-
Hopeahainol A binds reversibly at the acetylcholinesterase (AChE) peripheral site and inhibits enzyme activity with a novel higher order concentration dependence.
Chemico-biological interactions 20161125
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Targeted oxidation of Torpedo californica acetylcholinesterase by singlet oxygen: identification of N-formylkynurenine tryptophan derivatives within the active-site gorge of its complex with the photosensitizer methylene blue.
The Biochemical journal 20121115
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Congenital myasthenic syndromes: current diagnostic and therapeutic approaches.
Neuropediatrics 20120801
-
Myasthenia gravis can cause camptocormia.
Journal of neurology, neurosurgery, and psychiatry 20120401
-
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
PLoS computational biology 20111201
-
Discordant thymectomy in identical twins concordant for myasthenia gravis.
Annals of internal medicine 20111004
-
Multiple inhibitory actions of lidocaine on Torpedo nicotinic acetylcholine receptors transplanted to Xenopus oocytes.
Journal of neurochemistry 20110601
-
Preparation, in vitro screening and molecular modelling of symmetrical bis-quinolinium cholinesterase inhibitors--implications for early myasthenia gravis treatment.
Bioorganic & medicinal chemistry letters 20110415
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Preparation and in vitro screening of symmetrical bis-isoquinolinium cholinesterase inhibitors bearing various connecting linkage--implications for early Myasthenia gravis treatment.
European journal of medicinal chemistry 20110201
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Failure to reverse prolonged vecuronium-induced neuromuscular blockade with edrophonium in an anesthetized dog.
Journal of the American Animal Hospital Association 20110101
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A predictive ligand-based Bayesian model for human drug-induced liver injury.
Drug metabolism and disposition: the biological fate of chemicals 20101201
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Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Bioorganic & medicinal chemistry letters 20101101
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Design, synthesis, and biological evaluation of coumarin derivatives tethered to an edrophonium-like fragment as highly potent and selective dual binding site acetylcholinesterase inhibitors.
ChemMedChem 20100903
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Rapid and label-free screening of enzyme inhibitors using segmented flow electrospray ionization mass spectrometry.
Journal of the American Society for Mass Spectrometry 20100701
-
Rapid chemical antagonism of neuromuscular blockade by L-cysteine adduction to and inactivation of the olefinic (double-bonded) isoquinolinium diester compounds gantacurium (AV430A), CW 002, and CW 011.
Anesthesiology 20100701
-
Myasthenia gravis in an adolescent patient presenting to the pediatric emergency department.
Pediatric emergency care 20100501
-
[Neuromuscular disease--myasthenia gravis].
MMW Fortschritte der Medizin 20100114
-
Pseudo-internuclear ophthalmoplegia as a sign of overlapping myasthenia gravis in a patient with 'intractable' hypothyroidism.
Internal medicine (Tokyo, Japan) 20100101
-
A case of diplopia and arm weakness.
BMJ (Clinical research ed.) 20091125
-
Dysfunction of the longitudinal muscles of the oesophagus in eosinophilic oesophagitis.
Gut 20090801
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Racial differences in myasthenia gravis in Alabama.
Muscle & nerve 20090301
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Clinical implications of new neuromuscular concepts and agents: so long, neostigmine! So long, sux!
Journal of critical care 20090301
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Generalized and neurotransmitter-selective noradrenergic denervation in Parkinson's disease with orthostatic hypotension.
Movement disorders : official journal of the Movement Disorder Society 20080915
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Reversal of asynchrony between circular and longitudinal muscle contraction in nutcracker esophagus by atropine.
Gastroenterology 20080901
-
Evaluation and diagnosis of noncardiac chest pain.
Disease-a-month : DM 20080901
-
Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors.
Bioorganic & medicinal chemistry 20080801
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[Surprising etiology of chronic deglutition disorder. Diagnosis at a glance in dysphagia].
MMW Fortschritte der Medizin 20080605
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Cardiovascular and autonomic nervous effects of edrophonium and atropine combinations during neuromuscular blockade antagonism in sheep.
Veterinary anaesthesia and analgesia 20080501
-
Electrophysiological signs and the prevalence of adverse effects of acetylcholinesterase inhibitors in patients with myasthenia gravis.
Muscle & nerve 20080301
-
Cholinergic stimulation induces asynchrony between the circular and longitudinal muscle contraction during esophageal peristalsis.
American journal of physiology. Gastrointestinal and liver physiology 20080301
-
Fiberoptic endoscopic evaluation of swallowing with simultaneous Tensilon application in diagnosis and therapy of myasthenia gravis.
Journal of neurology 20080201
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Myasthenia gravis-like syndrome in a Hereford heifer.
Journal of veterinary internal medicine 20080101
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Relevance of mild ineffective oesophageal motility (IOM) and potential pharmacological reversibility of severe IOM in patients with gastro-oesophageal reflux disease.
Alimentary pharmacology & therapeutics 20071115
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[Videofluorographic evaluation of dysphagia in a patient with myasthenia gravis].
