103-84-4 | Acetanilide

Packsize	Purity	Availability	Price	Discounted Price
1g	99%	in stock	$13.00	$9.00
5g	99%	in stock	$15.00	$10.00
25g	99%	in stock	$19.00	$13.00
100g	>99.5%(GC)	in stock	$28.00	$20.00
250g	>99.5%(GC)	in stock	$44.00	$31.00
1kg	≥ 99% (Assay)	in stock	$148.00	$104.00
5kg	≥ 99% (Assay)	in stock	$483.00	$338.00
10kg	≥ 99% (Assay)	in stock	$876.00	$613.00
25kg	≥ 99% (Assay)	in stock	$2,037.00	$1,426.00

Description

• Catalog Number: AB45506
• Chemical Name: Acetanilide
• CAS Number: 103-84-4
• Molecular Formula: C8H9NO
• Molecular Weight: 135.1632
• MDL Number: MFCD00008674
• SMILES: CC(=O)Nc1ccccc1

Computed Properties

• Complexity: 116
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 1.2

Literature

• One-pot/sequential native chemical ligation using N-sulfanylethylanilide peptide.

  Chemical record (New York, N.Y.) 20121001

• Trigonal Mn3 and Co3 clusters supported by weak-field ligands: a structural, spectroscopic, magnetic, and computational investigation into the correlation of molecular and electronic structure.

  Inorganic chemistry 20121001

• catena-Poly[(μ-anilido)(μ-1,2-dimeth-oxy-ethane-κ(3)-O,O':O)sodium].

  Acta crystallographica. Section E, Structure reports online 20121001

• Terminal phosphinidene formation via tantalaziridine complexes.

  Dalton transactions (Cambridge, England : 2003) 20120828

• [Triclocarban antibacterial activity on resistant staphylococci, streptococci, and enterococci].

  Medecine et maladies infectieuses 20120601

• Short-term and low-dose prednisolone administration reduces aromatase inhibitor-induced arthralgia in patients with breast cancer.

  Anticancer research 20120601

• Cloning and characterization of a novel amidase from Paracoccus sp. M-1, showing aryl acylamidase and acyl transferase activities.

  Applied microbiology and biotechnology 20120501

• Intramolecular 1,3-dipolar cycloaddition reactions in the synthesis of complex annelated quinolines, α-carbolines and coumarins.

  Molecular diversity 20120501

• Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors. 1. Exploration of [5,6]-fused bicyclic scaffolds.

  Journal of medicinal chemistry 20120412

• Proton transfer from H₂O to p-substituted anilide anion: can the size of water cluster influence the N⁻···H-OH→N-H···OH⁻ switching.

  Journal of molecular modeling 20120401

• Electrochemically synthesized polymers in molecular imprinting for chemical sensing.

  Analytical and bioanalytical chemistry 20120401

• Malaria-infected mice are completely cured by one 6 mg/kg oral dose of a new monomeric trioxane sulfide combined with mefloquine.

  Journal of medicinal chemistry 20120112

• Isolation and characterization of the thrombin-like enzyme from Cryptelytrops albolabris (white-lipped tree viper) venom.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20120101

• Bis[μ-N-(diethyl-amino-κN)dimethyl-silylanilido-κN:N]bis-[chlorido-cobalt(II)].

  Acta crystallographica. Section E, Structure reports online 20120101

• The immunomodulation of acetylcholinesterase in zhikong scallop Chlamys farreri.

  PloS one 20120101

• Pharmacokinetic Study of Di-Phenyl-Di-(2,4-Difluobenzohydroxamato)Tin(IV): Novel Metal-Based Complex with Promising Antitumor Potential.

  Bioinorganic chemistry and applications 20120101

• Long-term species, sexual and individual variations in foraging strategies of fur seals revealed by stable isotopes in whiskers.

  PloS one 20120101

• [Appropriate pharmacotherapy in patients with chronic kidney disease - new approach - ].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101

• Modulation of La Crosse Virus Infection in Aedes albopictus Mosquitoes Following Larval Exposure to Coffee Extracts.

  Frontiers in physiology 20120101

• Use of the University of Minnesota Biocatalysis/Biodegradation Database for study of microbial degradation.

  Microbial informatics and experimentation 20120101

• Ru (III) catalyzed oxidation of aliphatic ketones by N-bromosuccinimide in aqueous acetic acid: a kinetic study.

  TheScientificWorldJournal 20120101

• Stable isotope tracking of endangered sea turtles: validation with satellite telemetry and δ15N analysis of amino acids.

  PloS one 20120101

• Pre-partum diet of adult female bearded seals in years of contrasting ice conditions.

  PloS one 20120101

• Eleven-year trend in acetanilide pesticide degradates in the Iowa River, Iowa.

  Journal of environmental quality 20120101

• White phosphorus activation at a metal-phosphorus triple bond: a new route to cyclo-triphosphorus or cyclo-pentaphosphorus complexes of niobium.

  Inorganic chemistry 20111219

• Bis(μ(2)-η:η-2,4,6-trimethyl-benzonitrile)-bis-[(N-isopropyl-3,5-dimethyl-anilido)molybdenum(III)](Mo-Mo).

  Acta crystallographica. Section E, Structure reports online 20111201

• Preparation of human drug metabolites using fungal peroxygenases.

  Biochemical pharmacology 20111001

• Monoamine oxidase inhibition by selected anilide derivatives.

  European journal of medicinal chemistry 20111001

• A terminal nickel(II) anilide complex featuring an unsymmetrically substituted amido pincer ligand: synthesis and reactivity.

  Dalton transactions (Cambridge, England : 2003) 20110921

• Expedient synthesis of N-acyl anthranilamides and β-enamine amides by the Rh(III)-catalyzed amidation of aryl and vinyl C-H bonds with isocyanates.

  Journal of the American Chemical Society 20110803

• Effects of transforaminal injection for degenerative lumbar scoliosis combined with spinal stenosis.

