109-46-6 | 1,3-Dibutyl-2-thiourea

Packsize	Purity	Availability	Price	Discounted Price
25g	95%	in stock	$19.00	$13.00
100g	95%	in stock	$39.00	$27.00
500g	95%	in stock	$102.00	$71.00
1000g	95%	in stock	$181.00	$127.00

Description

• Catalog Number: AB57306
• Chemical Name: 1,3-Dibutyl-2-thiourea
• CAS Number: 109-46-6
• Molecular Formula: C9H20N2S
• Molecular Weight: 188.3335
• MDL Number: MFCD00004926
• SMILES: CCCCNC(=S)NCCCC

Computed Properties

• Complexity: 103
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 6
• XLogP3: 2.8

Upstream Synthesis Route

1,3-Dibutylthiourea is a versatile compound commonly used in chemical synthesis as a catalyst for various reactions. Its unique structure and properties make it particularly valuable in organic chemistry applications.One of the key applications of 1,3-Dibutylthiourea is in the synthesis of heterocyclic compounds. It can act as an effective catalyst in the formation of heterocycles through cyclization reactions. By facilitating the cyclization process, 1,3-Dibutylthiourea enables the efficient and selective synthesis of a wide range of heterocyclic structures.Additionally, 1,3-Dibutylthiourea is used in the synthesis of complex organic molecules by promoting key bond-forming reactions. Its ability to accelerate reactions and control the regioselectivity and stereoselectivity of the products makes it a valuable tool for synthetic chemists working on challenging molecular transformations.Overall, the application of 1,3-Dibutylthiourea in chemical synthesis extends to various areas of organic chemistry, where its catalytic properties play a crucial role in driving reactions towards desired products.

Literature

• Sensitization to thiourea derivatives among Finnish patients with suspected contact dermatitis.

  Contact dermatitis 20100701

• Simultaneous induction of non-canonical autophagy and apoptosis in cancer cells by ROS-dependent ERK and JNK activation.

  PloS one 20100101

• Positive patch-test reactions to mixed dialkyl thioureas: cross-sectional data from the North American Contact Dermatitis Group, 1994 to 2004.

  Dermatitis : contact, atopic, occupational, drug 20080101

• Allergic contact dermatitis from dibutylthiourea in a wet suit.

  Dermatitis : contact, atopic, occupational, drug 20040301

• HPLC analysis of alkyl thioureas in an orthopaedic brace and patch testing with pure ethylbutylthiourea.

  Contact dermatitis 20040101