1110766-97-6 | (S,E)-3-(2,6-Dichloro-4-((4-(3-(1-(hexyloxy)ethyl)-2-methoxyphenyl)thiazol-2-yl)carbamoyl)phenyl)-2-methylacrylic acid

Packsize	Purity	Availability	Price	Discounted Price
1mg	97%	in stock	$16.00	$11.00
2mg	97%	in stock	$22.00	$16.00
10mg	97%	in stock	$58.00	$41.00

Description

• Catalog Number: AE19521
• Chemical Name: (S,E)-3-(2,6-Dichloro-4-((4-(3-(1-(hexyloxy)ethyl)-2-methoxyphenyl)thiazol-2-yl)carbamoyl)phenyl)-2-methylacrylic acid
• CAS Number: 1110766-97-6
• Molecular Formula: C29H32Cl2N2O5S
• Molecular Weight: 591.5458
• MDL Number: MFCD28502075
• SMILES: CCCCCCO[C@H](c1cccc(c1OC)c1csc(n1)NC(=O)c1cc(Cl)c(c(c1)Cl)/C=C(/C(=O)O)\C)C

Computed Properties

• Complexity: 822
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 39
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 13
• XLogP3: 7.7

Literature

• Development of a new knock-in mouse model and evaluation of pharmacological activities of lusutrombopag, a novel, nonpeptidyl small-molecule agonist of the human thrombopoietin receptor c-Mpl.

  Experimental hematology 20180301

• Efficacy of Repeated Lusutrombopag Administration for Thrombocytopenia in a Patient Scheduled for Invasive Hepatocellular Carcinoma Treatment.

  Internal medicine (Tokyo, Japan) 20171101

• Lusutrombopag increases hematocytes in a compensated liver cirrhosis patient.

  Clinical journal of gastroenterology 20170101

• [Avoidance of platelet transfusion with readministration of lusutrombopag before radiofrequency ablation in hepatocellular carcinoma:a case report].

  Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20170101

• Lusutrombopag: First Global Approval.

  Drugs 20160101