  Annals of rehabilitation medicine 20110801

• N,N'-Dialkylaminoalkylcarbonyl (DAAC) prodrugs and aminoalkylcarbonyl (AAC) prodrugs of 4-hydroxyacetanilide and naltrexone with improved skin permeation properties.

  Bioorganic & medicinal chemistry letters 20110701

• Determination of acetanilide herbicides in cereal crops using accelerated solvent extraction, solid-phase extraction and gas chromatography-electron capture detector.

  Journal of separation science 20110701

• Early drug discovery and the rise of pharmaceutical chemistry.

  Drug testing and analysis 20110601

• Mechanistic understanding of the unexpected meta selectivity in copper-catalyzed anilide C-H bond arylation.

  Journal of the American Chemical Society 20110525

• Effectiveness and pathways of electrochemical degradation of pretilachlor herbicides.

  Journal of hazardous materials 20110515

• Half-zirconocene anilide complexes: synthesis, characterization and catalytic properties for ethylene polymerization and copolymerization with 1-hexene.

  Dalton transactions (Cambridge, England : 2003) 20110507

• Effects of dynamical couplings in IR spectra of the hydrogen bond in N-phenylacrylamide crystals.

  The journal of physical chemistry. A 20110505

• ATP and its N⁶-substituted analogues: parameterization, molecular dynamics simulation and conformational analysis.

  Journal of molecular modeling 20110501

• Novel pyrrolidine melanin-concentrating hormone receptor 1 antagonists with reduced hERG inhibition.

  Bioorganic & medicinal chemistry letters 20110415

• Analysis of δ15N values in mollusk shell organic matrix by elemental analysis/isotope ratio mass spectrometry without acidification: an evaluation and effects of long-term preservation.

  Rapid communications in mass spectrometry : RCM 20110315

• Hydractinia echinata test system. II. SAR toxicity study of some anilide derivatives of Naphthol-AS type.

  Chemosphere 20110301

• Photoionization-induced water migration in the amide group of trans-acetanilide-(H2O)1 in the gas phase.

  The journal of physical chemistry. A 20110210

• Chlorido{N-[(diethyl-amino)-dimethyl-sil-yl]anilido-κN}(N,N,N',N'-tetra-methyl-ethane-1,2-diamine-κN,N')cobalt(II).

  Acta crystallographica. Section E, Structure reports online 20110201

• [Study on the chemical constituents of endophytic fungus Fimetariella rabenhorstii isolated from Aquilaria sinensis].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110201

• Biodegradation and mineralization of metolachlor and alachlor by Candida xestobii.

  Journal of agricultural and food chemistry 20110126

• Carbon monoxide stimulates global protein methylation via its inhibitory action on cystathionine β-synthase.

  Journal of clinical biochemistry and nutrition 20110101

• Isotopic investigation of contemporary and historic changes in penguin trophic niches and carrying capacity of the southern Indian ocean.

  PloS one 20110101

• Bioprotective properties of Dragon's blood resin: in vitro evaluation of antioxidant activity and antimicrobial activity.

  BMC complementary and alternative medicine 20110101

• Acetaminophen-cysteine adducts during therapeutic dosing and following overdose.

  BMC gastroenterology 20110101

• Asthma in sickle cell disease: implications for treatment.

  Anemia 20110101

• Dimethyl (E)-2-(N-phenyl-acetamido)-but-2-enedioate.

  Acta crystallographica. Section E, Structure reports online 20110101

• RMDAP: a versatile, ready-to-use toolbox for multigene genetic transformation.

  PloS one 20110101

• Recent trends in pulmonary arterial hypertension.

  Lung India : official organ of Indian Chest Society 20110101

• Age-related changes in the hepatic pharmacology and toxicology of paracetamol.

  Current gerontology and geriatrics research 20110101

• Sequential isotopic signature along gladius highlights contrasted individual foraging strategies of jumbo squid (Dosidicus gigas).

  PloS one 20110101

• Ecosystem resilience and threshold response in the Galápagos coastal zone.

  PloS one 20110101

• Iron limitation of a springtime bacterial and phytoplankton community in the ross sea: implications for vitamin b(12) nutrition.

  Frontiers in microbiology 20110101

• Discovery of a potent and orally available acyl-CoA: cholesterol acyltransferase inhibitor as an anti-atherosclerotic agent: (4-phenylcoumarin)acetanilide derivatives.

  Chemical & pharmaceutical bulletin 20110101

• Discovery of a novel acyl-CoA: cholesterol acyltransferase inhibitor: the synthesis, biological evaluation, and reduced adrenal toxicity of (4-phenylcoumarin)acetanilide derivatives with a carboxylic acid moiety.

  Chemical & pharmaceutical bulletin 20110101

• New short term prediction method for chemical carcinogenicity by hepatic transcript profiling following 28-day toxicity tests in rats.

  Cancer informatics 20110101

• Strategies used to inhibit postoperative swelling following removal of impacted lower third molar.

  Dental research journal 20110101

• Beyond readability: investigating coherence of clinical text for consumers.

  Journal of medical Internet research 20110101

• Environmental forcing of nitrogen fixation in the eastern tropical and sub-tropical North Atlantic Ocean.

  PloS one 20110101

• Disruption of a Novel NADH-Glutamate Synthase2 Gene Caused Marked Reduction in Spikelet Number of Rice.

  Frontiers in plant science 20110101

• What do we (not) know about how paracetamol (acetaminophen) works?

  Journal of clinical pharmacy and therapeutics 20101201

• Evaluating human liver reserve function by measuring serum concentrations of phenacetin and its metabolites.

  Journal of digestive diseases 20101201

• Solvent-free aromatic C-H functionalisation/halogenation reactions.

  Dalton transactions (Cambridge, England : 2003) 20101121

• Anilide activation of adjacent C-H bonds in the palladium-catalysed Fujiwara-Moritani reaction.

  Dalton transactions (Cambridge, England : 2003) 20101121

• Subtype-selective Na(v)1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives.

  Bioorganic & medicinal chemistry letters 20101115

• Community structure, trophic position and reproductive mode of soil and bark-living oribatid mites in an alpine grassland ecosystem.

