118-00-3 | Guanosine

Packsize	Purity	Availability	Price	Discounted Price
10g	98%	in stock	$6.00	$4.00
25g	98%	in stock	$7.00	$5.00
100g	98%	in stock	$18.00	$13.00
500g	98%	in stock	$80.00	$56.00

Description

• Catalog Number: AA23476
• Chemical Name: Guanosine
• CAS Number: 118-00-3
• Molecular Formula: C10H13N5O5
• Molecular Weight: 283.2407
• MDL Number: MFCD00149584
• SMILES: OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(N)[nH]c2=O

Computed Properties

• Complexity: 446
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 4
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 5
• Rotatable Bond Count: 2
• XLogP3: -1.9

Literature

• Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation.

  European journal of medicinal chemistry 20161129

• Guanosine exerts neuroprotective effects by reversing mitochondrial dysfunction in a cellular model of Parkinson's disease.

  International journal of molecular medicine 20141101

• Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC.

  Purinergic signalling 20121201

• The abasic site lesions in the human telomeric sequence d[TA(G(3)T(2)A)(3)G(3)]: a thermodynamic point of view.

  Biochimica et biophysica acta 20121201

• Synthesis and photophysical characterisation of a fluorescent nucleoside analogue that signals the presence of an abasic site in RNA.

  Chembiochem : a European journal of chemical biology 20121105

• Guanine nucleobase adducts formed by [Pt(di-(2-picolyl)amine)Cl]Cl: evidence that a tridentate ligand with only in-plane bulk can slow guanine base rotation.

  Inorganic chemistry 20121105

• Promotor polymorphisms of plasminogen activator inhibitor-1 and other thrombophilic genotypes in cerebral venous thrombosis: a case-control study in adults.

  Journal of neurology 20121101

• A new fluorometric assay for the study of DNA-binding and 3'-processing activities of retroviral integrases and its use for screening of HIV-1 integrase inhibitors.

  Biochimie 20121101

• Foxo3a targets mitochondria during guanosine 5'-triphosphate guided erythroid differentiation.

  The international journal of biochemistry & cell biology 20121101

• In vivo validation of DNA adduct formation by estragole in rats predicted by physiologically based biodynamic modelling.

  Mutagenesis 20121101

• Metabolite target analysis of human urine combined with pattern recognition techniques for the study of symptomatic gout.

  Molecular bioSystems 20121101

• Crystal structure analysis of the translation factor RF3 (release factor 3).

  FEBS letters 20121019

• tRNA processing by protein-only versus RNA-based RNase P: kinetic analysis reveals mechanistic differences.

  Chembiochem : a European journal of chemical biology 20121015

• Factors that influence the antiproliferative activity of half sandwich Ru(II)-[9]aneS3 coordination compounds: activation kinetics and interaction with guanine derivatives.

  Dalton transactions (Cambridge, England : 2003) 20121014

• Lead(II)-catalyzed oxidation of guanine in solution studied with electrospray ionization mass spectrometry.

  The journal of physical chemistry. B 20121004

• Nucleoside analogue electrochemical behaviour and in situ evaluation of DNA-clofarabine interaction.

  Bioelectrochemistry (Amsterdam, Netherlands) 20121001

• Effects of chronic guanosine treatment on hippocampal damage and cognitive impairment of rats submitted to chronic cerebral hypoperfusion.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20121001

• Combining redox-proteomics and epigenomics to explain the involvement of oxidative stress in psychiatric disorders.

  Molecular bioSystems 20121001

• Guanosine produces an antidepressant-like effect through the modulation of NMDA receptors, nitric oxide-cGMP and PI3K/mTOR pathways.

  Behavioural brain research 20121001

• Identification and expression profiles of ADAR1 gene, responsible for RNA editing, in responses to dsRNA and GCRV challenge in grass carp (Ctenopharyngodon idella).

  Fish & shellfish immunology 20121001

• Eukaryotic initiation factor 5B: a new player for the anti-hepatitis C virus effect of ribavirin?

  Medical hypotheses 20121001

• In vivo and in vitro animal investigation of the effect of a mixture of herbal extracts from Tribulus terrestris and Cornus officinalis on penile erection.

  The journal of sexual medicine 20121001

• C8-linked bulky guanosine DNA adducts: experimental and computational insights into adduct conformational preferences and resulting mutagenicity.

  Future medicinal chemistry 20121001

• Filament formation of the FtsZ/tubulin-like protein TubZ from the Bacillus cereus pXO1 plasmid.

  The Journal of biological chemistry 20120914

• Benchmark studies on the building blocks of DNA. 2. Effect of biological environment on the electronic excitation spectrum of nucleobases.

  The journal of physical chemistry. A 20120906

• Oxidative damage of DNA, RNA and their metabolites in leukocytes, plasma and urine of Macaca mulatta: 8-oxoguanosine in urine is a useful marker for aging.

  Free radical research 20120901

• Sex differences in the Nociceptin/Orphanin FQ system in rat spinal cord following chronic morphine treatment.

  Neuropharmacology 20120901

• The mu opioid receptor modulates neurotransmission in the rat spinal ventral horn.

  Anesthesia and analgesia 20120901

• Sphingosine 1-phosphate receptor 2 antagonist JTE-013 increases the excitability of sensory neurons independently of the receptor.

  Journal of neurophysiology 20120901

• Cooperation of non-effective concentration of glutamatergic system modulators and antioxidant against oxidative stress induced by quinolinic acid.

  Neurochemical research 20120901

• Mycophenolate mofetil inhibits hepatitis C virus replication in human hepatic cells.

  Virus research 20120901

• Box H/ACA snoRNAs are preferred substrates for the trimethylguanosine synthase in the divergent unicellular eukaryote Trichomonas vaginalis.

  RNA (New York, N.Y.) 20120901

• Recognition of guanosine by dissimilar tRNA methyltransferases.

  RNA (New York, N.Y.) 20120901

• High genomic instability predicts survival in metastatic high-risk neuroblastoma.

  Neoplasia (New York, N.Y.) 20120901

• TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification.

  Science (New York, N.Y.) 20120831

• Characterization of heterotrimeric nucleotide-depleted Gα(i)-proteins by Bodipy-FL-GTPγS fluorescence anisotropy.

  Archives of biochemistry and biophysics 20120815

• RNA oxidation catalyzed by cytochrome c leads to its depurination and cross-linking, which may facilitate cytochrome c release from mitochondria.

  Free radical biology & medicine 20120815

• A new imidazolium-embedded C18 stationary phase with enhanced performance in reversed-phase liquid chromatography.

  Analytica chimica acta 20120813

• Thermodynamics of the GTP-GDP-operated conformational switch of selenocysteine-specific translation factor SelB.

  The Journal of biological chemistry 20120810

• Protective effects of guanosine against sepsis-induced damage in rat brain and cognitive impairment.

  Brain, behavior, and immunity 20120801

• An intravaginal ring for the simultaneous delivery of multiple drugs.

  Journal of pharmaceutical sciences 20120801

• Mitofusins and the mitochondrial permeability transition: the potential downside of mitochondrial fusion.

  American journal of physiology. Heart and circulatory physiology 20120801

• Activation of heme oxygenase and suppression of cGMP are associated with impaired endothelial function in obstructive sleep apnea with hypertension.

  American journal of hypertension 20120801

• Interaction of liposome-encapsulated cisplatin with biomolecules.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20120801

• Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway.

  Neurochemistry international 20120801

• Synthesis and in vitro stability of nucleoside 5'-phosphonate derivatives.

  European journal of medicinal chemistry 20120801

• Intractable absence seizures in hyperinsulinism-hyperammonemia syndrome.

  Pediatric neurology 20120801

• Increased gene expression of the ABCC5 transporter without distinct changes in the expression of PDE5 in human cervical cancer cells during growth.

  Anticancer research 20120801

• Nascent-seq indicates widespread cotranscriptional RNA editing in Drosophila.

  Molecular cell 20120713

• Differential regulation by cyclic nucleotides of the CNGA4 and CNGB1b subunits in olfactory cyclic nucleotide-gated channels.

  Science signaling 20120710

• Solution structure of the N-terminal dsRBD of Drosophila ADAR and interaction studies with RNA.

  Biochimie 20120701

• Development of operational models of receptor activation including constitutive receptor activity and their use to determine the efficacy of the chemokine CCL17 at the CC chemokine receptor CCR4.

  British journal of pharmacology 20120701

• The histamine autoreceptor is a short isoform of the H₃ receptor.

  British journal of pharmacology 20120701

• Sar1 translocation onto the ER-membrane for vesicle budding has different pathways for promotion and suppression of ER-to-Golgi transport mediated through H89-sensitive kinase and ER-resident G protein.

  Molecular and cellular biochemistry 20120701

• Next-generation sequencing offers new insights into DNA degradation.

  Trends in biotechnology 20120701

• Stacked and continuous helical self-assemblies of guanosine monophosphates detected by vibrational circular dichroism.

  Analytical and bioanalytical chemistry 20120701

• Detection and typing of viruses using broadly sensitive cocktail-PCR and mass spectrometric cataloging: demonstration with dengue virus.

  The Journal of molecular diagnostics : JMD 20120701

• Retinal remodeling.

  Japanese journal of ophthalmology 20120701

• Estrogen receptor alpha modulates Toll-like receptor signaling in murine lupus.

  Clinical immunology (Orlando, Fla.) 20120701

• Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system.

  Nature structural & molecular biology 20120701

• Dose-dependent response of dendritic cells to 7-thia-8-oxo-guanosine and its modulation by polyinosinic:polycytidylic acid.

  Experimental biology and medicine (Maywood, N.J.) 20120701

• Identification of interaction partners of the dynamin-like protein DynA from Bacillus subtilis.

  Communicative & integrative biology 20120701

• Cyclic di-GMP sensing via the innate immune signaling protein STING.

  Molecular cell 20120629

• New quinoxaline derivatives as potential MT₁ and MT₂ receptor ligands.

  Molecules (Basel, Switzerland) 20120625

• Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP.

  Nature structural & molecular biology 20120624

• Potential of the NBP method for the study of alkylation mechanisms: NBP as a DNA-model.

  Chemical research in toxicology 20120618

• Tax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cells.

  The Journal of biological chemistry 20120615

• Human MTH3 (NUDT18) protein hydrolyzes oxidized forms of guanosine and deoxyguanosine diphosphates: comparison with MTH1 and MTH2.

  The Journal of biological chemistry 20120615

• Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors.

  Science signaling 20120605

• Transcriptional profile of GTP-mediated differentiation of C2C12 skeletal muscle cells.

  Purinergic signalling 20120601

• Collection and storage of red blood cells with anticoagulant and additive solution with a physiologic pH.

  Transfusion 20120601

• The regulation of cardiac activity by nitric oxide (NO) in the Vietnamese stick insect, Baculum extradentatum.

  Cellular signalling 20120601

• Distinct pattern of oxidative DNA damage and DNA repair in follicular thyroid tumours.

  Journal of molecular endocrinology 20120601

• Novel role of NF-κB-p65 in antioxidant homeostasis in human kidney-2 cells.

  American journal of physiology. Renal physiology 20120601

• Computational insights into the inhibition of inosine 5'-monophosphate dehydrogenase by mycophenolic acid analogs: three-dimensional quantitative structure-activity relationship and molecular docking studies.

  Chemical biology & drug design 20120601

• Receptor conformations involved in dopamine D(2L) receptor functional selectivity induced by selected transmembrane-5 serine mutations.

  Molecular pharmacology 20120601

• Adenosine modification may be preferred for reducing siRNA immune stimulation.

  Nucleic acid therapeutics 20120601

• Deep EST profiling of developing fenugreek endosperm to investigate galactomannan biosynthesis and its regulation.

  Plant molecular biology 20120601

• Fluorometric detection of adenine in target DNA by exciplex formation with fluorescent 8-arylethynylated deoxyguanosine.

  Bioorganic & medicinal chemistry letters 20120601

• Exploring purine N7 interactions via atomic mutagenesis: the group I ribozyme as a case study.

  RNA (New York, N.Y.) 20120601

• A novel sulindac derivative that potently suppresses colon tumor cell growth by inhibiting cGMP phosphodiesterase and β-catenin transcriptional activity.

  Cancer prevention research (Philadelphia, Pa.) 20120601

• E2F1-dependent methyl cap formation requires RNA pol II phosphorylation.

  Cell cycle (Georgetown, Tex.) 20120601

• The circadian neuropeptide PDF signals preferentially through a specific adenylate cyclase isoform AC3 in M pacemakers of Drosophila.

  PLoS biology 20120601

• Two-step, one-pot synthesis of inosine, guanosine, and 2'-deoxyguanosine O6-ethers via intermediate O6-(benzotriazol-1-yl) derivatives.

  Current protocols in nucleic acid chemistry 20120601

• Bridging QTAIM with vibrational spectroscopy: the energy of intramolecular hydrogen bonds in DNA-related biomolecules.

  Physical chemistry chemical physics : PCCP 20120528

• Ionic liquids promote PCR amplification of DNA.

  Chemical communications (Cambridge, England) 20120528

• The DNA damage checkpoint protein ATM promotes hepatocellular apoptosis and fibrosis in a mouse model of non-alcoholic fatty liver disease.

  Cell cycle (Georgetown, Tex.) 20120515

• Signal transduction pathway activity compensates dopamine D₂/D₃ receptor density changes in Parkinson's disease: a preliminary comparative human brain receptor autoradiography study with [³H]raclopride and [³⁵S]GTPγS.

  Brain research 20120509

• Diffusion and birefringence of bioactive dyes in a supramolecular guanosine hydrogel.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20120507

• Exploring light and life.

  The Journal of biological chemistry 20120504

• A-to-I editing of microRNAs: regulating the regulators?

  Seminars in cell & developmental biology 20120501

• Sensitivity to μ-opioid receptor-mediated anti-nociception is determined by cross-regulation between μ- and δ-opioid receptors at supraspinal level.

  British journal of pharmacology 20120501

• The intricate relationship between RNA structure, editing, and splicing.

  Seminars in cell & developmental biology 20120501

• Lysophosphatidylinositol stimulates [³⁵S]GTPγS binding in the rat prefrontal cortex and hippocampus.

  Neurochemical research 20120501

• Hydrostatic and osmotic pressure study of the RNA hydration.

  Molecular biology reports 20120501

• Acetylcholine-evoked afterdischarge in Aplysia bag cell neurons.

  Journal of neurophysiology 20120501

• Age-dependent increases in the oxidative damage of DNA, RNA, and their metabolites in normal and senescence-accelerated mice analyzed by LC-MS/MS: urinary 8-oxoguanosine as a novel biomarker of aging.

  Free radical biology & medicine 20120501

• Synthesis and biological evaluation of a series of thieno-expanded tricyclic purine 2'-deoxy nucleoside analogues.

  Bioorganic & medicinal chemistry 20120501

• Novel peptide for attenuation of hypoxia-induced pulmonary hypertension via modulation of nitric oxide release and phosphodiesterase -5 activity.

  Peptides 20120501

• Enzymatic synthesis of 8-vinyl- and 8-styryl-2'-deoxyguanosine modified DNA--novel fluorescent molecular probes.

  Bioorganic & medicinal chemistry letters 20120501

• Statistical parametric mapping reveals regional alterations in cannabinoid CB1 receptor distribution and G-protein activation in the 3D reconstructed epileptic rat brain.

  Epilepsia 20120501

• Supramolecular arrangement of guanosine/5-guanosine monophosphate binary mixtures studied by methods of circular dichroism.

  Chirality 20120501

• Structure and functional analysis of the RNA- and viral phosphoprotein-binding domain of respiratory syncytial virus M2-1 protein.

  PLoS pathogens 20120501

• Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors.

  Journal of medicinal chemistry 20120426

• Signaling property study of adhesion G-protein-coupled receptors.

  FEBS letters 20120424

• β-arrestin2 regulates cannabinoid CB1 receptor signaling and adaptation in a central nervous system region-dependent manner.

  Biological psychiatry 20120415

• Structural basis for dual nucleotide selectivity of aminoglycoside 2''-phosphotransferase IVa provides insight on determinants of nucleotide specificity of aminoglycoside kinases.

  The Journal of biological chemistry 20120413

• Allosteric modulator ORG27569 induces CB1 cannabinoid receptor high affinity agonist binding state, receptor internalization, and Gi protein-independent ERK1/2 kinase activation.

  The Journal of biological chemistry 20120406

• Geissoschizine methyl ether, an alkaloid in Uncaria hook, is a potent serotonin ₁A receptor agonist and candidate for amelioration of aggressiveness and sociality by yokukansan.

  Neuroscience 20120405

• Assignments of backbone ¹H, ¹³C and ¹⁵N resonances in H-Ras (1-166) complexed with GppNHp at physiological pH.

  Biomolecular NMR assignments 20120401

• In vivo characterization of several rodent glioma models by 1H MRS.

  NMR in biomedicine 20120401

• DNA damage in lead-exposed hepatocytes: coexistence of apoptosis and necrosis?

  Drug and chemical toxicology 20120401

• Hormonal control of mammalian oocyte meiosis at diplotene stage.

  Cellular and molecular life sciences : CMLS 20120401

• Induction of apoptosis by type Iβ protein kinase G in the human breast cancer cell lines MCF-7 and MDA-MB-468.

  Cell biochemistry and function 20120401

• Selective recognition and separation of nucleosides using carboxymethyl-β-cyclodextrin functionalized hybrid magnetic nanoparticles.

  Colloids and surfaces. B, Biointerfaces 20120401

• Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats.

  Critical care medicine 20120401

• Probes for narcotic receptor mediated phenomena. 44. Synthesis of an N-substituted 4-hydroxy-5-(3-hydroxyphenyl)morphan with high affinity and selective μ-antagonist activity.

  European journal of medicinal chemistry 20120401

• Mechanism of substrate selection by a highly specific CRISPR endoribonuclease.

  RNA (New York, N.Y.) 20120401

• The synthesis of 2'-methylseleno adenosine and guanosine 5'-triphosphates.

  Bioorganic & medicinal chemistry 20120401

• Separation of nucleobases and their derivatives with organic-high ionic strength aqueous phase systems by spiral high-speed counter-current chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120401

• Loxoribine pretreatment reduces Salmonella Enteritidis organ invasion in 1-day-old chickens.

  Poultry science 20120401

• A RelA-dependent two-tiered regulated proteolysis cascade controls synthesis of a contact-dependent intercellular signal in Myxococcus xanthus.

  Molecular microbiology 20120401

• Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER.

  Acta crystallographica. Section D, Biological crystallography 20120401

• Structural basis for type VI secretion effector recognition by a cognate immunity protein.

  PLoS pathogens 20120401

• The Caenorhabditis elegans HEN1 ortholog, HENN-1, methylates and stabilizes select subclasses of germline small RNAs.

  PLoS genetics 20120401

• First total synthesis of a naturally occurring iodinated 5'-deoxyxylofuranosyl marine nucleoside.

  Marine drugs 20120401

• [Dynamic accumulation of dry matter and active element in Pinellia ternata of Taizhou].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120401

• Effects of ginsenoside on pacemaker potentials of cultured interstitial cells of Cajal clusters from the small intestine of mice.

  Molecules and cells 20120331

• The structural basis of the kinetic mechanism of a gap-filling X-family DNA polymerase that binds Mg(2+)-dNTP before binding to DNA.

  Journal of molecular biology 20120330

• The butter flavorant, diacetyl, forms a covalent adduct with 2-deoxyguanosine, uncoils DNA, and leads to cell death.

  Journal of agricultural and food chemistry 20120328

• δ-opioid receptor function in the dorsal striatum plays a role in high levels of ethanol consumption in rats.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20120328

• 2'-Azido RNA, a versatile tool for chemical biology: synthesis, X-ray structure, siRNA applications, click labeling.

  ACS chemical biology 20120316

• Preparation of methacrylate-based monolith for capillary hydrophilic interaction chromatography and its application in determination of nucleosides in urine.

  Journal of chromatography. A 20120309

• Biochemical characterization of ribosome assembly GTPase RbgA in Bacillus subtilis.

  The Journal of biological chemistry 20120309

• Properties of an LNA-modified ricin RNA aptamer.

  Biochemical and biophysical research communications 20120302

• The delta opioid receptor antagonist, SoRI-9409, decreases yohimbine stress-induced reinstatement of ethanol-seeking.

  Addiction biology 20120301

• YQA14: a novel dopamine D3 receptor antagonist that inhibits cocaine self-administration in rats and mice, but not in D3 receptor-knockout mice.

  Addiction biology 20120301

• Increased ethanol intake in prodynorphin knockout mice is associated to changes in opioid receptor function and dopamine transmission.

  Addiction biology 20120301

• Synthesis of novel Eu(III) luminescent probe based on 9- acridinecarboxylic acid skelton for sensing of ds-DNA.

  Journal of fluorescence 20120301

• Wild-type and feedback-resistant phosphoribosyl pyrophosphate synthetases from Bacillus amyloliquefaciens: purification, characterization, and application to increase purine nucleoside production.

  Applied microbiology and biotechnology 20120301

• [(35)S]GTPγS binding and opioid tolerance and efficacy in mouse spinal cord.

  Pharmacology, biochemistry, and behavior 20120301

• Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA(B) receptor.

  The Journal of pharmacology and experimental therapeutics 20120301

• Modulation of guanosine nucleotides biosynthetic pathways enhanced GDP-L-fucose production in recombinant Escherichia coli.

  Applied microbiology and biotechnology 20120301

• Epigenetic modifications in cardiovascular disease.

  Basic research in cardiology 20120301

• The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons.

  Journal of neuropathology and experimental neurology 20120301

• Two-step efficient synthesis of 5-methyluridine via two thermostable nucleoside phosphorylase from Aeropyrum pernix.

  Bioorganic & medicinal chemistry letters 20120301

• A corrected space group for Sulfolobus sulfataricus 5'-deoxy-5'-methylthioadenosine phosphorylase II.

  Acta crystallographica. Section D, Biological crystallography 20120301

• Short ORF-dependent ribosome shunting operates in an RNA picorna-like virus and a DNA pararetrovirus that cause rice tungro disease.

  PLoS pathogens 20120301

• Two programmed cell death systems in Escherichia coli: an apoptotic-like death is inhibited by the mazEF-mediated death pathway.

  PLoS biology 20120301

• Quantitative Proteomics of Intracellular Campylobacter jejuni Reveals Metabolic Reprogramming.

  PLoS pathogens 20120301

• Statistical analysis of readthrough levels for nonsense mutations in mammalian cells reveals a major determinant of response to gentamicin.

  PLoS genetics 20120301

• B-type natriuretic Peptide assay for the diagnosis and prognosis of patent ductus arteriosus in preterm infants.

  Korean circulation journal 20120301

• Online extraction and isolation of highly polar chemical constituents from Brassica napus L. pollen by high shear technique coupled with high-performance counter-current chromatography.

  Journal of separation science 20120301

• Pharmacokinetics of mycophenolic acid and its phenyl glucuronide metabolite in kidney transplant recipients with renal impairment.

  Archives of medical science : AMS 20120227

• Aberrant cyclization affords a C-6 modified cyclic adenosine 5'-diphosphoribose analogue with biological activity in Jurkat T cells.

  Journal of medicinal chemistry 20120223

• Oxidation of the antiviral drug acyclovir and its biodegradation product carboxy-acyclovir with ozone: kinetics and identification of oxidation products.

  Environmental science & technology 20120221

• Selection of monoclonal antibodies against 6-oxo-M(1)dG and their use in an LC-MS/MS assay for the presence of 6-oxo-M(1)dG in vivo.

  Chemical research in toxicology 20120220

• Supramolecular dendrimers: convenient synthesis by programmed self-assembly and tunable thermoresponsivity.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20120220

• Diversity of archaeosine synthesis in crenarchaeota.

  ACS chemical biology 20120217

• Biochemical identification of a hydroperoxide derivative of the free 8-oxo-7,8-dihydroguanine base.

  Free radical biology & medicine 20120215

• Base pairing at the abasic site in DNA duplexes and its application in adenosine aptasensors.

  Chembiochem : a European journal of chemical biology 20120213

• Ras-related GTPases Rap1 and RhoA collectively induce the phagocytosis of serum-opsonized zymosan particles in macrophages.

  The Journal of biological chemistry 20120210

• Short-RNA selective binding of oligonucleotides modified using adenosine and guanosine derivatives that possess cyclohexyl phosphates as substituents.

  Organic & biomolecular chemistry 20120207

• High constitutive activity is an intrinsic feature of ghrelin receptor protein: a study with a functional monomeric GHS-R1a receptor reconstituted in lipid discs.

  The Journal of biological chemistry 20120203

• A nucleotide phosphatase activity in the nucleotide binding domain of an orphan resistance protein from rice.

  The Journal of biological chemistry 20120203

• Oxidative damage to guanine nucleosides following combination chemotherapy with 5-fluorouracil and oxaliplatin.

  Cancer chemotherapy and pharmacology 20120201

• Nitric oxide synthase and cyclic GMP signaling in cardiac myocytes: from contractility to remodeling.

  Journal of molecular and cellular cardiology 20120201

• Chronic treatment with the opioid antagonist naltrexone favours the coupling of spinal cord μ-opioid receptors to Gαz protein subunits.

  Neuropharmacology 20120201

• 3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²⁺ desensitization in permeabilized rat mesenteric artery.

  Naunyn-Schmiedeberg's archives of pharmacology 20120201

• Formation and characterization of covalent guanosine adducts with electrochemistry-liquid chromatography-mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120201

• The basic property of Lys385 is important for potentiation of the human α1 glycine receptor by ethanol.

  The Journal of pharmacology and experimental therapeutics 20120201

• 3-Substituted pyrazole analogs of the cannabinoid type 1 (CB₁) receptor antagonist rimonabant: cannabinoid agonist-like effects in mice via non-CB₁, non-CB₂ mechanism.

  The Journal of pharmacology and experimental therapeutics 20120201

• Muscarinic receptor/G-protein coupling is reduced in the dorsomedial striatum of cognitively impaired aged rats.

  Behavioural brain research 20120201

• Mechanisms of systemic vasodilation by lysozyme-c in septic shock.

  Journal of applied physiology (Bethesda, Md. : 1985) 20120201

• Analyzing the metabolic stress response of recombinant Escherichia coli cultures expressing human interferon-beta in high cell density fed batch cultures using time course transcriptomic data.

  Molecular bioSystems 20120201

• Identification and characterization of mutations in the promoter region of the factor VIII gene.

  Journal of thrombosis and haemostasis : JTH 20120201

• Structures of NodZ α1,6-fucosyltransferase in complex with GDP and GDP-fucose.

  Acta crystallographica. Section D, Biological crystallography 20120201

• Chemical fingerprint analysis of Fritillaria delavayi Franch. by high-performance liquid chromatography.

  Journal of separation science 20120201

• An optimized electrochemistry-liquid chromatography-mass spectrometry method for studying guanosine oxidation.

  Electrophoresis 20120201

• Characterization of RNA damage under oxidative stress in Escherichia coli.

  Biological chemistry 20120201

• Functional promiscuity of the COG0720 family.

  ACS chemical biology 20120120

• Oligomer formation of the bacterial second messenger c-di-GMP: reaction rates and equilibrium constants indicate a monomeric state at physiological concentrations.

  Journal of the American Chemical Society 20120118

• The inverse agonist effect of rimonabant on G protein activation is not mediated by the cannabinoid CB1 receptor: evidence from postmortem human brain.

  Biochemical pharmacology 20120115

• Lung endothelial Ca2+ and permeability response to platelet-activating factor is mediated by acid sphingomyelinase and transient receptor potential classical 6.

  American journal of respiratory and critical care medicine 20120115

• R-Isovaline: a subtype-specific agonist at GABA(B)-receptors?

  Neuroscience 20120110

• Hydrogen sulfide as a cryogenic mediator of hypoxia-induced anapyrexia.

  Neuroscience 20120110

• Kinetic analysis of 3'-5' nucleotide addition catalyzed by eukaryotic tRNA(His) guanylyltransferase.

  Biochemistry 20120110

• In vitro selection and characterization of a novel Zn(II)-dependent phosphorothiolate thiolesterase ribozyme.

  Biochemistry 20120110

• The combination of organoselenium compounds and guanosine prevents glutamate-induced oxidative stress in different regions of rat brains.

  Brain research 20120109

• SK channel modulation rescues striatal plasticity and control over habit in cannabinoid tolerance.

  Nature neuroscience 20120108

• Enhancement of affinity in molecular recognition via hydrogen bonds by POSS-core dendrimer and its application for selective complex formation between guanosine triphosphate and 1,8-naphthyridine derivatives.

  Organic & biomolecular chemistry 20120107

• Incoherent feedforward control governs adaptation of activated ras in a eukaryotic chemotaxis pathway.

  Science signaling 20120103

• Erectogenic Effects of Clerodendron capitatum: Involvement of Phosphodiesterase Type-5 Inhibition.

  Evidence-based complementary and alternative medicine : eCAM 20120101

• Modulation of microRNA expression and function by ADARs.

  Current topics in microbiology and immunology 20120101

• Interdependency of cystathione γ-lyase and cystathione β-synthase in hydrogen sulfide-induced blood pressure regulation in rats.

  American journal of hypertension 20120101

• Toll-like receptor 7 ligands inhibit influenza A infection in chickens.

  Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20120101

• Evidence that hyperprolinemia alters glutamatergic homeostasis in rat brain: neuroprotector effect of guanosine.

  Neurochemical research 20120101

• GABAB receptor-positive modulators: brain region-dependent effects.

  The Journal of pharmacology and experimental therapeutics 20120101

• The relaxation effect and mechanism of action of higenamine in the rat corpus cavernosum.

  International journal of impotence research 20120101

• Protein Glycosylation in Aspergillus fumigatus Is Essential for Cell Wall Synthesis and Serves as a Promising Model of Multicellular Eukaryotic Development.

  International journal of microbiology 20120101

• Oxidative stress, mitochondrial dysfunction, and aging.

  Journal of signal transduction 20120101

• Probe dependence in the allosteric modulation of a G protein-coupled receptor: implications for detection and validation of allosteric ligand effects.

  Molecular pharmacology 20120101

• CEP-26401 (irdabisant), a potent and selective histamine H₃ receptor antagonist/inverse agonist with cognition-enhancing and wake-promoting activities.

  The Journal of pharmacology and experimental therapeutics 20120101

• Protection from myocardial ischemia/reperfusion injury by a positive allosteric modulator of the A₃ adenosine receptor.

  The Journal of pharmacology and experimental therapeutics 20120101

• Inhibition of Junin virus RNA synthesis by an antiviral acridone derivative.

  Antiviral research 20120101

• Oligodeoxynucleotides inhibit Toll-like receptor 3 mediated cytotoxicity and CXCL8 release in keratinocytes.

  Experimental dermatology 20120101

• Identification of the muscarinic pathway underlying cessation of sleep-related burst activity in rat thalamocortical relay neurons.

  Pflugers Archiv : European journal of physiology 20120101

• Asymmetry of 13C labeled 3-pyruvate affords improved site specific labeling of RNA for NMR spectroscopy.

  Journal of biomolecular NMR 20120101

• ppGpp inhibits peptide elongation cycle of chloroplast translation system in vitro.

  Plant molecular biology 20120101

• Genetics and Gene Expression Involving Stress and Distress Pathways in Fibromyalgia with and without Comorbid Chronic Fatigue Syndrome.

  Pain research and treatment 20120101

• A new proofreading mechanism for lesion bypass by DNA polymerase-λ.

  EMBO reports 20120101

• Blocking type I interferon production: a new therapeutic option to reduce the HIV-1-induced immune activation.

  Clinical & developmental immunology 20120101

• Advancements in Z-DNA: development of inducers and stabilizers for B to Z transition.

  Current medicinal chemistry 20120101

• A computational perspective of molecular interactions through virtual screening, pharmacokinetic and dynamic prediction on ribosome toxin A chain and inhibitors of Ricinus communis.

  Pharmacognosy research 20120101

• Effects of inhaled nitric oxide on hemostasis in healthy adults treated with heparin: a randomized, controlled, blinded crossover study.

  Thrombosis journal 20120101

• Posttranscriptional recoding by RNA editing.

  Advances in protein chemistry and structural biology 20120101

• Antisense sequencing improves the accuracy and precision of A-to-I editing measurements using the peak height ratio method.

  BMC research notes 20120101

• Tyrosine nitration of PA700 links proteasome activation to endothelial dysfunction in mouse models with cardiovascular risk factors.

  PloS one 20120101

• HIV-1 polymerase inhibition by nucleoside analogs: cellular- and kinetic parameters of efficacy, susceptibility and resistance selection.

  PLoS computational biology 20120101

• Platelet inhibition by nitrite is dependent on erythrocytes and deoxygenation.

  PloS one 20120101

• The ζ toxin induces a set of protective responses and dormancy.

  PloS one 20120101

• Differential treatment regimen-related effects of HU210 on CB(1) and D(2)-like receptor functionality in the rat basal ganglia.

  Pharmacology 20120101

• Non coding RNAs and viruses in the framework of the phylogeny of the genes, epigenesis and heredity.

  International journal of molecular sciences 20120101

• A case of persistent foot pain in a neurofibromatosis type I patient.

  Case reports in medicine 20120101

• Insertion site preference of Mu, Tn5, and Tn7 transposons.

  Mobile DNA 20120101

• Complexity of murine cardiomyocyte miRNA biogenesis, sequence variant expression and function.

  PloS one 20120101

• Chemical approaches for structure and function of RNA in postgenomic era.

  Journal of nucleic acids 20120101

• Cystinosin, MPDU1, SWEETs and KDELR belong to a well-defined protein family with putative function of cargo receptors involved in vesicle trafficking.

  PloS one 20120101

• Gene profile of myeloid-derived suppressive cells from the bone marrow of lysosomal acid lipase knock-out mice.

  PloS one 20120101

• NCAM180 regulates Ric8A membrane localization and potentiates β-adrenergic response.

  PloS one 20120101

• Active site mutations change the cleavage specificity of neprilysin.

  PloS one 20120101

• Specific Cooperation Between Imp-α2 and Imp-β/Ketel in Spindle Assembly During Drosophila Early Nuclear Divisions.

  G3 (Bethesda, Md.) 20120101

• Discovery of inhibitors of Leishmania β-1,2-mannosyltransferases using a click-chemistry-derived guanosine monophosphate library.

  PloS one 20120101

• On docking, scoring and assessing protein-DNA complexes in a rigid-body framework.

  PloS one 20120101

• CSF concentrations of cAMP and cGMP are lower in patients with Creutzfeldt-Jakob disease but not Parkinson's disease and amyotrophic lateral sclerosis.

  PloS one 20120101

• Epigenetic disregulation in oral cancer.

  International journal of molecular sciences 20120101

• Expression of Tas1 taste receptors in mammalian spermatozoa: functional role of Tas1r1 in regulating basal Ca²⁺ and cAMP concentrations in spermatozoa.

  PloS one 20120101

• Menopausal status modifies breast cancer risk associated with the myeloperoxidase (MPO) G463A polymorphism in Caucasian women: a meta-analysis.

  PloS one 20120101

• Suppression of ribosomal protein synthesis and protein translation factors by Peg-interferon alpha/ribavirin in HCV patients blood mononuclear cells (PBMC).

  Journal of translational medicine 20120101

• Direct Antioxidant Properties of Bilirubin and Biliverdin. Is there a Role for Biliverdin Reductase?

  Frontiers in pharmacology 20120101

• Reversal of cocaine-conditioned place preference through methyl supplementation in mice: altering global DNA methylation in the prefrontal cortex.

  PloS one 20120101

• Reversal of the ΔdegP phenotypes by a novel rpoE allele of Escherichia coli.

  PloS one 20120101

• Dynamic 5-HT2C receptor editing in a mouse model of obesity.

  PloS one 20120101

• Nebivolol: impact on cardiac and endothelial function and clinical utility.

  Vascular health and risk management 20120101

• Hesperetin, a Selective Phosphodiesterase 4 Inhibitor, Effectively Suppresses Ovalbumin-Induced Airway Hyperresponsiveness without Influencing Xylazine/Ketamine-Induced Anesthesia.

  Evidence-based complementary and alternative medicine : eCAM 20120101

• Comparison of the effects of adenosine, inosine, and their combination as an adjunct to reperfusion in the treatment of acute myocardial infarction.

  ISRN cardiology 20120101

• Tissue distribution and metabolism of guanosine in rats following intraperitoneal injection.

  Journal of biological regulators and homeostatic agents 20120101

• Identification of novel Mt-Guab2 inhibitor series active against M. tuberculosis.

  PloS one 20120101

• The protein partners of GTP cyclohydrolase I in rat organs.

  PloS one 20120101

• Temporal patterns of nucleotide misincorporations and DNA fragmentation in ancient DNA.

  PloS one 20120101

• Spironolactone lowers portal hypertension by inhibiting liver fibrosis, ROCK-2 activity and activating NO/PKG pathway in the bile-duct-ligated rat.

  PloS one 20120101

• Stimulators and activators of soluble guanylate cyclase: review and potential therapeutic indications.

  Critical care research and practice 20120101

• Silencing of amyloid precursor protein expression using a new engineered delta ribozyme.

  International journal of Alzheimer's disease 20120101

• Development of on-line high performance liquid chromatography (HPLC)-biochemical detection methods as tools in the identification of bioactives.

  International journal of molecular sciences 20120101

• The Immune Response to Trypanosoma cruzi: Role of Toll-Like Receptors and Perspectives for Vaccine Development.

  Journal of parasitology research 20120101

• Epigallocatechin-3-gallate has an anti-platelet effect in a cyclic AMP-dependent manner.

  Journal of atherosclerosis and thrombosis 20120101

• Spherical lactic acid bacteria activate plasmacytoid dendritic cells immunomodulatory function via TLR9-dependent crosstalk with myeloid dendritic cells.

  PloS one 20120101

• Functional characterization of EngA(MS), a P-loop GTPase of Mycobacterium smegmatis.

  PloS one 20120101

• Heme oxygenase-1 induction and organic nitrate therapy: beneficial effects on endothelial dysfunction, nitrate tolerance, and vascular oxidative stress.

  International journal of hypertension 20120101

• Gasotransmitters: novel regulators of epithelial na(+) transport?

  Frontiers in physiology 20120101

• Complexity of the Mycoplasma fermentans M64 genome and metabolic essentiality and diversity among mycoplasmas.

  PloS one 20120101

• The essential role of AMPA receptor GluR2 subunit RNA editing in the normal and diseased brain.

  Frontiers in molecular neuroscience 20120101

• Identification and characterization of two novel RNA editing sites in grin1b transcripts of embryonic Danio rerio.

  Neural plasticity 20120101

• Alternative Mechanisms to Initiate Translation in Eukaryotic mRNAs.

  Comparative and functional genomics 20120101

• A novel k-mer mixture logistic regression for methylation susceptibility modeling of CpG dinucleotides in human gene promoters.

  BMC bioinformatics 20120101

• Role of neural NO synthase (nNOS) uncoupling in the dysfunctional nitrergic vasorelaxation of penile arteries from insulin-resistant obese Zucker rats.

  PloS one 20120101

• Structure of an enzyme-derived phosphoprotein recognition domain.

  PloS one 20120101

• Whole cell biosynthesis of a functional oligosaccharide, 2'-fucosyllactose, using engineered Escherichia coli.

  Microbial cell factories 20120101

• Disrupting the Acyl Carrier Protein/SpoT interaction in vivo: identification of ACP residues involved in the interaction and consequence on growth.

  PloS one 20120101

• Risk factors for persistent pulmonary hypertension of the newborn.

  Pulmonary circulation 20120101

• Kaposi's Sarcoma-Associated Herpesvirus microRNAs.

  Frontiers in microbiology 20120101

• Comparative genomics reveals adaptation by Alteromonas sp. SN2 to marine tidal-flat conditions: cold tolerance and aromatic hydrocarbon metabolism.

  PloS one 20120101

• Down-regulation of GABA(A) receptor via promiscuity with the vasoactive peptide urotensin II receptor. Potential involvement in astrocyte plasticity.

  PloS one 20120101

• Type I interferons as ambiguous modulators of chronic inflammation in the central nervous system.

  Frontiers in immunology 20120101

• Time dependent neuroprotection of mycophenolate mofetil: effects on temporal dynamics in glial proliferation, apoptosis, and scar formation.

  Journal of neuroinflammation 20120101

• Regulation of the proteasome by AMPK in endothelial cells: the role of O-GlcNAc transferase (OGT).

  PloS one 20120101

• Endothelial dysfunction and diabetes: effects on angiogenesis, vascular remodeling, and wound healing.

  International journal of vascular medicine 20120101

• Electrochemical detection of individual single nucleotide polymorphisms using monobase-modified apoferritin-encapsulated nanoparticles.

  Biosensors & bioelectronics 20120101

• Low affinity GPCRs for metabolic intermediates: challenges for pharmacologists.

  Frontiers in endocrinology 20120101

• Hepatoprotective Effects of Panus giganteus (Berk.) Corner against Thioacetamide- (TAA-) Induced Liver Injury in Rats.

  Evidence-based complementary and alternative medicine : eCAM 20120101

• Back to basics: pitting edema and the optimization of hypertension treatment in incident peritoneal dialysis patients (BRAZPD).

  PloS one 20120101

• M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection.

  PloS one 20120101

• NF-κB repression by PIAS3 mediated RelA SUMOylation.

  PloS one 20120101

• Chemical constituents and biological activities of the genus Subergorgia.

  Pharmacognosy reviews 20120101

• The evolving landscape of neurotoxicity by unconjugated bilirubin: role of glial cells and inflammation.

  Frontiers in pharmacology 20120101

• Targeting tumor perfusion and oxygenation to improve the outcome of anticancer therapy.

  Frontiers in pharmacology 20120101

• Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism.

  PloS one 20120101

• Down-regulation of GEP100 causes increase in E-cadherin levels and inhibits pancreatic cancer cell invasion.

  PloS one 20120101

• Radiolabeled nucleosides for predicting and monitoring the cancer therapeutic efficacy of chemodrugs.

  Current medicinal chemistry 20120101

• Interplay between HIV-1 and Host Genetic Variation: A Snapshot into Its Impact on AIDS and Therapy Response.

  Advances in virology 20120101

• Studies on the restriction of murine leukemia viruses by mouse APOBEC3.

  PloS one 20120101

• Explicit hypoxia targeting with tumor suppression by creating an 'obligate' anaerobic Salmonella Typhimurium strain.

  Scientific reports 20120101

• Thrombospondin-1 in early flow-related remodeling of mesenteric arteries from young normotensive and spontaneously hypertensive rats.

  The open cardiovascular medicine journal 20120101

• The 3' splice site of influenza A segment 7 mRNA can exist in two conformations: a pseudoknot and a hairpin.

  PloS one 20120101

• The G protein coupled receptor 3 is involved in cAMP and cGMP signaling and maintenance of meiotic arrest in porcine oocytes.

  PloS one 20120101

• Evidence for a functional adrenomedullin signaling pathway in the mouse retina.

  Molecular vision 20120101

• Maternal diet modulates placenta growth and gene expression in a mouse model of diabetic pregnancy.

  PloS one 20120101

• Efficiency of purine utilization by Helicobacter pylori: roles for adenosine deaminase and a NupC homolog.

  PloS one 20120101

• Progression from Sustained BK Viruria to Sustained BK Viremia with Immunosuppression Reduction Is Not Associated with Changes in the Noncoding Control Region of the BK Virus Genome.

  Journal of transplantation 20120101

• Voltammetric investigation of DNA damage induced by nitrofurazone and short-lived nitro-radicals with the use of an electrochemical DNA biosensor.

  Biosensors & bioelectronics 20120101

• The Bin3 RNA methyltransferase targets 7SK RNA to control transcription and translation.

  Wiley interdisciplinary reviews. RNA 20120101

• Remyelination induced by a DNA aptamer in a mouse model of multiple sclerosis.

  PloS one 20120101

• Analysis of 5'-mononucleotides in infant formula and adult/pediatric nutritional formula by liquid chromatography: First Action 2011.20.

  Journal of AOAC International 20120101

• HILIC-MS/MS method for the quantitation of nucleotides in infant formula and adult nutritional formula: First Action 2011.21.

  Journal of AOAC International 20120101

• Presynaptic selectivity of a ligand for serotonin 1A receptors revealed by in vivo PET assays of rat brain.

  PloS one 20120101

• Associations between purine metabolites and clinical symptoms in schizophrenia.

  PloS one 20120101

• Targeting phosphodiesterases in anti-platelet therapy.

  Handbook of experimental pharmacology 20120101

• Quantitative and chemical fingerprint analysis for the quality evaluation of Isatis indigotica based on ultra-performance liquid chromatography with photodiode array detector combined with chemometric methods.

  International journal of molecular sciences 20120101

• Enzymatically active and inactive phosphodiesterases and diguanylate cyclases are involved in regulation of Motility or sessility in Escherichia coli CFT073.

  mBio 20120101

• 2-Methylwyosine, a nucleoside with restricted anti conformation in the east region enforced by nucleobase moiety modification: synthesis and conformational analysis by NMR and molecular dynamics.

  Nucleosides, nucleotides & nucleic acids 20120101

• A possible explanation for anemia in patients treated with mycophenolic acid.

  Transplantation 20111227

• The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types.

  Chemistry & biology 20111223

• Phosphorodiamidates as a promising new phosphate prodrug motif for antiviral drug discovery: application to anti-HCV agents.

  Journal of medicinal chemistry 20111222

• XPD and hOGG1 gene polymorphisms in reperfusion oxidative stress.

  Genetics and molecular research : GMR 20111219

• Development and in vitro characterization of a novel bifunctional μ-agonist/δ-antagonist opioid tetrapeptide.

  ACS chemical biology 20111216

• C(5) modified uracil derivatives showing antiproliferative and erythroid differentiation inducing activities on human chronic myelogenous leukemia K562 cells.

  European journal of pharmacology 20111215

• CCR2 receptor antagonists: optimization of biaryl sulfonamides to increase activity in whole blood.

  Bioorganic & medicinal chemistry letters 20111215

• Identifying guanosine self assembly at natural isotopic abundance by high-resolution 1H and 13C solid-state NMR spectroscopy.

  Journal of the American Chemical Society 20111214

• Pyruvate is the source of the two carbons that are required for formation of the imidazoline ring of 4-demethylwyosine.

  Biochemistry 20111213

• Discovery of aminobenzyloxyarylamides as κ opioid receptor selective antagonists: application to preclinical development of a κ opioid receptor antagonist receptor occupancy tracer.

  Journal of medicinal chemistry 20111208

• Involvement of NOX1/NADPH oxidase in morphine-induced analgesia and tolerance.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20111207

• DNA-catalyzed reductive amination.

  Angewandte Chemie (International ed. in English) 20111202

• Design, synthesis and characterisation of guanosine-based amphiphiles.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20111202

• Role of gonadal hormones on mu-opioid-stimulated [³⁵S]GTPγS binding and morphine-mediated antinociception in male and female Sprague-Dawley rats.

  Psychopharmacology 20111201

• Effect of high pressure processing on the level of some purines and pyrimidines nucleosides and bases in dry cured and cooked ham.

  Meat science 20111201

• Possible biological markers of the time of processing of dry-cured ham.

  Meat science 20111201

• Conformational preferences of modified nucleoside N(2)-methylguanosine (m(2)G) and its derivative N(2), N(2)-dimethylguanosine (m(2)(2)G) occur at 26th position (hinge region) in tRNA.

  Cell biochemistry and biophysics 20111201

• Identification of the core sequence elements in Penaeus stylirostris densovirus promoters.

  Virus genes 20111201

• tRNA structural and functional changes induced by oxidative stress.

  Cellular and molecular life sciences : CMLS 20111201

• Effect of ΔFosB overexpression on opioid and cannabinoid receptor-mediated signaling in the nucleus accumbens.

  Neuropharmacology 20111201

• The 8-hydroxydeoxyguanosine concentrations according to hormone therapy and S326C polymorphism of OGG1 gene in postmenopausal women.

  Molecular genetics and metabolism 20111201

• Essential role for orbitofrontal serotonin 1B receptors in obsessive-compulsive disorder-like behavior and serotonin reuptake inhibitor response in mice.

  Biological psychiatry 20111201

• Urinary markers of nucleic acid oxidation and long-term mortality of newly diagnosed type 2 diabetic patients.

  Diabetes care 20111201

• Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein.

  Nature neuroscience 20111201

• Asymmetry of (13)C labeled 3-pyruvate affords improved site specific labeling of RNA for NMR spectroscopy.

  Journal of biomolecular NMR 20111201

• Purine nucleoside phosphorylase deficiency: a mutation update.

  Nucleosides, nucleotides & nucleic acids 20111201

• Overexpression of dedicator of cytokinesis I (Dock180) in ovarian cancer correlated with aggressive phenotype and poor patient survival.

  Histopathology 20111201

• Glut1 deficiency syndrome and erythrocyte glucose uptake assay.

  Annals of neurology 20111201

• Dual or triple activation of TLR7, TLR8, and/or TLR9 by single-stranded oligoribonucleotides.

  Nucleic acid therapeutics 20111201

• The RNA silencing enzyme RNA polymerase v is required for plant immunity.

  PLoS genetics 20111201

• Treatment of myasthenia gravis based on its immunopathogenesis.

  Journal of clinical neurology (Seoul, Korea) 20111201

• Anti-adipogenic activity of Cordyceps militaris in 3T3-L1 cells.

  Natural product communications 20111201

• The Protective Effect of Black Ginseng Against Transient Focal Ischemia-induced Neuronal Damage in Rats.

  The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20111201

• Treatment of recalcitrant herpes simplex virus with topical imiquimod.

  Cutis 20111201

• [Study on HPLC fingerprint chromatograms of Arisaematis Rhizoma].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111201

• cGMP Signaling, Phosphodiesterases and Major Depressive Disorder.

  Current neuropharmacology 20111201

• A novel form of low-frequency hippocampal mossy fiber plasticity induced by bimodal mGlu1 receptor signaling.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20111123

• A metabolic profiling analysis of symptomatic gout in human serum and urine using high performance liquid chromatography-diode array detector technique.

  Clinica chimica acta; international journal of clinical chemistry 20111120

• RAM/Fam103a1 is required for mRNA cap methylation.

  Molecular cell 20111118

• An active-site guanine participates in glmS ribozyme catalysis in its protonated state.

  Journal of the American Chemical Society 20111116

• Solution structure of the state 1 conformer of GTP-bound H-Ras protein and distinct dynamic properties between the state 1 and state 2 conformers.

  The Journal of biological chemistry 20111111

• Synthesis of 2'-N-methylamino-2'-deoxyguanosine and 2'-N,N-dimethylamino-2'-deoxyguanosine and their incorporation into RNA by phosphoramidite chemistry.

  The Journal of organic chemistry 20111104

• Modulation of GABA transport by adenosine A1R-A2AR heteromers, which are coupled to both Gs- and G(i/o)-proteins.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20111102

• Sequential and opposing alterations of 5-HT(1A) receptor function during withdrawal from chronic morphine.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20111101

• Retron Se72 utilizes a unique strategy of the self-priming initiation of reverse transcription.

  Cellular and molecular life sciences : CMLS 20111101

• Recombinant WNTs differentially activate β-catenin-dependent and -independent signalling in mouse microglia-like cells.

  Acta physiologica (Oxford, England) 20111101

• Protein therapy using heme-oxygenase-1 fused to a polyarginine transduction domain attenuates cerebral vasospasm after experimental subarachnoid hemorrhage.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20111101

• Transactivation of epidermal growth factor receptor by enhanced levels of endogenous angiotensin II contributes to the overexpression of Giα proteins in vascular smooth muscle cells from SHR.

  Cellular signalling 20111101

• Adenosine-to-inosine RNA editing meets cancer.

  Carcinogenesis 20111101

• The clozapine metabolite N-desmethylclozapine displays variable activity in diverse functional assays at human dopamine D₂ and serotonin 5-HT₁A receptors.

  European journal of pharmacology 20111101

• Sex difference in κ-opioid receptor (KOPR)-mediated behaviors, brain region KOPR level and KOPR-mediated guanosine 5'-O-(3-[35S]thiotriphosphate) binding in the guinea pig.

  The Journal of pharmacology and experimental therapeutics 20111101

• Differential effects of nociceptin/orphanin FQ (NOP) receptor agonists in acute versus chronic pain: studies with bifunctional NOP/μ receptor agonists in the sciatic nerve ligation chronic pain model in mice.

  The Journal of pharmacology and experimental therapeutics 20111101

• Pre-ovulatory LH/hCG surge decreases C-type natriuretic peptide secretion by ovarian granulosa cells to promote meiotic resumption of pre-ovulatory oocytes.

  Human reproduction (Oxford, England) 20111101

• Stability and mismatch discrimination of locked nucleic acid-DNA duplexes.

  Biochemistry 20111101

• A prophylactic effect of an oligodeoxynucleotide containing a cytidine-guanosine motif against Japanese cedar pollen-induced T-helper type 2 allergic response.

  The Journal of asthma : official journal of the Association for the Care of Asthma 20111101

• Evidence for macrocyclic lactone anthelmintic resistance in Dirofilaria immitis.

  Topics in companion animal medicine 20111101

• Simultaneous determination of five nucleosides and nucleobases of Rehmannia glutinosa Libosch. by high performance liquid chromatography.

  Yao xue xue bao = Acta pharmaceutica Sinica 20111101

• STING is a direct innate immune sensor of cyclic di-GMP.

  Nature 20111027

• 8-(p-CF3-cinnamyl)-modified purine nucleosides as promising fluorescent probes.

  Organic & biomolecular chemistry 20111026

• Pin1 and WWP2 regulate GluR2 Q/R site RNA editing by ADAR2 with opposing effects.

  The EMBO journal 20111019

• Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity.

  The EMBO journal 20111019

• Towards multimodal HPLC separations on humic acid-bonded aminopropyl silica: RPLC and LEC behavior.

  Talanta 20111015

• GTP-dependent binding and nuclear transport of RNA polymerase II by Npa3 protein.

  The Journal of biological chemistry 20111014

• Protein glycoengineering enabled by the versatile synthesis of aminooxy glycans and the genetically encoded aldehyde tag.

  Journal of the American Chemical Society 20111012

• Structure-function analysis from the outside in: long-range tertiary contacts in RNA exhibit distinct catalytic roles.

  Biochemistry 20111011

• Molecular targeting of CSN5 in human hepatocellular carcinoma: a mechanism of therapeutic response.

  Oncogene 20111006

• Synthesis of 2'-deoxy-2'-[18F]fluoro-9-β-D-arabinofuranosylguanine: a novel agent for imaging T-cell activation with PET.

  Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20111001

• The state-of-the-art determination of urinary nucleosides using chromatographic techniques 'hyphenated' with advanced bioinformatic methods.

  Analytical and bioanalytical chemistry 20111001

• G-quadruplexes: from guanine gels to chemotherapeutics.

  Molecular biotechnology 20111001

• Guanosine supplementation reduces the antiproliferative and apoptotic effects of the IMPDH inhibitor gnidilatimonoein in K562 cells.

  Cell biology international 20111001

• Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy.

  Cancer 20111001

• Anti-platelet therapy: phosphodiesterase inhibitors.

  British journal of clinical pharmacology 20111001

• Zinc homeostasis and signaling in health and diseases: Zinc signaling.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20111001

• Potentiation of μ-opioid receptor-mediated signaling by ketamine.

  Journal of neurochemistry 20111001

• Regulation of ingestive behaviors in the rat by GSK1521498, a novel micro-opioid receptor-selective inverse agonist.

  The Journal of pharmacology and experimental therapeutics 20111001

• Physiological response to membrane protein overexpression in E. coli.

  Molecular & cellular proteomics : MCP 20111001

• Molecular determinants of PKA-dependent inhibition of TRPC5 channel.

  American journal of physiology. Cell physiology 20111001

• Triplet-state dynamics of a metalloporphyrin photosensitiser (PtTMPyP4) in the presence of halides and purine mononucleotides.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20111001

• The G protein-coupled cannabinoid-1 (CB1) receptor of mammalian brain: inhibition by phthalate esters in vitro.

  Neurochemistry international 20111001

• Differential stringent control of Escherichia coli rRNA promoters: effects of ppGpp, DksA and the initiating nucleotides.

  Microbiology (Reading, England) 20111001

• Neutral loss and precursor ion scan tandem mass spectrometry for study of activated benzopyrene-DNA adducts.

  Analytical and bioanalytical chemistry 20111001

• Substrate-induced conformational changes in Plasmodium falciparum guanosine monophosphate synthetase.

  The FEBS journal 20111001

• CART peptide stimulation of G protein-mediated signaling in differentiated PC12 cells: identification of PACAP 6-38 as a CART receptor antagonist.

  Neuropeptides 20111001

• Pharmacological mechanisms underlying the antinociceptive and tolerance effects of the 6,14-bridged oripavine compound 030418.

  Acta pharmacologica Sinica 20111001

• Probing DNA interstrand cross-link formation by an oxidized abasic site using nonnative nucleotides.

  Bioorganic & medicinal chemistry 20111001

• The herpes simplex virus-1 transactivator infected cell protein-4 drives VEGF-A dependent neovascularization.

  PLoS pathogens 20111001

• Sustained CD8+ T cell memory inflation after infection with a single-cycle cytomegalovirus.

  PLoS pathogens 20111001

• Identification of widespread ultra-edited human RNAs.

  PLoS genetics 20111001

• Mycophenolic acid mediated mitochondrial membrane potential transition change lead to T lymphocyte apoptosis.

  Journal of the Korean Surgical Society 20111001

• Identification of the orphan G protein-coupled receptor GPR31 as a receptor for 12-(S)-hydroxyeicosatetraenoic acid.

  The Journal of biological chemistry 20110930

• A quantitative study of neuronal nitric oxide synthase expression in laminae I-III of the rat spinal dorsal horn.

  Neuroscience 20110929

• Identification of ML204, a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.

  The Journal of biological chemistry 20110923

• Alkylating potential of α,β-unsaturated compounds.

  Organic & biomolecular chemistry 20110921

• Circular dichroism and UV-Vis absorption spectroscopic monitoring of production of chiral silver nanoparticles templated by guanosine 5'-monophosphate.

  The Analyst 20110921

• A prebiotic role for 8-oxoguanosine as a flavin mimic in pyrimidine dimer photorepair.

  Journal of the American Chemical Society 20110921

• Nucleobase transport by human equilibrative nucleoside transporter 1 (hENT1).

  The Journal of biological chemistry 20110916

• Role for the membrane receptor guanylyl cyclase-C in attention deficiency and hyperactive behavior.

  Science (New York, N.Y.) 20110916

• Guanine-induced inhibition of renal Na(+)-ATPase activity: evidence for the involvement of the Gi protein-coupled receptor.

  Archives of biochemistry and biophysics 20110915

• Identification and quantification of nucleosides and nucleobases in Geosaurus and Leech by hydrophilic-interaction chromatography.

  Talanta 20110915

• Activation and inhibition of CTP synthase from Trypanosoma brucei, the causative agent of African sleeping sickness.

  Bioorganic & medicinal chemistry letters 20110915

• Ebola virus entry requires the cholesterol transporter Niemann-Pick C1.

  Nature 20110915

• Adjuvant effect of cationic liposomes and CpG depends on administration route.

  Journal of controlled release : official journal of the Controlled Release Society 20110905

• Effect of thioethers on DNA platination by trans-platinum complexes.

  Inorganic chemistry 20110905

• Administration route and carrier dependent effects on vaccine efficacy: implications for vaccine design.

  Journal of controlled release : official journal of the Controlled Release Society 20110905

• Identification of a novel Arabidopsis thaliana nitric oxide-binding molecule with guanylate cyclase activity in vitro.

  FEBS letters 20110902

• Genome-wide evaluation and discovery of vertebrate A-to-I RNA editing sites.

  Biochemical and biophysical research communications 20110902

• Nitric oxide signaling modulates synaptic transmission during early postnatal development.

  Cerebral cortex (New York, N.Y. : 1991) 20110901

• Dietary fish oil reduces DNA adduct formation while estradiol upregulates apoptosis in response to DNA damage in the rat colon.

  Digestive diseases and sciences 20110901

• Functional coupling between metabotropic glutamate receptors and G-proteins in rat cerebral cortex assessed by guanosine-5'-O-(3-[(35)S]thio)triphosphate binding assay.

  Basic & clinical pharmacology & toxicology 20110901

• Natriuretic peptide receptor-3 underpins the disparate regulation of endothelial and vascular smooth muscle cell proliferation by C-type natriuretic peptide.

  British journal of pharmacology 20110901

• ER-resident Gi2 protein controls sar1 translocation onto the ER during budding of transport vesicles.

  Journal of cellular biochemistry 20110901

• A dual acting compound releasing nitric oxide (NO) and ibuprofen, NCX 320, shows significant therapeutic effects in a mouse model of muscular dystrophy.

  Pharmacological research 20110901

• Characterization of a sphingosine 1-phosphate receptor antagonist prodrug.

  The Journal of pharmacology and experimental therapeutics 20110901

• Third intracellular loop of glucagon like-peptide-1 receptor is coupled with endogenous mono-ADP-ribosyltransferase - novel type of receptor regulation?

  European journal of pharmacology 20110901

• Estrogen regulation of the dopamine-activated GIRK channel in pituitary lactotrophs: implications for regulation of prolactin release during the estrous cycle.

  American journal of physiology. Regulatory, integrative and comparative physiology 20110901

• Neuroprotective effect of guanosine against glutamate-induced cell death in rat hippocampal slices is mediated by the phosphatidylinositol-3 kinase/Akt/ glycogen synthase kinase 3β pathway activation and inducible nitric oxide synthase inhibition.

  Journal of neuroscience research 20110901

• Validation of the catalytic mechanism of Escherichia coli purine nucleoside phosphorylase by structural and kinetic studies.

  Biochimie 20110901

• ppGpp in Sinorhizobium meliloti: biosynthesis in response to sudden nutritional downshifts and modulation of the transcriptome.

  Molecular microbiology 20110901

• Emerging drugs for varicella-zoster virus infections.

  Expert opinion on emerging drugs 20110901

• Mutagenicity of secondary oxidation products of 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate (8-hydroxy-2'- deoxyguanosine 5'-triphosphate).

  Mutation research 20110901

• RIC8 is a guanine-nucleotide exchange factor for Galpha subunits that regulates growth and development in Neurospora crassa.

  Genetics 20110901

• Cyclic GMP induced apoptosis via protein kinase G in oestrogen receptor-positive and -negative breast cancer cell lines.

  The FEBS journal 20110901

• Signalling by the global regulatory molecule ppGpp in bacteria and chloroplasts of land plants.

  Plant biology (Stuttgart, Germany) 20110901

• Transfer RNA-mediated regulation of ribosome dynamics during protein synthesis.

  Nature structural & molecular biology 20110901

• 6-Thioguanine inhibition of parathyroid hormone-related protein expression is mediated by GLI2.

  Anticancer research 20110901

• Influence of nitric oxide on in vitro growth, survival, steroidogenesis, and apoptosis of follicle stimulating hormone stimulated buffalo (Bubalus bubalis) preantral follicles.

  Journal of veterinary science 20110901

• BrabA.11339.a: anomalous diffraction and ligand binding guide towards the elucidation of the function of a 'putative β-lactamase-like protein' from Brucella melitensis.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20110901

• Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by trypanolytic factor 1.

  PLoS neglected tropical diseases 20110901

• [Effects of mycophenolic acid on human bone marrow-derived mesenchymal stem cells in vitro].

  Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20110901

• Mechanisms and factors that influence high frequency retroviral recombination.

  Viruses 20110901

• Recombination in eukaryotic single stranded DNA viruses.

  Viruses 20110901

• Neuropsychiatric systemic lupus erythematosus.

  Current neuropharmacology 20110901

• Antioxidative caffeoylquinic acids and flavonoids from Hemerocallis fulva flowers.

  Journal of agricultural and food chemistry 20110824

• Stereoselective synthesis of amides sharing the guanosine 5'-monophosphate scaffold and Umami enhancement studies using human sensory and hT1R1/rT1R3 receptor assays.

  Journal of agricultural and food chemistry 20110824

• Synthesis and assembling properties of bioorganometallic cyclometalated Au(III) alkynyls bearing guanosine moieties.

  Organic & biomolecular chemistry 20110821

• Ligand modulation of the Epstein-Barr virus-induced seven-transmembrane receptor EBI2: identification of a potent and efficacious inverse agonist.

  The Journal of biological chemistry 20110819

• Systemic administration of guanosine promotes functional and histological improvement following an ischemic stroke in rats.

  Brain research 20110817

• Chronic neuropathic pain in mice reduces μ-opioid receptor-mediated G-protein activity in the thalamus.

  Brain research 20110811

• shRNA knockdown of guanylate cyclase 2e or cyclic nucleotide gated channel alpha 1 increases photoreceptor survival in a cGMP phosphodiesterase mouse model of retinitis pigmentosa.

  Journal of cellular and molecular medicine 20110801

• Progesterone signals through membrane progesterone receptors (mPRs) in MDA-MB-468 and mPR-transfected MDA-MB-231 breast cancer cells which lack full-length and N-terminally truncated isoforms of the nuclear progesterone receptor.

  Steroids 20110801

• Absolute configurations and stability of cyclic guanosine mono-adducts with glyoxal and methylglyoxal.

  Chirality 20110801

• Internalization of exogenous ADP-ribosylation factor 6 (Arf6) proteins into cells.

  Molecular and cellular biochemistry 20110801

• Curcumin mediates both dilation and constriction of peripheral arterioles via adrenergic receptors.

  The Journal of investigative dermatology 20110801

• Agonist-induced desensitization/resensitization of human G protein-coupled receptor 17: a functional cross-talk between purinergic and cysteinyl-leukotriene ligands.

  The Journal of pharmacology and experimental therapeutics 20110801

• Enhanced production of GDP-L-fucose by overexpression of NADPH regenerator in recombinant Escherichia coli.

  Applied microbiology and biotechnology 20110801

• Understanding the effect of different assay formats on agonist parameters: a study using the µ-opioid receptor.

  Journal of biomolecular screening 20110801

• High-throughput fluorescence polarization assay for the enzymatic activity of GTPase-activating protein of ADP-ribosylation factor (ARFGAP).

  Journal of biomolecular screening 20110801

• Depletion of GTP pool is not the predominant mechanism by which ribavirin exerts its antiviral effect on Lassa virus.

  Antiviral research 20110801

• Site-specific recognition of guanosine by manganese(III) corroles in DNA non-duplex regions through active oxygen transfer.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20110801

• Sensitization to MDMA locomotor effects and changes in the functionality of 5-HT(2A) and D₂ receptors in mice.

  Behavioural pharmacology 20110801

• Quantification of cAMP and cGMP analogs in intact cells: pitfalls in enzyme immunoassays for cyclic nucleotides.

  Naunyn-Schmiedeberg's archives of pharmacology 20110801

• Enzyme kinetics of the mitochondrial deoxyribonucleoside salvage pathway are not sufficient to support rapid mtDNA replication.

  PLoS computational biology 20110801

• Epigenetic abnormalities in myeloproliferative neoplasms: a target for novel therapeutic strategies.

  Clinical epigenetics 20110801

• Benchmarking AMBER force fields for RNA: comparisons to NMR spectra for single-stranded r(GACC) are improved by revised χ torsions.

  The journal of physical chemistry. B 20110728

• Cell-type-specific CCK2 receptor signaling underlies the cholecystokinin-mediated selective excitation of hippocampal parvalbumin-positive fast-spiking basket cells.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20110727

• Conformational states of ADP ribosylation factor 1 complexed with different guanosine triphosphates as studied by 31P NMR spectroscopy.

  Biochemistry 20110726

• Hydrogen-bond-directed giant unilamellar vesicles of guanosine derivative: preparation, properties, and fusion.

  Langmuir : the ACS journal of surfaces and colloids 20110719

• The clinical potential of the acyclic (and cyclic) nucleoside phosphonates: the magic of the phosphonate bond.

  Biochemical pharmacology 20110715

• Activation of κ opioid receptors increases intrinsic excitability of dentate gyrus granule cells.

  The Journal of physiology 20110715

• The melatonergic agonist and clinically active antidepressant, agomelatine, is a neutral antagonist at 5-HT(2C) receptors.

  The international journal of neuropsychopharmacology 20110701

• Influence of irradiation on in vitro red-blood-cell (RBC) storage variables of leucoreduced RBCs in additive solution PAGGS-M.

  Vox sanguinis 20110701

• cGMP-dependent ABA-induced stomatal closure in the ABA-insensitive Arabidopsis mutant abi1-1.

  The New phytologist 20110701

• Measuring thermodynamic details of DNA hybridization using fluorescence.

  Biopolymers 20110701

• Role of SRC family kinase in extracellular renal cyclic guanosine 3',5'-monophosphate- and pressure-induced natriuresis.

  Hypertension (Dallas, Tex. : 1979) 20110701

• A three-dimensional pharmacophore model for IMPDH inhibitors.

  Chemical biology & drug design 20110701

• Multiple roles for Plasmodium berghei phosphoinositide-specific phospholipase C in regulating gametocyte activation and differentiation.

  Cellular microbiology 20110701

• The bulky N6 substituent of cabergoline is responsible for agonism of this drug at 5-hydroxytryptamine 5-HT2A and 5-HT2B receptors and thus is a determinant of valvular heart disease.

  The Journal of pharmacology and experimental therapeutics 20110701

• A selective adenosine sensor derived from a triplex DNA aptamer.

  Analytical and bioanalytical chemistry 20110701

• The L-kynurenine signalling pathway in trigeminal pain processing: a potential therapeutic target in migraine?

  Cephalalgia : an international journal of headache 20110701

• Arabidopsis thaliana nucleosidase mutants provide new insights into nucleoside degradation.

  The New phytologist 20110701

• Study of retention behaviour and mass spectrometry compatibility in zwitterionic hydrophilic interaction chromatography for the separation of modified nucleosides and nucleobases.

  Journal of chromatography. A 20110701

• Oxidative damage in multiple sclerosis lesions.

  Brain : a journal of neurology 20110701

• Paradoxical facilitation of exocytosis by inhibition of L-type calcium channels of bovine chromaffin cells.

  Biochemical and biophysical research communications 20110701

• Synaptic transmission from horizontal cells to cones is impaired by loss of connexin hemichannels.

  PLoS biology 20110701

• Complete genome sequence of Treponema succinifaciens type strain (6091).

  Standards in genomic sciences 20110701

• [Characterization of the Rela/SpoT homologue slr1325 (syn-rsh) of the cyanobacterium Synechocystis sp. PCC6803].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20110701

• Selective activation of Akt1 by mammalian target of rapamycin complex 2 regulates cancer cell migration, invasion, and metastasis.

  Oncogene 20110630

• Nucleobase and ribose modifications control immunostimulation by a microRNA-122-mimetic RNA.

  Journal of the American Chemical Society 20110622

• The design and use of a simple System Suitability Test Mix for generic reverse phase high performance liquid chromatography-mass spectrometry systems and the implications for automated system monitoring using global software tracking.

  Journal of chromatography. A 20110610

• Calpain chronicle--an enzyme family under multidisciplinary characterization.

  Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110610

• Metabolomic analysis characterizes tissue specific indomethacin-induced metabolic perturbations of rats.

  The Analyst 20110607

• Evidence for the existence of a specific g protein-coupled receptor activated by guanosine.

  ChemMedChem 20110606

• Ric-8B is a GTP-dependent G protein alphas guanine nucleotide exchange factor.

  The Journal of biological chemistry 20110603

• Guanosine is neuroprotective against oxygen/glucose deprivation in hippocampal slices via large conductance Ca²+-activated K+ channels, phosphatidilinositol-3 kinase/protein kinase B pathway activation and glutamate uptake.

  Neuroscience 20110602

• Protein cysteine S-guanylation and electrophilic signal transduction by endogenous nitro-nucleotides.

  Amino acids 20110601

• Quantification of hormone sensitive lipase phosphorylation and colocalization with lipid droplets in murine 3T3L1 and human subcutaneous adipocytes via automated digital microscopy and high-content analysis.

  Assay and drug development technologies 20110601

• Contribution of Rho-kinase to membrane excitability of murine colonic smooth muscle.

  British journal of pharmacology 20110601

• Synthesis of GDP-mannose using coupling fermentation of recombinant Escherichia coli.

  Biotechnology letters 20110601

• Genetic ablation of delta opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes opioid analgesia.

  Pain 20110601

• Genetic and environmental influences on oxidative damage assessed in elderly Danish twins.

  Free radical biology & medicine 20110601

• Genetic polymorphisms of the beta2-adrenergic receptor relate to guanosine protein-coupled stimulator receptor dysfunction in fibromyalgia syndrome.

  The Journal of rheumatology 20110601

• Role of the all1549 (ana-rsh) gene, a relA/spoT homolog, of the Cyanobacterium Anabaena sp. PCC7120.

  Current microbiology 20110601

• The dksA promoter is negatively feedback regulated by DksA and ppGpp.

  Molecular microbiology 20110601

• Ras signaling pathways mediate NGF-induced enhancement of excitability of small-diameter capsaicin-sensitive sensory neurons from wildtype but not Nf1+/- mice.

  Neuroscience letters 20110601

• Activation of cryptic aminoglycoside resistance in Salmonella enterica.

  Molecular microbiology 20110601

• Ocular neuroprotection by siRNA targeting caspase-2.

  Cell death & disease 20110601

• Chiral selectivity of guanosine media in capillary electrophoresis.

  Electrophoresis 20110601

• The N-terminus of the RNA polymerase from infectious pancreatic necrosis virus is the determinant of genome attachment.

  PLoS pathogens 20110601

• Biochemical aspects of nitric oxide synthase feedback regulation by nitric oxide.

  Interdisciplinary toxicology 20110601

• Retinitis pigmentosa: genes and disease mechanisms.

  Current genomics 20110601

• Free energy simulations of a GTPase: GTP and GDP binding to archaeal initiation factor 2.

  The journal of physical chemistry. B 20110526

• Tightening of active site interactions en route to the transition state revealed by single-atom substitution in the guanosine-binding site of the Tetrahymena group I ribozyme.

  Journal of the American Chemical Society 20110525

• Ultrafast photoinduced electron transfer between tetramethylrhodamine and guanosine in aqueous solution.

  The journal of physical chemistry. B 20110519

• Circular dichroism study of supramolecular assemblies of guanosine 5'-monophosphate.

  The journal of physical chemistry. B 20110519

• Strand invasion of mixed-sequence, double-helical B-DNA by γ-peptide nucleic acids containing G-clamp nucleobases under physiological conditions.

  Biochemistry 20110517

• Extracellular nucleotide derivatives protect cardiomyocytes against hypoxic stress.

  Biochemical pharmacology 20110515

• Chirality delivery from a chiral copper(II) nucleotide complex molecule to its supramolecular architecture.

  Dalton transactions (Cambridge, England : 2003) 20110514

• Dynamics and couplings of N-H stretching excitations of guanosine-cytidine base pairs in solution.

  The journal of physical chemistry. B 20110512

• Pin-point chemical modification of RNA with diverse molecules through the functionality transfer reaction and the copper-catalyzed azide-alkyne cycloaddition reaction.

  Chemical communications (Cambridge, England) 20110507

• Radical-based alkylation of guanine derivatives in aqueous medium.

  Organic & biomolecular chemistry 20110507

• Cloning and characterization of purine nucleoside phosphorylase in Escherichia coli and subsequent ribavirin biosynthesis using immobilized recombinant cells.

  Enzyme and microbial technology 20110506

• Photophysical properties of Atto655 dye in the presence of guanosine and tryptophan in aqueous solution.

  The journal of physical chemistry. B 20110505

• Dehydroascorbic acid adducts of guanosine residues: possible biological implications.

  Chembiochem : a European journal of chemical biology 20110502

• Intradermal cytosine-phosphate-guanosine treatment reduces lung inflammation but induces IFN-γ-mediated airway hyperreactivity in a murine model of natural rubber latex allergy.

  American journal of respiratory cell and molecular biology 20110501

• Molecular recognition of the antiretroviral drug abacavir: towards the development of a novel carbazole-based fluorosensor.

  Journal of fluorescence 20110501

• Mycophenolate mofetil impairs transduction of single-stranded adeno-associated viral vectors.

  Human gene therapy 20110501

• Long-term diabetic complications may be ameliorated by targeting Rho kinase.

  Diabetes/metabolism research and reviews 20110501

• Fluorescent and colorimetric chemosensors for detection of nucleotides, FAD and NADH: highlighted research during 2004-2010.

  Chemical Society reviews 20110501

• The selective sphingosine 1-phosphate receptor 1 agonist ponesimod protects against lymphocyte-mediated tissue inflammation.

