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Rufinamide, an antiepileptic drug, improves cognition and increases neurogenesis in the aged gerbil hippocampal dentate gyrus via increasing expressions of IGF-1, IGF-1R and p-CREB.
Chemico-biological interactions 20180425
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Rufinamide efficacy and safety as adjunctive treatment in children with focal drug resistant epilepsy: the first Italian prospective study.
Epilepsy research 20121101
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Rufinamide in children with refractory epilepsy: pharmacokinetics, efficacy, and safety.
Neuropediatrics 20121001
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First long-term experience with the orphan drug rufinamide in children with myoclonic-astatic epilepsy (Doose syndrome).
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20120901
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Chemical properties of antiepileptic drugs (AEDs).
Advanced drug delivery reviews 20120701
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Recent and future antiepileptic drugs and their impact on cognition: what can we expect?
Expert review of neurotherapeutics 20120601
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Drug-induced QT-interval shortening following antiepileptic treatment with oral rufinamide.
Heart rhythm 20120501
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Rufinamide as an adjuvant treatment in children with Lennox-Gastaut syndrome.
Seizure 20120501
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Rufinamide: a pharmacoeconomic profile of its use as adjunctive therapy in Lennox-Gastaut syndrome.
PharmacoEconomics 20120301
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[Therapeutic drug monitoring of rufinamide].
Therapie 20120101
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Investigation of the metabolism of rufinamide and its interaction with valproate.
Drug metabolism letters 20111201
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Development and validation of an HPLC-UV detection assay for the determination of rufinamide in human plasma and saliva.
Analytical and bioanalytical chemistry 20110801
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Low long-term efficacy and tolerability of add-on rufinamide in patients with Dravet syndrome.
Epilepsy & behavior : E&B 20110701
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Efficacy of rufinamide in drug-resistant epilepsy: a meta-analysis.
Pediatric neurology 20110501
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Rufinamide from clinical trials to clinical practice in the United States and Europe.
Epileptic disorders : international epilepsy journal with videotape 20110501
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New and forthcoming anti-epileptic drugs.
Current opinion in neurology 20110401
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Rufinamide for the treatment of Lennox-Gastaut syndrome.
Expert opinion on pharmacotherapy 20110401
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Rufinamide for pediatric patients with Lennox-Gastaut syndrome: a comprehensive overview.
Paediatric drugs 20110401
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Management of seizures in Lennox-Gastaut syndrome.
Paediatric drugs 20110401
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Serum concentrations of rufinamide in children and adults with epilepsy: the influence of dose, age, and comedication.
Therapeutic drug monitoring 20110401
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Methyl 1-(2,6-difluoro-benz-yl)-1H-1,2,3-triazole-4-carboxyl-ate.
Acta crystallographica. Section E, Structure reports online 20110401
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Treatment of malignant migrating partial epilepsy of infancy with rufinamide: report of five cases.
Epileptic disorders : international epilepsy journal with videotape 20110301
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Rufinamide in refractory childhood epileptic encephalopathies other than Lennox-Gastaut syndrome.
European journal of neurology 20110201
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A randomized, double-blind, placebo-controlled, parallel-group study of rufinamide as adjunctive therapy for refractory partial-onset seizures.
Epilepsia 20110201
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Activation of suicidal ideation with adjunctive rufinamide in bipolar disorder.
Epilepsy & behavior : E&B 20110201
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Rufinamide for the treatment of epileptic spasms.
Epilepsy & behavior : E&B 20110201
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Pharmacotherapy of epilepsy: newly approved and developmental agents.
CNS drugs 20110201
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Refractory focal epilepsy in a patient with methylmalonic aciduria: case report on positive and long-lasting effect of rufinamide.
Neuropediatrics 20110201
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Epilepsy with myoclonic absences - favourable response to add-on rufinamide treatment in 3 cases.
Neuropediatrics 20110201
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[Lennox-Gastaut syndrome--course and treatment].
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20110107
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Rapid assay of rufinamide in dried blood spots by a new liquid chromatography-tandem mass spectrometric method.
Journal of pharmaceutical and biomedical analysis 20110105
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Rufinamide for refractory epilepsy in a pediatric and young adult population.
