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S632A3, a new glutarimide antibiotic, suppresses lipopolysaccharide-induced pro-inflammatory responses via inhibiting the activation of glycogen synthase kinase 3β.
Experimental cell research 20121210
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Enantiomerization mechanism of thalidomide and the role of water and hydroxide ions.
Chemistry (Weinheim an der Bergstrasse, Germany) 20121105
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Synthesis and evaluation of a series of piperidine-2,6-dione-piperazine (piperidine) derivatives as multireceptor atypical antipsychotics.
Archiv der Pharmazie 20121101
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In vitro and in vivo activity of a palladacycle complex on Leishmania (Leishmania) amazonensis.
PLoS neglected tropical diseases 20120501
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Pharmacokinetics, metabolism and excretion of [(14)C]-lenalidomide following oral administration in healthy male subjects.
Cancer chemotherapy and pharmacology 20120301
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Synthesis and biological evaluation of molecular probes based on the 9-methylstreptimidone derivative DTCM-glutarimide.
Bioorganic & medicinal chemistry letters 20120101
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Borreria and Spermacoce species (Rubiaceae): A review of their ethnomedicinal properties, chemical constituents, and biological activities.
Pharmacognosy reviews 20120101
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Positive autoregulation of GDNF levels in the ventral tegmental area mediates long-lasting inhibition of excessive alcohol consumption.
Translational psychiatry 20111201
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Asparagine peptide lyases: a seventh catalytic type of proteolytic enzymes.
The Journal of biological chemistry 20111104
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Evaluation of apoptotic effect of cyclic imide derivatives on murine B16F10 melanoma cells.
Bioorganic & medicinal chemistry 20111101
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Inhibition of macrophage activation and suppression of graft rejection by DTCM-glutarimide, a novel piperidine derived from the antibiotic 9-methylstreptimidone.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20110901
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Synthesis of N-[(3S)-2,6-dioxo-1-(2-phenylethyl)-3-piperidinyl]-(2S)-2-methylbutanamide ((-)-julocrotine).
Journal of natural products 20110624
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Development of biomimetic catalytic oxidation methods and non-salt methods using transition metal-based acid and base ambiphilic catalysts.
Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110511
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One-electron reduction of N-chlorinated and N-brominated species is a source of radicals and bromine atom formation.
Chemical research in toxicology 20110321
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Chemical modification of L-glutamine to alpha-amino glutarimide on autoclaving facilitates Agrobacterium infection of host and non-host plants: A new use of a known compound.
BMC chemical biology 20110101
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Synthesis and antiviral activities of synthetic glutarimide derivatives.
Chemical & pharmaceutical bulletin 20101101
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Fractionation and identification of organic nitrogen species from bio-oil produced by fast pyrolysis of sewage sludge.
Bioresource technology 20101001
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Activity of the julocrotine, a glutarimide alkaloid from Croton pullei var. glabrior, on Leishmania (L.) amazonensis.
Parasitology research 20101001
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Multifaceted modes of action for the glutarimide-containing polyketides revealed.
Chembiochem : a European journal of chemical biology 20100924
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Synthesis of cyclic imides from simple diols.
Angewandte Chemie (International ed. in English) 20100823
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Mono- and bidentate imidates of five-coordinate nickel(II) with macrocyclic ligands: spectroscopic and photophysical properties.
Dalton transactions (Cambridge, England : 2003) 20100628
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Glutarimide alkaloids and a terpenoid benzoquinone from Cordia globifera.
Journal of natural products 20100528
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Transpiration response of 'slow-wilting' and commercial soybean (Glycine max (L.) Merr.) genotypes to three aquaporin inhibitors.
Journal of experimental botany 20100301
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Stereoselective aldol reaction of glutarimides using pseudo C(2) symmetry.
Organic letters 20100115
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Chemical-genetic profile analysis of five inhibitory compounds in yeast.
BMC chemical biology 20100101
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Cell-type specific analysis of translating RNAs in developing flowers reveals new levels of control.
Molecular systems biology 20100101
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Sustained spindle-assembly checkpoint response requires de novo transcription and translation of cyclin B1.
