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AA20636

1155-00-6 | Bis(2-nitrophenyl) disulfide

Packsize Purity Availability Price Discounted Price    Quantity
250mg 97% in stock $15.00 $10.00 -   +
1g 97% in stock $16.00 $11.00 -   +
5g 97% in stock $23.00 $16.00 -   +
25g 97% in stock $39.00 $27.00 -   +
100g 97% in stock $145.00 $101.00 -   +
500g 97% in stock $512.00 $358.00 -   +

*All products are for research use only and not intended for human or animal use.

*All prices are in USD.

Description
Catalog Number: AA20636
Chemical Name: Bis(2-nitrophenyl) disulfide
CAS Number: 1155-00-6
Molecular Formula: C12H8N2O4S2
Molecular Weight: 308.3329
MDL Number: MFCD00007130
SMILES: [O-][N+](=O)c1ccccc1SSc1ccccc1[N+](=O)[O-]

 

Upstream Synthesis Route
  • Bis(2-nitrophenyl) disulfide, also known as BNDS, is a versatile compound widely used in chemical synthesis as a cross-linking agent and as a reagent for thiol-disulfide exchange reactions. In organic chemistry, BNDS plays a crucial role in the formation of disulfide bonds between sulfhydryl groups, aiding in the synthesis of various organic compounds and polymers.One common application of BNDS is in peptide synthesis, where it is utilized for the selective protection of cysteine residues to prevent unwanted chemical reactions during peptide assembly. BNDS can be used to temporarily block thiol groups in peptides, allowing for specific modifications to be made before deprotection to yield the final peptide product.Additionally, BNDS is employed in the synthesis of disulfide-containing drugs and pharmaceuticals, where controlled disulfide bond formation is essential for the stability and bioactivity of the final product. By acting as a bridge between sulfhydryl groups, BNDS facilitates the formation of structurally complex molecules with enhanced pharmacological properties.Furthermore, BNDS finds application in materials science for the preparation of disulfide-linked polymers and dendrimers, where controlled cross-linking is crucial for the mechanical strength and thermal stability of the resulting materials. The unique reactivity of BNDS towards thiols makes it a valuable tool in designing novel polymeric architectures with tailored properties for various industrial applications.In conclusion, Bis(2-nitrophenyl) disulfide is a versatile compound with diverse applications in chemical synthesis, particularly in the formation of disulfide bonds for peptide modification, drug synthesis, and polymer engineering. Its selective reactivity towards sulfhydryl groups makes it an indispensable reagent for designing complex molecules and materials with tailored functionalities and properties.
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