Rinsho shinkeigaku = Clinical neurology 20071001
-
A case report of myasthenia gravis localized to the larynx.
Auris, nasus, larynx 20070901
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Diverse inhibitory actions of quaternary ammonium cholinesterase inhibitors on Torpedo nicotinic ACh receptors transplanted to Xenopus oocytes.
British journal of pharmacology 20070801
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Sugammadex reversal of rocuronium-induced neuromuscular blockade: a comparison with neostigmine-glycopyrrolate and edrophonium-atropine.
Anesthesia and analgesia 20070301
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Is there still a role for edrophonium in diagnosing ocular myasthenia.
European journal of neurology 20070301
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[Thoracic pain caused by esophageal dysfunction in patients with ischemic cardiopathy].
Medicina clinica 20070120
-
Dropped head sign as the only symptom of myasthenia gravis.
Internal medicine (Tokyo, Japan) 20070101
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Pseudomyasthenia in a patient with pontine glioma.
Clinical neurology and neurosurgery 20061201
-
LC/MS/MS analysis of quaternary ammonium drugs and herbicides in whole blood.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061002
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Edrophonium provocative testing for the evaluation of upper gastrointestinal hypersensitivity in patients with nonulcer dyspepsia.
Digestive diseases and sciences 20060801
-
A systematic review of diagnostic studies in myasthenia gravis.
Neuromuscular disorders : NMD 20060701
-
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
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Automated method, based on micro-sequential injection, for the study of enzyme kinetics and inhibition.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20060101
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Is pancreatic polypeptide response to food ingestion a reliable index of vagal function in type 1 diabetes?
Scandinavian journal of clinical and laboratory investigation 20060101
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Is NMDA receptor activation essential for the production of locomotor-like activity in the neonatal rat spinal cord?
Journal of neurophysiology 20051201
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Bread-and-butter in diagnosis of myasthenia gravis.
Archives of neurology 20051201
-
Nonresponsiveness to anticholinesterase agents in patients with MuSK-antibody-positive MG.
Neurology 20051108
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Advances in the diagnosis of neuromuscular junction disorders.
American journal of physical medicine & rehabilitation 20050801
-
Clinical utility of videofluorography with concomitant Tensilon administration in the diagnosis of bulbar myasthenia gravis.
Digestive diseases and sciences 20050501
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Edrophonium-induced right ventricular outflow tract tachycardia.
Pacing and clinical electrophysiology : PACE 20050101
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[Role of esophageal provocative tests in the investigation of patients with chest pain of undetermined origin].
Arquivos de gastroenterologia 20050101
-
Congenital myasthenia gravis in Smooth-Haired Miniature Dachshund dogs.
Journal of veterinary internal medicine 20050101
-
Sensory testing of the esophagus.
Journal of clinical gastroenterology 20040901
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'Dropped head sign' in myasthenia gravis.
Neuromuscular disorders : NMD 20040901
-
Does acetylcholinesterase inhibition affect catecholamine secretion by adrenomedullary cells?
The Israel Medical Association journal : IMAJ 20040701
-
Nitric oxide and cardiac muscarinic control in humans.
Hypertension (Dallas, Tex. : 1979) 20040501
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Mutation in the AChR ion channel gate underlies a fast channel congenital myasthenic syndrome.
Neurology 20040413
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Response of thymectomy: clinical and pathological characteristics among seronegative and seropositive myasthenia gravis patients.
Acta neurologica Scandinavica 20040301
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Myasthenia gravis in childhood.
Binocular vision & strabismus quarterly 20040101
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Prevalence of esophageal disorders in patients with recurrent chest pain.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20040101
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[Biochemical characteristics of cholinesterase from taenia Hymenolepis diminuta].
Wiadomosci parazytologiczne 20040101
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Natural monomeric form of fetal bovine serum acetylcholinesterase lacks the C-terminal tetramerization domain.
Biochemistry 20031230
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Edrophonium effectively antagonizes neuromuscular block at the laryngeal adductors induced by rapacuronium, rocuronium and cisatracurium, but not mivacurium.
Canadian journal of anaesthesia = Journal canadien d'anesthesie 20031101
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Interactions of edrophonium with neostigmine in the rat trachea.
Anesthesia and analgesia 20031001
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Cage amines as the stopper inhibitors of cholinesterases.
Bioorganic & medicinal chemistry letters 20030901
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Positive tensilon test and intracranial tumor: a case report.
European journal of ophthalmology 20030701
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Facile synthesis of [11C]edrophonium and its analogues as new potential PET imaging agents for heart acetylcholinesterase.
Bioorganic & medicinal chemistry letters 20030519
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The edrophonium test.
Seminars in neurology 20030301
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Development of generalized disease at 2 years in patients with ocular myasthenia gravis.
Archives of neurology 20030201
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Simplified tilt table test protocol with continuous upright position during medication administration and no hydration.