  Experimental & applied acarology 20101101

• N-(3-Cyanophenyl)-2-phenylacetamide, an effective inhibitor of morbillivirus-induced membrane fusion with low cytotoxicity.

  The Journal of general virology 20101101

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• A mimic of the pyruvate dehydrogenase complex.

  Bioorganic & medicinal chemistry letters 20101015

• Synthesis and activity of N-sulfonylamides of tripeptides as potential urokinase inhibitors.

  Protein and peptide letters 20101001

• Survey and qualification of internal standards for quantification by 1H NMR spectroscopy.

  Journal of pharmaceutical and biomedical analysis 20100905

• First C-H activation route to oxindoles using copper catalysis.

  Organic letters 20100806

• Changes in herbivore control in arable fields by detrital subsidies depend on predator species and vary in space.

  Oecologia 20100801

• Diverging climate trends in Mongolian taiga forests influence growth and regeneration of Larix sibirica.

  Oecologia 20100801

• Chloridobis{N-[(dimethyl-amino)-dimethyl-sil-yl]-2,6-dimethyl-anilido-κN,N'}titanium(III).

  Acta crystallographica. Section E, Structure reports online 20100801

• Rh catalyzed olefination and vinylation of unactivated acetanilides.

  Journal of the American Chemical Society 20100728

• A medicinal chemist's guide to molecular interactions.

  Journal of medicinal chemistry 20100722

• Rhenium-catalyzed synthesis of indenones by novel dehydrative trimerization of aryl aldehydes via C-H bond activation.

  Organic letters 20100702

• Modelling active sites for the Beckmann rearrangement reaction in boron-containing zeolites and their interaction with probe molecules.

  Physical chemistry chemical physics : PCCP 20100628

• Gene transcription in Daphnia magna: effects of acute exposure to a carbamate insecticide and an acetanilide herbicide.

  Aquatic toxicology (Amsterdam, Netherlands) 20100505

• Molecular characterization of a novel bacterial aryl acylamidase belonging to the amidase signature enzyme family.

  Molecules and cells 20100501

• Hydrogen/deuterium exchange on aromatic rings during atmospheric pressure chemical ionization mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20100415

• Spectroscopic investigations of the chiral interactions of metolachlor and its (S)-isomer with lipase and phosphatase.

  Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20100401

• 6,8-Di-C-glycosyl flavonoids from Dendrobium huoshanense.

  Journal of natural products 20100226

• Investigations of interhydrogen bond dynamical coupling effects in the polarized IR spectra of acetanilide crystals.

  The journal of physical chemistry. A 20100204

• Comparison of methods for proanthocyanidin extraction from pine (Pinus densiflora) needles and biological activities of the extracts.

  Nutrition research and practice 20100201

• MRP isoforms and BCRP mediate sulfate conjugate efflux out of BeWo cells.

  International journal of pharmaceutics 20100115

• The effect of transcatheter arterial chemoembolization on phase II drug metabolism enzymes in patients with hepatocellular carcinoma.

  Cancer chemotherapy and pharmacology 20100101

• Isolation and characterization of the thrombin-like enzyme from Cryptelytrops purpureomaculatus venom.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20100101

• Derived Reference Doses (RfDs) for the environmental degradates of the herbicides alachlor and acetochlor: results of an independent expert panel deliberation.

  Regulatory toxicology and pharmacology : RTP 20100101

• Leucine aminopeptidase, beta-glucosidase and alkaline phosphatase activity rates and their significance in nutrient cycles in some coastal Mediterranean sites.

  Marine drugs 20100101

• Non-invasive index of liver fibrosis induced by alcohol, thioacetamide and Schistosomal infection in mice.

  BMC gastroenterology 20100101

• The TLR4/TRIF-Mediated Activation of NLRP3 Inflammasome Underlies Endotoxin-Induced Liver Injury in Mice.

  Gastroenterology research and practice 20100101

• TRPV1 in brain is involved in acetaminophen-induced antinociception.

  PloS one 20100101

• Recent advances in management of bladder overactivity.

  F1000 medicine reports 20100101

• Cellular locations of proteinases and association with vesicles in Porphyromonas gingivalis.

  European journal of medical research 20100101

• RACK1 associates with muscarinic receptors and regulates M(2) receptor trafficking.

  PloS one 20100101

• Pravastatin provides antioxidant activity and protection of erythrocytes loaded Primaquine.

  International journal of medical sciences 20100101

• 3D hepatic cultures simultaneously maintain primary hepatocyte and liver sinusoidal endothelial cell phenotypes.

  PloS one 20100101

• Synthesis and anticonvulsant activity of some alkanamide derivatives.

  Arzneimittel-Forschung 20100101

• Comparison of the phenolic content and antioxidant activities of Apocynum venetum L. (Luo-Bu-Ma) and two of its alternative species.

  International journal of molecular sciences 20100101

• 'Protective premedication': a comparative study of acetaminophen, gabapentin and combination of acetaminophen with gabapentin for post-operative analgesia.

  Journal of anaesthesiology, clinical pharmacology 20100101

• [Analysis of multiple cephalosporins in blood and urine by HPLC].

  Fa yi xue za zhi 20091201

• Synthesis of some novel pyrazolo[3,4-b]pyridine and pyrazolo[3,4-d]pyrimidine derivatives bearing 5,6-diphenyl-1,2,4-triazine moiety as potential antimicrobial agents.

  European journal of medicinal chemistry 20091101

• Nicotine, acetanilide and urea multi-level 2H-, 13C- and 15N-abundance reference materials for continuous-flow isotope ratio mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20091101

• Dehydro-abietic acid.

  Acta crystallographica. Section E, Structure reports online 20091001

• 2-[(2,6-Diethyl-phen-yl)imino-meth-yl]-N-(2-methoxy-phen-yl)aniline.

  Acta crystallographica. Section E, Structure reports online 20091001

• Synthesis and pharmacological evaluation of N-phenyl-acetamide sulfonamides designed as novel non-hepatotoxic analgesic candidates.

