1152441-29-6 | 5-Amino-2-fluorophenylboronic acid pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$32.00	$22.00
250mg	95%	in stock	$33.00	$24.00
1g	95%	in stock	$113.00	$80.00
5g	95%	in stock	$328.00	$230.00
10g	95%	in stock	$573.00	$402.00
25g	95%	in stock	$1,226.00	$858.00

Description

• Catalog Number: AA21158
• Chemical Name: 5-Amino-2-fluorophenylboronic acid pinacol ester
• CAS Number: 1152441-29-6
• Molecular Formula: C12H17BFNO2
• Molecular Weight: 237.0783
• MDL Number: MFCD16996293
• SMILES: CC1(C)OB(OC1(C)C)c1cc(N)ccc1F

Computed Properties

• Complexity: 282
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1

Upstream Synthesis Route

4-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline, a versatile chemical compound, plays a crucial role in modern chemical synthesis processes. Its unique structure and properties make it an invaluable tool in various organic transformations.This compound is commonly utilized as a key building block in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. Its incorporation into target molecules can lead to improved biological activity, enhanced stability, and selective reactivity.In organic synthesis, 4-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline serves as a valuable reagent for cross-coupling reactions, specifically in palladium-catalyzed coupling reactions. Its boron-containing moiety facilitates rapid and efficient C-C bond formation, making it a crucial tool for the construction of complex molecular frameworks.Furthermore, this compound can be employed in the functionalization of aromatic systems, enabling the introduction of fluorine atoms at specific positions. This fluorinated derivative can exhibit unique properties such as altered lipophilicity, enhanced biological activity, and improved metabolic stability, making it a valuable tool in drug discovery and materials science.Overall, the application of 4-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline in chemical synthesis highlights its significance as a versatile and indispensable reagent for the creation of novel molecules with tailored properties and functionalities.