113484-74-5 | Fmoc-gly-osu

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$9.00	$6.00
5g	97%	in stock	$26.00	$18.00
10g	97%	in stock	$42.00	$29.00
25g	97%	in stock	$83.00	$58.00
100g	97%	in stock	$330.00	$231.00

Description

• Catalog Number: AA11112
• Chemical Name: Fmoc-gly-osu
• CAS Number: 113484-74-5
• Molecular Formula: C21H18N2O6
• Molecular Weight: 394.3774
• MDL Number: MFCD00065651
• SMILES: O=C(NCC(=O)ON1C(=O)CCC1=O)OCC1c2ccccc2-c2c1cccc2

Upstream Synthesis Route

Fmoc-Gly-OSu is a key reagent widely used in peptide chemistry for the efficient synthesis of peptides with high purity and yield. This product plays a crucial role in solid-phase peptide synthesis (SPPS) due to its ability to selectively protect the amino group of glycine residues.In chemical synthesis, Fmoc-Gly-OSu is utilized as a derivative of glycine with a fluorenylmethyloxycarbonyl (Fmoc) protecting group and an N-hydroxysuccinimide (NHS) ester functionality. The Fmoc group provides temporary protection to the amino group of glycine, allowing for stepwise peptide elongation on solid-phase supports. The NHS ester moiety enhances the reactivity of the carboxylic acid group of the glycine residue, facilitating efficient coupling with the amino group of the incoming amino acid during peptide chain extension.By employing Fmoc-Gly-OSu in peptide synthesis, chemists can achieve precise control over the sequential assembly of amino acids, enabling the synthesis of complex peptides and peptide analogs. This versatile reagent offers excellent compatibility with a variety of coupling agents and solid supports, making it a valuable tool in the synthesis of bioactive peptides, pharmaceutical compounds, and peptide-based materials.