1088965-37-0 | Gsk-923295

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$18.00	$13.00
5mg	98%	in stock	$44.00	$31.00

Description

• Catalog Number: AD76976
• Chemical Name: Gsk-923295
• CAS Number: 1088965-37-0
• Molecular Formula: C32H38ClN5O4
• Molecular Weight: 592.1282
• MDL Number: MFCD16038931
• SMILES: CN(CC(=O)NC[C@@H](NC(=O)c1ccc(c(c1)Cl)OC(C)C)Cc1ccc(cc1)c1nc2n(c1)cccc2[C@@H](O)C)C

Computed Properties

• Complexity: 870
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 2
• Heavy Atom Count: 42
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 12
• XLogP3: 5

Literature

• Initial testing of the CENP-E inhibitor GSK923295A by the pediatric preclinical testing program.

  Pediatric blood & cancer 20120601

• First-time-in-human study of GSK923295, a novel antimitotic inhibitor of centromere-associated protein E (CENP-E), in patients with refractory cancer.

  Cancer chemotherapy and pharmacology 20120301