117467-28-4 | Cefditoren Pivoxil

Packsize	Purity	Availability	Price	Discounted Price
5mg	98%(HPLC)	in stock	$33.00	$23.00
25mg	98%(HPLC)	in stock	$71.00	$50.00
250mg	≥98.0%(HPLC)	in stock	$116.00	$81.00
1g	≥98.0%(HPLC)	in stock	$225.00	$158.00
5g	≥98.0%(HPLC)	in stock	$630.00	$441.00
25g	≥98.0%(HPLC)	in stock	$2,361.00	$1,653.00

Description

• Catalog Number: AB71819
• Chemical Name: Cefditoren Pivoxil
• CAS Number: 117467-28-4
• Molecular Formula: C25H28N6O7S3
• Molecular Weight: 620.7208
• MDL Number: MFCD00933166
• SMILES: CO/N=C(/c1csc(n1)N)\C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)OCOC(=O)C(C)(C)C)/C=C\c1scnc1C

Computed Properties

• Complexity: 1160
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 2
• Defined Bond Stereocenter Count: 2
• Heavy Atom Count: 41
• Hydrogen Bond Acceptor Count: 14
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 12
• XLogP3: 4.7

Literature

• Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

  PLoS computational biology 20111201

• [Antibiotic therapy against acute tonsillopharyngitis in children due to group A beta-hemolytic streptococci: comparison of clinical efficacy, the bactericidal effects, and effects on oral flora between cefditoren pivoxil for 5 days and amoxicillin for 10 days].

  The Japanese journal of antibiotics 20110601

• [Evaluation of the safety and efficacy of cefditoren pivoxil fine granules for pediatric use in pediatric patients with laryngopharyngitis and tonsillitis caused by Streptococcus pyogenes].

  The Japanese journal of antibiotics 20100801

• [Evaluation of the safety and efficacy of cefditoren pivoxil fine granules for pediatric use in pediatric patients with acute otitis media].

  The Japanese journal of antibiotics 20100601

• [Pulmonary abscess due to Leuconostoc species in an immunocompetent patient].

  Archivos de bronconeumologia 20090901

• Effect of fluoroquinolones on body temperature of mice.

  The Journal of antimicrobial chemotherapy 20081201

• Efficacy of cefditoren pivoxil and amoxicillin/clavulanate in the treatment of pediatric patients with acute bacterial rhinosinusitis in Thailand: a randomized, investigator-blinded, controlled trial.

  Clinical therapeutics 20081001

• Efficient and eco-friendly preparation of 4-methyl-5-formyl-thiazole.

  Molecules (Basel, Switzerland) 20080421

• [A multicenter study of 7-day cefditoren pivoxil treatment for group A streptococcal infection].

  The Japanese journal of antibiotics 20071001

• Carnitine-associated encephalopathy caused by long-term treatment with an antibiotic containing pivalic acid.

  Pediatrics 20070901

• The efficacy of cefditoren pivoxil in the treatment of lower respiratory tract infections, with a focus on the per-pathogen bacteriologic response in infections caused by Streptococcus pneumoniae and Haemophilus influenzae: a pooled analysis of seven clinical trials.

  Clinical therapeutics 20061201

• [Cefditoren pivoxil: A new oral cephalosporin for skin, soft tissue and respiratory tract infections].

  Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20060901

• Effects of sugar ester and hydroxypropyl methylcellulose on the physicochemical stability of amorphous cefditoren pivoxil in aqueous suspension.

  International journal of pharmaceutics 20050216

• A study of the differences between two amorphous spray-dried samples of cefditoren pivoxil which exhibited different physical stabilities.

  International journal of pharmaceutics 20050131

• Spotlight on cefditoren pivoxil in bacterial infections.

  Treatments in respiratory medicine 20050101

• Precision and detection limit of quality test for amorphous drug in powder X-ray diffractometry.

  International journal of pharmaceutics 20040928

• Changes in surface properties by granulation and physicochemical stability of granulated amorphous cefditoren pivoxil with additives.

  International journal of pharmaceutics 20040806

• The use of inverse gas chromatography to assess the acid-base contributions to surface energies of cefditoren pivoxil and methacrylate copolymers and possible links to instability.

  International journal of pharmaceutics 20040319

• Determination of the changes in surface energetics of cefditoren pivoxil as a consequence of processing induced disorder and equilibration to different relative humidities.

  International journal of pharmaceutics 20040109

• Cefditoren pivoxil: a review of its use in the treatment of bacterial infections.

  Drugs 20040101

• Impact on carnitine homeostasis of short-term treatment with the pivalate prodrug cefditoren pivoxil.

  Clinical pharmacology and therapeutics 20030401

• [Efficacy and safety of cefditoren pivoxil in treatment of respiratory infections, a clinical study].

  Zhonghua yi xue za zhi 20030310

• Cefditoren pivoxil versus cefpodoxime proxetil for community-acquired pneumonia: results of a multicenter, prospective, randomized, double-blind study.

  Clinical therapeutics 20021101

• A comparison of cefditoren pivoxil and amoxicillin/ clavulanate in the treatment of community-acquired pneumonia: a multicenter, prospective, randomized, investigator-blinded, parallel-group study.

  Clinical therapeutics 20021101

• New drugs 2002, part III.

  Nursing 20020701

• Cefditoren pivoxil.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020301

• Antibiotic approval.

  The Nurse practitioner 20020201

• Spectracef. New cephalosporin antibiotic approved.

  Nursing 20020201

• Cefditoren pivoxil.

  Drugs 20020101