114-76-1 | Sodium phenylpyruvate monohydrate

Packsize	Purity	Availability	Price	Discounted Price
1g	80%	in stock	$16.00	$11.00
5g	80%	in stock	$36.00	$25.00
10g	80%	in stock	$58.00	$40.00
25g	80%	in stock	$129.00	$90.00

Description

• Catalog Number: AA13125
• Chemical Name: Sodium phenylpyruvate monohydrate
• CAS Number: 114-76-1
• Molecular Formula: C9H7NaO3
• Molecular Weight: 186.1398
• MDL Number: MFCD00149109
• SMILES: O=C(C(=O)[O-])Cc1ccccc1.[Na+]

Computed Properties

• Complexity: 185
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3

Literature

• Phenylpyruvic acid decreases glucose-6-phosphate dehydrogenase activity in rat brain.

  Cellular and molecular neurobiology 20121001

• Characterization of D-lactate dehydrogenase from Pediococcus acidilactici that converts phenylpyruvic acid into phenyllactic acid.

  Biotechnology letters 20120501

• Resolving phenylalanine metabolism sheds light on natural synthesis of penicillin G in Penicillium chrysogenum.

  Eukaryotic cell 20120201

• Characterization of D-lactate dehydrogenase producing D-3-phenyllactic acid from Pediococcus pentosaceus.

  Bioscience, biotechnology, and biochemistry 20120101

• Novel fungal phenylpyruvate reductase belongs to d-isomer-specific 2-hydroxyacid dehydrogenase family.

  Biochimica et biophysica acta 20111201

• Exploring the catalytic potential of the 3-His mononuclear nonheme Fe(II) center: discovery and characterization of an unprecedented maltol cleavage activity.

  Journal of inorganic biochemistry 20110901

• Identification of genes in the phenylalanine metabolic pathway by ectopic expression of a MYB transcription factor in tomato fruit.

  The Plant cell 20110701

• Novel potential markers of nasopharyngeal carcinoma for diagnosis and therapy.

  Clinical biochemistry 20110601

• Study on urinary metabolic profile of phenylketonuria by micellar electrokinetic capillary chromatography with dual electrochemical detection--potential clinical application in fast diagnosis of phenylketonuria.

  Analytica chimica acta 20110523

• Efficient conversion of phenylpyruvic acid to phenyllactic acid by using whole cells of Bacillus coagulans SDM.

  PloS one 20110101

• Bioconversion of phenylpyruvate to phenyllactate: gene cloning, expression, and enzymatic characterization of D- and L1-lactate dehydrogenases from Lactobacillus plantarum SK002.

  Applied biochemistry and biotechnology 20100901

• Kinetic-based high-throughput screening assay to discover novel classes of macrophage migration inhibitory factor inhibitors.

  Journal of biomolecular screening 20100401

• Tissue-specific activation of mitogen-activated protein kinases for expression of transthyretin by phenylalanine and its metabolite, phenylpyruvic acid.

  Experimental & molecular medicine 20100227

• 3-Phenyllactic acid production by substrate feeding and pH-control in fed-batch fermentation of Lactobacillus sp. SK007.

  Bioresource technology 20091101

• Purification and partial characterization of Lactobacillus species SK007 lactate dehydrogenase (LDH) catalyzing phenylpyruvic acid (PPA) conversion into phenyllactic acid (PLA).

  Journal of agricultural and food chemistry 20080409

• Mechanism of benzaldehyde lyase studied via thiamin diphosphate-bound intermediates and kinetic isotope effects.

  Biochemistry 20080325

• Crystal structure of VioE, a key player in the construction of the molecular skeleton of violacein.

  The Journal of biological chemistry 20080307

• Organic acid concentrations in amniotic fluid found in normal and Down syndrome pregnancies.

  Fetal diagnosis and therapy 20080201

• Near-ultraviolet photolysis of beta-phenylpyruvic acid generates free radicals and results in DNA damage.

  Journal of photochemistry and photobiology. B, Biology 20071214

• Phenylpyruvate tautomerase activity of trans-3-chloroacrylic acid dehalogenase: evidence for an enol intermediate in the dehalogenase reaction?

  Biochemistry 20070821

• Nucleophile selectivity of chorismate-utilizing enzymes.

  Chembiochem : a European journal of chemical biology 20070416

• Biotransformation of phenylpyruvic acid to phenyllactic acid by growing and resting cells of a Lactobacillus sp.

  Biotechnology letters 20070401

• Characterization and application of D-amino acid oxidase and catalase within permeabilized Pichia pastoris cells in bioconversions.

  Applied biochemistry and biotechnology 20070301

• Iron-catalyzed C2-C3 bond cleavage of phenylpyruvate with O2: insight into aliphatic C-C bond-cleaving dioxygenases.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

• Chemical conversion of alpha-amino acids into alpha-keto acids by 4,5-epoxy-2-decenal.

  Journal of agricultural and food chemistry 20060809

• Engineered phenylalanine dehydrogenase in organic solvents: homogeneous and biphasic enzymatic reactions.

  Organic & biomolecular chemistry 20051221

• Plant-derived anti-inflammatory compounds affect MIF tautomerase activity.

  International immunopharmacology 20050501

• A molecularly imprinted polymer-based synthetic transaminase.

  Journal of the American Chemical Society 20040714

• Estrogen-inducible uterine flavonoid binding sites: is it time to reconsider?

  The Journal of steroid biochemistry and molecular biology 20040401

• Beta-phenylpyruvate and glucose uptake in isolated mouse soleus muscle and cultured C2C12 muscle cells.

  Journal of cellular biochemistry 20031201

• Glutamine:phenylpyruvate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus HB8.

  Journal of biochemistry 20031201

• Effects of phenylalanine and phenylpyruvate on ATP-ADP hydrolysis by rat blood serum.

  Amino acids 20030601

• Characterization of the inhibition of pyruvate kinase caused by phenylalanine and phenylpyruvate in rat brain cortex.

  Brain research 20030411

• Glucose-lowering effect of beta-phenylpyruvate in neonatal mice: a possible mechanism for phenylketonuria-related neurodegenerative changes.

  Brain research. Developmental brain research 20030314

• Asbjørn Følling and the discovery of phenylketonuria.

  Journal of the history of the neurosciences 20030301

• (4-Hydroxyphenyl)pyruvate dioxygenase from Streptomyces avermitilis: the basis for ordered substrate addition.

  Biochemistry 20030225

• [Characterization of phenylpyruvic acid and beta-benzyl phenylpyruvic acid by UV, IR, MS, and 1H NMR].

  Guang pu xue yu guang pu fen xi = Guang pu 20030201

• p-Sulfooxyphenylpyruvic acid from the red macro alga Ceratodictyon spongiosum and its sponge symbiont Haliclona cymaeformis.

  Phytochemistry 20020601

• Aromatic amino acid biosynthesis and production of related compounds from p-hydroxyphenylpyruvic acid by rumen bacteria, protozoa and their mixture.

  Amino acids 20020101

• Phenylalanine and phenylpyruvate inhibit ATP diphosphohydrolase from rat brain cortex.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20011101