10522-47-1 | 5-Bromo-8-methoxyquinoline

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$18.00	$13.00
1g	98%	in stock	$44.00	$31.00
5g	98%	in stock	$138.00	$97.00
10g	98%	in stock	$259.00	$182.00
100g	98%	in stock	$1,879.00	$1,316.00

Description

• Catalog Number: AD69060
• Chemical Name: 5-Bromo-8-methoxyquinoline
• CAS Number: 10522-47-1
• Molecular Formula: C10H8BrNO
• Molecular Weight: 238.0806
• MDL Number: MFCD04966996
• SMILES: COc1ccc(c2c1nccc2)Br

Computed Properties

• Complexity: 176
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 3.1

Upstream Synthesis Route

5-Bromo-8-methoxyquinoline is a versatile compound that finds extensive application in chemical synthesis. Due to its unique structure and reactivity, this compound is widely used as a building block in the synthesis of various organic molecules and pharmaceutical intermediates. Its bromine and methoxy functional groups allow for specific modifications and derivatization, making it a valuable tool in the creation of novel compounds.In organic synthesis, 5-Bromo-8-methoxyquinoline serves as a key intermediate in the preparation of a variety of heterocyclic compounds, including quinoline derivatives and biologically active molecules. Its presence in the synthesis pathway enables the introduction of specific functional groups at strategic positions, enhancing the desired properties of the final product. Additionally, the bromine atom provides a handle for further transformations, such as metal-catalyzed cross-coupling reactions, facilitating the creation of complex molecular structures.Furthermore, the methoxy group in 5-Bromo-8-methoxyquinoline can act as a directing group in transition metal-catalyzed reactions, guiding regioselective bond formations and enhancing the efficiency of the synthetic process. This compound's ability to participate in diverse chemical reactions and its compatibility with various synthetic methodologies make it an indispensable component in the toolbox of organic chemists and medicinal chemists alike.