Epilepsy research 20110101
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Bioavailability of three rufinamide oral suspensions compared with the marketed 400-mg tablet formulation: results from a randomized-sequence, open-label, four-period, four-sequence crossover study in healthy subjects.
Clinical therapeutics 20110101
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Ethyl 1-(2,6-difluoro-benz-yl)-1H-1,2,3-triazole-4-carboxyl-ate.
Acta crystallographica. Section E, Structure reports online 20110101
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Update on rufinamide in childhood epilepsy.
Neuropsychiatric disease and treatment 20110101
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Clobazam as an adjunctive therapy in treating seizures associated with Lennox-Gastaut syndrome.
Neuropsychiatric disease and treatment 20110101
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Post-treatment with voltage-gated Na(+) channel blocker attenuates kainic acid-induced apoptosis in rat primary hippocampal neurons.
Neurochemical research 20101201
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New drugs for pediatric epilepsy.
Seminars in pediatric neurology 20101201
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'Epileptic encephalopathy' of infancy and childhood: electro-clinical pictures and recent understandings.
Current neuropharmacology 20101201
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Rufinamide in children and adults with Lennox-Gastaut syndrome: first Italian multicenter experience.
Seizure 20101101
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Adjunctive rufinamide in Lennox-Gastaut syndrome: a long-term, open-label extension study.
Acta neurologica Scandinavica 20100901
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Emerging drugs for partial onset seizures.
Expert opinion on emerging drugs 20100901
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Experience with rufinamide in a pediatric population: a single center's experience.
Pediatric neurology 20100901
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Antiepileptic drug interactions - principles and clinical implications.
Current neuropharmacology 20100901
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Update on anticonvulsant drugs.
Current neurology and neuroscience reports 20100701
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New antiepileptic drugs: lacosamide, rufinamide, and vigabatrin.
Current treatment options in neurology 20100701
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Rufinamide: a new antiepileptic drug treatment for Lennox-Gastaut syndrome.
Expert review of neurotherapeutics 20100601
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Medical management of Lennox-Gastaut syndrome.
CNS drugs 20100501
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[Antiepileptic drugs in North America].
Brain and nerve = Shinkei kenkyu no shinpo 20100501
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Severe constipation associated with the use of rufinamide (Banzel) in an adolescent.
Epilepsy & behavior : E&B 20100501
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First European long-term experience with the orphan drug rufinamide in childhood-onset refractory epilepsy.
Epilepsy & behavior : E&B 20100401
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Rufinamide: a new antiepileptic medication for the treatment of seizures associated with lennox-gastaut syndrome.
The Annals of pharmacotherapy 20100401
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Gateways to clinical trials.
Methods and findings in experimental and clinical pharmacology 20100401
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Recent advances in adjunctive therapy for epilepsy: focus on sodium channel blockers as third-generation antiepileptic drugs.
Drugs of today (Barcelona, Spain : 1998) 20100401
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Stability of extemporaneously prepared rufinamide oral suspensions.
The Annals of pharmacotherapy 20100301
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Gateways to clinical trials.
Methods and findings in experimental and clinical pharmacology 20100301
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Simultaneous HPLC-UV analysis of rufinamide, zonisamide, lamotrigine, oxcarbazepine monohydroxy derivative and felbamate in deproteinized plasma of patients with epilepsy.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100201
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A 24-week multicenter, randomized, double-blind, parallel-group, dose-ranging study of rufinamide in adults and adolescents with inadequately controlled partial seizures.
Epilepsy research 20100201
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Nursing 20100201
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Supporting the recommended paediatric dosing regimen for rufinamide in Lennox-Gastaut syndrome using clinical trial simulation.
Journal of pharmacokinetics and pharmacodynamics 20100201
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Drug-induced QT interval shortening: potential harbinger of proarrhythmia and regulatory perspectives.
British journal of pharmacology 20100101
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Cost-utility analysis of rufinamide versus topiramate and lamotrigine for the treatment of children with Lennox-Gastaut Syndrome in the United Kingdom.
Seizure 20100101
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Drug interactions involving the new second- and third-generation antiepileptic drugs.
Expert review of neurotherapeutics 20100101
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Rufinamide: a novel broad-spectrum antiepileptic drug.
Epilepsy currents 20100101
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The cost effectiveness of rufinamide in the treatment of Lennox-Gastaut syndrome in the UK.