  The Journal of pharmacology and experimental therapeutics 20110501

• Role of nucleoside transporters SLC28A2/3 and SLC29A1/2 genetics in ribavirin therapy: protection against anemia in patients with chronic hepatitis C.

  Pharmacogenetics and genomics 20110501

• Engineering and visualization of bacteria for targeting infarcted myocardium.

  Molecular therapy : the journal of the American Society of Gene Therapy 20110501

• Transient RNA-protein interactions in RNA folding.

  The FEBS journal 20110501

• The role of melatonin in the pathogenesis of adolescent idiopathic scoliosis (AIS).

  European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 20110501

• Life without the essential bacterial tRNA Ile2-lysidine synthetase TilS: a case of tRNA gene recruitment in Bacillus subtilis.

  Molecular microbiology 20110501

• The clinical efficacy of L-DOPA and STN-DBS share a common marker: reduced GABA content in the motor thalamus.

  Cell death & disease 20110501

• Incorporation of guanosine gels into sieving matrices for length- and sequence-based separation of DNA in capillary electrophoresis.

  Electrophoresis 20110501

• Identification of hammerhead ribozymes in all domains of life reveals novel structural variations.

  PLoS computational biology 20110501

• Predicting sites of ADAR editing in double-stranded RNA.

  Nature communications 20110501

• Involvement of BMPR2 in the protective effect of fluoxetine against monocrotaline-induced endothelial apoptosis in rats.

  Canadian journal of physiology and pharmacology 20110501

• Genetic reconstruction of protozoan rRNA decoding sites provides a rationale for paromomycin activity against Leishmania and Trypanosoma.

  PLoS neglected tropical diseases 20110501

• Transplantation of muscle-derived stem cells into the corpus cavernosum restores erectile function in a rat model of cavernous nerve injury.

  Korean journal of urology 20110501

• Base-selective adsorption of nucleosides to pore-engineered nanocarbon, carbon nanocage.

  Journal of nanoscience and nanotechnology 20110501

• Lactobacillus adhesion to mucus.

  Nutrients 20110501

• High expression of NPY receptors in the human testis.

  Molecular and cellular endocrinology 20110430

• Critical roles of interactions among switch I-preceding residues and between switch II and its neighboring alpha-helix in conformational dynamics of the GTP-bound Ras family small GTPases.

  The Journal of biological chemistry 20110429

• A G-octamer scaffold via self-assembly of a guanosine-based Au(I) isonitrile complex for Au(I)-Au(I) interaction.

  Chemical communications (Cambridge, England) 20110428

• 8-Oxoguanosine switches modulate the activity of alkylated siRNAs by controlling steric effects in the major versus minor grooves.

  Journal of the American Chemical Society 20110427

• Ammonia channeling in Plasmodium falciparum GMP synthetase: investigation by NMR spectroscopy and biochemical assays.

  Biochemistry 20110426

• Release of bioactive volatiles from supramolecular hydrogels: influence of reversible acylhydrazone formation on gel stability and volatile compound evaporation.

  Organic & biomolecular chemistry 20110421

• Dependence of RelA-mediated (p)ppGpp formation on tRNA identity.

  Biochemistry 20110419

• Carcinogenic heavy metals, As3+ and Cr6+, increase affinity of nuclear mono-ubiquitinated annexin A1 for DNA containing 8-oxo-guanosine, and promote translesion DNA synthesis.

  Toxicology and applied pharmacology 20110415

• Sildenafil reverses ABCB1- and ABCG2-mediated chemotherapeutic drug resistance.

  Cancer research 20110415

• Discovery of a potent and efficacious peptide derivative for δ/μ opioid agonist/neurokinin 1 antagonist activity with a 2',6'-dimethyl-L-tyrosine: in vitro, in vivo, and NMR-based structural studies.

  Journal of medicinal chemistry 20110414

• Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease.

  The Journal of biological chemistry 20110408

• Single atom modification leads to enhanced nucleotide self-assembly: the role of cation bridging.

  Chemical communications (Cambridge, England) 20110407

• Dynamical insight into Caenorhabditis elegans eIF4E recognition specificity for mono-and trimethylated structures of mRNA 5' cap.

  Journal of molecular modeling 20110401

• Proper laboratory notebook practices: protecting your intellectual property.

  Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20110401

• Molecular cloning and characterization of a novel ras-related protein (rap2) from Clonorchis sinensis.

  Parasitology research 20110401

• Nitrergic inhibition of tachykininergic neuro-muscular transmission via cyclic GMP in the hamster ileum.

  The Journal of veterinary medical science 20110401

• Pharmacological characterization of a nociceptin receptor from zebrafish (Danio rerio).

  Journal of molecular endocrinology 20110401

• The association between low-grade inflammation, iron status and nucleic acid oxidation in the elderly.

  Free radical research 20110401

• Mechanism of action of ribavirin in a novel hepatitis C virus replication cell system.

  Virus research 20110401

• Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.

  Diabetes 20110401

• DNA-methylation profiling distinguishes malignant melanomas from benign nevi.

  Pigment cell & melanoma research 20110401

• A guanosine 3',5'-cyclic monophosphate (cGMP) reporter system based on the G-kinase/CREB/CRE signal transduction pathway.

  Biochemical and biophysical research communications 20110401

• Simultaneous determination of 5'-monophosphate nucleotides in infant formulas by HPLC-MS.

  Journal of chromatographic science 20110401

• Profile of nucleotides and nucleosides in Taiwanese human milk.

  Pediatrics and neonatology 20110401

• Fluctuations in spo0A transcription control rare developmental transitions in Bacillus subtilis.

  PLoS genetics 20110401

• Changes in Adenosine Deaminase Activity in Patients with Type 2 Diabetes Mellitus and Effect of DPP-4 Inhibitor Treatment on ADA Activity.

  Diabetes & metabolism journal 20110401

• Excited-state dynamics in 6-thioguanosine from the femtosecond to microsecond time scale.

  The journal of physical chemistry. B 20110331

• In situ evaluation of anticancer drug methotrexate-DNA interaction using a DNA-electrochemical biosensor and AFM characterization.

  Physical chemistry chemical physics : PCCP 20110328

• Ganciclovir ophthalmic gel 0.15%: in acute herpetic keratitis (dendritic ulcers).

  Drugs 20110326

• Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3.

  The Journal of biological chemistry 20110325

• Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral.

  Virology 20110315

• Design, synthesis, pharmacological evaluation, and structure-activity study of novel endomorphin analogues with multiple structural modifications.

  Journal of medicinal chemistry 20110310

• The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.

  Nature communications 20110308

• Non-surgical stem cell delivery strategies and in vivo cell tracking to injured myocardium.

  The international journal of cardiovascular imaging 20110301

• Negative cooperativity in binding of muscarinic receptor agonists and GDP as a measure of agonist efficacy.

  British journal of pharmacology 20110301

• Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes.

  Biochimie 20110301

• Nucleic acid-based fluorescent probes and their analytical potential.

  Analytical and bioanalytical chemistry 20110301

• No shot in the dark: myxozoans chemically detect fresh fish.

  International journal for parasitology 20110301

• Gi/o-coupled receptors compete for signaling to adenylyl cyclase in SH-SY5Y cells and reduce opioid-mediated cAMP overshoot.

  Molecular pharmacology 20110301

• Advances in mass spectrometry-based post-column bioaffinity profiling of mixtures.

  Analytical and bioanalytical chemistry 20110301

• THRX-198321 is a bifunctional muscarinic receptor antagonist and beta2-adrenoceptor agonist (MABA) that binds in a bimodal and multivalent manner.

  Molecular pharmacology 20110301

• Microdomain-forming proteins and the role of the reggies/flotillins during axon regeneration in zebrafish.

  Biochimica et biophysica acta 20110301

• Lower oxidative DNA damage despite greater ROS production in muscles from rats selectively bred for high running capacity.

  American journal of physiology. Regulatory, integrative and comparative physiology 20110301

• Modulation by endogenously released ATP and opioids of chromaffin cell calcium channels in mouse adrenal slices.

  American journal of physiology. Cell physiology 20110301

• Active site mapping and substrate specificity of bacterial Hen1, a manganese-dependent 3' terminal RNA ribose 2'O-methyltransferase.

  RNA (New York, N.Y.) 20110301

• Inhibition of intestinal polyp formation by pitavastatin, a HMG-CoA reductase inhibitor.

  Cancer prevention research (Philadelphia, Pa.) 20110301

• The folylpolyglutamate synthetase plastidial isoform is required for postembryonic root development in Arabidopsis.

  Plant physiology 20110301

• Decreased cGMP level contributes to increased contraction in arteries from hypertensive rats: role of phosphodiesterase 1.

  Hypertension (Dallas, Tex. : 1979) 20110301

• Involvement of the lateral amygdala in the antiallodynic and reinforcing effects of heroin in rats after peripheral nerve injury.

  Anesthesiology 20110301

• Fluoride-cleavable, fluorescently labelled reversible terminators: synthesis and use in primer extension.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20110301

• Identification of dihalogenated proteins in rat intestinal mucosa injured by indomethacin.

  Journal of clinical biochemistry and nutrition 20110301

• Viral genome segmentation can result from a trade-off between genetic content and particle stability.

  PLoS genetics 20110301

• Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells.

  PLoS computational biology 20110301

• [Simultaneous determination of seven nucleosides and nucleobases in aqueous extracts of Fritillaria taipaiensis by HPLC-DAD].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110301

• Genetic and epigenetic alterations in pancreatic carcinogenesis.

  Current genomics 20110301

• Brown spider (Loxosceles genus) venom toxins: tools for biological purposes.

  Toxins 20110301

• Dynamics of corticosteroid receptors: lessons from live cell imaging.

  Acta histochemica et cytochemica 20110226

• Synthesis and pharmacological activities of 6-glycine substituted 14-phenylpropoxymorphinans, a novel class of opioids with high opioid receptor affinities and antinociceptive potencies.

  Journal of medicinal chemistry 20110224

• Probes for narcotic receptor mediated phenomena. 41. Unusual inverse μ-agonists and potent μ-opioid antagonists by modification of the N-substituent in enantiomeric 5-(3-hydroxyphenyl)morphans.

  Journal of medicinal chemistry 20110224

• Determination of the nucleosides and nucleobases in Tuber samples by dispersive solid-phase extraction combined with liquid chromatography-mass spectrometry.

  Analytica chimica acta 20110221

• Design and synthesis of highly solvatochromic fluorescent 2'-deoxyguanosine and 2'-deoxyadenosine analogs.

  Bioorganic & medicinal chemistry letters 20110215

• The muscarinic M(4) receptor is the functionally predominant subtype in rat and mouse striatum as demonstrated using [(35)S] GTPγS binding.

  European journal of pharmacology 20110210

• Residual effects of focal brain ischaemia upon cannabinoid CB(1) receptor density and functionality in female rats.

  Brain research 20110210

• Ionization of purine tautomers in nucleobases, nucleosides, and nucleotides: from the gas phase to the aqueous environment.

  The journal of physical chemistry. B 20110210

• Few constraints limit the design of quinone methide-oligonucleotide self-adducts for directing DNA alkylation.

  Chemical communications (Cambridge, England) 20110207

• Large ring polymers align FtsZ polymers for normal septum formation.

  The EMBO journal 20110202

• First report of GLUT1 deficiency syndrome in Chinese patients with novel and hot spot mutations in SLC2A1 gene.

  Brain & development 20110201

• A phase I study of OSI-461 in combination with mitoxantrone in patients with advanced solid tumors potentially responsive to mitoxantrone.

  Cancer chemotherapy and pharmacology 20110201

• Deletion of fucose residues in plant N-glycans by repression of the GDP-mannose 4,6-dehydratase gene using virus-induced gene silencing and RNA interference.

  Plant biotechnology journal 20110201

• Mycophenolic acid inhibits natural killer cell proliferation and cytotoxic function: a possible disadvantage of including mycophenolate mofetil in the graft-versus-host disease prophylaxis regimen.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110201

• Genetic, biochemical, and environmental factors associated with pregnancy outcomes in newborns from the Czech Republic.

  Environmental health perspectives 20110201

• Meeting report: Guanosines and quadruplexes (London, September 15-17, 2010).

  Biochimie 20110201

• Txe, an endoribonuclease of the enterococcal Axe-Txe toxin-antitoxin system, cleaves mRNA and inhibits protein synthesis.

  Microbiology (Reading, England) 20110201

• Differential effects of nitric oxide on blood-brain barrier integrity and cerebral blood flow in intracerebral C6 gliomas.

  Neuro-oncology 20110201

• Acycloguanosyl 5'-thymidyltriphosphate, a thymidine analogue prodrug activated by telomerase, reduces pancreatic tumor growth in mice.

  Gastroenterology 20110201

• The hydrolysis of striatal adenine- and guanine-based purines in a 6-hydroxydopamine rat model of Parkinson's disease.

  Neurochemical research 20110201

• Statin therapy in metabolic syndrome and hypertension post-JUPITER: what is the value of CRP?

  Current atherosclerosis reports 20110201

• An assay for RNA oxidation induced abasic sites using the Aldehyde Reactive Probe.

  Free radical research 20110201

• Advancing our understanding of functional genome organisation through studies in the fission yeast.

  Current genetics 20110201

• Levels of Gsα(short and long), Gα(olf) and Gβ(common) subunits, and calcium-sensitive adenylyl cyclase isoforms (1, 5/6, 8) in post-mortem human brain caudate and cortical membranes: comparison with rat brain membranes and potential stoichiometric relationships.

  Neurochemistry international 20110201

• Succinate independently stimulates full platelet activation via cAMP and phosphoinositide 3-kinase-β signaling.

  Journal of thrombosis and haemostasis : JTH 20110201

• Metamorphosis of subarachnoid hemorrhage research: from delayed vasospasm to early brain injury.

  Molecular neurobiology 20110201

• Identification of 17,20β,21-trihydroxy-4-pregnen-3-one (20β-S) receptor binding and membrane progestin receptor alpha on southern flounder sperm (Paralichthys lethostigma) and their likely role in 20β-S stimulation of sperm hypermotility.

  General and comparative endocrinology 20110201

• Development of infectious transcripts from full-length and GFP-tagged cDNA clones of Pepper mottle virus and stable systemic expression of GFP in tobacco and pepper.

  Virus research 20110201

• Yet another nucleoside analog for pancreatic cancer.

  Gastroenterology 20110201

• Angiotensin AT₂ receptor stimulation inhibits early renal inflammation in renovascular hypertension.

  Hypertension (Dallas, Tex. : 1979) 20110201

• Structural basis for c-di-GMP-mediated inside-out signaling controlling periplasmic proteolysis.

  PLoS biology 20110201

• In vitro assessment of the agonist properties of the novel 5-HT1A receptor ligand, CUMI-101 (MMP), in rat brain tissue.

  Nuclear medicine and biology 20110201

• Conformational changes in quadruplex oligonucleotide structures probed by Raman spectroscopy.

  Biomedical optics express 20110201

• Interrogation of a Sonogashira cross-coupling of 8-bromoguanosine with phenylacetylene on amberlite: evidence for Pd/Cu ion binding and propagation of Pd/Cu nanoparticles.

  Nucleosides, nucleotides & nucleic acids 20110201

• Genetic components of stringent response in Vibrio cholerae.

  The Indian journal of medical research 20110201

• Cytoskeletal dynamics: concepts in measles virus replication and immunomodulation.

  Viruses 20110201

• AKR1B7 is induced by the farnesoid X receptor and metabolizes bile acids.

  The Journal of biological chemistry 20110128

• Purification of heterotrimeric G protein alpha subunits by GST-Ric-8 association: primary characterization of purified G alpha(olf).

  The Journal of biological chemistry 20110128

• Ethanol extract of seeds of Oenothera odorata induces vasorelaxation via endothelium-dependent NO-cGMP signaling through activation of Akt-eNOS-sGC pathway.

  Journal of ethnopharmacology 20110127

• Systematic studies on the chemical structure and umami enhancing activity of Maillard-modified guanosine 5'-monophosphates.

  Journal of agricultural and food chemistry 20110126

• Structural and pharmacological analysis of O-2050, a putative neutral cannabinoid CB(1) receptor antagonist.

  European journal of pharmacology 20110125

• Oxidative damage is present in the fatal brain edema of diabetic ketoacidosis.

  Brain research 20110119

• Activation of the melanocortin-4 receptor causes enhanced excitation in presympathetic paraventricular neurons in obese Zucker rats.

  Regulatory peptides 20110117

• Highly sensitive electrochemiluminescent biosensor for adenosine based on structure-switching of aptamer.

  Analytica chimica acta 20110117

• Isolation of adenosine, iso-sinensetin and dimethylguanosine with antioxidant and HIV-1 protease inhibiting activities from fruiting bodies of Cordyceps militaris.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20110115

• Controlled synthesis of Pt nanoparticles array through electroreduction of cisplatin bound at nucleobases terminated surface and application into H2O2 sensing.

  Biosensors & bioelectronics 20110115

• Reversible organogels triggered by dynamic K+ binding and release.

  Journal of colloid and interface science 20110115

• Reference ranges of urinary biomarkers of oxidized guanine in (2'-deoxy)ribonucleotides and nucleic acids.

  Free radical biology & medicine 20110115

• Regulatory effects of ribosomal S6 kinase 1 (RSK1) in IFNλ signaling.

  The Journal of biological chemistry 20110114

• Organometallic anticancer compounds.

  Journal of medicinal chemistry 20110113

• Intracellular cAMP assay and Eu-GTP-γS binding studies of chimeric opioid peptide YFa.

  European journal of pharmacology 20110110

• Can guanine-based purines be considered modulators of intestinal motility in rodents?

  European journal of pharmacology 20110110

• Defining a process operating window for the synthesis of 5-methyluridine by transglycosylation of guanosine and thymine.

  Journal of biotechnology 20110110

• Design and synthesis of α-carboxy phosphononucleosides.

  The Journal of organic chemistry 20110107

• Mice with AS160/TBC1D4-Thr649Ala knockin mutation are glucose intolerant with reduced insulin sensitivity and altered GLUT4 trafficking.

  Cell metabolism 20110105

• S-Petasin, the Main Sesquiterpene of Petasites formosanus, Inhibits Phosphodiesterase Activity and Suppresses Ovalbumin-Induced Airway Hyperresponsiveness.

  Evidence-based complementary and alternative medicine : eCAM 20110101

• Decreased GABAA and GABAB receptor functional activity in cannabinoid CB1 receptor knockout mice.

  Journal of psychopharmacology (Oxford, England) 20110101

• Competitive interaction of 5-HT(1A) receptors with G-protein subtypes in CHO cells demonstrated by RNA interference.

  Cellular signalling 20110101

• A novel approach for stress-induced gastritis based on paradoxical anti-oxidative and anti-inflammatory action of exogenous 8-hydroxydeoxyguanosine.

  Biochemical pharmacology 20110101

• Phosphorylation of antiviral and endogenous nucleotides to di- and triphosphates by guanosine monophosphate kinase.

  Biochemical pharmacology 20110101

• Crosstalk between VEGFR2 and muscarinic receptors regulates the mTOR pathway in serum starved SK-N-SH human neuroblastoma cells.

  Cellular signalling 20110101

• Reactivity of mucohalic acids in water.

  Water research 20110101

• Changes in tear protein profile in patients with conjunctivochalasis.

  Cornea 20110101

• Exercise reduces oxidative stress but does not alleviate hyperinsulinemia or renal dopamine D1 receptor dysfunction in obese rats.

  American journal of physiology. Renal physiology 20110101

• Cyclic GMP kinase I modulates glucagon release from pancreatic α-cells.

  Diabetes 20110101

• Metabolic engineering and classic selection of the yeast Candida famata (Candida flareri) for construction of strains with enhanced riboflavin production.

  Metabolic engineering 20110101

• In vivo patch-clamp analysis of dopaminergic antinociceptive actions on substantia gelatinosa neurons in the spinal cord.

  Pain 20110101

• Pharmacological blockade of dopamine D2 receptors by aripiprazole is not associated with striatal sensitization.

  Naunyn-Schmiedeberg's archives of pharmacology 20110101

• Parecoxib and its metabolite valdecoxib directly interact with cannabinoid binding sites in CB1-expressing HEK 293 cells and rat brain tissue.

  Neurochemistry international 20110101

• Sensitive and selective fluorescence detection of guanosine nucleotides by nanoparticles conjugated with a naphthyridine receptor.

  Analytical and bioanalytical chemistry 20110101

• Antiviral therapy of CMV disease in children.

  Advances in experimental medicine and biology 20110101

• Millimolar Mn2+ influences agonist binding to 5-HT1A receptors by inhibiting guanosine nucleotide binding to receptor-coupled G-proteins.

  Neurotoxicology 20110101

• The role of system-specific molecular chaperones in the maturation of molybdoenzymes in bacteria.

  Biochemistry research international 20110101

• Purine nucleoside phosphorylase from Schistosoma mansoni in complex with ribose-1-phosphate.

  Journal of synchrotron radiation 20110101

• Tautomerization in gas-phase ion chemistry of isomeric C-8 deoxyguanosine adducts from phenol-induced DNA damage.

  Journal of mass spectrometry : JMS 20110101

• The Role of RUNX2 in Osteosarcoma Oncogenesis.

  Sarcoma 20110101

• Evaluation of overnight hold of whole blood at room temperature before component processing: effect of red blood cell (RBC) additive solutions on in vitro RBC measures.

  Transfusion 20110101

• Effect of additive solutions on red blood cell (RBC) membrane properties of stored RBCs prepared from whole blood held for 24 hours at room temperature.

  Transfusion 20110101

• Improving the predictive value of red blood cell storage trials: lessons from the Biomedical Excellence for Safer Transfusion (BEST) Collaborative Trial 41.

  Transfusion 20110101

• Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins.

  Genome biology 20110101

• Patterns and regulation of ribosomal RNA transcription in Borrelia burgdorferi.

  BMC microbiology 20110101

• Ribavirin potentiates interferon action by augmenting interferon-stimulated gene induction in hepatitis C virus cell culture models.

  Hepatology (Baltimore, Md.) 20110101

• Identification and characterization of seven new exon 11-associated splice variants of the rat μ opioid receptor gene, OPRM1.

  Molecular pain 20110101

• Identification of a key amino acid of LuxS involved in AI-2 production in Campylobacter jejuni.

  PloS one 20110101

• Phenotypic heterogeneity in mycobacterial stringent response.

  BMC systems biology 20110101

• Common genetic variants of MUTYH are not associated with cutaneous malignant melanoma: application of molecular screening by means of high-resolution melting technique in a pilot case-control study.

  The International journal of biological markers 20110101

• Sequencing and bioinformatics-based analyses of the microRNA transcriptome in hepatitis B-related hepatocellular carcinoma.

  PloS one 20110101

• Differential gene expression in liver and small intestine from lactating rats compared to age-matched virgin controls detects increased mRNA of cholesterol biosynthetic genes.

  BMC genomics 20110101

• Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention.

  Journal of clinical biochemistry and nutrition 20110101

• Nucleotides function as endogenous chemical sensors for oxidative stress signaling.

  Journal of clinical biochemistry and nutrition 20110101

• PDE 7 inhibitors: new potential drugs for the therapy of spinal cord injury.

  PloS one 20110101

• Impaired desensitization of a human polymorphic α2B-adrenergic receptor variant enhances its sympatho-inhibitory activity in chromaffin cells.

  Cell communication and signaling : CCS 20110101

• Protein kinase A type I activates a CRE-element more efficiently than protein kinase A type II regardless of C subunit isoform.

  BMC biochemistry 20110101

• Diagnostic properties of metabolic perturbations in rheumatoid arthritis.

  Arthritis research & therapy 20110101

• Cytosolic guanine nucledotide binding deficient form of transglutaminase 2 (R580a) potentiates cell death in oxygen glucose deprivation.

  PloS one 20110101

• RNA editing by mammalian ADARs.

  Advances in genetics 20110101

• Phospholipases A₁.

  International journal of molecular sciences 20110101

• NF-κB potentiates caspase independent hydrogen peroxide induced cell death.

  PloS one 20110101

• Possible role of the transglutaminases in the pathogenesis of Alzheimer's disease and other neurodegenerative diseases.

  International journal of Alzheimer's disease 20110101

• Biochemical and physiological characterization of the GTP-binding protein Obg of Mycobacterium tuberculosis.

  BMC microbiology 20110101

• Deep sequencing of the Camellia sinensis transcriptome revealed candidate genes for major metabolic pathways of tea-specific compounds.

  BMC genomics 20110101

• Biochemical identification of A-to-I RNA editing sites by the inosine chemical erasing (ICE) method.

  Methods in molecular biology (Clifton, N.J.) 20110101

• Therapeutic utility of phosphodiesterase type I inhibitors in neurological conditions.

  Frontiers in neuroscience 20110101

• Toll-like receptor pre-stimulation protects mice against lethal infection with highly pathogenic influenza viruses.

  Virology journal 20110101

• New implications on genomic adaptation derived from the Helicobacter pylori genome comparison.

  PloS one 20110101

• Post-transcriptional inhibition of hepatitis C virus replication through small interference RNA.

  Virology journal 20110101

• The regulatory subunit of PKA-I remains partially structured and undergoes β-aggregation upon thermal denaturation.

  PloS one 20110101

• Area, age and gender dependence of the nucleoside system in the brain: a review of current literature.

  Current topics in medicinal chemistry 20110101

• Metabolic network of nucleosides in the brain.

  Current topics in medicinal chemistry 20110101

• New developments in the treatment of hyperammonemia: emerging use of carglumic acid.

  International journal of general medicine 20110101

• Plant nucleoside 5'-phosphoramidate hydrolase; simple purification from yellow lupin (Lupinus luteus) seeds and properties of homogeneous enzyme.

  Acta biochimica Polonica 20110101

• Neurons controlling Aplysia feeding inhibit themselves by continuous NO production.

  PloS one 20110101

• Structural and spectral characteristics of the cross-linked dimer derived from electrooxidation of cyclic 1,N2-propanoguanosine.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20110101

• Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureus, Staphylococcus epidermidis and human cells.

  Genome biology 20110101

• Biochanin a, a phytoestrogenic isoflavone with selective inhibition of phosphodiesterase 4, suppresses ovalbumin-induced airway hyperresponsiveness.

  Evidence-based complementary and alternative medicine : eCAM 20110101

• Visualization of spatiotemporal energy dynamics of hippocampal neurons by mass spectrometry during a kainate-induced seizure.

  PloS one 20110101

• The zinc transporter SLC39A14/ZIP14 controls G-protein coupled receptor-mediated signaling required for systemic growth.

  PloS one 20110101

• Metabolites of purine nucleoside phosphorylase (NP) in serum have the potential to delineate pancreatic adenocarcinoma.

  PloS one 20110101

• Computational detection and functional analysis of human tissue-specific A-to-I RNA editing.

  PloS one 20110101

• Statins: cardiovascular risk reduction in percutaneous coronary intervention-basic and clinical evidence of hyperacute use of statins.

  International journal of hypertension 20110101

• Branched RNA: A New Architecture for RNA Interference.

  Journal of nucleic acids 20110101

• An overview of HCV molecular biology, replication and immune responses.

  Virology journal 20110101

• Chronic occupational exposure to hexavalent chromium causes DNA damage in electroplating workers.

  BMC public health 20110101

• The non-catalytic carboxyl-terminal domain of ARFGAP1 regulates actin cytoskeleton reorganization by antagonizing the activation of Rac1.

  PloS one 20110101

• Trafficking defect and proteasomal degradation contribute to the phenotype of a novel KCNH2 long QT syndrome mutation.

  PloS one 20110101

• Peripheral effects of morphine and expression of μ-opioid receptors in the dorsal root ganglia during neuropathic pain: nitric oxide signaling.

  Molecular pain 20110101

• Efficient silencing of gene expression by an ASON-bulge-DNAzyme complex.

  PloS one 20110101

• The stimulatory Gα(s) protein is involved in olfactory signal transduction in Drosophila.

  PloS one 20110101

• 1,2-propanediol-trehalose mixture as a potent quantitative real-time PCR enhancer.

  BMC biotechnology 20110101

• A framework and model system to investigate linear system behavior in Escherichia coli.

  Journal of biological engineering 20110101

• Isolation and characterization of Ehrlichia chaffeensis RNA polymerase and its use in evaluating p28 outer membrane protein gene promoters.

  BMC microbiology 20110101

• The antibiotic potential of prokaryotic IMP dehydrogenase inhibitors.

  Current medicinal chemistry 20110101

• Rab5a regulates surface expression of FcεRI and functional activation in mast cells.

  Biological & pharmaceutical bulletin 20110101

• Age-dependent maturation of Toll-like receptor-mediated cytokine responses in Gambian infants.

  PloS one 20110101

• Effect of reverse transcriptase inhibitors on LINE-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition.

  BMC biochemistry 20110101

• Occurrence and characteristics of group 1 introns found at three different positions within the 28S ribosomal RNA gene of the dematiaceous Phialophora verrucosa: phylogenetic and secondary structural implications.

  BMC microbiology 20110101

• Specific Silencing of L392V PSEN1 Mutant Allele by RNA Interference.

  International journal of Alzheimer's disease 20110101

• UMP/CMPK is not the critical enzyme in the metabolism of pyrimidine ribonucleotide and activation of deoxycytidine analogs in human RKO cells.

  PloS one 20110101

• Genome-wide dynamics of a bacterial response to antibiotics that target the cell envelope.

  BMC genomics 20110101

• Residue propensities, discrimination and binding site prediction of adenine and guanine phosphates.

  BMC biochemistry 20110101

• Down-regulation of IRES containing 5'UTR of HCV genotype 3a using siRNAs.

  Virology journal 20110101

• [Determination of nucleosides in Rhizoma Pinelliae by high performance liquid chromatography].

  Se pu = Chinese journal of chromatography 20110101

• Antioxidant potential of bitter cumin (Centratherum anthelminticum (L.) Kuntze) seeds in in vitro models.

  BMC complementary and alternative medicine 20110101

• Inhibition of Hazara nairovirus replication by small interfering RNAs and their combination with ribavirin.

  Virology journal 20110101

• Synaptically-competent neurons derived from canine embryonic stem cells by lineage selection with EGF and Noggin.

  PloS one 20110101

• Single-cell time-lapse analysis of depletion of the universally conserved essential protein YgjD.

  BMC microbiology 20110101

• Population pharmacokinetics and pharmacodynamics of hydroxyurea in sickle cell anemia patients, a basis for optimizing the dosing regimen.

  Orphanet journal of rare diseases 20110101

• Regulation of colonic ion transport by gasotransmitters.

  Biological & pharmaceutical bulletin 20110101

• Recent trends in pulmonary arterial hypertension.

  Lung India : official organ of Indian Chest Society 20110101

• Genetic and Immunological Factors Involved in Natural Resistance to HIV-1 Infection.

  The open virology journal 20110101

• Intimal hyperplasia in balloon dilated coronary arteries is reduced by local delivery of the NO donor, SIN-1 via a cGMP-dependent pathway.

  BMC cardiovascular disorders 20110101

• Zeranol down-regulates p53 expression in primary cultured human breast cancer epithelial cells through epigenetic modification.

  International journal of molecular sciences 20110101

• Mechanisms of estrogens' dose-dependent neuroprotective and neurodamaging effects in experimental models of cerebral ischemia.

  International journal of molecular sciences 20110101

• Combined 3D-QSAR, molecular docking and molecular dynamics study on derivatives of peptide epoxyketone and tyropeptin-boronic acid as inhibitors against the β5 subunit of human 20S proteasome.

  International journal of molecular sciences 20110101

• Gβγ subunits inhibit Epac-induced melanoma cell migration.

  BMC cancer 20110101

• Technologies and approaches to elucidate and model the virulence program of salmonella.

  Frontiers in microbiology 20110101

• Unexpected accumulation of ncm(5)U and ncm(5)S(2) (U) in a trm9 mutant suggests an additional step in the synthesis of mcm(5)U and mcm(5)S(2)U.

  PloS one 20110101

• Association between urinary excretion of cortisol and markers of oxidatively damaged DNA and RNA in humans.

  PloS one 20110101

• Activating effects of chronic variable stress in rats with different exploratory activity: association with dopamine d(1) receptor function in nucleus accumbens.

  Neuropsychobiology 20110101

• Analysis of the photosynthetic apparatus in transgenic tobacco plants with altered endogenous cytokinin content: a proteomic study.

  Proteome science 20110101

• Mechanical tuning of molecular machines for nucleotide recognition at the air-water interface.

  Nanoscale research letters 20110101

• A new drug design targeting the adenosinergic system for Huntington's disease.

  PloS one 20110101

• Use of specific chemical reagents for detection of modified nucleotides in RNA.

  Journal of nucleic acids 20110101

• Structural and functional basis for RNA cleavage by Ire1.

  BMC biology 20110101

• The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner.

  PloS one 20110101

• Genetic dissection of epidermal growth factor receptor signaling during luteinizing hormone-induced oocyte maturation.

  PloS one 20110101

• Genomic and protein structural maps of adaptive evolution of human influenza A virus to increased virulence in the mouse.

  PloS one 20110101

• Nitric Oxide-Soluble Guanylyl Cyclase-Cyclic GMP Signaling in the Striatum: New Targets for the Treatment of Parkinson's Disease?

  Frontiers in systems neuroscience 20110101

• Pseudomonas aeruginosa: resistance to the max.

  Frontiers in microbiology 20110101

• Molecular characterization of the uncultivatable hemotropic bacterium Mycoplasma haemofelis.

  Veterinary research 20110101

• E. coli histidine triad nucleotide binding protein 1 (ecHinT) is a catalytic regulator of D-alanine dehydrogenase (DadA) activity in vivo.

  PloS one 20110101

• Left ventricular hypertrophy: major risk factor in patients with hypertension: update and practical clinical applications.

  International journal of hypertension 20110101

• Pleiotropic effects of thyroid hormones: learning from hypothyroidism.

  Journal of thyroid research 20110101

• Glycyrrhizin as antiviral agent against Hepatitis C Virus.

  Journal of translational medicine 20110101

• The role of epigenetic alterations in papillary thyroid carcinogenesis.

  Journal of thyroid research 20110101

• Recent Perspectives on the Relations between Fecal Mutagenicity, Genotoxicity, and Diet.

  Frontiers in pharmacology 20110101

• Reduced cAMP, Akt activation and p65-c-Rel dimerization: mechanisms involved in the protective effects of mGluR3 agonists in cultured astrocytes.

  PloS one 20110101

• Evolution of small putative group I introns in the SSU rRNA gene locus of Phialophora species.

  BMC research notes 20110101

• Resurrection of an ancestral 5S rRNA.

  BMC evolutionary biology 20110101

• Variables and strategies in development of therapeutic post-transcriptional gene silencing agents.

  Journal of ophthalmology 20110101

• Gene targeting implicates Cdc42 GTPase in GPVI and non-GPVI mediated platelet filopodia formation, secretion and aggregation.

  PloS one 20110101

• Mutagenic Tests Confirm That New Acetylacetonate Pt(II) Complexes Induce Apoptosis in Cancer Cells Interacting with Nongenomic Biological Targets.

  Metal-based drugs 20110101

• Regulation of Inducible Nitric Oxide Synthase (iNOS) and its Potential Role in Insulin Resistance, Diabetes and Heart Failure.

  The open cardiovascular medicine journal 20110101

• Sequence-dependent fluorescence of cyanine dyes on microarrays.

  PloS one 20110101

• Interleukin-4 alters early phagosome phenotype by modulating class I PI3K dependent lipid remodeling and protein recruitment.

  PloS one 20110101

• Open-target sparse sensing of biological agents using DNA microarray.

  BMC bioinformatics 20110101

• A nuclear magnetic resonance based approach to accurate functional annotation of putative enzymes in the methanogen Methanosarcina acetivorans.

  BMC genomics 20110101

• Poly-thymidine oligonucleotides mediate activation of murine glial cells primarily through TLR7, not TLR8.

  PloS one 20110101

• Sulindac sulfide reverses aberrant self-renewal of progenitor cells induced by the AML-associated fusion proteins PML/RARα and PLZF/RARα.

  PloS one 20110101

• Lethal mutants and truncated selection together solve a paradox of the origin of life.

  PloS one 20110101

• Polyphosphate--an ancient energy source and active metabolic regulator.

  Microbial cell factories 20110101

• Therapeutic rescue of misfolded mutants: validation of primary high throughput screens for identification of pharmacoperone drugs.

  PloS one 20110101

• IPNV with high and low virulence: host immune responses and viral mutations during infection.

  Virology journal 20110101

• A computational study of elongation factor G (EFG) duplicated genes: diverged nature underlying the innovation on the same structural template.

  PloS one 20110101

• Evaluation of Abelmoschus moschatus extracts for antioxidant, free radical scavenging, antimicrobial and antiproliferative activities using in vitro assays.

  BMC complementary and alternative medicine 20110101

• The nucleotide exchange factor Ric-8A is a chaperone for the conformationally dynamic nucleotide-free state of Gαi1.

  PloS one 20110101

• In vitro and in vivo activity of ribavirin against Andes virus infection.

  PloS one 20110101

• LRRK2 kinase activity is dependent on LRRK2 GTP binding capacity but independent of LRRK2 GTP binding.

  PloS one 20110101

• Structural analysis of the essential resuscitation promoting factor YeaZ suggests a mechanism of nucleotide regulation through dimer reorganization.

  PloS one 20110101

• The kinase inhibitor SFV785 dislocates dengue virus envelope protein from the replication complex and blocks virus assembly.

  PloS one 20110101

• The RelA/SpoT homolog (RSH) superfamily: distribution and functional evolution of ppGpp synthetases and hydrolases across the tree of life.

  PloS one 20110101

• G-protein-associated signal transduction processes are restored after postweaning environmental enrichment in Ts65Dn, a Down syndrome mouse model.

  Developmental neuroscience 20110101

• Amoxapine inhibits delayed outward rectifier K(+) currents in cerebellar granule cells via dopamine receptor and protein kinase A activation.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101

• Comparison of the 'Ca. Liberibacter asiaticus' genome adapted for an intracellular lifestyle with other members of the Rhizobiales.

  PloS one 20110101

• Inverse association between methylation of human papillomavirus type 16 DNA and risk of cervical intraepithelial neoplasia grades 2 or 3.

  PloS one 20110101

• The TLR7/8 ligand resiquimod targets monocyte-derived dendritic cell differentiation via TLR8 and augments functional dendritic cell generation.

  Cellular immunology 20110101

• Optimisation of surface expression using the AIDA autotransporter.

  Microbial cell factories 20110101

• Specific interaction of Gαi3 with the Oa1 G-protein coupled receptor controls the size and density of melanosomes in retinal pigment epithelium.

  PloS one 20110101

• Virtual high-throughput screening identifies mycophenolic acid as a novel RNA capping inhibitor.

  PloS one 20110101

• Genome of Mycoplasma haemofelis, unraveling its strategies for survival and persistence.

  Veterinary research 20110101

• IL-4 amplifies the pro-inflammatory effect of adenosine in human mast cells by changing expression levels of adenosine receptors.

  PloS one 20110101

• Structural insights into the mechanism of protein O-fucosylation.

  PloS one 20110101

• A truncated form of SpoT, including the ACT domain, inhibits the production of cyclic lipopeptide arthrofactin, and is associated with moderate elevation of guanosine 3',5'-bispyrophosphate level in Pseudomonas sp. MIS38.

  Bioscience, biotechnology, and biochemistry 20110101

• Evolution under environmental stress at macro- and microscales.

  Genome biology and evolution 20110101

• Prenatal cocaine exposure increases synaptic localization of a neuronal RasGEF, GRASP-1 via hyperphosphorylation of AMPAR anchoring protein, GRIP.

  PloS one 20110101

• Neurochemical architecture of the central complex related to its function in the control of grasshopper acoustic communication.

  PloS one 20110101

• Development of vaccines against burkholderia pseudomallei.

  Frontiers in microbiology 20110101

• Genomic analysis reveals Lactobacillus sanfranciscensis as stable element in traditional sourdoughs.

  Microbial cell factories 20110101

• Genome sequences and comparative genomics of two Lactobacillus ruminis strains from the bovine and human intestinal tracts.

  Microbial cell factories 20110101

• Some aspects of purinergic signaling in the ventricular system of porcine brain.

  Acta veterinaria Scandinavica 20110101

• Replication of Epstein-Barr virus primary infection in human tonsil tissue explants.

  PloS one 20110101

• Synthesis of specifically modified oligonucleotides for application in structural and functional analysis of RNA.

  Journal of nucleic acids 20110101

• Identification of a predominant co-regulation among kinetochore genes, prospective regulatory elements, and association with genomic instability.

  PloS one 20110101

• The Fur regulon in anaerobically grown Salmonella enterica sv. Typhimurium: identification of new Fur targets.

  BMC microbiology 20110101

• Primary adenocarcinoma of the stomach in von Recklinghausen's disease with high serum levels of multiple tumor markers: a case report.

  Journal of medical case reports 20110101

• Differential effects of organic nitrates on arterial diameter among healthy Japanese participants with different mitochondrial aldehyde dehydrogenase 2 genotypes: randomised crossover trial.

  BMJ open 20110101

• Inverse agonism and its therapeutic significance.

  Indian journal of pharmacology 20110101

• Reduced nitrate level in individuals with hypertension and diabetes.

  Journal of cardiovascular disease research 20110101

• Foxf2: a novel locus for anterior segment dysgenesis adjacent to the Foxc1 gene.

  PloS one 20110101

• Analysis of RNA binding by the dengue virus NS5 RNA capping enzyme.

  PloS one 20110101

• Research advances on flotillins.

  Virology journal 20110101

• Inosine-containing RNA is a novel innate immune recognition element and reduces RSV infection.

  PloS one 20110101

• Cardiovascular and renal effects of carperitide and nesiritide in cardiovascular surgery patients: a systematic review and meta-analysis.

  Critical care (London, England) 20110101

• Enzymatic properties of Staphylococcus aureus adenosine synthase (AdsA).

  BMC biochemistry 20110101

• Rapid high yield production of different glycoforms of Ebola virus monoclonal antibody.

  PloS one 20110101

• UV-sensitive photoreceptor protein OPN5 in humans and mice.

  PloS one 20110101

• Novel agents for anti-platelet therapy.

  Journal of hematology & oncology 20110101

• Inhibition of striatal soluble guanylyl cyclase-cGMP signaling reverses basal ganglia dysfunction and akinesia in experimental parkinsonism.

  PloS one 20110101

• Hesperetin-7,3'-O-dimethylether selectively inhibits phosphodiesterase 4 and effectively suppresses ovalbumin-induced airway hyperresponsiveness with a high therapeutic ratio.

  Journal of biomedical science 20110101

• 8-Modified-2'-deoxyadenosine analogues induce delayed polymerization arrest during HIV-1 reverse transcription.

  PloS one 20110101

• Use of antimony in the treatment of leishmaniasis: current status and future directions.

  Molecular biology international 20110101

• Plasmodium falciparum parasites are killed by a transition state analogue of purine nucleoside phosphorylase in a primate animal model.

  PloS one 20110101

• Serum metabolic profile in multiple sclerosis patients.

  Multiple sclerosis international 20110101

• Microplate-based platform for combined chromatin and DNA methylation immunoprecipitation assays.

  BMC molecular biology 20110101

• The role of uridine adenosine tetraphosphate in the vascular system.

  Advances in pharmacological sciences 20110101

• Bluetongue virus VP1 polymerase activity in vitro: template dependency, dinucleotide priming and cap dependency.

  PloS one 20110101

• Subtype differences in pre-coupling of muscarinic acetylcholine receptors.

  PloS one 20110101

• Ribavirin enhances IFN-α signalling and MxA expression: a novel immune modulation mechanism during treatment of HCV.

  PloS one 20110101

• Retinal degeneration modulates intracellular localization of CDC42 in photoreceptors.

  Molecular vision 20110101

• Targeting of mitochondria-endoplasmic reticulum by fluorescent macrocyclic compounds.

  PloS one 20110101

• Non-invasive epigenetic detection of fetal trisomy 21 in first trimester maternal plasma.

  PloS one 20110101

• A practical approach to T-cell receptor cloning and expression.

  PloS one 20110101

• Putting the pH into phosphatidic acid signaling.

  BMC biology 20110101

• Modulation of the host interferon response and ISGylation pathway by B. pertussis filamentous hemagglutinin.

  PloS one 20110101

• Raloxifene and desmethylarzoxifene block estrogen-induced malignant transformation of human breast epithelial cells.

  PloS one 20110101

• A knockout mutation of a constitutive GPCR in Tetrahymena decreases both G-protein activity and chemoattraction.

  PloS one 20110101

• Frontiers of Retrovirology 2011, Amsterdam, The Netherlands, 3-5 October 2011. Meeting Abstracts.

  Retrovirology 20110101

• Docking studies on novel analogues of 8 methoxy fluoroquinolones against GyrA mutants of Mycobacterium tuberculosis.

  BMC structural biology 20110101

• Phasevarion mediated epigenetic gene regulation in Helicobacter pylori.

  PloS one 20110101

• ZipA binds to FtsZ with high affinity and enhances the stability of FtsZ protofilaments.

  PloS one 20110101

• [Pathogenicity factors of bacteria with glycosylating activity].

  Vestnik Rossiiskoi akademii meditsinskikh nauk 20110101

• Modulation of phosducin-like protein 3 (PhLP3) levels promotes cytoskeletal remodelling in a MAPK and RhoA-dependent manner.

  PloS one 20110101

• Flip-flop of phospholipids in proteoliposomes reconstituted from detergent extract of chloroplast membranes: kinetics and phospholipid specificity.

  PloS one 20110101

• Breaking the cycle: An insight into the role of ERα in eukaryotic cell cycles.

  Journal of carcinogenesis 20110101

• PPAR-α Agonist Fenofibrate Upregulates Tetrahydrobiopterin Level through Increasing the Expression of Guanosine 5'-Triphosphate Cyclohydrolase-I in Human Umbilical Vein Endothelial Cells.

  PPAR research 20110101

• Autophagy in inflammatory diseases.

  International journal of cell biology 20110101

• Rapid S-nitrosylation of actin by NO-generating donors and in inflammatory pain model mice.

  Molecular pain 20110101

• Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays.

  PloS one 20110101

• Induction of cytoplasmic rods and rings structures by inhibition of the CTP and GTP synthetic pathway in mammalian cells.

  PloS one 20110101

• A genomic reappraisal of symbiotic function in the aphid/Buchnera symbiosis: reduced transporter sets and variable membrane organisations.

  PloS one 20110101

• Structural dynamics of retroviral genome and the packaging.

  Frontiers in microbiology 20110101

• [Design of Streptomyces nogalater LV65 strains with higher synthesis of nogalamicin using regulatory genes].

  Prikladnaia biokhimiia i mikrobiologiia 20110101

• Mthfs is an Essential Gene in Mice and a Component of the Purinosome.

  Frontiers in genetics 20110101

• MicroRNAs as New Characters in the Plot between Epigenetics and Prostate Cancer.

  Frontiers in genetics 20110101

• Epigenetic Contributions to the Relationship between Cancer and Dietary Intake of Nutrients, Bioactive Food Components, and Environmental Toxicants.

  Frontiers in genetics 20110101

• Feline and canine coronaviruses: common genetic and pathobiological features.

  Advances in virology 20110101

• Signal protein-derived peptides as functional probes and regulators of intracellular signaling.

  Journal of amino acids 20110101

• Developing central nervous system and vulnerability to platinum compounds.

  Chemotherapy research and practice 20110101

• Plasma cyclic guanosine 3',5'-monophosphate levels: a marker of glutamate-nitric oxide-guanyl cyclase activity?

  Journal of opioid management 20110101

• Single-molecule sensing electrode embedded in-plane nanopore.

  Scientific reports 20110101

• The role of nitrogen oxides in human adaptation to hypoxia.

  Scientific reports 20110101

• Genome-wide essential gene identification in Streptococcus sanguinis.

  Scientific reports 20110101

• Novel base triples in RNA structures revealed by graph theoretical searching methods.

  BMC bioinformatics 20110101

• Structure-based and ligand-based virtual screening of novel methyltransferase inhibitors of the dengue virus.

  BMC bioinformatics 20110101

• [Some inhibitors of purine nucleoside phosphorylase].

  Biomeditsinskaia khimiia 20110101

• Mining Functional Elements in Messenger RNAs: Overview, Challenges, and Perspectives.

  Frontiers in plant science 20110101

• Drug discovery opportunities and challenges at g protein coupled receptors for long chain free Fatty acids.

  Frontiers in endocrinology 20110101

• Defying the stereotype: non-canonical roles of the Peptide hormones guanylin and uroguanylin.

  Frontiers in endocrinology 20110101

• Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts.

  Science signaling 20101221

• Insights into nucleotide recognition by cell division protein FtsZ from a mant-GTP competition assay and molecular dynamics.

  Biochemistry 20101214

• Ligand-directed trafficking of the δ-opioid receptor in vivo: two paths toward analgesic tolerance.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20101208

• Inhibition of microglial and astrocytic inflammatory responses by the immunosuppressant mycophenolate mofetil.

  Neuropathology and applied neurobiology 20101201

• Reduction of oxidized guanosine by dietary carotenoids: a pulse radiolysis study.

  Archives of biochemistry and biophysics 20101201

• Adenine, guanine and pyridine nucleotides in blood during physical exercise and restitution in healthy subjects.

  European journal of applied physiology 20101201

• 6S RNA regulation of relA alters ppGpp levels in early stationary phase.

  Microbiology (Reading, England) 20101201

• The cellular mechanisms underlying the inhibitory effects of isoflurane and sevoflurane on arginine vasopressin-induced vasoconstriction.

  Journal of anesthesia 20101201

• Electrophysiological analysis of the inhibitory effects of FMRFamide-like peptides on the pacemaker activity of gonadotropin-releasing hormone neurons.

  Journal of neurophysiology 20101201

• pex5 Mutants that differentially disrupt PTS1 and PTS2 peroxisomal matrix protein import in Arabidopsis.

  Plant physiology 20101201

• Nucleotide and nucleotide sugar analysis by liquid chromatography-electrospray ionization-mass spectrometry on surface-conditioned porous graphitic carbon.

  Analytical chemistry 20101201

• Profiles of purine metabolism in leaves and roots of Camellia sinensis seedlings.

  Plant & cell physiology 20101201

• Brain energy metabolism during experimental neonatal seizures.

  Neurochemical research 20101201

• A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress.

  PLoS genetics 20101201

• Gene expression profiling in rodent models for schizophrenia.

  Current neuropharmacology 20101201

• Acceptor substrate discrimination in phosphatidyl-myo-inositol mannoside synthesis: structural and mutational analysis of mannosyltransferase Corynebacterium glutamicum PimB'.

  The Journal of biological chemistry 20101126

• The effect of Δ9-tetrahydrocannabinol on 5-HT3 receptors depends on the current density.

  Neuroscience 20101124

• ARFGAP2 and ARFGAP3 are essential for COPI coat assembly on the Golgi membrane of living cells.

  The Journal of biological chemistry 20101119

• 2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members.

  Nature 20101118

• The F-BAR domain of SRGP-1 facilitates cell-cell adhesion during C. elegans morphogenesis.

  The Journal of cell biology 20101115

• Gas-phase isolation of diethyl guanosine 5'-monophosphate and its conformational assignment.

  Physical chemistry chemical physics : PCCP 20101114

• Phosphoramidate prodrugs deliver with potency against hepatitis C virus.

  ChemMedChem 20101108

• Molecular organization and dynamics of the melatonin MT₁ receptor/RGS20/G(i) protein complex reveal asymmetry of receptor dimers for RGS and G(i) coupling.

  The EMBO journal 20101103

• Enantioselective recognition between polydiacetylene nucleolipid monolayers and complementary oligonucleotides.

  Langmuir : the ACS journal of surfaces and colloids 20101102

• Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues.

  Neuropharmacology 20101101

• An improved red blood cell additive solution maintains 2,3-diphosphoglycerate and adenosine triphosphate levels by an enhancing effect on phosphofructokinase activity during cold storage.

  Transfusion 20101101

• Calculations of binding affinity between C8-substituted GTP analogs and the bacterial cell-division protein FtsZ.

  European biophysics journal : EBJ 20101101

• Construction of a dengue virus type 4 reporter replicon and analysis of temperature-sensitive mutations in non-structural proteins 3 and 5.

  The Journal of general virology 20101101

• Use of the GTPγS ([35S]GTPγS and Eu-GTPγS) binding assay for analysis of ligand potency and efficacy at G protein-coupled receptors.

  British journal of pharmacology 20101101

• Comparison of the pharmacological properties of human and rat histamine H(3)-receptors.

  Biochemical pharmacology 20101101

• A silk platform that enables electrophysiology and targeted drug delivery in brain astroglial cells.

  Biomaterials 20101101

• Loxoribine, a selective Toll-like receptor 7 agonist, induces maturation of human monocyte-derived dendritic cells and stimulates their Th-1- and Th-17-polarizing capability.

  International immunopharmacology 20101101

• Renal function and vasomotor activity in mice lacking the Cyp4a14 gene.

  Experimental biology and medicine (Maywood, N.J.) 20101101

• A post-burst after depolarization is mediated by group i metabotropic glutamate receptor-dependent upregulation of Ca(v)2.3 R-type calcium channels in CA1 pyramidal neurons.

  PLoS biology 20101101

• Regulation of Na+/K+ ATPase transport velocity by RNA editing.

  PLoS biology 20101101

• G-octamer formation from N⁹ modified guanine derivatives.

  Nucleosides, nucleotides & nucleic acids 20101101

• Synthesis and substrate validation of cap analogs containing 7-deazaguanosine moiety by RNA polymerase.

  Nucleosides, nucleotides & nucleic acids 20101101

• Making of viral replication organelles by remodeling interior membranes.

  Viruses 20101101

• Modulatory Role of Nitric Oxide/cGMP System in Endothelin-1-Induced Signaling Responses in Vascular Smooth Muscle Cells.

  Current cardiology reviews 20101101

• Modulation of Gi Proteins in Hypertension: Role of Angiotensin II and Oxidative Stress.

  Current cardiology reviews 20101101

• Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells.

  The Journal of biological chemistry 20101022

• Oligo-guanosine nucleotide induces neuropilin-1 internalization in endothelial cells and inhibits angiogenesis.

  Blood 20101021

• Refinement of DNA structures through near-edge X-ray absorption fine structure analysis: applications on guanine and cytosine nucleobases, nucleosides, and nucleotides.

  The journal of physical chemistry. B 20101021

• Inhibitory effect of the natural product betulin and its derivatives against the intracellular bacterium Chlamydia pneumoniae.

  Biochemical pharmacology 20101015

• One-pot etherification of purine nucleosides and pyrimidines.

  Organic letters 20101015

• Method for the rapid detection and molecular characterization of DNA alkylating agents by MALDI-TOF mass spectrometry.

  Analytical chemistry 20101015

• Discovery of N(2)-(1-carboxyethyl)guanosine 5'-monophosphate as an umami-enhancing maillard-modified nucleotide in yeast extracts.

  Journal of agricultural and food chemistry 20101013

• G protein-mediated Ca²+-sensitization of CPI-17 phosphorylation in arterial smooth muscle.

  Biochemical and biophysical research communications 20101008

• Extreme nucleoside concentrations in a marine annelid: a novel nucleoside storing cell in the polychaete Nereis virens.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20101001

• Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?

  Leukemia & lymphoma 20101001

• Redox regulatory mechanism of transnitrosylation by thioredoxin.

  Molecular & cellular proteomics : MCP 20101001

• A homogeneous method to measure nucleotide exchange by α-subunits of heterotrimeric G-proteins using fluorescence polarization.

  Assay and drug development technologies 20101001

• Metabolomic profiling reveals biochemical pathways and biomarkers associated with pathogenesis in cystic fibrosis cells.

  The Journal of biological chemistry 20101001

• In situ evaluation of chromium-DNA damage using a DNA-electrochemical biosensor.

  Analytical and bioanalytical chemistry 20101001

• Modulation of N-type calcium currents by presynaptic imidazoline receptor activation in rat superior cervical ganglion neurons.

  Experimental physiology 20101001

• Transcription regulation of the Escherichia coli pcnB gene coding for poly(A) polymerase I: roles of ppGpp, DksA and sigma factors.

  Molecular genetics and genomics : MGG 20101001

• Investigation of riboflavin sensitized degradation of purine and pyrimidine derivatives of DNA and RNA under UVA and UVB.

  Biochemical and biophysical research communications 20101001

• A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses.

  Nature structural & molecular biology 20101001

• Colon tumor cell growth-inhibitory activity of sulindac sulfide and other nonsteroidal anti-inflammatory drugs is associated with phosphodiesterase 5 inhibition.

  Cancer prevention research (Philadelphia, Pa.) 20101001

• Efficient synthesis of the tRNA nucleoside preQ0, 7-cyano-7-deazaguanosine, via microwave-assisted iodo→carbonitrile exchange.

  Chemistry & biodiversity 20101001

• Identification of a quality-control mechanism for mRNA 5'-end capping.

  Nature 20100930

• Human kisspeptins activate neuropeptide FF2 receptor.

  Neuroscience 20100929

• Characterization of caged compounds binding to proteins by NMR spectroscopy.

  Biochemical and biophysical research communications 20100924

• The 5'-7-methylguanosine cap on eukaryotic mRNAs serves both to stimulate canonical translation initiation and to block an alternative pathway.

  Molecular cell 20100924

• Development and application of an HILIC-MS/MS method for the quantitation of nucleotides in infant formula.

  Journal of agricultural and food chemistry 20100922

• Comparisons between chemical mapping and binding to isoenergetic oligonucleotide microarrays reveal unexpected patterns of binding to the Bacillus subtilis RNase P RNA specificity domain.

  Biochemistry 20100921

• Structure of the RNA binding domain of a DEAD-box helicase bound to its ribosomal RNA target reveals a novel mode of recognition by an RNA recognition motif.

  Journal of molecular biology 20100917

• Electrocatalytic oxidation behavior of guanosine at graphene, chitosan and Fe3O4 nanoparticles modified glassy carbon electrode and its determination.

  Talanta 20100915

• Methylated DNA causes a physical block to replication forks independently of damage signalling, O(6)-methylguanine or DNA single-strand breaks and results in DNA damage.

  Journal of molecular biology 20100910

• Cortical M1 receptor concentration increases without a concomitant change in function in Alzheimer's disease.

  Journal of chemical neuroanatomy 20100901

• Biosynthesis of wyosine derivatives in tRNA: an ancient and highly diverse pathway in Archaea.

  Molecular biology and evolution 20100901

• Endothelin A receptors mediate relaxation of guinea pig internal anal sphincter through cGMP pathway.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20100901

• Antiproliferative effects induced by guanine-based purines require hypoxanthine-guanine phosphoribosyltransferase activity.

  Biological chemistry 20100901

• Reversal of TNP-470-induced endothelial cell growth arrest by guanine and guanine nucleosides.

  The Journal of pharmacology and experimental therapeutics 20100901

• Pegylated interferons alpha2a and alpha2b in the treatment of chronic hepatitis C.

  Nature reviews. Gastroenterology & hepatology 20100901

• Adeno-associated viral vector-induced overexpression of neuropeptide Y Y2 receptors in the hippocampus suppresses seizures.

  Brain : a journal of neurology 20100901

• Coupling between clathrin-dependent endocytic budding and F-BAR-dependent tubulation in a cell-free system.

  Nature cell biology 20100901

• Azole drugs are imported by facilitated diffusion in Candida albicans and other pathogenic fungi.

  PLoS pathogens 20100901

• Cure and curse: E. coli heat-stable enterotoxin and its receptor guanylyl cyclase C.

  Toxins 20100901

• Actions of the prototypical 5-HT1A receptor agonist 8-OH-DPAT at human alpha2-adrenoceptors: (+)8-OH-DPAT, but not (-)8-OH-DPAT is an alpha2B subtype preferential agonist.

  European journal of pharmacology 20100825

• Acute withdrawal from chronic escalating-dose binge cocaine administration alters kappa opioid receptor stimulation of [35S] guanosine 5'-O-[gamma-thio]triphosphate acid binding in the rat ventral tegmental area.

  Neuroscience 20100825

• Endothelin-1 (ET-1) increases the expression of remodeling genes in vascular smooth muscle through linked calcium and cAMP pathways: role of a phospholipase A(2)(cPLA(2))/cyclooxygenase-2 (COX-2)/prostacyclin receptor-dependent autocrine loop.

  The Journal of biological chemistry 20100820

• Determination of nucleotides, nucleosides and their transformation products in Cordyceps by ion-pairing reversed-phase liquid chromatography-mass spectrometry.

  Journal of chromatography. A 20100820

• 3'-5' tRNAHis guanylyltransferase in bacteria.

  FEBS letters 20100820

• Synthesis of nucleotidylated poliovirus VPg proteins.

  The Journal of organic chemistry 20100820

• G-protein-independent modulation of P-type calcium channels by mu-opioids in Purkinje neurons of rat.

  Neuroscience letters 20100816

• Comparison of the in vitro replication of the 7-(2-oxoheptyl)-1,N2-etheno-2'-deoxyguanosine and 1,N2-etheno-2'-deoxyguanosine lesions by Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4).

  Chemical research in toxicology 20100816

• Design, synthesis and evaluation of a novel double pro-drug: INX-08189. A new clinical candidate for hepatitis C virus.

  Bioorganic & medicinal chemistry letters 20100815

• Ion-pair high-performance liquid chromatography with diode array detection coupled to dual electrospray atmospheric pressure chemical ionization time-of-flight mass spectrometry for the determination of nucleotides in baby foods.

  Journal of chromatography. A 20100806

• Agonist-dependent modulation of G-protein coupling and transduction of 5-HT1A receptors in rat dorsal raphe nucleus.

  The international journal of neuropsychopharmacology 20100801

• Δ⁹-Tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rats.

  Epilepsia 20100801

• Antioxidant defenses in the rat placenta in late gestation: increased labyrinthine expression of superoxide dismutases, glutathione peroxidase 3, and uncoupling protein 2.

  Biology of reproduction 20100801

• Ex vivo delta opioid receptor autoradiography: CNS receptor occupancy of two novel compounds over their antihyperalgesic dose range.

  Pharmacology, biochemistry, and behavior 20100801

• Gi protein coupling to adenosine A1-A2A receptor heteromers in human brain caudate nucleus.

  Journal of neurochemistry 20100801

• Creation of a genome-wide metabolic pathway database for Populus trichocarpa using a new approach for reconstruction and curation of metabolic pathways for plants.

  Plant physiology 20100801

• Guanosine 5'-diphosphate 3'-diphosphate (ppGpp) as a negative modulator of polynucleotide phosphorylase activity in a 'rare' actinomycete.

  Molecular microbiology 20100801

• Decreased expression of spine-associated Rap guanosine triphosphatase-activating protein (SPAR) in glutamate-treated primary hippocampal neurons.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20100801

• Self-quenching smart probes as a platform for the detection of sequence-specific UV-induced DNA photodamage.

  Analytical and bioanalytical chemistry 20100801

• Resistance to endotoxic shock in mice lacking natriuretic peptide receptor-A.

  British journal of pharmacology 20100801

• Molecular cloning, chromosomal localization and expression pattern of porcine ADP-ribosylation factor(Arf) gene family.

  Animal science journal = Nihon chikusan Gakkaiho 20100801

• Involvement of kappa opioid receptors in the formalin-induced inhibition of analgesic tolerance to morphine via suppression of conventional protein kinase C activation.

  The Journal of pharmacy and pharmacology 20100801

• Long-term adaptation to high doses of morphine causes desensitization of mu-OR- and delta-OR-stimulated G-protein response in forebrain cortex but does not decrease the amount of G-protein alpha subunits.

  Medical science monitor : international medical journal of experimental and clinical research 20100801

• Trichomonas transmembrane cyclases result from massive gene duplication and concomitant development of pseudogenes.

  PLoS neglected tropical diseases 20100801

• A screening pipeline for antiparasitic agents targeting cryptosporidium inosine monophosphate dehydrogenase.

  PLoS neglected tropical diseases 20100801

• Nucleotides in canine colostrum and milk at different stages of lactation.

  Archives of animal nutrition 20100801

• Direct effect of carbon monoxide on relaxation induced by electrical field stimulation in rat corpus cavernosum.

  Korean journal of urology 20100801

• [Simultaneous determination of 7 nucleosides in Asterias rollestoni using reversed-phase high performance liquid chromatography].

  Se pu = Chinese journal of chromatography 20100801

• Combination chemotherapy for influenza.

  Viruses 20100801

• Possibilities for RNA interference in developing hepatitis C virus therapeutics.

  Viruses 20100801

• Bacterial heat-stable enterotoxins: translation of pathogenic peptides into novel targeted diagnostics and therapeutics.

  Toxins 20100801

• Assessment of the role of renal organic anion transporters in drug-induced nephrotoxicity.

  Toxins 20100801

• Crystal structure of human RNA helicase A (DHX9): structural basis for unselective nucleotide base binding in a DEAD-box variant protein.

  Journal of molecular biology 20100723

• Regulation of redox signaling involving chemical conjugation of protein thiols by nitric oxide and electrophiles.

  Bioconjugate chemistry 20100721

• Design of single-stranded nucleic acid binding peptides based on nucleocapsid CCHC-box zinc-binding domains.

  Journal of the American Chemical Society 20100721

• Structural basis for conformational dynamics of GTP-bound Ras protein.

  The Journal of biological chemistry 20100716

• (15)N Double-labeled guanosine from inosine through ring-opening-ring-closing and one-pot Pd-catalyzed C-O and C-N cross-coupling reactions.

  The Journal of organic chemistry 20100716

• cGMP is required for seed germination in Arabidopsis thaliana.

  Journal of plant physiology 20100715

• A real-time fluorescent assay of the purified nitric oxide receptor, guanylyl cyclase.

  Analytical biochemistry 20100715

• RNA internal loops with tandem AG pairs: the structure of the 5'GAGU/3'UGAG loop can be dramatically different from others, including 5'AAGU/3'UGAA.

  Biochemistry 20100713

• Phosphoramidate ProTides of 2'-C-methylguanosine as highly potent inhibitors of hepatitis C virus. Study of their in vitro and in vivo properties.

  Journal of medicinal chemistry 20100708

• Cytidylyl and uridylyl cyclase activity of bacillus anthracis edema factor and Bordetella pertussis CyaA.

  Biochemistry 20100706

• Activated RhoA binds to the pleckstrin homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation.

  The Journal of biological chemistry 20100702

• Human BLCAP transcript: new editing events in normal and cancerous tissues.

  International journal of cancer 20100701

• Selective alterations of the CB1 receptors and the fatty acid amide hydrolase in the ventral striatum of alcoholics and suicides.

  Journal of psychiatric research 20100701

• Efficient expression of human soluble guanylate cyclase in Escherichia coli and its signaling-related interaction with nitric oxide.

  Amino acids 20100701

• Nociceptin inhibits uterine contractions in term-pregnant rats by signaling through multiple pathways.

  Biology of reproduction 20100701

• Interaction of oligonucleotide-based amphiphilic block copolymers with cell membrane models.

  Journal of colloid and interface science 20100701

• FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100701

• Stress impairs GABAergic network function in the hippocampus by activating nongenomic glucocorticoid receptors and affecting the integrity of the parvalbumin-expressing neuronal network.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100701

• Nitric oxide and downstream second messenger cGMP and cAMP enhance adipogenesis in primary human preadipocytes.

  Cytotherapy 20100701

• Atrial natriuretic peptide and oxidative stress.

  Peptides 20100701

• Oxidation of the diphosphoinositol polyphosphate phosphohydrolase-like Nudix hydrolase Aps from Drosophila melanogaster induces thermolability--A possible regulatory switch?

  The international journal of biochemistry & cell biology 20100701

• A novel nucleoside analog, 1-beta-d-ribofuranosyl-3-ethynyl-[1,2,4]triazole (ETAR), exhibits efficacy against a broad range of flaviviruses in vitro.

  Antiviral research 20100701

• Famciclovir: a focus on efficacy and safety.

  Expert opinion on drug safety 20100701

• The acidic A-domain of Arabidopsis TOC159 occurs as a hyperphosphorylated protein.

  Plant physiology 20100701

• The sigma(E) stress response is required for stress-induced mutation and amplification in Escherichia coli.

  Molecular microbiology 20100701

• Pharmacological characterization of a novel cannabinoid ligand, MDA19, for treatment of neuropathic pain.

  Anesthesia and analgesia 20100701

• Structural requirements for Caenorhabditis elegans DcpS substrates based on fluorescence and HPLC enzyme kinetic studies.

  The FEBS journal 20100701

• Oxidative stress markers in the brain of patients with cirrhosis and hepatic encephalopathy.

  Hepatology (Baltimore, Md.) 20100701

• A metazoan/plant-like capping enzyme and cap modified nucleotides in the unicellular eukaryote Trichomonas vaginalis.

  PLoS pathogens 20100701

• Resistance to integrase inhibitors.

  Viruses 20100701

• New trends in nucleoside biotechnology.

  Acta naturae 20100701

• Analysis of seven purines and pyrimidines in pork meat products by ultra high performance liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. A 20100625

• Direct measurement of the rates and barriers on forward and reverse diffusions of intramolecular collision in overhang oligonucleotides.

  The journal of physical chemistry. B 20100624

• Rab14 from Bombyx mori (Lepidoptera: Bombycidae) shows ATPase activity.

  Biology letters 20100623

• Chronic constriction injury reduces cannabinoid receptor 1 activity in the rostral anterior cingulate cortex of mice.

  Brain research 20100621

• A non-empirical chromophoric interpretation of CD spectra of DNA G-quadruplex structures.

  Organic & biomolecular chemistry 20100621

• Structure and gelation mechanism of tunable guanosine-based supramolecular hydrogels.

  Langmuir : the ACS journal of surfaces and colloids 20100615

• The oxidation of 8-oxo-7,8-dihydroguanine by iodine.

  Bioorganic & medicinal chemistry letters 20100615

• ppGpp analogues inhibit synthetase activity of Rel proteins from Gram-negative and Gram-positive bacteria.

  Bioorganic & medicinal chemistry 20100615

• Cost of unneeded proteins in E. coli is reduced after several generations in exponential growth.

  Molecular cell 20100611

• Extracellular cAMP inhibits P2X receptors in rat sensory neurones through G protein-mediated mechanism.

  Acta physiologica (Oxford, England) 20100601

• Mechanism for the regulation of mammalian cGMP phosphodiesterase6. 2: isolation and characterization of the transducin-activated form.

  Molecular and cellular biochemistry 20100601

• HL-1 cells express an inwardly rectifying K+ current activated via muscarinic receptors comparable to that in mouse atrial myocytes.

  Pflugers Archiv : European journal of physiology 20100601

• Hydrogen-bond-directed giant vesicles of guanosine derivatives in water: formation, structure, and stability.

  Langmuir : the ACS journal of surfaces and colloids 20100601

• Novel anticytomegalovirus activity of immunosuppressant mizoribine and its synergism with ganciclovir.

  The Journal of pharmacology and experimental therapeutics 20100601

• Meiotic cell cycle arrest in mammalian oocytes.

  Journal of cellular physiology 20100601

• A fluorescence anisotropy assay for the muscarinic M1 G-protein-coupled receptor.

  Assay and drug development technologies 20100601

• NADPH-diaphorase activity and NO synthase expression in the olfactory epithelium of the bovine.

  Anatomia, histologia, embryologia 20100601

• SNARE-dependent glutamate release in megakaryocytes.

  Experimental hematology 20100601

• Kappa opioid mediation of cannabinoid effects of the potent hallucinogen, salvinorin A, in rodents.

  Psychopharmacology 20100601

• Specific oxidative stress profile associated with partial striatal dopaminergic depletion by 6-hydroxydopamine as assessed by a novel multifunctional marker molecule.

  Free radical research 20100601

• Absence of mitochondrial toxicity in hearts of transgenic mice treated with abacavir.

  Cardiovascular toxicology 20100601

• Inhibition of G-protein-activated inwardly rectifying K+ channels by the selective norepinephrine reuptake inhibitors atomoxetine and reboxetine.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100601

• Electrochemical simulation of oxidation processes involving nucleic acids monitored with electrospray ionization-mass spectrometry.

  Analytical and bioanalytical chemistry 20100601

• Simultaneous determination of nine nucleosides and nucleobases in different Fritillaria species by HPLC-diode array detector.

  Journal of separation science 20100601

• Homologous desensitization of guanylyl cyclase A, the receptor for atrial natriuretic peptide, is associated with a complex phosphorylation pattern.

  The FEBS journal 20100601

• A point mutation in the polymerase of Potato virus Y confers virulence toward the Pvr4 resistance of pepper and a high competitiveness cost in susceptible cultivar.

  Molecular plant-microbe interactions : MPMI 20100601

• Synthesis of new derivatives of 8-oxoG-clamp for better understanding the recognition mode and improvement of selective affinity.

  Bioorganic & medicinal chemistry 20100601

• Nucleotides and nucleosides in ovine and caprine milk during lactation.

  Journal of dairy science 20100601

• A role for borg5 during trophectoderm differentiation.

  Stem cells (Dayton, Ohio) 20100601

• Evaluation of activation of G proteins in response to thyroid stimulating hormone in thyroid gland cells from euthyroid and hyperthyroid cats.

  American journal of veterinary research 20100601

• Preparation of DNA and RNA fragments containing guanine N(2)-thioalkyl tethers.

  Current protocols in nucleic acid chemistry 20100601

• Two novel point mutations in clinical Staphylococcus aureus reduce linezolid susceptibility and switch on the stringent response to promote persistent infection.

  PLoS pathogens 20100601

• The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice.

  British journal of pharmacology 20100601

• A role for L-alpha-lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells.

  British journal of pharmacology 20100601

• Characterization of the structures of phosphodiesterase 10 binding with adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate by hybrid quantum mechanical/molecular mechanical calculations.

  The journal of physical chemistry. B 20100527

• Oxidative modification of guanine bases initiated by oxyl radicals derived from photolysis of azo compounds.

  The journal of physical chemistry. B 20100520

• Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148.

  Bioorganic & medicinal chemistry 20100515

• Complementary interactions of the rod PDE6 inhibitory subunit with the catalytic subunits and transducin.

  The Journal of biological chemistry 20100514

• Collision-induced dissociation (CID) of guanine radical cation in the gas phase: an experimental and computational study.

  Physical chemistry chemical physics : PCCP 20100514

• Triggering of guanosine self-assembly by light.

  Angewandte Chemie (International ed. in English) 20100510

• Differential fluorescence quenching of fluorescent nucleic acid base analogues by native nucleic acid monophosphates.

  The journal of physical chemistry. B 20100506

• A functional human Poly(A) site requires only a potent DSE and an A-rich upstream sequence.

  The EMBO journal 20100505

• Induction of type I interferon by RNA viruses: cellular receptors and their substrates.

  Amino acids 20100501

• Rapid cleavage of RNA by RNase E in the absence of 5' monophosphate stimulation.

  Molecular microbiology 20100501

• Quantitative determination of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine, 8-oxo-7,8-dihydroguanine, 8-oxo-7,8-dihydroguanosine, and their non-oxidized forms: daily concentration profile in healthy volunteers.

  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20100501

• The multiple actions of NO.

  Pflugers Archiv : European journal of physiology 20100501

• Effects of motilin on intracellular free calcium in cultured smooth muscle cells from the antrum of neonatal rats.

  Acta physiologica (Oxford, England) 20100501

• Impact of the DRY motif and the missing 'ionic lock' on constitutive activity and G-protein coupling of the human histamine H4 receptor.

  The Journal of pharmacology and experimental therapeutics 20100501

• Regulation of the autophagic machinery in human neutrophils.

  European journal of immunology 20100501

• Anti-inflammatory properties of CB1-receptor antagonist involves beta2 adrenoceptors.

  The Journal of pharmacology and experimental therapeutics 20100501

• Mycophenolic acid differentially affects dendritic cell maturation induced by tumor necrosis factor-alpha and lipopolysaccharide through a different modulation of MAPK signaling.

  Molecular immunology 20100501

• Synapse pathology in psychiatric and neurologic disease.

  Current neurology and neuroscience reports 20100501

• Characterization of oxidative guanine damage and repair in mammalian telomeres.

  PLoS genetics 20100501

• A survey of genomic traces reveals a common sequencing error, RNA editing, and DNA editing.

  PLoS genetics 20100501

• Changes in purines concentration in the cerebrospinal fluid of patients experiencing pain: a case-control study.

  Neuroscience letters 20100426

• Gi-protein inhibitor, guanosine 5'-O-(2-thiodiphosphate), induces senescence-associated beta-galactosidase positive cell formation through CREB phosphorylation.

