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A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model.
Journal of inherited metabolic disease 20160101
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N-methylnicotinamide is an endogenous probe for evaluation of drug-drug interactions involving multidrug and toxin extrusions (MATE1 and MATE2-K).
Clinical pharmacology and therapeutics 20121101
-
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Journal of medicinal chemistry 20120524
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Nitric oxide production and endothelium-dependent vasorelaxation ameliorated by N1-methylnicotinamide in human blood vessels.
Hypertension (Dallas, Tex. : 1979) 20120401
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In vitro and in silico strategies to identify OATP1B1 inhibitors and predict clinical drug-drug interactions.
Pharmaceutical research 20120201
-
Beneficial metabolic effects of 2',3',5'-tri-acetyl-N6- (3-hydroxylaniline) adenosine in the liver and plasma of hyperlipidemic hamsters.
PloS one 20120101
-
Nicotinamide, NAD(P)(H), and Methyl-Group Homeostasis Evolved and Became a Determinant of Ageing Diseases: Hypotheses and Lessons from Pellagra.
Current gerontology and geriatrics research 20120101
-
Characterization and crystallization of mouse aldehyde oxidase 3: from mouse liver to Escherichia coli heterologous protein expression.
Drug metabolism and disposition: the biological fate of chemicals 20111001
-
Two different hydrogen bond donor ligands together: a selectivity improvement in organometallic {Re(CO)3} anion hosts.
Inorganic chemistry 20110905
-
Characterization of organic anion-transporting polypeptide (Oatp) 1a1 and 1a4 null mice reveals altered transport function and urinary metabolomic profiles.
Toxicological sciences : an official journal of the Society of Toxicology 20110801
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Metabolomic assessment with CE-MS of the nutraceutical effect of Cystoseira spp extracts in an animal model.
Electrophoresis 20110801
-
Identification of urinary biomarkers from X-irradiated mice using NMR spectroscopy.
Radiation research 20110501
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Fluorescence Spectrometric Determination of Drugs Containing α-Methylene Sulfone/Sulfonamide Functional Groups Using N-Methylnicotinamide Chloride as a Fluorogenic Agent.
International journal of analytical chemistry 20110101
-
Nutritional and metabolic status of children with autism vs. neurotypical children, and the association with autism severity.
Nutrition & metabolism 20110101
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An insight into the metabolic responses of ultra-small superparamagnetic particles of iron oxide using metabonomic analysis of biofluids.
Nanotechnology 20101001
-
A novel pathway for nicotine degradation by Aspergillus oryzae 112822 isolated from tobacco leaves.
Research in microbiology 20100901
-
Urinary metabolic phenotyping differentiates children with autism from their unaffected siblings and age-matched controls.
Journal of proteome research 20100604
-
Protective effect of nicotinamide against poly(ADP-ribose) polymerase-1-mediated astrocyte death depends on its transporter-mediated uptake.
Life sciences 20100424
-
Diaqua-bis(5-bromo-2-hydroxy-benzoato)bis-(N-methyl-nicotinamide)zinc(II).
Acta crystallographica. Section E, Structure reports online 20100401
-
Development of a hydrophilic liquid interaction chromatography-high-performance liquid chromatography-tandem mass spectrometry based stable isotope dilution analysis and pharmacokinetic studies on bioactive pyridines in human plasma and urine after coffee consumption.
Analytical chemistry 20100215
-
Identification of hypoxanthine as a urine marker for non-Hodgkin lymphoma by low-mass-ion profiling.
BMC cancer 20100101
-
Effect of taurine supplementation on hyperhomocysteinemia and markers of oxidative stress in high fructose diet induced insulin resistance.
Diabetology & metabolic syndrome 20100101
-
A metabonomic comparison of urinary changes in Zucker and GK rats.
Journal of biomedicine & biotechnology 20100101
-
Nicotinamide and its metabolite N-methylnicotinamide increase skin vascular permeability in rats.
Clinical and experimental dermatology 20090401
-
Carrier-mediated uptake of 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium bromide (YM155 monobromide), a novel small-molecule survivin suppressant, into human solid tumor and lymphoma cells.
Drug metabolism and disposition: the biological fate of chemicals 20090301
-
Gastroduodenal mucosal defense.
Current gastroenterology reports 20081201
-
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Journal of medicinal chemistry 20081009
-
Development of oxidative stress by cytochrome P450 induction in rodents is selective for barbiturates and related to loss of pyridine nucleotide-dependent protective systems.
The Journal of biological chemistry 20080620
-
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Journal of medicinal chemistry 20080612
-
Dietary and genetic compromise in folate availability reduces acetylcholine, cognitive performance and increases aggression: critical role of S-adenosyl methionine.