PloS one 20100101
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Transforming growth factor-β1 induces matrix metalloproteinase-9 and cell migration in astrocytes: roles of ROS-dependent ERK- and JNK-NF-κB pathways.
Journal of neuroinflammation 20100101
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Induction of cell cycle arrest at G1 and S phases and cAMP-dependent differentiation in C6 glioma by low concentration of cycloheximide.
BMC cancer 20100101
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Synthesis, structures and anti-HBV activities of derivatives of the glutarimide antibiotic cycloheximide.
The Journal of antibiotics 20091101
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iso-Migrastatin, migrastatin, and dorrigocin production in Streptomyces platensis NRRL 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase.
The Journal of biological chemistry 20091023
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Enantioselective approach to Securinega alkaloids. Total synthesis of securinine and (-)-norsecurinine.
The Journal of organic chemistry 20090821
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Second-generation highly potent and selective inhibitors of the hepatitis C virus NS3 serine protease.
Journal of medicinal chemistry 20090312
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Lactimidomycin, iso-migrastatin and related glutarimide-containing 12-membered macrolides are extremely potent inhibitors of cell migration.
Journal of the American Chemical Society 20090204
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3-(2,6-Dioxopiperidin-3-yl)-3-aza-bicyclo-[3.2.0]heptane-2,4-dione.
Acta crystallographica. Section E, Structure reports online 20090201
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Evaluation of new migrastatin and dorrigocin congeners unveils cell migration inhibitors with dramatically improved potency.
Bioorganic & medicinal chemistry letters 20081115
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A new series of dendrimers containing two ferrocenyl units and a Fréchet dendron around a triazine nucleus.
Organic letters 20081016
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Calorimetric and computational thermochemical study of 3,3-tetramethyleneglutaric acid, 3,3-tetramethyleneglutaric anhydride, and 3,3-tetramethyleneglutarimide.
The journal of physical chemistry. A 20081009
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Ultrasensitive hot-electron nanobolometers for terahertz astrophysics.
Nature nanotechnology 20080801
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Intercalation of cyclic imides in kaolinite.
Journal of colloid and interface science 20080715
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Solid-phase synthesis of tailed cyclic RGD peptides using glutamic acid: unexpected glutarimide formation.
Journal of peptide science : an official publication of the European Peptide Society 20080601
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Theoretical elucidation of the rhodium-catalyzed [4 + 2] annulation reactions.
Journal of computational chemistry 20080415
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Simple and facile synthesis of tetralone-spiro-glutarimides and spiro-bisglutarimides from Baylis-Hillman acetates.
Organic & biomolecular chemistry 20080321
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Chemical-genetic profile analysis in yeast suggests that a previously uncharacterized open reading frame, YBR261C, affects protein synthesis.
BMC genomics 20080101
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New lactimidomycin congeners shed insight into lactimidomycin biosynthesis in Streptomyces amphibiosporus.
Organic letters 20071206
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Cyclization of the acyl glucuronide metabolite of a neutral endopeptidase inhibitor to an electrophilic glutarimide: synthesis, reactivity, and mechanistic analysis.
Journal of medicinal chemistry 20071129
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The influence of modifications in imide fragment structure on 5-HT(1A) and 5-HT(7) receptor affinity and in vivo pharmacological properties of some new 1-(m-trifluoromethylphenyl)piperazines.
Bioorganic & medicinal chemistry 20071115
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Solubilization of single-walled carbon nanotubes by supramolecular complexes of barbituric acid and triaminopyrimidines.
Langmuir : the ACS journal of surfaces and colloids 20071023
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Investigation of N-hydroxythalidomide in vitro stability and comparison to other N-substituted derivatives.
Journal of pharmaceutical and biomedical analysis 20071018
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Exploring solvent versatility in immobilized cellulose-based chiral stationary phase for the enantioselective liquid chromatographic resolution of racemates.
Journal of separation science 20070501
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Cycloheximide resistance in the Lipomycetaceae revisited.
Canadian journal of microbiology 20070401
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The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention.
