001

• Effects of Nefiracetam, a novel pyrrolidone-type nootropic agent, on the amygdala-kindled seizures in rats.

  Epilepsia 20051001

• [The value of levetiracetam in epileptic status].

  Revista de neurologia 20051001

• Characterization of [(3)H]ucb 30889 binding to synaptic vesicle protein 2A in the rat spinal cord.

  European journal of pharmacology 20050927

• Evaluation of levetiracetam effects on pilocarpine-induced seizures: cholinergic muscarinic system involvement.

  Neuroscience letters 20050916

• Open-label pilot study of levetiracetam (Keppra) for the treatment of levodopa-induced dyskinesias in Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20050901

• An audit of lamotrigine, levetiracetam and topiramate usage for epilepsy in a district general hospital.

  Seizure 20050901

• Chronic levetiracetam treatment early in life decreases epileptiform events in young GAERS, but does not prevent the expression of spike and wave discharges during adulthood.

  Seizure 20050901

• Long-lasting antiepileptic effects of levetiracetam against epileptic seizures in the spontaneously epileptic rat (SER): differentiation of levetiracetam from conventional antiepileptic drugs.

  Epilepsia 20050901

• Clinical experience with levetiracetam in idiopathic generalized epilepsy according to different syndrome subtypes.

  Epileptic disorders : international epilepsy journal with videotape 20050901

• Levetiracetam in social phobia: a placebo controlled pilot study.

  Journal of psychopharmacology (Oxford, England) 20050901

• Effects of anticonvulsants on soman-induced epileptiform activity in the guinea-pig in vitro hippocampus.

  European journal of pharmacology 20050822

• The effect of levetiracetam on levodopa induced dyskinesia in patients with Parkinson's disease.

  Parkinsonism & related disorders 20050801

• Separation of antiepileptogenic and antiseizure effects of levetiracetam in the spontaneously epileptic rat (SER).

  Epilepsia 20050801

• Fast and sustained efficacy of levetiracetam during titration and the first 3 months of treatment in refractory epilepsy.

  Epilepsia 20050801

• Efficacy of levetiracetam at 12 months in children classified by seizure type, cognitive status, and previous anticonvulsant drug use.

  Journal of child neurology 20050701

• Broad-spectrum efficacy of zonisamide at 12 months in children with intractable epilepsy.

  Journal of child neurology 20050701

• Use of levetiracetam to treat tics in children and adolescents with Tourette syndrome.

  Movement disorders : official journal of the Movement Disorder Society 20050601

• Effects of levetiracetam on the production of nitric oxide--an in vivo study.

  Journal of neurology 20050601

• Chorea in a patient with cerebral palsy: treatment with levetiracetam.

  Movement disorders : official journal of the Movement Disorder Society 20050601

• Pharmacological and histological characterisation of nicotine-kindled seizures in mice.

  Neuropharmacology 20050601

• Sulthiame but not levetiracetam exerts neurotoxic effect in the developing rat brain.

  Experimental neurology 20050601

• Nonconvulsive status epilepticus on treatment with levetiracetam.

  Epilepsy & behavior : E&B 20050601

• Efficacy and safety of levetiracetam: an add-on trial in children with refractory epilepsy.

  Seizure 20050601

• Anticonvulsant properties of the novel nootropic agent nefiracetam in seizure models of mice and rats.

  Epilepsia 20050601

• Hyponatremia associated with repeated use of levetiracetam.

  Epilepsia 20050601

• Pharmacokinetics of levetiracetam in patients with moderate to severe liver cirrhosis (Child-Pugh classes A, B, and C): characterization by dynamic liver function tests.

  Clinical pharmacology and therapeutics 20050601

• Prediction of genotoxicity of chemical compounds by statistical learning methods.

  Chemical research in toxicology 20050601

• Levetiracetam for agitated Alzheimer's disease patients.

  International psychogeriatrics 20050601

• Therapeutic approach in a case of Pearson's syndrome.

  Minerva pediatrica 20050601

• Determination of levetiracetam in human plasma with minimal sample pretreatment.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050505

• The antiepileptic drug levetiracetam decreases the inositol 1,4,5-trisphosphate-dependent [Ca2+]I increase induced by ATP and bradykinin in PC12 cells.

  The Journal of pharmacology and experimental therapeutics 20050501

• Levetiracetam for the treatment of essential tremor.

  Movement disorders : official journal of the Movement Disorder Society 20050501

• Ketter's hypothesis of the mood effects of antiepileptic drugs coupled to the mechanism of action of topiramate and levetiracetam.

  Epilepsy & behavior : E&B 20050501

• Levetiracetam concentrations in serum and in breast milk at birth and during lactation.

  Epilepsia 20050501

• Optimal seizure management in brain tumor patients.