  European journal of medicinal chemistry 20090901

• Adsorption, desorption and dissipation of metolachlor in surface and subsurface soils.

  Pest management science 20090901

• Sex-dependent disposition of acetaminophen sulfate and glucuronide in the in situ perfused mouse liver.

  Drug metabolism and disposition: the biological fate of chemicals 20090901

• Isomer selective infrared spectroscopy of supersonically cooled cis- and trans-N-phenylamides in the region from the amide band to NH stretching vibration.

  Physical chemistry chemical physics : PCCP 20090807

• Methemoglobinemia and sulfhemoglobinemia in two pediatric patients after ingestion of hydroxylamine sulfate.

  The western journal of emergency medicine 20090801

• Study of the Beckmann rearrangement of acetophenone oxime over porous solids by means of solid state NMR spectroscopy.

  Physical chemistry chemical physics : PCCP 20090707

• Discovery of novel acetanilide derivatives as potent and selective beta3-adrenergic receptor agonists.

  European journal of medicinal chemistry 20090601

• CYP1A1 and CYP1A2 expression: comparing 'humanized' mouse lines and wild-type mice; comparing human and mouse hepatoma-derived cell lines.

  Toxicology and applied pharmacology 20090515

• Decomposers and root feeders interactively affect plant defence in Sinapis alba.

  Oecologia 20090501

• Determination and pharmacokinetics of a new diorganotin(IV) complex dibutyldi(4-chlorobenzohydroxamato)tin(IV) in rat plasma by a high performance liquid chromatographic method.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090501

• A meta-selective copper-catalyzed C-H bond arylation.

  Science (New York, N.Y.) 20090320

• Formulation and characterization of a compacted multiparticulate system for modified release of water-soluble drugs--part 1--acetaminophen.

  Drug development and industrial pharmacy 20090301

• 3-(2-Acetamido-phen-yl)sydnone.

  Acta crystallographica. Section E, Structure reports online 20090301

• Structure-based drug design of novel Aurora kinase A inhibitors: structural basis for potency and specificity.

  Journal of medicinal chemistry 20090226

• N-->S acyl-transfer-mediated synthesis of peptide thioesters using anilide derivatives.

  Organic letters 20090219

• Anti-inflammatory activity and PGE2 inhibitory properties of novel phenylcarbamoylmethyl ester-containing compounds.

  Molecules (Basel, Switzerland) 20090211

• Femtosecond IR pump-probe spectroscopy of nonlinear energy localization in protein models and model proteins.

  Journal of biological physics 20090201

• The Davydov/Scott model for energy storage and transport in proteins.

  Journal of biological physics 20090201

• Tilting after Dutch windmills: probably no long-lived Davydov solitons in proteins.

  Journal of biological physics 20090201

• Transcriptomic comparison of Aspergillus niger growing on two different sugars reveals coordinated regulation of the secretory pathway.

  BMC genomics 20090101

• Highly selective stereodivergent synthesis of separable amide rotamers, by using Pd chemistry, and their thermodynamic behavior.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20090101

• Inapplicability of small-polaron model for the explanation of infrared absorption spectrum in acetanilide.

  Electromagnetic biology and medicine 20090101

• Nutrient enrichment and food web composition affect ecosystem metabolism in an experimental seagrass habitat.

  PloS one 20090101

• Stability-indicating simultaneous determination of paracetamol and three of its related substances using a direct GC/MS method.

  Journal of AOAC International 20090101

• Oligo(N-aryl glycines): a new twist on structured peptoids.

  Journal of the American Chemical Society 20081210

• Recent improvements in the development of A(2B) adenosine receptor agonists.

  Purinergic signalling 20081201

• Purification, molecular cloning, heterologous expression and characterization of pig CYP1A2.

  Xenobiotica; the fate of foreign compounds in biological systems 20081201

• Synthesis and evaluation of 2-substituted-6-phenyl-4,5-dihydropyridazin-3(2H)-ones as potent inodilators.

  Acta pharmaceutica (Zagreb, Croatia) 20081201

• H-bonded complexes of aniline with HF/F- and anilide with HF in terms of symmetry-adapted perturbation, atoms in molecules, and natural bond orbitals theories.

  The journal of physical chemistry. A 20081009

• A review of the immunotoxicity of the pesticide 3,4-dichloropropionanalide.

  Journal of toxicology and environmental health. Part B, Critical reviews 20081001

• New practical algorithm for modelling analyte recovery in bioanalytical reversed phase and mixed-mode solid phase extraction.

  Journal of pharmaceutical and biomedical analysis 20080910

• Testing the optimal defence hypothesis for two indirect defences: extrafloral nectar and volatile organic compounds.

  Planta 20080801

• Acetanilide mediated reversible assembly and disassembly of Au nanoparticles.

  Journal of colloid and interface science 20080801

• Selective detection of uric acid in the presence of ascorbic acid at physiological pH by using a beta-cyclodextrin modified copolymer of sulfanilic acid and N-acetylaniline.

  Biosensors & bioelectronics 20080715

• Mixed tetraoxanes containing the acetone subunit as antimalarials.

  Bioorganic & medicinal chemistry 20080715

• Over-the-counter analgesics normalize blood glucose and body composition in mice fed a high fat diet.

  Biochemical pharmacology 20080715

• 4-(Anilino)pyrrole-2-carboxamides: Novel non-steroidal/non-anilide type androgen antagonists effective upon human prostate tumor LNCaP cells with mutated nuclear androgen receptor.

  Bioorganic & medicinal chemistry 20080715

• Chloridobis{N-[(dimethyl-amino)dimethyl-silyl]-2,6-dimethyl-anilido-κN,N'}iron(III).

  Acta crystallographica. Section E, Structure reports online 20080701

• Fate of anilide and aniline herbicides in plant-materials-amended soils.

  Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20080601

• Isotope-coded, iodoacetamide-based reagent to determine individual cysteine pK(a) values by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

  Analytical biochemistry 20080415

• Characterization of acetanilide herbicides degrading bacteria isolated from tea garden soil.

