117-80-6 | 2,3-Dichloro-1,4-naphthoquinone

Packsize	Purity	Availability	Price	Discounted Price
25g	>95.0%(GC)	in stock	$20.00	$14.00
500g	>95.0%(GC)	in stock	$114.00	$80.00

Description

• Catalog Number: AA17303
• Chemical Name: 2,3-Dichloro-1,4-naphthoquinone
• CAS Number: 117-80-6
• Molecular Formula: C10H4Cl2O2
• Molecular Weight: 227.0436
• MDL Number: MFCD00001677
• SMILES: O=C1C(=C(Cl)C(=O)c2c1cccc2)Cl
• NSC Number: 537

Computed Properties

• Complexity: 301
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 2
• XLogP3: 3.4

Literature

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  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121201

• New oxirane derivatives of 1,4-naphthoquinones and their evaluation against T. cruzi epimastigote forms.

  Bioorganic & medicinal chemistry 20120815

• Incorporation of a high potential quinone reveals that electron transfer in Photosystem I becomes highly asymmetric at low temperature.

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• On the search for potential anti-Trypanosoma cruzi drugs: synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions.

  European journal of medicinal chemistry 20120601

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• Kinetics of jack bean urease inhibition by 2,3-dichloro-1,4-naphthoquinone. Elucidation of the mechanism: redox cycling and sulfhydryl arylation.

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• 2,3-Disubstituted-1,4-naphthoquinones, 12H-benzo[b]phenothiazine-6,11-diones and related compounds: synthesis and biological evaluation as potential antiproliferative and antifungal agents.

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• Charge transfer interaction of 4-acetamidophenol (paracetamol) with 2,3-dichloro-1,4-naphthoquinone: a study in aqueous ethanol medium by UV-vis spectroscopic and DFT methods.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081201

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• Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism.

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  The journal of physical chemistry. B 20071206

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• Interaction of 2,3-dichloro-1,4-naphthoquinone with n-butylamine in halocarbon solvents.

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• Selective growth-inhibiting effects of compounds identified in Tabebuia impetiginosa inner bark on human intestinal bacteria.

  Journal of agricultural and food chemistry 20050223

• Development and validation of spectrophotometric methods for determination of fluoxetine, sertraline, and paroxetine in pharmaceutical dosage forms.

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• Study of a reaction between 2,3-dichloro-1,4-naphthoquinone and N,N'-diphenyl thiourea involving an EDA adduct as intermediate.

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  Die Pharmazie 20030201

• 2-(Pyrrolidin-1-yl)-1,4-naphthoquinone and 2-phenylsulfanyl-3-(pyrrolidin-1-yl)-1,4-naphthoquinone.

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  Bioorganic & medicinal chemistry letters 19991004