  Life sciences 20100424

• Discovery and characterization of an amidinotransferase involved in the modification of archaeal tRNA.

  The Journal of biological chemistry 20100423

• Intramolecular movements in EF-G, trapped at different stages in its GTP hydrolytic cycle, probed by FRET.

  Journal of molecular biology 20100416

• Colorimetric biosensing of mercury(II) ion using unmodified gold nanoparticle probes and thrombin-binding aptamer.

  Biosensors & bioelectronics 20100415

• Postsynaptic density-93 deficiency protects cultured cortical neurons from N-methyl-D-aspartate receptor-triggered neurotoxicity.

  Neuroscience 20100414

• Polymeric structures and dynamic properties of the bacterial actin AlfA.

  Journal of molecular biology 20100409

• Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex.

  Journal of molecular biology 20100409

• Persistent, well-defined, monodisperse, pi-conjugated organic nanoparticles via G-quadruplex self-assembly.

  Journal of the American Chemical Society 20100407

• Gender- and age-dependent changes in nucleoside levels in the cerebral cortex and white matter of the human brain.

  Brain research bulletin 20100405

• Selective D1 agonism but not D2 antagonism is reflected in cAMP and cGMP levels in rat CSF.

  Brain research bulletin 20100405

• Inhibition of fatty-acid amide hydrolase and CB1 receptor antagonism differentially affect behavioural responses in normal and PCP-treated rats.

  The international journal of neuropsychopharmacology 20100401

• Regulation of cortical and hippocampal 5-HT(1A) receptor function by corticosterone in GR+/- mice.

  Psychoneuroendocrinology 20100401

• Antiviral efficacy of EICAR against canine distemper virus (CDV) in vitro.

  Research in veterinary science 20100401

• Combined radionuclide-chemotherapy and in vivo imaging of hepatocellular carcinoma cells after transfection of a triple-gene construct, NIS, HSV1-sr39tk, and EGFP.

  Cancer letters 20100401

• Identification of a novel 'almost neutral' micro-opioid receptor antagonist in CHO cells expressing the cloned human mu-opioid receptor.

  Synapse (New York, N.Y.) 20100401

• In vitro and in vivo pharmacological characterization of two novel selective cannabinoid CB(2) receptor inverse agonists.

  Pharmacological research 20100401

• Increased CYP2J3 expression reduces insulin resistance in fructose-treated rats and db/db mice.

  Diabetes 20100401

• Sigma 1 receptor modulation of G-protein-coupled receptor signaling: potentiation of opioid transduction independent from receptor binding.

  Molecular pharmacology 20100401

• Adenosine inhibits paraventricular pre-sympathetic neurons through ATP-dependent potassium channels.

  Journal of neurochemistry 20100401

• Subcellular localization of mu-opioid receptor G(s) signaling.

  The Journal of pharmacology and experimental therapeutics 20100401

• Genome-wide screening of genes whose enhanced expression affects glycogen accumulation in Escherichia coli.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20100401

• eNOS plays a major role in adiponectin synthesis in adipocytes.

  American journal of physiology. Endocrinology and metabolism 20100401

• Vital role of protein kinase C-related kinase in the formation and stability of neurites during hypoxia.

  Journal of neurochemistry 20100401

• Paradoxical relationship between RAVE (relative activity versus endocytosis) values of several opioid receptor agonists and their liability to cause dependence.

  Acta pharmacologica Sinica 20100401

• Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance.

  The Journal of clinical investigation 20100401

• LyGDI is a promising biomarker for ovarian cancer.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20100401

• Structural basis for Fe-S cluster assembly and tRNA thiolation mediated by IscS protein-protein interactions.

  PLoS biology 20100401

• [Human lung cancer: role of TLR7 and TLR8 in cell survival and chemoresistance].

  Medecine sciences : M/S 20100401

• In vitro reconstitution of SARS-coronavirus mRNA cap methylation.

  PLoS pathogens 20100401

• [Studies on photoinduced electron and proton transfer reactions of nucleic acid and aromatic ketone].

  Guang pu xue yu guang pu fen xi = Guang pu 20100401

• Toxins-useful biochemical tools for leukocyte research.

  Toxins 20100401

• A rearrangement of the guanosine-binding site establishes an extended network of functional interactions in the Tetrahymena group I ribozyme active site.

  Biochemistry 20100330

• Opioid-induced long-term potentiation in the spinal cord is a presynaptic event.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100324

• Flexible recognition of the tRNA G18 methylation target site by TrmH methyltransferase through first binding and induced fit processes.

  The Journal of biological chemistry 20100319

• The proline-rich N-terminal domain of G18 exhibits a novel G protein regulatory function.

  The Journal of biological chemistry 20100319

• NSF independent fusion of Salmonella-containing late phagosomes with early endosomes.

  FEBS letters 20100319

• Comparative biochemical and pharmacological characterization of a novel, NOP receptor selective hexapeptide, Ac-RYYRIR-ol.

  Brain research bulletin 20100316

• 8-Hydroxydeoxyguanosine: a new potential independent prognostic factor in breast cancer.

  British journal of cancer 20100316

• DNA polymerases as potential therapeutic targets for cancers deficient in the DNA mismatch repair proteins MSH2 or MLH1.

  Cancer cell 20100316

• Exon array analyses across the NCI-60 reveal potential regulation of TOP1 by transcription pausing at guanosine quartets in the first intron.

  Cancer research 20100315

• G proteins in reverse mode: receptor-mediated GTP release inhibits G protein and effector function.

  The Journal of biological chemistry 20100312

• Discovery of 4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)ethyl)piperazin-1-yl)quinolin-8-ol and its analogues as highly potent dopamine D2/D3 agonists and as iron chelator: in vivo activity indicates potential application in symptomatic and neuroprotective therapy for Parkinson's disease.

  Journal of medicinal chemistry 20100311

• Mutagenic potential of DNA glycation: miscoding by (R)- and (S)-N2-(1-carboxyethyl)-2'-deoxyguanosine.

  Biochemistry 20100309

• Identification of orthosteric and allosteric site mutations in M2 muscarinic acetylcholine receptors that contribute to ligand-selective signaling bias.

  The Journal of biological chemistry 20100305

• Preparation of the 2'-deoxynucleosides of 2,6-diaminopurine and isoguanine by direct glycosylation.

  The Journal of organic chemistry 20100305

• Mutation versus repair: NEIL1 removal of hydantoin lesions in single-stranded, bulge, bubble, and duplex DNA contexts.

  Biochemistry 20100302

• Effect of ribavirin on the frequency of RNase L cleavage sites within the hepatitis C viral genome.

  Journal of viral hepatitis 20100301

• Nucleoside map of the human central nervous system.

  Neurochemical research 20100301

• Molecular mechanisms of action and in vivo validation of an M4 muscarinic acetylcholine receptor allosteric modulator with potential antipsychotic properties.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100301

• Chuanxiongzine relaxes isolated corpus cavernosum strips and raises intracavernous pressure in rabbits.

  International journal of impotence research 20100301

• Mechanisms of copy number variation and hybrid gene formation in the KIR immune gene complex.

  Human molecular genetics 20100301

• Phosphorylation of the mu-opioid receptor at tyrosine 166 (Tyr3.51) in the DRY motif reduces agonist efficacy.

  Molecular pharmacology 20100301

• Long-term fluoxetine treatment modulates cannabinoid type 1 receptor-mediated inhibition of adenylyl cyclase in the rat prefrontal cortex through 5-hydroxytryptamine 1A receptor-dependent mechanisms.

  Molecular pharmacology 20100301

• Hyperglycemia impairs proteasome function by methylglyoxal.

  Diabetes 20100301

• Lead identification and optimization of diaminopyrimidines as histamine H4 receptor ligands.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100301

• UR-60427, a novel H4 receptor-inverse agonist that shows good efficacy in a rat asthma model.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100301

• Central and peripheral consequences of the chronic blockade of CB1 cannabinoid receptor with rimonabant or taranabant.

  Journal of neurochemistry 20100301

• Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease.

  Neurobiology of disease 20100301

• Cloning, purification and characterisation of a recombinant purine nucleoside phosphorylase from Bacillus halodurans Alk36.

  Extremophiles : life under extreme conditions 20100301

• Hepatitis C virus induces oxidative stress, DNA damage and modulates the DNA repair enzyme NEIL1.

  Journal of gastroenterology and hepatology 20100301

• Homogeneous GTP binding assay employing QRET technology.

  Journal of biomolecular screening 20100301

• Gibberellic acid and cGMP-dependent transcriptional regulation in Arabidopsis thaliana.

  Plant signaling & behavior 20100301

• Mechanisms involved in the antinociception induced by systemic administration of guanosine in mice.

  British journal of pharmacology 20100301

• Binding of GTPgamma[35S] is regulated by GDP and receptor activation. Studies with the nociceptin/orphanin FQ receptor.

  British journal of pharmacology 20100301

• Multiple receptor tyrosine kinases are expressed in adult rat retinal ganglion cells as revealed by single-cell degenerate primer polymerase chain reaction.

  Upsala journal of medical sciences 20100301

• Synthesis and properties of diazirinyl organo-platinum compounds for manipulations of photoaffinity labeled components.

  Chemical & pharmaceutical bulletin 20100301

• G-less cassette in vitro transcription using HeLa cell nuclear extracts.

  Cold Spring Harbor protocols 20100301

• Role of RecA and the SOS response in thymineless death in Escherichia coli.

  PLoS genetics 20100301

• Urinary 8-hydroxydeoxyguanosine levels and psychological reactions after sleep deprivation.

  Journal of UOEH 20100301

• YfiBNR mediates cyclic di-GMP dependent small colony variant formation and persistence in Pseudomonas aeruginosa.

  PLoS pathogens 20100301

• Cholera toxin: an intracellular journey into the cytosol by way of the endoplasmic reticulum.

  Toxins 20100301

• Role of transmembrane domain 4 in ligand permeation by Crithidia fasciculata equilibrative nucleoside transporter 2 (CfNT2).

  The Journal of biological chemistry 20100226

• Solvent-induced switching between two supramolecular assemblies of a guanosine-terthiophene conjugate.

  Organic & biomolecular chemistry 20100221

• Europium-labeled GTP as a general nonradioactive substitute for [(35)S]GTPgammaS in high-throughput G protein studies.

  Analytical biochemistry 20100215

• Influence of substrate complexity on the diastereoselective formation of spiroiminodihydantoin and guanidinohydantoin from chromate oxidation.

  Chemical research in toxicology 20100215

• Protein-precursor tRNA contact leads to sequence-specific recognition of 5' leaders by bacterial ribonuclease P.

  Journal of molecular biology 20100212

• Development of (S)-N6-(2-(4-(isoquinolin-1-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine and its analogue as a D3 receptor preferring agonist: potent in vivo activity in Parkinson's disease animal models.

  Journal of medicinal chemistry 20100211

• Synthesis of dihydrofuroaporphine derivatives: identification of a potent and selective serotonin 5-HT 1A receptor agonist.

  Journal of medicinal chemistry 20100211

• Synthesis and opioid activity of enantiomeric N-substituted 2,3,4,4a,5,6,7,7a-octahydro-1H-benzofuro[3,2-e]isoquinolines.

  Journal of medicinal chemistry 20100211

• Supramolecular ABC triblock copolymers via one-pot, orthogonal self-assembly.

  Journal of the American Chemical Society 20100210

• Synthesis and crystal structure of 2'-se-modified guanosine containing DNA.

  The Journal of organic chemistry 20100205

• A stable G-quartet binds to a huntingtin protein fragment containing expanded polyglutamine tracks.

  Journal of neuroscience research 20100201

• Guanosine prevents thermal hyperalgesia in a rat model of peripheral mononeuropathy.

  The journal of pain : official journal of the American Pain Society 20100201

• The synthesis and function of the alarmone (p)ppGpp in firmicutes.

  International journal of medical microbiology : IJMM 20100201

• Detection of DNA damage in fish Oreochromis mossambicus induced by co-exposure to phenanthrene and nitrite by ESI-MS/MS.

  Environmental science and pollution research international 20100201

• The roles of the dystrophin-associated glycoprotein complex at the synapse.

  Molecular neurobiology 20100201

• A bulky platinum triamine complex that reacts faster with guanosine 5'-monophosphate than with N-acetylmethionine.

  Journal of inorganic biochemistry 20100201

• Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo.

  The Journal of pharmacology and experimental therapeutics 20100201

• Amoxapine inhibits the delayed rectifier outward K+ current in mouse cortical neurons via cAMP/protein kinase A pathways.

  The Journal of pharmacology and experimental therapeutics 20100201

• Effects of some modulators on purine nucleoside phosphorylase activity in myocardial tissue.

  Scandinavian journal of clinical and laboratory investigation 20100201

• Electrophysiological effects of guanosine and MK-801 in a quinolinic acid-induced seizure model.

  Experimental neurology 20100201

• Differential modulation of mu-opioid receptor signaling to adenylyl cyclase by regulators of G protein signaling proteins 4 or 8 and 7 in permeabilised C6 cells is Galpha subtype dependent.

  Journal of neurochemistry 20100201

• Elongation factors are involved in cytokinesis of sea urchin eggs.

  Genes to cells : devoted to molecular & cellular mechanisms 20100201

• Origin of highly pathogenic porcine reproductive and respiratory syndrome virus, China.

  Emerging infectious diseases 20100201

• A new nuclear function of the Entamoeba histolytica glycolytic enzyme enolase: the metabolic regulation of cytosine-5 methyltransferase 2 (Dnmt2) activity.

  PLoS pathogens 20100201

• Neoadjuvant immunotherapy enhances radiosensitivity through natural killer cell activation.

  Cancer biotherapy & radiopharmaceuticals 20100201

• Mouse strain differences in locomotor, sensitisation and rewarding effect of heroin; association with alterations in MOP-r activation and dopamine transporter binding.

  The European journal of neuroscience 20100201

• [Molecular cloning, gene expression and characterization of purine nucleoside phosphorylase from Pseudoalteromonas sp. XM2107].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20100201

• [Study on influence of arbuscular mycorrhizal fungi Pinellia ternata yield and chemical composition].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100201

• Effect of propofol on cardiac function and gene expression after ischemic-reperfusion in isolated rat heart.

  Korean journal of anesthesiology 20100201

• Expression and contribution of satellite glial cells purinoceptors to pain transmission in sensory ganglia: an update.

  Neuron glia biology 20100201

• Ribonucleoside labeling with Os(VI): a methodological approach to evaluation of RNA methylation by HPLC-ICP-MS.

  Metallomics : integrated biometal science 20100201

• Pathological basis of symptoms and crises in sickle cell disorder: implications for counseling and psychotherapy.

  Hematology reports 20100126

• Comprehensive analysis of DNA strand breaks at the guanosine site induced by low-energy electron attachment.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20100118

• Sensing purine nucleoside phosphorylase activity by using silver nanoparticles.

  Biosensors & bioelectronics 20100115

• Crystal structure of the ATPPase subunit and its substrate-dependent association with the GATase subunit: a novel regulatory mechanism for a two-subunit-type GMP synthetase from Pyrococcus horikoshii OT3.

  Journal of molecular biology 20100115

• Regulation of mRNA cap methylation.

  The Biochemical journal 20100115

• Solution structure of a unique G-quadruplex scaffold adopted by a guanosine-rich human intronic sequence.

  Structure (London, England : 1993) 20100113

• Study of phase transformation of guanosine 5'-monophosphate in drowning-out crystallization.

  Applied biochemistry and biotechnology 20100101

• Isotope labeling strategies for NMR studies of RNA.

  Journal of biomolecular NMR 20100101

• Direct agonist activity of tricyclic antidepressants at distinct opioid receptor subtypes.

  The Journal of pharmacology and experimental therapeutics 20100101

• Activity-mediated plasticity of GABA equilibrium potential in rat hippocampal CA1 neurons.

  Experimental neurology 20100101

• Monocyclic aromatic amines as potential human carcinogens: old is new again.

  Carcinogenesis 20100101

• Endogenous glucagon-like peptide-1 slows gastric emptying in healthy subjects, attenuating postprandial glycemia.

  The Journal of clinical endocrinology and metabolism 20100101

• Cap analog substrates reveal three clades of cap guanine-N2 methyltransferases with distinct methyl acceptor specificities.

  RNA (New York, N.Y.) 20100101

• Photophysics and photochemical studies of the vitamin B6 group and related derivatives.

  Photochemistry and photobiology 20100101

• Pumilio 2 controls translation by competing with eIF4E for 7-methyl guanosine cap recognition.

  RNA (New York, N.Y.) 20100101

• Facile and efficient approach for the synthesis of N(2)-dimethylaminomethylene-2'-O-methylguanosine.

  Bioorganic & medicinal chemistry letters 20100101

• Genetically engineered Salmonella typhimurium as an imageable therapeutic probe for cancer.

  Cancer research 20100101

• Intrinsic cellular defenses against virus infection by antiviral type I interferon.

  Yonsei medical journal 20100101

• A computational screen for site selective A-to-I editing detects novel sites in neuron specific Hu proteins.

  BMC bioinformatics 20100101

• Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni.

  Acta crystallographica. Section D, Biological crystallography 20100101

• Genetic analysis of the Staphylococcus epidermidis macromolecular synthesis operon: Serp1129 is an ATP binding protein and sigA transcription is regulated by both sigma(A)- and sigma(B)-dependent promoters.

  BMC microbiology 20100101

• Differentiation of intestinal epithelial cells mediated by cell confluence and/or exogenous nucleoside supplementation.

  Cells, tissues, organs 20100101

• Innovative agents for actinic keratosis and nanocarriers enhancing skin penetration.

  Skin pharmacology and physiology 20100101

• Expression profiles during dedifferentiation in newt lens regeneration revealed by expressed sequence tags.

  Molecular vision 20100101

• A new paradigm for antimicrobial host defense mediated by a nitrated cyclic nucleotide.

  Journal of clinical biochemistry and nutrition 20100101

• Targeting viral infection by microRNA inhibition.

  Genome biology 20100101

• The mitochondrial genome of the entomoparasitic green alga helicosporidium.

  PloS one 20100101

• Alternative splicing and extensive RNA editing of human TPH2 transcripts.

  PloS one 20100101

• The Mrs1 splicing factor binds the bI3 group I intron at each of two tetraloop-receptor motifs.

  PloS one 20100101

• The Arabidopsis wall associated kinase-like 10 gene encodes a functional guanylyl cyclase and is co-expressed with pathogen defense related genes.

  PloS one 20100101

• Alpha-1,2-mannosidase and hence N-glycosylation are required for regulatory T cell migration and allograft tolerance in mice.

  PloS one 20100101

• Molecular modulation of intestinal epithelial barrier: contribution of microbiota.

  Journal of biomedicine & biotechnology 20100101

• Expression and functional activity of nucleoside transporters in human choroid plexus.

  Cerebrospinal fluid research 20100101

• Temporal ChIP-on-Chip of RNA-Polymerase-II to detect novel gene activation events during photoreceptor maturation.

  Molecular vision 20100101

• Cloning, purification, and partial characterization of Bacillus subtilis urate oxidase expressed in Escherichia coli.

  Journal of biomedicine & biotechnology 20100101

• Alterations in adenosine metabolism and signaling in patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis.

  PloS one 20100101

• Shorter GT repeat polymorphism in the heme oxygenase-1 gene promoter has protective effect on ischemic stroke in dyslipidemia patients.

  Journal of biomedical science 20100101

• Signal transduction, receptors, mediators and genes: younger than ever - the 13th meeting of the Signal Transduction Society focused on aging and immunology.

  Cell communication and signaling : CCS 20100101

• Molecular characterisation of virulence graded field isolates of myxoma virus.

  Virology journal 20100101

• Quality evaluation of mycelial Antrodia camphorata using high-performance liquid chromatography (HPLC) coupled with diode array detector and mass spectrometry (DAD-MS).

  Chinese medicine 20100101

• Homeostatic imbalance of purine catabolism in first-episode neuroleptic-naïve patients with schizophrenia.

  PloS one 20100101

• The PPARbeta/delta agonist GW0742 relaxes pulmonary vessels and limits right heart hypertrophy in rats with hypoxia-induced pulmonary hypertension.

  PloS one 20100101

• Modulation by neuropeptide FF of the interaction of mu-opioid (MOP) receptor with G-proteins.

  Neurochemistry international 20100101

• Depletion of the non-coding regulatory 6S RNA in E. coli causes a surprising reduction in the expression of the translation machinery.

  BMC genomics 20100101

• Investigating a new generation of ribozymes in order to target HCV.

  PloS one 20100101

• Modern role for clopidogrel in management of atrial fibrillation and stroke reduction.

  Vascular health and risk management 20100101

• Production of recombinant proteins in E. coli by the heat inducible expression system based on the phage lambda pL and/or pR promoters.

  Microbial cell factories 20100101

• A plant natriuretic peptide-like molecule of the pathogen Xanthomonas axonopodis pv. citri causes rapid changes in the proteome of its citrus host.

  BMC plant biology 20100101

• Opposite changes in cannabinoid CB1 and CB2 receptor expression in human gliomas.

  Neurochemistry international 20100101

• Expression and aberrant promoter methylation of Wnt inhibitory factor-1 in human astrocytomas.

  Journal of experimental & clinical cancer research : CR 20100101

• Novel approaches to treat experimental pulmonary arterial hypertension: a review.

  Journal of biomedicine & biotechnology 20100101

• [Simultaneous determination of five nucleotides in Bulbus Fritillariae by RP-HPLC].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100101

• CXCR4 mediated chemotaxis is regulated by 5T4 oncofetal glycoprotein in mouse embryonic cells.

  PloS one 20100101

• Guanosine-induced decrease in side population of lung cancer cells: lack of correlation with ABCG2 expression.

  Journal of biological regulators and homeostatic agents 20100101

• Natural occurrence of 2',5'-linked heteronucleotides in marine sponges.

  Marine drugs 20100101

• Pattern recognition via the toll-like receptor system in the human female genital tract.

  Mediators of inflammation 20100101

• A comprehensive molecular interaction map for rheumatoid arthritis.

  PloS one 20100101

• Up-regulation of avian uncoupling protein in cold-acclimated and hyperthyroid ducklings prevents reactive oxygen species production by skeletal muscle mitochondria.

  BMC physiology 20100101

• Thrombospondin-1 null mice are resistant to hypoxia-induced pulmonary hypertension.

  Journal of cardiothoracic surgery 20100101

• The diagnostic value of endothelial function as a potential sensor of fatigue in health.

  Vascular health and risk management 20100101

• Advances in the treatment of Raynaud's phenomenon.

  Vascular health and risk management 20100101

• Is Lamarckian evolution relevant to medicine?

  BMC medical genetics 20100101

• Alterations in early cytokine-mediated immune responses to Plasmodium falciparum infection in Tanzanian children with mineral element deficiencies: a cross-sectional survey.

  Malaria journal 20100101

• Polyfunctional CD4+ T cell responses to a set of pathogenic arenaviruses provide broad population coverage.

  Immunome research 20100101

• [The clinical diagnostic value of a study of the activity of enzymes of the guanyl branch of purine metabolism in patients with ankylosing spondyloarthritis].

  Terapevticheskii arkhiv 20100101

• Effective inhibition of HCMV UL49 gene expression and viral replication by oligonucleotide external guide sequences and RNase P.

  Virology journal 20100101

• A human functional protein interaction network and its application to cancer data analysis.

  Genome biology 20100101

• Beneficial effects of a Q-ter based nutritional mixture on functional performance, mitochondrial function, and oxidative stress in rats.

  PloS one 20100101

• Adenosine thiamine triphosphate accumulates in Escherichia coli cells in response to specific conditions of metabolic stress.

  BMC microbiology 20100101

• Signal transduction mechanisms involved in S100A4-induced activation of the transcription factor NF-kappaB.

  BMC cancer 20100101

• Role of heme oxygenase in inflammation, insulin-signalling, diabetes and obesity.

  Mediators of inflammation 20100101

• From biological gastroenterology to fundamental neurosciences: how studies in gastric emptying have led to the discovery of a new mechanism of neuronal functioning.

  Gastroenterologie clinique et biologique 20100101

• Comparison of antiviral activity of recombinant and natural interferons against crimean-congo hemorrhagic Fever virus.

  The open virology journal 20100101

• Sex differences in dopamine D2-like receptor-mediated G-protein activation in the medial prefrontal cortex after cocaine.

  Ethnicity & disease 20100101

• RS-1748, a novel CC chemokine receptor 4 antagonist, inhibits ovalbumin-induced airway inflammation in guinea pigs.

  Biological & pharmaceutical bulletin 20100101

• Update on the clinical utility of sildenafil in the treatment of pulmonary arterial hypertension.

  Drug design, development and therapy 20100101

• Transdermal nitroglycerine enhances postoperative analgesia of intrathecal neostigmine following abdominal hysterectomies.

  Indian journal of anaesthesia 20100101

• Structural and dynamical effects induced by the anticancer drug topotecan on the human topoisomerase I - DNA complex.

  PloS one 20100101

• Q344ter mutation causes mislocalization of rhodopsin molecules that are catalytically active: a mouse model of Q344ter-induced retinal degeneration.

  PloS one 20100101

• Extracellular ATP and the P2X7 receptor in astrocyte-mediated motor neuron death: implications for amyotrophic lateral sclerosis.

  Journal of neuroinflammation 20100101

• Innate immune recognition and activation during HIV infection.

  Retrovirology 20100101

• Detection and analysis of alternative splicing in Yarrowia lipolytica reveal structural constraints facilitating nonsense-mediated decay of intron-retaining transcripts.

  Genome biology 20100101

• High-affinity consensus binding of target RNAs by the STAR/GSG proteins GLD-1, STAR-2 and Quaking.

  BMC molecular biology 20100101

• Alu sequences in undifferentiated human embryonic stem cells display high levels of A-to-I RNA editing.

  PloS one 20100101

• Study of the nitric oxide system in the rat cerebellum during aging.

  BMC neuroscience 20100101

• Impact of RNA editing on functions of the serotonin 2C receptor in vivo.

  Frontiers in neuroscience 20100101

• Cell type mediated resistance of vesicular stomatitis virus and Sendai virus to ribavirin.

  PloS one 20100101

• Live recombinant Salmonella Typhi vaccines constructed to investigate the role of rpoS in eliciting immunity to a heterologous antigen.

  PloS one 20100101

• Subcutaneous Sarcoidosis during Pegylated Interferon Alfa and Ribavirin Treatment for Chronic Hepatitis C.

  Dermatology research and practice 20100101

• N-methyl-aspartate receptor and neuronal nitric oxide synthase activation mediate bilirubin-induced neurotoxicity.

  Molecular medicine (Cambridge, Mass.) 20100101

• [Continuing investigation of effect of toner and its by-product on human health and occupational health management of toner].

  Sangyo eiseigaku zasshi = Journal of occupational health 20100101

• RNA vaccines in cancer treatment.

  Journal of biomedicine & biotechnology 20100101

• A liquid chromatographic method for routine analysis of 5'-mononucleotides in pediatric formulas.

  Journal of AOAC International 20100101

• Endothelial dysfunction, inflammation, and apoptosis in diabetes mellitus.

  Mediators of inflammation 20100101

• PAR-CliP--a method to identify transcriptome-wide the binding sites of RNA binding proteins.

  Journal of visualized experiments : JoVE 20100101

• Complete mitochondrial genomes of Taenia multiceps, T. hydatigena and T. pisiformis: additional molecular markers for a tapeworm genus of human and animal health significance.

  BMC genomics 20100101

• Adipocytokines in atherothrombosis: focus on platelets and vascular smooth muscle cells.

  Mediators of inflammation 20100101

• Identification of pathway-biased and deleterious melatonin receptor mutants in autism spectrum disorders and in the general population.

  PloS one 20100101

• Large-scale analysis of structural, sequence and thermodynamic characteristics of A-to-I RNA editing sites in human Alu repeats.

  BMC genomics 20100101

• Effects of GCK, GCKR, G6PC2 and MTNR1B variants on glucose metabolism and insulin secretion.

  PloS one 20100101

• Immunomodulatory effects of dsRNA and its potential as vaccine adjuvant.

  Journal of biomedicine & biotechnology 20100101

• Archaea signal recognition particle shows the way.

  Archaea (Vancouver, B.C.) 20100101

• Oscillations by minimal bacterial suicide circuits reveal hidden facets of host-circuit physiology.

  PloS one 20100101

• Methylated APC and GSTP1 genes in serum DNA correlate with the presence of circulating blood tumor cells and are associated with a more aggressive and advanced breast cancer disease.

  European journal of medical research 20100101

• Candida albicans AGE3, the ortholog of the S. cerevisiae ARF-GAP-encoding gene GCS1, is required for hyphal growth and drug resistance.

  PloS one 20100101

• Long-Term Impact of Cyclosporin Reduction with MMF Treatment in Chronic Allograft Dysfunction: REFERENECE Study 3-Year Follow Up.

  Journal of transplantation 20100101

• Effect of base sequence on g-wire formation in solution.

  Journal of nucleic acids 20100101

• Guanosine quadruplexes in solution: a small-angle x-ray scattering analysis of temperature effects on self-assembling of deoxyguanosine monophosphate.

  Journal of nucleic acids 20100101

• A toolbox for predicting g-quadruplex formation and stability.

  Journal of nucleic acids 20100101

• Specificity of methylation assays in cancer research: a guideline for designing primers and probes.

  Obstetrics and gynecology international 20100101

• Integrating GHS into the Ghrelin System.

  International journal of peptides 20100101

• Hierarchical formation of fibrillar and lamellar self-assemblies from guanosine-based motifs.

  Journal of nucleic acids 20100101

• Protection effect of taurine on nitrosative stress in the mice brain with chronic exposure to arsenic.

  Journal of biomedical science 20100101

• Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis.

  BMC systems biology 20100101

• Spatial regulation of membrane fusion controlled by modification of phosphoinositides.

  PloS one 20100101

• Overexpression of inosine 5'-monophosphate dehydrogenase type II mediates chemoresistance to human osteosarcoma cells.

  PloS one 20100101

• Template-directed ligation of tethered mononucleotides by t4 DNA ligase for kinase ribozyme selection.

  PloS one 20100101

• Cytidine-Ag+-purine base complexes as studied by electrospray ionization mass spectrometry.

  European journal of mass spectrometry (Chichester, England) 20100101

• G-quadruplex nucleic acids.

  Journal of nucleic acids 20100101

• Epigenetics of renal cell carcinoma: the path towards new diagnostics and therapeutics.

  Genome medicine 20100101

• The genome of Geobacter bemidjiensis, exemplar for the subsurface clade of Geobacter species that predominate in Fe(III)-reducing subsurface environments.

  BMC genomics 20100101

• Transfer RNA modifications and genes for modifying enzymes in Arabidopsis thaliana.

  BMC plant biology 20100101

• Guanosine protects human neuroblastoma cells from oxidative stress and toxicity induced by Amyloid-beta peptide oligomers.

  Journal of biological regulators and homeostatic agents 20100101

• Selenocysteine, pyrrolysine, and the unique energy metabolism of methanogenic archaea.

  Archaea (Vancouver, B.C.) 20100101

• Toll-like receptors: role in dermatological disease.

  Mediators of inflammation 20100101

• MPF governs the assembly and contraction of actomyosin rings by activating RhoA and MAPK during chemical-induced cytokinesis of goat oocytes.

  PloS one 20100101

• Pulmonary vascular and right ventricular dysfunction in adult critical care: current and emerging options for management: a systematic literature review.

  Critical care (London, England) 20100101

• Crystal structure of the dengue virus methyltransferase bound to a 5'-capped octameric RNA.

  PloS one 20100101

• Early combined treatment with sildenafil and adipose-derived mesenchymal stem cells preserves heart function in rat dilated cardiomyopathy.

  Journal of translational medicine 20100101

• Gut inflammation in chronic fatigue syndrome.

  Nutrition & metabolism 20100101

• Can physical stress be measured in urine using the parameter antioxidative potential?

  GMS Krankenhaushygiene interdisziplinar 20100101

• Comparison of selected cryoprotective agents to stabilize meiotic spindles of human oocytes during cooling.

  Journal of experimental & clinical assisted reproduction 20100101

• Recent advances in management of bladder overactivity.

  F1000 medicine reports 20100101

• Consistent levels of A-to-I RNA editing across individuals in coding sequences and non-conserved Alu repeats.

  BMC genomics 20100101

• Effects of mycophenolate mofetil on proliferation and mucin-5AC expression in human conjunctival goblet cells in vitro.

  Molecular vision 20100101

• Detecting constitutive activity and protean agonism at cannabinoid-2 receptor.

  Methods in enzymology 20100101

• Constitutive activity of GPR40/FFA1 intrinsic or assay dependent?

  Methods in enzymology 20100101

• Analysis of Monosodium l-Glutamate in Food Products by High-Performance Thin Layer Chromatography.

  Journal of young pharmacists : JYP 20100101

• Measurement of inverse agonism of the cannabinoid receptors.

  Methods in enzymology 20100101

• Methods to measure g-protein-coupled receptor activity for the identification of inverse agonists.

  Methods in enzymology 20100101

• Fusion proteins as model systems for the analysis of constitutive GPCR activity.

  Methods in enzymology 20100101

• Coexpression systems as models for the analysis of constitutive GPCR activity.

  Methods in enzymology 20100101

• Effects of inosine on reperfusion injury after cardiopulmonary bypass.

  Journal of cardiothoracic surgery 20100101

• Substitutional A-to-I RNA editing.

  Wiley interdisciplinary reviews. RNA 20100101

• Inhibition of core gene of HCV 3a genotype using synthetic and vector derived siRNAs.

  Virology journal 20100101

• RhoA regulates peroxisome association to microtubules and the actin cytoskeleton.

  PloS one 20100101

• Zinc in innate and adaptive tumor immunity.

  Journal of translational medicine 20100101

• An empirical Bayes model for gene expression and methylation profiles in antiestrogen resistant breast cancer.

  BMC medical genomics 20100101

• Differential proteomic analysis highlights metabolic strategies associated with balhimycin production in Amycolatopsis balhimycina chemostat cultivations.

  Microbial cell factories 20100101

• PARP1 gene knock-out increases resistance to retinal degeneration without affecting retinal function.

  PloS one 20100101

• Neuroprotective properties of mildronate, a small molecule, in a rat model of Parkinson's disease.

  International journal of molecular sciences 20100101

• Identification, activity and disulfide connectivity of C-di-GMP regulating proteins in Mycobacterium tuberculosis.

  PloS one 20100101

• The N-terminus of GalE induces tmRNA activity in Escherichia coli.

  PloS one 20100101

• Expression and regulation of cyclic nucleotide phosphodiesterases in human and rat pancreatic islets.

  PloS one 20100101

• Clinical effectiveness of telmisartan alone or in combination therapy for controlling blood pressure and vascular risk in the elderly.

  Clinical interventions in aging 20100101

• Mechanistic and functional versatility of radical SAM enzymes.

  F1000 biology reports 20100101

• Comparative proteomic analysis of Salmonella enterica serovar Typhimurium ppGpp-deficient mutant to identify a novel virulence protein required for intracellular survival in macrophages.

  BMC microbiology 20100101

• Caffeine's Vascular Mechanisms of Action.

  International journal of vascular medicine 20100101

• Amyloid-β inhibits No-cGMP signaling in a CD36- and CD47-dependent manner.

  PloS one 20100101

• The biological and metabolic fates of endogenous DNA damage products.

  Journal of nucleic acids 20100101

• Formation and repair of tobacco carcinogen-derived bulky DNA adducts.

  Journal of nucleic acids 20100101

• Towards a systems approach in the genetic analysis of archaea: Accelerating mutant construction and phenotypic analysis in Haloferax volcanii.

  Archaea (Vancouver, B.C.) 20100101

• Recent advancements in toxin and antitoxin systems involved in bacterial programmed cell death.

  International journal of microbiology 20100101

• Experimental models of duchenne muscular dystrophy: relationship with cardiovascular disease.

  The open cardiovascular medicine journal 20100101

• Insights into the development and treatment of cardiovascular disease: a role for animal models.

  The open cardiovascular medicine journal 20100101

• Glycoxidative stress and cardiovascular complications in experimentally-induced diabetes: effects of antioxidant treatment.

  The open cardiovascular medicine journal 20100101

• Mammalian target of rapamycin: hitting the bull's-eye for neurological disorders.

  Oxidative medicine and cellular longevity 20100101

• A rapid, inexpensive high throughput screen method for neurite outgrowth.

  Current chemical genomics 20100101

• Platelets and cardiac arrhythmia.

  Frontiers in physiology 20100101

• The NO-cGMP-PKG signaling pathway coordinately regulates ERK and ERK-driven gene expression at pre- and postsynaptic sites following LTP-inducing stimulation of thalamo-amygdala synapses.

  Neural plasticity 20100101

• An assay for measuring the activity of Escherichia coli inducible lysine decarboxylase.

  Journal of visualized experiments : JoVE 20100101

• Dendritic spines and development: towards a unifying model of spinogenesis--a present day review of Cajal's histological slides and drawings.

  Neural plasticity 20100101

• Are antioxidants helpful for disease prevention?

  Research in pharmaceutical sciences 20100101

• Screening and initial binding assessment of fumonisin b(1) aptamers.

  International journal of molecular sciences 20100101

• GIMAP Proteins in T-Lymphocytes.

  Journal of signal transduction 20100101

• Two phosphodiesterases from ustilago maydis share structural and biochemical properties with non-fungal phosphodiesterases.

  Frontiers in microbiology 20100101

• Role of tacrolimus combination therapy with mycophenolate mofetil in the prevention of organ rejection in kidney transplant patients.

  International journal of nephrology and renovascular disease 20100101

• Safety and tolerability of zoledronic acid and other bisphosphonates in osteoporosis management.

  Drug, healthcare and patient safety 20100101

• Design strategies of fluorescent biosensors based on biological macromolecular receptors.

  Sensors (Basel, Switzerland) 20100101

• The comparative efficacy and safety of peginterferon alpha-2a vs. 2b for the treatment of chronic HCV infection: a meta-analysis.

  Hepatitis monthly 20100101

• Interferon-alpha induced and ribavirin induced thyroid dysfunction in patients with chronic hepatitis C.

  Hepatitis monthly 20100101

• Oxidant sensing by protein kinases a and g enables integration of cell redox state with phosphoregulation.

  Sensors (Basel, Switzerland) 20100101

• Classification of g-quadruplex DNA on the basis of the quadruplex twist angle and planarity of g-quartets.

  Acta naturae 20100101

• Solvent effects on ionization potentials of guanine runs and chemically modified guanine in duplex DNA: effect of electrostatic interaction and its reduction due to solvent.

  The journal of physical chemistry. B 20091224

• Ultrashort fluorescence lifetimes of hydrogen-bonded base pairs of guanosine and cytidine in solution.

  The journal of physical chemistry. B 20091224

• Modulating unimolecular charge transfer by exciting bridge vibrations.

  Journal of the American Chemical Society 20091223

• Adenosine deamination in human transcripts generates novel microRNA binding sites.

  Human molecular genetics 20091215

• Functional characterization of intracellular Dictyostelium discoideum P2X receptors.

  The Journal of biological chemistry 20091211

• The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.

  Cell 20091211

• Synthesis and optical properties of guanosine 5'-monophosphate-mediated CdS nanostructures: an analysis of their structure, morphology, and electronic properties.

  Inorganic chemistry 20091207

• A recombination hot spot in HIV-1 contains guanosine runs that can form a G-quartet structure and promote strand transfer in vitro.

  The Journal of biological chemistry 20091204

• Kidney disease in nail-patella syndrome.

  Pediatric nephrology (Berlin, Germany) 20091201

• Influence of tunable external stimuli on the self-assembly of guanosine supramolecular nanostructures studied by atomic force microscope.

  Langmuir : the ACS journal of surfaces and colloids 20091201

• Resistance patterns and detection of aac(3)-IV gene in apramycin-resistant Escherichia coli isolated from farm animals and farm workers in northeastern of China.

  Research in veterinary science 20091201

• Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2.

  Biochimica et biophysica acta 20091201

• Guanosine-5'-monophosphate induces cell death in rat hippocampal slices via ionotropic glutamate receptors activation and glutamate uptake inhibition.

  Neurochemistry international 20091201

• Follicle development and luteal cell morphology altered by phosphodiesterase-5 inhibitor.

  Micron (Oxford, England : 1993) 20091201

• Modulation of guanosine 5'-diphosphate-D-mannose metabolism in recombinant Escherichia coli for production of guanosine 5'-diphosphate-L-fucose.

  Bioresource technology 20091201

• Modulating RNA structure and catalysis: lessons from small cleaving ribozymes.

  Cellular and molecular life sciences : CMLS 20091201

• Opioid use affects antioxidant activity and purine metabolism: preliminary results.

  Human psychopharmacology 20091201

• 20-125Iodo-14,15-epoxyeicosa-5(Z)-enoic acid: a high-affinity radioligand used to characterize the epoxyeicosatrienoic acid antagonist binding site.

  The Journal of pharmacology and experimental therapeutics 20091201

• Functional autoradiography and gene expression analysis applied to the characterization of the alpha2-adrenergic system in the chicken brain.

  Journal of chemical neuroanatomy 20091201

• The R1441C mutation alters the folding properties of the ROC domain of LRRK2.

  Biochimica et biophysica acta 20091201

• The rho guanosine 5'-triphosphatase, cell division cycle 42, is required for insulin-induced actin remodeling and glucagon-like peptide-1 secretion in the intestinal endocrine L cell.

  Endocrinology 20091201

• Nemo-like kinase is involved in NGF-induced neurite outgrowth via phosphorylating MAP1B and paxillin.

  Journal of neurochemistry 20091201

• Reinforcing feedback loop of renal cyclic guanosine 3' 5' -monophosphate and interstitial hydrostatic pressure in pressure-natriuresis.

  Hypertension (Dallas, Tex. : 1979) 20091201

• Free energy calculation of modified base-pair formation in explicit solvent: A predictive model.

  RNA (New York, N.Y.) 20091201

• Guanosine-induced synaptogenesis in the adult brain in vivo.

  Anatomical record (Hoboken, N.J. : 2007) 20091201

• The FAS -670A>G polymorphism influences susceptibility to systemic sclerosis phenotypes.

  Arthritis and rheumatism 20091201

• Protein kinase G controls brown fat cell differentiation and mitochondrial biogenesis.

  Science signaling 20091201

• Nonenzymatic oligomerization of activated nucleotides on hairpin templates.

  Current protocols in nucleic acid chemistry 20091201

• [Clinical efficacy of entecavir therapy and factors associated with treatment response in naive chronic hepatitis B patients].

  The Korean journal of hepatology 20091201

• Three dimensional structure of the MqsR:MqsA complex: a novel TA pair comprised of a toxin homologous to RelE and an antitoxin with unique properties.

  PLoS pathogens 20091201

• Recent insights into the mechanisms of vasospastic angina.

  Korean circulation journal 20091201

• N-terminal pro-B-type natriuretic Peptide in overweight and obese patients with and without diabetes: an analysis based on body mass index and left ventricular geometry.

  Korean circulation journal 20091201

• Relaxation patterns of human gastric corporal smooth muscle by cyclic nucleotides producing agents.

  The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20091201

• HBV and HCV therapy.

  Viruses 20091201

• Hydration structures of 2'-deoxyguanosine studied by IR-UV double resonance spectroscopy: comparison with guanosine.

  Physical chemistry chemical physics : PCCP 20091128

• RelB and RelE of Escherichia coli form a tight complex that represses transcription via the ribbon-helix-helix motif in RelB.

  Journal of molecular biology 20091127

• Nonpolymeric thermosensitive supramolecules.

  Journal of the American Chemical Society 20091125

• The GTPase activity of Escherichia coli FtsZ determines the magnitude of the FtsZ polymer bundling by ZapA in vitro.

  Biochemistry 20091124

• Guanosine + OH radical reaction in aqueous solution: a reinterpretation of the UV-vis data based on thermodynamic and kinetic calculations.

  Organic letters 20091119

• Direct chemiluminescence detection of nitric oxide in aqueous solutions using the natural nitric oxide target soluble guanylyl cyclase.

  Free radical biology & medicine 20091115

• A supramolecular Cu(II) metallocyclophane probe for guanosine 5'-monophosphate.

  Chemical communications (Cambridge, England) 20091114

• Probing the catalytic sites and activation mechanism of photoreceptor phosphodiesterase using radiolabeled phosphodiesterase inhibitors.

  The Journal of biological chemistry 20091113

• Toll-like receptor 7 selective synthetic oligoribonucleotide agonists: synthesis and structure-activity relationship studies.

  Journal of medicinal chemistry 20091112

• Structural evidence for a sequential release mechanism for activation of heterotrimeric G proteins.

  Journal of molecular biology 20091106

• Enhanced DNA binding capacity on up-regulated epidermal wild-type p53 in vitiligo by H2O2-mediated oxidation: a possible repair mechanism for DNA damage.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20091101

• Evaluation of the antipsychotic effect of bi-acetylated l-stepholidine (l-SPD-A), a novel dopamine and serotonin receptor dual ligand.

  Schizophrenia research 20091101

• Exercise activates redox-sensitive transcription factors and restores renal D1 receptor function in old rats.

  American journal of physiology. Renal physiology 20091101

• Trp fluorescence reveals an activation-dependent cation-pi interaction in the Switch II region of Galphai proteins.

  Protein science : a publication of the Protein Society 20091101

• Betulin-derived compounds as inhibitors of alphavirus replication.

  Journal of natural products 20091101

• Sources of extracellular, oxidatively-modified DNA lesions: implications for their measurement in urine.

  Journal of clinical biochemistry and nutrition 20091101

• Synthesis of guanosine and deoxyguanosine phosphoramidites with cross-linkable thioalkyl tethers for direct incorporation into RNA and DNA.

  Nucleosides, nucleotides & nucleic acids 20091101

• An atypical CNG channel activated by a single cGMP molecule controls sperm chemotaxis.

  Science signaling 20091027

• Transmembrane protein-free membranes fuse into xenopus nuclear envelope and promote assembly of functional pores.

  The Journal of biological chemistry 20091023

• Editing independent effects of ADARs on the miRNA/siRNA pathways.

  The EMBO journal 20091021

• Random amplified polymorphic DNA (RAPD) analysis and the nucleosides assessment of fungal strains isolated from natural Cordyceps sinensis.

  Journal of pharmaceutical and biomedical analysis 20091015

• Determination of nucleosides and nucleobases in different species of Cordyceps by capillary electrophoresis-mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20091015

• Efficient and rapid template-directed nucleic acid copying using 2'-amino-2',3'-dideoxyribonucleoside-5'-phosphorimidazolide monomers.

  Journal of the American Chemical Society 20091014

• Dopamine gene therapy for Parkinson's disease in a nonhuman primate without associated dyskinesia.

  Science translational medicine 20091014

• A potentially versatile nucleotide hydrolysis activity of group II chaperonin monomers from Thermoplasma acidophilum.

  Biochemistry 20091013

• Hard/soft selectivity in ligand substitution reactions of beta-diketonate platinum(II) complexes.

  Dalton transactions (Cambridge, England : 2003) 20091007

• The mammalian sympathetic prevertebral ganglia: models for the study of neuronal networks and basic neuronal properties.

  Autonomic neuroscience : basic & clinical 20091005

• Inhibition of tumour necrosis factor and IL-17 production by leflunomide involves the JAK/STAT pathway.

  Annals of the rheumatic diseases 20091001

• Potential therapeutic advantages of guanosine over inosine in multiple sclerosis.

  Medical hypotheses 20091001

• The dopaminergic stabilizer ASP2314/ACR16 selectively interacts with D2(High) receptors.

  Synapse (New York, N.Y.) 20091001

• Glutamate agonist LY404,039 for treating schizophrenia has affinity for the dopamine D2(High) receptor.

  Synapse (New York, N.Y.) 20091001

• Rac1 is required for cardiomyocyte apoptosis during hyperglycemia.

  Diabetes 20091001

• Mutant 5-hydroxytryptamine 1A receptor D116A is a receptor activated solely by synthetic ligands with a rich pharmacology.

  The Journal of pharmacology and experimental therapeutics 20091001

• The (p)ppGpp synthetase RelA contributes to stress adaptation and virulence in Enterococcus faecalis V583.

  Microbiology (Reading, England) 20091001

• Functional characterization of two isoforms of the P2Y-like receptor GPR17: [35S]GTPgammaS binding and electrophysiological studies in 1321N1 cells.

  American journal of physiology. Cell physiology 20091001

• Phosphodiesterase type 5 inhibitors facilitate noncontact erections in male rats: site of action in the brain and mechanism of action.

  The journal of sexual medicine 20091001

• CXCR2 inverse agonism detected by arrestin redistribution.

  Journal of biomolecular screening 20091001

• Molecular gate keepers succumb to gene aberrations in colorectal cancer in Kashmiri population, revealing a high incidence area.

  Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20091001

• Kissing G domains of MnmE monitored by X-ray crystallography and pulse electron paramagnetic resonance spectroscopy.

  PLoS biology 20091001

• EBNA1-mediated recruitment of a histone H2B deubiquitylating complex to the Epstein-Barr virus latent origin of DNA replication.

  PLoS pathogens 20091001

• Cloning and characterization of the rhesus monkey nociceptin/orphanin FQ receptor.

  Genes & genetic systems 20091001

• Synthesis of 3'-amino-3'-deoxyguanosine and 3'-amino-3'-deoxyxyloguanosine monophosphate HepDirect prodrugs from guanosine.

  Nucleosides, nucleotides & nucleic acids 20091001

• Purification and functional reconstitution of monomeric mu-opioid receptors: allosteric modulation of agonist binding by Gi2.

  The Journal of biological chemistry 20090925

• Leucyl-tRNA synthetase-dependent and -independent activation of a group I intron.

  The Journal of biological chemistry 20090925

• Pertussis toxin-sensitive signaling of melanocortin-4 receptors in hypothalamic GT1-7 cells defines agouti-related protein as a biased agonist.

  The Journal of biological chemistry 20090925

• Co-administration of the partial dopamine D2 agonist terguride with L-dopa attenuates L-dopa-induced locomotor sensitization in hemiparkinsonian mice.

  Behavioural brain research 20090914

• Manifestations of the mitochondrial A3243G mutation.

  International journal of cardiology 20090911

• Supramolecular structure and polymorphism of alkali metal salts of guanosine 5'-monophosphate: SEM and NMR study.

  The journal of physical chemistry. B 20090910

• Aqueous methods for the preparation of 5'-substituted guanosine derivatives.

  Chemical communications (Cambridge, England) 20090907

• Rigid rod and tetrahedral hybrid compounds featuring nucleobase and nucleoside end-capped structures.

  Organic & biomolecular chemistry 20090907

• Activation of protease calpain by oxidized and glycated LDL increases the degradation of endothelial nitric oxide synthase.

  Journal of cellular and molecular medicine 20090901

• Advances in preclinical therapeutics development using small animal imaging and molecular analyses: the gastrointestinal stromal tumors model.

  Clinical and experimental medicine 20090901

• The phosphorylation status of membrane-bound nucleoside diphosphate kinase in epithelia and the role of AMP.

  Molecular and cellular biochemistry 20090901

• Nucleoside diphosphate kinase (NDPK, NM23, AWD): recent regulatory advances in endocytosis, metastasis, psoriasis, insulin release, fetal erythroid lineage and heart failure; translational medicine exemplified.

  Molecular and cellular biochemistry 20090901

• DNA interactions and photocatalytic strand cleavage by artificial nucleases based on water-soluble gold(III) porphyrins.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20090901

• Exploring the mechanism of agonist efficacy: a relationship between efficacy and agonist dissociation rate at the muscarinic M3 receptor.

  Molecular pharmacology 20090901

• Synthesis, characterization, and reaction pathways for the formation of a GMP adduct of a cytotoxic thiocyanato ruthenium arene complex.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20090901

• Folate intake and bowel cancer risk.

  Genes & nutrition 20090901

• Automated method for the direct analysis of 8-oxo-guanosine and 8-oxo-2'-deoxyguanosine in human urine using ultraperformance liquid chromatography and tandem mass spectrometry.

  Free radical biology & medicine 20090901

• Effect of (r)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine (H2G) and AZT-lipid-PFA on human herpesvirus-6B infected cells.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20090901

• GDI-1 preferably interacts with Rab10 in insulin-stimulated GLUT4 translocation.

  The Biochemical journal 20090901

• Potential roles of melatonin and chronotherapy among the new trends in hypertension treatment.

  Journal of pineal research 20090901

• Molecular and cellular regulation of pancreatic acinar cell function.

  Current opinion in gastroenterology 20090901

• Temporal lobe epilepsy causes selective changes in mu opioid and nociceptin receptor binding and functional coupling to G-proteins in human temporal neocortex.

  Neurobiology of disease 20090901

• Measurement of one and two bond N-C couplings in large proteins by TROSY-based J-modulation experiments.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20090901

• Molecularly imprinted monolith in-tube solid-phase microextraction coupled with HPLC/UV detection for determination of 8-hydroxy-2'-deoxyguanosine in urine.

  Analytical and bioanalytical chemistry 20090901

• Development and validation of a gas chromatography/mass spectrometry method for the assessment of genomic DNA methylation.

  Rapid communications in mass spectrometry : RCM 20090901

• Novel delta opioid receptor agonists exhibit differential stimulation of signaling pathways.

  Bioorganic & medicinal chemistry 20090901

• Formation of spiroiminodihydantoin nucleoside from 8-oxo-7,8-dihydro-2'-deoxyguanosine by nitric oxide under aerobic conditions.

  Bioorganic & medicinal chemistry letters 20090901

• Can we improve outcome of congenital diaphragmatic hernia?

  Pediatric surgery international 20090901

• Weak toxin WTX from Naja kaouthia cobra venom interacts with both nicotinic and muscarinic acetylcholine receptors.

  The FEBS journal 20090901

• Towards a new understanding on the regulation of mammalian oocyte meiosis resumption.

  Cell cycle (Georgetown, Tex.) 20090901

• Mu opioid receptor from the zebrafish exhibits functional characteristics as those of mammalian mu opioid receptor.

  Zebrafish 20090901

• A cyclic GMP signalling module that regulates gliding motility in a malaria parasite.

  PLoS pathogens 20090901

• Marine-derived metabolites of S-adenosylmethionine as templates for new anti-infectives.

  Marine drugs 20090901

• [Chemical constituents of Momordica charantia L].

  Yao xue xue bao = Acta pharmaceutica Sinica 20090901

• Release of adenosine and ATP during ischemia and epilepsy.

  Current neuropharmacology 20090901

• Oxidation of the carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxy-naphthalene (Sudan I) by cytochromes P450 and peroxidases: a comparative study.

  Interdisciplinary toxicology 20090901

• Recruitment of the earliest component of the bacterial flagellum to the old cell division pole by a membrane-associated signal recognition particle family GTP-binding protein.

  Journal of molecular biology 20090828

• Evolution of ribozymes in an RNA world.

  Chemistry & biology 20090828

• A promiscuous ribozyme promotes nucleotide synthesis in addition to ribose chemistry.

  Chemistry & biology 20090828

• Anion exchange liquid chromatography for the determination of nucleotides in baby and/or functional foods.

  Journal of agricultural and food chemistry 20090826

• Inhibition of inosine monophosphate dehydrogenase reduces adipogenesis and diet-induced obesity.

  Biochemical and biophysical research communications 20090821

• Pd(0)/Cu(I)-mediated direct arylation of 2'-deoxyadenosines: mechanistic role of Cu(I) and reactivity comparisons with related purine nucleosides.

  The Journal of organic chemistry 20090821

• Activating mu-opioid receptors in the lateral parabrachial nucleus increases c-Fos expression in forebrain areas associated with caloric regulation, reward and cognition.

  Neuroscience 20090818

• Identification of cell culture conditions to control N-glycosylation site-occupancy of recombinant glycoproteins expressed in CHO cells.

  Biotechnology and bioengineering 20090815

• Synthesis and characterization of modified nucleotides in the 970 hairpin loop of Escherichia coli 16S ribosomal RNA.

  Bioorganic & medicinal chemistry 20090815

• Immobilization of self-quenched DNA hairpin probe with a heterobifunctional reagent on a glass surface for sensitive detection of oligonucleotides.

  Bioorganic & medicinal chemistry 20090815

• Synaptotagmin-like protein 1 interacts with the GTPase-activating protein Rap1GAP2 and regulates dense granule secretion in platelets.

  Blood 20090813

• Triazole inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase.

  Journal of medicinal chemistry 20090813

• Guanosine hydrogen-bonded scaffolds: a new way to control the bottom-up realisation of well-defined nanoarchitectures.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20090810

• Walking a supramolecular tightrope: a self-assembled dodecamer from an 8-aryl-2'-deoxyguanosine derivative.

  Journal of the American Chemical Society 20090805

• Structural and functional analysis of Sulfolobus solfataricus Y-family DNA polymerase Dpo4-catalyzed bypass of the malondialdehyde-deoxyguanosine adduct.

  Biochemistry 20090804

• Evidence for action of ribavirin through the hepatitis C virus RNA polymerase.

  Journal of viral hepatitis 20090801

• Complex plastic changes in the neuropeptide Y system during ethanol intoxication and withdrawal in the rat brain.

  Journal of neuroscience research 20090801

• Estradiol increases guanosine 5'-triphosphate cyclohydrolase expression via the nitric oxide-mediated activation of cyclic adenosine 5'-monophosphate response element binding protein.

  Endocrinology 20090801

• Magic spot: (p) ppGpp.

  Journal of cellular physiology 20090801

• Dopamine D2High receptors stimulated by phencyclidines, lysergic acid diethylamide, salvinorin A, and modafinil.

  Synapse (New York, N.Y.) 20090801

• Altered M(1) muscarinic acetylcholine receptor (CHRM1)-Galpha(q/11) coupling in a schizophrenia endophenotype.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090801

• Abstracts of the 2008 ISSOL Meeting. August 24-29, 2008. Florence, Italy.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20090801

• Sphingosine-1-phosphate receptors mediate neuromodulatory functions in the CNS.

  Journal of neurochemistry 20090801

• Fe(II) phthalocyanine catalyzed oxidation of dGMP by molecular oxygen.

  Bioorganic & medicinal chemistry letters 20090801

• The phosphoramidate ProTide approach greatly enhances the activity of beta-2'-C-methylguanosine against hepatitis C virus.

  Bioorganic & medicinal chemistry letters 20090801

• In vivo activation of AMP-activated protein kinase attenuates diabetes-enhanced degradation of GTP cyclohydrolase I.

  Diabetes 20090801

• A fast capillary electrophoresis method for separation and quantification of modified nucleosides in urinary samples.

  Analytical chemistry 20090801

• Structure of RNase Sa2 complexes with mononucleotides--new aspects of catalytic reaction and substrate recognition.

  The FEBS journal 20090801

• Toll-like receptor 7 and 9 defects in common variable immunodeficiency.

  The Journal of allergy and clinical immunology 20090801

• Cyclic adenosine monophosphate (cAMP)-specific phosphodiesterase is functional in bovine mammary gland.

  Journal of dairy science 20090801

• Preclinical assessment of the treatment of second-stage African trypanosomiasis with cordycepin and deoxycoformycin.

  PLoS neglected tropical diseases 20090801

• Genome-wide scan of 500,000 single-nucleotide polymorphisms among responders and nonresponders to interferon beta therapy in multiple sclerosis.

  Archives of neurology 20090801

• Relationship of urinary cGMP excretion with aging and menopausal status in a general population.

  Journal of atherosclerosis and thrombosis 20090801

• Persistent cAMP-signals triggered by internalized G-protein-coupled receptors.

  PLoS biology 20090801

• Autocatalytic loop, amplification and diffusion: a mathematical and computational model of cell polarization in neural chemotaxis.

  PLoS computational biology 20090801

• [Umbilical cord plasma endothelin 1 and cyclic guanosine concentrations monophosphate at delivery in pregnancy complicated by diabetes mellitus].

  Ginekologia polska 20090801

• A new odorless procedure for the synthesis of 2'-deoxy-6-thioguanosine and its incorporation into oligodeoxynucleotides.

  Nucleosides, nucleotides & nucleic acids 20090801

• Role of the general base Glu-268 in nitroglycerin bioactivation and superoxide formation by aldehyde dehydrogenase-2.

  The Journal of biological chemistry 20090724

• Structural interpretation of J coupling constants in guanosine and deoxyguanosine: modeling the effects of sugar pucker, backbone conformation, and base pairing.

  The journal of physical chemistry. A 20090723

• Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation.

  Cell 20090723

• A simple method for C-6 modification of guanine nucleosides.

  Organic & biomolecular chemistry 20090721

• ENDOR spectroscopy shows that guanine N1 binds to [4Fe-4S] cluster II of the S-adenosylmethionine-dependent enzyme MoaA: mechanistic implications.

  Journal of the American Chemical Society 20090708

• DNA repair and DNA triplet repeat expansion: the impact of abasic lesions on triplet repeat DNA energetics.

  Journal of the American Chemical Society 20090708

• Insulin action on polyunsaturated phosphatidic acid formation in rat brain: an 'in vitro' model with synaptic endings from cerebral cortex and hippocampus.

  Neurochemical research 20090701

• Palmitoylation modification of Galpha(o) depresses its susceptibility to GAP-43 activation.

  The international journal of biochemistry & cell biology 20090701

• Effects of the NO donor sodium nitroprusside on oxygen consumption and energetics in rabbit myocardium.

  Basic research in cardiology 20090701

• Another ten stories in antiviral drug discovery (part C): 'Old' and 'new' antivirals, strategies, and perspectives.

  Medicinal research reviews 20090701

• RNA oxidation in Alzheimer disease and related neurodegenerative disorders.

  Acta neuropathologica 20090701

• Increase of uric acid and purine compounds in biological fluids of multiple sclerosis patients.

  Clinical biochemistry 20090701

• Delta receptors are required for full inhibitory coupling of mu-receptors to voltage-dependent Ca(2+) channels in dorsal root ganglion neurons.

  Molecular pharmacology 20090701

• Biochemical characterisation of the D60A mutant of the elongation factor 1alpha from the archaeon Sulfolobus solfataricus.

  Biochimie 20090701

• Activation switch in the transmembrane domain of metabotropic glutamate receptor.

  Molecular pharmacology 20090701

• The signal pathway of gonadotrophins-induced mammalian oocyte meiotic resumption.

  Molecular human reproduction 20090701

• Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist Compound 24.

  European journal of pharmacology 20090701

• Influence of nucleotide identity on ribose 2'-hydroxyl reactivity in RNA.

  RNA (New York, N.Y.) 20090701

• Efficient solid-phase synthesis of oligodeoxynucleotides having a 5'-terminal 2,2,7-trimethylguanosine pyrophosphate linkage.

  Bioorganic & medicinal chemistry 20090701

• Origin of an alternative genetic code in the extremely small and GC-rich genome of a bacterial symbiont.

  PLoS genetics 20090701

• Effect of food on the pharmacokinetics of the oral phosphodiesterase 5 inhibitor udenafil for the treatment of erectile dysfunction.

  British journal of clinical pharmacology 20090701

• Phosphodiesterase 3 (PDE3): structure, localization and function.

  Cardiovascular & hematological agents in medicinal chemistry 20090701

• Applications of isothermal titration calorimetry in biophysical studies of G-quadruplexes.

  International journal of molecular sciences 20090701

• Mycophenolate mofetil: An update.

  Drugs of today (Barcelona, Spain : 1998) 20090701

• New approaches for cancer treatment: antitumor drugs based on gene-targeted nucleic acids.

  Acta naturae 20090701

• Identification and characterization of a novel lysophosphatidic acid receptor, p2y5/LPA6.

  The Journal of biological chemistry 20090626

• The action and mode of binding of thiazolidinedione ligands at free fatty acid receptor 1.

  The Journal of biological chemistry 20090626

• Metaplasticity of hypothalamic synapses following in vivo challenge.

  Neuron 20090625

• Spinal mechanisms of antinociceptive action caused by guanosine in mice.

  European journal of pharmacology 20090624

• Productive versus unproductive nucleotide binding in yeast guanylate kinase mutants: comparison of R41M with K14M by proton two dimensional transferred NOESY.

  Biochemistry 20090623

• A CA(+) pair adjacent to a sheared GA or AA pair stabilizes size-symmetric RNA internal loops.

  Biochemistry 20090623

• Conserved glutamate residues Glu-343 and Glu-519 provide mechanistic insights into cation/nucleoside cotransport by human concentrative nucleoside transporter hCNT3.

  The Journal of biological chemistry 20090619

• Cytokine modulation of TLR expression and activation in mesenchymal stromal cells leads to a proinflammatory phenotype.

  Journal of immunology (Baltimore, Md. : 1950) 20090615

• The P2Y12 antagonists, 2-methylthioadenosine 5'-monophosphate triethylammonium salt and cangrelor (ARC69931MX), can inhibit human platelet aggregation through a Gi-independent increase in cAMP levels.

  The Journal of biological chemistry 20090612

• The action of 11-cis-retinol on cone opsins and intact cone photoreceptors.

  The Journal of biological chemistry 20090612

• Degradation of ppGpp by nudix pyrophosphatase modulates the transition of growth phase in the bacterium Thermus thermophilus.

  The Journal of biological chemistry 20090605

• Kinetic analysis of the guanine nucleotide exchange activity of TRAPP, a multimeric Ypt1p exchange factor.

  Journal of molecular biology 20090605

• Small angle X-ray scattering analysis of deoxyguanosine 5'-monophosphate self-assembing in solution: nucleation and growth of G-quadruplexes.

  The journal of physical chemistry. B 20090604

• Novel crosstalk to BMP signalling: cGMP-dependent kinase I modulates BMP receptor and Smad activity.

  The EMBO journal 20090603

• Transition state structures and the roles of catalytic residues in GAP-facilitated GTPase of Ras as elucidated by (18)O kinetic isotope effects.

  Biochemistry 20090602

• Importance of schedule of administration in the therapeutic efficacy of guanosine: early intervention after injury enhances glutamate uptake in model of hypoxia-ischemia.

  Journal of molecular neuroscience : MN 20090601

• Fetal Hemoglobin Inducers from the Natural World: A Novel Approach for Identification of Drugs for the Treatment of {beta}-Thalassemia and Sickle-Cell Anemia.

  Evidence-based complementary and alternative medicine : eCAM 20090601

• Kinetic determination of the GTPase activity of Ras proteins by means of a luminescent terbium complex.

  Analytical and bioanalytical chemistry 20090601

• The Hellenic type of nondeletional hereditary persistence of fetal hemoglobin results from a novel mutation (g.-109G>T) in the HBG2 gene promoter.

  Annals of hematology 20090601

• Autoantibodies in type 2 diabetes induce stress fiber formation and apoptosis in endothelial cells.

  The Journal of clinical endocrinology and metabolism 20090601

• Mycophenolic acid inhibits PMA-induced activation of the neutrophil respiratory burst.

  Transplant infectious disease : an official journal of the Transplantation Society 20090601

• Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics.

  Pharmacology & therapeutics 20090601

• Characterization of mouse heart adenylyl cyclase.

  The Journal of pharmacology and experimental therapeutics 20090601

• Adenosine deamination to inosine in isolated basolateral membrane from kidney proximal tubule: implications for modulation of the membrane-associated protein kinase A.

  Archives of biochemistry and biophysics 20090601

• Bradykinin inhibits the transient outward K+ current in mouse Schwann cells via the cAMP/PKA pathway.

  American journal of physiology. Cell physiology 20090601

• The cyclic GMP modulators YC-1 and zaprinast reduce vessel remodeling through antiproliferative and proapoptotic effects.

  Journal of cardiovascular pharmacology and therapeutics 20090601

• G protein independent phosphorylation and internalization of the delta-opioid receptor.

  Journal of neurochemistry 20090601

• Gating charges per channel of Ca(V)2.2 channels are modified by G protein activation in rat sympathetic neurons.

  Archives of biochemistry and biophysics 20090601

• Pharmacodynamics of a novel designer natriuretic peptide, CD-NP, in a first-in-human clinical trial in healthy subjects.

  Journal of clinical pharmacology 20090601

• Borrelia burgdorferi bb0426 encodes a 2'-deoxyribosyltransferase that plays a central role in purine salvage.

  Molecular microbiology 20090601

• Cloning and characterization of a gene encoding Rac/Rop-like monomeric guanosine 5'-triphosphate-binding protein from Scoparia dulcis.

  Biological & pharmaceutical bulletin 20090601

• Absolute configurations of spiroiminodihydantoin and allantoin stereoisomers: comparison of computed and measured electronic circular dichroism spectra.

  Chemical research in toxicology 20090601

• Inhibition of Lassa virus glycoprotein cleavage and multicycle replication by site 1 protease-adapted alpha(1)-antitrypsin variants.

  PLoS neglected tropical diseases 20090601

• The glyceraldehyde-3-phosphate dehydrogenase and the small GTPase Rab 2 are crucial for Brucella replication.

  PLoS pathogens 20090601

• Carbachol regulates pacemaker activities in cultured interstitial cells of Cajal from the mouse small intestine.

  Molecules and cells 20090531

• Crystal structure of the nuclear export receptor CRM1 in complex with Snurportin1 and RanGTP.

  Science (New York, N.Y.) 20090522

• Apparent non-statistical binding in a ditopic receptor for guanosine.

  Organic & biomolecular chemistry 20090521

• Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.

  Chemical research in toxicology 20090518

• Electrochemical behaviors of guanosine on carbon ionic liquid electrode and its determination.

  Talanta 20090515

• Rapid changes in shear stress induce dissociation of a G alpha(q/11)-platelet endothelial cell adhesion molecule-1 complex.

  The Journal of physiology 20090515

• The deazapurine biosynthetic pathway revealed: in vitro enzymatic synthesis of PreQ(0) from guanosine 5'-triphosphate in four steps.

  Biochemistry 20090512

• Epitope-tagged receptor knock-in mice reveal that differential desensitization of alpha2-adrenergic responses is because of ligand-selective internalization.

  The Journal of biological chemistry 20090508

• Influence of water hydrogen bonding on the reactions of arylnitrenium ions with guanosine: hydrogen-bonding effects can favor reaction at the C8 site.

  The journal of physical chemistry. B 20090507

• Bacterial alarmone, guanosine 5'-diphosphate 3'-diphosphate (ppGpp), predominantly binds the beta' subunit of plastid-encoded plastid RNA polymerase in chloroplasts.

  Chembiochem : a European journal of chemical biology 20090504

• The N-terminal domain of GPR61, an orphan G-protein-coupled receptor, is essential for its constitutive activity.

  Journal of neuroscience research 20090501

• The in vitro and in ovo responses of chickens to TLR9 subfamily ligands.

  Developmental and comparative immunology 20090501

• Calpain-mediated degradation of G-substrate plays a critical role in retinal excitotoxicity for amacrine cells.

  Journal of neuroscience research 20090501

• Effect of sildenafil on acrolein-induced airway inflammation and mucus production in rats.

  The European respiratory journal 20090501

• Phenolic acids suppress adipocyte lipolysis via activation of the nicotinic acid receptor GPR109A (HM74a/PUMA-G).

  Journal of lipid research 20090501

• Separation and identification of purine nucleosides in the urine of patients with malignant cancer by reverse phase liquid chromatography/electrospray tandem mass spectrometry.

  Journal of mass spectrometry : JMS 20090501

• Interstitial cells of Cajal contain signalling molecules for transduction of nitrergic stimulation in guinea pig caecum.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20090501

• Plant and fungal Fpg homologs are formamidopyrimidine DNA glycosylases but not 8-oxoguanine DNA glycosylases.

  DNA repair 20090501

• A class C CpG toll-like receptor 9 agonist successfully induces robust interferon-alpha production by plasmacytoid dendritic cells from patients chronically infected with hepatitis C.

  Journal of viral hepatitis 20090501

• A functional link between T-type calcium channels and mu-opioid receptor expression in adult primary sensory neurons.

  Journal of neurochemistry 20090501

• Functional role of J domain of cysteine string protein in Ca2+-dependent secretion from acinar cells.

  American journal of physiology. Gastrointestinal and liver physiology 20090501

• Activators of G proteins inhibit GSK-3beta and stabilize beta-Catenin in Xenopus oocytes.

  Biochemical and biophysical research communications 20090501

• Neurofibromatosis type 1 and associated malignancies.

  Current neurology and neuroscience reports 20090501

• Ser/Thr/Tyr phosphoproteome analysis of pathogenic and non-pathogenic Pseudomonas species.

  Proteomics 20090501

• The SARS-unique domain (SUD) of SARS coronavirus contains two macrodomains that bind G-quadruplexes.

  PLoS pathogens 20090501

• Modulation of RNA metal binding by flanking bases: 15N NMR evaluation of GC, tandem GU, and tandem GA sites.

  Nucleosides, nucleotides & nucleic acids 20090501

• G-quadruplex self-assembly regulated by Coulombic interactions.

  Nature chemistry 20090501

• The presence of circulating total DNA and methylated genes is associated with circulating tumour cells in blood from breast cancer patients.

  British journal of cancer 20090421

• IR-UV double resonance spectroscopy of the hydrated clusters of guanosine and 9-methylguanine: evidence for hydration structures involving the sugar group.

  The journal of physical chemistry. A 20090416

• A novel method for the detection of point mutation in DNA using single-base-coded CdS nanoprobes.

  Biosensors & bioelectronics 20090415

• [35S]GTP gamma S binding studies of amphiphilic drugs-activated Gi proteins: a caveat.

  Bioorganic & medicinal chemistry letters 20090415

• The significance of EXDD and RXKD motif conservation in Rel proteins.

  The Journal of biological chemistry 20090403

• Stabilizing guanosine-sterol ion channels with a carbamate to urea modification in the linker.

  Organic letters 20090402

• Mycophenolic acid inhibits oleic acid-induced mesangial cell activation through both cellular reactive oxygen species and inosine monophosphate dehydrogenase 2 pathways.

  Pediatric nephrology (Berlin, Germany) 20090401

• Extracellular guanosine and GTP promote expression of differentiation markers and induce S-phase cell-cycle arrest in human SH-SY5Y neuroblastoma cells.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20090401

• Cholinergic direct inhibition of N-methyl-D aspartate receptor-mediated currents in the rat neocortex.

  Synapse (New York, N.Y.) 20090401

• JNJ-20788560 [9-(8-azabicyclo[3.2.1]oct-3-ylidene)-9H-xanthene-3-carboxylic acid diethylamide], a selective delta opioid receptor agonist, is a potent and efficacious antihyperalgesic agent that does not produce respiratory depression, pharmacologic tolerance, or physical dependence.

  The Journal of pharmacology and experimental therapeutics 20090401

• Toll-like receptor 7 cooperates with IL-4 in activated B cells through antigen receptor or CD38 and induces class switch recombination and IgG1 production.

  Molecular immunology 20090401

• Facilitated mitochondrial import of antiviral and anticancer nucleoside drugs by human equilibrative nucleoside transporter-3.

  American journal of physiology. Gastrointestinal and liver physiology 20090401

• Evaluation of urinary nucleosides in breast cancer patients before and after tumor removal.

  Clinical biochemistry 20090401

• Suppression of prostaglandin E2-induced MUC5AC overproduction by RGS4 in the airway.

  American journal of physiology. Lung cellular and molecular physiology 20090401

• Exogenous adenosine reduces the mitochondrial membrane potential of murine oocytes during the latter half of in vitro maturation and pronuclear formation following chemical activation.

  The Journal of reproduction and development 20090401

• Cerebral haemodynamic response or excitability is not affected by sildenafil.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090401

• Characterization of a mimivirus RNA cap guanine-N2 methyltransferase.

  RNA (New York, N.Y.) 20090401

• Differential effects of calcium-channel blockers on vascular endothelial function in patients with coronary spastic angina.

  Circulation journal : official journal of the Japanese Circulation Society 20090401

• Agonist activity of N-desmethylclozapine at delta-opioid receptors of human frontal cortex.

  European journal of pharmacology 20090401

• The purine nucleosides adenosine and guanosine delay axonal degeneration in vitro.

  Journal of neurochemistry 20090401

• The Borrelia burgdorferi flaB promoter has an extended -10 element and includes a T-rich -35/-10 spacer sequence that is essential for optimal activity.

  FEMS microbiology letters 20090401

• Stringent response in Vibrio cholerae: genetic analysis of spoT gene function and identification of a novel (p)ppGpp synthetase gene.

  Molecular microbiology 20090401

• Structure analysis of the conserved methyltransferase domain of human trimethylguanosine synthase TGS1.

  Acta crystallographica. Section D, Biological crystallography 20090401

• Isolation of plasma membrane compartments from rat brain cortex; detection of agonist-stimulated G protein activity.