  Current neurology and neuroscience reports 20050501

• Migraine preventive therapy: current and emerging treatment options.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20050501

• Oral absorption kinetics of levetiracetam: the effect of mixing with food or enteral nutrition formulas.

  Clinical therapeutics 20050501

• Hypersomnia in an epilepsy patient treated with levetiracetam.

  Epilepsia 20050401

• The effect of levetiracetam on essential tremor.

  Neurology 20050322

• Levetiracetam for seizures after liver transplantation.

  Neurology 20050322

• Clinical experience of levetiracetam monotherapy for adults with epilepsy: 1-year follow-up study.

  Seizure 20050301

• Limited efficacy of levetiracetam on myoclonus of different etiologies.

  Parkinsonism & related disorders 20050301

• Preliminary observations on the effectiveness of levetiracetam in the open adjunctive treatment of refractory bipolar disorder.

  The Journal of clinical psychiatry 20050301

• Continued use of zonisamide following development of renal calculi.

  Neurology 20050222

• Rapid onset of action of levetiracetam in refractory epilepsy patients.

  Epilepsia 20050201

• Levetiracetam in pediatrics.

  Journal of child neurology 20050201

• Levetiracetam in the treatment of vascular chorea: a case report.

  European journal of clinical pharmacology 20050101

• Levetiracetam in refractory epilepsy: a prospective observational study.

  Seizure 20050101

• Clinical experience with levetiracetam in childhood epilepsy: an add-on and mono-therapy trial.

  Seizure 20050101

• Levetiracetam in the treatment of infantile spasms.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20050101

• [Keppra in epilepsy treatment: efficacy and tolerability].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101

• Efficacy and safety of levetiracetam 1000-3000 mg/day in patients with refractory partial-onset seizures: a multicenter, open-label single-arm study.

  Epilepsy research 20050101

• Levetiracetam induced polyneuropathy: a case report.

  Electromyography and clinical neurophysiology 20050101

• Meta-analysis and indirect comparisons of levetiracetam with other second-generation antiepileptic drugs in partial epilepsy.

  Clinical neuropharmacology 20050101

• Levetiracetam in L-dopa-induced dyskinesia.

  Clinical neuropharmacology 20050101

• Levetiracetam use and pregnancy outcome.

  Reproductive toxicology (Elmsford, N.Y.) 20050101

• Levetiracetam as an adjunctive analgesic in neoplastic plexopathies: case series and commentary.

  Journal of pain & palliative care pharmacotherapy 20050101

• Effect of levetiracetam on the pharmacokinetics of adjunctive antiepileptic drugs: a pooled analysis of data from randomized clinical trials.

  Epilepsy research 20050101

• Economic evaluation of levetiracetam as an add-on therapy in patients with refractory epilepsy.

  PharmacoEconomics 20050101

• Efficacy and tolerability of levetiracetam treatment in an epileptic patient with SLE.

  The Annals of pharmacotherapy 20050101

• Levetiracetam-induced parkinsonism in a Huntington disease patient.

  Clinical neuropharmacology 20050101

• Levetiracetam in the treatment of status epilepticus in adults: a study of 13 episodes.

  European neurology 20050101

• [Efficacy of keppra in combined therapy in pharmacoresistant adult epilepsy patients].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101

• Neuroprotection possibilities in epileptic children.

  Roczniki Akademii Medycznej w Bialymstoku (1995) 20050101

• Benefit-risk assessment of levetiracetam in the treatment of partial seizures.

  Drug safety 20050101

• New antiepileptic drugs in practice--how do they perform in the real world?

  Acta neurologica Scandinavica. Supplementum 20050101

• Antiepileptic drug discovery: lessons from the past and future challenges.

  Acta neurologica Scandinavica. Supplementum 20050101

• Levetiracetam in porphyric status epilepticus: a case report.

  Clinical neuropharmacology 20050101

• Idiopathic generalized epilepsies: a review and modern approach.

  Epilepsia 20050101

• Levetiracetam in the treatment of idiopathic generalized epilepsies.

  Epilepsia 20050101

• Efficacy of levetiracetam in Huntington disease.

  Clinical neuropharmacology 20050101

• Profile of anticonvulsant activity and neuroprotective effects of novel and potential antiepileptic drugs--an update.

  Pharmacological reports : PR 20050101

• How significant is the difference between drug doses influencing the threshold for electroconvulsions?

  Pharmacological reports : PR 20050101

• Substantial improvement in a Meige's syndrome patient with levetiracetam treatment.

  Movement disorders : official journal of the Movement Disorder Society 20041201

• Effects of levetiracetam on spike and wave discharges in WAG/Rij rats.

  Seizure 20041201

• Levetiracetam for people with mental retardation and refractory epilepsy.