  Microbial ecology 20080401

• Geometry and bond-length alternation in nonlinear optical materials. II. Effects of donor strength in two push-pull molecules.

  Acta crystallographica. Section C, Crystal structure communications 20080401

• Efficacy and tolerability of lumiracoxib, a highly selective cyclo-oxygenase-2 (COX2) inhibitor, in the management of pain and osteoarthritis.

  Therapeutics and clinical risk management 20080401

• Influence of position and size of substituents on the mechanism of partitioning: a thermodynamic study on acetaminophens, hydroxybenzoic acids, and parabens.

  AAPS PharmSciTech 20080301

• Interventions for relieving the pain and discomfort of screening mammography.

  The Cochrane database of systematic reviews 20080123

• Photoresponsive rolling and bending of thin crystals of chiral diarylethenes.

  Chemical communications (Cambridge, England) 20080121

• Pesticides in rain in four agricultural watersheds in the United States.

  Journal of environmental quality 20080101

• Chemical basis for the phytotoxicity of N-aryl hydroxamic acids and acetanilide analogues.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101

• [Effect of diet overloaded by fats on the enzyme systems of metabolism in rats].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20080101

• Effect of benthic boundary layer transport on the productivity of Mono Lake, California.

  Saline systems 20080101

• Decadal-scale changes of pesticides in ground water of the United States, 1993-2003.

  Journal of environmental quality 20080101

• Inhibitory effect of some acetyl esters and acetamides on glycation of the histone H1.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101

• Synthesis of diarylamines catalyzed by iron salts.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• The RAS/mitogen activated protein (MAP) kinase pathway in melanoma biology and therapeutics.

  Biologics : targets & therapy 20071201

• Structure-based design and synthesis of (5-arylamino-2H-pyrazol-3-yl)-biphenyl-2',4'-diols as novel and potent human CHK1 inhibitors.

  Journal of medicinal chemistry 20071101

• Inducibility of AhR-regulated CYP genes by beta-naphthoflavone in the liver, lung, kidney and heart of the pig.

  Toxicology 20071030

• Computation of pKa values of substituted aniline radical cations in dimethylsulfoxide solution.

  The journal of physical chemistry. A 20071004

• Palladium-catalyzed anilide ortho-arylation and subsequent one-pot cyclization to phenanthridines.

  The Journal of organic chemistry 20070928

• Direct observation of aminyl radical intermediate during single-crystal to single-crystal photoinduced Orton rearrangement.

  The journal of physical chemistry. B 20070906

• [Determination of acetanilide herbicide residues in tea by gas chromatography-mass spectrometry with two different ionization techniques].

  Se pu = Chinese journal of chromatography 20070901

• New 2,6,9-trisubstituted adenines as adenosine receptor antagonists: a preliminary SAR profile.

  Purinergic signalling 20070901

• Design, synthesis, and in vivo SAR of a novel series of pyrazolines as potent selective androgen receptor modulators.

  Journal of medicinal chemistry 20070809

• [From willow bark to the coxibs. Development of antiphlogistic analgesics].

  Schmerz (Berlin, Germany) 20070801

• Aryl acylamidase activity of human serum albumin with o-nitrotrifluoroacetanilide as the substrate.

  Journal of enzyme inhibition and medicinal chemistry 20070801

• A meta effect in organic photochemistry? The case of SN1 reactions in methoxyphenyl derivatives.

  Journal of the American Chemical Society 20070502

• Ethynyl-linked (pyreno)pyrrole-naphthyridine and aniline-naphthyridine molecules as fluorescent sensors of guanine via multiple hydrogen bondings.

  The Journal of organic chemistry 20070105

• Relative toxicity and occurrence patterns of pesticide mixtures in streams draining agricultural watersheds dominated by corn and soybean production.

  Integrated environmental assessment and management 20070101

• Long-distance structural consequences of H-bonding. How H-bonding affects aromaticity of the ring in variously substituted aniline/anilinium/anilide complexes with bases and acids.

  Journal of chemical information and modeling 20070101

• Design and synthesis of new rofecoxib analogs as selective cyclooxygenase-2 (COX-2) inhibitors: replacement of the methanesulfonyl pharmacophore by a N-acetylsulfonamido bioisostere.

  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20070101

• [Occupational and environmental exposure to anilide and dicarboximide pesticides].

  Giornale italiano di medicina del lavoro ed ergonomia 20070101

• Design, synthesis, and biological evaluation of (E)-3-(4-methanesulfonylphenyl)-2-(aryl)acrylic acids as dual inhibitors of cyclooxygenases and lipoxygenases.

  Bioorganic & medicinal chemistry 20061201

• The important role of Bcrp (Abcg2) in the biliary excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in mice.

  Molecular pharmacology 20061201

• Evaluation of the role of multidrug resistance-associated protein (Mrp) 3 and Mrp4 in hepatic basolateral excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in Abcc3-/- and Abcc4-/- mice.

  The Journal of pharmacology and experimental therapeutics 20061201

• Glucuronidation in the chimpanzee (Pan troglodytes): studies with acetaminophen, oestradiol and morphine.

  Xenobiotica; the fate of foreign compounds in biological systems 20061201

• Rapid approach to 3,5-disubstituted 1,4-benzodiazepines via the photo-fries rearrangement of anilides.

  The Journal of organic chemistry 20061124

• A bioisosteric approach to the discovery of indole carbinol androgen receptor ligands.

  Bioorganic & medicinal chemistry letters 20061101

• Towards an understanding of the molecular mechanism of solvation of drug molecules: a thermodynamic approach by crystal lattice energy, sublimation, and solubility exemplified by paracetamol, acetanilide, and phenacetin.

  Journal of pharmaceutical sciences 20061001

• Solubility parameter of drugs for predicting the solubility profile type within a wide polarity range in solvent mixtures.

  International journal of pharmaceutics 20060914

• Nonpeptide inhibitors of measles virus entry.

  Journal of medicinal chemistry 20060824

• Physical stability of amorphous acetanilide derivatives improved by polymer excipients.

