1092485-88-5 | 3,5-Dichloro-4-fluorophenylboronic acid, pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
100mg	97%	in stock	$39.00	$27.00
250mg	97%	in stock	$60.00	$42.00
1g	97%	in stock	$93.00	$65.00
5g	97%	in stock	$462.00	$323.00

Description

• Catalog Number: AB58957
• Chemical Name: 3,5-Dichloro-4-fluorophenylboronic acid, pinacol ester
• CAS Number: 1092485-88-5
• Molecular Formula: C12H14BCl2FO2
• Molecular Weight: 290.9538
• MDL Number: MFCD15143599
• SMILES: CC1(C)OB(OC1(C)C)c1cc(Cl)c(c(c1)Cl)F

Computed Properties

• Complexity: 299
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1

Upstream Synthesis Route

2-(3,5-Dichloro-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a versatile chemical compound commonly employed in chemical synthesis processes. This unique boronic ester derivative serves as a valuable building block in the preparation of various organic compounds, owing to its reactivity and stability under diverse reaction conditions.One of the key applications of 2-(3,5-Dichloro-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is its utility in Suzuki-Miyaura cross-coupling reactions. This palladium-catalyzed coupling reaction allows for the efficient and selective formation of carbon-carbon bonds between an aryl or vinyl halide and an organoboron compound. By using this compound as a boron source, chemists can access a wide range of substituted biaryl and alkyl aryl products with high regioselectivity and functional group tolerance.Furthermore, the presence of both electron-withdrawing and electron-donating groups in the phenyl ring of 2-(3,5-Dichloro-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane imparts unique electronic properties to the compound. This property makes it a valuable tool in the synthesis of pharmaceutical intermediates, agrochemicals, and materials science applications where precise control over the electronic properties of the target molecules is crucial.Overall, the strategic incorporation of 2-(3,5-Dichloro-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane in chemical synthesis provides chemists with a powerful tool to access complex organic molecules with high efficiency and precision.