  Epilepsy & behavior : E&B 20041201

• Monotherapy treatment of bipolar disorder with levetiracetam.

  Epilepsy & behavior : E&B 20041201

• Levetiracetam in the management of epilepsy.

  Hospital medicine (London, England : 1998) 20041201

• Drug-induced psychosis after long-term treatment with levetiracetam.

  Canadian journal of psychiatry. Revue canadienne de psychiatrie 20041201

• Retrospective study of the use of levetiracetam in childhood seizure disorders.

  Journal of child neurology 20041201

• Clinical, cognitive, and neurophysiologic correlates of short-term treatment with carbamazepine, oxcarbazepine, and levetiracetam in healthy volunteers.

  The Annals of pharmacotherapy 20041101

• Acute repetitive pilomotor seizures (goose bumps) in a patient with right mesial temporal sclerosis.

  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20041101

• Levetiracetam influences human motor cortex excitability mainly by modulation of ion channel function--a TMS study.

  Epilepsy research 20041101

• Levetiracetam as add-on therapy in generalised epilepsies.

  Seizure 20041001

• Pilot efficacy and tolerability: a randomized, placebo-controlled trial of levetiracetam for essential tremor.

  Movement disorders : official journal of the Movement Disorder Society 20041001

• Levetiracetam induces a rapid and sustained reduction of generalized spike-wave and clinical absence.

  Archives of neurology 20041001

• Anticonvulsant drugs in primary headaches prophylaxis.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20041001

• A validated chiral LC method for the enantioselective analysis of Levetiracetam and its enantiomer R-alpha-ethyl-2-oxo-pyrrolidine acetamide on amylose-based stationary phase.

  Journal of pharmaceutical and biomedical analysis 20040903

• Efficacy of levetiracetam in pharmacoresistant continuous spikes and waves during slow sleep.

  Acta neurologica Scandinavica 20040901

• Levetiracetam safety profiles and tolerability in epilepsy patients.

  Expert opinion on drug safety 20040901

• A pilot study of compassionate use of Levetiracetam in patients with generalised epilepsy.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20040901

• Psychopharmacology of anticonvulsants: levetiracetam as a synaptic vesicle protein modulator.

  The Journal of clinical psychiatry 20040901

• An open-label study of levetiracetam for the treatment of social anxiety disorder.

  The Journal of clinical psychiatry 20040901

• A prospective analysis of the outcome of levetiracetam in clinical practice.

  Neurology 20040810

• [Levetiracetam in combined therapy for focal epilepsy: experience with 80 patients].

  Der Nervenarzt 20040801

• Levetiracetam inhibits Na+-dependent Cl-/HCO3- exchange of adult hippocampal CA3 neurons from guinea-pigs.

  British journal of pharmacology 20040801

• Levetiracetam therapeutic monitoring in patients with epilepsy: effect of concomitant antiepileptic drugs.

  Therapeutic drug monitoring 20040801

• Levetiracetam potentiates the antidyskinetic action of amantadine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned primate model of Parkinson's disease.

  The Journal of pharmacology and experimental therapeutics 20040701

• Intracellular calcium increase in epileptiform activity: modulation by levetiracetam and lamotrigine.

  Epilepsia 20040701

• The activity of antiepileptic drugs as histone deacetylase inhibitors.

  Epilepsia 20040701

• Levetiracetam-induced thrombocytopenia.

  Epilepsia 20040701

• Levetiracetam in bipolar spectrum disorders: first evidence of efficacy in an open, add- on study.

  Human psychopharmacology 20040701

• The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam.

  Proceedings of the National Academy of Sciences of the United States of America 20040629

• Levetiracetam in the treatment of idiopathic hemifacial spasm.

  Neurology 20040608

• Antimyoclonic effect of levetiracetam in 13 patients with Unverricht-Lundborg disease: clinical observations.

  Epilepsia 20040601

• [Safety of levetiracetam as adjunctive therapy in epilepsy: the SKATE trial in Spain].

  Revista de neurologia 20040601

• New pharmacotherapies for pediatric seizures.

  Pediatric annals 20040601

• Efficacy and tolerability of the new antiepileptic drugs, I: Treatment of new-onset epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society.

  Epilepsia 20040501

• Efficacy and tolerability of the new antiepileptic drugs, II: Treatment of refractory epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society.

  Epilepsia 20040501

• Levetiracetam in focal epilepsy and hepatic porphyria: a case report.

  Epilepsia 20040501

• Efficacy and tolerability of the new antiepileptic drugs II: treatment of refractory epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society.

  Neurology 20040427

• Efficacy and tolerability of levetiracetam in children aged 10 years and younger: a clinical experience.