  Medical science monitor : international medical journal of experimental and clinical research 20090401

• A study of the pH dependence of electronically excited guanosine compounds by picosecond time-resolved infrared spectroscopy.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20090401

• Endocannabinoid-mediated long-term depression in the avian midbrain expressed presynaptically and postsynaptically.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090401

• Receptor-independent modulation of reconstituted Galpha(i) protein mediated by liposomes.

  Molecular bioSystems 20090401

• Vessel dilator and kaliuretic peptide inhibit Ras in human prostate cancer cells.

  Anticancer research 20090401

• [Molecular regulation of microbial secondary metabolites--a review].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20090401

• Site-specific regulation of CA(V)2.2 channels by protein kinase C isozymes betaII and epsilon.

  Neuroscience 20090317

• Quantitative analysis of RNA solvent accessibility by N-silylation of guanosine.

  Biochemistry 20090317

• Mechanistic aspects of the formation of guanidinohydantoin from spiroiminodihydantoin under acidic conditions.

  Chemical research in toxicology 20090316

• Characterization of oxidized guanosine 5'-triphosphate as a viable inhibitor of soluble guanylyl cyclase.

  Free radical biology & medicine 20090315

• Qualitative evaluation and quantitative determination of 10 major active components in Carthamus tinctorius L. by high-performance liquid chromatography coupled with diode array detector.

  Journal of chromatography. A 20090313

• APOBEC proteins and intrinsic resistance to HIV-1 infection.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312

• Helical structure of disodium 5'-guanosine monophosphate self-assembly in neutral solution.

  Journal of the American Chemical Society 20090311

• Solvent-induced high fidelity switching between two discrete supramolecules.

  Journal of the American Chemical Society 20090311

• Synthesis of 2'-C-beta-methyl-2'-deoxyguanosine.

  The Journal of organic chemistry 20090306

• Specific regulation of mRNA cap methylation by the c-Myc and E2F1 transcription factors.

  Oncogene 20090305

• Responses to 5-HT in morphologically identified neurons in the rat substantia gelatinosa in vitro.

  Neuroscience 20090303

• Development of selective agonists and antagonists of P2Y receptors.

  Purinergic signalling 20090301

• Allosteric modulation of adenosine receptors.

  Purinergic signalling 20090301

• S100B overexpressing mutant mice exhibit prolonged behavioural and biochemical responses towards repeated intermittent binge treatments with MDMA.

  The international journal of neuropsychopharmacology 20090301

• Ceramide 1-phosphate (C1P) promotes cell migration Involvement of a specific C1P receptor.

  Cellular signalling 20090301

• Glutamate receptor mGlu2 and mGlu3 knockout striata are dopamine supersensitive, with elevated D2(High) receptors and marked supersensitivity to the dopamine agonist (+)PHNO.

  Synapse (New York, N.Y.) 20090301

• Pharmacological assessments of nitric oxide synthase isoforms and downstream diversity of NO signaling in the maintenance of thermal and mechanical hypersensitivity after peripheral nerve injury in mice.

  Neuropharmacology 20090301

• Biochemical characterization and homology modeling of a purine-specific ribonucleoside hydrolase from the archaeon Sulfolobus solfataricus: insights into mechanisms of protein stabilization.

  Archives of biochemistry and biophysics 20090301

• GTPgammaS antagonizes the mastoparan-induced in vitro activity of PIP-phospholipase C from symbiotic root nodules of Phaseolus vulgaris.

  Physiologia plantarum 20090301

• Allosteric modulation of metabotropic glutamate receptor 5 affects phosphorylation, internalization, and desensitization of the micro-opioid receptor.

  Neuropharmacology 20090301

• Guanosine and synthetic organoselenium compounds modulate methylmercury-induced oxidative stress in rat brain cortical slices: involvement of oxidative stress and glutamatergic system.

  Toxicology in vitro : an international journal published in association with BIBRA 20090301

• Side-on binding of p-sulphonatocalix[4]arene to the dinuclear platinum complex trans-[{PtCl(NH3)2}2mu-dpzm]2+ and its implications for anticancer drug delivery.

  Journal of inorganic biochemistry 20090301

• Modulation of the cGMP signaling pathway by melatonin in pancreatic beta-cells.

  Journal of pineal research 20090301

• U18666A, a cholesterol-inhibition agent, modulates human neuronal nicotinic acetylcholine receptors heterologously expressed in SH-EP1 cell line.

  Journal of neurochemistry 20090301

• Altered CB receptor-signaling in prefrontal cortex from an animal model of depression is reversed by chronic fluoxetine.

  Journal of neurochemistry 20090301

• Role of natriuretic peptides in cGMP production in fetal cardiac bypass.

  The Annals of thoracic surgery 20090301

• Expression of ABCC-type nucleotide exporters in blasts of adult acute myeloid leukemia: relation to long-term survival.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090301

• Escherichia coli MazF leads to the simultaneous selective synthesis of both 'death proteins' and 'survival proteins'.

  PLoS genetics 20090301

• Bacterial toxin-antitoxin systems: more than selfish entities?

  PLoS genetics 20090301

• Mycophenolic Acid Inhibits p38 Mitogen-Activated Protein Kinase in Human Monocyte-Derived Dendritic Cells Stimulated by Lipopolysaccharide.

  Transplantation proceedings 20090301

• Hepatitis B in HIV patients: what is the current treatment and what are the challenges?

  Journal of HIV therapy 20090301

• Functional characteristics of TRPC4 channels expressed in HEK 293 cells.

  Molecules and cells 20090227

• Morphine increases brain levels of ferritin heavy chain leading to inhibition of CXCR4-mediated survival signaling in neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090225

• Reaction of hydrated electrons with guanine derivatives: tautomerism of intermediate species.

  The journal of physical chemistry. B 20090219

• High constitutive activity and a G-protein-independent high-affinity state of the human histamine H(4)-receptor.

  Biochemistry 20090217

• Guanosine improves motor behavior, reduces apoptosis, and stimulates neurogenesis in rats with parkinsonism.

  Journal of neuroscience research 20090215

• Development and validation of an LC-MS/MS method for quantification of cyclic guanosine 3',5'-monophosphate (cGMP) in clinical applications: a comparison with a EIA method.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090215

• Guanidine and 2-aminoimidazoline aromatic derivatives as alpha2-adrenoceptor ligands: searching for structure-activity relationships.

  Journal of medicinal chemistry 20090212

• Analysis of flavivirus NS5 methyltransferase cap binding.

  Journal of molecular biology 20090206

• Oxidation and glycolytic cleavage of etheno and propano DNA base adducts.

  Biochemistry 20090203

• Determinants of the voltage dependence of G protein modulation within calcium channel beta subunits.

  Pflugers Archiv : European journal of physiology 20090201

• Interaction of retinal guanylate cyclase with the alpha subunit of transducin: potential role in transducin localization.

  The Biochemical journal 20090201

• The NMDA antagonist MK-801 induces hyperalgesia and increases CSF excitatory amino acids in rats: reversal by guanosine.

  Pharmacology, biochemistry, and behavior 20090201

• Biochemical characterization of rab proteins from Bombyx mori.

  Archives of insect biochemistry and physiology 20090201

• Allosteric modulation of 5-HT(1A) receptors by zinc: Binding studies.

  Neuropharmacology 20090201

• Chronic high-NaCl intake prolongs the cardiorenal responses to central N/OFQ and produces regional changes in the endogenous brain NOP receptor system.

  American journal of physiology. Regulatory, integrative and comparative physiology 20090201

• Sphingosine-1-phosphate induced mTOR-activation is mediated by the E3-ubiquitin ligase PAM.

  Cellular signalling 20090201

• Acute and chronic effects of citalopram on 5-HT1A receptor-labeling by [18F]MPPF and -coupling to receptors-G proteins.

  Synapse (New York, N.Y.) 20090201

• SpoT governs Legionella pneumophila differentiation in host macrophages.

  Molecular microbiology 20090201

• The RhoGDI-alpha/JNK signaling pathway plays a significant role in mycophenolic acid-induced apoptosis in an insulin-secreting cell line.

  Cellular signalling 20090201

• Regulation of IL2 and NUCB1 in mononuclear cells treated with acyl glucuronide of mycophenolic acid reveals effects independent of inosine monophosphate dehydrogenase inhibition.

  Therapeutic drug monitoring 20090201

• A natural ribozyme with 3',5' RNA ligase activity.

  Nature chemical biology 20090201

• The ontogenetic expression pattern of type 5 phosphodiesterase correlates with androgen receptor expression in rat corpora cavernosa.

  The journal of sexual medicine 20090201

• High-throughput screening for small-molecule inhibitors of LARG-stimulated RhoA nucleotide binding via a novel fluorescence polarization assay.

  Journal of biomolecular screening 20090201

• Protection of mice against X-ray injuries by the post-irradiation administration of guanosine and inosine.

  International journal of radiation biology 20090201

• The psychostimulant d-threo-(R,R)-methylphenidate binds as an agonist to the 5HT(1A) receptor.

  Die Pharmazie 20090201

• Binding studies of novel, non-mammalian enkephalins, structures predicted from frog and lungfish brain cDNA sequences.

  Neuroscience 20090123

• Increased oxidative stress in patients with amyotrophic lateral sclerosis/Parkinsonism-dementia complex in the Kii peninsula, Japan.

  Movement disorders : official journal of the Movement Disorder Society 20090115

• Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 7: syntheses and opioid receptor properties of cyclic variants of cyclazocine.

  Bioorganic & medicinal chemistry letters 20090115

• Electronic structure of DNA--unique properties of 8-oxoguanosine.

  Journal of the American Chemical Society 20090114

• Glucocorticoids regulate glutamate and GABA synapse-specific retrograde transmission via divergent nongenomic signaling pathways.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090114

• Regulation of long-term depression by increases in [guanosine 3',5'-cyclic monophosphate] in the hippocampal CA1 region of freely behaving rats.

  Neuroscience 20090112

• Stimulation of mammalian G-protein-responsive adenylyl cyclases by carbon dioxide.

  The Journal of biological chemistry 20090109

• The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation.

  The Journal of biological chemistry 20090109

• Cloning and pharmacological characterization of a novel gene encoding human nucleoside transporter 1 (hNT1) from a human breast cancer cDNA library.

  Life sciences 20090102

• Investigating oxidative DNA damage and its repair using the comet assay.

  Mutation research 20090101

• Activation of G proteins and extracellular signal-regulated kinase 1/2 phosphorylation via human dopamine D4.4 receptors: differential pathway-dependent potencies of receptor agonists.

  Naunyn-Schmiedeberg's archives of pharmacology 20090101

• Selective phosphodiesterase inhibitors: a promising target for cognition enhancement.

  Psychopharmacology 20090101

• Mycophenolic acid inhibits the autocrine PDGF-B synthesis and PDGF-BB-induced mRNA expression of Egr-1 in rat mesangial cells.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090101

• Progestin signaling through an olfactory G protein and membrane progestin receptor-alpha in Atlantic croaker sperm: potential role in induction of sperm hypermotility.

  Endocrinology 20090101

• Mitochondrial DNA damage is a hallmark of chemically induced and the R6/2 transgenic model of Huntington's disease.

  DNA repair 20090101

• The Gq and G12 families of heterotrimeric G proteins report functional selectivity.

  Molecular pharmacology 20090101

• Role of Src in ligand-specific regulation of delta-opioid receptor desensitization and internalization.

  Journal of neurochemistry 20090101

• cGMP in the vasculature.

  Handbook of experimental pharmacology 20090101

• cGMP signalling in the mammalian brain: role in synaptic plasticity and behaviour.

  Handbook of experimental pharmacology 20090101

• Acetylation of the amino group on guanosine induced by nitric oxide in acetonitrile under aerobic conditions.

  Chemical & pharmaceutical bulletin 20090101

• Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases.

  BMC medical genomics 20090101

• Anti-nociceptive properties of the xanthine oxidase inhibitor allopurinol in mice: role of A1 adenosine receptors.

  British journal of pharmacology 20090101

• Humanized ADEPT comprised of an engineered human purine nucleoside phosphorylase and a tumor targeting peptide for treatment of cancer.

  Molecular cancer therapeutics 20090101

• TraR, a homolog of a RNAP secondary channel interactor, modulates transcription.

  PLoS genetics 20090101

• Novel exon of mammalian ADAR2 extends open reading frame.

  PloS one 20090101

• Transcriptomic comparison of Aspergillus niger growing on two different sugars reveals coordinated regulation of the secretory pathway.

  BMC genomics 20090101

• Evidence for niche adaptation in the genome of the bovine pathogen Streptococcus uberis.

  BMC genomics 20090101

• Therapeutic antioxidant medical gas.

  Journal of clinical biochemistry and nutrition 20090101

• 8-Oxo-7,8-dihydro-2'-deoxyguanosine Forms a Relatively Unstable Tetrameric Structure Compared with 2'-Deoxyguanosine.

  Journal of clinical biochemistry and nutrition 20090101

• Escherichia coli genes affecting recipient ability in plasmid conjugation: are there any?

  BMC genomics 20090101

• Comparison between the HCV IRES domain IV RNA structure and the Iron Responsive Element.

  Journal of negative results in biomedicine 20090101

• A reevaluation of the ambident reactivity of the guanine moiety towards hydroxyl radicals.

  Angewandte Chemie (International ed. in English) 20090101

• Outline of a genome navigation system based on the properties of GA-sequences and their flanks.

  PloS one 20090101

• Reconstruction of metabolic pathways for the cattle genome.

  BMC systems biology 20090101

• Receptor-induced dilatation in the systemic and intrarenal adaptation to pregnancy in rats.

  PloS one 20090101

• cGMP-dependent protein kinase I is crucial for angiogenesis and postnatal vasculogenesis.

  PloS one 20090101

• Segment-dependent activation of muscarinic acetylcholine receptor-mediated [35S]Guanosine-5'-O-(gamma-thiotriphosphate) binding in airway tissue membranes.

  Pharmacology 20090101

• [Effect of estradiol on Ca2+ release from intracellular stores in porcine oocytes stimulated by prolactin, theophylline, or guanosine triphosphate].

  Ontogenez 20090101

• Prediction of breast cancer by profiling of urinary RNA metabolites using Support Vector Machine-based feature selection.

  BMC cancer 20090101

• Constraint-based analysis of metabolic capacity of Salmonella typhimurium during host-pathogen interaction.

  BMC systems biology 20090101

• Inhibition of Rac and Rac-linked functions by 8-oxo-2'-deoxyguanosine in murine macrophages.

  Free radical research 20090101

• Bioinformatics analysis suggests base modifications of tRNAs and miRNAs in Arabidopsis thaliana.

  BMC genomics 20090101

• Analysis of the Rickettsia africae genome reveals that virulence acquisition in Rickettsia species may be explained by genome reduction.

  BMC genomics 20090101

• Proteome serological determination of tumor-associated antigens in melanoma.

  PloS one 20090101

• The effect of high glucocorticoid administration and food restriction on rodent skeletal muscle mitochondrial function and protein metabolism.

  PloS one 20090101

• Hydroxyl radical oxidation of guanosine 5'-triphosphate (GTP): requirement for a GTP-Cu(II) complex.

  Redox report : communications in free radical research 20090101

• Short hairpin-loop-structured oligodeoxynucleotides reduce HSV-1 replication.

  Virology journal 20090101

• Molecular profiles of Quadriceps muscle in myostatin-null mice reveal PI3K and apoptotic pathways as myostatin targets.

  BMC genomics 20090101

• Comparative component analysis of exons with different splicing frequencies.

  PloS one 20090101

• Overexpression of nuclear transport factor 2 may protect against diabetic retinopathy.

  Molecular vision 20090101

• Mycophenolate mofetil: safety and efficacy in the prophylaxis of acute kidney transplantation rejection.

  Therapeutics and clinical risk management 20090101

• Comprehensive comparative-genomic analysis of type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes.

  Biology direct 20090101

• [35S]GTPgammaS binding in G protein-coupled receptor assays.

  Methods in molecular biology (Clifton, N.J.) 20090101

• The encapsulation and release of guanosine from PEGylated liposomes.

  Journal of liposome research 20090101

• Cigarette smoke attenuates the production of cytokines by human plasmacytoid dendritic cells and enhances the release of IL-8 in response to TLR-9 stimulation.

  Respiratory research 20090101

• Bench-to-bedside review: Inhaled nitric oxide therapy in adults.

  Critical care (London, England) 20090101

• The immune system and the impact of zinc during aging.

  Immunity & ageing : I & A 20090101

• Hypoglycemic herbs and their action mechanisms.

  Chinese medicine 20090101

• [The preparative method for 2-fluoroadenosine synthesis].

  Bioorganicheskaia khimiia 20090101

• Simultaneous live cell imaging using dual FRET sensors with a single excitation light.

  PloS one 20090101

• G-rich oligonucleotides for cancer treatment.

  Methods in molecular biology (Clifton, N.J.) 20090101

• Intracellular localization and conformational state of transglutaminase 2: implications for cell death.

  PloS one 20090101

• Conservation of structure and activity in Plasmodium purine nucleoside phosphorylases.

  BMC structural biology 20090101

• Purine nucleoside phosphorylase deficiency in two unrelated Saudi patients.

  Annals of Saudi medicine 20090101

• Rab4b is a small GTPase involved in the control of the glucose transporter GLUT4 localization in adipocyte.

  PloS one 20090101

• Illuminating the life of GPCRs.

  Cell communication and signaling : CCS 20090101

• Estrous cycle influences the expression of neuronal nitric oxide synthase in the hypothalamus and limbic system of female mice.

  BMC neuroscience 20090101

• Guanine nucleotides in the meiotic maturation of starfish oocytes: regulation of the actin cytoskeleton and of Ca(2+) signaling.

  PloS one 20090101

• Drosophila photoreceptors and signaling mechanisms.

  Frontiers in cellular neuroscience 20090101

• DNA binding by Corynebacterium glutamicum TetR-type transcription regulator AmtR.

  BMC molecular biology 20090101

• A Dictyostelium chalone uses G proteins to regulate proliferation.

  BMC biology 20090101

• Hidden chromosome symmetry: in silico transformation reveals symmetry in 2D DNA walk trajectories of 671 chromosomes.

  PloS one 20090101

• Human guanylate binding proteins potentiate the anti-chlamydia effects of interferon-gamma.

  PloS one 20090101

• Pinellia ternata, Citrus reticulata, and their combinational prescription inhibit eosinophil infiltration and airway hyperresponsiveness by suppressing CCR3+ and Th2 cytokines production in the ovalbumin-induced asthma model.

  Mediators of inflammation 20090101

• Positive selection at codon 38 of the human KCNE1 (= minK) gene and sporadic absence of 38Ser-coding mRNAs in Gly38Ser heterozygotes.

  BMC evolutionary biology 20090101

• Genome-wide profile of pleural mesothelioma versus parietal and visceral pleura: the emerging gene portrait of the mesothelioma phenotype.

  PloS one 20090101

• Regulation of MicroRNA Biogenesis: A miRiad of mechanisms.

  Cell communication and signaling : CCS 20090101

• Lipid raft-mediated regulation of G-protein coupled receptor signaling by ligands which influence receptor dimerization: a computational study.

  PloS one 20090101

• Equilibrium and kinetic investigations of the interaction of model platinum(II) complex with DNA constituents in reference to the antitumour activity: complex-formation reactions of [Pd(N,N-diethylethylenediamine)(H2O)2]2+ with ligands of biological significance and displacement reactions of DNA constituents.

  Bioinorganic chemistry and applications 20090101

• The role of relA and spoT in Yersinia pestis KIM5 pathogenicity.

  PloS one 20090101

• On the origin of life in the zinc world: 1. Photosynthesizing, porous edifices built of hydrothermally precipitated zinc sulfide as cradles of life on Earth.

  Biology direct 20090101

• Pharmacotherapy of pediatric and adolescent HIV infection.

  Therapeutics and clinical risk management 20090101

• A differential effect of E. coli toxin-antitoxin systems on cell death in liquid media and biofilm formation.

  PloS one 20090101

• Differential bacterial surface display of peptides by the transmembrane domain of OmpA.

  PloS one 20090101

• Structure and function converge to identify a hydrogen bond in a group I ribozyme active site.

  Angewandte Chemie (International ed. in English) 20090101

• Preparation of group I introns for biochemical studies and crystallization assays by native affinity purification.

  PloS one 20090101

• Glucose absorption and gastric emptying in critical illness.

  Critical care (London, England) 20090101

• Genotoxicity of nano/microparticles in in vitro micronuclei, in vivo comet and mutation assay systems.

  Particle and fibre toxicology 20090101

• 9-(2-C-Cyano-2-deoxy-beta-D-arabino-pentofuranosyl)guanine, a potential antitumor agent against B-lymphoma infected with Kaposi's sarcoma-associated herpesvirus.

  Nucleic acids symposium series (2004) 20090101

• Analysis of an RNA adduct formed from aminophenylnorharman.

  Nucleic acids symposium series (2004) 20090101

• The oxidation of 2'-deoxy-8-oxoguanosine by iodine.

  Nucleic acids symposium series (2004) 20090101

• Identification of gemin5 as a novel 7-methylguanosine cap-binding protein.

  PloS one 20090101

• Mycophenolic acid formulations in adult renal transplantation - update on efficacy and tolerability.

  Therapeutics and clinical risk management 20090101

• Gender-specific modulation of the response to arterial injury by soluble guanylate cyclase α1.

  The open cardiovascular medicine journal 20090101

• FGF4 independent derivation of trophoblast stem cells from the common vole.

  PloS one 20090101

• Glutamate uptake triggers transporter-mediated GABA release from astrocytes.

  PloS one 20090101

• ERG-associated protein with SET domain (ESET)-Oct4 interaction regulates pluripotency and represses the trophectoderm lineage.

  Epigenetics & chromatin 20090101

• Molecular models for intrastrand DNA G-quadruplexes.

  BMC structural biology 20090101

• A man-made ATP-binding protein evolved independent of nature causes abnormal growth in bacterial cells.

  PloS one 20090101

• Initial implementation of a comparative data analysis ontology.

  Evolutionary bioinformatics online 20090101

• Impaired glucose and nutrient absorption in critical illness: is gastric emptying only a piece of the puzzle?

  Critical care (London, England) 20090101

• L-type channel inhibition by CB1 cannabinoid receptors is mediated by PTX-sensitive G proteins and cAMP/PKA in GT1-7 hypothalamic neurons.

  Cell calcium 20090101

• Gene expression analysis of the biocontrol fungus Trichoderma harzianum in the presence of tomato plants, chitin, or glucose using a high-density oligonucleotide microarray.

  BMC microbiology 20090101

• Post-transcriptional control of chloroplast gene expression.

  Gene regulation and systems biology 20090101

• Graves' disease associated with primary systemic sclerosis.

  Orbit (Amsterdam, Netherlands) 20090101

• Functional characterization of N-terminally GFP-tagged GLP-1 receptor.

  Journal of biomedicine & biotechnology 20090101

• The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats.

  Reproductive biology and endocrinology : RB&E 20090101

• 'cAMP sponge': a buffer for cyclic adenosine 3', 5'-monophosphate.

  PloS one 20090101

• Long-term prediction of fish growth under varying ambient temperature using a multiscale dynamic model.

  BMC systems biology 20090101

• The charge-transfer band of an oxidized watson-crick guanosine-cytidine complex.

  Angewandte Chemie (International ed. in English) 20090101

• Predominant membrane localization is an essential feature of the bacterial signal recognition particle receptor.

  BMC biology 20090101

• Activation of adenosine A2B receptors enhances ciliary beat frequency in mouse lateral ventricle ependymal cells.

  Cerebrospinal fluid research 20090101

• Quantifying and resolving multiple vector transformants in S. cerevisiae plasmid libraries.

  BMC biotechnology 20090101

• Tackling the methylome: recent methodological advances in genome-wide methylation profiling.

  Genome medicine 20090101

• Glycine Receptors Caught between Genome and Proteome - Functional Implications of RNA Editing and Splicing.

  Frontiers in molecular neuroscience 20090101

• Homocysteine may contribute to pathogenesis of RNA damage in brains with Alzheimer's disease.

  Neuro-degenerative diseases 20090101

• Evidence for ADAR-induced hypermutation of the Drosophila sigma virus (Rhabdoviridae).

  BMC genetics 20090101

• Identification and expression analysis of ras gene in silkworm, Bombyx mori.

  PloS one 20090101

• Characterization of an engineered human purine nucleoside phosphorylase fused to an anti-her2/neu single chain Fv for use in ADEPT.

  Journal of experimental & clinical cancer research : CR 20090101

• NADPH oxidase expression and production of superoxide by human corneal stromal cells.

  Molecular vision 20090101

• Nuclear factor I-A represses expression of the cell adhesion molecule L1.

  BMC molecular biology 20090101

• Human synthetic lethal inference as potential anti-cancer target gene detection.

  BMC systems biology 20090101

• Proteome-based analysis of serologically defined tumor-associated antigens in cutaneous lymphoma.

  PloS one 20090101

• The repertoire of equine intestinal alpha-defensins.

  BMC genomics 20090101

• Understanding the molecular basis of plant growth promotional effect of Pseudomonas fluorescens on rice through protein profiling.

  Proteome science 20090101

• Divergence of allosteric effects of rapacuronium on binding and function of muscarinic receptors.

  BMC pharmacology 20090101

• Genetic variations in the HGPRT, ITPA, IMPDH1, IMPDH2, and GMPS genes in Japanese individuals.

  Drug metabolism and pharmacokinetics 20090101

• P19 H-ras induces G1/S phase delay maintaining cells in a reversible quiescence state.

  PloS one 20090101

• Mizoribine: a new approach in the treatment of renal disease.

  Clinical & developmental immunology 20090101

• Brain natriuretic peptide in pulmonary arterial hypertension: biomarker and potential therapeutic agent.

  Drug design, development and therapy 20090101

• A new photosensory function for simple photoreceptors, the intrinsically photoresponsive neurons of the sea slug onchidium.

  Frontiers in cellular neuroscience 20090101

• Control of oocyte release by progesterone receptor-regulated gene expression.

  Nuclear receptor signaling 20090101

• A comprehensive review of immunosuppression used for liver transplantation.

  Journal of transplantation 20090101

• The treatment of chronic hepatitis C virus infection in HIV co-infection.

  European journal of medical research 20090101

• Quality, stability, and safety data of packed red cells and plasma processed by gravity separation using a new fully integrated hollow-fibre filter device.

  Advances in hematology 20090101

• Vasopressin in the pediatric cardiac intensive care unit: Myth or reality.

  Annals of pediatric cardiology 20090101

• Immunoregulation through IL-10 gene expression and the fate of cytotoxic T lymphocyte-mediated tumor immunotherapy.

  Indian journal of human genetics 20090101

• Setting the absolute threshold of vision.

  F1000 biology reports 20090101

• Oxidative stress as a mediator of cardiovascular disease.

  Oxidative medicine and cellular longevity 20090101

• Bitopic ligands: all-in-one orthosteric and allosteric.

  F1000 biology reports 20090101

• Endocannabinoid receptor pharmacology.

  Current topics in behavioral neurosciences 20090101

• Tacrolimus ointment in the management of atopic dermatitis.

  Clinical, cosmetic and investigational dermatology 20090101

• Protective effects of solvent fractions of Mentha spicata (L.) leaves evaluated on 4-nitroquinoline-1-oxide induced chromosome damage and apoptosis in mouse bone marrow cells.

  Genetics and molecular biology 20090101

• Assessment of the Potential Role of Tryptophan as the Precursor of Serotonin and Melatonin for the Aged Sleep-wake Cycle and Immune Function: Streptopelia Risoria as a Model.

  International journal of tryptophan research : IJTR 20090101

• Distinct pattern of mutations of conserved regions of TP53 in colorectal cancer patients in the Kashmir population: an emerging high-risk area.

  Ecancermedicalscience 20090101

• Calculation of pKa values of nucleobases and the guanine oxidation products guanidinohydantoin and spiroiminodihydantoin using density functional theory and a polarizable continuum model.

  The journal of physical chemistry. B 20081225

• Probes for narcotic receptor mediated phenomena. 37. Synthesis and opioid binding affinity of the final pair of oxide-bridged phenylmorphans, the ortho- and para-b-isomers and their N-phenethyl analogues, and the synthesis of the N-phenethyl analogues of the ortho- and para-d-isomers.

  Journal of medicinal chemistry 20081225

• Effect of hyperoxidized guanine on DNA primer-template structures: spiroiminodihydantoin leads to strand slippage.

  FEBS letters 20081224

• GAP1(IP4BP)/RASA3 mediates Galphai-induced inhibition of mitogen-activated protein kinase.

  The Journal of biological chemistry 20081219

• In vitro synthesis and characterization of guanosine 3',5'-bis(diphosphate).

  Analytical biochemistry 20081215

• Synthesis of a novel 6,14-epoxymorphinan derivative and its pharmacology.

  Bioorganic & medicinal chemistry letters 20081215

• Simultaneous determination of nucleobases, nucleosides and saponins in Panax notoginseng using multiple columns high performance liquid chromatography.

  Journal of pharmaceutical and biomedical analysis 20081215

• The specific activation of TRPC4 by Gi protein subtype.

  Biochemical and biophysical research communications 20081212

• 8-Nitroguanosines as chemical probes of the protein S-guanylation.

  Chemical communications (Cambridge, England) 20081207

• Differential coupling of the human cannabinoid receptors hCB1R and hCB2R to the G-protein G(alpha)i2beta1gamma2.

  Neuroscience letters 20081205

• Muscarinic receptor changes in the gerbil thalamus during aging.

  Brain research 20081203

• Functional coupling of mu-receptor-Galphai-tethered proteins in AtT20 cells.

  Neuroreport 20081203

• Enhancement of mucosal immune responses by intranasal co-delivery of Newcastle disease vaccine plus CpG oligonucleotide in SPF chickens in vivo.

  Research in veterinary science 20081201

• Angiotensin II type 1 receptor blocker ameliorates uncoupled endothelial nitric oxide synthase in rats with experimental diabetic nephropathy.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081201

• Antioxidative effects of statins.

  Archives of toxicology 20081201

• Antipsychotic-induced alterations in CB1 receptor-mediated G-protein signaling and in vivo pharmacology in rats.

  Neuropharmacology 20081201

• Nuclear factor-kappaB mediates the inhibitory effects of tumor necrosis factor-alpha on growth hormone-inducible gene expression in liver.

  Endocrinology 20081201

• Identification and characterization of NDT 9513727 [N,N-bis(1,3-benzodioxol-5-ylmethyl)-1-butyl-2,4-diphenyl-1H-imidazole-5-methanamine], a novel, orally bioavailable C5a receptor inverse agonist.

  The Journal of pharmacology and experimental therapeutics 20081201

• A novel delta opioid receptor antagonist, SoRI-9409, produces a selective and long-lasting decrease in ethanol consumption in heavy-drinking rats.

  Biological psychiatry 20081201

• Mechanisms of EHD/RME-1 protein function in endocytic transport.

  Traffic (Copenhagen, Denmark) 20081201

• Binding of the novel radioligand [(3)H]UFP-101 to recombinant human and native rat nociceptin/orphanin FQ receptors.

  Naunyn-Schmiedeberg's archives of pharmacology 20081201

• WAY100635 prevents the changes induced by fluoxetine upon the 5-HT1A receptor functionality.

  Neuropharmacology 20081201

• Inhibitory effects of epoxyeicosatrienoic acids on volume-activated chloride channels in rat mesenteric arterial smooth muscle.

  Prostaglandins & other lipid mediators 20081201

• Identification and functional characterization of allosteric agonists for the G protein-coupled receptor FFA2.

  Molecular pharmacology 20081201

• ARAP1 regulates endocytosis of EGFR.

  Traffic (Copenhagen, Denmark) 20081201

• Rel/NF-kappaB family member RelA regulates NK1.1- to NK1.1+ transition as well as IL-15-induced expansion of NKT cells.

  European journal of immunology 20081201

• Phosphorylation of nucleosides and nucleotides with inorganic monoimido-cyclo-triphosphate.

  Chemical & pharmaceutical bulletin 20081201

• [In-vitro screening of psychoactive drugs to prevent abuses].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20081201

• Role of iNO in the modulation of pulmonary vascular resistance.

  Journal of perinatology : official journal of the California Perinatal Association 20081201

• The stringent response and cell cycle arrest in Escherichia coli.

  PLoS genetics 20081201

• Chronic voluntary ethanol intake hypersensitizes 5-HT(1A) autoreceptors in C57BL/6J mice.

  Journal of neurochemistry 20081201

• ABCD of the phosphodiesterase family: interaction and differential activity in COPD.

  International journal of chronic obstructive pulmonary disease 20081201

• Mycophenolate mofetil for myasthenia gravis: a clear and present controversy.

  Neuropsychiatric disease and treatment 20081201

• Virologic, serologic, and biochemical outcomes through 2 years of treatment with entecavir and lamivudine in nucleoside-naïve Chinese patients with chronic hepatitis B: a randomized, multicenter study.

  Hepatology international 20081201

• Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics.

  Journal of molecular biology 20081121

• Crystal structure of tRNA N2,N2-guanosine dimethyltransferase Trm1 from Pyrococcus horikoshii.

  Journal of molecular biology 20081121

• High resolution mass spectrometry for studying the interactions of cisplatin with oligonucleotides.

  Inorganic chemistry 20081117

• Genetic and biochemical analysis of yeast and human cap trimethylguanosine synthase: functional overlap of 2,2,7-trimethylguanosine caps, small nuclear ribonucleoprotein components, pre-mRNA splicing factors, and RNA decay pathways.

  The Journal of biological chemistry 20081114

• Inactive and active states of the interferon-inducible resistance GTPase, Irga6, in vivo.

  The Journal of biological chemistry 20081114

• The antiherpetic drug acyclovir inhibits HIV replication and selects the V75I reverse transcriptase multidrug resistance mutation.

  The Journal of biological chemistry 20081114

• A naloxonazine sensitive (mu1 receptor) mechanism in the parabrachial nucleus modulates eating.

  Brain research 20081113

• Polyphosphatase activity of CthTTM, a bacterial triphosphate tunnel metalloenzyme.

  The Journal of biological chemistry 20081107

• Inhibition of dicing of guanosine-rich shRNAs by quadruplex-binding compounds.

  Chembiochem : a European journal of chemical biology 20081103

• Mycophenolic acid inhibits cell proliferation and extracellular matrix synthesis in rat vascular smooth muscle cells through direct and indirect inhibition of cellular reactive oxygen species.

  The Journal of surgical research 20081101

• A molecular model of a putative substrate releasing conformation of multidrug resistance protein 5 (MRP5).

  European journal of medicinal chemistry 20081101

• Time-limited hyporesponsiveness to inhaled nitric oxide and pulmonary phosphodiesterase activity in endotoxemic rats.

  The Journal of surgical research 20081101

• G protein coupling and signaling pathway activation by m1 muscarinic acetylcholine receptor orthosteric and allosteric agonists.

  The Journal of pharmacology and experimental therapeutics 20081101

• N-arachidonyl maleimide potentiates the pharmacological and biochemical effects of the endocannabinoid 2-arachidonylglycerol through inhibition of monoacylglycerol lipase.

  The Journal of pharmacology and experimental therapeutics 20081101

• Metabolomic analyses of body fluids after subchronic manganese inhalation in rhesus monkeys.

  Toxicological sciences : an official journal of the Society of Toxicology 20081101

• Morphine desensitization, internalization, and down-regulation of the mu opioid receptor is facilitated by serotonin 5-hydroxytryptamine2A receptor coactivation.

  Molecular pharmacology 20081101

• Characteristics and modifying factors of asbestos-induced oxidative DNA damage.

  Cancer science 20081101

• In vitro nonenzymatic glycation of guanosine 5'-triphosphate by dihydroxyacetone phosphate.

  Analytical and bioanalytical chemistry 20081101

• Renal proximal tubules from old Fischer 344 rats grow into epithelial cells in cultures and exhibit increased oxidative stress and reduced D1 receptor function.

  American journal of physiology. Cell physiology 20081101

• Advanced glycation end products of DNA: quantification of N2-(1-Carboxyethyl)-2'-deoxyguanosine in biological samples by liquid chromatography electrospray ionization tandem mass spectrometry.

  Chemical research in toxicology 20081101

• Effect of NMSO3 treatment in a murine model of human metapneumovirus infection.

  The Journal of general virology 20081101

• Bryostatin-5 blocks stromal cell-derived factor-1 induced chemotaxis via desensitization and down-regulation of cell surface CXCR4 receptors.

  Cancer research 20081101

• Influence of cyclic guanosine 3',5' monophosphate modulators on muscle contraction of rat aortas.

  Saudi medical journal 20081101

• S-nitrosylation of surfactant protein-D controls inflammatory function.

  PLoS biology 20081101

• Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2-deficient mice.

  Genes to cells : devoted to molecular & cellular mechanisms 20081101

• rac regulates its effector phospholipase Cgamma2 through interaction with a split pleckstrin homology domain.

  The Journal of biological chemistry 20081031

• Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation.

  Proceedings of the National Academy of Sciences of the United States of America 20081028

• Protein kinase G-dependent cardioprotective mechanism of phosphodiesterase-5 inhibition involves phosphorylation of ERK and GSK3beta.

  The Journal of biological chemistry 20081024

• A novel mechanism of G protein-coupled receptor functional selectivity. Muscarinic partial agonist McN-A-343 as a bitopic orthosteric/allosteric ligand.

  The Journal of biological chemistry 20081024

• Effect of the ribose versus 2'-deoxyribose residue on the metal ion-binding properties of purine nucleotides.

  Dalton transactions (Cambridge, England : 2003) 20081021

• Innate immunity in Caenorhabditis elegans is regulated by neurons expressing NPR-1/GPCR.

  Science (New York, N.Y.) 20081017

• A simple cytosine to G-clamp nucleobase substitution enables chiral gamma-PNAs to invade mixed-sequence double-helical B-form DNA.

  Chembiochem : a European journal of chemical biology 20081013

• Small molecule-induced allosteric activation of the Vibrio cholerae RTX cysteine protease domain.

  Science (New York, N.Y.) 20081010

• Antinociceptive effects of intracerebroventricular administration of guanine-based purines in mice: evidences for the mechanism of action.

  Brain research 20081009

• Recognition of the activated states of Galpha13 by the rgRGS domain of PDZRhoGEF.

  Structure (London, England : 1993) 20081008

• mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity.

  Molecular psychiatry 20081001

• Inhibitory effects of quercetin derivatives on phosphodiesterase isozymes and high-affinity [(3) H]-rolipram binding in guinea pig tissues.

  Investigational new drugs 20081001

• In vivo characterization of (-)(-)MCL-144 and (+)(-)MCL-193: isomeric, bivalent ligands with mu/kappa agonist properties.

  Neurochemical research 20081001

• Structural motifs of importance for the constitutive activity of the orphan 7TM receptor EBI2: analysis of receptor activation in the absence of an agonist.

  Molecular pharmacology 20081001

• Genetic evidence for the essential role of PfNT1 in the transport and utilization of xanthine, guanine, guanosine and adenine by Plasmodium falciparum.

  Molecular and biochemical parasitology 20081001

• Electroanalytical study of proflavine intercalation in 5-methyl or inosine-containing amplicons.

  Analytical and bioanalytical chemistry 20081001

• Serotonin increases GABA release in rat entorhinal cortex by inhibiting interneuron TASK-3 K+ channels.

  Molecular and cellular neurosciences 20081001

• Dopamine D1 receptor inhibition of NMDA receptor currents mediated by tyrosine kinase-dependent receptor trafficking in neonatal rat striatum.

  The Journal of physiology 20081001

• Changes in the rewarding effects induced by tramadol and its active metabolite M1 after sciatic nerve injury in mice.

  Psychopharmacology 20081001

• Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m2 2G:A pairs.

  RNA (New York, N.Y.) 20081001

• TRAMP-mediated RNA surveillance prevents spurious entry of RNAs into the Schizosaccharomyces pombe siRNA pathway.

  Nature structural & molecular biology 20081001

• Labelling and biological evaluation of [(11)C]methoxy-Sch225336: a radioligand for the cannabinoid-type 2 receptor.

  Nuclear medicine and biology 20081001

• Pharmacokinetics of guanosine in rats following intravenous or intramuscular administration of a 1:1 mixture of guanosine and acriflavine, a potential antitumor agent.

  Archives of pharmacal research 20081001

• Receptor-mediated changes at the myristoylated amino terminus of Galpha(il) proteins.

  Biochemistry 20080930

• Arabidopsis nucleoside diphosphate kinase-2 as a plant GTPase activating protein.

  BMB reports 20080930

• Crystal structure of the Thermus thermophilus 16 S rRNA methyltransferase RsmC in complex with cofactor and substrate guanosine.

  The Journal of biological chemistry 20080926

• Density functional theory calculations of hydrogen-bond-mediated NMR J coupling in the solid state.

  Journal of the American Chemical Society 20080924

• Activating parabrachial cannabinoid CB1 receptors selectively stimulates feeding of palatable foods in rats.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080924

• Purification and mass spectrometric analysis of the kappa opioid receptor.

  Brain research 20080916

• Structure of the 1,N2-ethenodeoxyguanosine adduct opposite cytosine in duplex DNA: Hoogsteen base pairing at pH 5.2.

  Chemical research in toxicology 20080915

• N2-functionalized blue luminescent guanosines by 2,2'-dipyridylamino and 2-(2'-pyridyl)benzimidazolyl chelate groups and their interactions with Zn(II) ions.

  Inorganic chemistry 20080915

• Redesigned tetrads with altered hydrogen bonding patterns enable programming of quadruplex topologies.

  Chemical communications (Cambridge, England) 20080914

• Structures of substrate- and inhibitor-bound adenosine deaminase from a human malaria parasite show a dramatic conformational change and shed light on drug selectivity.

  Journal of molecular biology 20080912

• Effects of sample preparation methods on the quantification of nucleosides in natural and cultured Cordyceps.

  Journal of pharmaceutical and biomedical analysis 20080910

• Oxidized phospholipid inhibition of toll-like receptor (TLR) signaling is restricted to TLR2 and TLR4: roles for CD14, LPS-binding protein, and MD2 as targets for specificity of inhibition.

  The Journal of biological chemistry 20080905

• Interconversion of the cis-5R,6S- and trans-5R,6R-thymine glycol lesions in duplex DNA.

  Journal of the American Chemical Society 20080903

• Crystal structure of archaeal tRNA(m(1)G37)methyltransferase aTrm5.

  Proteins 20080901

• Studies on DNA-binding selectivity of WRKY transcription factors lend structural clues into WRKY-domain function.

  Plant molecular biology 20080901

• Functional reconstitution of the human chemokine receptor CXCR4 with G(i)/G (o)-proteins in Sf9 insect cells.

  Naunyn-Schmiedeberg's archives of pharmacology 20080901

• Expression profiling of four RelA/SpoT-like proteins, homologues of bacterial stringent factors, in Arabidopsis thaliana.

  Planta 20080901

• Carbon monoxide and nitric oxide mediate cytoskeletal reorganization in microvascular cells via vasodilator-stimulated phosphoprotein phosphorylation: evidence for blunted responsiveness in diabetes.

  Diabetes 20080901

• Evidence for interindividual heterogeneity in the glucose gradient across the human red blood cell membrane and its relationship to hemoglobin glycation.

  Diabetes 20080901

• Effect of Maillard reacted peptides on human salt taste and the amiloride-insensitive salt taste receptor (TRPV1t).

  Chemical senses 20080901

• Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6.

  The Journal of physiology 20080901

• Expression and hepatobiliary transport characteristics of the concentrative and equilibrative nucleoside transporters in sandwich-cultured human hepatocytes.

  American journal of physiology. Gastrointestinal and liver physiology 20080901

• Synthesis and application of a new 2',3'-isopropylidene guanosine substituted cap analog.

  Bioorganic & medicinal chemistry letters 20080901

• Process research on the preparation of DMT protected 2'-O-methoxyethylguanosine for oligonucleotide synthesis in therapeutic applications.

  Nucleosides, nucleotides & nucleic acids 20080901

• Involvement of kappa opioid receptors in the inhibition of receptor desensitization and PKC activation induced by repeated morphine treatment.

  The Journal of pharmacy and pharmacology 20080901

• Effects of mycophenolic acid on human fibroblast proliferation, migration and adhesion in vitro and in vivo.

  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080901

• Effect of COPD treatments on MRP1-mediated transport in bronchial epithelial cells.

  International journal of chronic obstructive pulmonary disease 20080901

• [Quantitative analysis of nucleotide mixtures with terahertz time domain spectroscopy].

  Guang pu xue yu guang pu fen xi = Guang pu 20080901

• Cellular and biochemical actions of melatonin which protect against free radicals: role in neurodegenerative disorders.

  Current neuropharmacology 20080901

• Determination of nucleotides in infant formula by ion-exchange liquid chromatography.

  Journal of agricultural and food chemistry 20080827

• Rab3GEP is the non-redundant guanine nucleotide exchange factor for Rab27a in melanocytes.

  The Journal of biological chemistry 20080822

• Mechanisms of lumbrokinase in protection of cerebral ischemia.

  European journal of pharmacology 20080820

• The RNA acetyltransferase driven by ATP hydrolysis synthesizes N4-acetylcytidine of tRNA anticodon.

  The EMBO journal 20080820

• Overexpression of human OGG1 in mammalian cells decreases ultraviolet A induced mutagenesis.

  Cancer letters 20080818

• A flexible loop as a functional element in the catalytic mechanism of nucleoside hydrolase from Trypanosoma vivax.

  The Journal of biological chemistry 20080808

• Evidence for two distinct Mg2+ binding sites in G(s alpha) and G(i alpha1) proteins.

  Biochemical and biophysical research communications 20080808

• Human CHN1 mutations hyperactivate alpha2-chimaerin and cause Duane's retraction syndrome.

  Science (New York, N.Y.) 20080808

• Formation of tricyclic [4.3.3.0] adducts between 8-oxoguanosine and tyrosine under conditions of oxidative DNA-protein cross-linking.

  Journal of the American Chemical Society 20080806

• Characterization of umami receptor and coupling G protein in mouse taste cells.

  Neuroreport 20080806

• Guanosine and its modulatory effects on the glutamatergic system.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20080801

• HPLC-fluorescence assay for acyclovir in children.

  Biomedical chromatography : BMC 20080801

• Dysregulation of nociceptin/orphanin FQ activity in the amygdala is linked to excessive alcohol drinking in the rat.

  Biological psychiatry 20080801

• Molecular mechanisms of PLD function in membrane traffic.

  Traffic (Copenhagen, Denmark) 20080801

• Investigation into A antigen expression on O2 heterozygous group O-labeled red blood cell units.

  Transfusion 20080801

• Caspase cleavage of phospholipase D1 in vitro alters its regulation and reveals a novel property of the 'loop' region.

  Biochimica et biophysica acta 20080801

• Suppression of grasshopper sound production by nitric oxide-releasing neurons of the central complex.

  Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20080801

• Conformationally restricted nucleotides as a probe of structure-function relationships in RNA.

  RNA (New York, N.Y.) 20080801

• Regulation of the RelA (p65) transactivation domain.

  Biochemical Society transactions 20080801

• Neuropeptide Y receptors in primary human brain tumors: overexpression in high-grade tumors.

  Journal of neuropathology and experimental neurology 20080801

• Some selective serotonin reuptake inhibitors inhibit dynamin I guanosine triphosphatase (GTPase).

  Biological & pharmaceutical bulletin 20080801

• High-precision, whole-genome sequencing of laboratory strains facilitates genetic studies.

  PLoS genetics 20080801

• Decrease of D2 receptor binding but increase in D2-stimulated G-protein activation, dopamine transporter binding and behavioural sensitization in brains of mice treated with a chronic escalating dose 'binge' cocaine administration paradigm.

  The European journal of neuroscience 20080801

• Photophysical characterization and photodynamic activity of metallo 5-(4-(trimethylammonium)phenyl)-10,15,20-tris(2,4,6-trimethoxyphenyl)porphyrin in homogeneous and biomimetic media.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20080801

• Coordinate regulation of G protein signaling via dynamic interactions of receptor and GAP.

  PLoS computational biology 20080801

• An enzymatic atavist revealed in dual pathways for water activation.

  PLoS biology 20080801

• Dendritic cells stimulated with cytidine-phosphate-guanosine oligodeoxynucleotides and interferon-alpha-expressing tumor cells effectively reduce outgrowth of established tumors in vivo.

  Cancer science 20080801

• A preliminary report of the dopamine receptor D(4) and the dopamine transporter 1 gene polymorphism and its association with attention deficit hyperactivity disorder.

  Neuropsychiatric disease and treatment 20080801

• Pegylated interferon 2a and 2b in combination with ribavirin for the treatment of chronic hepatitis C in HIV infected patients.

  Therapeutics and clinical risk management 20080801

• G protein activation by the leukotriene B4 receptor dimer. Evidence for an absence of trans-activation.

  The Journal of biological chemistry 20080725

• Identification of farnesyl pyrophosphate and N-arachidonylglycine as endogenous ligands for GPR92.

  The Journal of biological chemistry 20080725

• Human polynucleotide phosphorylase reduces oxidative RNA damage and protects HeLa cell against oxidative stress.

  Biochemical and biophysical research communications 20080725

• Changes in conformational dynamics of mRNA upon AtGRP7 binding studied by fluorescence correlation spectroscopy.

  Journal of the American Chemical Society 20080723

• The 2'-hydroxyl group of the guanosine nucleophile donates a functionally important hydrogen bond in the tetrahymena ribozyme reaction.

  Biochemistry 20080722

• 13C relaxation studies of the DNA target sequence for hhai methyltransferase reveal unique motional properties.

  Biochemistry 20080722

• Discovery of potent CCR4 antagonists: Synthesis and structure-activity relationship study of 2,4-diaminoquinazolines.

  Bioorganic & medicinal chemistry 20080715

• Superior removal of hydantoin lesions relative to other oxidized bases by the human DNA glycosylase hNEIL1.

  Biochemistry 20080708

• Effects of the G(-656)A variant on CREB1 promoter activity in a glial cell line: interactions with gonadal steroids and stress.

  American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20080705

• Photocleavable initiator nucleotide substrates for an aldolase ribozyme.

  The Journal of organic chemistry 20080704

• Synthesis of a stabilized version of the imidazolone DNA lesion.

  Chembiochem : a European journal of chemical biology 20080702

• Structural basis of thiamine pyrophosphate analogues binding to the eukaryotic riboswitch.

  Journal of the American Chemical Society 20080702

• Celecoxib-induced growth inhibition in SW480 colon cancer cells is associated with activation of protein kinase G.

  Molecular carcinogenesis 20080701

• TRPC5 channels undergo changes in gating properties during the activation-deactivation cycle.

  Journal of cellular physiology 20080701

• Norepinephrine-mediated regulation of 5HT1 receptor functioning in human platelets.

  Neurochemical research 20080701

• Silencing genes in the kidney: antisense or RNA interference?

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080701

• Synthesis of 1-beta-D-ribofuranosyl-3-ethynyl-[1,2,4]triazole and its in vitro and in vivo efficacy against Hantavirus.

  Antiviral research 20080701

• miRNAs at the heart of the matter.

  Journal of molecular medicine (Berlin, Germany) 20080701

• High yield purification of soluble guanylate cyclase from bovine lung.

  Protein expression and purification 20080701

• Novobiocin inhibits the self-splicing of the primary transcripts of T4 phage thymidylate synthase gene.

  Molecular and cellular biochemistry 20080701

• Conformational change of the transmembrane helices II and IV of metabotropic glutamate receptor involved in G protein activation.

  Journal of neurochemistry 20080701

• Disruption of a Plasmodium falciparum cyclic nucleotide phosphodiesterase gene causes aberrant gametogenesis.

  Molecular microbiology 20080701

• Microfabricated channel array electrophoresis for characterization and screening of enzymes using RGS-G protein interactions as a model system.

  Analytical chemistry 20080701

• Effects of Delta9-tetrahydrocannabivarin on [35S]GTPgammaS binding in mouse brain cerebellum and piriform cortex membranes.

  British journal of pharmacology 20080701

• Long-term fasting decreases mitochondrial avian UCP-mediated oxygen consumption in hypometabolic king penguins.

  American journal of physiology. Regulatory, integrative and comparative physiology 20080701

• ATP/UTP activate cation-permeable channels with TRPC3/7 properties in rat cardiomyocytes.

  American journal of physiology. Heart and circulatory physiology 20080701

• High-content assay to study protein prenylation.

  Journal of biomolecular screening 20080701

• Mutation in the rel gene of Sorangium cellulosum affects morphological and physiological differentiation.

  Molecular microbiology 20080701

• Inhibition of fatty acid amide hydrolase and cyclooxygenase-2 increases levels of endocannabinoid related molecules and produces analgesia via peroxisome proliferator-activated receptor-alpha in a model of inflammatory pain.

  Neuropharmacology 20080701

• Membrane potential shifts caused by diffusible guidance signals direct growth-cone turning.

  Nature neuroscience 20080701

• A general method for phasing novel complex RNA crystal structures without heavy-atom derivatives.

  Acta crystallographica. Section D, Biological crystallography 20080701

• The role of G proteins in thromospondin-1-induced vascular smooth muscle cell migration.

  Surgery 20080701

• Design, synthesis, and actions of a novel chimeric natriuretic peptide: CD-NP.

  Journal of the American College of Cardiology 20080701

• Contribution of active and inactive states of the human 5-HT4d receptor to the functional activities of 5-HT4-receptor agonists.

  Journal of pharmacological sciences 20080701

• Activation of protein kinase G Increases the expression of p21CIP1, p27KIP1, and histidine triad protein 1 through Sp1.

  Cancer research 20080701

• Kinetic modeling of the assembly, dynamic steady state, and contraction of the FtsZ ring in prokaryotic cytokinesis.

  PLoS computational biology 20080701

• Brevetoxin forms covalent DNA adducts in rat lung following intratracheal exposure.

  Environmental health perspectives 20080701

• Miscoding properties of 6alpha- and 6beta-diastereoisomers of the N(2)-(estradiol-6-yl)-2'-deoxyguanosine DNA adduct by Y-family human DNA polymerases.

  Biochemistry 20080624

• Systematic deletion of the adenovirus-associated RNAI terminal stem reveals a surprisingly active RNA inhibitor of double-stranded RNA-activated protein kinase.

  The Journal of biological chemistry 20080620

• Liquid crystalline phase of G-tetrad DNA for NMR study of detergent-solubilized proteins.

  Journal of the American Chemical Society 20080618

• Differential induction of nitric oxide, degranulation, and oxidative burst activities in response to microbial agonist stimulations in monocytes and heterophils from young commercial turkeys.

  Veterinary immunology and immunopathology 20080615

• Expression and characterization of the human alpha 2B-adrenoceptor in a vascular smooth muscle cell line.

  European journal of pharmacology 20080610

• Morphine-nicotine interaction in conditioned place preference in mice after chronic nicotine exposure.

  European journal of pharmacology 20080610

• Synthesis of hydrophobic derivatives of the G/\C base for rosette nanotube self-assembly in apolar media.

  The Journal of organic chemistry 20080606

• Functional circularity of legitimate Qbeta replicase templates.

  Journal of molecular biology 20080606

• Interactions of guanine and guanosine hydrates with quinones: a laser flash photolysis and magnetic field effect study.

  The journal of physical chemistry. A 20080605

• Analyzing and modeling the inhibitory effect of phosphatidic acid on the GTP-gamma-S binding activity of Goalpha.

  Proteins 20080601

• Stacking efficiency and flexibility analysis of aromatic amino acids in cap-binding proteins.

  Proteins 20080601

• Antibodies that identify only the active conformation of G(i) family G protein alpha subunits.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080601

• Simple HPLC-UV determination of nucleosides and its application to the authentication of Cordyceps and its allies.

  Biomedical chromatography : BMC 20080601

• Assessment of nerve stimulation-induced release of purines from mouse kidneys by tandem mass spectrometry.

  The Journal of pharmacology and experimental therapeutics 20080601

• Pharmacological assessment of m1 muscarinic acetylcholine receptor-gq/11 protein coupling in membranes prepared from postmortem human brain tissue.

  The Journal of pharmacology and experimental therapeutics 20080601

• Peculiar mechanistic and structural features of the carboplatin-cytochrome c system revealed by ESI-MS analysis.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20080601

• Insulin-like growth factor-1 restores erectile function in aged rats: modulation the integrity of smooth muscle and nitric oxide-cyclic guanosine monophosphate signaling activity.

  The journal of sexual medicine 20080601

• GTP avoidance in Tetrahymena thermophila requires tyrosine kinase activity, intracellular calcium, NOS, and guanylyl cyclase.

  Purinergic signalling 20080601

• Reciprocal inhibition of G-protein signaling is induced by CB(1) cannabinoid and GABA(B) receptor interactions in rat hippocampal membranes.

  Neurochemistry international 20080601

• Characterization of phosphate-containing metabolites by calcium adduction and electron capture dissociation.

  Journal of the American Society for Mass Spectrometry 20080601

• A purine-selective nucleobase/nucleoside transporter in PK15NTD cells.

  American journal of physiology. Regulatory, integrative and comparative physiology 20080601

• Characterization of Aquifex aeolicus 4-diphosphocytidyl-2C-methyl-d-erythritol kinase - ligand recognition in a template for antimicrobial drug discovery.

  The FEBS journal 20080601

• Nucleoside composition of Heloderma venoms.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20080601

• Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpS.

  RNA (New York, N.Y.) 20080601

• Oxidative stress impairs the repair of oxidative DNA base modifications in human skin fibroblasts and melanoma cells.

  DNA repair 20080601

• Role of oxidative stress in high glucose-induced decreased expression of Gialpha proteins and adenylyl cyclase signaling in vascular smooth muscle cells.

  American journal of physiology. Heart and circulatory physiology 20080601

• Recruitment of beta-arrestin2 to the dopamine D2 receptor: insights into anti-psychotic and anti-parkinsonian drug receptor signaling.

  Neuropharmacology 20080601

• Interactions of nucleosides with CrO(4) (2-) and Cr(3+) as studied by electrospray ionization mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20080601

• Kinetic characterization of the first step of the ribozyme-catalyzed trans excision-splicing reaction.

  The FEBS journal 20080601

• Metabonomics in cancer diagnosis: mass spectrometry-based profiling of urinary nucleosides from breast cancer patients.

  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20080601

• TLR Ligand-Induced Type I IFNs Affect Thymopoiesis.

  Journal of immunology (Baltimore, Md. : 1950) 20080601

• Analysis of the neuroinflammatory response to TLR7 stimulation in the brain: comparison of multiple TLR7 and/or TLR8 agonists.

  Journal of immunology (Baltimore, Md. : 1950) 20080601

• The spinal antinociceptive effects of endomorphins in rats: behavioral and G protein functional studies.

  Anesthesia and analgesia 20080601

• High-throughput screening of novel antagonists on melanin-concentrating hormone receptor-1.

  Acta pharmacologica Sinica 20080601

• Pharmacological characterization of alpha2D-adrenergic receptor-mediated [35S]GTPgammaS binding in rat cerebral cortical membranes.

  Pharmacological research 20080601

• Downregulation of the Escherichia coli guaB promoter by FIS.

  Microbiology (Reading, England) 20080601

• Gametogenesis in malaria parasites is mediated by the cGMP-dependent protein kinase.

  PLoS biology 20080601

• A 1,536-well [(35)S]GTPgammaS scintillation proximity binding assay for ultra-high-throughput screening of an orphan galphai-coupled GPCR.

  Assay and drug development technologies 20080601

• Concepts of neural nitric oxide-mediated transmission.

  The European journal of neuroscience 20080601

• Group II intron protein localization and insertion sites are affected by polyphosphate.

  PLoS biology 20080601

• A robust and high-capacity [(35)S]GTPgammaS binding assay for determining antagonist and inverse agonist pharmacological parameters of histamine H(3) receptor ligands.

  Assay and drug development technologies 20080601

• Neurotrophic effects of extracellular guanosine.

  Nucleosides, nucleotides & nucleic acids 20080601

• Metabolism and distribution of guanosine given intraperitoneally: implications for spinal cord injury.

  Nucleosides, nucleotides & nucleic acids 20080601

• Electrochemical Investigation of oligonucleotide-DNA hybridization on poly(4-methoxyphenethylamine).

  International journal of molecular sciences 20080601

• Tea polyphenols and their roles in cancer prevention and chemotherapy.

  International journal of molecular sciences 20080601

• Key labeling technologies to tackle sizeable problems in RNA structural biology.

  International journal of molecular sciences 20080601

• Crystal structure of Escherichia coli MazG, the regulator of nutritional stress response.

  The Journal of biological chemistry 20080530

• Quantum dot nanocrystals having guanosine imprinted nanoshell for DNA recognition.

  Talanta 20080530

• Guanosine promotes B16F10 melanoma cell differentiation through PKC-ERK 1/2 pathway.

  Chemico-biological interactions 20080528

• Rv2131c from Mycobacterium tuberculosis is a CysQ 3'-phosphoadenosine-5'-phosphatase.

  Biochemistry 20080527

• Characterization of the Arabidopsis heterotrimeric G protein.

  The Journal of biological chemistry 20080516

• Energization-dependent endogenous activation of proton conductance in skeletal muscle mitochondria.

  The Biochemical journal 20080515

• Synthesis and biochemical application of 2'-O-methyl-3'-thioguanosine as a probe to explore group I intron catalysis.

  Bioorganic & medicinal chemistry 20080515

• Tonic and stimulus-evoked nitric oxide production in the mouse olfactory bulb.

  Neuroscience 20080515

• Simultaneous determination of aciclovir, ganciclovir, and penciclovir in human plasma by high-performance liquid chromatography with fluorescence detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080515

• Fhit-deficient hematopoietic stem cells survive hydroquinone exposure carrying precancerous changes.

  Cancer research 20080515

• Characterization of an orphan G protein-coupled receptor, GPR20, that constitutively activates Gi proteins.

  The Journal of biological chemistry 20080509

• Unexpected suppression of neuronal G protein-activated, inwardly rectifying K+ current by common phospholipase C inhibitor.

  Neuroscience letters 20080509

• Degradation of bidentate-coordinated platinum(II)-based DNA intercalators by reduced L-glutathione.

  Journal of medicinal chemistry 20080508

• Regulator of G-protein signaling subtype 4 mediates antihypertrophic effect of locally secreted natriuretic peptides in the heart.

  Circulation 20080506

• Cisplatin-DNA adduct formation in patients treated with cisplatin-based chemoradiation: lack of correlation between normal tissues and primary tumor.

  Cancer chemotherapy and pharmacology 20080501

• Agonist and antagonist properties of antipsychotics at human dopamine D4.4 receptors: G-protein activation and K+ channel modulation in transfected cells.

  The international journal of neuropsychopharmacology 20080501

• Kinetic and mutational analysis of the Trypanosoma brucei NBT1 nucleobase transporter expressed in Saccharomyces cerevisiae reveals structural similarities between ENT and MFS transporters.

  International journal for parasitology 20080501

• Effects of chronic treatment with citalopram on cannabinoid and opioid receptor-mediated G-protein coupling in discrete rat brain regions.

  Psychopharmacology 20080501

• Allosteric ligands for the corticotropin releasing factor type 1 receptor modulate conformational states involved in receptor activation.

  Molecular pharmacology 20080501

• Suppression of NO production and 8-nitroguanosine formation by phenol-containing endocrine-disrupting chemicals in LPS-stimulated macrophages: involvement of estrogen receptor-dependent or -independent pathways.

  Nitric oxide : biology and chemistry 20080501

• Endogenous regulators of G protein signaling differentially modulate full and partial mu-opioid agonists at adenylyl cyclase as predicted by a collision coupling model.

  Molecular pharmacology 20080501

• PMA counteracts G protein actions on CaV2.2 channels in rat sympathetic neurons.

  Archives of biochemistry and biophysics 20080501

• 17beta-Oestradiol stimulation of G-proteins in aged and Alzheimer's human brain: comparison with phytoestrogens.

  Journal of neuroendocrinology 20080501

• Molecular modeling and dynamics simulations of PNP from Streptococcus agalactiae.

  Bioorganic & medicinal chemistry 20080501

• Supersensitivity to mu-opioid receptor-mediated inhibition of the adenylyl cyclase pathway involves pertussis toxin-resistant Galpha protein subunits.

  Neuropharmacology 20080501

• A cation-directed switch of intermolecular spin-spin interaction of guanosine derivatives functionalized with open-shell units.

  Organic letters 20080501

• A coarse-grained biophysical model of E. coli and its application to perturbation of the rRNA operon copy number.

  PLoS computational biology 20080501

• Human atrial natriuretic peptide suppresses torsades de pointes in rabbits.

  Circulation journal : official journal of the Japanese Circulation Society 20080501

• The acidic tumor microenvironment promotes the reconversion of nitrite into nitric oxide: towards a new and safe radiosensitizing strategy.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20080501

• Direct effects of riluzole on 5-hydroxytryptamine (5-HT)3 receptor-activated ion currents in NCB-20 neuroblastoma cells.

  Journal of pharmacological sciences 20080501

• Separation properties of novel and commercial polar stationary phases in hydrophilic interaction and reversed-phase liquid chromatography mode.

  Journal of separation science 20080501

• Rapid changes in hippocampal CA1 pyramidal cell function via pre- as well as postsynaptic membrane mineralocorticoid receptors.

  The European journal of neuroscience 20080501

• LPK-26, a novel kappa-opioid receptor agonist with potent antinociceptive effects and low dependence potential.

  European journal of pharmacology 20080428

• Constitutive activity of the cannabinoid CB1 receptor regulates the function of co-expressed Mu opioid receptors.

  The Journal of biological chemistry 20080425

• Direct evidence for the involvement of endogenous beta-endorphin in the suppression of the morphine-induced rewarding effect under a neuropathic pain-like state.

  Neuroscience letters 20080425

• A Pneumocystis carinii group I intron-derived ribozyme utilizes an endogenous guanosine as the first reaction step nucleophile in the trans excision-splicing reaction.

  Biochemistry 20080422

• 2'-Deoxyimmunosine: stereoselective synthesis, base pairing and duplex stability of oligonucleotides containing 8-oxo-7-thiaguanine.

  Organic & biomolecular chemistry 20080421

• Mutagenicity of 8-nitroguanosine, a product of nitrative nucleoside modification by reactive nitrogen oxides, in mammalian cells.

  Cancer letters 20080418

• An exploration of mechanisms for the transformation of 8-oxoguanine to guanidinohydantoin and spiroiminodihydantoin by density functional theory.

  Journal of the American Chemical Society 20080416

• Compensatory and long-range changes in picosecond-nanosecond main-chain dynamics upon complex formation: 15N relaxation analysis of the free and bound states of the ubiquitin-like domain of human plexin-B1 and the small GTPase Rac1.

  Journal of molecular biology 20080411

• Evolution of class-specific peptides targeting a hot spot of the Galphas subunit.

  Journal of molecular biology 20080411

• Rats with high or low sociability are differently affected by chronic variable stress.

  Neuroscience 20080409

• Conformer distribution in (cis-1,4-DACH)bis(guanosine-5'-phosphate)platinum(II) adducts: a reliable model for DNA adducts of antitumoral cisplatin.

  Inorganic chemistry 20080407

• Comparative pharmacological profiles of morphine and oxycodone under a neuropathic pain-like state in mice: evidence for less sensitivity to morphine.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080401

• Guanosine possesses specific modulatory effects on NMDA receptor-mediated neurotransmission in intact mice.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20080401

• Exogenous nucleosides accelerate differentiation of rat intestinal epithelial cells.

  The British journal of nutrition 20080401

• Influence of positive allosteric modulators on GABA(B) receptor coupling in rat brain: a scintillation proximity assay characterisation of G protein subtypes.

  Journal of neurochemistry 20080401

• Rho kinase is involved in Ca2+ entry of rat penile small arteries.

  American journal of physiology. Heart and circulatory physiology 20080401

• Up-regulation of adenosine receptors in the frontal cortex in Alzheimer's disease.

  Brain pathology (Zurich, Switzerland) 20080401

• Highly pathogenic RNA viral infections: challenges for antiviral research.

  Antiviral research 20080401

• Purine alkaloids from the South China Sea gorgonian Subergorgia suberosa.

  Journal of natural products 20080401

• Fetal haemoglobin response to hydroxycarbamide treatment and sar1a promoter polymorphisms in sickle cell anaemia.

  British journal of haematology 20080401

• Sex-dependent effects of periadolescent exposure to the cannabinoid agonist CP-55,940 on morphine self-administration behaviour and the endogenous opioid system.

  Neuropharmacology 20080401

• MT1 melatonin receptor internalization underlies melatonin-induced morphologic changes in Chinese hamster ovary cells and these processes are dependent on Gi proteins, MEK 1/2 and microtubule modulation.

  Journal of pineal research 20080401

• The effect of sildenafil on ocular blood flow.

  The British journal of ophthalmology 20080401

• Screening of anti-platelet aggregation agents from Panax notoginseng using human platelet extraction and HPLC-DAD-ESI-MS/MS.

  Journal of separation science 20080401

• Cloning, purification, and polymerization of Capsicum annuum recombinant alpha and beta tubulin.

  Bioscience, biotechnology, and biochemistry 20080401

• Darwinian evolution on a chip.

  PLoS biology 20080401

• High-throughput SHAPE analysis reveals structures in HIV-1 genomic RNA strongly conserved across distinct biological states.

  PLoS biology 20080401

• Role of phosphodiesterase 5 in synaptic plasticity and memory.

  Neuropsychiatric disease and treatment 20080401

• Treating refractory leukemias in childhood, role of clofarabine.

  Therapeutics and clinical risk management 20080401

• Single-day treatment for orolabial and genital herpes: a brief review of pathogenesis and pharmacology.

  Therapeutics and clinical risk management 20080401

• Novel D-amino acid tetrapeptides produce potent antinociception by selectively acting at peripheral kappa-opioid receptors.

  European journal of pharmacology 20080331

• Differential regulation of serotonin-1A receptor-stimulated [35S]GTP gamma S binding in the dorsal raphe nucleus by citalopram and escitalopram.

  European journal of pharmacology 20080331

• Methadone: does it really have low efficacy at micro-opioid receptors?

  Neuroreport 20080326

• Preparation and purification of 5'-amino-5'-deoxyguanosine-5'-N-phosphoramidate and its initiation properties with T7 RNA polymerase.

  Organic & biomolecular chemistry 20080321

• High-performance liquid chromatography determination of 5-methyl-2'-deoxycytidine, 2'-deoxycytidine, and other deoxynucleosides and nucleosides in DNA digests.

  Analytical biochemistry 20080315

• Genetic variation and response to morphine in cancer patients: catechol-O-methyltransferase and multidrug resistance-1 gene polymorphisms are associated with central side effects.

  Cancer 20080315

• Novel trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines as mu opioid receptor antagonists with improved opioid receptor selectivity profiles.

  Bioorganic & medicinal chemistry letters 20080315

• Large and stable transmembrane pores from guanosine-bile acid conjugates.

  Journal of the American Chemical Society 20080312

• Synthesis of guanosine 5'-conjugates and their use as initiator molecules for transcription priming.

  Organic & biomolecular chemistry 20080307

• Electron transfer between guanosine radicals and amino acids in aqueous solution. II. Reduction of guanosine radicals by tryptophan.

  The journal of physical chemistry. B 20080306

• Structural changes of eIF4E upon binding to the mRNA 5' monomethylguanosine and trimethylguanosine Cap.

  Biochemistry 20080304

• Meeting report: cGMP matters.

  Science signaling 20080304

• Chronic morphine use does not induce peripheral tolerance in a rat model of inflammatory pain.

  The Journal of clinical investigation 20080303

• Impairment of muscarinic transmission in transgenic APPswe/PS1dE9 mice.

  Neurobiology of aging 20080301

• Alpha 2A-adrenoceptor-specific stimulation of [35S]GTP gamma S binding to membrane preparations of rat frontal cortex.

  Neurochemical research 20080301

• The use of circular dichroism spectroscopy for studying the chiral molecular self-assembly: an overview.

  Chirality 20080301

• Molecular characterization of vibrio cholerae DeltarelA DeltaspoT double mutants.

  Archives of microbiology 20080301

• Feedback control of ribosome function in Escherichia coli.

  Biochimie 20080301

• Roles of Rho guanosine 5'-triphosphatase A, Rho kinases, and extracellular signal regulated kinase (1/2) in prostaglandin E2-mediated migration of first-trimester human extravillous trophoblast.

  Endocrinology 20080301

• Morphine-induced analgesic tolerance, locomotor sensitization and physical dependence do not require modification of mu opioid receptor, cdk5 and adenylate cyclase activity.

  Neuropharmacology 20080301

• 2-Methoxymethyl-salvinorin B is a potent kappa opioid receptor agonist with longer lasting action in vivo than salvinorin A.

  The Journal of pharmacology and experimental therapeutics 20080301

• Characterization of the molecular fragment that is responsible for agonism of pergolide at serotonin 5-Hydroxytryptamine2B and 5-Hydroxytryptamine2A receptors.

  The Journal of pharmacology and experimental therapeutics 20080301

• Characterization of epoxyeicosatrienoic acid binding site in U937 membranes using a novel radiolabeled agonist, 20-125i-14,15-epoxyeicosa-8(Z)-enoic acid.

  The Journal of pharmacology and experimental therapeutics 20080301

• Low-fat diet and exercise preserve eNOS regulation and endothelial function in the penis of early atherosclerotic pigs: a molecular analysis.

  The journal of sexual medicine 20080301

• Quantification and comparison of toll-like receptor expression and responsiveness in primary and immortalized human female lower genital tract epithelia.

  American journal of reproductive immunology (New York, N.Y. : 1989) 20080301

• Neuroanatomical mapping of juvenile rat brain regions with prominent basal signal in [(35)S]GTPgammaS autoradiography.

  Journal of chemical neuroanatomy 20080301

• GTPgammaS incorporation in the rat brain: a study on mu-opioid receptors and CXCR4.

  Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20080301

• Enhanced NMR signal detection of imino protons in RNA molecules containing 3' dangling nucleotides.

  Journal of biomolecular NMR 20080301

• Role of redox signaling and poly (adenosine diphosphate-ribose) polymerase activation in vascular smooth muscle cell growth inhibition by nitric oxide and peroxynitrite.

  Journal of vascular surgery 20080301

• Streptomyces clavuligerus relA-null mutants overproduce clavulanic acid and cephamycin C: negative regulation of secondary metabolism by (p)ppGpp.

  Microbiology (Reading, England) 20080301

• Rho GTPase activation assays.

  Current protocols in cell biology 20080301

• Phosphorylation-independent regulation of the diguanylate cyclase WspR.

  PLoS biology 20080301

• Remyelination after chronic spinal cord injury is associated with proliferation of endogenous adult progenitor cells after systemic administration of guanosine.

  Purinergic signalling 20080301

• Effect of locked-nucleic acid on a biologically active g-quadruplex. A structure-activity relationship of the thrombin aptamer.

  International journal of molecular sciences 20080301

• Unique agonist-bound cannabinoid CB1 receptor conformations indicate agonist specificity in signaling.

  European journal of pharmacology 20080226

• Antipsychotics differ in their ability to internalise human dopamine D2S and human serotonin 5-HT1A receptors in HEK293 cells.

  European journal of pharmacology 20080226

• Impact of the oxidized guanine lesion spiroiminodihydantoin on the conformation and thermodynamic stability of a 15-mer DNA duplex.

  Biochemistry 20080226

• Importance of platinum(II)-assisted platinum(IV) substitution for the oxidation of guanosine derivatives by platinum(IV) complexes.

  Inorganic chemistry 20080218

• Cellular nucleic acid binding protein binds G-rich single-stranded nucleic acids and may function as a nucleic acid chaperone.

  Journal of cellular biochemistry 20080215

• GTP up-regulated persistent Na+ current and enhanced nociceptor excitability require NaV1.9.

  The Journal of physiology 20080215

• Studies on umami taste. Synthesis of new guanosine 5'-phosphate derivatives and their synergistic effect with monosodium glutamate.

  Journal of agricultural and food chemistry 20080213

• Distribution of nucleosides and nucleobases in edible fungi.

  Journal of agricultural and food chemistry 20080213

• Hepatic oxidative DNA damage is associated with increased risk for hepatocellular carcinoma in chronic hepatitis C.

  British journal of cancer 20080212

• The TbMTr1 spliced leader RNA cap 1 2'-O-ribose methyltransferase from Trypanosoma brucei acts with substrate specificity.

  The Journal of biological chemistry 20080208

• Specific recognition of Rac2 and Cdc42 by DOCK2 and DOCK9 guanine nucleotide exchange factors.

  The Journal of biological chemistry 20080208

• 3D reconstruction of mammalian septin filaments.

