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Home  > 2-Methyl-5-trifluoromethylphenylboronic acid, pinacol ester

AE25175

1030832-71-3 | 2-Methyl-5-trifluoromethylphenylboronic acid, pinacol ester

Packsize Purity Availability Price Discounted Price    Quantity
100mg 97% in stock $39.00 $27.00 -   +
250mg 97% in stock $48.00 $33.00 -   +
1g 97% in stock $58.00 $40.00 -   +
5g 97% in stock $175.00 $122.00 -   +
25g 97% in stock $851.00 $596.00 -   +

*All products are for research use only and not intended for human or animal use.

*All prices are in USD.

Description
Catalog Number: AE25175
Chemical Name: 2-Methyl-5-trifluoromethylphenylboronic acid, pinacol ester
CAS Number: 1030832-71-3
Molecular Formula: C14H18BF3O2
Molecular Weight: 286.0977
MDL Number: MFCD18729902
SMILES: FC(c1ccc(c(c1)B1OC(C(O1)(C)C)(C)C)C)(F)F

 

Upstream Synthesis Route
  • 2-Methyl-5-trifluoroMethylphenylboronic acid, pinacol ester is a versatile reagent commonly used in chemical synthesis as a key building block in organic reactions. This compound serves as an important source of the 2-methyl-5-trifluoromethylphenylboron group, which can be easily transferred to various substrates for functionalization. Its unique structure and reactivity make it valuable in a wide range of synthetic applications.One of the primary uses of 2-Methyl-5-trifluoroMethylphenylboronic acid, pinacol ester is in cross-coupling reactions, particularly in Suzuki-Miyaura coupling reactions with aryl halides or pseudohalides. This reagent enables the efficient formation of carbon-carbon bonds, allowing for the synthesis of complex organic molecules. Additionally, the trifluoromethyl group can impart unique properties to the final products, making them valuable in medicinal chemistry and materials science.Furthermore, this compound can also be employed in the preparation of heterocyclic compounds, which are key structural motifs in pharmaceuticals and natural products. The boronic acid functionality can participate in various transformations, such as oxidation, reduction, and nucleophilic addition reactions, expanding the synthetic utility of this reagent.Overall, the application of 2-Methyl-5-trifluoroMethylphenylboronic acid, pinacol ester in chemical synthesis offers chemists a powerful tool for the construction of diverse molecules with strategic functional groups, making it an indispensable reagent in organic synthesis.
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