  Seizure 20040401

• Efficacy and tolerability of levetiracetam in patients with therapy-resistant epilepsy and learning disabilities.

  Seizure 20040401

• Levetiracetam in the treatment of Lennox-Gastaut syndrome.

  Pediatric neurology 20040401

• Levetiracetam prevents changes in levels of brain-derived neurotrophic factor and neuropeptide Y mRNA and of Y1- and Y5-like receptors in the hippocampus of rats undergoing amygdala kindling: implications for antiepileptogenic and mood-stabilizing properties.

  Epilepsy & behavior : E&B 20040401

• Levetiracetam in adult patients with and without learning disability: focus on behavioral adverse effects.

  Epilepsy & behavior : E&B 20040401

• Aromatase inhibition, testosterone, and seizures.

  Epilepsy & behavior : E&B 20040401

• 'Mu rhythm status' and clinical correlates.

  Clinical EEG and neuroscience 20040401

• Efficacy and safety of levetiracetam in pediatric migraine.

  Headache 20040301

• Enterocolitis: an adverse event in refractory epilepsy patients treated with levetiracetam?

  Seizure 20040301

• Levetiracetam during 1-year follow-up in children, adolescents, and young adults with refractory epilepsy.

  Epilepsy research 20040301

• Comparative pharmacokinetics and metabolism of levetiracetam, a new anti-epileptic agent, in mouse, rat, rabbit and dog.

  Xenobiotica; the fate of foreign compounds in biological systems 20040301

• Levetiracetam in progressive myoclonic epilepsy: an exploratory study in 9 patients.

  Neurology 20040224

• Levetiracetam improves choreic levodopa-induced dyskinesia in the MPTP-treated macaque.

  European journal of pharmacology 20040206

• The new antiepileptic drugs: scientific review.

  JAMA 20040204

• FDA notifications. UCB Pharma and FDA issue advisory letter.

  AIDS alert 20040201

• Inhibition of multidrug transporters by verapamil or probenecid does not alter blood-brain barrier penetration of levetiracetam in rats.

  Epilepsy research 20040201

• Anticonvulsant effects of levetiracetam and levetiracetam-diazepam combinations in experimental status epilepticus.

  Epilepsy research 20040201

• Discovery of 4-substituted pyrrolidone butanamides as new agents with significant antiepileptic activity.

  Journal of medicinal chemistry 20040129

• Levetiracetam improves paroxysmal symptoms in a patient with stiff-person syndrome.

  Neurology 20040127

• Levetiracetam protects against kainic acid-induced toxicity.

  Life sciences 20040123

• [Levetiracetam hepatitis].

  Medicina clinica 20040117

• Levetiracetam in the treatment of neuropathic pain: three case studies.

  The Clinical journal of pain 20040101

• Levetiracetam reduces spike-wave density and duration during continuous EEG monitoring in patients with idiopathic generalized epilepsy.

  Epilepsia 20040101

• The antiepileptic drug levetiracetam selectively modifies kindling-induced alterations in gene expression in the temporal lobe of rats.

  The European journal of neuroscience 20040101

• Psychiatric adverse events in patients with epilepsy and learning disabilities taking levetiracetam.

  Seizure 20040101

• Levetiracetam monotherapy for elderly patients with epilepsy.

  Seizure 20040101

• [Pharmacology in epilepsy. Where are we heading for?].

  Revista de neurologia 20040101

• High-performance liquid chromatographic determination of Levetiracetam in human plasma: comparison of different sample clean-up procedures.

  Biomedical chromatography : BMC 20040101

• Levetiracetam as migraine prophylaxis.

  The Clinical journal of pain 20040101

• Newer anticonvulsants in the treatment of bipolar disorder.

  The Journal of clinical psychiatry 20040101

• Antiepileptic drugs in migraine prophylaxis: state of the art.

  La Clinica terapeutica 20040101

• Clinical pharmacokinetics of levetiracetam.

  Clinical pharmacokinetics 20040101

• Levetiracetam Interferes With the L-dopa priming process in MPTP-lesioned drug-naive marmosets.

  Clinical neuropharmacology 20040101

• Seizure susceptibility of neuropeptide-Y null mutant mice in amygdala kindling and chemical-induced seizure models.

  Epilepsy research 20040101

• Spinal myoclonus with giant somatosensory evoked potentials and enhanced long-loop reflex: a case report.

  Functional neurology 20040101

• An open-label pilot study of levetiracetam for essential tremor.

  Clinical neuropharmacology 20040101

• Levetiracetam: relative bioavailability and bioequivalence of a 10% oral solution (750 mg) and 750-mg tablets.

  Journal of clinical pharmacology 20031201

• Levetiracetam: preliminary experience in patients with primary brain tumours.

  Seizure 20031201

• Levetiracetam in clinical use--a prospective observational study.