  Journal of molecular biology 20080208

• The thermodynamics of 3'-terminal pyrene and guanosine for the design of isoenergetic 2'-O-methyl-RNA-LNA chimeric oligonucleotide probes of RNA structure.

  Biochemistry 20080205

• Exploring specificity of glycosyltransferases: synthesis of new sugar nucleotide related molecules as putative donor substrates.

  Carbohydrate research 20080204

• Sub-plasmalemmal [Ca2+]i upstroke in myocytes of the guinea-pig small intestine evoked by muscarinic stimulation: IP3R-mediated Ca2+ release induced by voltage-gated Ca2+ entry.

  Cell calcium 20080201

• Role of ionization of the phosphate cosubstrate on phosphorolysis by purine nucleoside phosphorylase (PNP) of bacterial (E. coli) and mammalian (human) origin.

  European biophysics journal : EBJ 20080201

• Coupling of the guanosine glycosidic bond conformation and the ribonucleotide cleavage reaction: implications for barnase catalysis.

  Proteins 20080201

• Mechanism of guanosine-induced neuroprotection in rat hippocampal slices submitted to oxygen-glucose deprivation.

  Neurochemistry international 20080201

• Dose-related differences in the regional pattern of cannabinoid receptor adaptation and in vivo tolerance development to delta9-tetrahydrocannabinol.

  The Journal of pharmacology and experimental therapeutics 20080201

• Hydroxyurea nitrosylates and activates soluble guanylyl cyclase in human erythroid cells.

  Blood 20080201

• Memantine agonist action at dopamine D2High receptors.

  Synapse (New York, N.Y.) 20080201

• Dopamine partial agonist actions of the glutamate receptor agonists LY 354,740 and LY 379,268.

  Synapse (New York, N.Y.) 20080201

• Activities of mixed NOP and mu-opioid receptor ligands.

  British journal of pharmacology 20080201

• Synthesis and pharmacological characterization of a novel, highly potent, peptidomimetic delta-opioid radioantagonist, [3H]Tyr-Tic-(2S,3R)-beta-MePhe-Phe-OH.

  Neuropeptides 20080201

• Synthesis and anti-HIV activity of 2'-fluorine modified nucleoside phosphonates: analogs of GS-9148.

  Bioorganic & medicinal chemistry letters 20080201

• cGMP-binding prepares PKG for substrate binding by disclosing the C-terminal domain.

  Journal of molecular biology 20080201

• A-to-I editing sites are a genomically encoded G: implications for the evolutionary significance and identification of novel editing sites.

  RNA (New York, N.Y.) 20080201

• In situ evaluation of heavy metal-DNA interactions using an electrochemical DNA biosensor.

  Bioelectrochemistry (Amsterdam, Netherlands) 20080201

• Synthesis and anti-HIV activity of GS-9148 (2'-Fd4AP), a novel nucleoside phosphonate HIV reverse transcriptase inhibitor.

  Bioorganic & medicinal chemistry letters 20080201

• Melatonin receptors in brain areas and ocular tissues of the teleost Tinca tinca: characterization and effect of temperature.

  General and comparative endocrinology 20080201

• The bacterial stringent response, conserved in chloroplasts, controls plant fertilization.

  Plant & cell physiology 20080201

• pyr RNA binding to the Bacillus caldolyticus PyrR attenuation protein - characterization and regulation by uridine and guanosine nucleotides.

  The FEBS journal 20080201

• Formation of gutingimycin: analytical investigation of trioxacarcin A-mediated alkylation of dsDNA.

  Analytical and bioanalytical chemistry 20080201

• Determination of new types of DNA lesions in human sperm.

  Zygote (Cambridge, England) 20080201

• Clinical application of CpG-, non-CpG-, and antisense oligodeoxynucleotides as immunomodulators.

  Current opinion in molecular therapeutics 20080201

• Adenylyl cyclase-cyclicAMP signaling in mood disorders: role of the crucial phosphorylating enzyme protein kinase A.

  Neuropsychiatric disease and treatment 20080201

• Tunable thermoassociation of binary guanosine gels.

  The journal of physical chemistry. B 20080131

• Neuroprotective effects of guanosine on stroke models in vitro and in vivo.

  Neuroscience letters 20080131

• Pertussis toxin induces parallel loss of neuropeptide Y Y1 receptor dimers and Gi alpha subunit function in CHO cells.

  European journal of pharmacology 20080128

• Influence of soluble guanylate cyclase inhibition on inflammation and motility disturbances in DSS-induced colitis.

  European journal of pharmacology 20080128

• Structural requirements for the activation of Escherichia coli CTP synthase by the allosteric effector GTP are stringent, but requirements for inhibition are lax.

  The Journal of biological chemistry 20080125

• DNA-protein cross-links between guanine and lysine depend on the mechanism of oxidation for formation of C5 vs C8 guanosine adducts.

  Journal of the American Chemical Society 20080116

• Oxidative stress in neurodegeneration in dentatorubral-pallidoluysian atrophy.

  Journal of the neurological sciences 20080115

• A fast synthetic route to GDP-sugars modified at the nucleobase.

  Chemical communications (Cambridge, England) 20080114

• Profile of glutamate uptake and cellular viability in hippocampal slices exposed to oxygen and glucose deprivation: developmental aspects and protection by guanosine.

  Brain research 20080110

• Long-term potentiation selectively expressed by NMDA receptors at hippocampal mossy fiber synapses.

  Neuron 20080110

• Dopamine and corticotropin-releasing factor synergistically alter basolateral amygdala-to-medial prefrontal cortex synaptic transmission: functional switch after chronic cocaine administration.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080109

• Regulation of platelet dense granule secretion by the Ral GTPase-exocyst pathway.

  The Journal of biological chemistry 20080104

• Pyrene-modified guanosine as fluorescent probe for DNA modulated by charge transfer.

  Bioorganic & medicinal chemistry 20080101

• Quinolinic acid-induced seizures stimulate glutamate uptake into synaptic vesicles from rat brain: effects prevented by guanine-based purines.

  Neurochemical research 20080101

• Noladin ether, a putative endocannabinoid, inhibits mu-opioid receptor activation via CB2 cannabinoid receptors.

  Neurochemistry international 20080101

• Nitric oxide-mediated anxiolytic-like and antidepressant-like effects in animal models of anxiety and depression.

  Pharmacology, biochemistry, and behavior 20080101

• Manipulation of fatty acid amide hydrolase functional activity alters sensitivity and dependence to ethanol.

  Journal of neurochemistry 20080101

• Regulation of A(2A) adenosine receptor expression and functioning following permanent focal ischemia in rat brain.

  Journal of neurochemistry 20080101

• Highly stable giant supramolecular vesicles composed of 2D hydrogen-bonded sheet structures of guanosine derivatives.

  Angewandte Chemie (International ed. in English) 20080101

• Self-assembly of N2-modified guanosine derivatives: formation of discrete G-octamers.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• GTP-independent rapid and slow endocytosis at a central synapse.

  Nature neuroscience 20080101

• Identification and functional analysis of novel (p)ppGpp synthetase genes in Bacillus subtilis.

  Molecular microbiology 20080101

• RNAi for treating hepatitis B viral infection.

  Pharmaceutical research 20080101

• Synergistic actions of diacylglycerol and inositol 1,4,5 trisphosphate for Ca2+-dependent inactivation of TRPC7 channel.

  Acta pharmacologica Sinica 20080101

• Kinetic pathway of pyrophosphorolysis by a retrotransposon reverse transcriptase.

  PloS one 20080101

• Codon usage suggests that translational selection has a major impact on protein expression in trypanosomatids.

  BMC genomics 20080101

• Biochemical characterization of transporter associated with antigen processing (TAP)-like (ABCB9) expressed in insect cells.

  Biological & pharmaceutical bulletin 20080101

• Expression of membrane progesterone receptors on human T lymphocytes and Jurkat cells and activation of G-proteins by progesterone.

  The Journal of endocrinology 20080101

• Structure of the yeast tRNA m7G methylation complex.

  Structure (London, England : 1993) 20080101

• Visible light modulates the expression of cancer-retina antigens.

  Molecular cancer research : MCR 20080101

• Cyclic tetranuclear half-sandwich ruthenium(II) complexes with 4,7-phenanthroline and hydroxo bridges: crystal structure, solution behaviour and binding to nucleosides.

  Journal of inorganic biochemistry 20080101

• Substrate specificity and molecular modelling of the feline herpesvirus-1 thymidine kinase.

  Archives of virology 20080101

• Inhibition of hyaluronan export reduces collagen degradation in interleukin-1 treated cartilage.

  Arthritis research & therapy 20080101

• Estrogen and progesterone modulate [35S]GTPgammaS binding to nociceptin receptors.

  Neuroendocrinology 20080101

• Role of vasopressin in the treatment of anaphylactic shock in a child undergoing surgery for congenital heart disease: a case report.

  Journal of medical case reports 20080101

• The extracytoplasmic stress factor, sigmaE, is required to maintain cell envelope integrity in Escherichia coli.

  PloS one 20080101

• Visual field defect as a presenting sign for hemorrhagic stroke caused by sildenafil.

  Indian journal of ophthalmology 20080101

• Co-expression and promoter content analyses assign a role in biotic and abiotic stress responses to plant natriuretic peptides.

  BMC plant biology 20080101

• RNAi and RNAa--the yin and yang of RNAome.

  Bioinformation 20080101

• G-rich oligonucleotides alter cell cycle progression and induce apoptosis specifically in OE19 esophageal tumor cells.

  Oligonucleotides 20080101

• Cyclic GMP in the pig vitreous and retina after experimental retinal detachment.

  Molecular vision 20080101

• Radiation cataracts: mechanisms involved in their long delayed occurrence but then rapid progression.

  Molecular vision 20080101

• B12-retro-riboswitches: guanosyl-induced constitutional switching of B12 coenzymes.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• Expression of interferon-stimulated gene 20 in vascular endothelial cells.

  Microbiology and immunology 20080101

• Charge environments around phosphorylation sites in proteins.

  BMC structural biology 20080101

• Vesicular trafficking: molecular tools and targets.

  Methods in molecular biology (Clifton, N.J.) 20080101

• Identification and characterization of interacting partners of Rab GTPases by yeast two-hybrid analyses.

  Methods in molecular biology (Clifton, N.J.) 20080101

• Displacement of protein-bound aptamers with small molecules screened by fluorescence polarization.

  Nature protocols 20080101

• Evidence for the intense exchange of MazG in marine cyanophages by horizontal gene transfer.

  PloS one 20080101

• Ribavirin considerations in treatment optimization.

  Antiviral therapy 20080101

• New advances in anti-HSV chemotherapy.

  Current medicinal chemistry 20080101

• Excessive islet NO generation in type 2 diabetic GK rats coincides with abnormal hormone secretion and is counteracted by GLP-1.

  PloS one 20080101

• Dynamics of oxidative damage at early stages of estrogen-dependant carcinogenesis.

  Advances in experimental medicine and biology 20080101

• High-throughput synthesis of HepDirect prodrugs of nucleoside monophosphates.

  Journal of combinatorial chemistry 20080101

• Subcellular localization and RNA interference of an RNA methyltransferase gene from silkworm, Bombyx mori.

  Comparative and functional genomics 20080101

• Exogenous nitric oxide requires an endothelial glycocalyx to prevent postischemic coronary vascular leak in guinea pig hearts.

  Critical care (London, England) 20080101

• Adaptation and mal-adaptation to ambient hypoxia; Andean, Ethiopian and Himalayan patterns.

  PloS one 20080101

• Genome-based construction of the metabolic pathways of Orientia tsutsugamushi and comparative analysis within the Rickettsiales order.

  Comparative and functional genomics 20080101

• [The role of ribavirin in the treatment of chronic hepatitis C].

  Przeglad epidemiologiczny 20080101

• Identification of differentially expressed proteins in spontaneous thymic lymphomas from knockout mice with deletion of p53.

  Proteome science 20080101

• IRES-mediated translation of utrophin A is enhanced by glucocorticoid treatment in skeletal muscle cells.

  PloS one 20080101

• The neuropeptide Y (NPY) Y2 receptors are largely dimeric in the kidney, but monomeric in the forebrain.

  Journal of receptor and signal transduction research 20080101

• Low response to pegylated interferon plus ribavirin in HIV-infected patients with chronic hepatitis C treated with abacavir.

  Antiviral therapy 20080101

• Automated discovery and phylogenetic analysis of new toxin-antitoxin systems.

  BMC microbiology 20080101

• [Study on processing for Rhizoma Pinelliae Praeparatum by comprehensive evaluation of multiple mark].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080101

• Immortalization of human melanocytes does not alter the de novo properties of nitric oxide to induce cell detachment from extracellular matrix components via cGMP.

  In vitro cellular & developmental biology. Animal 20080101

• IMP dehydrogenase basal activity in MOLT-4 human leukaemia cells is altered by mycophenolic acid and 6-thioguanosine.

  Scandinavian journal of clinical and laboratory investigation 20080101

• Transcriptional activity and distribution of splicing machinery elements during Hyacinthus orientalis pollen tube growth.

  Protoplasma 20080101

• Global regulation of nucleotide biosynthetic genes by c-Myc.

  PloS one 20080101

• Comparison of human B cell activation by TLR7 and TLR9 agonists.

  BMC immunology 20080101

• Remodeling of the Streptococcus agalactiae transcriptome in response to growth temperature.

  PloS one 20080101

• Establishment of rat embryonic stem cells and making of chimera rats.

  PloS one 20080101

• Evolutionary patterns in the sequence and structure of transfer RNA: a window into early translation and the genetic code.

  PloS one 20080101

• DnaC inactivation in Escherichia coli K-12 induces the SOS response and expression of nucleotide biosynthesis genes.

  PloS one 20080101

• Inhibition of the magnesium-sensitive TRPM7-like channel in cardiac myocytes by nonhydrolysable GTP analogs: involvement of phosphoinositide metabolism.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

• Chronic cigarette smoke causes oxidative damage and apoptosis to retinal pigmented epithelial cells in mice.

  PloS one 20080101

• Computational identification of four spliceosomal snRNAs from the deep-branching eukaryote Giardia intestinalis.

  PloS one 20080101

• Focal Adhesion Kinase contributes to insulin-induced actin reorganization into a mesh harboring Glucose transporter-4 in insulin resistant skeletal muscle cells.

  BMC cell biology 20080101

• 2'-Methylseleno modified oligoribonucleotides synthesized for X-ray crystallography.

  Nucleic acids symposium series (2004) 20080101

• Synthesis and study of 9-deazaguanosine derivatives as potential inhibitors of RNA virus replication.

  Nucleic acids symposium series (2004) 20080101

• ppGpp analogues as antibacterial compounds.

  Nucleic acids symposium series (2004) 20080101

• Long-term platinum retention after treatment with cisplatin and oxaliplatin.

  BMC clinical pharmacology 20080101

• Impact of viral replication inhibition by entecavir on peripheral T lymphocyte subpopulations in chronic hepatitis B patients.

  BMC infectious diseases 20080101

• Photodynamic therapy and the development of metal-based photosensitisers.

  Metal-based drugs 20080101

• Pioglitazone retrieves hepatic antioxidant DNA repair in a mice model of high fat diet.

  BMC molecular biology 20080101

• The small GTPase RhoH is an atypical regulator of haematopoietic cells.

  Cell communication and signaling : CCS 20080101

• Bench-to-bedside review: adenosine receptors--promising targets in acute lung injury?

  Critical care (London, England) 20080101

• The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase.

  BMC structural biology 20080101

• RNomics and Modomics in the halophilic archaea Haloferax volcanii: identification of RNA modification genes.

  BMC genomics 20080101

• Distinct expression of synaptic NR2A and NR2B in the central nervous system and impaired morphine tolerance and physical dependence in mice deficient in postsynaptic density-93 protein.

  Molecular pain 20080101

• Ectopic expression of a truncated CD40L protein from synthetic post-transcriptionally capped RNA in dendritic cells induces high levels of IL-12 secretion.

  BMC molecular biology 20080101

• Blood oxidative stress markers in non-alcoholic steatohepatitis and how it correlates with diet.

  Scandinavian journal of gastroenterology 20080101

• Did RNA editing in plant organellar genomes originate under natural selection or through genetic drift?

  Biology direct 20080101

• Dimers of the neuropeptide Y (NPY) Y2 receptor show asymmetry in agonist affinity and association with G proteins.

  Journal of receptor and signal transduction research 20080101

• Enhanced A3 adenosine receptor selectivity of multivalent nucleoside-dendrimer conjugates.

  Journal of nanobiotechnology 20080101

• The prince and the pauper. A tale of anticancer targeted agents.

  Molecular cancer 20080101

• The role of herpes simplex virus-1 thymidine kinase alanine 168 in substrate specificity.

  The open biochemistry journal 20080101

• Oxidative stress as a common mediator for apoptosis induced-cardiac damage in diabetic rats.

  The open cardiovascular medicine journal 20080101

• Association between inflammatory mediators and response to inhaled nitric oxide in a model of endotoxin-induced lung injury.

  Critical care (London, England) 20080101

• Abnormal energy regulation in early life: childhood gene expression may predict subsequent chronic mountain sickness.

  BMC pediatrics 20080101

• Comparing methods of detection and quantitation of RNA editing of rat glycine receptor alpha3.

  International journal of biological sciences 20080101

• Redox mechanisms in hepatic chronic wound healing and fibrogenesis.

  Fibrogenesis & tissue repair 20080101

• Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate.

  Reproductive biology and endocrinology : RB&E 20080101

• Absolute quantification of the budding yeast transcriptome by means of competitive PCR between genomic and complementary DNAs.

  BMC genomics 20080101

• Properties and distribution of pure GA-sequences of mammalian genomes.

  PloS one 20080101

• An internal ribosome entry site element directs the synthesis of the 80 kDa isoforms of protein 4.1R.

  BMC biology 20080101

• Pleiotropic effects of a rel mutation on stress survival of Rhizobium etli CNPAF512.

  BMC microbiology 20080101

• Flexible modulation of agonist efficacy at the human A3 adenosine receptor by the imidazoquinoline allosteric enhancer LUF6000.

  BMC pharmacology 20080101

• Integrase and integration: biochemical activities of HIV-1 integrase.

  Retrovirology 20080101

• Isocyanates induces DNA damage, apoptosis, oxidative stress, and inflammation in cultured human lymphocytes.

  Journal of biochemical and molecular toxicology 20080101

• Light-induced translocation of cyclic-GMP phosphodiesterase on rod disc membranes in rat retina.

  Molecular vision 20080101

• Novel therapies for cyclic GMP control of vascular smooth muscle growth.

  American journal of therapeutics 20080101

• The effect of preservation solutions UW and EC on purine concentration in rat kidney.

  Annales Academiae Medicae Stetinensis 20080101

• Rickettsia phylogenomics: unwinding the intricacies of obligate intracellular life.

  PloS one 20080101

• Repeated administration of the dopaminergic agonist apomorphine: development of apomorphine aggressiveness and changes in the interaction between dopamine D(2) receptors and G-proteins.

  Pharmacological reports : PR 20080101

• The human vaginal bacterial biota and bacterial vaginosis.

  Interdisciplinary perspectives on infectious diseases 20080101

• Emergency treatment of a snake bite: Pearls from literature.

  Journal of emergencies, trauma, and shock 20080101

• cGMP in ozone and NO dependent responses.

  Plant signaling & behavior 20080101

• Advances in antisense oligonucleotide development for target identification, validation, and as novel therapeutics.

  Gene regulation and systems biology 20080101

• Management of erythema nodosum leprosum by mycophenolate mofetil.

  Indian journal of dermatology 20080101

• The imaging probe development center and the production of molecular imaging probes.

  Current chemical genomics 20080101

• Psychological factors in asthma.

  Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20080101

• Recurrent Respiratory Papillomatosis (RRP)-Juvenile Onset.

  Clinical medicine. Oncology 20080101

• Herpes simplex Virus Esophagitis in an Immunocompetent Patient with Ebstein-Barr Virus Infection.

  Case reports in gastroenterology 20080101

• Synthesis of 5'-amino-5'-deoxyguanosine-5'-N-phosphoramidate and its enzymatic incorporation at the 5'-termini of RNA molecules.

  Chemical communications (Cambridge, England) 20071221

• Specific interaction between EF-G and RRF and its implication for GTP-dependent ribosome splitting into subunits.

  Journal of molecular biology 20071214

• Calcium-activated (p)ppGpp synthetase in chloroplasts of land plants.

  The Journal of biological chemistry 20071207

• A short and efficient synthesis of the tRNA nucleosides PreQ0 and archaeosine.

  Organic & biomolecular chemistry 20071207

• Synthesis and DNA incorporation of an ethynyl-bridged cytosine C-nucleoside as guanosine surrogate.

  Organic letters 20071206

• Short-term effects of 3,4-methylen-dioxy-metamphetamine (MDMA) on 5-HT(1A) receptors in the rat hippocampus.

  Neurochemistry international 20071201

• The basal levels of 8-oxoG and other oxidative modifications in intact mitochondrial DNA are low even in repair-deficient (Ogg1(-/-)/Csb(-/-)) mice.

  Mutation research 20071201

• Narrow-band UVB induces more carcinogenic skin tumors than broad-band UVB through the formation of cyclobutane pyrimidine dimer.

  The Journal of investigative dermatology 20071201

• An 80-amino acid deletion in the third intracellular loop of a naturally occurring human histamine H3 isoform confers pharmacological differences and constitutive activity.

  The Journal of pharmacology and experimental therapeutics 20071201

• The orphan receptor GPR55 is a novel cannabinoid receptor.

  British journal of pharmacology 20071201

• Proposal of a guanine-based purinergic system in the mammalian central nervous system.

  Pharmacology & therapeutics 20071201

• Regulatory interaction of the Galpha protein with phospholipase A2 in the plasma membrane of Eschscholzia californica.

  The Plant journal : for cell and molecular biology 20071201

• Nonenzymatic glycation of guanosine 5'-triphosphate by glyceraldehyde: an in vitro study of AGE formation.

  Bioorganic chemistry 20071201

• CB1 knockout mice display impaired functionality of 5-HT1A and 5-HT2A/C receptors.

  Journal of neurochemistry 20071201

• Endothelium-targeted transgenic GTP-cyclohydrolase I overexpression inhibits neointima formation in mouse carotid artery.

  Clinical and experimental pharmacology & physiology 20071201

• Base excision repair processing of abasic site/single-strand break lesions within clustered damage sites associated with XRCC1 deficiency.

  Nucleic acids research 20071201

• C-terminal truncated cannabinoid receptor 1 coexpressed with G protein trimer in Sf9 cells exists in a precoupled state and shows constitutive activity.

  The FEBS journal 20071201

• Endogenous heptapeptide Met-enkephalin-Gly-Tyr binds differentially to duplicate delta opioid receptors from zebrafish.

  Peptides 20071201

• In vitro screening of psychoactive drugs by [(35)S]GTPgammaS binding in rat brain membranes.

  Biological & pharmaceutical bulletin 20071201

• Role of calmodulin and myosin light chain kinase in the activation of carbachol-activated cationic current in murine ileal myocytes.

  Canadian journal of physiology and pharmacology 20071201

• Changes of nitric oxide, carbon monoxide and oxidative stress in term infants at birth.

  Free radical research 20071201

• Medicinal applications of fullerenes.

  International journal of nanomedicine 20071201

• Role of nelarabine in the treatment of T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma.

  Therapeutics and clinical risk management 20071201

• Human 5-HT(4) and 5-HT(7) receptor splice variants: are they important?

  Current neuropharmacology 20071201

• Nucleic acid aptamers for targeting of shRNA-based cancer therapeutics.

  Biologics : targets & therapy 20071201

• Secretory protein mRNA finds another way out.

  PLoS biology 20071201

• Allosteric small molecules unveil a role of an extracellular E2/transmembrane helix 7 junction for G protein-coupled receptor activation.

  The Journal of biological chemistry 20071130

• A charge reversal differentiates (p)ppGpp synthesis by monofunctional and bifunctional Rel proteins.

  The Journal of biological chemistry 20071130

• Induction of megakaryocytic differentiation in chronic myelogenous leukemia cell K562 by 3-hydrogenkwadaphnin.

  Journal of biochemistry and molecular biology 20071130

• Tickling-induced 50-kHz ultrasonic vocalization is individually stable and predicts behaviour in tests of anxiety and depression in rats.

  Behavioural brain research 20071122

• Dysregulation of the endogenous cannabinoid system in adult rats prenatally treated with the cannabinoid agonist WIN 55,212-2.

  European journal of pharmacology 20071114

• [Attention-getting sexually transmitted diseases: Hepatitis B].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20071110

• A bifunctional bacterial protein links GDI displacement to Rab1 activation.

  Science (New York, N.Y.) 20071109

• Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38.

  Science (New York, N.Y.) 20071109

• Inosine-containing dsRNA binds a stress-granule-like complex and downregulates gene expression in trans.

  Molecular cell 20071109

• Time-resolved resonance Raman investigation of the 2-fluorenylnitrenium ion reactions with C8 guanosine derivatives.

  The journal of physical chemistry. B 20071108

• Linkage between substrate recognition and catalysis during cleavage of sarcin/ricin loop RNA by restrictocin.

  Biochemistry 20071106

• Design of an optimal allele-specific oligonucleotide probe for the efficient discrimination of a thermodynamically stable (G x T) mismatch.

  Analytica chimica acta 20071105

• Overexpression of a Zn2+-sensitive soluble exopolyphosphatase from Trypanosoma cruzi depletes polyphosphate and affects osmoregulation.

  The Journal of biological chemistry 20071102

• Selective guanosine binding and cytotoxicity of a benzimidazole derived dinickel complex.

  Journal of inorganic biochemistry 20071101

• PSNCBAM-1, a novel allosteric antagonist at cannabinoid CB1 receptors with hypophagic effects in rats.

  British journal of pharmacology 20071101

• Significance of cannabinoid CB1 receptors in improgan antinociception.

  The journal of pain : official journal of the American Pain Society 20071101

• Characterization of guanine and guanosine transport in primary cultured rat cortical astrocytes and neurons.

  Glia 20071101

• Cyclic GMP and protein kinase-G in myocardial ischaemia-reperfusion: opportunities and obstacles for survival signaling.

  British journal of pharmacology 20071101

• C-type natriuretic peptide enhances amylase release through NPR-C receptors in the exocrine pancreas.

  American journal of physiology. Gastrointestinal and liver physiology 20071101

• The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects.

  British journal of pharmacology 20071101

• Kinetics and mechanism of the substitution reactions of [PtCl(bpma)]+, [PtCl(gly-met-S,N,N)] and their aqua analogues with L-methionine, glutathione and 5'-GMP.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20071101

• A select set of opioid ligands induce up-regulation by promoting the maturation and stability of the rat kappa-opioid receptor in human embryonic kidney 293 cells.

  The Journal of pharmacology and experimental therapeutics 20071101

• Extracellular renal guanosine cyclic 3'5'-monophosphate modulates nitric oxide and pressure-induced natriuresis.

  Hypertension (Dallas, Tex. : 1979) 20071101

• Developmental changes in agonist-induced retrograde signaling at parallel fiber-Purkinje cell synapses: role of calcium-induced calcium release.

  Journal of neurophysiology 20071101

• Effects of receptor density on Nociceptin/OrphaninFQ peptide receptor desensitisation: studies using the ecdysone inducible expression system.

  Naunyn-Schmiedeberg's archives of pharmacology 20071101

• Protein S-guanylation by the biological signal 8-nitroguanosine 3',5'-cyclic monophosphate.

  Nature chemical biology 20071101

• Ammonia elimination from protonated nucleobases and related synthetic substrates.

  Journal of the American Society for Mass Spectrometry 20071101

• Examination of the mechanism and energetic contribution of leaving group activation in the purine-specific nucleoside hydrolase from Trypanosoma vivax.

  Biochimica et biophysica acta 20071101

• G protein activation by uncaging of GTP-gamma-S in the leech giant glial cell.

  The Journal of experimental biology 20071101

• Effects of azimilide on the muscarinic acetylcholine receptor-operated K+ current and experimental atrial fibrillation in guinea-pig hearts.

  Journal of pharmacological sciences 20071101

• Effects of ginseng total saponins on pacemaker currents of interstitial cells of Cajal from the small intestine of mice.

  Biological & pharmaceutical bulletin 20071101

• tRNASer acceptor stem: conformation and hydration of a microhelix in a crystal structure at 1.8 A resolution.

  Acta crystallographica. Section D, Biological crystallography 20071101

• PF1270A, B and C, novel histamine H3 receptor ligands produced by Penicillium waksmanii PF1270.

  The Journal of antibiotics 20071101

• Effect of hydrogen peroxide on VIP-induced relaxation of the cat lower esophageal sphincter.

  Archives of pharmacal research 20071101

• Activation of protein kinase B/Akt and endothelial nitric oxide synthase mediates agmatine-induced endothelium-dependent relaxation.

  European journal of pharmacology 20071031

• Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibition.

  Biochemistry 20071030

• Reactions of fac-[Re(CO)3(H2O)3]+ with nucleoside diphosphates and thiamine diphosphate in aqueous solution investigated by multinuclear NMR spectroscopy.

  Inorganic chemistry 20071029

• Changes to the HIV long terminal repeat and to HIV integrase differentially impact HIV integrase assembly, activity, and the binding of strand transfer inhibitors.

  The Journal of biological chemistry 20071026

• Factors affecting guanine nucleotide binding to rat AMPA receptors.

  Brain research 20071026

• Chronic morphine treatment up-regulates mu opioid receptor binding in cells lacking filamin A.

  Brain research 20071026

• Efficient syntheses of 5'-deoxy-5'-fluoroguanosine and -inosine.

  The Journal of organic chemistry 20071026

• Spiroiminodihydantoin as an oxo-atom transfer product of 8-oxo-2'-deoxyguanosine oxidation by chromium(V).

  Organic letters 20071025

• Crystal structure of the radical SAM enzyme catalyzing tricyclic modified base formation in tRNA.

  Journal of molecular biology 20071005

• Urinary analysis of 8-oxoguanine, 8-oxoguanosine, fapy-guanine and 8-oxo-2'-deoxyguanosine by high-performance liquid chromatography-electrospray tandem mass spectrometry as a measure of oxidative stress.

  Journal of chromatography. A 20071005

• Muscarinic activity modulated by C-type natriuretic peptide in gastric smooth muscles of guinea-pig stomach.

  Regulatory peptides 20071004

• Effect of early rearing conditions on alcohol drinking and 5-HT1A receptor function in C57BL/6J mice.

  The international journal of neuropsychopharmacology 20071001

• Electroconvulsive shock treatment differentially modulates cortical and subcortical endocannabinoid activity.

  Journal of neurochemistry 20071001

• Self-organization of guanosine 5'-monophosphate on mica.

  Colloids and surfaces. B, Biointerfaces 20071001

• Low dose combination of morphine and delta9-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors.

  European journal of pharmacology 20071001

• [N-allyl-Dmt1]-endomorphins are micro-opioid receptor antagonists lacking inverse agonist properties.

  The Journal of pharmacology and experimental therapeutics 20071001

• Rho guanosine 5'-triphosphatases differentially regulate insulin-like growth factor I (IGF-I) receptor-dependent and -independent actions of IGF-II on human trophoblast migration.

  Endocrinology 20071001

• CAT-2 amplifies the agonist-evoked force of airway smooth muscle by enhancing spermine-mediated phosphatidylinositol-(4)-phosphate-5-kinase-gamma activity.

  American journal of physiology. Lung cellular and molecular physiology 20071001

• Pharmacokinetics and pharmacodynamics of seven opioids in P-glycoprotein-competent mice: assessment of unbound brain EC50,u and correlation of in vitro, preclinical, and clinical data.

  The Journal of pharmacology and experimental therapeutics 20071001

• (-)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol hydrochloride (tapentadol HCl): a novel mu-opioid receptor agonist/norepinephrine reuptake inhibitor with broad-spectrum analgesic properties.

  The Journal of pharmacology and experimental therapeutics 20071001

• Action of Pasteurella multocida toxin on Galpha(q) is persistent and independent of interaction with G-protein-coupled receptors.

  Cellular signalling 20071001

• Optimizing nitric oxide production by time dependent L-arginine administration in isolated human corpus cavernosum.

  The Journal of urology 20071001

• Structure-activity relationship studies of carboxamido-biaryl ethers as opioid receptor antagonists (OpRAs). Part 1.

  Bioorganic & medicinal chemistry letters 20071001

• Synthesis and application of 2'-fluoro-substituted cap analogs.

  Bioorganic & medicinal chemistry letters 20071001

• Inverse agonist exposure enhances ligand binding and G protein activation of the human MT1 melatonin receptor, but leads to receptor down-regulation.

  Journal of pineal research 20071001

• Equine recurrent airway obstruction does not alter airway muscarinic acetylcholine receptor expression and subtype distribution.

  Journal of veterinary pharmacology and therapeutics 20071001

• TLR agonists induce the differentiation of human bone marrow CD34+ progenitors into CD11c+ CD80/86+ DC capable of inducing a Th1-type response.

  European journal of immunology 20071001

• Spiroiminodihydantoin nucleoside formation from 2'-deoxyguanosine oxidation by [(18)O-labeled] singlet molecular oxygen in aqueous solution.

  Journal of mass spectrometry : JMS 20071001

• Segregation of odor identity and intensity during odor discrimination in Drosophila mushroom body.

  PLoS biology 20071001

• Saving the ischemic penumbra: potential role for statins and phosphodiesterase inhibitors.

  Current vascular pharmacology 20071001

• Gene regulation by mechanotransduction in fibroblasts.

  Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20071001

• Gingival crevicular fluid levels of neopterin in healthy subjects and in patients with different periodontal diseases.

  Journal of periodontology 20071001

• Nebivolol in the treatment of chronic heart failure.

  Vascular health and risk management 20071001

• The involvement of nitric oxide in ultraviolet-B-inhibited pollen germination and tube growth of Paulownia tomentosa in vitro.

  Physiologia plantarum 20071001

• N-Glycosylation of the human kappa opioid receptor enhances its stability but slows its trafficking along the biosynthesis pathway.

  Biochemistry 20070925

• Yeast mitochondrial initiator tRNA is methylated at guanosine 37 by the Trm5-encoded tRNA (guanine-N1-)-methyltransferase.

  The Journal of biological chemistry 20070921

• Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5.

  Journal of molecular biology 20070921

• Pyrazolo[3,4-d]pyrimidine ribonucleosides related to 2-aminoadenosine and isoguanosine: synthesis, deamination and tautomerism.

  Organic & biomolecular chemistry 20070921

• Inhibition of Mycobacterium tuberculosis, Mycobacterium bovis, and Mycobacterium avium by novel dideoxy nucleosides.

  Journal of medicinal chemistry 20070920

• Gas-phase formation of radical cations of monomers and dimers of guanosine by collision-induced dissociation of Cu(II)-guanosine complexes.

  The journal of physical chemistry. B 20070920

• Allosteric effects of antagonists on signalling by the chemokine receptor CCR5.

  Biochemical pharmacology 20070915

• Fast simultaneous determination of 14 nucleosides and nucleobases in cultured Cordyceps using ultra-performance liquid chromatography.

  Talanta 20070915

• Live cell monitoring of mu-opioid receptor-mediated G-protein activation reveals strong biological activity of close morphine biosynthetic precursors.

  The Journal of biological chemistry 20070914

• Novel diastereomeric opioid tetrapeptides exhibit differing pharmacological activity profiles.

  Brain research bulletin 20070914

• Adenosine deaminase 1 and concentrative nucleoside transporters 2 and 3 regulate adenosine on the apical surface of human airway epithelia: implications for inflammatory lung diseases.

  Biochemistry 20070911

• Translocation of activated heterotrimeric G protein Galpha(o) to ganglioside-enriched detergent-resistant membrane rafts in developing cerebellum.

  The Journal of biological chemistry 20070907

• Crystallographic and mass spectrometric characterisation of eIF4E with N7-alkylated cap derivatives.

  Journal of molecular biology 20070907

• Cysteine redox sensor in PKGIa enables oxidant-induced activation.

  Science (New York, N.Y.) 20070907

• Regulation of serotonin-1A receptor function in inducible brain-derived neurotrophic factor knockout mice after administration of corticosterone.

  Biological psychiatry 20070901

• Role of matrix metalloproteinase and tissue inhibitor of MMP in methamphetamine-induced behavioral sensitization and reward: implications for dopamine receptor down-regulation and dopamine release.

  Journal of neurochemistry 20070901

• Synthesis and anti-HIV activity of (-)-beta-D-(2R,4R)-1,3-dioxolane-2,6-diamino purine (DAPD) (amdoxovir) and (-)-beta-D-(2R,4R)-1,3-dioxolane guanosine (DXG) prodrugs.

  Antiviral research 20070901

• Preprodynorphin mediates locomotion and D2 dopamine and mu-opioid receptor changes induced by chronic 'binge' cocaine administration.

  Journal of neurochemistry 20070901

• Localization of the mouse 5-hydroxytryptamine(1A) receptor in lipid microdomains depends on its palmitoylation and is involved in receptor-mediated signaling.

  Molecular pharmacology 20070901

• 2'-O-methyl-modified RNAs act as TLR7 antagonists.

  Molecular therapy : the journal of the American Society of Gene Therapy 20070901

• DNAzyme-mediated inhibition of Japanese encephalitis virus replication in mouse brain.

  Molecular therapy : the journal of the American Society of Gene Therapy 20070901

• Assessing biomarkers of oxidative stress: analysis of guanosine and oxidized guanosine nucleotide triphosphates by high performance liquid chromatography with electrochemical detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070901

• Functionalization of the 6,14-bridge of the orvinols. Part 3: preparation and pharmacological evaluation of 18- and 19-hydroxyl substituted orvinols.

  Bioorganic & medicinal chemistry letters 20070901

• Stimulating and inhibitory effects of the dopamine 'stabilizer' (-)-OSU6162 on dopamine D2 receptor function in vitro.

  Journal of neural transmission (Vienna, Austria : 1996) 20070901

• The rare earth, scandium, causes antibiotic overproduction in Streptomyces spp.

  FEMS microbiology letters 20070901

• Mg2+ binding and archaeosine modification stabilize the G15 C48 Levitt base pair in tRNAs.

  RNA (New York, N.Y.) 20070901

• Protective effect of endothelial nitric oxide synthase against induction of chemically-induced diabetes in mice.

  Nitric oxide : biology and chemistry 20070901

• Three gene products govern (p)ppGpp production by Streptococcus mutans.

  Molecular microbiology 20070901

• The effect of varying continuous propofol infusions on plasma cyclic guanosine 3',5'-monophosphate concentrations in anesthetized children.

  Anesthesia and analgesia 20070901

• Role of nitric oxide pathway in placental dysfunction following fetal bypass.

  The Annals of thoracic surgery 20070901

• Guanosine acts intracellularly to initiate apoptosis in NB4 cells: A role for nucleoside transport.

  Leukemia & lymphoma 20070901

• Ameliorating the developmental neurotoxicity of chlorpyrifos: a mechanisms-based approach in PC12 cells.

  Environmental health perspectives 20070901

• A cyclic-di-GMP receptor required for bacterial exopolysaccharide production.

  Molecular microbiology 20070901

• Effects of oseltamivir phosphate (Tamiflu) and its metabolite (GS4071) on monoamine neurotransmission in the rat brain.

  Biological & pharmaceutical bulletin 20070901

• Mitochondria are an essential mediator of nitric oxide/cyclic guanosine 3',5'-monophosphate blocking of glucose depletion induced cytotoxicity in human HepG2 cells.

  Molecular cancer research : MCR 20070901

• TLR3 and TLR7 are involved in expression of IL-23 subunits while TLR3 but not TLR7 is involved in expression of IFN-beta by Theiler's virus-infected RAW264.7 cells.

  Microbes and infection 20070901

• A comprehensive genetic characterization of bacterial motility.

  PLoS genetics 20070901

• [(3)H]Adenine is a suitable radioligand for the labeling of G protein-coupled adenine receptors but shows high affinity to bacterial contaminations in buffer solutions.

  Purinergic signalling 20070901

• MPP(+)-induced cytotoxicity in neuroblastoma cells: Antagonism and reversal by guanosine.

  Purinergic signalling 20070901

• Guanosine reduces apoptosis and inflammation associated with restoration of function in rats with acute spinal cord injury.

  Purinergic signalling 20070901

• A review of antisense therapeutic interventions for molecular biological targets in asthma.

  Biologics : targets & therapy 20070901

• Intrinsic electrophilic properties of nucleosides: photoelectron spectroscopy of their parent anions.

  The Journal of chemical physics 20070828

• The RACK1 ortholog Asc1 functions as a G-protein beta subunit coupled to glucose responsiveness in yeast.

  The Journal of biological chemistry 20070824

• Helix 8 Leu in the CB1 cannabinoid receptor contributes to selective signal transduction mechanisms.

  The Journal of biological chemistry 20070824

• Metabotropic glutamate 2/3 receptors in the ventral tegmental area and the nucleus accumbens shell are involved in behaviors relating to nicotine dependence.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20070822

• Unusual structural features of hydantoin lesions translate into efficient recognition by Escherichia coli Fpg.

  Biochemistry 20070821

• Proteasome-dependent degradation of guanosine 5'-triphosphate cyclohydrolase I causes tetrahydrobiopterin deficiency in diabetes mellitus.

  Circulation 20070821

• Transcriptional networking cap-tures the 7SK RNA 5'-gamma-methyltransferase.

  Molecular cell 20070817

• The brain cytoplasmic RNA BC1 regulates dopamine D2 receptor-mediated transmission in the striatum.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20070815

• The mid-IR spectra of 9-ethyl guanine, guanosine, and 2-deoxyguanosine.

  The journal of physical chemistry. A 20070809

• Exogenous nucleic acids and nucleotides are efficiently hydrolysed and taken up as nucleosides by intestinal explants from suckling piglets.

  The British journal of nutrition 20070801

• Structural analysis of Cu(II) ligation to the 5'-GMP nucleotide by pulse EPR spectroscopy.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070801

• Mechanisms responsible for the enhanced antinociceptive effects of micro-opioid receptor agonists in the rostral ventromedial medulla of male rats with persistent inflammatory pain.

  The Journal of pharmacology and experimental therapeutics 20070801

• Pharmacological characterization of Sch527123, a potent allosteric CXCR1/CXCR2 antagonist.

  The Journal of pharmacology and experimental therapeutics 20070801

• Structure-function studies of allosteric agonism at M2 muscarinic acetylcholine receptors.

  Molecular pharmacology 20070801

• Urinary 8-hydroxydeoxyguanosine is elevated in patients with nephrolithiasis.

  Urological research 20070801

• Genome-wide transcriptome profiling of region-specific vulnerability to oxidative stress in the hippocampus.

  Genomics 20070801

• TLR-TLR cross talk in human PBMC resulting in synergistic and antagonistic regulation of type-1 and 2 interferons, IL-12 and TNF-alpha.

  International immunopharmacology 20070801

• Region-dependent attenuation of mu opioid receptor-mediated G-protein activation in mouse CNS as a function of morphine tolerance.

  British journal of pharmacology 20070801

• Action of novel antipsychotics at human dopamine D3 receptors coupled to G protein and ERK1/2 activation.

  Neuropharmacology 20070801

• In vitro pharmacological characterisation of a novel cyclic nociceptin/orphanin FQ analogue c[Cys(7,10)]N/OFQ(1-13)NH (2).

  Naunyn-Schmiedeberg's archives of pharmacology 20070801

• Sch35966 is a potent, selective agonist at the peripheral cannabinoid receptor (CB2) in rodents and primates.

  British journal of pharmacology 20070801

• Ultrafast electronic relaxation in guanosine is promoted by hydrogen bonding with cytidine.

  Journal of the American Chemical Society 20070801

• Mechanisms underlying agonist efficacy.

  Biochemical Society transactions 20070801

• Evaluation of nonleukoreduced red blood cell transfusion units collected at delivery from the placenta.

  Transfusion 20070801

• Guanosine gel for sequence-dependent separation of polymorphic ssDNA.

  Electrophoresis 20070801

• Intrinsic fluorescence of B and Z forms of poly d(G-m5C).poly d(G-m5C), a synthetic double-stranded DNA: spectra and lifetimes by the maximum entropy method.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20070801

• Co-localization and functional cross-talk between A1 and P2Y1 purine receptors in rat hippocampus.

  The European journal of neuroscience 20070801

• Nitroimidazole action in Entamoeba histolytica: a central role for thioredoxin reductase.

  PLoS biology 20070801

• Age-associated oxidative macromolecular damages in rat brain regions: role of glutathione monoester.

  The journals of gerontology. Series A, Biological sciences and medical sciences 20070801

• 1Alpha,25-dihydroxyvitamin D3 modulation of adipocyte reactive oxygen species production.

  Obesity (Silver Spring, Md.) 20070801

• [Apoptosis induced by base mismatches].

  Fukuoka igaku zasshi = Hukuoka acta medica 20070801

• [Chemical study of nucleosides on Cordyceps militaris].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070801

• Qualitative and quantitative analyses of nucleosides and nucleobases in Ganoderma spp. by HPLC-DAD-MS.

  Journal of pharmaceutical and biomedical analysis 20070727

• Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419).

  Journal of medicinal chemistry 20070726

• Quantifying hydrogen-bonding strength: the measurement of 2hJNN couplings in self-assembled guanosines by solid-state 15N spin-echo MAS NMR.

  Physical chemistry chemical physics : PCCP 20070714

• Nucleoside transporter expression and activity is regulated during granulocytic differentiation of NB4 cells in response to all-trans-retinoic acid.

  Leukemia research 20070701

• Relaxation of the isolated human internal anal sphincter by sildenafil.

  The British journal of surgery 20070701

• Genome-wide expression profiling in Geobacter sulfurreducens: identification of Fur and RpoS transcription regulatory sites in a relGsu mutant.

  Functional & integrative genomics 20070701

• Oxidative stress reduces renal dopamine D1 receptor-Gq/11alpha G protein-phospholipase C signaling involving G protein-coupled receptor kinase 2.

  American journal of physiology. Renal physiology 20070701

• Three distinct muscarinic signalling pathways for cationic channel activation in mouse gut smooth muscle cells.

  The Journal of physiology 20070701

• Simvastatin suppresses self-renewal of mouse embryonic stem cells by inhibiting RhoA geranylgeranylation.

  Stem cells (Dayton, Ohio) 20070701

• Thyrotropin activates guanosine 5'-diphosphate/guanosine 5'-triphosphate exchange on the rate-limiting endocytic catalyst, Rab5a, in human thyrocytes in vivo and in vitro.

  The Journal of clinical endocrinology and metabolism 20070701

• Synthesis and biological activity of new melatonin dimeric derivatives.

  Bioorganic & medicinal chemistry 20070701

• Synthesis and biological activity of nociceptin/orphanin FQ analogues substituted in position 7 or 11 with Calpha,alpha-dialkylated amino acids.

  Bioorganic & medicinal chemistry 20070701

• Modulation of a delayed-rectifier K+ current by angiotensin II in rat sympathetic neurons.

  Journal of neurophysiology 20070701

• Role of the stage-regulated nucleoside transporter TbNT10 in differentiation and adenosine uptake in Trypanosoma brucei.

  Molecular and biochemical parasitology 20070701

• Guanine derivatives modulate extracellular matrix proteins organization and improve neuron-astrocyte co-culture.

  Journal of neuroscience research 20070701

• Pentylenetetrazol kindling alters adenine and guanine nucleotide catabolism in rat hippocampal slices and cerebrospinal fluid.

  Epilepsy research 20070701

• Regulation of T-type calcium channels by Rho-associated kinase.

  Nature neuroscience 20070701

• Structure of a human telomeric DNA sequence stabilized by 8-bromoguanosine substitutions, as determined by NMR in a K+ solution.

  The FEBS journal 20070701

• Polyphosphate kinase is involved in stress-induced mprAB-sigE-rel signalling in mycobacteria.

  Molecular microbiology 20070701

• Functional analysis of the residues C770 and G771 of E. coli 16S rRNA implicated in forming the intersubunit bridge B2c of the ribosome.

  Journal of microbiology and biotechnology 20070701

• New platinum(II) complexes containing both an O,O'-chelated acetylacetonate ligand and a sulfur ligand in the platinum coordination sphere induce apoptosis in HeLa cervical carcinoma cells.

  Biochemical pharmacology 20070630

• Macrophage biospecific extraction and high performance liquid chromatography for hypothesis of immunological active components in Cordyceps sinensis.

  Journal of pharmaceutical and biomedical analysis 20070628

• Electron transfer between guanosine radical and amino acids in aqueous solution. 1. Reduction of guanosine radical by tyrosine.

  The journal of physical chemistry. B 20070628

• Substrate specificity of Fpg (MutM) and hOGG1, two repair glycosylases.

  Journal of the American Chemical Society 20070627

• Transcriptomal profiling of the cellular transformation induced by Rho subfamily GTPases.

  Oncogene 20070621

• Scaffold hopping, synthesis and structure-activity relationships of 5,6-diaryl-pyrazine-2-amide derivatives: a novel series of CB1 receptor antagonists.

  Bioorganic & medicinal chemistry 20070615

• Genetic selection for a highly functional cysteine-less membrane protein using site saturation mutagenesis.

  Analytical biochemistry 20070615

• Selective interactions of a few acridinium derivatives with single strand DNA: study of photophysical and DNA binding interactions.

  The journal of physical chemistry. B 20070614

• Site-selective depurination by a periodate-dependent deoxyribozyme.

  Chemical communications (Cambridge, England) 20070614

• Metabotropic glutamate receptor/phospholipase C system in female rat heart.

  Brain research 20070611

• fac-[Re(CO)3(H2O)3]+ nucleoside monophosphate adducts investigated in aqueous solution by multinuclear NMR spectroscopy.

  Inorganic chemistry 20070611

• Characterization of Rab45/RASEF containing EF-hand domain and a coiled-coil motif as a self-associating GTPase.

  Biochemical and biophysical research communications 20070608

• Nuclear membrane disassembly and rupture.

  Journal of molecular biology 20070608

• Useful detection of CD147 (EMMPRIN) for pathological diagnosis of early hepatocellular carcinoma in needle biopsy samples.

  World journal of gastroenterology 20070607

• X-ray crystal structures reveal two activated states for RhoC.

  Biochemistry 20070605

• Gene transcription alterations associated with decrease of ethanol intake induced by naltrexone in the brain of Wistar rats.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070601

• The capacity to remove 8-oxoG is enhanced in newborn neural stem/progenitor cells and decreases in juvenile mice and upon cell differentiation.

  DNA repair 20070601

• G protein activation inhibits gating charge movement in rat sympathetic neurons.

  American journal of physiology. Cell physiology 20070601

• GSK189254, a novel H3 receptor antagonist that binds to histamine H3 receptors in Alzheimer's disease brain and improves cognitive performance in preclinical models.

  The Journal of pharmacology and experimental therapeutics 20070601

• Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol]: in vitro studies.

  The Journal of pharmacology and experimental therapeutics 20070601

• Effects of chronic opioid exposure on guinea pig mu opioid receptor in Chinese hamster ovary cells: comparison with human and rat receptor.

  Biochemical pharmacology 20070601

• Rapid modulation of micro-opioid receptor signaling in primary sensory neurons.

  The Journal of pharmacology and experimental therapeutics 20070601

• In vitro and in vivo pharmacological characterization of ethyl-4-[trans-4-[((2S)-2-hydroxy-3-[4-hydroxy-3[(methylsulfonyl)amino]-phenoxy]propyl) amino]cyclohexyl]benzoate hydrochloride (SAR150640), a new potent and selective human beta3-adrenoceptor agonist for the treatment of preterm labor.

  The Journal of pharmacology and experimental therapeutics 20070601

• Identification of a platyhelminth neuropeptide receptor.

  International journal for parasitology 20070601

• Mutation studies of Ser7.39 and Ser2.60 in the human CB1 cannabinoid receptor: evidence for a serine-induced bend in CB1 transmembrane helix 7.

  Molecular pharmacology 20070601

• Incorporation of low molecular weight molecules into alpha(2)-macroglobulin by nucleophilic exchange.

  Biochemical and biophysical research communications 20070601

• Cleavage of an RNA analog by Zn(II) macrocyclic catalysts appended with a methyl or an acridine group.

  Journal of inorganic biochemistry 20070601

• Optimization of CEC for simultaneous determination of eleven nucleosides and nucleobases in Cordyceps using central composite design.

  Electrophoresis 20070601

• Homologous desensitization of signalling by the alpha (alpha) isoform of the human thromboxane A2 receptor: a specific role for nitric oxide signalling.

  Biochimica et biophysica acta 20070601

• Therapeutic issues in HIV/HCV-coinfected patients.

  Journal of viral hepatitis 20070601

• 8-oxo-7,8-dihydroguanosine triphosphate(8-oxoGTP) down-regulates respiratory burst of neutrophils by antagonizing GTP toward Rac, a small GTP binding protein.

  Free radical research 20070601

• Adrenaline stimulates H2O2 generation in liver via NADPH oxidase.

  Free radical research 20070601

• Different Ca2+ signalling cascades manifested by mastoparan in the prothoracic glands of the tobacco hornworm, Manduca sexta, and the silkworm, Bombyx mori.

  Archives of insect biochemistry and physiology 20070601

• Genetic inactivation of RelA/p65 sensitizes adult mouse hepatocytes to TNF-induced apoptosis in vivo and in vitro.

  Gastroenterology 20070601

• A dispermic chimera with mixed field blood group B and mosaic 46,XY/47,XYY karyotype.

  Journal of Korean medical science 20070601

• [Comparative study on main economic characters of different populations of Pinellia ternata in China].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070601

• Status epilepticus causes a long-lasting redistribution of hippocampal cannabinoid type 1 receptor expression and function in the rat pilocarpine model of acquired epilepsy.

  Neuroscience 20070525

• Proteinase-activated receptors 1 and 2 in rat olfactory system: layer-specific regulation of multiple signaling pathways in the main olfactory bulb and induction of neurite retraction in olfactory sensory neurons.

  Neuroscience 20070525

• OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells.

  Nature 20070524

• Effects of local anesthetics on opioid inhibition of calcium current in rat dorsal root ganglion neurons.

  Neuroscience letters 20070518

• Supramolecular polymers based on the quadruplex formation of ditopic guanosine macromonomers in nonaqueous media.

  Langmuir : the ACS journal of surfaces and colloids 20070508

• Lesion specificity in the base excision repair enzyme hNeil1: modeling and dynamics studies.

  Biochemistry 20070508

• 9-(2-C-Cyano-2-deoxy-beta-D-arabino-pentofuranosyl)guanine, a potential antitumor agent against B-lymphoma infected with Kaposi's sarcoma-associated herpesvirus.

  Journal of medicinal chemistry 20070503

• Pharmacological properties of bivalent ligands containing butorphan linked to nalbuphine, naltrexone, and naloxone at mu, delta, and kappa opioid receptors.

  Journal of medicinal chemistry 20070503

• The mechanism of cyclic nucleotide hydrolysis in the phosphodiesterase catalytic site.

  The journal of physical chemistry. B 20070503

• 172G>T variant in the 5' untranslated region of DNA repair gene RAD51 reduces risk of squamous cell carcinoma of the head and neck and interacts with a P53 codon 72 variant.

  Carcinogenesis 20070501

• Crystal structure of mammalian alpha1,6-fucosyltransferase, FUT8.

  Glycobiology 20070501

• The impact of different chelating leaving groups on the substitution kinetics of mononuclear Pt(II)(1,2-trans-R,R-diaminocyclohexane)(X-Y) complexes.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070501

• Visualization of 2-arachidonoylglycerol accumulation and cannabinoid CB1 receptor activity in rat brain cryosections by functional autoradiography.

  Journal of neurochemistry 20070501

• Alterations in cytoskeletal protein expression by mycophenolic acid in human mesangial cells requires Rac inactivation.

  Biochemical pharmacology 20070501

• Different effects of opioid antagonists on mu-, delta-, and kappa-opioid receptors with and without agonist pretreatment.

  The Journal of pharmacology and experimental therapeutics 20070501

• Protean agonism at the dopamine D2 receptor: (S)-3-(3-hydroxyphenyl)-N-propylpiperidine is an agonist for activation of Go1 but an antagonist/inverse agonist for Gi1,Gi2, and Gi3.

  Molecular pharmacology 20070501

• Quantitative evaluation of human delta opioid receptor desensitization using the operational model of drug action.

  Molecular pharmacology 20070501

• Evidence for the role of G-proteins in flow stimulation of dinoflagellate bioluminescence.

  American journal of physiology. Regulatory, integrative and comparative physiology 20070501

• Firing properties of accessory olfactory bulb mitral/tufted cells in response to urine delivered to the vomeronasal organ of gray short-tailed opossums.

  Chemical senses 20070501

• Biochemical anti-opioid action of NPFF2 receptors in rat spinal cord.

  Neuroscience research 20070501

• The in vitro pharmacology of the peripherally restricted opioid receptor antagonists, alvimopan, ADL 08-0011 and methylnaltrexone.

  Naunyn-Schmiedeberg's archives of pharmacology 20070501

• Guanosine 3',5'-cyclic monophosphate (cGMP)/cGMP-dependent protein kinase induce interleukin-6 transcription in osteoblasts.

  Molecular endocrinology (Baltimore, Md.) 20070501

• Metabotropic P2Y receptors inhibit P2X3 receptor-channels via G protein-dependent facilitation of their desensitization.

  British journal of pharmacology 20070501

• Mechanisms of G protein activation via the D2 dopamine receptor: evidence for persistent receptor/G protein interaction after agonist stimulation.

  British journal of pharmacology 20070501

• Immunoreactivity and guanosine 3',5'-cyclic monophosphate activating actions of various molecular forms of human B-type natriuretic peptide.

  Hypertension (Dallas, Tex. : 1979) 20070501

• Biochemical and structural characterization of mammalian-like purine nucleoside phosphorylase from the Archaeon Pyrococcus furiosus.

  The FEBS journal 20070501

• The role of cargo proteins in GGA recruitment.

  Traffic (Copenhagen, Denmark) 20070501

• The P2Y2 nucleotide receptor requires interaction with alpha v integrins to access and activate G12.

  Journal of cell science 20070501

• Oral donepezil reduces hypersensitivity after nerve injury by a spinal muscarinic receptor mechanism.

  Anesthesiology 20070501

• An antisense RNA controls synthesis of an SOS-induced toxin evolved from an antitoxin.

  Molecular microbiology 20070501

• Analysis of Beta-Tubulin Gene Exon 4 Mutations in Advanced Stage III or IV Gastric Cancer.

  Journal of clinical biochemistry and nutrition 20070501

• Probing the role of a secondary structure element at the 5'- and 3'-splice sites in group I intron self-splicing: the tetrahymena L-16 ScaI ribozyme reveals a new role of the G.U pair in self-splicing.

  Biochemistry 20070424

• Identification of an in vivo inhibitor of Bacillus anthracis spore germination.

  The Journal of biological chemistry 20070420

• Role of kappa and delta opioid receptors in mediating morphine-induced antinociception in morphine-tolerant infant rats.

  Brain research 20070420

• Mutational analysis of the mitochondrial tRNALeu(UUR) gene in Tunisian patients with mitochondrial diseases.

  Biochemical and biophysical research communications 20070420

• D- and L-2',3'-didehydro-2',3'-dideoxy-3'-fluoro-carbocyclic nucleosides: synthesis, anti-HIV activity and mechanism of resistance.

  Journal of medicinal chemistry 20070419

• Nearest neighbor parameters for inosine x uridine pairs in RNA duplexes.

  Biochemistry 20070417

• DNA-probes for the highly sensitive identification of single nucleotide polymorphism using single-molecule spectroscopy.

  FEBS letters 20070417

• Structure-based design of benzylamino-acridine compounds as G-quadruplex DNA telomere targeting agents.

  Bioorganic & medicinal chemistry letters 20070415

• Electrocatalytic oxidation of guanine, guanosine, and guanosine monophosphate.

  Biophysical journal 20070415

• Synthesis and structure-activity relationships of N-substituted spiropiperidines as nociceptin receptor ligands.

  Bioorganic & medicinal chemistry letters 20070415

• Histamine H3 and dopamine D2 receptor-mediated [35S]GTPgamma[S] binding in rat striatum: evidence for additive effects but lack of interactions.

  Biochemical pharmacology 20070415

• Involvement of endogenous opioid peptides in the antinociception induced by the novel dermorphin tetrapeptide analog amidino-TAPA.

  European journal of pharmacology 20070410

• N-Desmethylclozapine, a major clozapine metabolite, acts as a selective and efficacious delta-opioid agonist at recombinant and native receptors.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070401

• Synthesis and hydrolysis of pppGpp in mycobacteria: a ligand mediated conformational switch in Rel.

  Biophysical chemistry 20070401

• Uncovering the pharmacology of the G protein-coupled receptor GPR40: high apparent constitutive activity in guanosine 5'-O-(3-[35S]thio)triphosphate binding studies reflects binding of an endogenous agonist.

  Molecular pharmacology 20070401

• 8-Oxoguanosine and uracil repair of nuclear and mitochondrial DNA in red and white skeletal muscle of exercise-trained old rats.

  Journal of applied physiology (Bethesda, Md. : 1985) 20070401

• Thienorphine: receptor binding and behavioral effects in rhesus monkeys.

  The Journal of pharmacology and experimental therapeutics 20070401

• G-ribo: a new structural motif in ribosomal RNA.

  RNA (New York, N.Y.) 20070401

• Evaluation of cellular dielectric spectroscopy, a whole-cell, label-free technology for drug discovery on Gi-coupled GPCRs.

  Journal of biomolecular screening 20070401

• Nitroxyl anion donor, Angeli's salt, does not develop tolerance in rat isolated aortae.

  Hypertension (Dallas, Tex. : 1979) 20070401

• CC12, a high-affinity ligand for [3H]cimetidine binding, is an improgan antagonist.

  Neuropharmacology 20070401

• Synthesis and absolute configuration of cis- and trans-opened cyclopenta[cd]pyrene 3,4-oxide N2-deoxyguanosine adducts: conversion to phosphoramidites for oligonucleotide synthesis.

  Chemical research in toxicology 20070401

• Natural and synthetic TLR7 ligands inhibit CpG-A- and CpG-C-oligodeoxynucleotide-induced IFN-alpha production.

  Journal of immunology (Baltimore, Md. : 1950) 20070401

• Regulation of GTP cyclohydrolase I expression by orphan receptor Nurr1 in cell culture and in vivo.

  Journal of neurochemistry 20070401

• Bidirectional regulation of mu-opioid and CB1-cannabinoid receptor in rats self-administering heroin or WIN 55,212-2.

  The European journal of neuroscience 20070401

• Significance of error-avoiding mechanisms for oxidative DNA damage in carcinogenesis.

  Cancer science 20070401

• Antioxidants to reduce sperm DNA fragmentation: an unexpected adverse effect.

  Reproductive biomedicine online 20070401

• How and when environmental agents and dietary factors affect the course of Alzheimer's disease: the 'LEARn' model (latent early-life associated regulation) may explain the triggering of AD.

  Current Alzheimer research 20070401

• Entecavir: a new nucleoside analogue for the treatment of chronic hepatitis B.

  Drugs of today (Barcelona, Spain : 1998) 20070401

• Approach for assessing total cellular DNA damage.

  BioTechniques 20070401

• Pharmacological classification of histamine H3 receptor agents across species is attributable to transmembrane 3 sequence differences.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20070401

• Dopamine D2 receptor partial agonists display differential or contrasting characteristics in membrane and cell-based assays of dopamine D2 receptor signaling.

  Progress in neuro-psychopharmacology & biological psychiatry 20070330

• Inhibition of G alpha i2 activation by G alpha i3 in CXCR3-mediated signaling.

  The Journal of biological chemistry 20070330

• Dynorphin peptides differentially regulate the human kappa opioid receptor.

  Life sciences 20070320

• Dimethyl sulfoxide: an antagonist in scintillation proximity assay [(35)S]-GTPgammaS binding to rat 5-HT(6) receptor cloned in HEK-293 cells?

  Journal of neuroscience methods 20070315

• Synthesis and in vitro binding studies of substituted piperidine naphthamides. Part I: Influence of the substitution on the basic nitrogen and the position of the amide on the affinity for D2L, D4.2, and 5-HT2A receptors.

  Bioorganic & medicinal chemistry letters 20070315

• High-affinity carbamate analogues of morphinan at opioid receptors.

  Bioorganic & medicinal chemistry letters 20070315

• G-rich proto-oncogenes are targeted for genomic instability in B-cell lymphomas.

  Cancer research 20070315

• Mapping pathways downstream of sphingosine 1-phosphate subtype 1 by differential chemical perturbation and proteomics.

  The Journal of biological chemistry 20070309

• Cordycepin (3'-deoxyadenosine) inhibits human platelet aggregation in a cyclic AMP- and cyclic GMP-dependent manner.

  European journal of pharmacology 20070308

• Adolescent cannabis exposure alters opiate intake and opioid limbic neuronal populations in adult rats.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070301

• Progressive multifocal leukoencephalopathy in purine nucleoside phosphorylase deficiency.

  Brain & development 20070301

• Lysophosphatidylcholine mediates melanocyte dendricity through PKCzeta activation.

  The Journal of investigative dermatology 20070301

• Regulation of meiotic maturation.

  Journal of animal science 20070301

• Phosphorylation of SIMPL modulates RelA-associated NF-kappaB-dependent transcription.

  American journal of physiology. Cell physiology 20070301

• Adenosine A1 and A2 receptor agonists reduce endotoxin-induced cellular energy depletion and oedema formation in the lung.

  European journal of anaesthesiology 20070301

• Production of GDP-L-fucose, L-fucose donor for fucosyloligosaccharide synthesis, in recombinant Escherichia coli.

  Applied microbiology and biotechnology 20070301

• Differential regional effects of methadone maintenance compared to heroin dependence on mu-opioid receptor desensitization in rat brain.

  Synapse (New York, N.Y.) 20070301

• A comparison of noninternalizing (herkinorin) and internalizing (DAMGO) mu-opioid agonists on cellular markers related to opioid tolerance and dependence.

  Synapse (New York, N.Y.) 20070301

• Inhibition of agonist-induced down-regulation of the delta-opioid receptor with a proteasome inhibitor attenuates opioid tolerance in human embryonic kidney 293 cells.

  The Journal of pharmacology and experimental therapeutics 20070301

• Native rat hippocampal 5-HT1A receptors show constitutive activity.

  Molecular pharmacology 20070301

• Parallel inactivation of Y2 receptor and G-proteins in CHO cells by pertussis toxin.

  Regulatory peptides 20070301

• Dopamine D1 receptor coupling to Gs/olf and Gq in rat striatum and cortex: a scintillation proximity assay (SPA)/antibody-capture characterization of benzazepine agonists.

  Neuropharmacology 20070301

• Mitogen-activated protein kinase upregulation reduces renal D1 receptor affinity and G-protein coupling in obese rats.

  Kidney international 20070301

• Is the repair of oxidative DNA base modifications inducible by a preceding DNA damage induction?

  DNA repair 20070301

• An unexpected new role of mutant Ras: perturbation of human embryonic development.

  Journal of molecular medicine (Berlin, Germany) 20070301

• Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro.

  British journal of pharmacology 20070301

• Sildenafil reduces L-NAME-induced severe hypertension and worsening of myocardial ischaemia-reperfusion damage in the rat.

  British journal of pharmacology 20070301

• The psychoactive plant cannabinoid, Delta9-tetrahydrocannabinol, is antagonized by Delta8- and Delta9-tetrahydrocannabivarin in mice in vivo.

  British journal of pharmacology 20070301

• The fluorouridine insensitive 1 (fur1) mutant is defective in equilibrative nucleoside transporter 3 (ENT3), and thus represents an important pyrimidine nucleoside uptake system in Arabidopsis thaliana.

  The Plant journal : for cell and molecular biology 20070301

• Interpretation of fluorescence decay kinetics in 3-methylbenzimidazolyl(5'-5')guanosine dinucleotides: exponential dependence on the number of phosphates in the polyphosphate bridge.

  European biophysics journal : EBJ 20070301

• Time-resolved resonance Raman study of the reaction of the 2-fluorenylnitrenium ion with 2-fluorenylazide.

  The journal of physical chemistry. A 20070301

• Type 1 cytokine/chemokine production by mouse NK cells following activation of their TLR/MyD88-mediated pathways.

  International immunology 20070301

• Alternative splicing controls G protein-dependent inhibition of N-type calcium channels in nociceptors.

  Nature neuroscience 20070301

• Natriuretic peptide responsive, cyclic guanosine monophosphate producing structures in the guinea pig bladder.

  The Journal of urology 20070301

• Slow conformational dynamics of the guanine nucleotide-binding protein Ras complexed with the GTP analogue GTPgammaS.

  The FEBS journal 20070301

• Characterization of relA and codY mutants of Listeria monocytogenes: identification of the CodY regulon and its role in virulence.

  Molecular microbiology 20070301

• Effects of guanosine on the pharmacokinetics of acriflavine in rats following the administration of a 1:1 mixture of acriflavine and guanosine, a potential antitumor agent.

  Archives of pharmacal research 20070301

• P1 receptors and cytokine secretion.

  Purinergic signalling 20070301

• Agonist-stimulated [35S]GTPγS binding.

  Current protocols in pharmacology 20070301

• Probing hydrogen bonding and ion-carbonyl interactions by solid-state 17O NMR spectroscopy: G-ribbon and G-quartet.

  Journal of the American Chemical Society 20070227

• Direct 23Na NMR observation of mixed cations residing inside a G-quadruplex channel.

  Chemical communications (Cambridge, England) 20070227

• Voltammetric determination of adenosine and guanosine using fullerene-C(60)-modified glassy carbon electrode.

  Talanta 20070227

• Characterization of cannabinoid-binding sites in zebrafish brain.

  Neuroscience letters 20070221

• Microglial cells and peritoneal macrophages release activin A upon stimulation with Toll-like receptor agonists.

  Neuroscience letters 20070221

• In vitro studies on the binding, antioxidant, and cytotoxic actions of punicalagin.

  Journal of agricultural and food chemistry 20070221

• Prenatal cannabis exposure increases heroin seeking with allostatic changes in limbic enkephalin systems in adulthood.

  Biological psychiatry 20070215

• Functional reduction in mu-opioidergic system in the spinal cord under a neuropathic pain-like state following chronic ethanol consumption in the rat.

  Neuroscience 20070209

• Towards elucidation of the mechanism of UV1C, a deoxyribozyme with photolyase activity.

  Journal of molecular biology 20070202

• Amphetamine-induced locomotion, behavioral sensitization to amphetamine, and striatal D2 receptor function in rats with high or low spontaneous exploratory activity: differences in the role of locus coeruleus.

  Brain research 20070202

• Metabolic syndrome and urinary cGMP excretion in general population.

  Atherosclerosis 20070201

• Effect of graded corticosterone treatment on aging-related markers of oxidative stress in rat liver mitochondria.

  Biogerontology 20070201

• One-step purification of bacterially expressed recombinant transducin alpha-subunit and isotopically labeled PDE6 gamma-subunit for NMR analysis.

  Protein expression and purification 20070201

• Functional differences between NPFF1 and NPFF2 receptor coupling: high intrinsic activities of RFamide-related peptides on stimulation of [35S]GTPgammaS binding.

  Neuropharmacology 20070201

• Pre-synaptic histamine H3 receptors regulate glutamate, but not GABA release in rat thalamus.

  Neuropharmacology 20070201

• Involvement of Na,K-pump in SEPYLRFamide-mediated reduction of cholinosensitivity in Helix neurons.

  Regulatory peptides 20070201

• Salvinorin A: allosteric interactions at the mu-opioid receptor.

  The Journal of pharmacology and experimental therapeutics 20070201

• Contribution of both Ca2+ entry and Ca2+ sensitization to the alpha1-adrenergic vasoconstriction of rat penile small arteries.

  American journal of physiology. Heart and circulatory physiology 20070201

• SAR studies of 3-arylpropionic acids as potent and selective agonists of sphingosine-1-phosphate receptor-1 (S1P1) with enhanced pharmacokinetic properties.

  Bioorganic & medicinal chemistry letters 20070201

• Identification and structure-activity relationships of 1-aryl-3-piperidin-4-yl-urea derivatives as CXCR3 receptor antagonists.

  Bioorganic & medicinal chemistry letters 20070201

• Effect of the 252A>G polymorphism of the lymphotoxin-alpha gene on inflammatory markers of response to cigarette smoking in Korean healthy men.

  Clinica chimica acta; international journal of clinical chemistry 20070201

• Segment-dependent expression of muscarinic acetylcholine receptors and G-protein coupling in the equine respiratory tract.

  Veterinary research communications 20070201

• Self-regulation of agonist activity at the Y receptors.

  Peptides 20070201

• Increased brain neuropeptide Y1 and Y2 receptor binding in NPY knock out mice does not result in increased receptor function.

  Peptides 20070201

• Oxypurine and purine nucleoside concentrations in renal vein of allograft are potential markers of energy status of renal tissue.

  Archives of medical research 20070201

• The role of the omega subunit of RNA polymerase in expression of the relA gene in Escherichia coli.

  FEMS microbiology letters 20070201

• Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria.

  Molecular microbiology 20070201

• G protein-coupled inwardly rectifying potassium channels in dorsal root ganglion neurons.

  Acta pharmacologica Sinica 20070201

• Structure of radicals from X-irradiated guanine derivatives: an experimental and computational study of sodium guanosine dihydrate single crystals.

  The journal of physical chemistry. B 20070201

• Use of 5'-[p-(fluorosulfonyl)benzoyl] guanosine as an affinity probe for the guanine nucleotide-binding site of transducin.

  The protein journal 20070201

• Duodenal reflux leads to down regulation of DNA mismatch repair pathway in an animal model of esophageal cancer.

  The Annals of thoracic surgery 20070201

• Regulation of human internal mammary and radial artery contraction by extracellular and intracellular calcium channels and cyclic adenosine 3', 5' monophosphate.

  The Annals of thoracic surgery 20070201

• Supramolecular architectures generated by self-assembly of guanosine derivatives.

  Chemical Society reviews 20070201

• Nitric oxide and its gatekeeper thrombospondin-1 in tumor angiogenesis.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20070201

• Disruption of noradrenergic transmission and the behavioural response to a novel environment in NK1R-/- mice.

  The European journal of neuroscience 20070201

• Differential stringent responses of Streptomyces coelicolor M600 to starvation of specific nutrients.

  Journal of microbiology and biotechnology 20070201

• Vesicoureteric reflux and tumor necrosis factor-alpha gene polymorphism.

  Journal of pediatric urology 20070201

• Photophysical characterization of a cytidine-guanosine tethered phthalocyanine-fullerene dyad.

  Chemical communications (Cambridge, England) 20070121

• Identification of dynorphin a from zebrafish: a comparative study with mammalian dynorphin A.

  Neuroscience 20070119

• Critical role of methionine-722 in the stimulation of human brain G-proteins and neurotoxicity induced by London familial Alzheimer's disease (FAD) mutated V717G-APP(714-723).

  Neuroscience 20070119

• Cooperation of DEF6 with activated Rac in regulating cell morphology.

  The Journal of biological chemistry 20070119

• The extracellular nucleotide UTP is a potent inducer of hematopoietic stem cell migration.

  Blood 20070115

• Identification of selective neuropeptide Y2 peptide agonists.

  Bioorganic & medicinal chemistry letters 20070115

• Guanosine inhibits CD40 receptor expression and function induced by cytokines and beta amyloid in mouse microglia cells.

  Journal of immunology (Baltimore, Md. : 1950) 20070115

• Kinetic conformational analysis of human 8-oxoguanine-DNA glycosylase.

  The Journal of biological chemistry 20070112

• Withdrawal from a single exposure to cocaine increases 5-HT2A receptor and G protein function.

  Neuroreport 20070108

• NMR structure of a human homologous methuselah gene receptor peptide.

  Biochemical and biophysical research communications 20070105

• Simultaneous determination of guanosine and guanosine-5'-triphosphate in biological sample using gold nanoparticles modified indium tin oxide electrode.

  Analytica chimica acta 20070102

• Genetic impairment of frontocortical endocannabinoid degradation and high alcohol preference.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070101

• Conformations of adducts formed between the genotoxic benzo[a]pyrene-7,8-dione and nucleosides studied by density functional theory.

  Biophysical chemistry 20070101

• BF2.649 [1-{3-[3-(4-Chlorophenyl)propoxy]propyl}piperidine, hydrochloride], a nonimidazole inverse agonist/antagonist at the human histamine H3 receptor: Preclinical pharmacology.

  The Journal of pharmacology and experimental therapeutics 20070101

• Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assay.

