114446-57-0 | (1R)-2-Chloro-1-(2,4-dichlorophenyl)ethanol

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$35.00	$24.00
5g	98%	in stock	$96.00	$67.00
25g	98%	in stock	$333.00	$233.00

Description

• Catalog Number: AA18472
• Chemical Name: (1R)-2-Chloro-1-(2,4-dichlorophenyl)ethanol
• CAS Number: 114446-57-0
• Molecular Formula: C8H7Cl3O
• Molecular Weight: 225.4996
• MDL Number: MFCD09863567
• SMILES: ClC[C@@H](c1ccc(cc1Cl)Cl)O

Computed Properties

• Complexity: 142
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 2.9

Upstream Synthesis Route

In chemical synthesis, (R)-alpha-(Chloromethyl)-2,4-dichlorobenzyl alcohol serves as a versatile building block that enables the creation of a wide range of compounds with diverse functionalities. This compound is commonly used as a key intermediate in the preparation of various pharmaceuticals, agrochemicals, and advanced materials. Its unique structure and reactivity make it a valuable tool for introducing specific functional groups into organic molecules, allowing chemists to design and fabricate complex structures with precision. Additionally, the (R)-configuration of the compound imparts stereochemical control during synthesis, which is crucial for accessing enantiomerically pure products in asymmetric transformations and chiral synthesis processes.

Literature

• Asymmetric chemoenzymatic synthesis of miconazole and econazole enantiomers. The importance of chirality in their biological evaluation.

  The Journal of organic chemistry 20110401