1129541-09-8 | 1-Bromo-3-fluoro-5-(trifluoromethoxy)benzene

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$24.00	$17.00
250mg	95%	in stock	$29.00	$20.00
1g	95%	in stock	$71.00	$50.00
5g	95%	in stock	$336.00	$236.00

Description

• Catalog Number: AV17280
• Chemical Name: 1-Bromo-3-fluoro-5-(trifluoromethoxy)benzene
• CAS Number: 1129541-09-8
• Molecular Formula: C7H3BrF4O
• Molecular Weight: 258.9957
• MDL Number: MFCD22551456
• SMILES: Fc1cc(cc(c1)Br)OC(F)(F)F

Upstream Synthesis Route

1-Bromo-3-fluoro-5-(trifluoromethoxy)benzene, also known as $name$, plays a crucial role in chemical synthesis as a versatile building block. This compound is widely utilized in the pharmaceutical and agrochemical industries for the synthesis of various complex organic molecules. Its unique molecular structure consisting of a benzene ring substituted with bromine, fluorine, and trifluoromethoxy groups allows for a wide range of functionalization reactions.One of the key applications of 1-Bromo-3-fluoro-5-(trifluoromethoxy)benzene is in cross-coupling reactions, particularly in palladium-catalyzed C-C and C-X bond formations. This compound serves as an important coupling partner due to the presence of electron-withdrawing substituents, which enhance the reactivity and selectivity of the reaction. Furthermore, the trifluoromethoxy group can act as a directing group, facilitating regioselective functionalization of the benzene ring.In addition to cross-coupling reactions, 1-Bromo-3-fluoro-5-(trifluoromethoxy)benzene is also employed in the synthesis of biologically active molecules and functional materials. Its fluorinated and halogenated moieties are advantageous for drug discovery and development, as they can modulate the pharmacokinetic properties and biological activities of the target compounds. Moreover, the trifluoromethoxy group can impart desirable physicochemical properties, such as lipophilicity and metabolic stability, to the synthesized products.Overall, the strategic incorporation of 1-Bromo-3-fluoro-5-(trifluoromethoxy)benzene into chemical synthesis enables the efficient construction of diverse organic molecules with enhanced reactivity and functionality. Its versatile reactivity profile and structural motifs make it a valuable tool for the synthesis of complex molecules in various scientific disciplines.