  Chemical & pharmaceutical bulletin 20060801

• Highly selective C-H functionalization/halogenation of acetanilide.

  Journal of the American Chemical Society 20060614

• The stability of the amorphous form of cefuroxime axetil in solid state.

  Journal of pharmaceutical and biomedical analysis 20060607

• The protein-binding and drug release properties of macromolecular conjugates containing daptomycin and dextran.

  International journal of pharmaceutics 20060606

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Isolation of a bacterium that degrades urethane compounds and characterization of its urethane hydrolase.

  Applied microbiology and biotechnology 20060401

• Optimization of supercritical fluid extraction of pesticide residues in soil by means of central composite design and analysis by gas chromatography-tandem mass spectrometry.

  Journal of chromatography. A 20060331

• Diastereoselective cyclization of a dithienylethene switch through single crystal confinement.

  Organic & biomolecular chemistry 20060321

• Controlling the shape and flexibility of arylamides: a combined ab initio, ab initio molecular dynamics, and classical molecular dynamics study.

  The journal of physical chemistry. B 20060302

• Discovery of novel and potent thiazoloquinazolines as selective Aurora A and B kinase inhibitors.

  Journal of medicinal chemistry 20060209

• Establishing a chromium-reactor design for measuring delta2H values of solid polyhalogenated compounds using direct elemental analysis and stable isotope ratio mass spectrometry.

  Analytical and bioanalytical chemistry 20060101

• Development of EPA method 535 for the determination of chloroacetanilide and other acetamide herbicide degradates in drinking water by solid-phase extraction and liquid chromatography/tandem mass spectrometry.

  Journal of AOAC International 20060101

• Removal of neutral chloroacetamide herbicide degradates during simulated unit processes for drinking water treatment.

  Water research 20051201

• Behavior of acetanilide herbicides in soils and the possibility of groundwater contamination.

  Bulletin of environmental contamination and toxicology 20051201

• Slow interconversion of enantiomeric conformers or atropisomers of anilide and urea derivatives of 2-substituted anilines.

  Organic & biomolecular chemistry 20050907

• Kinetic analysis of maize glutathione S-transferase I catalysing the detoxification from chloroacetanilide herbicides.

  Planta 20050901

• Multiple mechanisms are involved in the biliary excretion of acetaminophen sulfate in the rat: role of Mrp2 and Bcrp1.

  Drug metabolism and disposition: the biological fate of chemicals 20050801

• Discovery of potent anilide inhibitors against the severe acute respiratory syndrome 3CL protease.

  Journal of medicinal chemistry 20050630

• Thermodynamic study of the transfer of acetanilide and phenacetin from water to different organic solvents.

  Acta pharmaceutica (Zagreb, Croatia) 20050601

• Synthesis of structurally defined scaffolds for bivalent ligand display based on glucuronic acid anilides. The degree of tertiary amide isomerism and folding depends on the configuration of a glycosyl azide.

  The Journal of organic chemistry 20050513

• Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).

  Journal of medicinal chemistry 20050505

• Inhibition of human and rat CYP1A2 by TCDD and dioxin-like chemicals.

  Toxicological sciences : an official journal of the Society of Toxicology 20050401

• Synthesis of aryl sulfones via L-proline-promoted CuI-catalyzed coupling reaction of aryl halides with sulfinic acid salts.

  The Journal of organic chemistry 20050401

• Anion-assisted trans-cis isomerization of palladium(II) phosphine complexes containing acetanilide functionalities through hydrogen bonding interactions.

  Chemical communications (Cambridge, England) 20050328

• Assessment of pesticide contamination in soil samples from an intensive horticulture area, using ultrasonic extraction and gas chromatography-mass spectrometry.

  Talanta 20050315

• A dual-electrode approach for highly selective detection of glucose based on diffusion layer theory: experiments and simulation.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20050204

• Studies on the reactions between daptomycin and glyceraldehyde.

  International journal of pharmaceutics 20050131

• Kinetic stability of heteroleptic (beta-diketiminato) heavier alkaline-earth (Ca, Sr, Ba) amides.

  Dalton transactions (Cambridge, England : 2003) 20050121

• Safety of the methylene blue plus chloroquine combination in the treatment of uncomplicated falciparum malaria in young children of Burkina Faso [ISRCTN27290841].

  Malaria journal 20050101

• [Synthesis of two new acetanilide derivatives and their effect on the serum antioxidant vitamins (A, E, and C) and the MDA level in rats].

  Bioorganicheskaia khimiia 20050101

• Review article toxic oil syndrome: review of immune aspects of the disease.

  Journal of immunotoxicology 20050101

• [Acetaminophen].

  Nihon rinsho. Japanese journal of clinical medicine 20041201

• Synthesis and biological evaluation of 1-aryl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of cyclin-dependent kinases.

  Journal of medicinal chemistry 20041118

• High-performance liquid chromatographic method for simultaneous determination of sophoridine and matrine in rat plasma.

  Biomedical chromatography : BMC 20041101

• [Salicylanilides: still a potential antibacterially active group].

  Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20041101

• Controlling the conformation of arylamides: computational studies of intramolecular hydrogen bonds between amides and ethers or thioethers.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20041011

• Flutolanil and carboxin resistance in Coprinus cinereus conferred by a mutation in the cytochrome b560 subunit of succinate dehydrogenase complex (Complex II).

  Molecular genetics and genomics : MGG 20041001

• Nucleophilic aromatic substitution on aryl-amido ligands promoted by oxidizing osmium(IV) centers.

  Inorganic chemistry 20040920

• Molecular properties and intermolecular forces--factors balancing the effect of carbon surface chemistry in adsorption of organics from dilute aqueous solutions.

  Journal of colloid and interface science 20040701

• Orally active CCR5 antagonists as anti-HIV-1 agents 2: synthesis and biological activities of anilide derivatives containing a pyridine N-oxide moiety.

  Chemical & pharmaceutical bulletin 20040701

• Lipophilicity-related inhibition of blood platelet aggregation by nipecotic acid anilides.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040601

• Bioisosteric replacement of anilide with benzoxazole: potent and orally bioavailable antagonists of VLA-4.