  Seizure 20031201

• Levetiracetam treatment of idiopathic generalised epilepsy.

  Seizure 20031201

• Unidirectional cross-tolerance from levetiracetam to carbamazepine in amygdala-kindled seizures.

  Epilepsia 20031201

• Levetiracetam and partial seizure subtypes: pooled data from three randomized, placebo-controlled trials.

  Epilepsia 20031201

• Serum concentrations of Levetiracetam in epileptic patients: the influence of dose and co-medication.

  Therapeutic drug monitoring 20031201

• [Effectiveness and tolerability of levetiracetam in 43 children and adolescents with epilepsy].

  Revista de neurologia 20031201

• Levetiracetam for phasic spasticity in multiple sclerosis.

  Archives of neurology 20031201

• Use of levetiracetam in a population of patients aged 65 years and older: a subset analysis of the KEEPER trial.

  Epilepsy & behavior : E&B 20031201

• Anxiolytic effects of the novel anti-epileptic drug levetiracetam in the elevated plus-maze test in the rat.

  European journal of pharmacology 20031114

• Discontinuation of levetiracetam because of behavioral side effects: a case-control study.

  Neurology 20031111

• Pharmacokinetics and metabolism of 14C-levetiracetam, a new antiepileptic agent, in healthy volunteers.

  European journal of clinical pharmacology 20031101

• Levetiracetam: treatment in epilepsy.

  Expert opinion on pharmacotherapy 20031101

• Effects of antiepileptic drugs on refractory seizures in the intact immature corticohippocampal formation in vitro.

  Epilepsia 20031101

• Novel antiepileptic drug levetiracetam decreases dyskinesia elicited by L-dopa and ropinirole in the MPTP-lesioned marmoset.

  Movement disorders : official journal of the Movement Disorder Society 20031101

• Future Pain Drugs - Europe 2003. 15-16 September 2003, London, UK.

  IDrugs : the investigational drugs journal 20031101

• Drug points: Weight loss associated with levetiracetam.

  BMJ (Clinical research ed.) 20031018

• Reduction of voltage-operated potassium currents by levetiracetam: a novel antiepileptic mechanism of action?

  Neuropharmacology 20031001

• Developmental outcome of levetiracetam, its major metabolite in humans, 2-pyrrolidinone N-butyric acid, and its enantiomer (R)-alpha-ethyl-oxo-pyrrolidine acetamide in a mouse model of teratogenicity.

  Epilepsia 20031001

• Seizure-free days observed in randomized placebo-controlled add-on trials with levetiracetam in partial epilepsy.

  Epilepsia 20031001

• Aggressive behavior of epilepsy patients in the course of levetiracetam add-on therapy: report of 33 mild to severe cases.

  Epilepsy & behavior : E&B 20031001

• Landau-Kleffner syndrome responsive to levetiracetam.

  Epilepsy & behavior : E&B 20031001

• Levetiracetam does not alter body weight: analysis of randomized, controlled clinical trials.

  Epilepsy research 20031001

• Tolerability of levetiracetam in elderly patients with CNS disorders.

  Epilepsy research 20031001

• Binding characteristics of [3H]ucb 30889 to levetiracetam binding sites in rat brain.

  European journal of pharmacology 20030930

• Localization and photoaffinity labelling of the levetiracetam binding site in rat brain and certain cell lines.

  European journal of pharmacology 20030930

• Pilot tolerability and effectiveness study of levetiracetam for postherpetic neuralgia.

  Neurology 20030923

• Psychiatric adverse events during levetiracetam therapy.

  Neurology 20030909

• Levetiracetam: a new therapeutic option for refractory epilepsy.

  International journal of clinical practice 20030901

• [Levetiracetam in children and adolescents with epilepsy].

  Revista de neurologia 20030901

• Oxcarbazepine, topiramate, zonisamide, and levetiracetam: potential use in neuropathic pain.

  The American journal of geriatric pharmacotherapy 20030901

• Levetiracetam as a treatment for tardive dyskinesia: a case report.

  Neurology 20030812

• Levetiracetam monotherapy during pregnancy: a case series.

  Epilepsy & behavior : E&B 20030801

• Antihyperalgesic effect of levetiracetam in neuropathic pain models in rats.

  European journal of pharmacology 20030718

• Analysis of the antiepileptic drug keppra by capillary electrophoresis.

  Journal of chromatography. A 20030704

• Desynchronizing effect of levetiracetam on epileptiform responses in rat hippocampal slices.

  Neuroreport 20030701

• Levetiracetam in the treatment of acute mania: an open add-on study with an on-off-on design.

  The Journal of clinical psychiatry 20030701

• Expression of brain-derived neurotrophic factor (BDNF) and inducible nitric oxide synthase (iNOS) in rat astrocyte cultures treated with Levetiracetam.

