1062295-85-5 | 5-Cyclopropyl-3-(trifluoromethyl)-1H-pyrazole

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$113.00	$79.00
5g	97%	in stock	$393.00	$275.00
25g	97%	in stock	$1,535.00	$1,074.00

Description

• Catalog Number: AV38849
• Chemical Name: 5-Cyclopropyl-3-(trifluoromethyl)-1H-pyrazole
• CAS Number: 1062295-85-5
• Molecular Formula: C7H7F3N2
• Molecular Weight: 176.1391
• MDL Number: MFCD03422575
• SMILES: FC(c1n[nH]c(c1)C1CC1)(F)F

Computed Properties

• Complexity: 176
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 1.7

Upstream Synthesis Route

5-cyclopropyl-3-(trifluoromethyl)-1H-pyrazole is a versatile building block in chemical synthesis due to its unique structural features. It serves as a valuable intermediate in the pharmaceutical and agrochemical industries, where its cyclopropyl and trifluoromethyl groups confer desirable properties to the final products.In organic synthesis, 5-cyclopropyl-3-(trifluoromethyl)-1H-pyrazole is commonly used as a key starting material for the preparation of diverse functionalized compounds. The cyclopropyl ring provides rigidity and steric effects, influencing the overall molecular conformation and properties. Meanwhile, the trifluoromethyl group imparts lipophilicity and electron-withdrawing characteristics, enhancing the bioavailability and pharmacokinetic profiles of the target molecules.This compound finds applications in the synthesis of bioactive molecules, such as pharmaceutical drugs and crop protection agents. By strategically incorporating 5-cyclopropyl-3-(trifluoromethyl)-1H-pyrazole into chemical structures, chemists can modulate the reactivity, selectivity, and biological activities of the final products. Its presence can lead to improved efficacy, reduced toxicity, and enhanced metabolic stability, making it a valuable tool in medicinal and agricultural chemistry.