1032758-88-5 | 2-(tert-Butoxycarbonylamino)pyrimidine-5-boronic acid, pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$66.00	$46.00
250mg	98%	in stock	$99.00	$69.00
1g	98%	in stock	$215.00	$150.00
5g	98%	in stock	$750.00	$525.00
25g	98%	in stock	$3,089.00	$2,162.00

Description

• Catalog Number: AD80705
• Chemical Name: 2-(tert-Butoxycarbonylamino)pyrimidine-5-boronic acid, pinacol ester
• CAS Number: 1032758-88-5
• Molecular Formula: C15H24BN3O4
• Molecular Weight: 321.1798
• MDL Number: MFCD09027069
• SMILES: O=C(OC(C)(C)C)Nc1ncc(cn1)B1OC(C(O1)(C)C)(C)C

Computed Properties

• Complexity: 427
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 23
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 4

Upstream Synthesis Route

The tert-Butyl (5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)carbamate is a versatile compound used in chemical synthesis for its unique reactivity and selectivity. It serves as a valuable reagent in various organic transformations, particularly in cross-coupling reactions and palladium-catalyzed coupling reactions.This compound is commonly employed as a protecting group for amines due to its stability under various reaction conditions. It allows for the selective modification of molecules by masking the amine functionality and enabling specific transformations to occur at other reactive sites. Additionally, the presence of the boronate ester moiety in the molecule enhances its utility in Suzuki-Miyaura cross-coupling reactions, facilitating the formation of C-C bonds in a controlled manner.Moreover, the tert-Butyl (5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)carbamate exhibits excellent solubility in common organic solvents, making it convenient for use in various synthetic protocols. Its compatibility with a wide range of reaction conditions and functional groups further enhances its value as a strategic building block for complex molecule synthesis in medicinal chemistry and material science.