1073339-21-5 | 2-Trifluoromethylphenylboronic acid, pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$34.00	$24.00
5g	98%	in stock	$111.00	$78.00
10g	98%	in stock	$212.00	$148.00
25g	98%	in stock	$465.00	$325.00

Description

• Catalog Number: AE15435
• Chemical Name: 2-Trifluoromethylphenylboronic acid, pinacol ester
• CAS Number: 1073339-21-5
• Molecular Formula: C13H16BF3O2
• Molecular Weight: 272.0711
• MDL Number: MFCD06795676
• SMILES: CC1(C)OB(OC1(C)C)c1ccccc1C(F)(F)F

Computed Properties

• Complexity: 325
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1

Upstream Synthesis Route

4,4,5,5-Tetramethyl-2-(2-(trifluoromethyl)phenyl)-1,3,2-dioxaborolane is a valuable reagent widely used in chemical synthesis. This compound is renowned for its versatile application in cross-coupling reactions, particularly in the field of organic synthesis. By serving as a boronic ester, it enables the formation of carbon-carbon bonds through palladium-catalyzed coupling reactions, such as Suzuki-Miyaura and Heck reactions. This efficient coupling process allows for the rapid synthesis of complex organic molecules with high precision and selectivity. Additionally, the unique steric and electronic properties of 4,4,5,5-Tetramethyl-2-(2-(trifluoromethyl)phenyl)-1,3,2-dioxaborolane make it a valuable building block for the construction of various functionalized organic compounds used in pharmaceuticals, agrochemicals, and materials science.