The journal of nutrition, health & aging 20080401
-
N-methylnicotinamide failed to induce endothelial prostacyclin release in perfused rat hindquarters.
Pharmacological reports : PR 20080101
-
Effect of dronedarone on renal function in healthy subjects.
British journal of clinical pharmacology 20071201
-
1-Methylnicotinamide stimulates cell growth and inhibits hemoglobin synthesis in differentiating murine erythroleukemia cells.
Toxicology in vitro : an international journal published in association with BIBRA 20071201
-
Nitroso-imidacloprid irreversibly inhibits rabbit aldehyde oxidase.
Chemical research in toxicology 20071201
-
Functional characterization of testis-specific rodent multidrug and toxic compound extrusion 2, a class III MATE-type polyspecific H+/organic cation exporter.
American journal of physiology. Cell physiology 20071101
-
The comparative bioavailability of an extended-release niacin and lovastatin fixed dose combination tablet versus extended-release niacin tablet, lovastatin tablet and a combination of extended-release niacin tablet and lovastatin tablet.
Biopharmaceutics & drug disposition 20070901
-
N-methylnicotinamide inhibits arterial thrombosis in hypertensive rats.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20070901
-
Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation.
International journal of clinical pharmacology and therapeutics 20070801
-
Effect of the rate of niacin administration on the plasma and urine pharmacokinetics of niacin and its metabolites.
Journal of clinical pharmacology 20070601
-
Niacin nutritional status in HIV type 1-positive children: preliminary data.
Journal of pediatric gastroenterology and nutrition 20070501
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A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human.
Physiological genomics 20070424
-
Beyond lipids, pharmacological PPARalpha activation has important effects on amino acid metabolism as studied in the rat.
American journal of physiology. Endocrinology and metabolism 20070401
-
Metabonomics evaluations of age-related changes in the urinary compositions of male Sprague Dawley rats and effects of data normalization methods on statistical and quantitative analysis.
BMC bioinformatics 20070101
-
Changes in vitamin status of Indian Antarctic expeditioners during a one-month stay in Austral Summer.
Wilderness & environmental medicine 20070101
-
1H-NMR metabolic profiling of human neonatal urine.
Magma (New York, N.Y.) 20061201
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A metabonomics study of the hepatotoxicants galactosamine, methylene dianiline and clofibrate in rats.
Basic & clinical pharmacology & toxicology 20060901
-
Characteristics of thiamine uptake by the BeWo human trophoblast cell line.
Journal of biochemistry and molecular biology 20060731
-
Effect of standard nicotinamide in the prevention of type 1 diabetes in first degree relatives of persons with type 1 diabetes.
Autoimmunity 20060601
-
Tetraethylammonium and nicotine transport by the Malpighian tubules of insects.
Journal of insect physiology 20060501
-
Molecular tweezer and clip in aqueous solution: unexpected self-assembly, powerful host-guest complex formation, quantum chemical 1H NMR shift calculation.
Journal of the American Chemical Society 20060412
-
The regulation and inhibition of 17beta-hydroxysteroid dehydrogenase in breast cancer.
Molecular and cellular endocrinology 20060327
-
Evaluation of volatile ion-pair reagents for the liquid chromatography-mass spectrometry analysis of polar compounds and its application to the determination of methadone in human plasma.
Journal of pharmaceutical and biomedical analysis 20060224
-
Liquid chromatographic/mass spectrometric procedure for measurement of NAD catabolites in human and rat plasma and urine.
Nucleosides, nucleotides & nucleic acids 20060101
-
Electron transfer within complex II. Succinate:ubiquinone oxidoreductase of Escherichia coli.
The Journal of biological chemistry 20050930
-
Molecular and functional characterization of an Na+-independent choline transporter in rat astrocytes.
Journal of neurochemistry 20050901
-
Increased tubular organic ion clearance following chronic ACE inhibition in patients with type 1 diabetes.
Kidney international 20050601
-
Tryptophan-NAD+ pathway metabolites as putative biomarkers and predictors of peroxisome proliferation.
Archives of toxicology 20050401
-
Parkinson's disease: the first common neurological disease due to auto-intoxication?
QJM : monthly journal of the Association of Physicians 20050301
-
Identification of aldehyde oxidase as the neonicotinoid nitroreductase.
Chemical research in toxicology 20050201
-
Nicotinamide homeostasis: a xenobiotic pathway that is key to development and degenerative diseases.
Medical hypotheses 20050101
-
[Pellagra].