  Molecular pharmacology 20070101

• The phosphofructokinase-B (MJ0406) from Methanocaldococcus jannaschii represents a nucleoside kinase with a broad substrate specificity.

  Extremophiles : life under extreme conditions 20070101

• Mycophenolate acid inhibits endothelial NAD(P)H oxidase activity and superoxide formation by a Rac1-dependent mechanism.

  Hypertension (Dallas, Tex. : 1979) 20070101

• Effect of olive oils on biomarkers of oxidative DNA stress in Northern and Southern Europeans.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070101

• Nitric oxide regulates cell survival in purified cultures of avian retinal neurons: involvement of multiple transduction pathways.

  Journal of neurochemistry 20070101

• Gonadotropin-controlled mammal oocyte meiotic resumption.

  Frontiers in bioscience : a journal and virtual library 20070101

• Little or no ability of obestatin to interact with ghrelin or modify motility in the rat gastrointestinal tract.

  British journal of pharmacology 20070101

• Effects of serotonin on the intrinsic membrane properties of layer II medial entorhinal cortex neurons.

  Hippocampus 20070101

• UVA irradiation induces relocalisation of the DNA repair protein hOGG1 to nuclear speckles.

  Journal of cell science 20070101

• Collision-induced dissociation of cytidine and its derivatives.

  Journal of mass spectrometry : JMS 20070101

• JNK- and Rac1-dependent induction of immediate early gene pip92 suppresses neuronal differentiation.

  Journal of neurochemistry 20070101

• Homocysteine, reactive oxygen species and nitric oxide in type 2 diabetes mellitus.

  Thrombosis research 20070101

• Selective decrease in the DNA base excision repair pathway in squamous cell cancer of the esophagus.

  The Journal of thoracic and cardiovascular surgery 20070101

• Augmenting effect of serotonin on the voltage-dependent Ca2+ current and subsequently activated K+ current in Aplysia neurons.

  The Tohoku journal of experimental medicine 20070101

• Nitric oxide in physiologic concentrations targets the translational machinery to increase the proliferation of human breast cancer cells: involvement of mammalian target of rapamycin/eIF4E pathway.

  Cancer research 20070101

• Phylogenetic distribution of translational GTPases in bacteria.

  BMC genomics 20070101

• Nitric oxide regulates input specificity of long-term depression and context dependence of cerebellar learning.

  PLoS computational biology 20070101

• The supramolecular helical architecture of 8-oxoinosine and 8-oxoguanosine derivatives.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

• Self-assembly of an alkylated guanosine derivative into ordered supramolecular nanoribbons in solution and on solid surfaces.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

• GraphDNA: a Java program for graphical display of DNA composition analyses.

  BMC bioinformatics 20070101

• A conformationally restricted guanosine analog reveals the catalytic relevance of three structures of an RNA enzyme.

  Chemistry & biology 20070101

• Automated querying of genome databases.

  PLoS computational biology 20070101

• Exploitation of eukaryotic ubiquitin signaling pathways by effectors translocated by bacterial type III and type IV secretion systems.

  PLoS pathogens 20070101

• Mandatory chromosomal segment balance in aneuploid tumor cells.

  BMC cancer 20070101

• In vitro study of antiviral activity of mycophenolic acid on Brazilian orthobunyaviruses.

  Intervirology 20070101

• RhoA/Rho kinase-mediated Ca2+ sensitization in the contraction of human prostate.

  Neurourology and urodynamics 20070101

• Gentamicin decreases guanylyl cyclase activity in rat glomerulus.

  Kidney & blood pressure research 20070101

• Europium tetracycline as a luminescent probe for nucleoside phosphates and its application to the determination of kinase activity.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

• Effective inhibition of lytic development of bacteriophages lambda, P1 and T4 by starvation of their host, Escherichia coli.

  BMC biotechnology 20070101

• RNA-editing-mediated exon evolution.

  Genome biology 20070101

• A mathematical model for the adenylosuccinate synthetase reaction involved in purine biosynthesis.

  Theoretical biology & medical modelling 20070101

• Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases.

  BMC bioinformatics 20070101

• Developmental stage related patterns of codon usage and genomic GC content: searching for evolutionary fingerprints with models of stem cell differentiation.

  Genome biology 20070101

• Large-scale mapping of human protein-protein interactions by mass spectrometry.

  Molecular systems biology 20070101

• Interaction of 2'-deoxyguanosine triphosphate analogue inhibitors of HIV reverse transcriptase with human mitochondrial DNA polymerase gamma.

  Antiviral chemistry & chemotherapy 20070101

• Replicative homeostasis III: implications for antiviral therapy and mechanisms of response and non-response.

  Virology journal 20070101

• The biochemical analysis of methadone modulation on morphine-induced tolerance and dependence in the rat brain.

  Pharmacology 20070101

• Reactome: a knowledge base of biologic pathways and processes.

  Genome biology 20070101

• Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase.

  BMC structural biology 20070101

• Cyclic GMP modulates the expression of Gi protein and adenylyl cyclase signaling in vascular smooth muscle cells.

  Cell biochemistry and biophysics 20070101

• Melatonin the 'light of night' in human biology and adolescent idiopathic scoliosis.

  Scoliosis 20070101

• The transcriptome analysis of early morphogenesis in Paracoccidioides brasiliensis mycelium reveals novel and induced genes potentially associated to the dimorphic process.

  BMC microbiology 20070101

• Mechanisms underlying vasorelaxant action of astragaloside IV in isolated rat aortic rings.

  Clinical and experimental pharmacology & physiology 20070101

• 5-HT1A receptor agonist properties of antipsychotics determined by [35S]GTPgammaS binding in rat hippocampal membranes.

  Clinical and experimental pharmacology & physiology 20070101

• Oxypurine and nucleoside concentrations in renal veins during reperfusion are predictors of early graft function.

  Scandinavian journal of urology and nephrology 20070101

• Searching genomes for ribozymes and riboswitches.

  Genome biology 20070101

• Specific fluorescent probe for 8-oxoguanosine.

  Angewandte Chemie (International ed. in English) 20070101

• Rab4A GTPase catenin interactions are involved in cell junction dynamics in the testis.

  Journal of andrology 20070101

• Unexpected observations after mapping LongSAGE tags to the human genome.

  BMC bioinformatics 20070101

• Analysis of gene expression in cotton fiber initials.

  BMC plant biology 20070101

• The Arabidopsis thaliana brassinosteroid receptor (AtBRI1) contains a domain that functions as a guanylyl cyclase in vitro.

  PloS one 20070101

• Multitracer positron emission tomographic imaging of exogenous gene expression mediated by a universal herpes simplex virus 1 amplicon vector.

  Molecular imaging 20070101

• ERK1/2 inactivation and p38 MAPK-dependent caspase activation during guanosine 5'-triphosphate-mediated terminal erythroid differentiation of K562 cells.

  The international journal of biochemistry & cell biology 20070101

• Guanosine and inosine (riboxin) eliminate the long-lived protein radicals induced X-ray radiation.

  Doklady. Biochemistry and biophysics 20070101

• Control of pre-mRNA splicing by the general splicing factors PUF60 and U2AF(65).

  PloS one 20070101

• RNA editing and alternative splicing of the insect nAChR subunit alpha6 transcript: evolutionary conservation, divergence and regulation.

  BMC evolutionary biology 20070101

• Hypoxia modulates cholinergic but not opioid activation of G proteins in rat hippocampus.

  Hippocampus 20070101

• Modulatory effects of nitric oxide-active drugs on the anticonvulsant activity of lamotrigine in an experimental model of partial complex epilepsy in the rat.

  BMC neuroscience 20070101

• Traumatic injury of the spinal cord and nitric oxide.

  Progress in brain research 20070101

• Phosphodiesterase 5 inhibitors lower both portal and pulmonary pressure in portopulmonary hypertension: a case report.

  Journal of medical case reports 20070101

• Neuronal conduction of excitation without action potentials based on ceramide production.

  PloS one 20070101

• Nucleoside and nucleotide reverse transcriptase inhibitors in children.

  Clinical drug investigation 20070101

• Do motor control genes contribute to interindividual variability in decreased movement in patients with pain?

  Molecular pain 20070101

• Comparative genomic and bioinformatic approaches for the identification of new adenosine-to-inosine substrates.

  Methods in enzymology 20070101

• Evolutionary genomics of plant genes encoding N-terminal-TM-C2 domain proteins and the similar FAM62 genes and synaptotagmin genes of metazoans.

  BMC genomics 20070101

• New pleiotropic effects of eliminating a rare tRNA from Streptomyces coelicolor, revealed by combined proteomic and transcriptomic analysis of liquid cultures.

  BMC genomics 20070101

• The global role of ppGpp synthesis in morphological differentiation and antibiotic production in Streptomyces coelicolor A3(2).

  Genome biology 20070101

• Hitting bacteria at the heart of the central dogma: sequence-specific inhibition.

  Microbial cell factories 20070101

• Molecular adsorbents recirculating system treatment in acute-on-chronic hepatitis patients on the transplant waiting list improves model for end-stage liver disease scores.

  Transplantation proceedings 20070101

• Wrinkly-Spreader fitness in the two-dimensional agar plate microcosm: maladaptation, compensation and ecological success.

  PloS one 20070101

• Three-dimensional imaging of Drosophila melanogaster.

  PloS one 20070101

• The p53 tumor suppressor-like protein nvp63 mediates selective germ cell death in the sea anemone Nematostella vectensis.

  PloS one 20070101

• The cys-loop ligand-gated ion channel gene superfamily of the red flour beetle, Tribolium castaneum.

  BMC genomics 20070101

• Zinc-bound metallothioneins and immune plasticity: lessons from very old mice and humans.

  Immunity & ageing : I & A 20070101

• A genetic code alteration is a phenotype diversity generator in the human pathogen Candida albicans.

  PloS one 20070101

• [Perturbations of the vesicle cycle in reticulospinal synapses of axons in lamprey after presynaptic microinjections of GTPgammaS].

  Tsitologiia 20070101

• Transcriptional networks in plasmacytoid dendritic cells stimulated with synthetic TLR 7 agonists.

  BMC immunology 20070101

• A new function for the Bacillus PbuE purine base efflux pump: efflux of purine nucleosides.

  Research in microbiology 20070101

• Microglial cells in astroglial cultures: a cautionary note.

  Journal of neuroinflammation 20070101

• The possible role of the ubiquitin proteasome system in the development of atherosclerosis in diabetes.

  Cardiovascular diabetology 20070101

• Translation initiation region sequence preferences in Escherichia coli.

  BMC molecular biology 20070101

• Increased ROS generation in subsets of OGG1 knockout fibroblast cells.

  Mechanisms of ageing and development 20070101

• The chemistry and biology of RNA editing by adenosine deaminases.

  Nucleic acids symposium series (2004) 20070101

• Synthesis of a guanosine phosphoramidite derivative containing a photocleavable protecting group at the O6 position via regioselective protection of the 2'-hydroxy group with a TBDMS group.

  Nucleic acids symposium series (2004) 20070101

• Development of a specific fluorescent probe for 8-oxoguanosine.

  Nucleic acids symposium series (2004) 20070101

• Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling.

  BMC biochemistry 20070101

• Codon-triplet context unveils unique features of the Candida albicans protein coding genome.

  BMC genomics 20070101

• OrthoMaM: a database of orthologous genomic markers for placental mammal phylogenetics.

  BMC evolutionary biology 20070101

• New analogs of acyclovir substituted at the side chain.

  Nucleosides, nucleotides & nucleic acids 20070101

• Synthesis of enantiopure pseudo-L-vinylcyclopropyl nucleosides bearing quaternary carbon as potential anti-herpesvirus agent.

  Nucleosides, nucleotides & nucleic acids 20070101

• Synthesis and biophysical characterization of G-rich oligonucleotides conjugated with sugar-phosphate tails.

  Nucleosides, nucleotides & nucleic acids 20070101

• Synthesis and characterization of tetra-end linked oligonucleotides capable of forming monomolecular G-quadruplexes.

  Nucleosides, nucleotides & nucleic acids 20070101

• Assignment of the absolute configuration of P-chiral 5' mRNA cap analogues containing phosphorothioate moiety.

  Nucleosides, nucleotides & nucleic acids 20070101

• Synthesis of 3H and 13C labeled mRNA cap dinucleotides--useful tools for NMR, biochemical, and biological studies.

  Nucleosides, nucleotides & nucleic acids 20070101

• Mismatch discrimination of base-modified nucleic acids and their constituents: non-Watson-Crick base pairing induced by tautomerization.

  Nucleosides, nucleotides & nucleic acids 20070101

• Discovery of ANA975: an oral prodrug of the TLR-7 agonist isatoribine.

  Nucleosides, nucleotides & nucleic acids 20070101

• Selective fluorescence detection of 8-oxoguanosine with 8-oxoG-clamp.

  Nucleosides, nucleotides & nucleic acids 20070101

• Interactions of calf spleen purine nucleoside phosphorylase with formycin B and its aglycone - spectroscopic and kinetic studies.

  Nucleosides, nucleotides & nucleic acids 20070101

• Cannabinoid CB(2)-selective inverse agonist protects against antigen-induced bone loss.

  Immunopharmacology and immunotoxicology 20070101

• Disruption of the plasma membrane integrity by cholesterol depletion impairs effectiveness of TRH receptor-mediated signal transduction via G(q)/G(11)alpha proteins.

  Journal of receptor and signal transduction research 20070101

• A scenario on the stepwise evolution of the genetic code.

  Genomics, proteomics & bioinformatics 20070101

• Synthesis of Novel 3-Aryl-N-Methyl-1,2,5,6-Tetrahydropyridine Derivatives by Suzuki coupling: As Acetyl Cholinesterase Inhibitors.

  The open medicinal chemistry journal 20070101

• DNA methylation in circulating tumour DNA as a biomarker for cancer.

  Biomarker insights 20070101

• Gene expression profiling in familial adenomatous polyposis adenomas and desmoid disease.

  Hereditary cancer in clinical practice 20070101

• Effect of ribavirin alone or combined with silymarin on carbon tetrachloride induced hepatic damage in rats.

  Drug target insights 20070101

• Disruption of RhoGDI and RhoA regulation by a Rac1 specificity switch mutant.

  The Journal of biological chemistry 20061229

• Active site labeling of G8 in the hairpin ribozyme: implications for structure and mechanism.

  Journal of the American Chemical Society 20061227

• A facile two-step synthesis of 8-arylated guanosine mono- and triphosphates (8-aryl GXPs).

  Organic & biomolecular chemistry 20061221

• In vitro characterization of SLV308 (7-[4-methyl-1-piperazinyl]-2(3H)-benzoxazolone, monohydrochloride): a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist.

  Synapse (New York, N.Y.) 20061215

• Aplindore (DAB-452), a high affinity selective dopamine D2 receptor partial agonist.

  European journal of pharmacology 20061215

• Cell-based indicator to visualize picomolar dynamics of nitric oxide release from living cells.

  Analytical chemistry 20061215

• Adrenal hyperplasia and adenomas are associated with inhibition of phosphodiesterase 11A in carriers of PDE11A sequence variants that are frequent in the population.

  Cancer research 20061215

• High-throughput screening for functional adenosine to inosine RNA editing systems.

  ACS chemical biology 20061215

• Elucidation of the bioactive conformation of the N-substituted trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine class of mu-opioid receptor antagonists.

  Journal of medicinal chemistry 20061214

• Synthesis and pharmacological evaluation of novel octahydro-1H-pyrido[1,2-a]pyrazine as mu-opioid receptor antagonists.

  Journal of medicinal chemistry 20061214

• Design and synthesis of N-(3,3-diphenylpropenyl)alkanamides as a novel class of high-affinity MT2-selective melatonin receptor ligands.

  Journal of medicinal chemistry 20061214

• Asymmetric conformational changes in a GPCR dimer controlled by G-proteins.

  The EMBO journal 20061213

• Kinetics and mechanism of the oxidation of guanosine derivatives by Pt(IV) complexes.

  Inorganic chemistry 20061211

• Molecular basis of differences among statins and a comparison with antioxidant vitamins.

  The American journal of cardiology 20061204

• A case of late-onset Segawa syndrome (autosomal dominant dopa-responsive dystonia) with a novel mutation of the GTP-cyclohydrase I (GCH1) gene.

  Clinical neurology and neurosurgery 20061201

• Clinical evidence for lead-induced inhibition of nitric oxide formation.

  Archives of toxicology 20061201

• Profiles of purine biosynthesis, salvage and degradation in disks of potato (Solanum tuberosum L.) tubers.

  Planta 20061201

• Characterisation of the novel restriction endonuclease SuiI from Sulfolobus islandicus.

  Extremophiles : life under extreme conditions 20061201

• Impaired cerebrovascular reactivity after cortical spreading depression in rats: Restoration by nitric oxide or cGMP.

  Experimental neurology 20061201

• Mechanisms underlying type I mGluR-induced activation of lobster gastric mill neurons.

  Journal of neurophysiology 20061201

• Point mutations in the transmembrane region of GABAB2 facilitate activation by the positive modulator N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) in the absence of the GABAB1 subunit.

  Molecular pharmacology 20061201

• Pain sensitivity is altered in animals after subchronic ketamine treatment.

  Psychopharmacology 20061201

• Evidence that corticotropin-releasing factor receptor type 1 couples to Gs- and Gi-proteins through different conformations of its J-domain.

  British journal of pharmacology 20061201

• Activation of nematode G protein GOA-1 by the human muscarinic acetylcholine receptor M2 subtype. Functional coupling of G-protein-coupled receptor and G protein originated from evolutionarily distant animals.

  The FEBS journal 20061201

• Dynamic roles for G4 DNA in the biology of eukaryotic cells.

  Nature structural & molecular biology 20061201

• Mycophenolic acid induces islet apoptosis by regulating mitogen-activated protein kinase activation.

  Transplantation proceedings 20061201

• Erythrocyte G protein as a novel target for malarial chemotherapy.

  PLoS medicine 20061201

• Fz2 and cdc42 mediate melanization and actin polymerization but are dispensable for Plasmodium killing in the mosquito midgut.

  PLoS pathogens 20061201

• Regulation of cGMP synthesis in cultured podocytes by vasoactive hormones.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20061201

• Determination of the impurity profile of adenosine by means of ion-pair reversed-phase chromatography.

  Pharmeuropa scientific notes 20061201

• Nanomedicines in the treatment of patients with hepatitis C co-infected with HIV--focus on pegylated interferon-alpha.

  International journal of nanomedicine 20061201

• Sildenafil in the treatment of erectile dysfunction: an overview of the clinical evidence.

  Clinical interventions in aging 20061201

• Azacytidine (Vidaza(R)) in the treatment of myelodysplastic syndromes.

  Therapeutics and clinical risk management 20061201

• Numerical characterization of DNA sequences based on the k-step Markov chain transition probability.

  Journal of computational chemistry 20061130

• 3-Hydrogenkwadaphnin induces monocytic differentiation and enhances retinoic acid-mediated granulocytic differentiation in NB4 cell line.

  Journal of biochemistry and molecular biology 20061130

• Cation exchange in lipophilic G-quadruplexes: not all ion binding sites are equal.

  Journal of the American Chemical Society 20061129

• Mutational analysis of Encephalitozoon cuniculi mRNA cap (guanine-N7) methyltransferase, structure of the enzyme bound to sinefungin, and evidence that cap methyltransferase is the target of sinefungin's antifungal activity.

  The Journal of biological chemistry 20061124

• Investigation of guanosine-quartet assemblies by vibrational and electronic circular dichroism spectroscopy, a novel approach for studying supramolecular entities.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20061124

• The rewards of nicotine: regulation by tissue plasminogen activator-plasmin system through protease activated receptor-1.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20061122

• BRAG1, a Sec7 domain-containing protein, is a component of the postsynaptic density of excitatory synapses.

  Brain research 20061120

• Identification of Escherichia coli m2G methyltransferases: II. The ygjO gene encodes a methyltransferase specific for G1835 of the 23 S rRNA.

  Journal of molecular biology 20061117

• Medium-chain fatty acids as ligands for orphan G protein-coupled receptor GPR84.

  The Journal of biological chemistry 20061110

• Broad-spectrum effects of 4-aminopyridine to modulate amyloid beta1-42-induced cell signaling and functional responses in human microglia.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20061108

• Characterization and quantification of eight water-soluble constituents in tubers of Pinellia ternata and in tea granules from the Chinese multiherb remedy Xiaochaihu-tang.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061107

• Brain G protein-dependent signaling pathways in Down syndrome and Alzheimer's disease.

  Amino acids 20061101

• Effect of chronic ethanol exposure and its withdrawal on the endocannabinoid system.

  Neurochemistry international 20061101

• Functional expression of the GABAB receptor in human airway smooth muscle.

  American journal of physiology. Lung cellular and molecular physiology 20061101

• Methamphetamine-induced behavioral sensitization in mice: alterations in mu-opioid receptor.

  Journal of biomedical science 20061101

• Mechanism-based pharmacokinetic-pharmacodynamic modeling of the respiratory-depressant effect of buprenorphine and fentanyl in rats.

  The Journal of pharmacology and experimental therapeutics 20061101

• Probing the existence of G protein-coupled receptor dimers by positive and negative ligand-dependent cooperative binding.

  Molecular pharmacology 20061101

• Unaltered neuropeptide Y (NPY)-stimulated [35S]GTPgammaS binding suggests a net increase in NPY signalling after repeated electroconvulsive seizures in mice.

  Journal of neuroscience research 20061101

• Differential involvement of the endocannabinoid system in short- and long-term expression of incentive learning supported by nicotine in rats.

  Psychopharmacology 20061101

• Cooperation of phosphoinositides and BAR domain proteins in endosomal tubulation.

  Traffic (Copenhagen, Denmark) 20061101

• Store-operated Ca2+ influx in airway smooth muscle: Interactions between volatile anesthetic and cyclic nucleotide effects.

  Anesthesiology 20061101

• Natural resistance to HIV infection: The Vif-APOBEC interaction.

  Comptes rendus biologies 20061101

• Acyl carrier protein/SpoT interaction, the switch linking SpoT-dependent stress response to fatty acid metabolism.

  Molecular microbiology 20061101

• Adenosine-to-inosine RNA editing: perspectives and predictions.

  Mini reviews in medicinal chemistry 20061101

• Mycophenolic acid inhibits hepatitis C virus replication and acts in synergy with cyclosporin A and interferon-alpha.

  Gastroenterology 20061101

• Chlorine dioxide oxidation of guanosine 5'-monophosphate.

  Chemical research in toxicology 20061101

• Molecular mechanisms involved in anti-inflammatory effects of proton pump inhibitors.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20061101

• In vitro and in vivo studies of ribavirin action on Brazilian Orthobunyavirus.

  The American journal of tropical medicine and hygiene 20061101

• Imipramine inhibits A-type delayed rectifier and ATP-sensitive K+ currents independent of G-protein and protein kinase C in murine proximal colonic myocytes.

  Archives of pharmacal research 20061101

• First joint italian-german purine club meeting 'progress in purinergic receptor pharmacology and function'.

  Purinergic signalling 20061101

• Roles of P2 receptors in glial cells: focus on astrocytes.

  Purinergic signalling 20061101

• Signal transduction events induced by extracellular guanosine 5' triphosphate in excitable cells.

  Purinergic signalling 20061101

• Guanosine effect on cholesterol efflux and apolipoprotein E expression in astrocytes.

  Purinergic signalling 20061101

• Non-adenine based purines accelerate wound healing.

  Purinergic signalling 20061101

• Recent advances in structure and function of cytosolic IMP-GMP specific 5'-nucleotidase II (cN-II).

  Purinergic signalling 20061101

• Interaction of neurochondrin with the melanin-concentrating hormone receptor 1 interferes with G protein-coupled signal transduction but not agonist-mediated internalization.

  The Journal of biological chemistry 20061027

• Acid-base and metal-ion-binding properties of xanthosine 5'-monophosphate (XMP) in aqueous solution: complex stabilities, isomeric equilibria, and extent of macrochelation.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20061025

• Tautomerism in the guanyl radical.

  Journal of the American Chemical Society 20061025

• Chronic activation of spinal adenosine A1 receptors results in hypersensitivity.

  Neuroreport 20061023

• Characterization of the reactivity determinants of a novel hairpin substrate of yeast RNase III.

  Journal of molecular biology 20061020

• Structure-activity relationship of quinoline derivatives as potent and selective alpha(2C)-adrenoceptor antagonists.

  Journal of medicinal chemistry 20061019

• Base and phosphate electron detachment energies of deoxyribonucleotide anions.

  Journal of the American Chemical Society 20061018

• Modulation of dopamine D1 receptor signaling by adenosine A1 receptors in Sf9 cells requires expression of Gi proteins.

  Neuroscience letters 20061009

• On the physical nature of mesophases of guanosine gels.

  Physical chemistry chemical physics : PCCP 20061007

• Design, synthesis, and biological evaluation of new 1,8-naphthyridin-4(1H)-on-3-carboxamide and quinolin-4(1H)-on-3-carboxamide derivatives as CB2 selective agonists.

  Journal of medicinal chemistry 20061005

• Structural determinants of opioid activity in derivatives of 14-aminomorphinones: effects of changes to the chain linking of the C14-amino group to the aryl ring.

  Journal of medicinal chemistry 20061005

• Evolution of new function in the GTP cyclohydrolase II proteins of Streptomyces coelicolor.

  Biochemistry 20061003

• Mechanism of inhibition of TREK-2 (K2P10.1) by the Gq-coupled M3 muscarinic receptor.

  American journal of physiology. Cell physiology 20061001

• Synthesis and pharmacological studies of new hybrid derivatives of fentanyl active at the mu-opioid receptor and I2-imidazoline binding sites.

  Bioorganic & medicinal chemistry 20061001

• Separation of binding affinity and intrinsic activity of the potent mu-opioid 14-methoxymetopon.

  The Journal of pharmacology and experimental therapeutics 20061001

• Y(4) receptors mediate the inhibitory responses of pancreatic polypeptide in human and mouse colon mucosa.

  The Journal of pharmacology and experimental therapeutics 20061001

• Differential effects of 5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxyl]-5-pyridyl]carbamoyl]-6-trifluoromethylindone (SB 243213) on 5-hydroxytryptamine(2C) receptor-mediated responses.

  The Journal of pharmacology and experimental therapeutics 20061001

• Assays for enhanced activity of low efficacy partial agonists at the D(2) dopamine receptor.

  British journal of pharmacology 20061001

• Characterization of reactions of antimoniate and meglumine antimoniate with a guanine ribonucleoside at different pH.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20061001

• Relationship between systemic nitric oxide metabolites and cyclic GMP in healthy male volunteers.

  Acta physiologica (Oxford, England) 20061001

• In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands.

  British journal of pharmacology 20061001

• Predicting essential components of signal transduction networks: a dynamic model of guard cell abscisic acid signaling.

  PLoS biology 20061001

• Antinociception by spinal and systemic oxycodone: why does the route make a difference? In vitro and in vivo studies in rats.

  Anesthesiology 20061001

• Antiviral treatment of hepatitis C.

  Expert opinion on pharmacotherapy 20061001

• Nuclear magnetic resonance studies of the 4R and 4S diastereomers of spiroiminodihydantoin 2'-deoxyribonucleosides: absolute configuration and conformational features.

  Chemical research in toxicology 20061001

• Mechanism of PNA transport to the nuclear compartment.

  Annals of the New York Academy of Sciences 20061001

• Identification and characterization of a second, inducible promoter of relA in Escherichia coli.

  Genes & genetic systems 20061001

• [Studies on chemical constituents in flower of Abelmoschus manihot].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061001

• A kinetic, modeling and mechanistic re-analysis of thymidine phosphorylase and some related enzymes.

  Journal of enzyme inhibition and medicinal chemistry 20061001

• CpG-induced IFNgamma expands TLR4-specific IL-18 responses in vivo.

  Cellular immunology 20061001

• Dopamine D2 receptor-mediated G protein activation assessed by agonist-stimulated [35S]guanosine 5'-O-(gamma-thiotriphosphate) binding in rat striatal membranes.

  Progress in neuro-psychopharmacology & biological psychiatry 20060930

• GTP induces S-phase cell-cycle arrest and inhibits DNA synthesis in K562 cells but not in normal human peripheral lymphocytes.

  Journal of biochemistry and molecular biology 20060930

• Cortical feedback to the thalamus is selectively enhanced by nitric oxide.

  Neuroscience 20060929

• Aripiprazole and its human metabolite are partial agonists at the human dopamine D2 receptor, but the rodent metabolite displays antagonist properties.

  European journal of pharmacology 20060928

• Progestins' effects on sexual behaviour of female rats and hamsters involving D1 and GABA(A) receptors in the ventral tegmental area may be G-protein-dependent.

  Behavioural brain research 20060925

• Coupling of ORL1 (NOP) receptor to G proteins is decreased in the nucleus accumbens of anxious relative to non-anxious mice.

  Brain research 20060919

• Cross-linking transglutaminases with G protein-coupled receptor signaling.

  Science's STKE : signal transduction knowledge environment 20060919

• Different receptors mediate the electrophysiological and growth cone responses of an identified neuron to applied dopamine.

  Neuroscience 20060915

• Mycophenolic acid inhibits mesangial cell activation through p38 MAPK inhibition.

  Life sciences 20060913

• Analysis of brain adrenergic receptors in dopamine-beta-hydroxylase knockout mice.

  Brain research 20060913

• A cannabinoid receptor 1 mutation proximal to the DRY motif results in constitutive activity and reveals intramolecular interactions involved in receptor activation.

  Brain research 20060907

• Formation of a miscible supramolecular polymer blend through self-assembly mediated by a quadruply hydrogen-bonded heterocomplex.

  Journal of the American Chemical Society 20060906

• Targeted guanine oxidation by a dinuclear copper(II) complex at single stranded/double stranded DNA junctions.

  Inorganic chemistry 20060904

• Chemistry of HIV-1 virucidal Pt complexes having neglected bidentate sp2 N-donor carrier ligands with linked triazine and pyridine rings. synthesis, NMR spectral features, structure, and reaction with guanosine.

  Inorganic chemistry 20060904

• The very C-terminus of PRK1/PKN is essential for its activation by RhoA and downstream signaling.

  Cellular signalling 20060901

• Crystal structures of GMP kinase in complex with ganciclovir monophosphate and Ap5G.

  Biochimie 20060901

• Pharmacological characterization of novel water-soluble cannabinoids.

  The Journal of pharmacology and experimental therapeutics 20060901

• Prolonged recovery rate of CB1 receptor adaptation after cessation of long-term cannabinoid administration.

  Molecular pharmacology 20060901

• Regional differences in the coupling of 5-hydroxytryptamine-1A receptors to G proteins in the rat brain.

  Molecular pharmacology 20060901

• Antinociceptive activity of chemical congeners of improgan: optimization of side chain length leads to the discovery of a new, potent, non-opioid analgesic.

  Neuropharmacology 20060901

• A guanylate kinase/HSV-1 thymidine kinase fusion protein enhances prodrug-mediated cell killing.

  Gene therapy 20060901

• SB-699551-A (3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4'-{[(2-phenylethyl)amino]methyl}-4-biphenylyl)methyl]propanamide dihydrochloride), a novel 5-ht5A receptor-selective antagonist, enhances 5-HT neuronal function: Evidence for an autoreceptor role for the 5-ht5A receptor in guinea pig brain.

  Neuropharmacology 20060901

• DRD2/DARPP-32 expression correlates with lymph node metastasis and tumor progression in patients with esophageal squamous cell carcinoma.

  World journal of surgery 20060901

• CYK-4/GAP provides a localized cue to initiate anteroposterior polarity upon fertilization.

  Science (New York, N.Y.) 20060901

• AIB1 promotes DNA replication by JNK repression and AKT activation during cellular stress.

  Journal of biochemistry 20060901

• Muscarinic receptor-activated cationic channels in murine ileal myocytes.

  British journal of pharmacology 20060901

• A distributed chemosensory circuit for oxygen preference in C. elegans.

  PLoS biology 20060901

• Structural basis for the interaction of CCR5 with a small molecule, functionally selective CCR5 agonist.

  Journal of immunology (Baltimore, Md. : 1950) 20060901

• Guanosine 5'-triphosphate induces differentiation-dependent apoptosis in human leukemia U937 and KG1 cells.

  Acta pharmacologica Sinica 20060901

• Structure of Methanocaldococcus jannaschii nucleoside kinase: an archaeal member of the ribokinase family.

  Acta crystallographica. Section D, Biological crystallography 20060901

• Human trabecular meshwork cells express functional serotonin-2A (5HT2A) receptors: role in IOP reduction.

  Investigative ophthalmology & visual science 20060901

• Designing siRNA that distinguish between genes that differ by a single nucleotide.

  PLoS genetics 20060901

• Metabolic loading of guanosine induces chondrocyte apoptosis via the Fas pathway.

  Experimental & molecular medicine 20060831

• Changes in CB1 receptors in motor-related brain structures of chronic relapsing experimental allergic encephalomyelitis mice.

  Brain research 20060830

• Serotonin 1a receptor and associated G-protein activation in schizophrenia and bipolar disorder.

  Psychiatry research 20060830

• Chronic morphine administration results in tolerance to delta opioid receptor-mediated antinociception.

  Neuroscience 20060825

• Alterations of the expression and activity of midbrain nitric oxide synthase and soluble guanylyl cyclase in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice.

  Neuroscience 20060825

• Synthetic functional pi-stack architecture in lipid bilayers.

  Organic & biomolecular chemistry 20060821

• Syntheses, pi-stacking interactions and base-pairings of uracil pyridinium salts and uracilyl betaines with nucleobases.

  Organic & biomolecular chemistry 20060821

• Comparison of ribonucleic acid homopolymer ionization energies and charge injection barriers.

  The journal of physical chemistry. B 20060817

• G-quartet formation from an N2-modified guanosine derivative.

  Organic letters 20060817

• Evaluation of two novel tag-based labelling technologies for site-specific modification of proteins.

  International journal of biological macromolecules 20060815

• Unique presynaptic and postsynaptic roles of Group II metabotropic glutamate receptors in the modulation of thalamic network activity.

  Neuroscience 20060811

• Guanine oxidation: one- and two-electron reactions.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20060807

• Base triplet nonisomorphism strongly influences DNA triplex conformation: effect of nonisomorphic G* GC and A* AT triplets and bending of DNA triplexes.

  Biopolymers 20060805

• Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35.

  The Journal of biological chemistry 20060804

• Solventless protocol for efficient bis-N-boc protection of adenosine, cytidine, and guanosine derivatives.

  The Journal of organic chemistry 20060804

• Synthesis, oxidation behavior, crystallization and structure of 2'-methylseleno guanosine containing RNAs.

  Journal of the American Chemical Society 20060802

• Functional interactions between the alpha1b-adrenoceptor and Galpha11 are compromised by de-palmitoylation of the G protein but not of the receptor.

  Cellular signalling 20060801

• Linking the nutritional status of Streptococcus pyogenes to alteration of transcriptional gene expression: the action of CodY and RelA.

  International journal of medical microbiology : IJMM 20060801

• Correlation between a gene polymorphism of tumor necrosis factor-alpha (G/A) and end-stage renal disease: a pilot study from north India.

  Clinica chimica acta; international journal of clinical chemistry 20060801

• Serum antiguanosine antibodies as a marker for SLE disease activity and pathogen potential.

  Clinica chimica acta; international journal of clinical chemistry 20060801

• Synthesis, cannabinoid receptor activity, and enzymatic stability of reversed amide derivatives of arachidonoyl ethanolamide.

  Bioorganic & medicinal chemistry 20060801

• Differences in kinetics of xanomeline binding and selectivity of activation of G proteins at M(1) and M(2) muscarinic acetylcholine receptors.

  Molecular pharmacology 20060801

• Mu-delta opioid receptor functional interaction: Insight using receptor-G protein fusions.

  The Journal of pharmacology and experimental therapeutics 20060801

• The phosphoenolpyruvate carboxykinase of Mycobacterium tuberculosis induces strong cell-mediated immune responses in mice.

  Molecular and cellular biochemistry 20060801

• In-source CID of guanosine: gas phase ion-molecule reactions.

  Journal of the American Society for Mass Spectrometry 20060801

• Differentiation of 2'-O- and 3'-O-methylated ribonucleosides by tandem mass spectrometry.

  Journal of the American Society for Mass Spectrometry 20060801

• Dietary antioxidants and beneficial effect on oxidatively damaged DNA.

  Free radical biology & medicine 20060801

• Assembly and protection of the radical enzyme, methylmalonyl-CoA mutase, by its chaperone.

  Biochemistry 20060801

• The mitochondrial DNA A3243A>G mutation must be an infrequent cause of Asperger syndrome.

  The Journal of pediatrics 20060801

• Retinal vein occlusion associated with antithrombin deficiency secondary to a novel G9840C missense mutation.

  Archives of ophthalmology (Chicago, Ill. : 1960) 20060801

• [McCune-Albright syndrome: a difficult and complicated case study].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20060801

• Masked oral prodrugs of toll-like receptor 7 agonists: a new approach for the treatment of infectious disease.

  Current opinion in investigational drugs (London, England : 2000) 20060801

• From field to health: a simple way to increase the nutraceutical content of grape as shown by NO-dependent vascular relaxation.

  Journal of agricultural and food chemistry 20060726

• Genetic damage in cultured human keratinocytes stressed by long-term exposure to areca nut extracts.

  Mutation research 20060725

• Methylation and repeats in silent and nonsense mutations of p53.

  Mutation research 20060725

• Activation of the purine salvage pathway in mononuclear cells of cardiac recipients treated with mycophenolate mofetil.

  Transplantation 20060715

• MTH1, an oxidized purine nucleoside triphosphatase, prevents the cytotoxicity and neurotoxicity of oxidized purine nucleotides.

  DNA repair 20060713

• The high binding affinity of human ribosomal protein S3 to 7,8-dihydro-8-oxoguanine is abrogated by a single amino acid change.

  DNA repair 20060713

• NMR structure of an intracellular loop peptide derived from prostaglandin EP3alpha receptor.

  Biochemical and biophysical research communications 20060707

• Reversible interconversion between a supramolecular polymer and a discrete octameric species from a guanosine derivative by dynamic cation binding and release.

  Organic letters 20060706

• Chemical carcinogens in non-enzymatic cytosine deamination: 3-isocyanatoacrylonitrile.

  Journal of molecular modeling 20060701

• Levels of G-protein alpha q/11 subunits and of phospholipase C-beta(1-4), -gamma, and -delta1 isoforms in postmortem human brain caudate and cortical membranes: potential functional implications.

  Neurochemistry international 20060701

• Structural studies and mechanism of Saccharomyces cerevisiae dolichyl-phosphate-mannose synthase: insights into the initial step of synthesis of dolichyl-phosphate-linked oligosaccharide chains in membranes of endoplasmic reticulum.

  Glycobiology 20060701

• High accumulation of platinum-DNA adducts in strial marginal cells of the cochlea is an early event in cisplatin but not carboplatin ototoxicity.

  Molecular pharmacology 20060701

• Thienorphine is a potent long-acting partial opioid agonist: a comparative study with buprenorphine.

  The Journal of pharmacology and experimental therapeutics 20060701

• Sphingosine and its analog, the immunosuppressant 2-amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol, interact with the CB1 cannabinoid receptor.

  Molecular pharmacology 20060701

• Contribution of multidrug resistance protein MRP5 in control of cyclic guanosine 5'-monophosphate intracellular signaling in anterior pituitary cells.

  Endocrinology 20060701

• Transmembrane signaling through phospholipase C-beta in the developing human prefrontal cortex.

  Journal of neuroscience research 20060701

• In vitro and in vivo characterization of F-97013-GD, a partial 5-HT1A agonist with antipsychotic- and antiparkinsonian-like properties.

  Neuropharmacology 20060701

• A highly selective kappa-opioid receptor agonist with low addictive potential and dependence liability.

  Bioorganic & medicinal chemistry letters 20060701

• Pregnancy and estradiol modulate myometrial G-protein pathways in the guinea pig.

  American journal of obstetrics and gynecology 20060701

• In vitro biochemical evidence that the psychotomimetics phencyclidine, ketamine and dizocilpine (MK-801) are inactive at cloned human and rat dopamine D2 receptors.

  European journal of pharmacology 20060701

• Inhibition of dengue virus replication by mycophenolic acid and ribavirin.

  The Journal of general virology 20060701

• Modulating responsiveness of human TLR7 and 8 to small molecule ligands with T-rich phosphorothiate oligodeoxynucleotides.

  European journal of immunology 20060701

• Mass spectrometric identification and characterization of antimony complexes with ribose-containing biomolecules and an RNA oligomer.

  Analytical and bioanalytical chemistry 20060701

• The role of the RhoA/Rho-kinase signaling pathway in renal vascular reactivity in endothelial nitric oxide synthase null mice.

  Journal of hypertension 20060701

• Guanosine promotes the up-regulation of inward rectifier potassium current mediated by Kir4.1 in cultured rat cortical astrocytes.

  Journal of neurochemistry 20060701

• Calcium-stimulated guanosine--inosine nucleosidase from yellow lupin (Lupinus luteus).

  Phytochemistry 20060701

• Different nucleobase orientations in two cyclic 2',3'-phosphates of purine ribonucleosides: Et(3)NH(2',3'-cAMP) and Et(3)NH(2',3'-cGMP)xH(2)O.

  Acta crystallographica. Section C, Crystal structure communications 20060701

• Single-molecule dynamics reveals cooperative binding-folding in protein recognition.

  PLoS computational biology 20060701

• Assignment of absolute configurations of the enantiomeric spiroiminodihydantoin nucleobases by experimental and computational optical rotatory dispersion methods.

  Chemical research in toxicology 20060701

• Peptides derived from HIV-1, HIV-2, Ebola virus, SARS coronavirus and coronavirus 229E exhibit high affinity binding to the formyl peptide receptor.

  Biochimica et biophysica acta 20060701

• Analysis of internal motions of RNase T1 complexed with a productive substrate involving 15N NMR relaxation measurements.

  Journal of biochemistry 20060701

• Muscarinic receptor function, density and G-protein coupling in the overactive diabetic rat bladder.

  Autonomic & autacoid pharmacology 20060701

• Inhibition of the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway in hematologic malignancies.

  Current treatment options in oncology 20060701

• Enhanced expression of Gialpha protein and adenylyl cyclase signaling in aortas from 1 kidney 1 clip hypertensive rats.

  Canadian journal of physiology and pharmacology 20060701

• mRNA 3' of the A site bound codon is located close to protein S3 on the human 80S ribosome.

  RNA biology 20060701

• Activation of the mu-opiate receptor by Vitex agnus-castus methanol extracts: implication for its use in PMS.

  Journal of ethnopharmacology 20060630

• A novel role for cyclic guanosine 3',5'monophosphate signaling in synaptic plasticity: a selective suppressor of protein kinase A-dependent forms of long-term potentiation.

  Neuroscience 20060630

• 2-[(4-phenylpiperazin-1-yl)methyl]imidazo(di)azines as selective D4-ligands. Induction of penile erection by 2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine (PIP3EA), a potent and selective D4 partial agonist.

  Journal of medicinal chemistry 20060629

• [(35)S]GTPgammaS binding stimulated by endomorphin-2 and morphiceptin analogs.

  Biochemical and biophysical research communications 20060623

• Phototransduction in a transgenic mouse model of Nougaret night blindness.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060621

• Up-regulation of the angiotensin II type 1 receptor by the MAS proto-oncogene is due to constitutive activation of Gq/G11 by MAS.

  The Journal of biological chemistry 20060616

• YC-1 induces S cell cycle arrest and apoptosis by activating checkpoint kinases.

  Cancer research 20060615

• Opioid mu receptor activation inhibits sodium currents in prefrontal cortical neurons via a protein kinase A- and C-dependent mechanism.

  Brain research 20060613

• Three conserved guanosines approach the reaction site in native and minimal hammerhead ribozymes.

  Biochemistry 20060613

• Relevance of brain natriuretic peptide in preload-dependent regulation of cardiac sarcoplasmic reticulum Ca2+ ATPase expression.

  Circulation 20060613

• Reconstitution of recycling from the phagosomal compartment in streptolysin O-permeabilized macrophages: role of Rab11.

  Experimental cell research 20060610

• A conditional mutant deficient in hypoxanthine-guanine phosphoribosyltransferase and xanthine phosphoribosyltransferase validates the purine salvage pathway of Leishmania donovani.

  The Journal of biological chemistry 20060609

• Universal initiator nucleotides for the enzymatic synthesis of 5'-amino- and 5'-thiol-modified RNA.

  Biochemical and biophysical research communications 20060609

• The exocyclic amine at the RNase P cleavage site contributes to substrate binding and catalysis.

  Journal of molecular biology 20060609

• Modified nucleosides: an accurate tumour marker for clinical diagnosis of cancer, early detection and therapy control.

  British journal of cancer 20060605

• The intron 1 of HPV 16 has a suboptimal branch point at a guanosine.

  Virus research 20060601

• Dose-responsive insulin regulation of glucose transport in human skeletal muscle.

  American journal of physiology. Endocrinology and metabolism 20060601

• Thermodynamic properties of enzyme-catalyzed reactions involving guanine, xanthine, and their nucleosides and nucleotides.

  Biophysical chemistry 20060601

• ApoE-epsilon 4-dependent association of the choline acetyltransferase gene polymorphisms (2384G>A and 1882G>A) with Alzheimer's disease.

  Clinica chimica acta; international journal of clinical chemistry 20060601

• In the ventral tegmental area, G-proteins mediate progesterone's actions at dopamine type 1 receptors for lordosis of rats and hamsters.

  Psychopharmacology 20060601

• Identification of the somatostatin receptor subtypes (sst) mediating the divergent, stimulatory/inhibitory actions of somatostatin on growth hormone secretion.

  Endocrinology 20060601

• SB-616234-A (1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2,3-dihydro-5-methoxyindol-1-yl]-1-[2'methyl-4'-(5-methyl-1,2,3-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride): a novel, potent and selective 5-HT1B receptor antagonist.

  Neuropharmacology 20060601

• N-methylpurine DNA glycosylase and 8-oxoguanine dna glycosylase metabolize the antiviral nucleoside 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole.

  Drug metabolism and disposition: the biological fate of chemicals 20060601

• S-nitrosylation of cysteine 289 of the AT1 receptor decreases its binding affinity for angiotensin II.

  British journal of pharmacology 20060601

• Nucleobase catalysis in the hairpin ribozyme.

  RNA (New York, N.Y.) 20060601

• Pathogen-associated molecular patterns are growth and survival factors for human myeloma cells through Toll-like receptors.

  Leukemia 20060601

• Immunohistochemical study of caveolin-1 and -2 in the rat retina.

  Journal of veterinary science 20060601

• A phosphatidylinositol-3-kinase-dependent signal transition regulates ARF1 and ARF6 during Fcgamma receptor-mediated phagocytosis.

  PLoS biology 20060601

• mu opioid and CB1 cannabinoid receptor interactions: reciprocal inhibition of receptor signaling and neuritogenesis.

  British journal of pharmacology 20060601

• Glyceraldehyde-3-phosphate dehydrogenase regulation in Lactococcus lactis ssp. cremoris MG1363 or relA mutant at low pH.

  Journal of applied microbiology 20060601

• A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions.

  Journal of neurochemistry 20060601

• Inflammation and multiple myeloma: the Toll connection.

  Leukemia 20060601

• Molecular dissection of the mycobacterial stringent response protein Rel.

  Protein science : a publication of the Protein Society 20060601

• Endothelin 1 stimulates beta1Pix-dependent activation of Cdc42 through the G(salpha) pathway.

  Experimental biology and medicine (Maywood, N.J.) 20060601

• Involvement of endothelin in morphine tolerance in neuroblastoma (SH-SY5Y) cells.

  Experimental biology and medicine (Maywood, N.J.) 20060601

• Involvement of central endothelin receptors in neonatal morphine withdrawal.

  Experimental biology and medicine (Maywood, N.J.) 20060601

• Insights into the physiology of childbirth using transcriptomics.

  PLoS medicine 20060601

• Rice GTPase OsRacB: potential accessory factor in plant salt-stress signaling.

  Acta biochimica et biophysica Sinica 20060601

• Zinc in the treatment of acute diarrhea: current status and assessment.

  Gastroenterology 20060601

• Effect of oestradiol on PAMP-mediated CCL20/MIP-3 alpha production by mouse uterine epithelial cells in culture.

  Immunology 20060601

• Characterization of a lipid hydroperoxide-derived RNA adduct in rat intestinal epithelial cells.

  Chemical research in toxicology 20060601

• Nucleotide mutations in purA gene and pur operon promoter discovered in guanosine- and inosine-producing Bacillus subtilis strains.

  Biotechnology letters 20060601

• Toll-like receptor agonists stimulate differential functional activation and cytokine and chemokine gene expression in heterophils isolated from chickens with differential innate responses.

  Microbes and infection 20060601

• Improved circadian sleep-wake cycle in infants fed a day/night dissociated formula milk.

  Neuro endocrinology letters 20060601

• Constitutive expression of the human peroxiredoxin V gene contributes to protection of the genome from oxidative DNA lesions and to suppression of transcription of noncoding DNA.

  The FEBS journal 20060601

• Unusual metal specificity and structure of the group I ribozyme from Chlamydomonas reinhardtii 23S rRNA.

  The FEBS journal 20060601

• Biochemical and electrophysiological changes of substantia nigra pars reticulata driven by subthalamic stimulation in patients with Parkinson's disease.

  The European journal of neuroscience 20060601

• Valsartan in the treatment of heart attack survivors.

  Vascular health and risk management 20060601

• Cold virus fusion or stopping fusion cold--inhibitors of the human respiratory syncytial virus F protein.

  Recent patents on anti-infective drug discovery 20060601

• Inconspicuous consumption: uncovering the molecular pathways behind phagocytosis.

  PLoS biology 20060601

• Polymorphism of the signaling molecule c-di-GMP.

  Journal of the American Chemical Society 20060531

• Structure and synthesis of 6-(substituted-imidazol-1-yl)purines: versatile substrates for regiospecific alkylation and glycosylation at N9.

  The Journal of organic chemistry 20060526

• Histamine release, an undesired effect of thrombin inhibitors with basic character, is mediated through direct activation of G(i) proteins.

  European journal of pharmacology 20060524

• Dominant negative mutants of transducin-alpha that block activated receptor.

  Biochemistry 20060523

• Guanophostin A: Synthesis and evaluation of a high affinity agonist of the D-myo-inositol 1,4,5-trisphosphate receptor.

  Chemical communications (Cambridge, England) 20060521

• Efficient synthesis of 2'-C-beta-methylguanosine.

  The Journal of organic chemistry 20060512

• Novel OPA1 mutations identified in Japanese pedigrees with optic atrophy.

  Molecular vision 20060512

• The crystal structure of the apoenzyme of the iron-sulphur cluster-free hydrogenase.

  Journal of molecular biology 20060505

• Cannabinoid system in the budgerigar brain.

  Brain research 20060504

• A pyrazolato-bridged dinuclear platinum(II) complex induces only minor distortions upon DNA-binding.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20060503

• Mutations of CB1 T210 produce active and inactive receptor forms: correlations with ligand affinity, receptor stability, and cellular localization.

  Biochemistry 20060502

• Quantification of oxidized RNAs in Alzheimer's disease.

  Neurobiology of aging 20060501

• Amnesic effect of GMP depends on its conversion to guanosine.

  Neurobiology of learning and memory 20060501

• Differential coupling of the P2Y1 receptor to Galpha14 and Galphaq/11 proteins during the development of the rat salivary gland.

  Archives of oral biology 20060501

• Loss of TRPV1-expressing sensory neurons reduces spinal mu opioid receptors but paradoxically potentiates opioid analgesia.

  Journal of neurophysiology 20060501

• Galanin and galanin-like peptide differentially modulate neuronal activities in rat arcuate nucleus neurons.

  Journal of neurophysiology 20060501

• The high throughput screening of neuropeptide FF2 receptor ligands from Korean herbal plant extracts.

  Peptides 20060501

• Entecavir: a new treatment option for chronic hepatitis B.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20060501

• Interpretation of intramolecular stacking effect on the fluorescence intensity decay of 3-methylbenzimidazolyl(5'-5')guanosine dinucleotides using a model of lifetime distribution.

  European biophysics journal : EBJ 20060501

• Increased phosphodiesterase-5 expression is involved in the decreased vasodilator response to nitric oxide in cirrhotic rat livers.

  Journal of hepatology 20060501

• Cell and tissue responses of a range of Urotensin II analogs at cloned and native urotensin II receptors. Evidence for coupling promiscuity.

  Naunyn-Schmiedeberg's archives of pharmacology 20060501

• Cbfa-1 mediates nitric oxide regulation of MMP-13 in osteoblasts.

  Journal of cell science 20060501

• L-cysteine inhibits insulin release from the pancreatic beta-cell: possible involvement of metabolic production of hydrogen sulfide, a novel gasotransmitter.

  Diabetes 20060501

• Rapid and sensitive real-time polymerase chain reaction method for detection and quantification of 3243A>G mitochondrial point mutation.

  The Journal of molecular diagnostics : JMD 20060501

• Detection of common disease-causing mutations in mitochondrial DNA (mitochondrial encephalomyopathy, lactic acidosis with stroke-like episodes MTTL1 3243 A>G and myoclonic epilepsy associated with ragged-red fibers MTTK 8344A>G) by real-time polymerase chain reaction.

  The Journal of molecular diagnostics : JMD 20060501

• Synthesis and evaluation as NOP ligands of some spiro[piperidine-4,2'(1'H)-quinazolin]-4'(3'H)-ones and spiro[piperidine-4,5'(6'H)-[1,2,4]triazolo[1,5-c]quinazolines].

  Chemical & pharmaceutical bulletin 20060501

• Guanosine and inosine display antioxidant activity, protect DNA in vitro from oxidative damage induced by reactive oxygen species, and serve as radioprotectors in mice.

  Radiation research 20060501

• Airway smooth muscle prostaglandin-EP1 receptors directly modulate beta2-adrenergic receptors within a unique heterodimeric complex.

  The Journal of clinical investigation 20060501

• Elevated levels of urinary 8-hydroxy-2 -deoxyguanosine, lymphocytic micronuclei, and serum glutathione S-transferase in workers exposed to coke oven emissions.

  Environmental health perspectives 20060501

• Delivery of the malaria virulence protein PfEMP1 to the erythrocyte surface requires cholesterol-rich domains.

  Eukaryotic cell 20060501

• Cloning, purification and preliminary crystallographic analysis of the Bacillus subtilis GTPase YphC-GDP complex.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20060501

• Exisulind and guanylyl cyclase C induce distinct antineoplastic signaling mechanisms in human colon cancer cells.

  Molecular cancer therapeutics 20060501

• Distribution of poly(A) RNA and splicing machinery elements in mature Hyacinthus orientalis L. pollen grains and pollen tubes growing in vitro.

  Protoplasma 20060501

• Prolonged treatment with ligands affects ligand binding to the human serotonin(1A) receptor in Chinese hamster ovary cells.

  Cellular and molecular neurobiology 20060501

• Beneficial effects of combined benazepril-amlodipine on cardiac nitric oxide, cGMP, and TNF-alpha production after cardiac ischemia.

  Journal of cardiovascular pharmacology 20060501

• Quality evaluation of Cordyceps through simultaneous determination of eleven nucleosides and bases by RP-HPLC.

  Journal of separation science 20060501

• Guanosine 5'-[gamma-thio]triphosphate-mediated activation of cytosol phospholipase C caused lysosomal destabilization.

  The Journal of membrane biology 20060501

• SB-649915, a novel, potent 5-HT1A and 5-HT1B autoreceptor antagonist and 5-HT re-uptake inhibitor in native tissue.

  European journal of pharmacology 20060424

• Synthesis and CB1 receptor activities of dimethylheptyl derivatives of 2-arachidonoyl glycerol (2-AG) and 2-arachidonyl glyceryl ether (2-AGE).

  Bioorganic & medicinal chemistry 20060415

• Assessment of a high-throughput screening methodology for the measurement of purified UCP1 uncoupling activity.

  Analytical biochemistry 20060415

• Nucleotide exchange via local protein unfolding--structure of Rab8 in complex with MSS4.

  The EMBO journal 20060405

• Supramolecular switches based on the guanine-cytosine (GC) Watson-Crick pair: effect of neutral and ionic substituents.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20060403

• Identification and characterization of a G-protein regulatory motif in WAVE1.

  FEBS letters 20060403

• Heritable differences in the dopaminergic regulation of behavior in rats: relationship to D2-like receptor G-protein function.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060401

• Chronic pain induces anxiety with concomitant changes in opioidergic function in the amygdala.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060401

• Sphingosine-1-phosphate activates BKCa channels independently of G protein-coupled receptor in human endothelial cells.

  American journal of physiology. Cell physiology 20060401

• Involvement of calmodulin and myosin light chain kinase in activation of mTRPC5 expressed in HEK cells.

  American journal of physiology. Cell physiology 20060401

• Mechanisms of ligand binding to the parathyroid hormone (PTH)/PTH-related protein receptor: selectivity of a modified PTH(1-15) radioligand for GalphaS-coupled receptor conformations.

  Molecular endocrinology (Baltimore, Md.) 20060401

• Reaction mechanism and substrate specificity for nucleotide sugar of mammalian alpha1,6-fucosyltransferase--a large-scale preparation and characterization of recombinant human FUT8.

  Glycobiology 20060401

• Distribution of nociceptin and Ro64-6198 activated [35S]-GTPgammaS binding in the rat brain.

  Neuropeptides 20060401

• Discovery of naturally occurring splice variants of the rat histamine H3 receptor that act as dominant-negative isoforms.

  Molecular pharmacology 20060401

• The G12 family of G proteins as a reporter of thromboxane A2 receptor activity.

  Molecular pharmacology 20060401

• On the mechanism of interaction of potent surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2.

  Molecular pharmacology 20060401

• Nitric oxide, a biological double-faced janus--is this good or bad?

  Histology and histopathology 20060401

• Regulation of spontaneous contractile activity in the bovine epididymal duct by cyclic guanosine 5'-monophosphate-dependent pathways.

  Endocrinology 20060401

• Big dynorphin as a putative endogenous ligand for the kappa-opioid receptor.

  Journal of neurochemistry 20060401

• Mu-opioid receptors are involved in the tolerance to nicotine antinociception.

  Journal of neurochemistry 20060401

• Proteomic analyses of Oryza sativa mature pollen reveal novel proteins associated with pollen germination and tube growth.

  Proteomics 20060401

• Radioligand binding and functional responses of ligands for human recombinant adenosine A(3) receptors.

  Autonomic & autacoid pharmacology 20060401

• A gene involved in modifying transfer RNA is required for fungal pathogenicity and stress tolerance of Colletotrichum lagenarium.

  Molecular microbiology 20060401

• Role of mitochondrial superoxide dismutase in the development of diabetic retinopathy.

  Investigative ophthalmology & visual science 20060401

• Halothane does not inhibit the functional coupling between the beta2-adrenergic receptor and the Galphas heterotrimeric G protein.

  Anesthesiology 20060401

• Mucosal immunization with a urease B DNA vaccine induces innate and cellular immune responses against Helicobacter pylori.

  Helicobacter 20060401

• Effect of L-arginine therapy on the glomerular injury of preeclampsia: a randomized controlled trial.

  Obstetrics and gynecology 20060401

• Photooxidation of acyclovir with thermally generated triplet excited ketones. A comparison with type I and II photosensitizers.

  Chemical & pharmaceutical bulletin 20060401

• Identification and classification of conserved RNA secondary structures in the human genome.

  PLoS computational biology 20060401

• Evidence for a role of CaMKIV in the development of opioid analgesic tolerance.

  The European journal of neuroscience 20060401

• Role of protein kinase C, G-protein coupled receptors, and calcium flux during metamorphosis of the sea urchin Strongylocentrotus purpuratus.

  The Biological bulletin 20060401

• An innovative cell-based assay for the detection of modulators of soluble guanylate cyclase.

  Assay and drug development technologies 20060401

• Partial agonist properties of the antipsychotics SSR181507, aripiprazole and bifeprunox at dopamine D2 receptors: G protein activation and prolactin release.

  European journal of pharmacology 20060327

• Identity elements required for enzymatic formation of N2,N2-dimethylguanosine from N2-monomethylated derivative and its possible role in avoiding alternative conformations in archaeal tRNA.

  Journal of molecular biology 20060324

• Synthesis, structures, and electrochemistry of gold(III) ethylenediamine complexes and interactions with guanosine 5'-monophosphate.

  Inorganic chemistry 20060320

• Conformational changes associated with receptor-stimulated guanine nucleotide exchange in a heterotrimeric G-protein alpha-subunit: NMR analysis of GTPgammaS-bound states.

  The Journal of biological chemistry 20060317

• The RNA-binding PUA domain of archaeal tRNA-guanine transglycosylase is not required for archaeosine formation.

  The Journal of biological chemistry 20060317

• Acquisition of the wobble modification in mitochondrial tRNALeu(CUN) bearing the G12300A mutation suppresses the MELAS molecular defect.

  Human molecular genetics 20060315

• Increased opioid receptor binding and G protein coupling in the accumbens and ventral tegmental area of postnatal day 2 rats.

  Neuroscience letters 20060313

• The N terminus of GTP gamma S-activated transducin alpha-subunit interacts with the C terminus of the cGMP phosphodiesterase gamma-subunit.

  The Journal of biological chemistry 20060310

• Neonatal 3,4-methylenedioxymethamphetamine (MDMA) exposure alters neuronal protein kinase A activity, serotonin and dopamine content, and [35S]GTPgammaS binding in adult rats.

  Brain research 20060310

• N-substituted 4beta-methyl-5-(3-hydroxyphenyl)-7alpha-amidomorphans are potent, selective kappa opioid receptor antagonists.

  Journal of medicinal chemistry 20060309

• A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B.

  The New England journal of medicine 20060309

• Determination of antiviral nucleoside analogues AM365 and AM188 in perfusate and bile of the isolated perfused rat liver using HPLC.

  Biomedical chromatography : BMC 20060301

• Profile of Toll-like receptor expressions and induction of nitric oxide synthesis by Toll-like receptor agonists in chicken monocytes.

  Molecular immunology 20060301

• Nitrative DNA damage in inflammation and its possible role in carcinogenesis.

  Nitric oxide : biology and chemistry 20060301

• Genetic manipulation of two fowlpox virus late transcriptional regulatory elements influences their ability to direct expression of foreign genes.

  Virus research 20060301

• Differential efficacies of somatostatin receptor agonists for G-protein activation and desensitization of somatostatin receptor subtype 4-mediated responses.

  The Journal of pharmacology and experimental therapeutics 20060301

• Comparison of the antinociceptive response to morphine and morphine-like compounds in male and female Sprague-Dawley rats.

  The Journal of pharmacology and experimental therapeutics 20060301

• Nitrative stress through formation of 8-nitroguanosine: insights into microbial pathogenesis.

  Nitric oxide : biology and chemistry 20060301

• Leishmania amazonensis: chemotaxic and osmotaxic responses in promastigotes and their probable role in development in the phlebotomine gut.

  Experimental parasitology 20060301

• Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo.

  Molecular therapy : the journal of the American Society of Gene Therapy 20060301

• Effect of trimetazidine on the nucleotide profile in rat kidney with ischemia-reperfusion injury.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060301

• G protein-associated, specific membrane binding sites mediate the neuroprotective effect of dehydroepiandrosterone.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301

• The basic secretagogue compound 48/80 activates G proteins indirectly via stimulation of phospholipase D-lysophosphatidic acid receptor axis and 5-HT1A receptors in rat brain sections.

  British journal of pharmacology 20060301

• Differential activation of G-proteins by mu-opioid receptor agonists.

  British journal of pharmacology 20060301

• Seasonal changes of nucleotides in mussel (Mytilus galloprovincialis) mantle tissue.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20060301

• GTP drives myosin light chain 1 interaction with the class V myosin Myo2 IQ motifs via a Sec2 RabGEF-mediated pathway.

  Molecular microbiology 20060301

• Role of nitric oxide in the relaxation elicited by sildenafil in penile resistance arteries.

  The Journal of urology 20060301

• Specific functional interactions of nucleotides at key -3 and +4 positions flanking the initiation codon with components of the mammalian 48S translation initiation complex.

  Genes & development 20060301

• Synthesis of oligodeoxynucleotides containing a single 6alpha- or 6beta-diastereoisomer of N2-(estradiol-6-yl)-2'-deoxyguanosine.

  Chemical research in toxicology 20060301

• Mu-opioid receptor cellular function in the nucleus accumbens is essential for hedonically driven eating.

  The European journal of neuroscience 20060301

• Influence of a high carbohydrate diet on the functional activity of 5-HT1B/1D receptors on human peripheral blood lymphocytes during intense military training.

  European cytokine network 20060301

• Suppression of food intake and food-reinforced behavior produced by the novel CB1 receptor antagonist/inverse agonist AM 1387.

  Pharmacology, biochemistry, and behavior 20060301

• An efficient process for synthesis of 2'-O-methyl and 3'-O-methyl guanosine from 2-aminoadenosine using diazomethane and the catalyst stannous chloride.

  Nucleosides, nucleotides & nucleic acids 20060301

• An industrial process for selective synthesis of 7-methyl guanosine 5'-diphosphate: versatile synthon for synthesis of mRNA cap analogues.

  Nucleosides, nucleotides & nucleic acids 20060301

• Topical non-iontophoretic application of acetylcholine and nitroglycerin via a translucent patch: a new means for assessing microvascular reactivity.

  The Yale journal of biology and medicine 20060301

• Pharmacological manipulation of cyclic GMP levels in brain restores learning ability in animal models of hepatic encephalopathy: therapeutic implications.

  Neuropsychiatric disease and treatment 20060301

• Nomenclature for the human Arf family of GTP-binding proteins: ARF, ARL, and SAR proteins.

  The Journal of cell biology 20060227

• Differential phosphorylation of the rhodopsin cytoplasmic tail mediates the binding of arrestin and its splice variant, p44.

  Biochemistry 20060221

• Lipid and peptide control of phosphatidylinositol 4-kinase IIalpha activity on Golgi-endosomal Rafts.

  The Journal of biological chemistry 20060217

• Comparison of the in vitro efficacy of mu, delta, kappa and ORL1 receptor agonists and non-selective opioid agonists in dog brain membranes.

  Brain research 20060216

• [35S]GTPgammaS binding at the human dopamine D4 receptor variants hD4.2, hD4.4 and hD4.7 following stimulation by dopamine, epinephrine and norepinephrine.

  European journal of pharmacology 20060215

• Position-dependent repression and promotion of DQB1 intron 3 splicing by GGGG motifs.

  Journal of immunology (Baltimore, Md. : 1950) 20060215

• Illuminated rhodopsin is required for strong activation of retinal guanylate cyclase by guanylate cyclase-activating proteins.

  Biochemistry 20060214

• Guanosine 3',5'-bispyrophosphate coordinates global gene expression during glucose-lactose diauxie in Escherichia coli.

  Proceedings of the National Academy of Sciences of the United States of America 20060214

• No change in cortical muscarinic M2, M3 receptors or [35S]GTPgammaS binding in schizophrenia.

  Life sciences 20060209

• Use of probes with fluorescence indicator distributed throughout the pharmacophore to examine the peptide agonist-binding environment of the family B G protein-coupled secretin receptor.

  The Journal of biological chemistry 20060203

• Improved synthesis of 2'-amino-2'-deoxyguanosine and its phosphoramidite.

  Bioorganic & medicinal chemistry 20060201

• Identification of an achiral analogue of J-113397 as potent nociceptin/orphanin FQ receptor antagonist.

  Bioorganic & medicinal chemistry 20060201

• Cyclic guanosine 5'-monophosphate-dependent protein kinase II is induced by luteinizing hormone and progesterone receptor-dependent mechanisms in granulosa cells and cumulus oocyte complexes of ovulating follicles.

  Molecular endocrinology (Baltimore, Md.) 20060201

• A novel cannabinoid peripheral cannabinoid receptor-selective inverse agonist blocks leukocyte recruitment in vivo.

  The Journal of pharmacology and experimental therapeutics 20060201

• Immunomodulatory effects of Toll-like receptor-7 activation on chronic lymphocytic leukemia cells.

  Leukemia 20060201

• The 'allosteric modulator' SCH-202676 disrupts G protein-coupled receptor function via sulphydryl-sensitive mechanisms.

  British journal of pharmacology 20060201

• Agonist activity of naloxone benzoylhydrazone at recombinant and native opioid receptors.

  British journal of pharmacology 20060201

• Differential immune effects mediated by Toll-like receptors stimulation in precursor B-cell acute lymphoblastic leukaemia.

  British journal of haematology 20060201

• Sequence-specific recognition of RNA hairpins by the SAM domain of Vts1p.

  Nature structural & molecular biology 20060201

• Markers of oxidative stress in placental villi exposed to ethanol.

  Journal of the Society for Gynecologic Investigation 20060201

• A metabolic study of patients with lung cancer and hyponatremia of malignancy.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20060201

• 5-HT-stimulated [35S]guanosine-5'-O-(3-thio)triphosphate binding as an assay for functional activation of G proteins coupled with 5-HT1B receptors in rat striatal membranes.

  Naunyn-Schmiedeberg's archives of pharmacology 20060201

• IMP dehydrogenase inhibitor mycophenolate mofetil induces caspase-dependent apoptosis and cell cycle inhibition in multiple myeloma cells.

  Molecular cancer therapeutics 20060201

• Catecholaminergic activation of G-protein coupling in rat spinal cord: further evidence for the existence of dopamine and noradrenaline receptors in spinal grey and white matter.

  Brain research 20060127

• Phospholipase Cbeta1 modulates pain sensitivity, opioid antinociception and opioid tolerance formation.

  Brain research 20060119

• Natriuretic peptides, but not nitric oxide donors, elevate levels of cytosolic guanosine 3',5'-cyclic monophosphate in ependymal cells ex vivo.

  Neuroscience letters 20060116

• GABA(B) receptor function and subunit expression in the rat spinal cord as indicators of stress and the antinociceptive response to antidepressants.

  Brain research 20060112

• A unimolecular G-quadruplex that functions as a synthetic transmembrane Na+ transporter.

  Journal of the American Chemical Society 20060111

• Single transmembrane domain insulin-like growth factor-II/mannose-6-phosphate receptor regulates central cholinergic function by activating a G-protein-sensitive, protein kinase C-dependent pathway.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060111

• Regulation of the interaction of inosine monophosphate dehydrogenase with mycophenolic Acid by GTP.

  The Journal of biological chemistry 20060106

• Molecular basis for nucleotide-binding specificity: role of the exocyclic amino group 'N2' in recognition by a guanylyl-ribonuclease.

  Journal of molecular biology 20060106

• 7-Functionalized 7-deazapurine ribonucleosides related to 2-aminoadenosine, guanosine, and xanthosine: glycosylation of pyrrolo[2,3-d]pyrimidines with 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribofuranose.

  The Journal of organic chemistry 20060106

• Effects of the perfusion flow rate on skeletal muscle energy metabolism and a possible role of second messengers in this process.

  Physiological research 20060101

• Constitutively active micro opioid receptors mediate the enhanced conditioned aversive effect of naloxone in morphine-dependent mice.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060101

• A docking site for G protein βγ subunits on the parathyroid hormone 1 receptor supports signaling through multiple pathways.

  Molecular endocrinology (Baltimore, Md.) 20060101

• Purine and pyrimidine metabolism and electrocortical brain activity during hypotension in near-term lambs.

  Biology of the neonate 20060101

• Relationship between activating and editing functions of the adenylation domain of apo-tyrocidin synthetase 1 (apo-TY1).

  Biochimie 20060101

• The carboxyl terminus of the Galpha-subunit is the latch for triggered activation of heterotrimeric G proteins.

  Molecular pharmacology 20060101

• The reaction of water with guanosine radical cation in DNA.

  Photochemistry and photobiology 20060101

• A delayed ATP-elicited K+ current in freshly isolated smooth muscle cells from mouse aorta.

  British journal of pharmacology 20060101

• Treating HCV with ribavirin analogues and ribavirin-like molecules.

  The Journal of antimicrobial chemotherapy 20060101

• Radical production and DNA damage induced by carcinogenic 4-hydrazinobenzoic acid, an ingredient of mushroom Agaricus bisporus.

  Free radical research 20060101

• Base-pairing potential identified by in vitro selection predicts the kinked RNA backbone observed in the crystal structure of the alfalfa mosaic virus RNA-coat protein complex.

  Journal of molecular recognition : JMR 20060101

• Effect of long-term phosphate starvation on the levels and metabolism of purine nucleotides in suspension-cultured Catharanthus roseus cells.

  Phytochemistry 20060101

• Subtle but variable conformational rearrangements in the replication cycle of Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4) may accommodate lesion bypass.

  Protein science : a publication of the Protein Society 20060101

• Hydrogen peroxide causes uncoupling of dopamine D1-like receptors from G proteins via a mechanism involving protein kinase C and G-protein-coupled receptor kinase 2.

  Free radical biology & medicine 20060101

• 18F-FEAU as a radiotracer for herpes simplex virus thymidine kinase gene expression: in-vitro comparison with other PET tracers.

  Nuclear medicine communications 20060101

• New horizons for (p)ppGpp in bacterial and plant physiology.

  Trends in microbiology 20060101

• Azathioprine suppresses ezrin-radixin-moesin-dependent T cell-APC conjugation through inhibition of Vav guanosine exchange activity on Rac proteins.

  Journal of immunology (Baltimore, Md. : 1950) 20060101

• Biosynthesis of cellulose-enriched tension wood in Populus: global analysis of transcripts and metabolites identifies biochemical and developmental regulators in secondary wall biosynthesis.

  The Plant journal : for cell and molecular biology 20060101

• Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.

  PLoS biology 20060101

• Age-related emotionality is associated with cortical delta-opioid receptor dysfunction-dependent astrogliosis.

  Neuroscience 20060101

• MazG -- a regulator of programmed cell death in Escherichia coli.

  Molecular microbiology 20060101

• Effect of vardenafil, an inhibitor of phosphodiesterase-5, on portal haemodynamics in normal and cirrhotic liver -- results of a pilot study.

  Alimentary pharmacology & therapeutics 20060101

• Nitroglycerin reperfusion reduces ischemia-reperfusion injury in non-heart-beating donor lungs.

  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060101

• N2-carboxyethyl-2'-deoxyguanosine, a DNA glycation marker, in kidneys and aortas of diabetic and uremic patients.

  Kidney international 20060101

• The greater reactivity of estradiol-3,4-quinone vs estradiol-2,3-quinone with DNA in the formation of depurinating adducts: implications for tumor-initiating activity.

  Chemical research in toxicology 20060101

• Spinal nerve ligation does not alter the expression or function of GABA(B) receptors in spinal cord and dorsal root ganglia of the rat.

  Neuroscience 20060101

• Molecular phylogenetics and comparative modeling of HEN1, a methyltransferase involved in plant microRNA biogenesis.

  BMC evolutionary biology 20060101

• Efficient synthesis of [2-15N]guanosine and 2'-deoxy[2'-15N]guanosine derivatives using N-(tert-butyldimethylsilyl)[15N]phthalimide as a 15N-labeling reagent.

  Nucleosides, nucleotides & nucleic acids 20060101

• Purification of P-Rex1 from neutrophils and nucleotide exchange assay.

  Methods in enzymology 20060101

• Phosphorylation of RhoGDI by p21-activated kinase 1.

  Methods in enzymology 20060101

• Highly expressed proteins have an increased frequency of alanine in the second amino acid position.

  BMC genomics 20060101

• A method to determine RNA and DNA oxidation simultaneously by HPLC-ECD: greater RNA than DNA oxidation in rat liver after doxorubicin administration.

  Biological chemistry 20060101

• Macrophage migration inhibitory factor induces cell death and decreases neuronal nitric oxide expression in spinal cord neurons.

  Neuroscience 20060101

• Cannabinoid receptor binding to membrane homogenates and cannabinoid-stimulated [35S]GTPgammaS binding to membrane homogenates or intact cultured cells.

  Methods in molecular medicine 20060101

• Quantification of benzo[a]pyrene diol epoxide DNA-adducts by stable isotope dilution liquid chromatography/tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20060101

• Uneven distribution of nucleoside transporters and intracellular enzymatic degradation prevent transport of intact [14C] adenosine across the sheep choroid plexus epithelium as a monolayer in primary culture.

  Cerebrospinal fluid research 20060101

• Changes in ion transport in inflammatory disease.

  Journal of inflammation (London, England) 20060101

• Rac2 concentrations in umbilical cord neutrophils.

