1150114-56-9 | 2-(Benzyloxy)-3,5-difluorophenylboronic acid

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$62.00	$44.00
250mg	98%	in stock	$90.00	$63.00
1g	98%	in stock	$297.00	$208.00
5g	98%	in stock	$851.00	$596.00

Description

• Catalog Number: AA20053
• Chemical Name: 2-(Benzyloxy)-3,5-difluorophenylboronic acid
• CAS Number: 1150114-56-9
• Molecular Formula: C13H11BF2O3
• Molecular Weight: 264.0324
• MDL Number: MFCD11855849
• SMILES: Fc1cc(F)c(c(c1)B(O)O)OCc1ccccc1

Upstream Synthesis Route

The (2-(Benzyloxy)-3,5-difluorophenyl)boronic acid is a versatile organoboron compound that finds significant application in chemical synthesis. This compound is commonly used as a key building block in the formation of various complex molecules, particularly in the field of medicinal chemistry and material science.The boronic acid functionality in this compound allows for versatile reactivity with various nucleophiles, such as Grignard reagents and organolithium compounds. The benzyloxy group provides stability to the boronic acid under a range of reaction conditions, making it a valuable precursor in cross-coupling reactions.One of the prominent applications of (2-(Benzyloxy)-3,5-difluorophenyl)boronic acid is in Suzuki-Miyaura cross-coupling reactions. In this reaction, the boronic acid reacts with an aryl or vinyl halide in the presence of a palladium catalyst to form a new carbon-carbon bond. This powerful synthetic tool enables the efficient synthesis of biaryl and polyaryl compounds, which are prevalent in pharmaceuticals, agrochemicals, and materials science.Overall, the (2-(Benzyloxy)-3,5-difluorophenyl)boronic acid serves as a valuable building block in organic synthesis, offering chemists a versatile and reliable tool for accessing diverse chemical structures with potential applications in drug discovery, materials development, and other areas of chemical research.