1073338-92-7 | 5-(Ethoxycarbonyl)furan-2-boronic acid, pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$47.00	$33.00
1g	98%	in stock	$155.00	$108.00
5g	98%	in stock	$462.00	$324.00
25g	98%	in stock	$1,878.00	$1,315.00

Description

• Catalog Number: AB73887
• Chemical Name: 5-(Ethoxycarbonyl)furan-2-boronic acid, pinacol ester
• CAS Number: 1073338-92-7
• Molecular Formula: C13H19BO5
• Molecular Weight: 266.098
• MDL Number: MFCD11855980
• SMILES: CCOC(=O)c1ccc(o1)B1OC(C(O1)(C)C)(C)C

Computed Properties

• Complexity: 339
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4

Upstream Synthesis Route

Ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan-2-carboxylate is a versatile compound widely utilized in chemical synthesis. This compound serves as a valuable building block for the preparation of various functionalized heterocycles and organic molecules. In organic synthesis, it is commonly employed as a key intermediate in the formation of complex structures due to its unique reactivity and functionality.One notable application of Ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan-2-carboxylate is in the Suzuki-Miyaura cross-coupling reaction, a powerful tool for constructing carbon-carbon bonds. By utilizing this compound as a boronic ester, it can undergo coupling with aryl or vinyl halides under palladium catalysis to form biaryl or bivinyl compounds. This reaction enables the synthesis of various biologically active compounds, pharmaceuticals, and organic materials with high efficiency and selectivity.Additionally, Ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan-2-carboxylate can participate in other important transformations such as nucleophilic substitution reactions, functional group interconversions, and heterocycle synthesis. Its unique structural features and reactivity make it a valuable component in the toolkit of synthetic chemists for the preparation of diverse molecular architectures with desired properties and functionalities.