  Biology of the neonate 20060101

• Thalidomide attenuates nitric oxide mediated angiogenesis by blocking migration of endothelial cells.

  BMC cell biology 20060101

• Prevention and treatment of recurrent Hepatitis B after liver transplantation: the current role of nucleoside and nucleotide analogues.

  Annals of clinical microbiology and antimicrobials 20060101

• Synaptic depression and short-term habituation are located in the sensory part of the mammalian startle pathway.

  BMC neuroscience 20060101

• Improvement of bioprocess monitoring: development of novel concepts.

  Microbial cell factories 20060101

• Rational drug design of selective epsilon opioid receptor agonist TAN-821 and antagonist TAN-1014.

  Current medicinal chemistry 20060101

• Intervention of Toll-like receptor-mediated human innate immunity and inflammation by synthetic compounds and naturally occurring products.

  Current medicinal chemistry 20060101

• 8-nitroguanine, a product of nitrative DNA damage caused by reactive nitrogen species: formation, occurrence, and implications in inflammation and carcinogenesis.

  Antioxidants & redox signaling 20060101

• Guanosine and inosine as natural antioxidants and radioprotectors for mice exposed to lethal doses of gamma-radiation.

  Doklady. Biochemistry and biophysics 20060101

• Transcriptome analysis of Deinagkistrodon acutus venomous gland focusing on cellular structure and functional aspects using expressed sequence tags.

  BMC genomics 20060101

• Analysis of EGF receptor interactions with the alpha subunit of the stimulatory GTP binding protein of adenylyl cyclase, Gs.

  Methods in molecular biology (Clifton, N.J.) 20060101

• Molecular pathopharmacology of 5-HT2C receptors and the RNA editing in the brain.

  Journal of pharmacological sciences 20060101

• Protection against esophageal cancer in rodents with lyophilized berries: potential mechanisms.

  Nutrition and cancer 20060101

• Singlet oxygen oxidation of isolated and cellular DNA: product formation and mechanistic insights.

  Photochemistry and photobiology 20060101

• Functional coupling of the Galpha(olf) variant XLGalpha(olf) with the human adenosine A2A receptor.

  Journal of receptor and signal transduction research 20060101

• Epidemiology, risk factors, and lifestyle modifications for gout.

  Arthritis research & therapy 20060101

• Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics.

  Arthritis research & therapy 20060101

• Lung epithelium as a sentinel and effector system in pneumonia--molecular mechanisms of pathogen recognition and signal transduction.

  Respiratory research 20060101

• P2Y2 receptor up-regulation induced by guanosine or UTP in rat brain cultured astrocytes.

  International journal of immunopathology and pharmacology 20060101

• In vitro binding and functional studies of Ac-RYYRIK-ol and its derivatives, novel partial agonists of the nociceptin/orphanin F/Q receptor.

  Neuro-Signals 20060101

• Characterization of constitutively active mutants of G protein-coupled receptors.

  Methods in molecular biology (Clifton, N.J.) 20060101

• Reconstitution system based on cytosol-depleted cells to study the regulation of phospholipase D.

  Methods in molecular biology (Clifton, N.J.) 20060101

• Does WAVE1 contain a GoLoco/GPR motif?

  International journal of biological sciences 20060101

• Concentration of nucleosides and related compounds in cerebral and cerebellar cortical areas and white matter of the human brain.

  Cellular and molecular neurobiology 20060101

• Synthesis of 2'-amino-LNA purine nucleosides.

  Nucleosides, nucleotides & nucleic acids 20060101

• Trimethylguanosine nucleoside inhibits cross-linking between Snurportin 1 and m3G-CAPPED U1 snRNA.

  Nucleosides, nucleotides & nucleic acids 20060101

• Structure of the biologically relevant G-quadruplex in the c-MYC promoter.

  Nucleosides, nucleotides & nucleic acids 20060101

• Consequences of low birthweight on urinary excretion of DNA markers of oxidative stress in young men.

  Scandinavian journal of clinical and laboratory investigation 20060101

• Nuclear import of spliceosomal snRNPs.

  Canadian journal of physiology and pharmacology 20060101

• Regulation of the crossbridge cycle in vascular smooth muscle by cAMP signalling.

  Journal of muscle research and cell motility 20060101

• Recording long-term potentiation of synaptic transmission by three-dimensional multi-electrode arrays.

  BMC neuroscience 20060101

• Analysis of signal transduction: formation of cAMP, cGMP, and Ins(1,4,5)P3 in vivo and in vitro.

  Methods in molecular biology (Clifton, N.J.) 20060101

• Global gene expression during stringent response in Corynebacterium glutamicum in presence and absence of the rel gene encoding (p)ppGpp synthase.

  BMC genomics 20060101

• Short G-rich oligonucleotides as a potential therapeutic for Huntington's Disease.

  BMC neuroscience 20060101

• Recent advances in the bcr-abl negative chronic myeloproliferative diseases.

  Journal of translational medicine 20060101

• New insight into the role of phosphodiesterase 3A in porcine oocyte maturation.

  BMC developmental biology 20060101

• TasA-tasB, a new putative toxin-antitoxin (TA) system from Bacillus thuringiensis pGI1 plasmid is a widely distributed composite mazE-doc TA system.

  BMC genomics 20060101

• Inhibition of hepatitis C replicon RNA synthesis by beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine: a specific inhibitor of hepatitis C virus replication.

  Antiviral chemistry & chemotherapy 20060101

• The eggshell is required for meiotic fidelity, polar-body extrusion and polarization of the C. elegans embryo.

  BMC biology 20060101

• Generation of RNAi libraries for high-throughput screens.

  Journal of biomedicine & biotechnology 20060101

• Guanosine analog in the pyrido[2,3-d]pyrimidine ring system as a potential toll-like receptor agonist.

  Nucleosides, nucleotides & nucleic acids 20060101

• RiboSubstrates: a web application addressing the cleavage specificities of ribozymes in designated genomes.

  BMC bioinformatics 20060101

• methBLAST and methPrimerDB: web-tools for PCR based methylation analysis.

  BMC bioinformatics 20060101

• Antifibrotic actions of mycophenolic acid.

  Clinical transplantation 20060101

• The conserved protein kinase-A target motif in synapsin of Drosophila is effectively modified by pre-mRNA editing.

  BMC neuroscience 20060101

• Systematic assignment of thermodynamic constraints in metabolic network models.

  BMC bioinformatics 20060101

• Genetic polymorphisms of MMP1, MMP3 and MMP7 gene promoter and risk of colorectal adenoma.

  BMC cancer 20060101

• The pulmonary effects of intravenous adenosine in asthmatic subjects.

  Respiratory research 20060101

• A strategy for selective N-acylation of purine and pyrimidine bases of deoxy and ribo nucleosides.

  Nucleic acids symposium series (2004) 20060101

• Fluorescence detection of 8-oxoguanosine by G-clamp derivatives.

  Nucleic acids symposium series (2004) 20060101

• Ribonucleome analysis identified enzyme genes responsible for wybutosine synthesis.

  Nucleic acids symposium series (2004) 20060101

• Systematic review and meta-analysis of randomised trials and cohort studies of mycophenolate mofetil in lupus nephritis.

  Arthritis research & therapy 20060101

• Purine nucleoside analogs as immunosuppressive and antineoplastic agents: mechanism of action and clinical activity.

  Current medicinal chemistry 20060101

• Comparative analysis of hepatitis C virus phylogenies from coding and non-coding regions: the 5' untranslated region (UTR) fails to classify subtypes.

  Virology journal 20060101

• The release of nitric oxide from S-nitrosothiols promotes angiogenesis.

  PloS one 20060101

• Human coronavirus 229E encodes a single ORF4 protein between the spike and the envelope genes.

  Virology journal 20060101

• Array-CGH and multipoint FISH to decode complex chromosomal rearrangements.

  BMC genomics 20060101

• Significance of 8-oxoG in the spectrum of DNA damages caused by ionising radiation of different quality.

  Radiation protection dosimetry 20060101

• [Guanosine and inosine as natural geneprotectors for mice blood cells exposed to X-rays].

  Radiatsionnaia biologiia, radioecologiia 20060101

• Conjugates of phthalocyanines with oligonucleotides as reagents for sensitized or catalytic DNA modification.

  Bioinorganic chemistry and applications 20060101

• N-substituted cis-4a-(3-hydroxyphenyl)-8a-methyloctahydroisoquinolines are opioid receptor pure antagonists.

  Journal of medicinal chemistry 20051229

• A quadruply hydrogen bonded heterocomplex displaying high-fidelity recognition.

  Journal of the American Chemical Society 20051228

• Competition between glutathione and guanine for a ruthenium(II) arene anticancer complex: detection of a sulfenato intermediate.

  Journal of the American Chemical Society 20051221

• Differential interactions of G-proteins and adenylyl cyclase with nucleoside 5'-triphosphates, nucleoside 5'-[gamma-thio]triphosphates and nucleoside 5'-[beta,gamma-imido]triphosphates.

  Biochemical pharmacology 20051219

• Sequence dependence of charge transport through DNA domains.

  Journal of the American Chemical Society 20051214

• Transducin activation state controls its light-dependent translocation in rod photoreceptors.

  The Journal of biological chemistry 20051209

• Molecular characterization of the gerbil C5a receptor and identification of a transmembrane domain V amino acid that is crucial for small molecule antagonist interaction.

  The Journal of biological chemistry 20051209

• Identification of 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids as ligands of the G protein-coupled receptor G2A.

  The Journal of biological chemistry 20051209

• Differential ion current activation by human 5-HT(1A) receptors in Xenopus oocytes: evidence for agonist-directed trafficking of receptor signalling.

  Neuropharmacology 20051201

• Two sequential phosphates 3' adjacent to the 8-oxoguanosine are crucial for lesion excision by E. coli Fpg protein and human 8-oxoguanine-DNA glycosylase.

  Biochimie 20051201

• Nalmefene induced elevation in serum prolactin in normal human volunteers: partial kappa opioid agonist activity?

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20051201

• Ontogeny of central melatonin receptors in tadpoles of the anuran Rana perezi: modulation of dopamine release.

  Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20051201

• Short-term plasticity of Bergmann glial cell extrasynaptic currents during parallel fiber stimulation in rat cerebellum.

  Glia 20051201

• Serotonin mediates learning-induced potentiation of excitability.

  Journal of neurophysiology 20051201

• Selective type 5 phosphodiesterase inhibition alters pulmonary hemodynamics and lung liquid production in near-term fetal lambs.

  Journal of applied physiology (Bethesda, Md. : 1985) 20051201

• Modulation of agonist binding to human dopamine receptor subtypes by L-prolyl-L-leucyl-glycinamide and a peptidomimetic analog.

  The Journal of pharmacology and experimental therapeutics 20051201

• Identification of novel mediators of NF-kappaB through genome-wide survey of monocyte adherence-induced genes.

  Journal of leukocyte biology 20051201

• Evidence that the plant cannabinoid Delta9-tetrahydrocannabivarin is a cannabinoid CB1 and CB2 receptor antagonist.

  British journal of pharmacology 20051201

• Complexation of antimony (Sb(V)) with guanosine 5'-monophosphate and guanosine 5'-diphospho-D-mannose: formation of both mono- and bis-adducts.

  Journal of inorganic biochemistry 20051201

• Sustained pharmacological blockade of NK1 substance P receptors causes functional desensitization of dorsal raphe 5-HT 1A autoreceptors in mice.

  Journal of neurochemistry 20051201

• Induction of inclusion formation and disruption of lamin A/C structure by premutation CGG-repeat RNA in human cultured neural cells.

  Human molecular genetics 20051201

• The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif.

  Nature structural & molecular biology 20051201

• Oxidative stress contributes to the enhanced expression of Gialpha proteins and adenylyl cyclase signaling in vascular smooth muscle cells from spontaneously hypertensive rats.

  Journal of hypertension 20051201

• ATP- and adenosine-induced relaxation of the smooth muscle of the pig urethra.

  BJU international 20051201

• Multiple interaction sites of galnon trigger its biological effects.

  Neuropeptides 20051201

• Rho guanosine diphosphate-dissociation inhibitor plays a negative modulatory role in glucose-stimulated insulin secretion.

  Diabetes 20051201

• Interruption of homologous desensitization in cyclic guanosine 3',5'-monophosphate signaling restores colon cancer cytostasis by bacterial enterotoxins.

  Cancer research 20051201

• Biophysical properties of voltage-gated Na+ channels in frog parathyroid cells and their modulation by cannabinoids.

  The Journal of experimental biology 20051201

• Guanosine triphosphatase activation occurs downstream of calcineurin in cardiac hypertrophy*.

  Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20051201

• Quantitation of four guanine oxidation products from reaction of DNA with varying doses of peroxynitrite.

  Chemical research in toxicology 20051201

• 3-Hydrogenkwadaphnin from Dendrostellera lessertii induces differentiation and apoptosis in HL-60 cells.

  Planta medica 20051201

• The development of an europium-GTP assay to quantitate chemokine antagonist interactions for CXCR4 and CCR5.

  Assay and drug development technologies 20051201

• [Natriuretic peptides: a new lipolytic pathway in human fat cells].

  Medecine sciences : M/S 20051201

• Oxidised guanidinohydantoin (Ghox) and spiroiminodihydantoin (Sp) are major products of iron- and copper-mediated 8-oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanosine oxidation.

  Molecular bioSystems 20051201

• Endogenous opioid analgesia in peripheral tissues and the clinical implications for pain control.

  Therapeutics and clinical risk management 20051201

• First joint Italian-German purine club meeting 'Progress in Purinergic Receptor Pharmacology and Function'.

  Purinergic signalling 20051201

• Isozyme-specific stimulation of phospholipase C-gamma2 by Rac GTPases.

  The Journal of biological chemistry 20051125

• Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins.

  Current biology : CB 20051122

• A role for the distal carboxyl tails in generating the novel pharmacology and G protein activation profile of mu and delta opioid receptor hetero-oligomers.

  The Journal of biological chemistry 20051118

• Species-specific identification of mycobacterial 16S rRNA PCR amplicons using smart probes.

  Analytical chemistry 20051115

• Heterotrimeric G-protein alpha-subunit adopts a 'preactivated' conformation when associated with betagamma-subunits.

  The Journal of biological chemistry 20051111

• Discovery of a gene family critical to wyosine base formation in a subset of phenylalanine-specific transfer RNAs.

  The Journal of biological chemistry 20051111

• Direct NMR detection of the 'invisible' alkali metal cations tightly bound to G-quadruplex structures.

  Biochemical and biophysical research communications 20051111

• Direct experimental observation of the effect of the base pairing on the oxidation potential of Guanine.

  Journal of the American Chemical Society 20051102

• Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity.

  The Journal of pharmacology and experimental therapeutics 20051101

• Expression of human 8-oxoguanine DNA glycosylase (hOGG1) in follicular lymphoma.

  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20051101

• Characterization of a novel bivalent morphinan possessing kappa agonist and micro agonist/antagonist properties.

  The Journal of pharmacology and experimental therapeutics 20051101

• Molecular mechanisms involved in the asymmetric interaction between cannabinoid and opioid systems.

  Psychopharmacology 20051101

• 3-Hydrogenkwadaphnin targets inosine 5'-monophosphate dehydrogenase and triggers post-G1 arrest apoptosis in human leukemia cell lines.

  The international journal of biochemistry & cell biology 20051101

• Allosteric modulation of the cannabinoid CB1 receptor.

  Molecular pharmacology 20051101

• Simultaneous high performance liquid chromatographic separation of purines, pyrimidines, N-acetylated amino acids, and dicarboxylic acids for the chemical diagnosis of inborn errors of metabolism.

  Clinical biochemistry 20051101

• Sodium valproate inhibits glucose transport and exacerbates Glut1-deficiency in vitro.

  Journal of cellular biochemistry 20051101

• Broad-spectrum inhibitor of viruses in the Flaviviridae family.

  Antiviral research 20051101

• Dopamine modulates voltage-activated potassium currents in zebrafish retinal on bipolar cells.

  Journal of neuroscience research 20051101

• Urinary cyclic guanosine 3',5'-monophosphate and cyclic adenosine 3',5'-monophosphate changes in spontaneous and induced onset active labor.

  Acta obstetricia et gynecologica Scandinavica 20051101

• Syn-full behavior by T7 DNA polymerase.

  Structure (London, England : 1993) 20051101

• A lysine residue in the fingers subdomain of T7 DNA polymerase modulates the miscoding potential of 8-oxo-7,8-dihydroguanosine.

  Structure (London, England : 1993) 20051101

• Stability and association with the cytomatrix of mitochondrial DNA in spontaneously immortalized mouse embryo fibroblasts containing or lacking the intermediate filament protein vimentin.

  DNA and cell biology 20051101

• Oxidative stress defense mechanisms to counter iron-promoted DNA damage in Helicobacter pylori.

  Free radical research 20051101

• [Effects of tamoxifen on the voltage-dependent ionic currents in mouse colonic smooth muscle cells].

  The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20051101

• [Chloroplast ppGpp synthesis system].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20051101

• [High intestinal transport activity for nucleosides in cattle: a synopsis].

  DTW. Deutsche tierarztliche Wochenschrift 20051101

• Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein.

  The Journal of biological chemistry 20051028

• Apoptosis induced by nucleosides in the human hepatoma HepG2.

  World journal of gastroenterology 20051028

• Conformations of nucleotides bound to wild type and Y78F mutant yeast guanylate kinase: proton two-dimensional transferred NOESY measurements.

  Biochemistry 20051025

• A switch 3 point mutation in the alpha subunit of transducin yields a unique dominant-negative inhibitor.

  The Journal of biological chemistry 20051021

• The role of canonical transient receptor potential 7 in B-cell receptor-activated channels.

  The Journal of biological chemistry 20051021

• Requirement of 8-mercaptoguanosine as a costimulus for IL-4-dependent mu to gamma1 class switch recombination in CD38-activated B cells.

  Biochemical and biophysical research communications 20051021

• Optimizing control of simulated moving beds--experimental implementation.

  Journal of chromatography. A 20051021

• SERS studies of the adsorption of guanine derivatives on gold colloidal nanoparticles.

  Physical chemistry chemical physics : PCCP 20051021

• COMT Val108/158Met genotype affects the mu-opioid receptor system in the human brain: evidence from ligand-binding, G-protein activation and preproenkephalin mRNA expression.

  NeuroImage 20051015

• Post mortem degradation of nucleosides in the brain: comparison of human and rat brains for estimation of in vivo concentration of nucleosides.

  Journal of neuroscience methods 20051015

• Subchronic haloperidol increases CB(1) receptor binding and G protein coupling in discrete regions of the basal ganglia.

  Journal of neuroscience research 20051015

• Mechanisms of action of mycophenolate mofetil in preventing acute and chronic allograft rejection.

  Transplantation 20051015

• RNA challenges for computational chemists.

  Biochemistry 20051011

• Structural and thermodynamic features of spiroiminodihydantoin damaged DNA duplexes.

  Biochemistry 20051011

• Design, synthesis, and preliminary pharmacological evaluation of a set of small molecules that directly activate gi proteins.

  Journal of medicinal chemistry 20051006

• Ribosome dysfunction is an early event in Alzheimer's disease.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20051005

• Metabotropic P2Y1 receptors inhibit P2X3 receptor-channels in rat dorsal root ganglion neurons.

  European journal of pharmacology 20051003

• 5-HT1A receptor-mediated G protein activation assessed by [35S]GTPgammaS binding in rat cerebral cortex.

  European journal of pharmacology 20051003

• Nucleoside transporter expression and function in cultured mouse astrocytes.

  Glia 20051001

• Differential effects of the 5-hydroxytryptamine (5-HT)1A receptor inverse agonists Rec 27/0224 and Rec 27/0074 on electrophysiological responses to 5-HT1A receptor activation in rat dorsal raphe nucleus and hippocampus in vitro.

  The Journal of pharmacology and experimental therapeutics 20051001

• Direct inhibition of substantia gelatinosa neurones in the rat spinal cord by activation of dopamine D2-like receptors.

  The Journal of physiology 20051001

• Chronic morphine up-regulates G alpha12 and cytoskeletal proteins in Chinese hamster ovary cells expressing the cloned mu opioid receptor.

  The Journal of pharmacology and experimental therapeutics 20051001

• Differential behavioral tolerance to the delta-opioid agonist SNC80 ([(+)-4-[(alphaR)-alpha-[(2S,5R)-2,5-dimethyl-4-(2-propenyl)-1-piperazinyl]-(3-methoxyphenyl)methyl]-N,N-diethylbenzamide) in Sprague-Dawley rats.

  The Journal of pharmacology and experimental therapeutics 20051001

• Regulation of ASAP1 by phospholipids is dependent on the interface between the PH and Arf GAP domains.

  Cellular signalling 20051001

• Activation and nuclear translocation of ERK1/2 by the formyl peptide receptor is regulated by G protein and is not dependent on beta-arrestin translocation or receptor endocytosis.

  Cellular signalling 20051001

• Synthetic oligonucleotides: AFM characterisation and electroanalytical studies.

  Bioelectrochemistry (Amsterdam, Netherlands) 20051001

• Biphenyl-indanones: allosteric potentiators of the metabotropic glutamate subtype 2 receptor.

  Bioorganic & medicinal chemistry letters 20051001

• Hypoxic-ischemic insult decreases glutamate uptake by hippocampal slices from neonatal rats: prevention by guanosine.

  Experimental neurology 20051001

• Synthesis and in vitro pharmacological studies of C(4) modified salvinorin A analogues.

  Bioorganic & medicinal chemistry letters 20051001

• Lysozyme binding to endocardial endothelium mediates myocardial depression by the nitric oxide guanosine 3',5' monophosphate pathway in sepsis.

  Journal of molecular and cellular cardiology 20051001

• Differential effects on [35S]GTPgammaS binding using muscarinic agonists and antagonists in the gerbil brain.

  Journal of chemical neuroanatomy 20051001

• Dynamics of SNARE assembly and disassembly during sperm acrosomal exocytosis.

  PLoS biology 20051001

• The antiviral drug ribavirin does not mimic the 7-methylguanosine moiety of the mRNA cap structure in vitro.

  RNA (New York, N.Y.) 20051001

• Diacylglycerol-activated Hmunc13 serves as an effector of the GTPase Rab34.

  Traffic (Copenhagen, Denmark) 20051001

• Atrial natriuretic peptide induces an acrosome reaction in giant panda spermatozoa and enhances their penetration of salt-stored porcine oocytes.

  Theriogenology 20051001

• Kinetics and crystal structure of human purine nucleoside phosphorylase in complex with 7-methyl-6-thio-guanosine.

  Archives of biochemistry and biophysics 20051001

• Characterization of porcine beta1- and beta2-adrenergic receptors in heart, skeletal muscle, and adipose tissue, and the identification of an atypical beta-adrenergic binding site.

  Journal of animal science 20051001

• Zinc-mediated inhibition of cyclic nucleotide phosphodiesterase activity and expression suppresses TNF-alpha and IL-1 beta production in monocytes by elevation of guanosine 3',5'-cyclic monophosphate.

  Journal of immunology (Baltimore, Md. : 1950) 20051001

• Selective phosphodiesterase 5 inhibition does not reduce propofol sedation requirements but affects speed of recovery and plasma cyclic guanosine 3',5'-monophosphate concentrations in healthy volunteers.

  Anesthesia and analgesia 20051001

• KKHA-761, a potent D3 receptor antagonist with high 5-HT1A receptor affinity, exhibits antipsychotic properties in animal models of schizophrenia.

  Pharmacology, biochemistry, and behavior 20051001

• Yersinia pseudotuberculosis spatially controls activation and misregulation of host cell Rac1.

  PLoS pathogens 20051001

• Hydrophilic statin suppresses vein graft intimal hyperplasia via endothelial cell-tropic Rho-kinase inhibition.

  Journal of vascular surgery 20051001

• Metabolism and disposition of the antiviral nucleoside analogue AM365 in the isolated perfused rat liver.

  Current drug metabolism 20051001

• Activation of natural killer-like YT-INDY cells by oligodeoxynucleotides and binding by homologous pattern recognition proteins.

  Scandinavian journal of immunology 20051001

• Kappa- and delta-opioid receptor functional activities are increased in the caudate putamen of cannabinoid CB1 receptor knockout mice.

  The European journal of neuroscience 20051001

• Antimicrobial drug resistance: 'Prediction is very difficult, especially about the future'.

  Emerging infectious diseases 20051001

• [(3)H]Alvimopan binding to the micro opioid receptor: comparative binding kinetics of opioid antagonists.

  European journal of pharmacology 20050927

• Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G.

  The Journal of biological chemistry 20050923

• Tautomers of one-electron-oxidized guanosine.

  Angewandte Chemie (International ed. in English) 20050919

• Giardia lamblia RNA cap guanine-N2 methyltransferase (Tgs2).

  The Journal of biological chemistry 20050916

• Structure-function studies on a synthetic guanosine receptor that simultaneously binds Watson-Crick and Hoogsteen sites.

  The Journal of organic chemistry 20050916

• Sildenafil improves alveolar growth and pulmonary hypertension in hyperoxia-induced lung injury.

  American journal of respiratory and critical care medicine 20050915

• Synthesis of long-chain amide analogs of the cannabinoid CB1 receptor antagonist N-(piperidinyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716) with unique binding selectivities and pharmacological activities.

  Bioorganic & medicinal chemistry 20050915

• Discovery of a potent and selective 5-ht5A receptor antagonist by high-throughput chemistry.

  Bioorganic & medicinal chemistry letters 20050915

• Transcriptional analysis of the cyclopropane fatty acid synthase gene of Lactococcus lactis MG1363 at low pH.

  FEMS microbiology letters 20050915

• Solid-state 87Rb NMR signatures for rubidium cations bound to a G-quadruplex.

  Chemical communications (Cambridge, England) 20050914

• Effects of statins on 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition beyond low-density lipoprotein cholesterol.

  The American journal of cardiology 20050905

• Interaction of calmodulin with the serotonin 5-hydroxytryptamine2A receptor. A putative regulator of G protein coupling and receptor phosphorylation by protein kinase C.

  The Journal of biological chemistry 20050902

• Crystal structure of M-Ras reveals a GTP-bound 'off' state conformation of Ras family small GTPases.

  The Journal of biological chemistry 20050902

• Kinetic analysis of steps in the repair of damaged DNA by human O6-alkylguanine-DNA alkyltransferase.

  The Journal of biological chemistry 20050902

• Structural evidence for a two-metal-ion mechanism of group I intron splicing.

  Science (New York, N.Y.) 20050902

• Novel antipsychotics activate recombinant human and native rat serotonin 5-HT1A receptors: affinity, efficacy and potential implications for treatment of schizophrenia.

  The international journal of neuropsychopharmacology 20050901

• Behavioral tolerance to lysergic acid diethylamide is associated with reduced serotonin-2A receptor signaling in rat cortex.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050901

• Guanine nucleotide exchange-independent activation of Gs protein by beta2-adrenoceptor.

  Molecular pharmacology 20050901

• Identification of four novel exon 5 splice variants of the mouse mu-opioid receptor gene: functional consequences of C-terminal splicing.

  Molecular pharmacology 20050901

• Functional complementation and the analysis of opioid receptor homodimerization.

  Molecular pharmacology 20050901

• The yicM (nepI) gene of Escherichia coli encodes a major facilitator superfamily protein involved in efflux of purine ribonucleosides.

  FEMS microbiology letters 20050901

• A new technique for the quantitative assessment of 8-oxoguanine in nuclear DNA as a marker of oxidative stress. Application to dystrophin-deficient DMD skeletal muscles.

  Histochemistry and cell biology 20050901

• Functional identification of catalytic metal ion binding sites within RNA.

  PLoS biology 20050901

• Redox metals and oxidative abnormalities in human prion diseases.

  Acta neuropathologica 20050901

• Isatoribine, an agonist of TLR7, reduces plasma virus concentration in chronic hepatitis C infection.

  Hepatology (Baltimore, Md.) 20050901

• Myocardial and coronary sinus purines as indicators of pig heart energy metabolism during reperfusion after extracorporeal circulation.

  Acta physiologica Scandinavica 20050901

• Hyperoxic ventilated premature baboons have increased p53, oxidant DNA damage and decreased VEGF expression.

  Pediatric research 20050901

• Effect of cardiopulmonary bypass and surgical intervention on the natriuretic hormone system in children.

  The Journal of thoracic and cardiovascular surgery 20050901

• Indirect activation of adenosine A1 receptors in cultured rat hippocampal neurons by volatile anaesthetics.

  European journal of anaesthesiology 20050901

• Nei deficient Escherichia coli are sensitive to chromate and accumulate the oxidized guanine lesion spiroiminodihydantoin.

  Chemical research in toxicology 20050901

• Mechanism of acrolein-induced vascular toxicity.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20050901

• Poly(ADP-ribose) polymerase-1 is a novel nuclear target for cholinergic receptor signaling in the hippocampus.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20050901

• Expression of inhibitory G proteins in adenomatous thyroid glands obtained from hyperthyroid cats.

  American journal of veterinary research 20050901

• [Identification of 5 constituents of the aqueous extract of Isatis indigotica by HPLC-MS2].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050901

• G-quartet-induced nanoparticle assembly.

  Journal of the American Chemical Society 20050824

• Regulation of human recombinant P2X3 receptors by ecto-protein kinase C.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050824

• Reduced kappa-opioid activity in a rat model of cholestasis.

  European journal of pharmacology 20050822

• Opioid receptor-like 1 (NOP) receptors in the rat dorsal raphe nucleus: evidence for localization on serotoninergic neurons and functional adaptation after 5,7-dihydroxytryptamine lesion.

  Journal of neuroscience research 20050815

• PHI-1 induced enhancement of myosin phosphorylation in chicken smooth muscle.

  FEBS letters 20050815

• WTH3, which encodes a small G protein, is differentially regulated in multidrug-resistant and sensitive MCF7 cells.

  Cancer research 20050815

• On-line hyphenation of quantum cascade laser and capillary electrophoresis.

  Journal of chromatography. A 20050812

• Oral human brain natriuretic peptide activates cyclic guanosine 3',5'-monophosphate and decreases mean arterial pressure.

  Circulation 20050809

• Distinct functional properties of native somatostatin receptor subtype 5 compared with subtype 2 in the regulation of ACTH release by corticotroph tumor cells.

  American journal of physiology. Endocrinology and metabolism 20050801

• Phenoxybenzamine and benextramine, but not 4-diphenylacetoxy-N-[2-chloroethyl]piperidine hydrochloride, display irreversible noncompetitive antagonism at G protein-coupled receptors.

  The Journal of pharmacology and experimental therapeutics 20050801

• Mu opioid receptor coupling to Gi/o proteins increases during postnatal development in rat brain.

  The Journal of pharmacology and experimental therapeutics 20050801

• The endocannabinoid noladin ether acts as a full agonist at human CB2 cannabinoid receptors.

  The Journal of pharmacology and experimental therapeutics 20050801

• Andrograpanin, a compound isolated from anti-inflammatory traditional Chinese medicine Andrographis paniculata, enhances chemokine SDF-1alpha-induced leukocytes chemotaxis.

  Journal of cellular biochemistry 20050801

• Effect of nitric oxide-cGMP-dependent protein kinase activation on advanced glycation end-product-induced proliferation in renal fibroblasts.

  Journal of the American Society of Nephrology : JASN 20050801

• Intriguing mass spectrometric behavior of guanosine under low energy collision-induced dissociation: H2O adduct formation and gas-phase reactions in the collision cell.

  Journal of the American Society for Mass Spectrometry 20050801

• Hydantoin derivative formation from oxidation of 7,8-dihydro-8-oxo-2'-deoxyguanosine (8-oxodG) and incorporation of 14C-labeled 8-oxodG into the DNA of human breast cancer cells.

  Bioorganic & medicinal chemistry letters 20050801

• Neutrophil dysfunction in guanosine 3',5'-cyclic monophosphate-dependent protein kinase I-deficient mice.

  Journal of immunology (Baltimore, Md. : 1950) 20050801

• Ribavirin is not a functional mimic of the 7-methyl guanosine mRNA cap.

  RNA (New York, N.Y.) 20050801

• Anesthetics inhibit membrane receptor coupling to the Gq/11 heterotrimeric G protein in airway smooth muscle.

  Anesthesiology 20050801

• Guanosine enhances glutamate transport capacity in brain cortical slices.

  Cellular and molecular neurobiology 20050801

• Structural-functional relationships between terminal deoxynucleotidyltransferase and 5'-triphosphates of nucleoside analogs.

  Biochemistry. Biokhimiia 20050801

• Agonistic properties of cannabidiol at 5-HT1a receptors.

  Neurochemical research 20050801

• Mycophenolic acid inhibits syncytium formation accompanied by reduction of gp120 expression.

  The Journal of antibiotics 20050801

• Structure of a class II TrmH tRNA-modifying enzyme from Aquifex aeolicus.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20050801

• The cytotoxic and anti-proliferative effects of 3-hydrogenkwadaphnin in K562 and jurkat cells is reduced by guanosine.

  Journal of biochemistry and molecular biology 20050731

• Precursors of chicken flavor. I. Determination of some flavor precursors in chicken muscle.

  Journal of agricultural and food chemistry 20050727

• Functional regulation of the opposing (p)ppGpp synthetase/hydrolase activities of RelMtb from Mycobacterium tuberculosis.

  Biochemistry 20050726

• Mechanisms of mu opioid receptor/G-protein desensitization in brain by chronic heroin administration.

  Life sciences 20050722

• Interleukin-1beta induces death in chondrocyte-like ATDC5 cells through mitochondrial dysfunction and energy depletion in a reactive nitrogen and oxygen species-dependent manner.

  The Biochemical journal 20050715

• Nitric oxide inhibits IFN-alpha production of human plasmacytoid dendritic cells partly via a guanosine 3',5'-cyclic monophosphate-dependent pathway.

  Journal of immunology (Baltimore, Md. : 1950) 20050715

• Cross-talk between adenosine and the oxatriazole derivative GEA 3175 in platelets.

  European journal of pharmacology 20050711

• In vitro profile of the antidepressant candidate OPC-14523 at rat and human 5-HT1A receptors.

  European journal of pharmacology 20050711

• The broadly selective human Na+/nucleoside cotransporter (hCNT3) exhibits novel cation-coupled nucleoside transport characteristics.

  The Journal of biological chemistry 20050708

• 2.0 A crystal structure of human ARL5-GDP3'P, a novel member of the small GTP-binding proteins.

  Biochemical and biophysical research communications 20050708

• Urinary nucleosides as biological markers for patients with colorectal cancer.

  World journal of gastroenterology 20050707

• Lack of G protein-coupled sigma receptors in rat brain membranes: receptor-mediated high-affinity GTPase activity and [35S]GTPgammaS binding studies.

  Journal of neural transmission (Vienna, Austria : 1996) 20050701

• Cadmium down-regulates human OGG1 through suppression of Sp1 activity.

  The Journal of biological chemistry 20050701

• G protein-dependent pharmacology of histamine H3 receptor ligands: evidence for heterogeneous active state receptor conformations.

  The Journal of pharmacology and experimental therapeutics 20050701

• A novel monothiol glutaredoxin (Grx4) from Escherichia coli can serve as a substrate for thioredoxin reductase.

  The Journal of biological chemistry 20050701

• Identification of WIN55212-3 as a competitive neutral antagonist of the human cannabinoid CB2 receptor.

  British journal of pharmacology 20050701

• Effects of an intense training on functional activity of 5-HT(1B) receptors in human peripheral blood lymphocytes.

  Neuroscience letters 20050701

• Binding properties of dipropyltryptamine at the human 5-HT1a receptor.

  Pharmacology 20050701

• Long-term depression in rat CA1-subicular synapses depends on the G-protein coupled mACh receptors.

  Neuroscience research 20050701

• Antihyperalgesic properties of the cannabinoid CT-3 in chronic neuropathic and inflammatory pain states in the rat.

  Pain 20050701

• Synthesis and biological studies of nociceptin derivatives containing the DTPA chelating group for further labeling with therapeutic radionuclides.

  Peptides 20050701

• Characterization of an ecto-ATPase activity in Cryptococcus neoformans.

  FEMS yeast research 20050701

• TYRA-2 (F01E11.5): a Caenorhabditis elegans tyramine receptor expressed in the MC and NSM pharyngeal neurons.

  Journal of neurochemistry 20050701

• NO-cGMP signaling molecules in cells of the rat molar dentin-pulp complex.

  Journal of dental research 20050701

• A single active-site region for a group II intron.

  Nature structural & molecular biology 20050701

• Structure of human PNP complexed with ligands.

  Acta crystallographica. Section D, Biological crystallography 20050701

• Effect of chronic gestational treatment with caffeine or theophylline on Group I metabotropic glutamate receptors in maternal and fetal brain.

  Journal of neurochemistry 20050701

• Guanine-specific oxidation of double-stranded DNA by Cr(VI) and ascorbic acid forms spiroiminodihydantoin and 8-oxo-2'-deoxyguanosine.

  Chemical research in toxicology 20050701

• Autoradiographic mapping of dopamine-D2/D3 receptor stimulated [35S]GTPgammaS binding in the human brain.

  The European journal of neuroscience 20050701

• Adenosine and purine nucleosides prevent the disruption of mitochondrial transmembrane potential by peroxynitrite in rat primary astrocytes.

  Archives of pharmacal research 20050701

• Pharmacokinetics and metabolism of acriflavine in rats following intravenous or intramuscular administration of AG60, a mixture of acriflavine and guanosine, a potential antitumour agent.

  Xenobiotica; the fate of foreign compounds in biological systems 20050701

• Reduction of ribonucleosides to 2'-deoxyribonucleosides.

  Current protocols in nucleic acid chemistry 20050701

• Distribution and abundance of metabotropic glutamate receptor subtype 2 in rat brain revealed by [3H]LY354740 binding in vitro and quantitative radioautography: correlation with the sites of synthesis, expression, and agonist stimulation of [35S]GTPgammas binding.

  The Journal of comparative neurology 20050620

• Clathrin-dependent and clathrin-independent retrieval of synaptic vesicles in retinal bipolar cells.

  Neuron 20050616

• Impaired base excision repair and accumulation of oxidative base lesions in CD4+ T cells of HIV-infected patients.

  Blood 20050615

• Expression of SphK1 impairs degranulation and motility of RBL-2H3 mast cells by desensitizing S1P receptors.

  Blood 20050615

• The synthesis of substituted bipiperidine amide compounds as CCR3 ligands: antagonists versus agonists.

  Bioorganic & medicinal chemistry letters 20050615

• Time-resolved resonance Raman observation of the 2-fluorenylnitrenium ion reaction with guanosine to form a C8 intermediate.

  Journal of the American Chemical Society 20050615

• Novel molecular drug carrier: encapsulation of oxaliplatin in cucurbit[7]uril and its effects on stability and reactivity of the drug.

  Organic & biomolecular chemistry 20050607

• Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron.

  The Journal of biological chemistry 20050603

• Abnormalities in uridine homeostatic regulation and pyrimidine nucleotide metabolism as a consequence of the deletion of the uridine phosphorylase gene.

  The Journal of biological chemistry 20050603

• Fancy bioisosteres: metallocene-derived G-protein-coupled receptor ligands with subnanomolar binding affinity and novel selectivity profiles.

  Journal of medicinal chemistry 20050602

• Locating counterions in guanosine quadruplexes: a contrast-variation neutron diffraction experiment in condensed hexagonal phase.

  The journal of physical chemistry. B 20050602

• Activation of BK channels in GH3 cells by a c-PLA2-dependent G-protein signaling pathway.

  Journal of neurophysiology 20050601

• Angiotensin II attenuates synaptic GABA release and excites paraventricular-rostral ventrolateral medulla output neurons.

  The Journal of pharmacology and experimental therapeutics 20050601

• In vivo characterization of 6beta-naltrexol, an opioid ligand with less inverse agonist activity compared with naltrexone and naloxone in opioid-dependent mice.

  The Journal of pharmacology and experimental therapeutics 20050601

• Pharmacological characterization of CXC chemokine receptor 3 ligands and a small molecule antagonist.

  The Journal of pharmacology and experimental therapeutics 20050601

• sigma Receptor activation blocks potassium channels and depresses neuroexcitability in rat intracardiac neurons.

  The Journal of pharmacology and experimental therapeutics 20050601

• An algorithm for identification of bacterial selenocysteine insertion sequence elements and selenoprotein genes.

  Bioinformatics (Oxford, England) 20050601

• Molecular dynamics simulation of clustered DNA damage sites containing 8-oxoguanine and abasic site.

  Journal of computational chemistry 20050601

• Effects of mycophenolic acid on endothelial cells.

  International immunopharmacology 20050601

• Purine nucleoside-mediated protection of chemical hypoxia-induced neuronal injuries involves p42/44 MAPK activation.

  Neurochemistry international 20050601

• A three-stemmed mRNA pseudoknot in the SARS coronavirus frameshift signal.

  PLoS biology 20050601

• Non-lesional vitiliginous melanocytes are not characterized by an increased proneness to nitric oxide-induced apoptosis.

  Experimental dermatology 20050601

• Effects of HIV Q151M-associated multi-drug resistance mutations on the activities of (-)-beta-D-1',3'-dioxolan guanine.

  Antiviral research 20050601

• Identification of the main oxidation products of 8-methoxy-2'-deoxyguanosine by singlet molecular oxygen.

  Free radical biology & medicine 20050601

• Photoinactivation of Escherichia coli using porphyrin derivatives with different number of cationic charges.

  FEMS immunology and medical microbiology 20050601

• Angiotensin II-evoked enhanced expression of RGS2 attenuates Gi-mediated adenylyl cyclase signaling in A10 cells.

  Cardiovascular research 20050601

• Determination of mercaptopurine and its four metabolites by large-volume sample stacking with polarity switching in capillary electrophoresis.

  Electrophoresis 20050601

• G protein-coupled galanin receptor distribution in the rat central nervous system.

  Neuropeptides 20050601

• Effects of central galanin administration on muscarinic cholinergic and galanin receptor G protein coupling.

  Neuropeptides 20050601

• Expression, purification, crystallization and preliminary X-ray analysis of a nucleoside kinase from the hyperthermophile Methanocaldococcus jannaschii.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20050601

• Responses of the ciliates Tetrahymena and Paramecium to external ATP and GTP.

  Purinergic signalling 20050601

• Guanosine stimulates neurite outgrowth in PC12 cells via activation of heme oxygenase and cyclic GMP.

  Purinergic signalling 20050601

• Structure-activity relationships of dinucleotides: Potent and selective agonists of P2Y receptors.

  Purinergic signalling 20050601

• Computational study of IAG-nucleoside hydrolase: determination of the preferred ground state conformation and the role of active site residues.

  Biochemistry 20050531

• Model for general acid-base catalysis by the hammerhead ribozyme: pH-activity relationships of G8 and G12 variants at the putative active site.

  Biochemistry 20050531

• Encephalitozoon cuniculi mRNA cap (guanine N-7) methyltransferase: methyl acceptor specificity, inhibition BY S-adenosylmethionine analogs, and structure-guided mutational analysis.

  The Journal of biological chemistry 20050527

• Insights into microtubule nucleation from the crystal structure of human gamma-tubulin.

  Nature 20050526

• Purification and characterization of RihC, a xanthosine-inosine-uridine-adenosine-preferring hydrolase from Salmonella enterica serovar Typhimurium.

  Biochimica et biophysica acta 20050525

• Identification and characterization of rel promoter element of Mycobacterium tuberculosis.

  Gene 20050523

• Identification of MrgX2 as a human G-protein-coupled receptor for proadrenomedullin N-terminal peptides.

  Biochemical and biophysical research communications 20050520

• Up-regulation of GABA(B) receptors by chronic administration of the GABA(B) receptor antagonist SCH 50,911.

  European journal of pharmacology 20050516

• Sequence-structure-function relationships of a tRNA (m7G46) methyltransferase studied by homology modeling and site-directed mutagenesis.

  Proteins 20050515

• Rapid activation of JNK and p38 by glucocorticoids in primary cultured hippocampal cells.

  Journal of neuroscience research 20050515

• Stimulation of neuropeptide Y-mediated calcium responses in human SMS-KAN neuroblastoma cells endogenously expressing Y2 receptors by co-expression of chimeric G proteins.

  Biochemical pharmacology 20050515

• A highly stable quadruply hydrogen-bonded heterocomplex useful for supramolecular polymer blends.

  Journal of the American Chemical Society 20050511

• Promiscuous catalysis by the tetrahymena group I ribozyme.

  Journal of the American Chemical Society 20050504

• 3-(2-Ethoxy-4-{4-[3-hydroxy-2-methyl-4-(3-methylbutanoyl)phenoxy]butoxy}phenyl)propanoic acid: a brain penetrant allosteric potentiator at the metabotropic glutamate receptor 2 (mGluR2).

  Bioorganic & medicinal chemistry letters 20050502

• Time-dependent changes in receptor/G-protein coupling in rat brain following chronic monoamine transporter blockade.

  The Journal of pharmacology and experimental therapeutics 20050501

• Characterization and comparison of recombinant human and rat TRPV1 receptors: effects of exo- and endocannabinoids.

  British journal of anaesthesia 20050501

• Orientational dynamics and dye-DNA interactions in a dye-labeled DNA aptamer.

  Biophysical journal 20050501

• Mechanisms of inverse agonist action at D2 dopamine receptors.

  British journal of pharmacology 20050501

• A combinatorial code for splicing silencing: UAGG and GGGG motifs.

  PLoS biology 20050501

• Binding and functional properties of the novel somatostatin analogue KE 108 at native mouse somatostatin receptors.

  Neuropharmacology 20050501

• Allosteric modulation of adenosine A1 receptor coupling to G-proteins in brain.

  Journal of neurochemistry 20050501

• Inhibitors of TLR-9 act on multiple cell subsets in mouse and man in vitro and prevent death in vivo from systemic inflammation.

  Journal of immunology (Baltimore, Md. : 1950) 20050501

• Stromal cell-derived factor-1alpha directly modulates voltage-dependent currents of the action potential in mammalian neuronal cells.

  Journal of neurochemistry 20050501

• Ras/ERK signalling in cannabinoid tolerance: from behaviour to cellular aspects.

  Journal of neurochemistry 20050501

• Single-molecule diffusion measurements of H-Ras at the plasma membrane of live cells reveal microdomain localization upon activation.

  Journal of cell science 20050501

• Vascular relaxation by the methanol extract of Sorbus cortex via NO-cGMP pathway.

  Biological & pharmaceutical bulletin 20050501

• Roles of Brucella abortus SpoT in morphological differentiation and intramacrophagic replication.

  Microbiology (Reading, England) 20050501

• Trazodone and its active metabolite m-chlorophenylpiperazine as partial agonists at 5-HT1A receptors assessed by [35S]GTPgammaS binding.

  Journal of psychopharmacology (Oxford, England) 20050501

• Detailed pharmacological characterization of 5-HT1A-receptor-mediated [35S]GTP gamma S binding in rat hippocampal membranes.

  Journal of pharmacological sciences 20050501

• ROCKs as therapeutic targets in cardiovascular diseases.

  Expert review of cardiovascular therapy 20050501

• The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites.

  Molecular cancer therapeutics 20050501

• Purine nucleosides stimulate Na/K ATPase, and prolong survival in hemorrhagic shock.

  The Journal of trauma 20050501

• Contractile properties of the cultured vascular smooth muscle cells: the crucial role played by RhoA in the regulation of contractility.

  Circulation research 20050429

• Spiroiminodihydantoin lesions derived from guanine oxidation: structures, energetics, and functional implications.

  Biochemistry 20050426

• Functional characterization of novel human and mouse equilibrative nucleoside transporters (hENT3 and mENT3) located in intracellular membranes.

  The Journal of biological chemistry 20050422

• Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene.

  Journal of molecular biology 20050422

• Group III metabotropic glutamate receptors and exocytosed protons inhibit L-type calcium currents in cones but not in rods.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050420

• 31P NMR and genetic analysis establish hinT as the only Escherchia coli purine nucleoside phosphoramidase and as essential for growth under high salt conditions.

  The Journal of biological chemistry 20050415

• LdARL-1 His-tagged recombinant protein: purification by immobilized metal affinity expanded bed adsorption.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050415

• Constitutively active G-protein-gated inwardly rectifying K+ channels in dendrites of hippocampal CA1 pyramidal neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050413

• Evidence for the involvement of cytosolic 5'-nucleotidase (cN-II) in the synthesis of guanine nucleotides from xanthosine.

  The Journal of biological chemistry 20050408

• Protein and RNA dynamics play key roles in determining the specific recognition of GU-rich polyadenylation regulatory elements by human Cstf-64 protein.

  Journal of molecular biology 20050408

• Selective modulation of neuronal nicotinic acetylcholine receptor channel subunits by Go-protein subunits.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050406

• Yeast-like mRNA capping apparatus in Giardia lamblia.

  The Journal of biological chemistry 20050401

• Inverse agonism and neutral antagonism at wild-type and constitutively active mutant delta opioid receptors.

  The Journal of pharmacology and experimental therapeutics 20050401

• Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: I. Potent and selective histamine H3 receptor antagonist with drug-like properties.

  The Journal of pharmacology and experimental therapeutics 20050401

• Visible light exposure induces VEGF gene expression through activation of retinoic acid receptor-alpha in retinoblastoma Y79 cells.

  American journal of physiology. Cell physiology 20050401

• A highly conserved glycine within linker I and the extreme C terminus of G protein alpha subunits interact cooperatively in switching G protein-coupled receptor-to-effector specificity.

  The Journal of pharmacology and experimental therapeutics 20050401

• Suramin disrupts receptor-G protein coupling by blocking association of G protein alpha and betagamma subunits.

  The Journal of pharmacology and experimental therapeutics 20050401

• Lipid rafts control signaling of type-1 cannabinoid receptors in neuronal cells. Implications for anandamide-induced apoptosis.

  The Journal of biological chemistry 20050401

• G protein-coupled receptor kinase regulates dopamine D3 receptor signaling by modulating the stability of a receptor-filamin-beta-arrestin complex. A case of autoreceptor regulation.

  The Journal of biological chemistry 20050401

• Effects of temperature on 2-[125I]-iodomelatonin binding to melatonin receptors in the neural retina of the frog Rana perezi.

  Journal of pineal research 20050401

• Functional recovery in aged and young rats after embolic stroke: treatment with a phosphodiesterase type 5 inhibitor.

  Stroke 20050401

• A cell-based cGMP assay useful for ultra-high-throughput screening and identification of modulators of the nitric oxide/cGMP pathway.

  Analytical biochemistry 20050401

• M opsin phosphorylation in intact mammalian retinas.

  Journal of neurochemistry 20050401

• Relationship between urinary cGMP excretion and serum total cholesterol levels in a general population.

  Atherosclerosis 20050401

• Identification and characterization of a functional, alternatively spliced Toll-like receptor 7 (TLR7) and genomic disruption of TLR8 in chickens.

  Immunology 20050401

• Various members of the Toll-like receptor family contribute to the innate immune response of human epidermal keratinocytes.

  Immunology 20050401

• Opioids inhibit purinergic nociceptors in the sensory neurons and fibres of rat via a G protein-dependent mechanism.

  Neuropharmacology 20050401

• Plasma L-arginine and metabolites of nitric oxide synthase in patients with left-to-right shunt after intracardiac repair.

  Chest 20050401

• A pentylenetetrazole-induced generalized seizure in early life enhances the efficacy of muscarinic receptor coupling to G-protein in hippocampus and neocortex of adult rat.

  The European journal of neuroscience 20050401

• G-protein coupled activation of potassium channels by endogenous neuropeptides in snail neurons.

  The European journal of neuroscience 20050401

• In vivo quinolinic acid increases synaptosomal glutamate release in rats: reversal by guanosine.

  Neurochemical research 20050401

• [The functional change in the 5-HT1A receptor induced by stress and the role of the 5-HT1A receptor in neuroprotection].

  Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20050401

• Arrangement of mRNA 3' of the A site codon on the human 80S ribosome.

  RNA biology 20050401

• Nitric oxide-dependent allosteric inhibitory role of a second nucleotide binding site in soluble guanylyl cyclase.

  The Journal of biological chemistry 20050325

• Electrochemical studies of guanosine in DMF and detection of its radical cation in a scanning electrochemical microscopy nanogap experiment.

  Journal of the American Chemical Society 20050323

• Photocrosslinking detects a compact, active structure of the hammerhead ribozyme.

  Biochemistry 20050322

• Translation initiation factor (eIF) 4B affects the rates of binding of the mRNA m7G cap analogue to wheat germ eIFiso4F and eIFiso4F.PABP.

  Biochemistry 20050322

• A mutant of eukaryotic protein synthesis initiation factor eIF4E(K119A) has an increased binding affinity for both m7G cap analogues and eIF4G peptides.

  Biochemistry 20050322

• Roles of conserved amino acid sequence motifs in the SpoU (TrmH) RNA methyltransferase family.

  The Journal of biological chemistry 20050318

• A mitotic septin scaffold required for Mammalian chromosome congression and segregation.

  Science (New York, N.Y.) 20050318

• Development of a mechanism-based assay for tissue transglutaminase--results of a high-throughput screen and discovery of inhibitors.

  Analytical biochemistry 20050315

• Composition and sequence-dependent binding of RNA to the nucleocapsid protein of Moloney murine leukemia virus.

  Biochemistry 20050315

• Major effect of pyrrolic N-benzylation in norbinaltorphimine, the selective kappa-opioid receptor antagonist.

  Journal of medicinal chemistry 20050310

• A 'locked-on,' constitutively active mutant of the adenosine A1 receptor.

  European journal of pharmacology 20050307

• Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor, vilazodone.

  European journal of pharmacology 20050307

• Periplakin interferes with G protein activation by the melanin-concentrating hormone receptor-1 by binding to the proximal segment of the receptor C-terminal tail.

  The Journal of biological chemistry 20050304

• Real-time detection of basal and stimulated G protein GTPase activity using fluorescent GTP analogues.

  The Journal of biological chemistry 20050304

• GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7.

  Molecular cell 20050304

• [(pF)Phe4,Arg14,Lys15]N/OFQ-NH2 (UFP-102), a highly potent and selective agonist of the nociceptin/orphanin FQ receptor.

  The Journal of pharmacology and experimental therapeutics 20050301

• Nonsteroidal anti-inflammatory drugs inhibit a Fyn-dependent pathway coupled to Rac and stress kinase activation in TCR signaling.

  Blood 20050301

• Residues Met89 and Ser160 in the human equilibrative nucleoside transporter 1 affect its affinity for adenosine, guanosine, S6-(4-nitrobenzyl)-mercaptopurine riboside, and dipyridamole.

  Molecular pharmacology 20050301

• Comparison of peptidic and nonpeptidic delta-opioid agonists on guanosine 5'-O-(3-[35S]thio)triphosphate ([35S]GTPgammaS) binding in brain slices from Sprague-Dawley rats.

  The Journal of pharmacology and experimental therapeutics 20050301

• Role of the C terminus in neuropeptide Y Y1 receptor desensitization and internalization.

  Molecular pharmacology 20050301

• Functional characterization of Galphao signaling through G protein-regulated inducer of neurite outgrowth 1.

  Molecular pharmacology 20050301

• Evidence for the functional expression and pharmacological characterization of adenine receptors in native cells and tissues.

  Molecular pharmacology 20050301

• Quantitative assessment of glucose transport in human skeletal muscle: dynamic positron emission tomography imaging of [O-methyl-11C]3-O-methyl-D-glucose.

  The Journal of clinical endocrinology and metabolism 20050301

• Identification and characterization of purine nucleoside transporters from Crithidia fasciculata.

  Molecular and biochemical parasitology 20050301

• Model platinum nucleobase and nucleoside complexes and antitumor activity: X-ray crystal structure of [PtIV(trans-1R,2R-diaminocyclohexane)trans-(acetate)2(9-ethylguanine)Cl]NO3.H2O.

  Journal of inorganic biochemistry 20050301

• Putting the brakes on cardiac hypertrophy: exploiting the NO-cGMP counter-regulatory system.

  Hypertension (Dallas, Tex. : 1979) 20050301

• Elevated levels of endocannabinoids and CB1 receptor-mediated G-protein signaling in the prefrontal cortex of alcoholic suicide victims.

  Biological psychiatry 20050301

• Vascular dysfunction in patients with chronic arsenosis can be reversed by reduction of arsenic exposure.

  Environmental health perspectives 20050301

• Transcriptional response of Rickettsia conorii exposed to temperature variation and stress starvation.

  Research in microbiology 20050301

• Role of progesterone signaling in the regulation of G-protein levels in female chronic constipation.

  Gastroenterology 20050301

• [Quantitative analysis of the nucleosides in Cordyceps sinensis with capillary zone electrophoresis].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050301

• Effects of dopamine, SKF-38393 and R(-)-NPA on ATP-activated currents in rat DRG neurons.

  Canadian journal of physiology and pharmacology 20050301

• [3H]LY334370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties.

  Naunyn-Schmiedeberg's archives of pharmacology 20050301

• P2X7 receptor stimulation of membrane internalization in a thyrocyte cell line.

  The Journal of membrane biology 20050301

• [Simultaneous determination of 7-methylguanosine and mitomycin C by capillary electrophoresis with amperometric detection].

  Se pu = Chinese journal of chromatography 20050301

• Methods for the detection of antioxidants which prevent age related diseases: a critical review with particular emphasis on human intervention studies.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20050301

• Role of cholesterol in ligand binding and G-protein coupling of serotonin1A receptors solubilized from bovine hippocampus.

  Biochemical and biophysical research communications 20050225

• Mechanisms mediating the biologic activity of synthetic proline, glycine, and hydroxyproline polypeptides in human neutrophils.

  Mediators of inflammation 20050224

• BU74, a complex oripavine derivative with potent kappa opioid receptor agonism and delayed opioid antagonism.

  European journal of pharmacology 20050221

• Oxidation of guanosine derivatives by a platinum(IV) complex: internal electron transfer through cyclization.

  Journal of the American Chemical Society 20050216

• Phosphodiester cleavage of guanylyl-(3',3')-(2'-amino-2'-deoxyuridine): rate acceleration by the 2'-amino function.

  Journal of the American Chemical Society 20050216

• Inhibition of phospholipase C-independent exocytotic responses in rat peritoneal mast cells by U73122.

  Regulatory peptides 20050215

• Neuronal nitric oxide modulates morphine antinociceptive tolerance by enhancing constitutive activity of the mu-opioid receptor.

  Biochemical pharmacology 20050215

• 1,2,4-Benzothiadiazine derivatives as alpha1 and 5-HT1A receptor ligands.

  Bioorganic & medicinal chemistry letters 20050215

• Stable isotope labeling-mass spectrometry analysis of methyl- and pyridyloxobutyl-guanine adducts of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in p53-derived DNA sequences.

  Biochemistry 20050215

• Identification of CD19 and CD20 peptides for induction of antigen-specific CTLs against B-cell malignancies.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050215

• Specificity and mechanism of RNA cap guanine-N2 methyltransferase (Tgs1).

  The Journal of biological chemistry 20050211

• Regulation of cap-dependent translation by eIF4E inhibitory proteins.

  Nature 20050203

• Chemo-enzymatic synthesis of 2'-O-methoxyethyl ribonucleosides using a phosphodiesterase from Serratia marcescens.

  Applied microbiology and biotechnology 20050201

• Endogenous regulator of g protein signaling proteins reduce {mu}-opioid receptor desensitization and down-regulation and adenylyl cyclase tolerance in C6 cells.

  The Journal of pharmacology and experimental therapeutics 20050201

• Anticataleptic properties of alpha2 adrenergic antagonists in the crossed leg position and bar tests: differential mediation by 5-HT1A receptor activation.

  Psychopharmacology 20050201

• Ca2+-independent hypoxic vasorelaxation in porcine coronary artery.

  The Journal of physiology 20050201

• Actin polymerization in the equatorial and postacrosomal regions of guinea pig spermatozoa during the acrosome reaction is regulated by G proteins.

  Molecular reproduction and development 20050201

• Dynamics and stability of GCAA tetraloops with 2-aminopurine and purine substitutions.

  Journal of biomolecular structure & dynamics 20050201

• Stimulation of G-proteins in human control and Alzheimer's disease brain by FAD mutants of APP(714-723): implication of oxidative mechanisms.

  Journal of neuroscience research 20050201

• Time-course of mitochondrial gene expressions in mice brains: implications for mitochondrial dysfunction, oxidative damage, and cytochrome c in aging.

  Journal of neurochemistry 20050201

• Stereoselective synthesis of 9-beta-d-arabianofuranosyl guanine and 2-amino-9-(beta-d-arabianofuranosyl)purine.

  Bioorganic & medicinal chemistry letters 20050201

• Triaryl bis-sulfones as a new class of cannabinoid CB2 receptor inhibitors: identification of a lead and initial SAR studies.

  Bioorganic & medicinal chemistry letters 20050201

• Nitric oxide-cyclic GMP contributes to abnormal activation of Na+-K+-ATPase in the aorta from rats with endotoxic shock.

  Shock (Augusta, Ga.) 20050201

• Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy.

  Nature medicine 20050201

• The role of G proteins in the activity and ethanol modulation of glycine-induced currents in rat neurons freshly isolated from the ventral tegmental area.

  Brain research 20050201

• Formation of conjugate adducts in the reactions of malonaldehyde-acetaldehyde and malonaldehyde-formaldehyde with guanosine.

  Chemical research in toxicology 20050201

• A competitive ELISA detecting 7-methylguanosine adduct induced by N-nitrosodimethylamine exposure.

  Human & experimental toxicology 20050201

• Succinate enhances the cyclic guanosine monophosphate-altered intestinal motility in the rat.

  The Journal of parasitology 20050201

• Genetic analysis and functional characterization of polymorphisms in the human concentrative nucleoside transporter, CNT2.

  Pharmacogenetics and genomics 20050201

• Nesiritide in cardiovascular anesthesia.

  Current opinion in anaesthesiology 20050201

• Copper and zinc inhibit Galphas function: a nucleotide-free state of Galphas induced by Cu2+ and Zn2+.

  The Journal of biological chemistry 20050128

• Atomic force microscopy study of the structural effects induced by echinomycin binding to DNA.

  Journal of molecular biology 20050128

• Crystal water dynamics of guanosine dihydrate: analysis of atomic displacement parameters, time profile of hydrogen-bonding probability, and translocation of water by MD simulation.

  The journal of physical chemistry. B 20050127

• Demonstration of an alternative mechanism for G-to-G cross-link formation.

  Journal of the American Chemical Society 20050126

• Antiviral function of APOBEC3G can be dissociated from cytidine deaminase activity.

  Current biology : CB 20050126

• Molecular recognition in a trans excision-splicing ribozyme: non-Watson-Crick base pairs at the 5' splice site and omegaG at the 3' splice site can play a role in determining the binding register of reaction substrates.

  Biochemistry 20050125

• Evaluation of the 17-kDa prenyl-binding protein as a regulatory protein for phototransduction in retinal photoreceptors.

  The Journal of biological chemistry 20050114

• Distinct molecular mechanisms for agonist peptide binding to types A and B cholecystokinin receptors demonstrated using fluorescence spectroscopy.

  The Journal of biological chemistry 20050114

• How flexible are fleximer nucleobases? A computational study.

  The journal of physical chemistry. A 20050113

• Nanocrystal-based bioelectronic coding of single nucleotide polymorphisms.

  Journal of the American Chemical Society 20050112

• Studies on the mechanism of the photo-induced DNA damage in the presence of acridizinium salts-involvement of singlet oxygen and an unusual source for hydroxyl radicals.

  Journal of the American Chemical Society 20050112

• Polo-like kinases in the nervous system.

  Oncogene 20050110

• Vesicle endocytosis requires dynamin-dependent GTP hydrolysis at a fast CNS synapse.

  Science (New York, N.Y.) 20050107

• [Cyclic GMP as a biomarker for cardiovascular disease and cancer].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20050106

• Measurement of serum pralidoxime methylsulfate (Contrathion) by high-performance liquid chromatography with electrochemical detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050105

• Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB(1) and CB(2) receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB(2) receptor agonists.

  Bioorganic & medicinal chemistry 20050103

• Tau modifiers as therapeutic targets for Alzheimer's disease.

  Biochimica et biophysica acta 20050103

• Identification and characterisation of a novel splice variant of the human CB1 receptor.

  FEBS letters 20050103

• Recognition of the oxidized lesions spiroiminodihydantoin and guanidinohydantoin in DNA by the mammalian base excision repair glycosylases NEIL1 and NEIL2.

  DNA repair 20050102

• Involvement of ryanodine receptors in muscarinic receptor-mediated membrane current oscillation in urinary bladder smooth muscle.

  American journal of physiology. Cell physiology 20050101

• Activation of an alpha2A-adrenoceptor-Galphao1 fusion protein dynamically regulates the palmitoylation status of the G protein but not of the receptor.

  The Biochemical journal 20050101

• Comparison of pharmacological activities of three distinct kappa ligands (Salvinorin A, TRK-820 and 3FLB) on kappa opioid receptors in vitro and their antipruritic and antinociceptive activities in vivo.

  The Journal of pharmacology and experimental therapeutics 20050101

• A Gbetagamma stimulated adenylyl cyclase is involved in Xenopus laevis oocyte maturation.

  Journal of cellular physiology 20050101

• Conserved residues F316 and G476 in the concentrative nucleoside transporter 1 (hCNT1) affect guanosine sensitivity and membrane expression, respectively.

  American journal of physiology. Cell physiology 20050101

• Reciprocal regulation of agonist and inverse agonist signaling efficacy upon short-term treatment of the human delta-opioid receptor with an inverse agonist.

  Molecular pharmacology 20050101

• Phosphatidylethanolamine enhances rhodopsin photoactivation and transducin binding in a solid supported lipid bilayer as determined using plasmon-waveguide resonance spectroscopy.

  Biophysical journal 20050101

• Increased D1 dopamine receptor signaling in levodopa-induced dyskinesia.

  Annals of neurology 20050101

• Nitric oxide-mediated regulation of connexin43 expression and gap junctional intercellular communication in mesangial cells.

  Journal of the American Society of Nephrology : JASN 20050101

• Effects of chronic administered guanosine on behavioral parameters and brain glutamate uptake in rats.

  Journal of neuroscience research 20050101

• Differential regulation of atrial natriuretic peptide- and adrenergic receptor-dependent lipolytic pathways in human adipose tissue.

  Metabolism: clinical and experimental 20050101

• Crystal structure of a phage Twort group I ribozyme-product complex.

  Nature structural & molecular biology 20050101

• Fast gas-phase hydrogen/deuterium exchange observed for a DNA G-quadruplex.

  Rapid communications in mass spectrometry : RCM 20050101

• Protective effect of adenosine and purine nucleos(t)ides against the death by hydrogen peroxide and glucose deprivation in rat primary astrocytes.

  Neuroscience research 20050101

• Autoradiographic characterisation of [35S]GTPgammaS binding stimulation mediated by 5-HT1B receptor in postmortem human brain.

  Neuropharmacology 20050101

• Effects of long-term biogenic amine transporter blockade on receptor/G-protein coupling in rat brain.

  Neuropharmacology 20050101

• Heart failure increases protein expression and enzymatic activity of heme oxygenase-1 in the lung.

  Cardiovascular research 20050101

• Taxonomic distribution and quantitative analysis of free purine and pyrimidine nucleosides in snake venoms.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050101

• The presence of a Leu-Gly-Asn repeat-enriched protein (LGN), a putative binding partner of transducin, in ROD photoreceptors.

  Investigative ophthalmology & visual science 20050101

• Oxidative nucleotide damage and superoxide dismutase expression in the brains of xeroderma pigmentosum group A and Cockayne syndrome.

  Brain & development 20050101

• Allosteric modulation of GABA(B) receptor function in human frontal cortex.

  Neurochemistry international 20050101

• The structure of a rigorously conserved RNA element within the SARS virus genome.

  PLoS biology 20050101

• Vasodilatation produced by orientin and its mechanism study.

  Biological & pharmaceutical bulletin 20050101

• [Natriuretic peptides: a new lipolytic pathway in human fat cells].

  Medecine sciences : M/S 20050101

• Mycophenolate mofetil modulates adhesion receptors of the beta1 integrin family on tumor cells: impact on tumor recurrence and malignancy.

  BMC cancer 20050101

• Acute impairment of contractile responses by 17beta-estradiol is cAMP and protein kinase G dependent in vascular smooth muscle cells of the porcine coronary arteries.

  British journal of pharmacology 20050101

• Terbutaline increases the cervical resistance of the pregnant rat in vitro.

  Naunyn-Schmiedeberg's archives of pharmacology 20050101

• Fish somatostatin sst3 receptor: comparison of radioligand and GTPgammaS binding, adenylate cyclase and phospholipase C activities reveals different agonist-dependent pharmacological signatures.

  Autonomic & autacoid pharmacology 20050101

• Deciphering structure and topology of conserved COG2042 orphan proteins.

  BMC structural biology 20050101

• Hypothesized deficiency of guanine-based purines may contribute to abnormalities of neurodevelopment, neuromodulation, and neurotransmission in Lesch-Nyhan syndrome.

  Clinical neuropharmacology 20050101

• Protein domains and architectural innovation in plant-associated Proteobacteria.

  BMC genomics 20050101

• Intracerebroventricular guanine-based purines protect against seizures induced by quinolinic acid in mice.

  Neurochemical research 20050101

• Mice have a transcribed L-threonine aldolase/GLY1 gene, but the human GLY1 gene is a non-processed pseudogene.

  BMC genomics 20050101

• Investigation of multiple binding sites on ribonuclease A using nano-electrospray ionization mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20050101

• Crystal structure of THEP1 from the hyperthermophile Aquifex aeolicus: a variation of the RecA fold.

  BMC structural biology 20050101

• Identification and characterization of Iporin as a novel interaction partner for rab1.

  BMC cell biology 20050101

• Enhanced striatal opioid receptor-mediated G-protein activation in L-DOPA-treated dyskinetic monkeys.

  Neuroscience 20050101

• Mechanisms of action of mycophenolate mofetil.

  Lupus 20050101

• [Phorbol 12-myristate 13-acetate inhibits apoptosis in erythroleukemia K562 cells induced by some nucleosides].

  Ontogenez 20050101

• 17Beta-estradiol modulates hMT1 melatonin receptor function.

  Neuroendocrinology 20050101

• The microbial selenoproteome of the Sargasso Sea.

  Genome biology 20050101

• S-nitrosothiols modulate G protein-coupled receptor signaling in a reversible and highly receptor-specific manner.

  BMC cell biology 20050101

• Pharmacological characterization of human kappa/mu opioid receptor chimeras that retain high affinity for dynorphin A.

  Current topics in medicinal chemistry 20050101

• Guanylic nucleotide starvation affects Saccharomyces cerevisiae mother-daughter separation and may be a signal for entry into quiescence.

  BMC cell biology 20050101

• Effects of mycophenolate mofetil on key pattern of coronary restenosis: a cascade of in vitro and ex vivo models.

  BMC cardiovascular disorders 20050101

• Nerve-induced release of nitric oxide from the rabbit corpus cavernosum is modulated by cyclic guanosine 3',5'-monophosphate.

  Neuroscience 20050101

• Identification and characterization of six new alternatively spliced variants of the human mu opioid receptor gene, Oprm.

  Neuroscience 20050101

• Expression and function of Toll-like receptors in chicken heterophils.

  Developmental and comparative immunology 20050101

• Inhibition of the cloned delayed rectifier K+ channels, Kv1.5 and Kv3.1, by riluzole.

  Neuroscience 20050101

• ATP-binding cassette (ABC) transporters in normal and pathological lung.

  Respiratory research 20050101

• Action of neuropeptide Y on nociceptive transmission in substantia gelatinosa of the adult rat spinal dorsal horn.

  Neuroscience 20050101

• Guanine-nucleotide exchange on ribosome-bound elongation factor G initiates the translocation of tRNAs.

  Journal of biology 20050101

• Cygnets: in vivo characterization of novel cGMP indicators and in vivo imaging of intracellular cGMP.

  Methods in molecular biology (Clifton, N.J.) 20050101

• High-throughput screening of phosphodiesterase activity in living cells.

  Methods in molecular biology (Clifton, N.J.) 20050101

• Assessment of phosphodiesterase isozyme contribution in cell and tissue extracts.

  Methods in molecular biology (Clifton, N.J.) 20050101

• Localization of cyclic guanosine 3',5'-monophosphate-hydrolyzing phosphodiesterase type 9 in rat brain by nonradioactive in situ hydridization.

  Methods in molecular biology (Clifton, N.J.) 20050101

• Cyclic guanosine 5'-monophosphate binding to regulatory GAF domains of photoreceptor phosphodiesterase.

  Methods in molecular biology (Clifton, N.J.) 20050101

• Radiolabeled ligand binding to the catalytic or allosteric sites of PDE5 and PDE11.

  Methods in molecular biology (Clifton, N.J.) 20050101

• Analysis of dimerization determinants of PDE6 catalytic subunits.

  Methods in molecular biology (Clifton, N.J.) 20050101

• Interactions between catalytic and inhibitory subunits of PDE6.

  Methods in molecular biology (Clifton, N.J.) 20050101

• Purification, reconstitution on lipid vesicles, and assays of PDE6 and its activator G protein, transducin.

  Methods in molecular biology (Clifton, N.J.) 20050101

• [Template location on the human ribosome: environment of the mRNA nucleotide adjacent to the A-site codon on the 3'-side].

  Bioorganicheskaia khimiia 20050101

• Photosensitive signal transduction induces membrane hyperpolarization in Paramecium bursaria.

  Photochemistry and photobiology 20050101

• A computational approach for identifying pathogenicity islands in prokaryotic genomes.

  BMC bioinformatics 20050101

• Macrophages and cytokines in the early defence against herpes simplex virus.

  Virology journal 20050101

• Ultra-low-dose naloxone suppresses opioid tolerance, dependence and associated changes in mu opioid receptor-G protein coupling and Gbetagamma signaling.

  Neuroscience 20050101

• Cell biology of diabetic kidney disease.

  Nephron. Experimental nephrology 20050101

• Retrons, msDNA, and the bacterial genome.

  Cytogenetic and genome research 20050101

• Long-term therapy of interferon-alpha induced pulmonary arterial hypertension with different PDE-5 inhibitors: a case report.

  Cardiovascular ultrasound 20050101

• Intracellularly truncated human alpha2B-adrenoceptors: stable and functional GPCRs for structural studies.

  Journal of receptor and signal transduction research 20050101

• Physicochemical modulation of agonist-induced [35s]GTPgammaS binding: implications for coexistence of multiple functional conformations of dopamine D1-like receptors.

  Journal of receptor and signal transduction research 20050101

• Calcium alginate microencapsulation of ovarian follicles impacts FSH delivery and follicle morphology.

  Reproductive biology and endocrinology : RB&E 20050101

• Identification of moaA3 gene in patient isolates of Mycobacterium tuberculosis in Kerala, which is absent in M. tuberculosis H37Rv and H37Ra.

  BMC infectious diseases 20050101

• Molecular mechanisms of autoimmunity triggered by microbial infection.

  Arthritis research & therapy 20050101

• Human Lsg1 defines a family of essential GTPases that correlates with the evolution of compartmentalization.

  BMC biology 20050101

• Alzheimer's disease related peptides affected cholinergic receptor mediated poly(ADP-ribose) polymerase activity in the hippocampus.

  Folia neuropathologica 20050101

• The diagnosis and therapy of brain tumours.

  Folia neuropathologica 20050101

• Kinetic properties of Cellulomonas sp. purine nucleoside phosphorylase with typical and non-typical substrates: implications for the reaction mechanism.

  Nucleosides, nucleotides & nucleic acids 20050101

• Synthesis and enzymatic characterization of methylene analogs of adenosine 5'-tetraphosphate (P4A).

  Nucleosides, nucleotides & nucleic acids 20050101

• Novel dinucleoside 5',5'-triphosphate cap analogues. Synthesis and affinity for murine translation factor eIF4E.

  Nucleosides, nucleotides & nucleic acids 20050101

• Synthesis of 5-aza-7-deazaguanine nucleoside derivatives as potential anti-flavivirus agents.

  Nucleosides, nucleotides & nucleic acids 20050101

• Design of highly efficient and selective transfer reaction of nitrosyl group to dc and d(M)C resulting in specific deamination.

  Nucleosides, nucleotides & nucleic acids 20050101

• Bis(tBuSATE) phosphotriester prodrugs of 8-azaguanosine and 6-methylpurine riboside; bis(pom) phosphotriester prodrugs of 2'-deoxy-4'-thioadenosine and its corresponding 9alpha anomer.