PharmacoEconomics 20100101
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The possible antianxiety and mood-stabilizing effects of rufinamide.
Psychotherapy and psychosomatics 20100101
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Treating Lennox-Gastaut syndrome in epileptic pediatric patients with third-generation rufinamide.
Neuropsychiatric disease and treatment 20100101
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Journal of pediatric neurosciences 20100101
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Expression, regulation and function of phosphofructo-kinase/fructose-biphosphatases (PFKFBs) in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia cells.
BMC cancer 20100101
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Selected pharmacokinetic issues of the use of antiepileptic drugs and parenteral nutrition in critically ill patients.
Nutrition journal 20100101
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Safety and tolerability of rufinamide in children with epilepsy: a pooled analysis of 7 clinical studies.
Journal of child neurology 20091201
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Treatment of Lennox-Gastaut Syndrome (LGS).
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20091101
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Gateways to clinical trials.
Methods and findings in experimental and clinical pharmacology 20091101
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Rufinamide for the adjunctive treatment of partial seizures in adults and adolescents: a randomized placebo-controlled trial.
Epilepsia 20090801
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The Cochrane database of systematic reviews 20090708
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Antiepileptic drug monotherapy: the initial approach in epilepsy management.
Current neuropharmacology 20090601
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Current neuropharmacology 20090601
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Truly 'rational' polytherapy: maximizing efficacy and minimizing drug interactions, drug load, and adverse effects.
Current neuropharmacology 20090601
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Minimizing AED adverse effects: improving quality of life in the interictal state in epilepsy care.
Current neuropharmacology 20090601
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Adopting an orphan drug: rufinamide for Lennox-Gastaut syndrome.
Epilepsy currents 20090501
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Rufinamide (Banzel) for epilepsy.
The Medical letter on drugs and therapeutics 20090309
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Effectiveness and tolerability of rufinamide in children and adults with refractory epilepsy: first European experience.
Epilepsy & behavior : E&B 20090301
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American Epilepsy Society--62nd Annual Meeting. 5-9 December 2008, Seattle, USA.
IDrugs : the investigational drugs journal 20090201
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Product: Banzel.
JAAPA : official journal of the American Academy of Physician Assistants 20090201
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New drugs: Febuxostat, lacosamide, and rufinamide.
Journal of the American Pharmacists Association : JAPhA 20090101
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Third-generation antiepileptic drugs: mechanisms of action, pharmacokinetics and interactions.
Pharmacological reports : PR 20090101
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Onset of action and seizure control in Lennox-Gaustaut syndrome: focus on rufinamide.
Therapeutics and clinical risk management 20090101
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Update on the management of Lennox-Gastaut syndrome with a focus on rufinamide.
Neuropsychiatric disease and treatment 20090101
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Treatment of Lennox-Gastaut syndrome: overview and recent findings.
Neuropsychiatric disease and treatment 20081201
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Neuropsychiatric disease and treatment 20081201
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Revista de neurologia 20081001
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Prescrire international 20080801
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Epilepsia 20080701
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Epilepsia 20080701
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Medizinische Monatsschrift fur Pharmazeuten 20071001
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Expert opinion on pharmacotherapy 20070801
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Drugs of today (Barcelona, Spain : 1998) 20070701
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The Journal of pharmacy and pharmacology 20070501
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[A new aspect in the research on antiepileptic drugs].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20070201
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Neuropsychiatric disease and treatment 20070201
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Epilepsy research 20070101
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International journal of clinical practice 20061101
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Methods and findings in experimental and clinical pharmacology 20061001
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Gateways to clinical trials.
Methods and findings in experimental and clinical pharmacology 20060901
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Epilepsia 20060701
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Epilepsy research 20060601
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New antiepileptic drugs that are second generation to existing antiepileptic drugs.
Expert opinion on investigational drugs 20060601
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Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
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Gateways to clinical trials.
Methods and findings in experimental and clinical pharmacology 20060101
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CNS drugs 20060101
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Drugs in R&D 20050101
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Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
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Practice of solid-phase extraction and protein precipitation in the 96-well format combined with high-performance liquid chromatography-ultraviolet detection for the analysis of drugs in plasma and brain.
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Rufinamide: a double-blind, placebo-controlled proof of principle trial in patients with epilepsy.
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