1160924-51-5 | (E)-tert-Butyl 4-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)piperidine-1-carboxylate

Packsize	Purity	Availability	Price	Discounted Price
100mg	97%	in stock	$43.00	$31.00
250mg	97%	in stock	$97.00	$68.00
1g	97%	in stock	$253.00	$178.00
5g	97%	in stock	$1,216.00	$852.00

Description

• Catalog Number: AV18831
• Chemical Name: (E)-tert-Butyl 4-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)piperidine-1-carboxylate
• CAS Number: 1160924-51-5
• Molecular Formula: C18H32BNO4
• Molecular Weight: 337.262
• MDL Number: MFCD28388343
• SMILES: O=C(N1CCC(CC1)/C=C/B1OC(C(O1)(C)C)(C)C)OC(C)(C)C

Computed Properties

• Complexity: 472
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 24
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4

Upstream Synthesis Route

The (E)-(2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)vinyl)boronic acid pinacol ester is a versatile compound commonly utilized in chemical synthesis for the formation of carbon-carbon bonds. This compound serves as a valuable building block in organic synthesis, particularly in the field of medicinal chemistry and drug development.One of the key applications of (E)-(2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)vinyl)boronic acid pinacol ester is its effectiveness in Suzuki-Miyaura cross-coupling reactions. By coupling this boronic acid pinacol ester with various aryl halides or pseudohalides in the presence of a palladium catalyst, chemists can efficiently construct complex organic molecules with high regio- and stereo-selectivity.Furthermore, the (E)-(2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)vinyl)boronic acid pinacol ester can also be employed in other types of carbon-carbon bond-forming reactions such as Heck and Sonogashira couplings. Its structural features make it a valuable tool for the synthesis of bioactive compounds, natural products, and pharmaceutical intermediates.In summary, the (E)-(2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)vinyl)boronic acid pinacol ester plays a crucial role in modern organic synthesis by enabling efficient and selective formation of carbon-carbon bonds, making it an indispensable component in the toolbox of synthetic chemists.