  Bioorganic & medicinal chemistry letters 20040503

• Hydrogen-bonded polymer gel and its application as a temperature-sensitive drug delivery system.

  Biomaterials 20040501

• Energy of charged states in the acetanilide crystal: trapping of charge-transfer states at vacancies as a possible mechanism for optical damage.

  The Journal of chemical physics 20040415

• The effect of carbon surface chemical composition on the adsorption of acetanilide.

  Journal of colloid and interface science 20040401

• Design of N-acetyl-6-sulfo-beta-d-glucosaminide-based inhibitors of influenza virus sialidase.

  Bioorganic & medicinal chemistry 20040315

• Synthesis and structure/NMDA receptor affinity relationships of 1-substituted tetrahydro-3-benzazepines.

  Bioorganic & medicinal chemistry 20040315

• Dissipation of alachlor in cotton plant, soil and water and its bioaccumulation in fish.

  Chemosphere 20040201

• The synthesis and anticonvulsant activity of some omega-phthalimido-N-phenylacetamide and propionamide derivatives.

  Archiv der Pharmazie 20040201

• Evaluation of toxic equivalency factors for induction of cytochromes P450 CYP1A1 and CYP1A2 enzyme activity by dioxin-like compounds.

  Toxicology and applied pharmacology 20040115

• High-performance liquid chromatographic-nuclear magnetic resonance investigation of the isomerization of alachlor-ethanesulfonic acid.

  Journal of chromatography. A 20040102

• The olivacine derivative s 16020 (9-hydroxy-5,6-dimethyl-N-[2-(dimethylamino)ethyl)-6H-pyrido(4,3-B)-carbazole-1-carboxamide) induces CYP1A and its own metabolism in human hepatocytes in primary culture.

  Drug metabolism and disposition: the biological fate of chemicals 20040101

• Antipyretic therapy.

  Frontiers in bioscience : a journal and virtual library 20040101

• Quantitative determination of p-aminosalicylic acid and its degradation product m-aminophenol in pellets by ion-pair high-performance liquid chromatography applying the monolithic Chromolith Speedrod RP-18e column.

  Biomedical chromatography : BMC 20040101

• Characterization of a strain of Sphingobacterium sp. and its degradation to herbicide mefenacet.

  Journal of environmental sciences (China) 20040101

• [Effect of starvation and acetone on the enzyme systems of biotransformation and toxicity of xenobiotics--CYP2E1 substrates in rats].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20040101

• Distinct thermodynamics for the formation and cleavage of N-H bonds in aniline and ammonia. Directly-observed reductive elimination of ammonia from an isolated amido hydride complex.

  Journal of the American Chemical Society 20031112

• Novel hydroxamate and anilide derivatives as potent histone deacetylase inhibitors: synthesis and antiproliferative evaluation.

  Current medicinal chemistry 20031101

• Slow hydrogen atom self-exchange between Os(IV) anilide and Os(III) aniline complexes: relationships with electron and proton transfer self-exchange.

  Journal of the American Chemical Society 20031008

• Suitability of the cynomolgus monkey as an animal model for drug absorption studies of oral dosage forms from the viewpoint of gastrointestinal physiology.

  Biological & pharmaceutical bulletin 20031001

• Ethyl N-phenyloxamate.

  Acta crystallographica. Section C, Crystal structure communications 20031001

• [Surveillance on concurrent administration of quinolones and anti-inflammatory drugs in a community hospital].

  The Japanese journal of antibiotics 20030801

• Colorimetric reversibility of polydiacetylene supramolecules having enhanced hydrogen-bonding under thermal and pH stimuli.

  Journal of the American Chemical Society 20030730

• Examination of molecular interaction sites of acetanilides with organic matter surrogates using nuclear magnetic resonance techniques.

  Journal of agricultural and food chemistry 20030618

• Transiently altered acetaminophen metabolism after liver transplantation.

  Clinical pharmacology and therapeutics 20030601

• Unmasking tandem site interaction in human acetylcholinesterase. Substrate activation with a cationic acetanilide substrate.

  Biochemistry 20030513

• Contribution of human cytochrome p-450 isoforms to the metabolism of the simplest phenothiazine neuroleptic promazine.

  British journal of pharmacology 20030401

• The bis-barium complex of a butterfly crown ether as a phototunable supramolecular catalyst.

  Journal of the American Chemical Society 20030226

• Electrochemical and spectroscopic studies of the oxidation mechanism of the herbicide propanil.

  Journal of agricultural and food chemistry 20030212

• The mandelamide keto-enol system in aqueous solution. Generation of the enol by hydration of phenylcarbamoylcarbene.

  Journal of the American Chemical Society 20030108

• The metabolism of 2-trifluormethylaniline and its acetanilide in the rat by 19F NMR monitored enzyme hydrolysis and 1H/19F HPLC-NMR spectroscopy.

  Journal of pharmaceutical and biomedical analysis 20030101

• Metabolites of a blocked chloramphenicol producer.

  Journal of natural products 20030101

• Herbicides and herbicide degradation products in Upper Midwest agricultural streams during August base-flow conditions.

  Journal of environmental quality 20030101

• Effects of land use on ground water quality in the Anoka Sand Plain Aquifer of Minnesota.

  Ground water 20030101

• Reactions of the ionized enol tautomer of acetanilide: elimination of HNCO via a novel rearrangement.

  European journal of mass spectrometry (Chichester, England) 20030101

• Purification and characterization of rat pancreatic fatty acid ethyl ester synthase and its structural and functional relationship to pancreatic cholesterol esterase.

  Journal of biochemical and molecular toxicology 20030101

• Application of the PKCYP test to predict caffeine clearance mediated by CYP1A2 in a rat acute liver injury model.

  Drug metabolism and pharmacokinetics 20030101

• Biological activity of p-methylaminophenol, an essential structural component of N-(4-hydroxyphenyl)retinamide, fenretinide.

  Journal of biochemistry 20021101

• Introduction of a hydroxy group at the para position and N-iodophenylation of N-arylamides using phenyliodine(III) bis(trifluoroacetate).

