1072-83-9 | 2-Acetylpyrrole

Packsize	Purity	Availability	Price	Discounted Price
10g	98%	in stock	$12.00	$8.00
25g	98%	in stock	$21.00	$15.00
100g	98%	in stock	$52.00	$36.00

Description

• Catalog Number: AB60890
• Chemical Name: 2-Acetylpyrrole
• CAS Number: 1072-83-9
• Molecular Formula: C6H7NO
• Molecular Weight: 109.1259
• MDL Number: MFCD00005220
• SMILES: CC(=O)c1ccc[nH]1
• NSC Number: 42861

Computed Properties

• Complexity: 101
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 0.9

Upstream Synthesis Route

1-(1H-Pyrrol-2-yl)ethanone, commonly known as pyrrole-2-acetone, is a versatile compound widely utilized in chemical synthesis. This ketone derivative plays a crucial role in various organic reactions, offering unique properties that make it a valuable building block in the production of a wide range of chemical compounds.For instance, one of the key applications of 1-(1H-Pyrrol-2-yl)ethanone is in the synthesis of heterocyclic compounds. By introducing this molecule into reactions, chemists can efficiently create complex structures with diverse functionalities. The presence of the pyrrole ring provides aromatic character and electron-rich properties, making it a useful component in the construction of pharmaceuticals, agrochemicals, and materials with specific properties.Furthermore, the carbonyl group in 1-(1H-Pyrrol-2-yl)ethanone enables it to participate in various organic transformations, such as nucleophilic addition reactions and condensation reactions. This reactivity allows for the incorporation of this compound into multi-step synthesis routes, leading to the formation of novel molecules with tailored properties.Overall, the application of 1-(1H-Pyrrol-2-yl)ethanone in chemical synthesis showcases its significance as a key intermediate in the creation of diverse organic compounds, highlighting its utility and versatility in modern synthetic chemistry.

Literature

• Antioxidant activities of extracts from teas prepared from medicinal plants, Morus alba L., Camellia sinensis L., and Cudrania tricuspidata , and their volatile components.

  Journal of agricultural and food chemistry 20120912

• Direct functionalization of (un)protected tetrahydroisoquinoline and isochroman under iron and copper catalysis: two metals, two mechanisms.

  The Journal of organic chemistry 20111104

• Key aroma components of a dry-cured sausage with high fat content (sobrassada).

  Food science and technology international = Ciencia y tecnologia de los alimentos internacional 20110201

• Changes in volatile compounds upon aging and drying in oolong tea production.

  Journal of the science of food and agriculture 20110130

• Identification of hydroxycinnamic acid-maillard reaction products in low-moisture baking model systems.

  Journal of agricultural and food chemistry 20091111

• Role of roasting conditions in the profile of volatile flavor chemicals formed from coffee beans.

  Journal of agricultural and food chemistry 20090708

• 2- and 3-acetylpyrroles: a combined calorimetric and computational study.

  The journal of physical chemistry. A 20090416

• 3-(4-Methoxy-phen-yl)-1-(2-pyrrol-yl)prop-2-en-1-one.

  Acta crystallographica. Section E, Structure reports online 20081001

• 3-[4-(Dimethyl-amino)phen-yl]-1-(2-pyrrol-yl)prop-2-en-1-one.

  Acta crystallographica. Section E, Structure reports online 20080601

• (2E)-3-(4-Chloro-phen-yl)-1-(1H-pyrrol-2-yl)prop-2-en-1-one.

  Acta crystallographica. Section E, Structure reports online 20080501

• Chlorido{2-[1-(2-pyridylmethyl-imino)eth-yl]pyrrolato-κN,N',N''}copper(II).

  Acta crystallographica. Section E, Structure reports online 20080401

• Bis(ketopyrrolyl) complexes of Co(II) stabilised by trimethylphosphine ligands.

  Dalton transactions (Cambridge, England : 2003) 20071214

• Influence of epicatechin reactions on the mechanisms of Maillard product formation in low moisture model systems.

  Journal of agricultural and food chemistry 20070124

• Synthesis, spectroscopic, and antimicrobial studies on bivalent nickel and copper complexes of bis(thiosemicrbazone).

  Bioinorganic chemistry and applications 20070101

• Characterisation of glycoprotein ligands synthesised using solid-phase combinatorial chemistry.

  Journal of chromatography. A 20050520

• Aroma compounds in sweet whey powder.

  Journal of dairy science 20041201

• Synthesis of novel dihydropyridine, dihydropyrimidine, dithioacetal and chalcone derivatives from formylchromones.

  Bollettino chimico farmaceutico 20040301

• Effect of the pyrrole polymerization mechanism on the antioxidative activity of nonenzymatic browning reactions.

  Journal of agricultural and food chemistry 20030910

• Pyrrole alkaloids from Bolbostemma paniculatum.

  Journal of Asian natural products research 20030901

• Thermal decomposition of specifically phosphorylated D-glucoses and their role in the control of the Maillard reaction.

  Journal of agricultural and food chemistry 20030521

• 1-(2-Pyridyl) ethan-1-one 8-quinolylhydrazone and 1-(1H-pyrrol-2-yl) ethan-1-one 8-quinolylhydrazone.

  Acta crystallographica. Section C, Crystal structure communications 20021101

• Antioxidative activity of heterocyclic compounds found in coffee volatiles produced by Maillard reaction.

  Journal of agricultural and food chemistry 20020911

• Selective cleavage of P-N bonds and the conversion of rhodium N-pyrrolyl phosphine complexes into diphosphoxane-bridged dimers.

  Inorganic chemistry 20020408

• Aging of proteins: immunological detection of a glucose-derived pyrrole formed during maillard reaction in vivo.

  The Journal of biological chemistry 19890305