  Brain research 20030627

• Levetiracetam monotherapy for liver transplant patients with seizures.

  Transplantation proceedings 20030601

• Levetiracetam in the treatment of rapid cycling bipolar disorder.

  Journal of psychopharmacology (Oxford, England) 20030601

• Acute psychosis associated with levetiracetam.

  Epileptic disorders : international epilepsy journal with videotape 20030601

• [Levetiracetam in the treatment of epilepsy].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20030529

• Anxiolytic profile of the antiepileptic drug levetiracetam in the Vogel conflict test in the rat.

  European journal of pharmacology 20030523

• The KEEPER trial: levetiracetam adjunctive treatment of partial-onset seizures in an open-label community-based study.

  Epilepsy research 20030501

• Meeting the challenge of treating epilepsy.

  Epileptic disorders : international epilepsy journal with videotape 20030501

• Antiepileptogenesis, neuroprotection, and disease modification in the treatment of epilepsy: focus on levetiracetam.

  Epileptic disorders : international epilepsy journal with videotape 20030501

• The ideal pharmacokinetic properties of an antiepileptic drug: how close does levetiracetam come?

  Epileptic disorders : international epilepsy journal with videotape 20030501

• Efficacy of levetiracetam in partial seizures.

  Epileptic disorders : international epilepsy journal with videotape 20030501

• Long-term experience with levetiracetam.

  Epileptic disorders : international epilepsy journal with videotape 20030501

• Levetiracetam: preliminary efficacy in generalized seizures.

  Epileptic disorders : international epilepsy journal with videotape 20030501

• Preliminary efficacy of levetiracetam in children.

  Epileptic disorders : international epilepsy journal with videotape 20030501

• Preliminary efficacy of levetiracetam in monotherapy.

  Epileptic disorders : international epilepsy journal with videotape 20030501

• Safety profile of levetiracetam.

  Epileptic disorders : international epilepsy journal with videotape 20030501

• Role of levetiracetam in the treatment of epilepsy.

  Epileptic disorders : international epilepsy journal with videotape 20030501

• Efficacy of levetiracetam in a patient with Unverricht-Lundborg progressive myoclonic epilepsy.

  Neurology 20030422

• Levetiracetam has no significant gamma-aminobutyric acid-related effect on paired-pulse interaction in the dentate gyrus of rats.

  European journal of pharmacology 20030418

• Efficacy and tolerability of levetiracetam during 1-year follow-up in patients with refractory epilepsy.

  Seizure 20030401

• Clinical experience of marketed Levetiracetam in an epilepsy clinic-a one year follow up study.

  Seizure 20030401

• An open-label study of levetiracetam at individualised doses between 1000 and 3000 mg day(-1) in adult patients with refractory epilepsy.

  Seizure 20030401

• Levetiracetam monotherapy for primary generalised epilepsy.

  Seizure 20030401

• Levetiracetam monotherapy for newly diagnosed epilepsy patients.

  Seizure 20030401

• Levetiracetam for benign epilepsy of childhood with centrotemporal spikes-three cases.

  Seizure 20030401

• Dramatic effect of levetiracetam on epileptic negative myoclonus.

  Acta neurologica Scandinavica 20030401

• Maintenance of improvement in health-related quality of life during long-term treatment with levetiracetam.

  Epilepsy & behavior : E&B 20030401

• A systematic review of the behavioral effects of levetiracetam in adults with epilepsy, cognitive disorders, or an anxiety disorder during clinical trials.

  Epilepsy & behavior : E&B 20030401

• Levetiracetam reduces caffeine-induced Ca2+ transients and epileptiform potentials in hippocampal neurons.

  Neuroreport 20030303

• Electrophysiological, neurochemical and regional effects of levetiracetam in the rat pilocarpine model of temporal lobe epilepsy.

  Seizure 20030301

• Microemulsion electrokinetic chromatography applied for separation of levetiracetam from other antiepileptic drugs in polypharmacy.

  Electrophoresis 20030301

• The pharmacokinetic characteristics of levetiracetam.

  Methods and findings in experimental and clinical pharmacology 20030301

• Correlation of levetiracetam concentrations between serum and saliva.

  Therapeutic drug monitoring 20030201

• Levetiracetam, a new antiepileptic agent: lack of in vitro and in vivo pharmacokinetic interaction with valproic acid.

  Epilepsia 20030201

• Levetiracetam efficacy in refractory partial-onset seizures, especially after failed epilepsy surgery.

  Epilepsia 20030201

• Effects of antiepileptic comedication on levetiracetam pharmacokinetics: a pooled analysis of data from randomized adjunctive therapy trials.