Molecular cancer 20070101
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A convenient allylsilane-N-acyliminium route toward indolizidine and quinolizidine alkaloids.
Beilstein journal of organic chemistry 20070101
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The unified equation for the evaluation of degenerated first-order reactions in dynamic electrophoresis.
Electrophoresis 20060801
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Efficient synthesis of fused bicyclic glutarimides. Its application to (+/-)-alloyohimbane and louisianin D.
Organic letters 20060706
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Chiral separations of piperidine-2,6-dione analogues on Chiralpak IA and Chiralpak IB columns by using HPLC.
Talanta 20060615
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Synthesis and anticonvulsant activities of N-Cbz-alpha-aminoglutarimidooxy carboxylate derivatives.
Archives of pharmacal research 20060601
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A versatile approach for the asymmetric syntheses of (1R,9aR)-epiquinamide and (1R,9aR)-homopumiliotoxin 223G.
Organic letters 20060330
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Synthesis and evaluation of 2,6-piperidinedione derivatives as potentially novel compounds with analgesic and other CNS activities.
Inflammopharmacology 20060301
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Synthesis of naturally derived bioactive compounds of agricultural interest.
Bioscience, biotechnology, and biochemistry 20060201
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Thalidomide attenuates nitric oxide mediated angiogenesis by blocking migration of endothelial cells.
BMC cell biology 20060101
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Isolation, structure determination and biological activity of a new glutarimide antibiotic, S632A3.
Journal of Asian natural products research 20060101
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Detailed studies on the enantioselective synthesis and HPLC enantioseparation of N-protected 3-hydroxyglutarimides.
Chirality 20051101
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EPR, UV-vis, magnetic, spectral studies and electrochemical behaviour of mononuclear transition metal complexes derived from novel hexa-aza-macrotricyclic ligand.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20051101
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Iso-migrastatin congeners from Streptomyces platensis and generation of a glutarimide polyketide library featuring the dorrigocin, lactimidomycin, migrastatin, and NK30424 scaffolds.
Journal of the American Chemical Society 20050831
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Identification of 3-(acylamino)azepan-2-ones as stable broad-spectrum chemokine inhibitors resistant to metabolism in vivo.
Journal of medicinal chemistry 20050210
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Three trifluoromethyl-substituted protoporphyrinogen IX oxidase inhibitors.
Acta crystallographica. Section C, Crystal structure communications 20050201
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Three new glutarimide alkaloids from Croton cuneatus.
Natural product research 20041001
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The migrastatin family: discovery of potent cell migration inhibitors by chemical synthesis.
Journal of the American Chemical Society 20040915
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Structure-dependent nonenzymatic deamidation of glutaminyl and asparaginyl pentapeptides.
The journal of peptide research : official journal of the American Peptide Society 20040501
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Synthesis of bridged azabicyclic structures via ring-closing olefin metathesis.
The Journal of organic chemistry 20031114
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An efficient approach to 3,4-disubstituted pyridin-2-ones. Formal synthesis of mappicine ketone.
The Journal of organic chemistry 20030711
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Asymmetric synthesis of (+)-L-733, 060 and (+)-CP-99, 994 based on a new chiral 3-piperidinol synthon.
Organic letters 20030529
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Chemical stabilities and biological activities of thalidomide and its N-alkyl analogs.
Pharmaceutical research 20020801
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5'-OH-thalidomide, a metabolite of thalidomide, inhibits angiogenesis.
Therapeutic drug monitoring 20020201
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Synthesis, spectroscopic characterization, stability assessment and DNA-binding of new 2,6-piperidinedione derivatives.
Farmaco (Societa chimica italiana : 1989) 20011001
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Synthesis and immunological activity of water-soluble thalidomide prodrugs.
Bioorganic & medicinal chemistry 20010501
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Structure-activity relationship of ligands of uracil phosphoribosyltransferase from Toxoplasma gondii.
Biochemical pharmacology 19940817
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Synthesis and anticonvulsant activity of 2-benzylglutarimides.
Journal of medicinal chemistry 19900301