  The Journal of organic chemistry 20021018

• Biodegradation of acetanilide herbicides acetochlor and butachlor in soil.

  Journal of environmental sciences (China) 20021001

• Influence of herbicide structure, clay acidity, and humic acid coating on acetanilide herbicide adsorption on homoionic clays.

  Journal of agricultural and food chemistry 20020703

• The metabolism of 4-trifluoromethoxyaniline and [13C]-4-trifluoromethoxyacetanilide in the rat: detection and identification of metabolites excreted in the urine by NMR and HPLC-NMR.

  Journal of pharmaceutical and biomedical analysis 20020601

• Liquid chromatographic resolution of N-acyl-alpha-amino acids as their anilide derivatives on a chiral stationary phase based on (S)-leucine.

  Chirality 20020601

• Degradation of aniline by newly isolated, extremely aniline-tolerant Delftia sp. AN3.

  Applied microbiology and biotechnology 20020401

• Identification of the urinary metabolites of 4-bromoaniline and 4-bromo-[carbonyl-13C]-acetanilide in rat.

  Xenobiotica; the fate of foreign compounds in biological systems 20020401

• Adsorption of chloroacetanilide herbicides on soil and its components. III. Influence of clay acidity, humic acid coating and herbicide structure on acetanilide herbicide adsorption on homoionic clays.

  Journal of environmental sciences (China) 20020401

• Iodine(V) reagents in organic synthesis. Part 3. New routes to heterocyclic compounds via o-iodoxybenzoic acid-mediated cyclizations: generality, scope, and mechanism.

  Journal of the American Chemical Society 20020313

• Selective Pd-catalyzed oxidative coupling of anilides with olefins through C-H bond activation at room temperature.

  Journal of the American Chemical Society 20020227

• Femtosecond study of self-trapped vibrational excitons in crystalline acetanilide.

  Physical review letters 20020211

• Effect of alachlor on hepatic cytochrome P450 enzymes in rats.

  Drug and chemical toxicology 20020201

• Size-selective catalysis of ester and anilide cleavage by the dinuclear barium(II) complexes of cis- and trans-stilbenobis(18-crown-6).

  The Journal of organic chemistry 20020125

• Rational determination of transfer free energies of small drugs across the water-oil interface.

  Journal of medicinal chemistry 20020103

• Determination of crude protein in animal feed, forage, grain, and oilseeds by using block digestion with a copper catalyst and steam distillation into boric acid: collaborative study.

  Journal of AOAC International 20020101

• [Interaction of local anesthetics with model ion channels].

  Biofizika 20020101

• Novel chromatographic separation and carbon solid-phase extraction of acetanilide herbicide degradation products.

  Journal of AOAC International 20020101

• 1H-NMR assay of papaverine hydrochloride and formulations.

  Phytochemical analysis : PCA 20020101

• Interventions for relieving the pain and discomfort of screening mammography.

  The Cochrane database of systematic reviews 20020101

• Perazine as a potent inhibitor of human CYP1A2 but not CYP3A4.

  Polish journal of pharmacology 20020101

• Stabilization of the hydrophilic sphere of non-ionic monomers: are all protected in a similar way?

  The British journal of radiology 20011201

• Nonlinear free energy relationship in the general-acid-catalyzed acylation of rat kidney gamma-glutamyl transpeptidase by a series of gamma-glutamyl anilide substrate analogues.

  Biochemistry 20011023

• Application of the PKCYP-test in cases of altered CYP1A2 for multiple CYP systems in rat models of disease.

  Biological & pharmaceutical bulletin 20010901

• Cloning, sequence analysis, and characterization of the astA gene encoding an arylsulfate sulfotransferase from Citrobacter freundii.

  Archives of pharmacal research 20010801

• Research strategies for design and development of NSAIDs: clue to balance potency and toxicity of acetanilide compounds.

  Journal of biomolecular structure & dynamics 20010801

• Redox-induced terpyridyl substitution in the Os(VI)-hydrazido complex, trans-[Os(VI)(tpy)(Cl)(2)(NN(CH(2))(4)O)](2+).

  Inorganic chemistry 20010730

• Immune thrombocytopenia resulting from sensitivity to metabolites of naproxen and acetaminophen.

  Blood 20010615

• A long-term lifetime amperometric glucose sensor with a perfluorocarbon polymer coating.

  Biosensors & bioelectronics 20010601

• Synthesis of tricyclic indole-2-carboxylic [correction of caboxylic] acids as potent NMDA-glycine antagonists.

  The Journal of organic chemistry 20010518

• Acyl substitution at the ortho position of anilides enhances oral bioavailability of thiophene sulfonamides: TBC3214, an ETA selective endothelin antagonist.

  Journal of medicinal chemistry 20010412

• The utilization of aniline, chlorinated aniline, and aniline blue as the only source of nitrogen by fungi in water.

  Water research 20010401

• Adsorption of acetanilide herbicides on soil and its components. II. Adsorption and catalytic hydrolysis of diethatyl-ethyl on saturated Na(+)-, K(+)-, Ca(2+)-, and Mg(2+)-montmorillonite.

  Journal of environmental sciences (China) 20010401

• Experimental and theoretical microdialysis studies of in situ metabolism.

  Analytical biochemistry 20010301

• Substitutions of Thr-103-Ile and Trp-138-Gly in amidase from Pseudomonas aeruginosa are responsible for altered kinetic properties and enzyme instability.

  Molecular biotechnology 20010301

• Evaluation of the toxicity of substituted benzthioanilides by using in vitro tests.

  Alternatives to laboratory animals : ATLA 20010101

• [Various mechanisms of the depriming effect of bacterial endotoxin on drug metabolism].

  Eksperimental'naia i klinicheskaia farmakologiia 20010101

• Characterization of two novel propachlor degradation pathways in two species of soil bacteria.

  Applied and environmental microbiology 19990201

• Acetanilide oxidation in phenylbutazone-associated hypoplastic anaemia.

  British medical journal 19740803