  Epilepsy research 20030201

• Evidence for sustained efficacy of levetiracetam as add-on epilepsy therapy.

  Epilepsy research 20030201

• Effects of lamotrigine and levetiracetam on seizure development in a rat amygdala kindling model.

  Epilepsy research 20030201

• Clinically relevant reduction of lamotrigine concentrations by carbamazepine.

  European psychiatry : the journal of the Association of European Psychiatrists 20030201

• Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.

  Neuroscience letters 20030102

• A paradoxical effect of levetiracetam may be seen in both children and adults with refractory epilepsy.

  Seizure 20030101

• Successful treatment of pharmacoresistent continuous spike wave activity during slow sleep with levetiracetam.

  European journal of pediatrics 20030101

• Levetiracetam control of myoclonus in a patient with Creutzfeldt-Jakob disease.

  European neurology 20030101

• Effect of levetiracetam in refractory childhood epilepsy syndromes.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20030101

• The SKATE study: interim analysis.

  International journal of clinical practice 20030101

• Effect of levetiracetam on epileptiform discharges in human neocortical slices.

  Epilepsia 20021201

• Levetiracetam may be more effective for late-onset partial epilepsy.

  Archives of neurology 20021201

• Effect of levetiracetam on rapid motor learning in humans.

  Archives of neurology 20021201

• Antiepileptic drug therapy for adults: when to initiate and how to choose.

  Mayo Clinic proceedings 20021201

• New antiepileptic drug therapies.

  Neurologic clinics 20021101

• Improvement of a patient with stuttering on levetiracetam.

  Neurology 20021022

• Amelioration of spinal myoclonus with levetiracetam.

  Journal of neurology, neurosurgery, and psychiatry 20021001

• The effects of levetiracetam on objective and subjective sleep parameters in healthy volunteers and patients with partial epilepsy.

  Journal of sleep research 20020901

• [Characteristics and indications of levetiracetam].

  Revista de neurologia 20020901

• Levetiracetam in autistic children: an open-label study.

  Journal of developmental and behavioral pediatrics : JDBP 20020801

• [Effectiveness and tolerability of the new antiepileptic drugs: the position of levetiracetam].

  Revista de neurologia 20020801

• Aggravation of partial seizures by antiepileptic drugs: is there evidence from clinical trials?

  Neurology 20020709

• The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currents.

  British journal of pharmacology 20020701

• Levetiracetam does not alter the pharmacokinetics of an oral contraceptive in healthy women.

  Epilepsia 20020701

• [Levetiracetam: an anti-epileptic drug with interesting pharmacokinetic properties].

  Nederlands tijdschrift voor geneeskunde 20020629

• Levetiracetam in refractory pediatric epilepsy.

  Journal of child neurology 20020601

• [Levetiracetam: a molecule with a novel mechanism of action in the pharmaceutical treatment of epilepsy].

  Ideggyogyaszati szemle 20020520

• Efficacy and safety of levetiracetam in children with partial seizures: an open-label trial.

  Epilepsia 20020501

• Levetiracetam in the treatment of paroxysmal kinesiogenic choreoathetosis.

  Movement disorders : official journal of the Movement Disorder Society 20020501

• Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

  The Journal of biological chemistry 20020419

• A new antiepileptic drug.

  Journal of neurology, neurosurgery, and psychiatry 20020401

• Effects of the novel antiepileptic drug levetiracetam on spontaneous recurrent seizures in the rat pilocarpine model of temporal lobe epilepsy.

  Epilepsia 20020401

• Levetiracetam--a new drug for epilepsy.

  Drug and therapeutics bulletin 20020401

• The 'number needed to treat' with levetiracetam (LEV): comparison with the other new antiepileptic drugs (AEDs).

  Seizure 20020401

• The new antiepileptic drug levetiracetam normalises chlordiazepoxide withdrawal-induced anxiety in mice.

  European journal of pharmacology 20020329

• Levetiracetam opposes the action of GABAA antagonists in hypothalamic neurones.

  Neuropharmacology 20020301

• A comparison of the efficacy of carbamazepine and the novel anti-epileptic drug levetiracetam in the tetanus toxin model of focal complex partial epilepsy.

  British journal of pharmacology 20020301

• Suppression of cortical myoclonus by levetiracetam.

  Movement disorders : official journal of the Movement Disorder Society 20020301

• Levetiracetam: a different approach to the pharmacotherapy of epilepsy.

  The Annals of pharmacotherapy 20020201

• Carbamazepine toxicity during combination therapy with levetiracetam: a pharmacodynamic interaction.

  Epilepsy research 20020201

• Levetiracetam for acute mania.

  The American journal of psychiatry 20020101

• Newer therapies in the drug treatment of epilepsy.

