1029716-94-6 | 3,5-Difluoro-4-carboxyphenylboronic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	96%	in stock	$32.00	$22.00
1g	96%	in stock	$88.00	$61.00
5g	96%	in stock	$342.00	$239.00
10g	96%	in stock	$603.00	$422.00
25g	96%	in stock	$1,193.00	$835.00

Description

• Catalog Number: AD70883
• Chemical Name: 3,5-Difluoro-4-carboxyphenylboronic acid
• CAS Number: 1029716-94-6
• Molecular Formula: C7H5BF2O4
• Molecular Weight: 201.92
• MDL Number: MFCD13181636
• SMILES: OB(c1cc(F)c(c(c1)F)C(=O)O)O

Computed Properties

• Complexity: 214
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 2

Upstream Synthesis Route

3,5-Difluoro-4-carboxyphenylboronic acid is a versatile chemical compound that is widely used in chemical synthesis. It serves as a key building block in the creation of various pharmaceuticals, agrochemicals, and materials due to its unique properties and reactivity.One of the main applications of 3,5-Difluoro-4-carboxyphenylboronic acid is in Suzuki-Miyaura cross-coupling reactions. This compound acts as a valuable boronic acid derivative that can undergo coupling reactions with aryl halides or pseudohalides in the presence of a palladium catalyst. This type of reaction allows for the formation of complex organic molecules with high efficiency and selectivity.Additionally, 3,5-Difluoro-4-carboxyphenylboronic acid can also be utilized as a ligand in transition metal-catalyzed transformations. Its boronic acid functionality can coordinate with transition metal species, enabling it to participate in various catalytic processes such as C-H activation, asymmetric synthesis, and cross-coupling reactions.Moreover, this compound has found applications in the synthesis of fluorinated aromatic compounds, which are of great interest in medicinal chemistry and materials science. The difluoro and carboxy groups present in 3,5-Difluoro-4-carboxyphenylboronic acid offer opportunities for further functionalization and diversification of chemical structures, leading to the discovery of new bioactive compounds and advanced materials.