Pacing and clinical electrophysiology : PACE 20030101
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[Premonitory depression].
Ryoikibetsu shokogun shirizu 20030101
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Potencies and selectivities of inhibitors of acetylcholinesterase and its molecular forms in normal and Alzheimer's disease brain.
Acta biologica Hungarica 20030101
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Autosomal recessive limb girdle myasthenia in two sisters.
Neurology India 20021201
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A comparison of the chronotropic and dromotropic actions between adenosine triphosphate and edrophonium in patients undergoing coronary artery bypass graft surgery.
Journal of cardiothoracic and vascular anesthesia 20021001
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A safe and noninvasive test for vagal integrity revisited.
Archives of surgery (Chicago, Ill. : 1960) 20020801
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[Ocular myasthenic syndrome and systemic lupus erythematosus].
Klinische Monatsblatter fur Augenheilkunde 20020701
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The effect of edrophonium on autonomic outflow.
Anesthesiology 20020301
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[What to do in case of acquired ptosis].
Journal francais d'ophtalmologie 20020301
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Oxyaniliniums as acetylcholinesterase inhibitors for the reversal of neuromuscular block.
Bioorganic & medicinal chemistry letters 20020121
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Effects of the anticholinesterase edrophonium on spectral analysis of heart rate and blood pressure variability in humans.
The Journal of pharmacology and experimental therapeutics 20020101
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[Myasthenia gravis].
La Revue du praticien 20020101
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[Technical consideration for repetitive nerve stimulation].
Rinsho shinkeigaku = Clinical neurology 20020101
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Reversal of mivacurium chloride: edrophonium of spontaneous recovery in microscopic laryngeal surgery.
Acta anaesthesiologica Sinica 20011201
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Asystole induced by edrophonium following beta blockade.
Neurology 20010828
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Edrophonium antagonism of cisatracurium-induced neuromuscular block: dose requirements in children and adults.
Anaesthesia and intensive care 20010801
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[Voice disorders caused by neurological diseases].
Revista de neurologia 20010701
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Thioflavin T is a fluorescent probe of the acetylcholinesterase peripheral site that reveals conformational interactions between the peripheral and acylation sites.
The Journal of biological chemistry 20010629
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Does 'butyrylization' of acetylcholinesterase through substitution of the six divergent aromatic amino acids in the active center gorge generate an enzyme mimic of butyrylcholinesterase?
Biochemistry 20010626
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The effect of cholinergic enhancement during filling cystometry: can edrophonium chloride be used as a provocative test for overactive bladder?
The Journal of urology 20010501
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Myasthenia gravis: an elusive diagnosis in older people.
Journal of the American Geriatrics Society 20010501
-
Interaction of edrophonium with muscarinic acetylcholine M2 and M3 receptors.
Anesthesiology 20010501
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Reversal of rocuronium with edrophonium during propofol versus sevoflurane anesthesia.
Acta anaesthesiologica Scandinavica 20010201
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A dose-response study of anticholinesterase drugs on contractile and phosphatidylinositol responses of rat trachea.
Anesthesia and analgesia 20010101
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Sustained esophageal contraction: a marker of esophageal chest pain identified by intraluminal ultrasonography.
Gastroenterology 19990101
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Catecholamine facilitated reentrant ventricular tachycardia: uncoupling of adenosine's antiadrenergic effects.
Journal of cardiovascular electrophysiology 19990101
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Synthesis and study of thiocarbonate derivatives of choline as potential inhibitors of acetylcholinesterase.
Journal of medicinal chemistry 19970912
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The effect of edrophonium chloride-induced chest pain on esophageal blood flow and motility.
Scandinavian journal of gastroenterology 19970201
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Fresh frozen plasma and edrophonium in a patient with a plasma cholinesterase deficiency.
Anaesthesia 19930601
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Persisting chloroquine-induced myasthenia?
Acta clinica Belgica 19910101
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Oculogyric crisis after the Tensilon test.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 19900101
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Prospective evaluation of high-dose bethanechol in investigation of esophageal chest pain.
Digestive diseases and sciences 19891101
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Glycopyrronium requirements for antagonism of the muscarinic side effects of edrophonium.
British journal of anaesthesia 19890101
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Positive response to edrophonium in death adder (Acanthophis antarcticus) envenomation.
Australian and New Zealand journal of medicine 19881001
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Edrophonium-hyoscine butylbromide mixture for reversal of neuromuscular blockade: heart rate changes in infants and children.
Anaesthesia 19880701
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Augmented anti-acetylcholine receptor response following long-term penicillamine administration.
Annals of neurology 19840701
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Cardiac arrest following treatment of paroxysmal atrial tachycardia with edrophonium.
Anesthesiology 19790301
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Ventricular asystole after edrophonium chloride administration.
JAMA 19760308
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Cardiac arrest during edrophonium administration.
American heart journal 19710301
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Recurarization--fact or fiction.
Anesthesia and analgesia 19710101