Sante (Montrouge, France) 20050101
-
The effect of a series of organic cations upon the plasmalemmal serotonin transporter, SERT.
Life sciences 20041119
-
The role of advanced glycation in reduced organic cation transport associated with experimental diabetes.
The Journal of pharmacology and experimental therapeutics 20041101
-
Niacin metabolite excretion in alcoholic pellagra and AIDS patients with and without diarrhea.
Nutrition (Burbank, Los Angeles County, Calif.) 20040901
-
Effects of feeding and body weight loss on the 1H-NMR-based urine metabolic profiles of male Wistar Han rats: implications for biomarker discovery.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20040101
-
Development of a multivariate statistical model to predict peroxisome proliferation in the rat, based on urinary 1H-NMR spectral patterns.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20040101
-
Molecular tweezers and clips as synthetic receptors. Molecular recognition and dynamics in receptor-substrate complexes.
Accounts of chemical research 20031201
-
Reduced tubular cation transport in diabetes: prevented by ACE inhibition.
Kidney international 20030601
-
Influence of molecular structure on substrate binding to the human organic cation transporter, hOCT1.
Molecular pharmacology 20030301
-
Evidence for a carrier-mediated mechanism for thiamine transport to human jejunal basolateral membrane vesicles.
Digestive diseases and sciences 20030101
-
[Connection between changing the vitamin and immune status and the character of the throat microflora in patients with chronic tonsillitis].
Otolaryngologia polska = The Polish otolaryngology 20030101
-
Potential urinary and plasma biomarkers of peroxisome proliferation in the rat: identification of N-methylnicotinamide and N-methyl-4-pyridone-3-carboxamide by 1H nuclear magnetic resonance and high performance liquid chromatography.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20030101
-
Cellular and molecular aspects of thiamin uptake by human liver cells: studies with cultured HepG2 cells.
Biochimica et biophysica acta 20021223
-
Functional characterization of mouse cation transporter mOCT2 compared with mOCT1.
Biochemical and biophysical research communications 20020823
-
Intramolecular electron transfer in cytochrome cd(1) nitrite reductase from Pseudomonas stutzeri; kinetics and thermodynamics.
Biophysical chemistry 20020710
-
cDNA cloning, functional characterization, and tissue distribution of an alternatively spliced variant of organic cation transporter hOCT2 predominantly expressed in the human kidney.
Journal of the American Society of Nephrology : JASN 20020701
-
Copper complexes with bioactive ligands. Part II--Antifungal activity.
Folia microbiologica 20020101
-
Self-assembly of polymer and sheet structures from palladium(II) complexes by hydrogen bonding between carboxamide substituents.
Inorganic chemistry 20011119
-
Ventricular choline transport: a role for organic cation transporter 2 expressed in choroid plexus.
The Journal of biological chemistry 20011109
-
Mechanism of thiamine uptake by human jejunal brush-border membrane vesicles.
American journal of physiology. Cell physiology 20010901
-
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.
American journal of physiology. Renal physiology 20010901
-
Intramolecular electron transfer from c heme to d1 heme in bacterial cytochrome cd1 nitrite reductase occurs over the same distances at very different rates depending on the source of the enzyme.
Biochemistry 20010724
-
Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats.
Bioscience, biotechnology, and biochemistry 20010601
-
The metabolism of nicotinamide in human liver cirrhosis: a study on N-methylnicotinamide and 2-pyridone-5-carboxamide production.
The American journal of gastroenterology 20010401
-
Cytosolic xanthine oxidoreductase mediated bioactivation of ethanol to acetaldehyde and free radicals in rat breast tissue. Its potential role in alcohol-promoted mammary cancer.
Toxicology 20010307
-
Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2.
Molecular pharmacology 20010201
-
Hepatic uptake of synthetic chlorogenic acid derivatives by the organic anion transport proteins.
The Journal of pharmacology and experimental therapeutics 20010101
-
Transport of [3H]MPP+ in an immortalized rat brain microvessel endothelial cell line (RBE 4).
Naunyn-Schmiedeberg's archives of pharmacology 20010101
-
Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects.
Teratogenesis, carcinogenesis, and mutagenesis 20010101
-
Copper complexes with bioactive ligands Part I--Antimicrobial activity.
Folia microbiologica 20010101
-
Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa).
The Journal of pharmacology and experimental therapeutics 19980701
-
Cloning and characterization of two human polyspecific organic cation transporters.
DNA and cell biology 19970701
-
Gentamicin nephrotoxicity. I. Degree and permanence of acquired insensitivity.
The Journal of laboratory and clinical medicine 19821001