  The Annals of pharmacotherapy 20020101

• Dose-response effect of levetiracetam 1000 and 2000 mg/day in partial epilepsy.

  Epilepsy research 20020101

• Selective blockade of N-type calcium channels by levetiracetam.

  Epilepsia 20020101

• Three new drugs for epilepsy: levetiracetam, oxcarbazepine, and zonisamide.

  Journal of child neurology 20020101

• Using the new antiepilepsy drugs in children.

  Journal of child neurology 20020101

• The clinical challenge of posthypoxic myoclonus.

  Advances in neurology 20020101

• A case of levetiracetam (Keppra) poisoning with clinical and toxicokinetic data.

  Journal of toxicology. Clinical toxicology 20020101

• Pharmacological characterization of the 6 Hz psychomotor seizure model of partial epilepsy.

  Epilepsy research 20011201

• Effect of levetiracetam in patients with epilepsy and interictal epileptiform discharges.

  Seizure 20011201

• Pharmacokinetic study of levetiracetam in children.

  Epilepsia 20011201

• Levetiracetam psychosis in children with epilepsy.

  Epilepsia 20011201

• Lack of effect of repeated administration of levetiracetam on the pharmacodynamic and pharmacokinetic profiles of warfarin.

  Epilepsy research 20011101

• A systematic review of the safety profile of levetiracetam: a new antiepileptic drug.

  Epilepsy research 20011101

• Levetiracetam: a novel antiepileptic drug.

  Pharmacotherapy 20011101

• [Levetiracetam].

  Neurologia (Barcelona, Spain) 20011101

• A pilot tolerability and efficacy study of levetiracetam in patients with chronic myoclonus.

  Neurology 20010925

• Suppression of post-hypoxic and post-encephalitic myoclonus with levetiracetam.

  Neurology 20010925

• Effect of levetiracetam on human corticospinal excitability.

  Neurology 20010911

• Levetiracetam, oxcarbazepine, remacemide and zonisamide for drug resistant localization-related epilepsy: a systematic review.

  Epilepsy research 20010901

• Repeated administration of the novel antiepileptic agent levetiracetam does not alter digoxin pharmacokinetics and pharmacodynamics in healthy volunteers.

  Epilepsy research 20010801

• Levetiracetam.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20010701

• A microdialysis study of the novel antiepileptic drug levetiracetam: extracellular pharmacokinetics and effect on taurine in rat brain.

  British journal of pharmacology 20010701

• Pharmacokinetics of levetiracetam and its enantiomer (R)-alpha-ethyl-2-oxo-pyrrolidine acetamide in dogs.

  Epilepsia 20010701

• Long-term continuation of levetiracetam in patients with refractory epilepsy.

  Neurology 20010626

• Levetiracetam inhibits the high-voltage-activated Ca(2+) current in pyramidal neurones of rat hippocampal slices.

  Neuroscience letters 20010622

• Levetiracetam does not modulate neuronal voltage-gated Na+ and T-type Ca2+ currents.

  Seizure 20010601

• Neuroprotective properties of the novel antiepileptic drug levetiracetam in the rat middle cerebral artery occlusion model of focal cerebral ischemia.

  Seizure 20010601

• The 'number needed to treat' with Levetiracetam (LEV): comparison with the other new antiepileptic drugs (AEDs).

  Seizure 20010401

• Suppression of post-hypoxic and post-encephalitic myoclonus with levetiracetam.

  Neurology 20010213

• Levetiracetam add-on for drug-resistant localization related (partial) epilepsy.

  The Cochrane database of systematic reviews 20010101

• Effects of antiepileptic drugs on cognition.

  Epilepsia 20010101

• Issues in the treatment of epilepsy.

  Epilepsia 20010101

• Levetiracetam: the preclinical profile of a new class of antiepileptic drugs?

  Epilepsia 20010101

• Pharmacokinetic considerations in prescribing antiepileptic drugs.

  Epilepsia 20010101

• Pharmacokinetics of levetiracetam.

  Epilepsia 20010101

• Concerns with antiepileptic drug initiation: safety, tolerability, and efficacy.

  Epilepsia 20010101

• Efficacy of levetiracetam: a review of three pivotal clinical trials.

  Epilepsia 20010101

• Safety profile of levetiracetam.

  Epilepsia 20010101

• Use of levetiracetam in special populations.

  Epilepsia 20010101

• The place of levetiracetam in the treatment of epilepsy.

  Epilepsia 20010101

• Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy.

  European journal of pharmacology 19980724

• The novel antiepileptic drug levetiracetam (ucb L059) appears to act via a specific binding site in CNS membranes.

  European journal of pharmacology 19951114

• Effects of nootropic drugs in a scopolamine-induced amnesia model in mice.

  Psychopharmacology 19880101