117519-13-8 | 6-Chloro-2-(trifluoromethyl)pyridin-3-amine

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$56.00	$40.00
1g	95%	in stock	$394.00	$276.00
5g	95%	in stock	$1,529.00	$1,070.00

Description

• Catalog Number: AI11078
• Chemical Name: 6-Chloro-2-(trifluoromethyl)pyridin-3-amine
• CAS Number: 117519-13-8
• Molecular Formula: C6H4ClF3N2
• Molecular Weight: 196.55756959999997
• MDL Number: MFCD18261523
• SMILES: Clc1ccc(c(n1)C(F)(F)F)N

Upstream Synthesis Route

6-Chloro-2-(trifluoromethyl)pyridin-3-amine is a versatile chemical compound widely used in chemical synthesis as a key building block. This compound serves as a valuable intermediate in the synthesis of various pharmaceuticals, agrochemicals, and specialty chemicals due to its unique structure and reactivity.In organic synthesis, 6-Chloro-2-(trifluoromethyl)pyridin-3-amine is often employed as a nucleophilic building block for the introduction of the trifluoromethyl group into target molecules. The trifluoromethyl group is known to enhance the bioactivity and metabolic stability of drug candidates, making it a desirable functional group in medicinal chemistry. Additionally, the chloro substituent on the pyridine ring can undergo various substitution reactions, allowing for further structural diversification.Moreover, the presence of an amine group in 6-Chloro-2-(trifluoromethyl)pyridin-3-amine enables facile derivatization through reductive amination, acylation, or condensation reactions, leading to the synthesis of a wide range of nitrogen-containing compounds. This versatility makes it a valuable tool for the construction of complex molecular architectures in organic synthesis.Overall, the strategic use of 6-Chloro-2-(trifluoromethyl)pyridin-3-amine in chemical synthesis offers synthetic chemists a practical and efficient route to access diverse molecular scaffolds with potential applications in drug discovery, material science, and beyond.