1089283-49-7 | GSK1904529A

Packsize	Purity	Availability	Price	Discounted Price
1mg	≥95%	in stock	$42.00	$29.00
5mg	≥95%	in stock	$150.00	$105.00
10mg	≥95%	in stock	$276.00	$193.00
25mg	≥95%	in stock	$587.00	$411.00
500mg	99% (HPLC)	in stock	$10,684.00	$7,479.00
1000mg	99% (HPLC)	in stock	$17,063.00	$11,944.00

Description

• Catalog Number: AE11232
• Chemical Name: GSK1904529A
• CAS Number: 1089283-49-7
• Molecular Formula: C44H47F2N9O5S
• Molecular Weight: 851.9631
• MDL Number: MFCD17010271
• SMILES: COc1cc(N2CCC(CC2)N2CCN(CC2)S(=O)(=O)C)c(cc1Nc1nccc(n1)c1c(nc2n1cccc2)c1ccc(c(c1)C(=O)Nc1c(F)cccc1F)OC)CC

Computed Properties

• Complexity: 1530
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 61
• Hydrogen Bond Acceptor Count: 14
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 12
• XLogP3: 6.8

Literature

• Identification of potent Yes1 kinase inhibitors using a library screening approach.

  Bioorganic & medicinal chemistry letters 20130801

• Antitumor activity of GSK1904529A, a small-molecule inhibitor of the insulin-like growth factor-I receptor tyrosine kinase.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090501

• Discovery and optimization of imidazo[1,2-a]pyridine inhibitors of insulin-like growth factor-1 receptor (IGF-1R).

  Bioorganic & medicinal chemistry letters 20090201