11021-14-0 | Ginsenoside rc

Packsize	Purity	Availability	Price	Discounted Price
1mg	98% by HPLC	in stock	$75.00	$52.00
5mg	≥98%	in stock	$88.00	$62.00
10mg	≥98%	in stock	$156.00	$109.00
25mg	≥98%	in stock	$345.00	$242.00

Description

• Catalog Number: AE08477
• Chemical Name: Ginsenoside rc
• CAS Number: 11021-14-0
• Molecular Formula: C53H90O22
• Molecular Weight: 1079.2685
• MDL Number: MFCD00133368
• SMILES: OC[C@H]1O[C@@H](O[C@H]2CC[C@]3([C@H](C2(C)C)CC[C@@]2([C@@H]3C[C@@H](O)[C@H]3[C@@]2(C)CC[C@@H]3[C@@](O[C@@H]2O[C@H](CO[C@@H]3O[C@H]([C@@H]([C@H]3O)O)CO)[C@H]([C@@H]([C@H]2O)O)O)(CCC=C(C)C)C)C)C)[C@@H]([C@H]([C@@H]1O)O)O[C@@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O

Computed Properties

• Complexity: 1950
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 29
• Heavy Atom Count: 75
• Hydrogen Bond Acceptor Count: 22
• Hydrogen Bond Donor Count: 14
• Rotatable Bond Count: 16
• XLogP3: 0.9

Literature

• Molecular mechanisms governing different pharmacokinetics of ginsenosides and potential for ginsenoside-perpetrated herb-drug interactions on OATP1B3.

  British journal of pharmacology 20150201

• Cloning and characterization of α-L-arabinofuranosidase and bifunctional α-L-arabinopyranosidase/β-D-galactopyranosidase from Bifidobacterium longum H-1.

  Journal of applied microbiology 20111101

• Microbial transformation of ginsenosides Rb1, Rb3 and Rc by Fusarium sacchari.

  Journal of applied microbiology 20100901

• HPLC-based activity profiling for GABA(A) receptor modulators: a new dihydroisocoumarin from Haloxylon scoparium.

  Journal of natural products 20100423

• Ginsenoside Rc, an active component of Panax ginseng, stimulates glucose uptake in C2C12 myotubes through an AMPK-dependent mechanism.

  Journal of ethnopharmacology 20100217

• Effects of extrusion process variables on extractable ginsenosides in wheat-ginseng extrudates.

  Journal of agricultural and food chemistry 20090325

• [A quantitative method using one marker for simultaneous assay of ginsenosides in Panax ginseng and P. notoginseng].

  Yao xue xue bao = Acta pharmaceutica Sinica 20081201

• Purification and characterization of new special ginsenosidase hydrolyzing multi-glycisides of protopanaxadiol ginsenosides, ginsenosidase type I.

  Chemical & pharmaceutical bulletin 20070201

• Transformation of ginsenosides Rb2 and Rc from Panax ginseng by food microorganisms.

  Biological & pharmaceutical bulletin 20051101

• Chromatographic resolution of glucosidic compounds, ginsenosides on polyethersulphone membrane, and its application to the quantitative immunoassay for ginseng saponins.

  Glycobiology 20051001

• [The effect of preparation method on the quality of shen-mai injection].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050501

• Embryotoxicity study of ginsenoside Rc and Re in in vitro rat whole embryo culture.

  Reproductive toxicology (Elmsford, N.Y.) 20041101

• Determination of ginsenosides Rb1, Rc, and Re in different dosage forms of ginseng by negative ion electrospray liquid chromatography-mass spectrometry.

  Journal of agricultural and food chemistry 20040811

• Structures of new dammarane-type Triterpene Saponins from the flower buds of Panax notoginseng and hepatoprotective effects of principal Ginseng Saponins.

  Journal of natural products 20030701

• Modulation of G protein alpha-subunit mRNA levels in discrete rat brain regions by cerebroventricular infusion of ginsenoside Rc and Rg1.

  Neurochemical research 20030501

• Ginsenoside Rc and Re stimulate c-fos expression in MCF-7 human breast carcinoma cells.

  Archives of pharmacal research 20030101

• Metabolism of ginsenoside R(c) by human intestinal bacteria and its related antiallergic activity.

  Biological & pharmaceutical bulletin 20020601

• Changes of [3H]MK-801, [3H]muscimol and [3H]flunitrazepam binding in rat brain by the prolonged ventricular infusion of ginsenoside Rc and Rg1.

  Pharmacological research 20010501

• Triterpene saponins from Vietnamese ginseng (Panax vietnamensis) and their hepatocytoprotective activity.

  Journal of natural products 20010401

• In vitro inhibitory effect of protopanaxadiol ginsenosides on tumor necrosis factor (TNF)-alpha production and its modulation by known TNF-alpha antagonists.

  Planta medica 20010401

• Effects of Ginsenoside Rb2 and Rc on inferior human sperm motility in vitro.

  The American journal of Chinese medicine 20010101