104113-71-5 | 1-(Naphth-1-yl)piperazine diHCl

Packsize	Purity	Availability	Price	Discounted Price
250mg		in stock	$60.00	$42.00

Description

• Catalog Number: AI06281
• Chemical Name: 1-(Naphth-1-yl)piperazine diHCl
• CAS Number: 104113-71-5
• Molecular Formula: C14H17ClN2
• Molecular Weight: 248.7512
• MDL Number: MFCD00055161
• SMILES: N1CCN(CC1)c1cccc2c1cccc2.Cl

Computed Properties

• Complexity: 223
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1

Upstream Synthesis Route

Piperazine, 1-(1-naphthalenyl)-, monohydrochloride is a versatile chemical compound commonly used in chemical synthesis processes. This compound serves as an important building block in the creation of various pharmaceuticals, agrochemicals, and specialty chemicals. Its unique chemical structure allows for a wide range of functionalization reactions, making it a valuable tool in organic synthesis.In chemical synthesis, Piperazine, 1-(1-naphthalenyl)-, monohydrochloride is often utilized as a key intermediate in the production of heterocyclic compounds and complex organic molecules. It plays a crucial role in the formation of new chemical entities with diverse properties and applications. The compound's presence in a synthesis pathway can influence the selectivity, yield, and overall efficiency of the reaction, making it a sought-after reagent in the field of organic chemistry.Researchers and chemists rely on Piperazine, 1-(1-naphthalenyl)-, monohydrochloride for its ability to facilitate the construction of intricate molecular architectures and functional groups. Its incorporation into multi-step synthesis protocols allows for the creation of structurally complex compounds with tailored properties. By harnessing the reactivity of this compound, chemists can access a wide array of chemical structures for further investigation and development.Overall, Piperazine, 1-(1-naphthalenyl)-, monohydrochloride is a valuable tool in chemical synthesis, enabling the construction of diverse compounds with potential applications in pharmaceuticals, materials science, and beyond. Its versatility and utility make it a favored choice for chemists seeking to explore new pathways and methodologies in organic synthesis.

Literature

• Agents that reverse UV-Induced immune suppression and photocarcinogenesis affect DNA repair.

  The Journal of investigative dermatology 20100501

• Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

  Nature chemical biology 20091001

• Increased serotonergic functions following adminstration of 1-(1-naphthyl) piperazine in propranolol injected rats.

  Pakistan journal of pharmaceutical sciences 20060701

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• 1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands.

  Bioorganic & medicinal chemistry letters 20050315

• 1-(1-naphthyl)-piperazine, a mixed 5-HT1A and 5-HT2A/2C receptor ligand, elicits an anxiolytic-like effect in the open-field test without changes in 5-HT metabolism.

  Methods and findings in experimental and clinical pharmacology 20020401

• Pre- and postsynaptic responses to 1-(1-naphthylpiperazine) following adaptation to stress in rats.

  Progress in neuro-psychopharmacology & biological psychiatry 20020101

• 5-HT1B receptor antagonist properties of novel arylpiperazide derivatives of 1-naphthylpiperazine.

  Journal of medicinal chemistry 19971121