  Nucleosides, nucleotides & nucleic acids 20050101

• 7-deazapurin-2,6-diamine and 7-deazaguanine: synthesis and property of 7-substituted nucleosides and oligonucleotides.

  Nucleosides, nucleotides & nucleic acids 20050101

• A cautionary note on the use of the 31P NMR spectroscopy in stereochemical correlation analysis.

  Nucleosides, nucleotides & nucleic acids 20050101

• Synthesis study of 3'-alpha-fluoro-2',3'-dideoxyguanosine.

  Nucleosides, nucleotides & nucleic acids 20050101

• A new approach to oligonucleotide N3'-->P5' phosphoramidate building blocks.

  Nucleosides, nucleotides & nucleic acids 20050101

• Studies of the intermediary metabolism in cultured cells of the insect Spodoptera frugiperda using 13C- or 15N-labelled tracers.

  BMC biochemistry 20050101

• Formalin injection causes a coordinated spinal cord CO/NO-cGMP signaling system response.

  Molecular pain 20050101

• Characterization of 954 bovine full-CDS cDNA sequences.

  BMC genomics 20050101

• Phosphodiesterase 3 inhibition and cough in elderly asthmatics.

  Cough (London, England) 20050101

• A general method for nested RT-PCR amplification and sequencing the complete HCV genotype 1 open reading frame.

  Virology journal 20050101

• [Positioning of mRNA 3' of the a site bound codon on the human 80S ribosome].

  Molekuliarnaia biologiia 20050101

• Modulation of adenylyl cyclase activity in young and adult rat brain cortex. Identification of suramin as a direct inhibitor of adenylyl cyclase.

  Journal of cellular and molecular medicine 20050101

• [Specific arginine mediated RNA recognition].

  Postepy biochemii 20050101

• Microinjection as a tool to explore small GTPase function.

  Methods in enzymology 20050101

• In vitro assays of Arf1 interaction with GGA proteins.

  Methods in enzymology 20050101

• Assays and properties of arfaptin 2 binding to Rac1 and ADP-ribosylation factors (Arfs).

  Methods in enzymology 20050101

• A novel imidazole nucleoside containing a diaminodihydro-S-triazine as a substituent: inhibitory activity against the West Nile virus NTPase/helicase.

  Nucleosides, nucleotides & nucleic acids 20050101

• Opioid receptor binding characteristics and structure-activity studies of novel tetrapeptides in the TIPP (Tyr-Tic-Phe-Phe) series.

  Neuro-Signals 20050101

• Hypomodification of transfer RNA in cancer with respect to queuosine.

  RNA biology 20050101

• NMR spectroscopic analyses of functional nucleic acids-metal interaction and their solution structure analyses.

  Nucleic acids symposium series (2004) 20050101

• Synthesis of purin-2-yl carboxylate from O6-methylguanosine.

  Nucleic acids symposium series (2004) 20050101

• Structural change of tRNA (Gm18) methyltransferase by binding of methyl donor analogues.

  Nucleic acids symposium series (2004) 20050101

• Substitutions in the Reverse Transcriptase and Protease Genes of HIV-1 Subtype B in Untreated Individuals and Patients Treated With Antiretroviral Drugs.

  Journal of the International AIDS Society 20050101

• Galpha12 directly interacts with PP2A: evidence FOR Galpha12-stimulated PP2A phosphatase activity and dephosphorylation of microtubule-associated protein, tau.

  The Journal of biological chemistry 20041231

• The nuclear 16-kD protein methylation increases in the early period of liver regeneration in a hepatectomized rat.

  Experimental & molecular medicine 20041231

• A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists.

  Journal of medicinal chemistry 20041230

• Characterization of 5-hydroxy-8-oxo-7,8-dihydroguanosine in the photosensitized oxidation of 8-oxo-7,8-dihydroguanosine and its rearrangement to spiroiminodihydantoin.

  Journal of the American Chemical Society 20041229

• Improved detection limit for a direct determination of 8-hydroxy-2'-deoxyguanosine in untreated urine samples by capillary electrophoresis with optical detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225

• N-retinylidene-phosphatidylethanolamine is the preferred retinoid substrate for the photoreceptor-specific ABC transporter ABCA4 (ABCR).

  The Journal of biological chemistry 20041224

• Functional characterization of rhodopsin monomers and dimers in detergents.

  The Journal of biological chemistry 20041224

• Selective 226Ra2+ ionophores provided by self-assembly of guanosine and isoguanosine derivatives.

  Journal of the American Chemical Society 20041222

• Intra- and intercellular variations in the repair efficiency of O6-methylguanine, and their contribution to kinetic complexity.

  Mutation research 20041221

• Induction of A:T to G:C transition mutations by 5-(2-chloroethyl)-2'-deoxyuridine (CEDU), an antiviral pyrimidine nucleoside analogue, in the bone marrow of Muta Mouse.

  Mutation research 20041221

• Using diffusion NMR to characterize guanosine self-association: insights into structure and mechanism.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20041217

• Differentiation of human prostate cancer PC-3 cells induced by inhibitors of inosine 5'-monophosphate dehydrogenase.

  Cancer research 20041215

• Monitoring HSVtk suicide gene therapy: the role of [(18)F]FHPG membrane transport.

  British journal of cancer 20041213

• ADP-ribosylation factor 1-independent protein sorting and export from the trans-Golgi network.

  The Journal of biological chemistry 20041210

• Promoting vibrations in human purine nucleoside phosphorylase. A molecular dynamics and hybrid quantum mechanical/molecular mechanical study.

  Journal of the American Chemical Society 20041208

• A cyclic peptide mimicking the third intracellular loop of the V2 vasopressin receptor inhibits signaling through its interaction with receptor dimer and G protein.

  The Journal of biological chemistry 20041203

• Uncoupling of GPCR and RhoA-induced Ca2+-sensitization of chicken amnion smooth muscle lacking CPI-17.

  FEBS letters 20041203

• Orexin (hypocretin) effects on constitutively active inward rectifier K+ channels in cultured nucleus basalis neurons.

  Journal of neurophysiology 20041201

• Signaling and ligand binding by recombinant neuromedin U receptors: evidence for dual coupling to Galphaq/11 and Galphai and an irreversible ligand-receptor interaction.

  Molecular pharmacology 20041201

• Mechanisms of agonist action at D2 dopamine receptors.

  Molecular pharmacology 20041201

• A molecular code for splicing silencing: configurations of guanosine-rich motifs.

  Biochemical Society transactions 20041201

• Synthesis and biological evaluation of 5R- and 5S-methyl substituted D- and L-configuration 1,3-dioxolane nucleoside analogs.

  Bioorganic & medicinal chemistry 20041201

• Widespread A-to-I RNA editing of Alu-containing mRNAs in the human transcriptome.

  PLoS biology 20041201

• A survey of RNA editing in human brain.

  Genome research 20041201

• JNJ16259685, a highly potent, selective and systemically active mGlu1 receptor antagonist.

  Neuropharmacology 20041201

• Inhibition of phosphodiesterase 2 increases neuronal cGMP, synaptic plasticity and memory performance.

  Neuropharmacology 20041201

• Regulation of A2B adenosine receptor functioning by tumour necrosis factor a in human astroglial cells.

  Journal of neurochemistry 20041201

• Proteasome inhibition increases DNA and RNA oxidation in astrocyte and neuron cultures.

  Journal of neurochemistry 20041201

• Montmorillonite, oligonucleotides, RNA and origin of life.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20041201

• A new synthetic approach of N-(4-amino-2-methylquinolin-6-yl)-2-(4-ethylphenoxymethyl)benzamide (JTC-801) and its analogues and their pharmacological evaluation as nociceptin receptor (NOP) antagonists.

  European journal of medicinal chemistry 20041201

• Mycophenolic acid inhibits platelet-derived growth factor-induced reactive oxygen species and mitogen-activated protein kinase activation in rat vascular smooth muscle cells.

  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20041201

• Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects. 1983.

  British journal of clinical pharmacology 20041201

• A calcium channel blocker, benidipine, improves cell membrane fluidity in human subjects via a nitric oxide-dependent mechanism. An electron paramagnetic resonance investigation.

  American journal of hypertension 20041201

• Chromatographic separation of nucleosides using a cross-linked xylose isomerase crystal stationary phase.

  Journal of separation science 20041201

• P2Y receptors and pain transmission.

  Purinergic signalling 20041201

• DNA . RNA heteroduplex containing 8-oxo-7,8-dihydroguanosine: base pairing, structures, and thermodynamic stability.

  Journal of biochemistry and molecular biology 20041130

• Identification and separation of PCR products based on their GC content by denaturing high-performance liquid chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041125

• Poly-guanosine strings improve cellular uptake and stimulatory activity of phosphodiester CpG oligonucleotides in human leukocytes.

  Vaccine 20041125

• Irsogladine, an anti-ulcer drug, suppresses superoxide production by inhibiting phosphodiesterase type 4 in human neutrophils.

  Life sciences 20041119

• Pontine and basal forebrain cholinergic interaction: implications for sleep and breathing.

  Respiratory physiology & neurobiology 20041115

• Electrochemical sensing of the behaviour of oligonucleotide lipoplexes at charged interfaces.

  Biosensors & bioelectronics 20041115

• RhoA activates purified phospholipase C-epsilon by a guanine nucleotide-dependent mechanism.

  The Journal of biological chemistry 20041112

• Structural mimicry in class A G protein-coupled receptor rotamer toggle switches: the importance of the F3.36(201)/W6.48(357) interaction in cannabinoid CB1 receptor activation.

  The Journal of biological chemistry 20041112

• A novel Galphaq/11-selective inhibitor.

  The Journal of biological chemistry 20041112

• Caveolae localize protein kinase A signaling to arterial ATP-sensitive potassium channels.

  Circulation research 20041112

• Folding thermodynamics and kinetics of YNMG RNA hairpins: specific incorporation of 8-bromoguanosine leads to stabilization by enhancement of the folding rate.

  Biochemistry 20041109

• Human ribosomal protein S3 interacts with DNA base excision repair proteins hAPE/Ref-1 and hOGG1.

  Biochemistry 20041109

• The RGS14 GoLoco domain discriminates among Galphai isoforms.

  The Journal of biological chemistry 20041105

• Analysis of platinum adducts with DNA nucleotides and nucleosides by capillary electrophoresis coupled to ESI-MS: indications of guanosine 5'-monophosphate O6-N7 chelation.

  Chembiochem : a European journal of chemical biology 20041105

• Structure of the Tetrahymena ribozyme: base triple sandwich and metal ion at the active site.

  Molecular cell 20041105

• Simultaneous determination of six main nucleosides and bases in natural and cultured Cordyceps by capillary electrophoresis.

  Journal of chromatography. A 20041105

• Mu and delta opioid-stimulated [35S]GTP gamma S binding in brain and spinal cord of polyarthritic rats.

  European journal of pharmacology 20041103

• Transcription activities at 8-oxoG lesions in DNA.

  DNA repair 20041102

• Layer variations of long-term depression in rat visual cortex.

  Journal of neurophysiology 20041101

• Oxidative DNA damage and DNA repair enzyme expression are inversely related in murine models of fatty liver disease.

  American journal of physiology. Gastrointestinal and liver physiology 20041101

• Genomic organization of mouse orexin receptors: characterization of two novel tissue-specific splice variants.

  Molecular endocrinology (Baltimore, Md.) 20041101

• Dopamine recruits D1A receptors to Na-K-ATPase-rich caveolar plasma membranes in rat renal proximal tubules.

  American journal of physiology. Renal physiology 20041101

• Gialpha3 protein-coupled dopamine D3 receptor-mediated inhibition of renal NHE3 activity in SHR proximal tubular cells is a PLC-PKC-mediated event.

  American journal of physiology. Renal physiology 20041101

• The serine repeat antigen (SERA) gene family phylogeny in Plasmodium: the impact of GC content and reconciliation of gene and species trees.

  Molecular biology and evolution 20041101

• Cyclic GMP transporters.

  Neurochemistry international 20041101

• Metabolic regulation of ATP breakdown and of adenosine production in rat brain extracts.

  The international journal of biochemistry & cell biology 20041101

• TRPC5 activation kinetics are modulated by the scaffolding protein ezrin/radixin/moesin-binding phosphoprotein-50 (EBP50).

  Journal of cellular physiology 20041101

• Anabolism of amdoxovir: phosphorylation of dioxolane guanosine and its 5'-phosphates by mammalian phosphotransferases.

  Biochemical pharmacology 20041101

• G protein activation and cyclic AMP modulation by naloxone benzoylhydrazone in distinct layers of rat olfactory bulb.

  British journal of pharmacology 20041101

• Multiple actions of extracellular ATP and adenosine on calcium currents mediated by various purinoceptors in neurons of nucleus tractus solitarius.

  Neuroscience research 20041101

• Hetero-oligomers of alpha2A-adrenergic and mu-opioid receptors do not lead to transactivation of G-proteins or altered endocytosis profiles.

  Biochemical Society transactions 20041101

• Homocysteine activates NADH/NADPH oxidase through ceramide-stimulated Rac GTPase activity in rat mesangial cells.

  Kidney international 20041101

• His452Tyr polymorphism in the human 5-HT2A receptor destabilizes the signaling conformation.

  Molecular pharmacology 20041101

• Conservation of capa peptide-induced nitric oxide signalling in Diptera.

  The Journal of experimental biology 20041101

• Alternative substrates for wild-type and L109A E. coli CTP synthases: kinetic evidence for a constricted ammonia tunnel.

  European journal of biochemistry 20041101

• Uroguanylin and guanylin peptides: pharmacology and experimental therapeutics.

  Pharmacology & therapeutics 20041101

• Identification of three new alternatively spliced variants of the rat mu opioid receptor gene: dissociation of affinity and efficacy.

  Journal of neurochemistry 20041101

• Potentiation of 5-HT3 receptor function by the activation of coexistent 5-HT2 receptors in trigeminal ganglion neurons of rats.

  Neuropharmacology 20041101

• The influence of G protein subtype on agonist action at D2 dopamine receptors.

  Neuropharmacology 20041101

• Mass spectrometric identification of 4-hydroxy-2,5-dioxo-imidazolidine-4-carboxylic acid during oxidation of 8-oxoguanosine by peroxynitrite and KHSO5/CoCl2.

  Chemical research in toxicology 20041101

• Spiroiminodihydantoin and guanidinohydantoin are the dominant products of 8-oxoguanosine oxidation at low fluxes of peroxynitrite: mechanistic studies with 18O.

  Chemical research in toxicology 20041101

• Plasminogen activator inhibitor-1 plasma level increases with age in subjects with the 4G allele at position -675 in the promoter region.

  Thrombosis and haemostasis 20041101

• Allelic isoforms of the H+/nucleoside co-transporter (CaCNT) from Candida albicans reveal separate high- and low-affinity transport systems for nucleosides.

  Yeast (Chichester, England) 20041101

• Distinction of water-soluble constituents between natural and cultured Cordyceps by capillary electrophoresis.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20041101

• An enzyme-linked immunosorbent assay for the rapid quantification of intracellular and extracellular guanosine 3',5'-cyclic monophosphate in cultured glial cells.

  Neurochemical research 20041101

• A novel combination of opiates and endothelin antagonists to manage pain without any tolerance development.

  Journal of cardiovascular pharmacology 20041101

• Role of endothelin in neonatal morphine tolerance.

  Journal of cardiovascular pharmacology 20041101

• TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor.

  The Journal of biological chemistry 20041029

• Solid-state 23Na NMR determination of the number and coordination of sodium cations bound to Oxytricha nova telomere repeat d(G4T4G4).

  Biochemical and biophysical research communications 20041029

• Thermodynamics of mRNA 5' cap binding by eukaryotic translation initiation factor eIF4E.

  Biochemistry 20041026

• Selectivity, cooperativity, and reciprocity in the interactions between the delta-opioid receptor, its ligands, and G-proteins.

  The Journal of biological chemistry 20041022

• Cephamycin C production is regulated by relA and rsh genes in Streptomyces clavuligerus ATCC27064.

  Journal of biotechnology 20041019

• Pharmacological and functional biochemical properties of D-Ala2-D-Nle5-enkephalin-Arg-Phe.

  Regulatory peptides 20041015

• MicroRNA genes are transcribed by RNA polymerase II.

  The EMBO journal 20041013

• Use of chelating ligands to tune the reactive site of half-sandwich ruthenium(II)-arene anticancer complexes.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20041011

• Acid-base properties of xanthosine 5'-monophosphate (XMP) and of some related nucleobase derivatives in aqueous solution: micro acidity constant evaluations of the (N1)H versus the (N3)H deprotonation ambiguity.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20041011

• Identification of CC chemokine receptor 7 residues important for receptor activation.

  The Journal of biological chemistry 20041008

• Guanosine selectively inhibits locomotor stimulation induced by the NMDA antagonist dizocilpine.

  Behavioural brain research 20041005

• 8-Bromo-cAMP decreases the Ca2+ sensitivity of airway smooth muscle contraction through a mechanism distinct from inhibition of Rho-kinase.

  American journal of physiology. Lung cellular and molecular physiology 20041001

• Downregulation of cGMP-dependent protein kinase-1 activity in the corpus cavernosum smooth muscle of diabetic rabbits.

  American journal of physiology. Regulatory, integrative and comparative physiology 20041001

• Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells.

  Blood 20041001

• Characterization of three novel members of the Arabidopsis thaliana equilibrative nucleoside transporter (ENT) family.

  The Biochemical journal 20041001

• Cocaine alters GABA(B)-mediated G-protein activation in the ventral tegmental area of female rats: modulation by estrogen.

  Synapse (New York, N.Y.) 20041001

• Mycophenolates in transplantation.

  Clinical transplantation 20041001

• Spectroscopic characterization of fluorescein- and tetramethylrhodamine-labeled oligonucleotides and their complexes with a DNA template.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20041001

• Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease.

  Neurobiology of disease 20041001

• Benzimidazole derivatives. Part 5: design and synthesis of new benzimidazole-arylpiperazine derivatives acting as mixed 5-HT1A/5-HT3 ligands.

  Bioorganic & medicinal chemistry 20041001

• Evidence for biological effects of exogenous LPA on rat primary afferent and spinal cord neurons.

  Brain research 20041001

• Stimulation of cyclic GMP efflux in human melanocytes by hypergravity generated by centrifugal acceleration.

  Pigment cell research 20041001

• Overexpression and functional characterisation of the human melanocortin 4 receptor in Sf9 cells.

  Protein expression and purification 20041001

• The influence of DNA stiffness upon nucleosome formation.

  Journal of structural biology 20041001

• Synergistic effects of ANP and sildenafil on cGMP levels and amelioration of acute hypoxic pulmonary hypertension.

  Experimental biology and medicine (Maywood, N.J.) 20041001

• Nitric oxide-sensitive soluble guanylyl cyclase activity is preserved in internal mammary artery of type 2 diabetic patients.

  Diabetes 20041001

• Identification and characterization of a novel gene of grouper iridovirus encoding a purine nucleoside phosphorylase.

  The Journal of general virology 20041001

• Mycophenolic acid inhibits avian reovirus replication.

  Antiviral research 20041001

• Insulin activates vascular endothelial growth factor in vascular smooth muscle cells: influence of nitric oxide and of insulin resistance.

  European journal of clinical investigation 20041001

• Determination of glycated nucleobases in human urine by a new monoclonal antibody specific for N2-carboxyethyl-2'-deoxyguanosine.

  Chemical research in toxicology 20041001

• Dynamin- and clathrin-dependent endocytic pathway in unicellular eukaryote Paramecium.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20041001

• Purine nucleoside phosphorylase activity in rat cerebrospinal fluid.

  Neurochemical research 20041001

• 5-(1-Substituted) alkyl pyrimidine nucleosides as antiviral (herpes) agents.

  Current medicinal chemistry 20041001

• Synthesis and polymerase incorporation of 5'-amino-2',5'-dideoxy-5'-N-triphosphate nucleotides.

  Current protocols in nucleic acid chemistry 20041001

• Structural basis for packaging the dimeric genome of Moloney murine leukaemia virus.

  Nature 20040930

• Biochemical brain markers and purinergic parameters in rat CSF after seizure induced by pentylenetetrazol.

  Brain research bulletin 20040930

• Heterooligomeric phosphoribosyl diphosphate synthase of Saccharomyces cerevisiae: combinatorial expression of the five PRS genes in Escherichia coli.

  The Journal of biological chemistry 20040924

• Enhancing Hoogsteen interactions: a pyrrole-containing purine nucleoside that competes with guanosine self-assembly.

  Journal of the American Chemical Society 20040922

• Synthesis, physicochemical and biochemical studies of 1',2'-oxetane constrained adenosine and guanosine modified oligonucleotides, and their comparison with those of the corresponding cytidine and thymidine analogues.

  Journal of the American Chemical Society 20040922

• In vitro characterization of AR-A000002, a novel 5-hydroxytryptamine(1B) autoreceptor antagonist.

  European journal of pharmacology 20040919

• Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi alpha-subunits.

  European journal of pharmacology 20040919

• Characterization of the complex morphinan derivative BU72 as a high efficacy, long-lasting mu-opioid receptor agonist.

  European journal of pharmacology 20040919

• Perturbing the linker regions of the alpha-subunit of transducin: a new class of constitutively active GTP-binding proteins.

  The Journal of biological chemistry 20040917

• Mitochondrial fusion intermediates revealed in vitro.

  Science (New York, N.Y.) 20040917

• Structure of Mycobacterium tuberculosis FtsZ reveals unexpected, G protein-like conformational switches.

  Journal of molecular biology 20040917

• A transition state analogue for an RNA-editing reaction.

  Journal of the American Chemical Society 20040915

• G-quartet oligonucleotides: a new class of signal transducer and activator of transcription 3 inhibitors that suppresses growth of prostate and breast tumors through induction of apoptosis.

  Cancer research 20040915

• Adenosine A1 receptor-dependent G-protein activity in the rat brain during prolonged wakefulness.

  Neuroreport 20040915

• Stimulation of DNA glycosylase activity of OGG1 by NEIL1: functional collaboration between two human DNA glycosylases.

  Biochemistry 20040914

• Regulation of the coupling to different G proteins of rat corticotropin-releasing factor receptor type 1 in human embryonic kidney 293 cells.

  The Journal of biological chemistry 20040910

• Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.

  Nature 20040909

• Hydrolytic reactions of guanosyl-(3',3')-uridine and guanosyl-(3',3')-(2',5'-di-O-methyluridine).

  Journal of the American Chemical Society 20040908

• Dysregulation of apoptosis by benzene metabolites and their relationships with carcinogenesis.

  Biochimica et biophysica acta 20040906

• Ectopically expressed gamma-aminobutyric acid receptor B is functionally down-regulated in isolated lipid raft-enriched membranes.

  Biochemical and biophysical research communications 20040903

• Chronic antidepressant treatment causes a selective reduction of mu-opioid receptor binding and functional coupling to G Proteins in the amygdala of fawn-hooded rats.

  The Journal of pharmacology and experimental therapeutics 20040901

• Solution structure of an RNA stem-loop derived from the 3' conserved region of eel LINE UnaL2.

  RNA (New York, N.Y.) 20040901

• Pharmacological and behavioral properties of A-349821, a selective and potent human histamine H3 receptor antagonist.

  Biochemical pharmacology 20040901

• Electrochemical study of quercetin-DNA interactions: part I. Analysis in incubated solutions.

  Bioelectrochemistry (Amsterdam, Netherlands) 20040901

• Electrochemical study of quercetin-DNA interactions: part II. In situ sensing with DNA biosensors.

  Bioelectrochemistry (Amsterdam, Netherlands) 20040901

• Targeted disruption of PSD-93 gene reduces platelet-activating factor-induced neurotoxicity in cultured cortical neurons.

  Experimental neurology 20040901

• Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase.

  The EMBO journal 20040901

• Structure-activity studies on high affinity NOP-active hexapeptides.

  The journal of peptide research : official journal of the American Peptide Society 20040901

• Single-base oligodeoxyguanosine-binding proteins on nonspecific cytotoxic cells: identification of a new class of pattern-recognition receptors.

  Scandinavian journal of immunology 20040901

• Mesenchymal stem cells inhibit the expression of CD25 (interleukin-2 receptor) and CD38 on phytohaemagglutinin-activated lymphocytes.

  Scandinavian journal of immunology 20040901

• Functional role of a C-terminal Gbetagamma-binding domain of Ca(v)2.2 channels.

  Molecular pharmacology 20040901

• C-type natriuretic peptide as a podocyte hormone and modulation of its cGMP production by glucose and mechanical stress.

  Kidney international 20040901

• Protein kinase B, P34cdc2 kinase, and p21 ras GTP-binding in kidneys of aging rats.

  Experimental biology and medicine (Maywood, N.J.) 20040901

• Modulation of extracellular signal-regulated kinase (ERK) activity by acute and chronic opioid treatment in neuronal and glial cell lines.

  Journal of neurochemistry 20040901

• Cytokine-induced nitric oxide inhibits mitochondrial energy production and induces myocardial dysfunction in endotoxin-treated rat hearts.

  Journal of molecular and cellular cardiology 20040901

• RGS 2 expression is regulated by TSH and inhibits TSH receptor signaling.

  European journal of endocrinology 20040901

• The binding selectivity of ADAR2's dsRBMs contributes to RNA-editing selectivity.

  Chemistry & biology 20040901

• Effect of lead ions on rat erythrocyte purine content.

  Biological trace element research 20040901

• [Determination of four nucleosides in Banlangen injections using capillary zone electrophoresis].

  Se pu = Chinese journal of chromatography 20040901

• Efficiency of repair of an abasic site within DNA clustered damage sites by mammalian cell nuclear extracts.

  Biochemistry 20040831

• N2-methylation of guanosine at position 10 in tRNA is catalyzed by a THUMP domain-containing, S-adenosylmethionine-dependent methyltransferase, conserved in Archaea and Eukaryota.

  The Journal of biological chemistry 20040827

• Alpha1B-adrenoceptor signaling and cell motility: GTPase function of Gh/transglutaminase 2 inhibits cell migration through interaction with cytoplasmic tail of integrin alpha subunits.

  The Journal of biological chemistry 20040827

• A new approach to natural products discovery exemplified by the identification of sulfated nucleosides in spider venom.

  Journal of the American Chemical Society 20040825

• Cell-specific manipulation of second messengers; a toolbox for integrative physiology in Drosophila.

  Current biology : CB 20040824

• A structural basis for the inhibition of the NS5 dengue virus mRNA 2'-O-methyltransferase domain by ribavirin 5'-triphosphate.

  The Journal of biological chemistry 20040820

• Elevated expression level of 60-kDa subunit of tRNA-guanine transglycosylase in colon cancer.

  Cancer letters 20040820

• Quinolinic acid promotes seizures and decreases glutamate uptake in young rats: reversal by orally administered guanosine.

  Brain research 20040820

• 5-Cyanoimino-4-oxomethylene-4,5-dihydroimidazole and 5-cyanoamino-4-imidazolecarboxylic acid intermediates in nitrosative guanosine deamination: evidence from 18O-labeling experiments.

  Journal of the American Chemical Society 20040818

• Altered permeability and modulatory character of connexin channels during mammary gland development.

  Experimental cell research 20040815

• Characterization of MOCS1A, an oxygen-sensitive iron-sulfur protein involved in human molybdenum cofactor biosynthesis.

  The Journal of biological chemistry 20040813

• Mepyramine, a histamine H1 receptor inverse agonist, binds preferentially to a G protein-coupled form of the receptor and sequesters G protein.

  The Journal of biological chemistry 20040813

• Tricyclic alkylamides as melatonin receptor ligands with antagonist or inverse agonist activity.

  Journal of medicinal chemistry 20040812

• Spermine participates in oxidative damage of guanosine and 8-oxoguanosine leading to deoxyribosylurea formation.

  Journal of the American Chemical Society 20040811

• A novel series of 2-pyridyl-containing compounds as lysophosphatidic acid receptor antagonists: development of a nonhydrolyzable LPA3 receptor-selective antagonist.

  Bioorganic & medicinal chemistry letters 20040802

• Characterisation of GEA 3175 on human platelets; comparison with S-nitroso-N-acetyl-D,L-penicillamine.

  European journal of pharmacology 20040802

• DiPOA ([8-(3,3-diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl]-acetic acid), a novel, systemically available, and peripherally restricted mu opioid agonist with antihyperalgesic activity: I. In vitro pharmacological characterization and pharmacokinetic properties.

  The Journal of pharmacology and experimental therapeutics 20040801

• High-dose intravenous vitamin C is not associated with an increase of pro-oxidative biomarkers.

  European journal of clinical nutrition 20040801

• Altered calcium-induced exocytosis in neutrophils from allergic patients.

  International archives of allergy and immunology 20040801

• Shift in nucleotide conformational equilibrium contributes to increased rate of catalysis of GpAp versus GpA in barnase.

  Proteins 20040801

• KMUP-1, a xanthine derivative, induces relaxation of guinea-pig isolated trachea: the role of the epithelium, cyclic nucleotides and K+ channels.

  British journal of pharmacology 20040801

• Drug design and synthesis of epsilon opioid receptor agonist: 17-(cyclopropylmethyl)-4,5alpha-epoxy-3,6beta-dihydroxy-6,14-endoethenomorphinan-7alpha-(N-methyl-N-phenethyl)carboxamide (TAN-821) inducing antinociception mediated by putative epsilon opioid receptor.

  Bioorganic & medicinal chemistry 20040801

• A highly pathogenic porcine reproductive and respiratory syndrome virus generated from an infectious cDNA clone retains the in vivo virulence and transmissibility properties of the parental virus.

  Virology 20040801

• Apoptosis in ischemic renal injury: roles of GTP depletion and p53.

  Kidney international 20040801

• Dynamic nucleation of Golgi apparatus assembly from the endoplasmic reticulum in interphase hela cells.

  Traffic (Copenhagen, Denmark) 20040801

• High-affinity interactions between human alpha1A-adrenoceptor C-terminal splice variants produce homo- and heterodimers but do not generate the alpha1L-adrenoceptor.

  Molecular pharmacology 20040801

• Identification of a novel site within G protein alpha subunits important for specificity of receptor-G protein interaction.

  Molecular pharmacology 20040801

• Sevoflurane promotes endothelium-dependent smooth muscle relaxation in isolated human omental arteries and veins.

  Anesthesia and analgesia 20040801

• In vivo selection reveals combinatorial controls that define a critical exon in the spinal muscular atrophy genes.

  RNA (New York, N.Y.) 20040801

• The antibody-capture [(35)S]GTPgammaS scintillation proximity assay: a powerful emerging technique for analysis of GPCR pharmacology.

  Trends in pharmacological sciences 20040801

• A reversible gel for chiral separations.

  Analytical chemistry 20040801

• Regulation of dopamine D-receptor activation in vivo by protein phosphatase 2B (calcineurin).

  Journal of neurochemistry 20040801

• Beyond genetics--the emerging role of epigenetic changes in hematopoietic malignancies.

  International journal of hematology 20040801

• Enzymatic transesterification of purine nucleoside having a low solubility in organic medium.

  Biotechnology letters 20040801

• Effect of insulin on spontaneous and progesterone-induced GVBD on Bufo arenarum denuded oocytes.

  Zygote (Cambridge, England) 20040801

• Staurosporine restores GTPgammaS induced block of rapid endocytosis in chromaffin cells.

  FEBS letters 20040730

• Transient silylation of the guanosine O6 and amino groups facilitates N-acylation.

  Organic letters 20040722

• Isolation and characterization of the human tRNA-(N1G37) methyltransferase (TRM5) and comparison to the Escherichia coli TrmD protein.

  Biochemistry 20040720

• Clinical significance of elongation factor-1 delta mRNA expression in oesophageal carcinoma.

  British journal of cancer 20040719

• Changes in purine levels and adenosine receptors in kindled seizures in the rat.

  Neuroreport 20040719

• Increased baclofen-stimulated G protein coupling and deactivation in rat brain cortex during development.

  Brain research. Developmental brain research 20040719

• Differential effects of gestational buprenorphine, naloxone, and methadone on mesolimbic mu opioid and ORL1 receptor G protein coupling.

  Brain research. Developmental brain research 20040719

• Identification of the region in Cdc42 that confers the binding specificity to activated Cdc42-associated kinase.

  The Journal of biological chemistry 20040716

• CCL3, acting via the chemokine receptor CCR5, leads to independent activation of Janus kinase 2 (JAK2) and Gi proteins.

  FEBS letters 20040716

• Actions downstream of cyclic GMP/protein kinase G can reverse protein kinase C-mediated phosphorylation of CPI-17 and Ca²⁺ sensitization in smooth muscle.

  The Journal of biological chemistry 20040709

• Characterization of the pharmacology of imidazolidinedione derivatives at cannabinoid CB1 and CB2 receptors.

  European journal of pharmacology 20040708

• Conformational properties of shape modified nucleosides--fleximers.

  Journal of the American Chemical Society 20040707

• Reactions of 9-substituted guanines with bromomalondialdehyde in aqueous solution predominantly yield glyoxal-derived adducts.

  Organic & biomolecular chemistry 20040707

• Effect of nonsteroidal anti-inflammatory drugs on beta-catenin protein levels and catenin-related transcription in human colorectal cancer cells.

  British journal of cancer 20040705

• Rapid desensitization of G protein-gated inwardly rectifying K(+) currents is determined by G protein cycle.

  American journal of physiology. Cell physiology 20040701

• Cloning and pharmacological characterization of CXCR1 and CXCR2 from Macaca fascicularis.

  The Journal of pharmacology and experimental therapeutics 20040701

• Prostaglandin E2 activates outwardly rectifying Cl(-) channels via a cAMP-dependent pathway and reduces cell motility in rat osteoclasts.

  American journal of physiology. Cell physiology 20040701

• Guanine nucleotides inhibit NMDA and kainate-induced neurotoxicity in cultured rat hippocampal and neocortical neurons.

  Neurochemistry international 20040701

• Antitussive profile of the NOP agonist Ro-64-6198 in the guinea pig.

  Pharmacology 20040701

• Solution structure of hypothetical Nudix hydrolase DR0079 from extremely radiation-resistant Deinococcus radiodurans bacterium.

  Proteins 20040701

• Cannabinoid signaling in rat cerebellar granule cells: G-protein activation, inhibition of glutamate release and endogenous cannabinoids.

  Neuropharmacology 20040701

• Analysis of the monocyte chemoattractant protein 1 -2518 promoter polymorphism in patients with multiple sclerosis.

  Tissue antigens 20040701

• 'Low' concentrations of sodium fluoride inhibit neurotransmitter release from the guinea-pig superior cervical ganglion.

  Neuroscience letters 20040701

• Biochemical characterization of the coating mechanism of the endosomal donor compartment of synaptic vesicles.

  Neurochemical research 20040701

• Adenosine down-regulates the surface expression of dipeptidyl peptidase IV on HT-29 human colorectal carcinoma cells: implications for cancer cell behavior.

  The American journal of pathology 20040701

• Anesthetics inhibit acetylcholine-promoted guanine nucleotide exchange of heterotrimeric G proteins of airway smooth muscle.

  Anesthesiology 20040701

• Inhibition of melatonin-induced ascorbic acid and LHRH release by a nitric oxide synthase and cyclic GMP inhibitor.

  Experimental biology and medicine (Maywood, N.J.) 20040701

• The dg2 (for) gene confers a renal phenotype in Drosophila by modulation of cGMP-specific phosphodiesterase.

  The Journal of experimental biology 20040701

• Inhibition of neutral sodium absorption by a prostaglandin analogue in patients with cystic fibrosis.

  Gastroenterology 20040701

• Ontogenetic profile of glutamate uptake in brain structures slices from rats: sensitivity to guanosine.

  Mechanisms of ageing and development 20040701

• Functional responses to the cannabinoid agonist WIN 55,212-2 in neonatal rats of both genders: influence of weaning.

  Pharmacology, biochemistry, and behavior 20040701

• Impaired synthesis and action of antiaggregating cyclic nucleotides in platelets from obese subjects: possible role in platelet hyperactivation in obesity.

  European journal of clinical investigation 20040701

• Use of a native affinity ligand for the detection of G proteins by capillary isoelectric focusing with laser-induced fluorescence detection.

  Electrophoresis 20040701

• Receptor binding kinetics and cellular responses of six N-formyl peptide agonists in human neutrophils.

  Biochemistry 20040629

• Cloning and pharmacological characterisation of the guinea pig 5-ht5A receptor.

  European journal of pharmacology 20040628

• Na+ modulation, inverse agonism, and anorectic potency of 4-phenylpiperidine opioid antagonists.

  European journal of pharmacology 20040628

• Identification and characterization of AGS4: a protein containing three G-protein regulatory motifs that regulate the activation state of Gialpha.

  The Journal of biological chemistry 20040625

• The Escherichia coli 3-methyladenine DNA glycosylase AlkA has a remarkably versatile active site.

  The Journal of biological chemistry 20040625

• Crystal structure of transglutaminase 3 in complex with GMP: structural basis for nucleotide specificity.

  The Journal of biological chemistry 20040618

• Morphine-induced changes in delta opioid receptor trafficking are linked to somatosensory processing in the rat spinal cord.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040616

• Vesicle transport in oligodendrocytes: probable role of Rab40c protein.

  Journal of neuroscience research 20040615

• Distinct origins of tRNA(m1G37) methyltransferase.

  Journal of molecular biology 20040611

• Initial structure-activity relationships of lysophosphatidic acid receptor antagonists: discovery of a high-affinity LPA1/LPA3 receptor antagonist.

  Bioorganic & medicinal chemistry letters 20040607

• Inhibition by bis(7)-tacrine of 5-HT-activated current in rat TG neurons.

  Neuroreport 20040607

• Long-chain adducts of trans-4-hydroxy-2-nonenal to DNA bases cause recombination, base substitutions and frameshift mutations in M13 phage.

  Mutation research 20040604

• Agonist-induced serotonin 2A receptor desensitization in the rat frontal cortex and hypothalamus.

  The Journal of pharmacology and experimental therapeutics 20040601

• S32504, a novel naphtoxazine agonist at dopamine D3/D2 receptors: I. Cellular, electrophysiological, and neurochemical profile in comparison with ropinirole.

  The Journal of pharmacology and experimental therapeutics 20040601

• A high-throughput and sensitive methodology for the quantification of urinary 8-hydroxy-2'-deoxyguanosine: measurement with gas chromatography-mass spectrometry after single solid-phase extraction.

  The Biochemical journal 20040601

• Opioid peptide receptor studies. 17. Attenuation of chronic morphine effects after antisense oligodeoxynucleotide knock-down of RGS9 protein in cells expressing the cloned Mu opioid receptor.

  Synapse (New York, N.Y.) 20040601

• Nucleosides and ODN electrochemical detection onto boron doped diamond electrodes.

  Bioelectrochemistry (Amsterdam, Netherlands) 20040601

• G protein-mediated dysfunction of excitation-contraction coupling in ileal inflammation.

  American journal of physiology. Gastrointestinal and liver physiology 20040601

• Enhanced G-protein activation by a mixture of Abeta(25-35), Abeta(1-40/42) and zinc.

  Journal of neurochemistry 20040601

• Choline availability modulates human neuroblastoma cell proliferation and alters the methylation of the promoter region of the cyclin-dependent kinase inhibitor 3 gene.

  Journal of neurochemistry 20040601

• Plasma purine nucleoside phosphorylase in cancer patients.

  Clinica chimica acta; international journal of clinical chemistry 20040601

• Expression of natriuretic peptides, nitric oxide synthase, and guanylate cyclase activity in frog mesonephros during the annual cycle.

  General and comparative endocrinology 20040601

• Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon.

  British journal of pharmacology 20040601

• Unique roles of the rrn P2 rRNA promoters in Escherichia coli.

  Molecular microbiology 20040601

• The quormone degradation system of Agrobacterium tumefaciens is regulated by starvation signal and stress alarmone (p)ppGpp.

  Molecular microbiology 20040601

• Molecular cloning of a putative membrane form guanylyl cyclase from the crayfish Procambarus clarkii.

  Journal of experimental zoology. Part A, Comparative experimental biology 20040601

• Effects of RNA polymerase modifications on transcription-induced negative supercoiling and associated R-loop formation.

  Molecular microbiology 20040601

• The bacterial signal molecule, ppGpp, regulates Salmonella virulence gene expression.

  Molecular microbiology 20040601

• Renal secretion of the antiviral nucleoside analog AM188 is inhibited by probenecid, p-aminohippuric acid, and cimetidine in the isolated perfused rat kidney.

  Pharmaceutical research 20040601

• Phospholipase C involvement in activation of the muscarinic receptor-operated cationic current in Guinea pig ileal smooth muscle cells.

  Journal of pharmacological sciences 20040601

• Cooperative effects in the photophysical properties of self-associated triguanosine diphosphates.

  Photochemistry and photobiology 20040601

• Structural plasticity of the adult brain: how animal models help us understand brain changes in depression and systemic disorders related to depression.

  Dialogues in clinical neuroscience 20040601

• Identification of a G protein-coupled receptor specifically responsive to beta-alanine.

  The Journal of biological chemistry 20040528

• Artificial genetic systems: exploiting the 'aromaticity' formalism to improve the tautomeric ratio for isoguanosine derivatives.

  The Journal of organic chemistry 20040528

• Cholesterol modulates ligand binding and G-protein coupling to serotonin(1A) receptors from bovine hippocampus.

  Biochimica et biophysica acta 20040527

• Cadmium inhibits GABA-activated ion currents by increasing intracellular calcium level in snail neurons.

  Brain research 20040522

• The M3 receptor-mediated K(+) current (IKM3), a G(q) protein-coupled K(+) channel.

  The Journal of biological chemistry 20040521

• SAR development of a selective 5-HT1D antagonist/serotonin reuptake inhibitor lead using rapid parallel synthesis.

  Bioorganic & medicinal chemistry letters 20040517

• Single base oligodeoxyguanosine upregulates Fas ligand release by nonspecific cytotoxic cells.

  Developmental and comparative immunology 20040517

• Mutation of leucine-92 selectively reduces the apparent affinity of inosine, guanosine, NBMPR [S6-(4-nitrobenzyl)-mercaptopurine riboside] and dilazep for the human equilibrative nucleoside transporter, hENT1.

  The Biochemical journal 20040515

• Binding differences of human and amphibian corticotropin-releasing factor type 1 (CRF(1)) receptors: identification of amino acids mediating high-affinity astressin binding and functional antagonism.

  Regulatory peptides 20040515

• Cinnamic amides of (S)-2-(aminomethyl)pyrrolidines are potent H3 antagonists.

  Bioorganic & medicinal chemistry 20040515

• Influence of electric charge variation at residues 209 and 159 on the interaction of eIF4E with the mRNA 5' terminus.

  Biochemistry 20040511

• Differential inhibition of adenylyl cyclase isoforms and soluble guanylyl cyclase by purine and pyrimidine nucleotides.

  The Journal of biological chemistry 20040507

• 4-(omega-(alkyloxy)alkyl)-1H-imidazole derivatives as histamine H(3) receptor antagonists/agonists.

  Journal of medicinal chemistry 20040506

• SRA880, in vitro characterization of the first non-peptide somatostatin sst(1) receptor antagonist.

  Neuroscience letters 20040506

• N,N-dialkyl-4-[(8-azabicyclo[3.2.1]-oct-3-ylidene)phenylmethyl]benzamides, potent, selective delta opioid agonists.

  Bioorganic & medicinal chemistry letters 20040503

• The cofactor of the iron-sulfur cluster free hydrogenase hmd: structure of the light-inactivation product.

  Angewandte Chemie (International ed. in English) 20040503

• Guanine derivatives modulate L-glutamate uptake into rat brain synaptic vesicles.

  Neurochemistry international 20040501

• P2Y purinergic receptor regulation of CFTR chloride channels in mouse cardiac myocytes.

  The Journal of physiology 20040501

• Renal interstitial guanosine cyclic 3', 5'-monophosphate mediates pressure-natriuresis via protein kinase G.

  Hypertension (Dallas, Tex. : 1979) 20040501

• delta-Opioid receptor antagonists inhibit GIRK channel currents in acutely dissociated brainstem neurons of rat.

  Brain research 20040501

• Investigation of the mechanism of agonist and inverse agonist action at D2 dopamine receptors.

  Biochemical pharmacology 20040501

• The antiapoptotic effect of guanosine is mediated by the activation of the PI 3-kinase/AKT/PKB pathway in cultured rat astrocytes.

  Glia 20040501

• Regulation of uterine function: a biochemical conundrum in the regulation of smooth muscle relaxation.

  Molecular pharmacology 20040501

• Two relA/spoT homologous genes are involved in the morphological and physiological differentiation of Streptomyces clavuligerus.

  Microbiology (Reading, England) 20040501

• Arg(184)His mutant GTP cyclohydrolase I, causing recessive hyperphenylalaninemia, is responsible for dopa-responsive dystonia with parkinsonism: a case report.

  Movement disorders : official journal of the Movement Disorder Society 20040501

• Competition between lithium and magnesium ions for the G-protein transducin in the guanosine 5'-diphosphate bound conformation.

  Journal of inorganic biochemistry 20040501

• GABA(B) receptors in 5-HT transporter- and 5-HT1A receptor-knock-out mice: further evidence of a transduction pathway shared with 5-HT1A receptors.

  Journal of neurochemistry 20040501

• Nucleotides in sow colostrum and milk at different stages of lactation.

  Journal of animal science 20040501

• Antibodies to guanosine triphosphate misidentified as anti-double-stranded DNA antibodies in a patient with antinuclear antibody-negative lupus, due to buckling of insolubilized assay DNA.

  Arthritis and rheumatism 20040501

• The receptor-Galpha fusion protein as a tool for ligand screening: a model study using a nociceptin receptor-Galphai2 fusion protein.

  Journal of biochemistry 20040501

• Inhibitors of measles virus.

  Antiviral chemistry & chemotherapy 20040501

• A conformationally constrained nucleotide analogue controls the folding topology of a DNA g-quadruplex.

  Journal of the American Chemical Society 20040428

• Galphai1 and Galphai3 differentially interact with, and regulate, the G protein-activated K+ channel.

  The Journal of biological chemistry 20040423

• Cholinergic modulation of L-type calcium current in isolated sensory hair cells of the statocyst of octopus, Eledone cirrhosa.

  Neuroscience letters 20040422

• CG base pair recognition by substituted phenylimidazole nucleosides.

  Organic & biomolecular chemistry 20040421

• Carbon monoxide: to boldly go where NO has gone before.

  Science's STKE : signal transduction knowledge environment 20040420

• Anticonvulsant effect of GMP depends on its conversion to guanosine.

  Brain research 20040416

• Cdc42 and mDia3 regulate microtubule attachment to kinetochores.

  Nature 20040415

• Nucleic acid analysis using an expanded genetic alphabet to quench fluorescence.

  Journal of the American Chemical Society 20040414

• Replication-dependent 65R-->K reversion in human immunodeficiency virus type 1 reverse transcriptase double mutant K65R + L74V.

  Virology 20040410

• Ca2+ and phosphatidylinositol 4,5-bisphosphate stabilize a Gbeta gamma-sensitive state of Ca V2 Ca 2+ channels.

  The Journal of biological chemistry 20040409

• Crystal structure of purine nucleoside phosphorylase from Thermus thermophilus.

  Journal of molecular biology 20040409

• Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine.

  Molecular cell 20040409

• Effects of chronic ethanol administration and ethanol withdrawal on cyclic guanosine 3',5'-monophosphate (cGMP) levels in the rat brain.

  Drug and alcohol dependence 20040409

• Guanosine protects SH-SY5Y cells against beta-amyloid-induced apoptosis.

  Neuroreport 20040409

• Alkylation of guanosine and 2'-deoxyguanosine by o-quinone alpha-(p-anisyl)methide in aqueous solution.

  Organic & biomolecular chemistry 20040407

• DNA nucleosides and their radical anions: molecular structures and electron affinities.

  Journal of the American Chemical Society 20040407

• Real-time analysis of ternary complex on particles: direct evidence for partial agonism at the agonist-receptor-G protein complex assembly step of signal transduction.

  The Journal of biological chemistry 20040402

• Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate.

  The Journal of biological chemistry 20040402

• Furin is a chemokine-modifying enzyme: in vitro and in vivo processing of CXCL10 generates a C-terminally truncated chemokine retaining full activity.

  The Journal of biological chemistry 20040402

• Functional coupling of the nociceptin/orphanin FQ receptor in dog brain membranes.

  Brain research 20040402

• Conformational antagonism between opposing active sites in a bifunctional RelA/SpoT homolog modulates (p)ppGpp metabolism during the stringent response [corrected].

  Cell 20040402

• Among circulating hematopoietic cells, B-CLL uniquely expresses functional EPAC1, but EPAC1-mediated Rap1 activation does not account for PDE4 inhibitor-induced apoptosis.

  Blood 20040401

• Description of glucose transport in isolated bovine mammary epithelial cells by a three-compartment model.

  American journal of physiology. Cell physiology 20040401

• Delta-opioid agonists: differential efficacy and potency of SNC80, its 3-OH (SNC86) and 3-desoxy (SNC162) derivatives in Sprague-Dawley rats.

  The Journal of pharmacology and experimental therapeutics 20040401

• Redox modulation of Gi protein expression and adenylyl cyclase signaling: role of nitric oxide.

  Antioxidants & redox signaling 20040401

• Practical and general synthesis of 5'-adenylated RNA (5'-AppRNA).

  RNA (New York, N.Y.) 20040401

• The hyperthermophilic origin of life revisited.

  Biochemical Society transactions 20040401

• Deep knot structure for construction of active site and cofactor binding site of tRNA modification enzyme.

  Structure (London, England : 1993) 20040401

• Cyclic di-guanosine-monophosphate comes of age: a novel secondary messenger involved in modulating cell surface structures in bacteria?

  Current opinion in microbiology 20040401

• Role of ATP-sensitive K+ channels in relaxation of penile resistance arteries.

  Urology 20040401

• Time-dependent inhibition of G protein-coupled receptor signaling by local anesthetics.

  Anesthesiology 20040401

• Characterization and quantitative analysis of DNA adducts formed from lower chlorinated PCB-derived quinones.

  Chemical research in toxicology 20040401

• Melatonin binding sites in the brain of European sea bass (Dicentrarchus labrax).

  Zoological science 20040401

• Involvement of G proteins in the mycelial photoresponses of Phycomyces.

  Photochemistry and photobiology 20040401

• Detection of cannabinoid CB1, adenosine A1, muscarinic acetylcholine, and GABA(B) receptor-dependent G protein activity in transducin-deactivated membranes and autoradiography sections of rat retina.

  Cellular and molecular neurobiology 20040401

• [Study on the chemical constituents of Selaginella tamariscina (Beauv.) Spring].

  Yao xue xue bao = Acta pharmaceutica Sinica 20040401

• Ligand binding characteristics of the human serotonin1A receptor heterologously expressed in CHO cells.

  Bioscience reports 20040401

• Constitutive activity of the serotonin2C receptor inhibits in vivo dopamine release in the rat striatum and nucleus accumbens.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040331

• Application of an immunoperoxidase staining method for detection of 7,8-dihydro-8-oxodeoxyguanosine as a biomarker of chemical-induced oxidative stress in marine organisms.

  Aquatic toxicology (Amsterdam, Netherlands) 20040330

• Clostridium perfringens alpha-toxin activates the sphingomyelin metabolism system in sheep erythrocytes.

  The Journal of biological chemistry 20040326

• Structure-activity study of the ORL1 antagonist Ac-Arg-D-Cha-Qaa-D-Arg-D-p-ClPhe-NH2.

  Journal of medicinal chemistry 20040325

• Neurochemical and behavioral alterations in glucocorticoid receptor-impaired transgenic mice after chronic mild stress.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040317

• Ceramide inhibition of phospholipase D and its relationship to RhoA and ARF1 translocation in GTP gamma S-stimulated polymorphonuclear leukocytes.

  Blood 20040315

• Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif.

  The Biochemical journal 20040315

• Oxidative stress in severe pulmonary hypertension.

  American journal of respiratory and critical care medicine 20040315

• Reactive oxygen species derived from the mitochondrial respiratory chain are not responsible for the basal levels of oxidative base modifications observed in nuclear DNA of Mammalian cells.

  Free radical biology & medicine 20040315

• Adenosine-dependent assembly of aptazyme-functionalized gold nanoparticles and its application as a colorimetric biosensor.

  Analytical chemistry 20040315

• Transcription factors NF-YA regulate the induction of human OGG1 following DNA-alkylating agent methylmethane sulfonate (MMS) treatment.

  The Journal of biological chemistry 20040312

• Munc13-4 is a GTP-Rab27-binding protein regulating dense core granule secretion in platelets.

  The Journal of biological chemistry 20040312

• Action of the muscarinic toxin MT7 on agonist-bound muscarinic M1 receptors.

  European journal of pharmacology 20040308

• Antiobesity effects of A-331440, a novel non-imidazole histamine H3 receptor antagonist.

  European journal of pharmacology 20040308

• Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8.

  Science (New York, N.Y.) 20040305

• Site-specific modification of Epstein-Barr virus-encoded RNA 1 with N2-benzylguanosine limits the binding sites occupied by PKR.

  Chembiochem : a European journal of chemical biology 20040305

• Guanosine distribution and oxidation resistance in eight eukaryotic genomes.

  Journal of the American Chemical Society 20040303

• Reduced renal dopamine D1 receptor function in streptozotocin-induced diabetic rats.

  American journal of physiology. Renal physiology 20040301

• Epinephrine-induced hyperpolarization of islet cells without KATP channels.

  American journal of physiology. Endocrinology and metabolism 20040301

• Characterization of N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyano-phenyl)-N-[1-(2-cyclopentyl-ethyl)-piperidin-4yl]acrylamide (JNJ-5207787), a small molecule antagonist of the neuropeptide Y Y2 receptor.

  The Journal of pharmacology and experimental therapeutics 20040301

• Actions of noradrenaline on substantia gelatinosa neurones in the rat spinal cord revealed by in vivo patch recording.

  The Journal of physiology 20040301

• Guanine nucleotide depletion triggers cell cycle arrest and apoptosis in human neuroblastoma cell lines.

  International journal of cancer 20040301

• An autoradiographic study of the influence of pindolol upon [35S]GTPgammaS binding in rat, guinea pig and human brain.

  The international journal of neuropsychopharmacology 20040301

• Single cGMP-activated Ca(+)-dependent Cl(-) channels in rat mesenteric artery smooth muscle cells.

  The Journal of physiology 20040301

• Functional group recognition at the aminoacylation and editing sites of E. coli valyl-tRNA synthetase.

  RNA (New York, N.Y.) 20040301

• The effects of hexanol on Galpha(i) subunits of heterotrimeric G proteins.

  Anesthesia and analgesia 20040301

• Inhibition of thrombosis by a novel platelet selective S-nitrosothiol compound without hemodynamic side effects.

  Cardiovascular research 20040301

• Attenuation of renal injury in db/db mice overexpressing superoxide dismutase: evidence for reduced superoxide-nitric oxide interaction.

  Diabetes 20040301

• Carbon monoxide in biology and medicine.

  BioEssays : news and reviews in molecular, cellular and developmental biology 20040301

• Oral administration of guanosine impairs inhibitory avoidance performance in rats and mice.

  Neurobiology of learning and memory 20040301

• Nitrosation of glycine ethyl ester and ethyl diazoacetate to give the alkylating agent and mutagen ethyl chloro(hydroximino)acetate.

  Chemical research in toxicology 20040301

• Evidence for tight coupling of Gi protein-mediated lysophosphatidic acid receptor to stimulated cytokine production in ovarian cancer cell.

  American journal of obstetrics and gynecology 20040301

• A purified agonist-activated G-protein coupled receptor: truncated octopus Acid Metarhodopsin.

  Zoological science 20040301

• PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP.

  The European journal of neuroscience 20040301

• Effect of 2'-deoxyisoguanosine on the growth of human tumor and normal cell lines.

  Eksperimental'naia onkologiia 20040301

• Purine nucleosides support the neurite outgrowth of primary rat cerebellar granule cells after hypoxia.

  European journal of cell biology 20040301

• Complexes of copper(II) with adenosine or guanosine nucleosides, nucleotides 5'-monophosphate, 2'-deoxynucleosides or 2'-deoxynucleotides 5'-monophosphate in aqueous solution.

  Annali di chimica 20040301

• Melanopsin--shedding light on the elusive circadian photopigment.

  Chronobiology international 20040301

• Relationship between growth rate and ATP concentration in Escherichia coli: a bioassay for available cellular ATP.

  The Journal of biological chemistry 20040227

• Activation of type I phosphatidylinositol 4-phosphate 5-kinase isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42.

  The Journal of biological chemistry 20040227

• Monkey corticotropin-releasing factor1 receptor: Complementary DNA cloning and pharmacological characterization.

  Life sciences 20040227

• Structural basis for the coordinated regulation of transglutaminase 3 by guanine nucleotides and calcium/magnesium.

  The Journal of biological chemistry 20040220

• Structural insights into the interaction of ROCKI with the switch regions of RhoA.

  The Journal of biological chemistry 20040220

• A Rho exchange factor mediates fMet-Leu-Phe-induced NF-kappaB activation in human peripheral blood monocytes.

  The Journal of biological chemistry 20040220

• Alpha-thrombin-mediated phosphatidylinositol 3-kinase activation through release of Gbetagamma dimers from Galphaq and Galphai2.

  The Journal of biological chemistry 20040220

• Formamidopyrimidines as major products in the low- and high-intensity UV irradiation of guanine derivatives.

  Journal of photochemistry and photobiology. B, Biology 20040220

• Minimum essential factors required for vesicle mobilization at hippocampal synapses.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040218

• Molecular pharmacology of the ovine melatonin receptor: comparison with recombinant human MT1 and MT2 receptors.

  Biochemical pharmacology 20040215

• Relationship between the antinociceptive response to desipramine and changes in GABAB receptor function and subunit expression in the dorsal horn of the rat spinal cord.

  Biochemical pharmacology 20040215

• Modulation of Ca2+ sensitivity by cyclic nucleotides in smooth muscle from protein kinase G-deficient mice.

  The Journal of biological chemistry 20040213

• Region-dependent G-protein activation by kappa-opioid receptor agonists in the mouse brain.

  Neuroscience letters 20040212

• Effect of amine ligand bulk on the interaction of methionine with platinum(II) diamine complexes.

  Inorganic chemistry 20040209

• Design for a binary synapse.

  Neuron 20040205

• Selective transmission of single photon responses by saturation at the rod-to-rod bipolar synapse.

  Neuron 20040205

• Recovery of sensorimotor gating without G protein adaptation after repeated D2-like dopamine receptor agonist treatment in rats.

  The Journal of pharmacology and experimental therapeutics 20040201

• Characterization of mu opioid receptor binding and G protein coupling in rat hypothalamus, spinal cord, and primary afferent neurons during inflammatory pain.

  The Journal of pharmacology and experimental therapeutics 20040201

• Basal signaling activity of mu opioid receptor in mouse brain: role in narcotic dependence.

  The Journal of pharmacology and experimental therapeutics 20040201

• Receptor-controlled phosphorylation of alpha 1 soluble guanylyl cyclase enhances nitric oxide-dependent cyclic guanosine 5'-monophosphate production in pituitary cells.

  Molecular endocrinology (Baltimore, Md.) 20040201

• Specific mutations in the HEXA gene among Iraqi Jewish Tay-Sachs disease carriers: dating of founder ancestor.

  Neurogenetics 20040201

• Production and role of extracellular guanosine cyclic 3', 5' monophosphate in sodium uptake in human proximal tubule cells.

  Hypertension (Dallas, Tex. : 1979) 20040201

• Characterization of melatonin binding sites in the brain and retina of the frog Rana perezi.

  General and comparative endocrinology 20040201

• Gamma-hydroxybutyric acid, unlike gamma-aminobutyric acid, does not stimulate Gi/Go proteins in rat brain membranes.

  Basic & clinical pharmacology & toxicology 20040201

• Enhanced morphine withdrawal and micro -opioid receptor G-protein coupling in A2A adenosine receptor knockout mice.

  Journal of neurochemistry 20040201

• Down-regulation of rat brain adenosine A1 receptors at the end of pregnancy.

  Journal of neurochemistry 20040201

• Sphingosine-1-phosphate induces proliferation and morphological changes of neural progenitor cells.

  Journal of neurochemistry 20040201

• Nitrergic-purinergic interactions in rat distal colon motility.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20040201

• Decreased cerebrospinal fluid cGMP levels in patients with amyotrophic lateral sclerosis.

  Journal of neural transmission (Vienna, Austria : 1996) 20040201

• NO-cGMP signaling molecules in the rat epithelial rests of Malassez.

  European journal of oral sciences 20040201

• Upregulation of CB1 receptors and agonist-stimulated [35S]GTPgammaS binding in the prefrontal cortex of depressed suicide victims.

  Molecular psychiatry 20040201

• Effect of the manganese ion on human alpha3/4 fucosyltransferase III activity.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20040201

• Pituitary adenylate cyclase activating polypeptide-mediated intracrine signaling in the testicular germ cells.

  Endocrine 20040201

• Pharmacology of polymorphic variants of the human 5-HT1A receptor.

  Biochemical pharmacology 20040201

• Diphenylamine-2-carboxylic acid potentiates the cyclic nucleotides-mediated relaxation of porcine coronary artery: possible involvement of the inhibitory effect on the efflux of cyclic nucleotides.

  Vascular pharmacology 20040201

• The 5-hydroxytryptamine(1A) receptor is stably palmitoylated, and acylation is critical for communication of receptor with Gi protein.

  The Journal of biological chemistry 20040130

• Dissociated histaminergic neuron cultures from the tuberomammillary nucleus of rats: culture methods and ghrelin effects.

  Journal of neuroscience methods 20040130

• G-quartets 40 years later: from 5'-GMP to molecular biology and supramolecular chemistry.

  Angewandte Chemie (International ed. in English) 20040130

• Inhibition of N-type voltage-activated calcium channels in rat dorsal root ganglion neurons by P2Y receptors is a possible mechanism of ADP-induced analgesia.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040128

• Platinum complexes with NH groups on the carrier ligand and with only one guanine or hypoxanthine derivative. Informative models for assessing relative nucleobase and nucleotide hydrogen-bond interactions with amine ligands in solution.

  Inorganic chemistry 20040126

• Conformers of guanosines and their vibrations in the electronic ground and excited states, as revealed by double-resonance spectroscopy and ab initio calculations.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20040123

• Substitution reactions of [Pt(terpy)X]2+ with some biologically relevant ligands. Synthesis and crystal structure of [Pt(terpy)(cyst-S)](ClO4)2.0.5H2O and [Pt(terpy)(guo-N7)](ClO4)2.0.5guo.1.5H2O.

  Dalton transactions (Cambridge, England : 2003) 20040121

• Independent folding and conformational changes of the barnase module in the VL-barnase immunofusion: calorimetric evidence.

  FEBS letters 20040116

• Effect of phosphodiesterase-5 inhibitor, sildenafil (Viagra), in animal models of airways disease.

  American journal of respiratory and critical care medicine 20040115

• Estimation of guanine deaminase using guanosine as a 'prosubstrate'.

  Analytical biochemistry 20040115

• Modulation of A1 adenosine receptor signaling by peroxynitrite.

  Biochemical pharmacology 20040115

• Sulindac targets nuclear beta-catenin accumulation and Wnt signalling in adenomas of patients with familial adenomatous polyposis and in human colorectal cancer cell lines.

  British journal of cancer 20040112

• Minihelix-containing RNAs mediate exportin-5-dependent nuclear export of the double-stranded RNA-binding protein ILF3.

  The Journal of biological chemistry 20040109

• Microchip capillary electrophoresis with a boron-doped diamond electrode for rapid separation and detection of purines.

  Journal of chromatography. A 20040102

• Characterization of M2 muscarinic receptor activation of different G protein subtypes.

  Neurochemistry international 20040101

• Assay of G protein-coupled receptor activation of G proteins in native cell membranes using [35S]GTP gamma S binding.

  Methods in molecular biology (Clifton, N.J.) 20040101

• A combination of oral sildenafil and beraprost ameliorates pulmonary hypertension in rats.

  American journal of respiratory and critical care medicine 20040101

• Inhibition of G protein-coupled and ATP-sensitive potassium currents by 2-methyl-3-(3,5-diiodo-4-carboxymethoxybenzyl)benzofuran (KB130015), an amiodarone derivative.

  The Journal of pharmacology and experimental therapeutics 20040101

• In situ evidence of an alternative oxidase and an uncoupling protein in the respiratory chain of Aspergillus fumigatus.

  The international journal of biochemistry & cell biology 20040101

• Adenine nucleotides inhibit recombinant N-type calcium channels via G protein-coupled mechanisms in HEK 293 cells; involvement of the P2Y13 receptor-type.

  British journal of pharmacology 20040101

• Carbachol in the pontine reticular formation of C57BL/6J mouse decreases acetylcholine release in prefrontal cortex.

  Neuroscience 20040101

• Dynamics of the IRE RNA hairpin loop probed by 2-aminopurine fluorescence and stochastic dynamics simulations.

  RNA (New York, N.Y.) 20040101

• Refinement of the structure of human Rab5a GTPase domain at 1.05 A resolution.

  Acta crystallographica. Section D, Biological crystallography 20040101

• The small GTP-binding protein RhoA regulates serotonin-induced Na+-current response in the neurons of Aplysia.

  Neuroscience research 20040101

• Metabolic changes induced by ischemia and cardioplegia: a study employing cardiac microdialysis in pigs.

  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20040101

• Urinary cyclic GMP excretion and blood pressure levels in a general population.

  Atherosclerosis 20040101

• Pharmacological characterisation of neuropeptide F (NPF)-induced effects on the motility of Mesocestoides corti (syn. Mesocestoides vogae) larvae.

  International journal for parasitology 20040101

• Thiochrome enhances acetylcholine affinity at muscarinic M4 receptors: receptor subtype selectivity via cooperativity rather than affinity.

  Molecular pharmacology 20040101

• Iron supplements: the quick fix with long-term consequences.

  Nutrition journal 20040101

• Alterations in the natriuretic hormone system related to cardiopulmonary bypass in infants with congestive heart failure.

  Pediatric cardiology 20040101

• Chronic ethanol consumption reduces delta-and mu-opioid receptor-stimulated G-protein coupling in rat brain.

  Alcoholism, clinical and experimental research 20040101

• Renal excretion mechanisms of the antiviral nucleoside analogue AM 188 in the rat isolated perfused kidney.

  Clinical and experimental pharmacology & physiology 20040101

• Excision by the human methylpurine DNA N-glycosylase of cyanuric acid, a stable and mutagenic oxidation product of 8-oxo-7,8-dihydroguanine.

  International journal of radiation biology 20040101

• A G-quadruplex ligand 3,3'-diethyloxadicarbocyanine iodide induces mitochondrion-mediated apoptosis but not decrease of telomerase activity in nasopharyngeal carcinoma NPC-TW01 cells.

  Pharmaceutical research 20040101

• Construction and characterization of a kappa opioid receptor devoid of all free cysteines.

  Protein engineering, design & selection : PEDS 20040101

• Effect of zaprinast on nitric oxide levels in serum and aortic tissue.

  Methods and findings in experimental and clinical pharmacology 20040101

• Isolated rat kidney perfused with dextran and bovine serum albumin: a stable model for investigating renal drug handling.

  Journal of pharmacological and toxicological methods 20040101

• Combination of chemical and enzymatic RNA synthesis.

  Methods in molecular biology (Clifton, N.J.) 20040101

• Dynamic light scattering and 31P NMR study of the self-assembly of deoxyguanosine 5'-monophosphate: the effect of added salt.

  The European physical journal. E, Soft matter 20040101

• Inhaled nitric oxide: another weapon in our armamentarium in the battle against acute hypoxic respiratory failure in preterm infants.

  Critical care (London, England) 20040101

• Functional cooperation of Ogg1 and Mutyh in preventing G: C-->T: a transversions in mice.

  Fukuoka igaku zasshi = Hukuoka acta medica 20040101

• Rearrangement reactions of 1,N2-isopropenoguanine cyclonucleosides.

  Nucleosides, nucleotides & nucleic acids 20040101

• Functionalization of guanosine and 2'-deoxyguanosine at C6: a modified Appel process and S(N)Ar displacement of imidazole.

  Nucleosides, nucleotides & nucleic acids 20040101

• Synthesis of nucleoside libraries on solid support. II. 2,6,8-Trisubstituted purine nucleosides using 8-bromoguanosine as precursor.

  Nucleosides, nucleotides & nucleic acids 20040101

• The excitation cascade of Limulus ventral photoreceptors: guanylate cyclase as the link between InsP3-mediated Ca2+ release and the opening of cGMP-gated channels.

  BMC neuroscience 20040101

• The stepwise supramolecular organisation of guanosine derivatives.

  Chemical record (New York, N.Y.) 20040101

• Synthesis and evaluation of ATP-binding site directed potential inhibitors of nucleoside triphosphatases/helicases and polymerases of hepatitis C and other selected Flaviviridae viruses.

  Antiviral chemistry & chemotherapy 20040101

• Partial A(1) adenosine receptor agonists from a molecular perspective and their potential use as chronic ventricular rate control agents during atrial fibrillation (AF).

  Current topics in medicinal chemistry 20040101

• Identification of substrates for adenosine deaminases that act on RNA.

  Methods in molecular biology (Clifton, N.J.) 20040101

• Losartan-induced attenuation of blood pressure in L-NAME hypertensive rats is associated with reversal of the enhanced expression of Gi alpha proteins.

  Journal of hypertension 20040101

• SIGI: score-based identification of genomic islands.

  BMC bioinformatics 20040101

• Bench-to-bedside review: understanding genetic predisposition to sepsis.

  Critical care (London, England) 20040101

• Mechanisms and consequences of methylating agent-induced SCEs and chromosomal aberrations: a long road traveled and still a far way to go.

  Cytogenetic and genome research 20040101

• Control of pyrimidine biosynthesis in 'Pseudomonas alkanolytica' ATCC 21034.

  Journal of basic microbiology 20040101

• Oxidative damage to DNA: an immunohistochemical approach for detection of 7,8-dihydro-8-oxodeoxyguanosine in marine organisms.

  Marine environmental research 20040101

• The synthesis of [([beta-D-ribofuranosyloxy)methyl]nucleosides.

  Nucleosides, nucleotides & nucleic acids 20040101

• Temperature-dependent interaction of the bovine hippocampal serotonin(1A) receptor with G-proteins.

  Molecular membrane biology 20040101

• A multi-scale study of industrial fermentation processes and their optimization.

  Advances in biochemical engineering/biotechnology 20040101

• Impact of 24 h continuous hypothermic perfusion on heart preservation by assessment of oxidative stress.

  Clinical transplantation 20040101

• Evidence that morphine tolerance may be regulated by endothelin in the neonatal rat.

  Biology of the neonate 20040101

• Physiology and pathophysiology of vascular signaling controlled by guanosine 3',5'-cyclic monophosphate-dependent protein kinase.

  Acta biochimica Polonica 20040101

• Determination of rat hepatic polyamines by electron-capture gas chromatography.

  Journal of pharmacological and toxicological methods 20040101

• Measurement of agonist-stimulated [35S]GTPgammaS binding to assess total G-protein and Galpha-subtype-specific activation by G-protein-coupled receptors.

  Methods in molecular biology (Clifton, N.J.) 20040101

• Analysis of function of receptor-G-protein and receptor-RGS fusion proteins.

  Methods in molecular biology (Clifton, N.J.) 20040101

• POSaM: a fast, flexible, open-source, inkjet oligonucleotide synthesizer and microarrayer.

  Genome biology 20040101

• Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors.

  BMC molecular biology 20040101

• A study comparing the actions of gabapentin and pregabalin on the electrophysiological properties of cultured DRG neurones from neonatal rats.

  BMC pharmacology 20040101

• Nitric oxide-an endogenous inhibitor of gastric acid secretion in isolated human gastric glands.

  BMC gastroenterology 20040101

• Cooperation in signal transduction of extracellular guanosine 5' triphosphate and nerve growth factor in neuronal differentiation of PC12 cells.

  Neuroscience 20040101

• Strickler-Berg analysis of excited singlet state dynamics in DNA and RNA nucleosides.

  Faraday discussions 20040101

• Regulation of RGS-RhoGEFs by Galpha12 and Galpha13 proteins.

  Methods in enzymology 20040101

• Purification and functional analysis of Ric-8A: a guanine nucleotide exchange factor for G-protein alpha subunits.

  Methods in enzymology 20040101

• Purification and in vitro functional analyses of RGS12 and RGS14 GoLoco motif peptides.

  Methods in enzymology 20040101

• Hypothesis: selective phosphodiesterase-5 inhibition improves outcome in preeclampsia.

  Medical hypotheses 20040101

• Regulation of tetrahydrobiopterin synthesis and bioavailability in endothelial cells.

  Cell biochemistry and biophysics 20040101

• Mechanism of ganciclovir uptake by rabbit retina and human retinal pigmented epithelium cell line ARPE-19.

  Current eye research 20040101

• Selective inhibition of c-Myb DNA-binding by RNA polymers.

  BMC biochemistry 20040101

• Characterization of G-rich and T-rich oligonucleotides using ion-pair reversed-phase high-performance liquid chromatography/tandem electrospray ionization mass spectrometry.

  European journal of mass spectrometry (Chichester, England) 20040101

• Genomic structure and cloning of two transcript isoforms of human Sp8.

  BMC genomics 20040101

• Intracerebroventricular administration of anti-endothelin-1 IgG selectively upregulates endothelin-A and kappa opioid receptors.

  Neuroscience 20040101

• [Escherichia coli ribosomes as the model to test new photoactivated tRNA analogues, containing 6-thioguanosine].

  Molekuliarnaia biologiia 20040101

• Expression of phospholipase D isozymes in scar and viable tissue in congestive heart failure due to myocardial infarction.

  Journal of cellular and molecular medicine 20040101

• In the ventral tegmental area, G-proteins and cAMP mediate the neurosteroid 3alpha,5alpha-THP's actions at dopamine type 1 receptors for lordosis of rats.

  Neuroendocrinology 20040101

• [Part of the matrix on the 5' side from codon in the E-segment is close to protein S26 on the human 80S ribosome].

  Molekuliarnaia biologiia 20040101

• Selective nitrosyl group transfer reaction to cytidine using oligonucleotides bearing S-nitrosothioguanosine.

  Nucleic acids symposium series (2004) 20040101

• Efficient syntheses of [2-(15)N]guanosine and 2'-deoxy[2-(15)N]guanosine derivatives.

  Nucleic acids symposium series (2004) 20040101

• Synthesis and base recognition ability of oligoribonucleotides incorporating 2'-O-methyl-3-deazaguanosine.

  Nucleic acids symposium series (2004) 20040101

• Design of 2'-O-Me RNA/ENA chimera oligonucleotides to induce exon skipping in dystrophin pre-mRNA.

  Nucleic acids symposium series (2004) 20040101

• Cigarette smoking as a risk factor of coronary artery disease and its effects on platelet function.

  Tobacco induced diseases 20040101

• Cloning and characterization of Xen-dorphin prohormone from Xenopus laevis: a new opioid-like prohormone distinct from proenkephalin and prodynorphin.

  The Journal of biological chemistry 20031226

• Identification of Drosophila neuropeptide receptors by G protein-coupled receptors-beta-arrestin2 interactions.

  The Journal of biological chemistry 20031226

• A new route to 2'-O-alkyl-2-thiouridine derivatives via 4-O-protection of the uracil base and hybridization properties of oligonucleotides incorporating these modified nucleoside derivatives.

  The Journal of organic chemistry 20031226

• Thermodynamic characterization of the binding of activator of G protein signaling 3 (AGS3) and peptides derived from AGS3 with G alpha i1.

  The Journal of biological chemistry 20031219

• Guanosine promotes myelination and functional recovery in chronic spinal injury.

  Neuroreport 20031219

• Direct activation by dopamine of recombinant human 5-HT1A receptors: comparison with human 5-HT2C and 5-HT3 receptors.

  Synapse (New York, N.Y.) 20031215

• Identification of relaxin-3/INSL7 as a ligand for GPCR142.

  The Journal of biological chemistry 20031212

• Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein-coupled receptor GPCR135.

  The Journal of biological chemistry 20031212

• The [35S]GTPgammaS binding assay: approaches and applications in pharmacology.

  Life sciences 20031212

• Water-mediated association provides an ion pair receptor.

  Journal of the American Chemical Society 20031210

• C-type natriuretic peptide decreases soluble guanylate cyclase levels by activating the proteasome pathway.

  Biochimica et biophysica acta 20031207

• Chronic treatment with interleukin-1beta attenuates contractions by decreasing the activities of CPI-17 and MYPT-1 in intestinal smooth muscle.

  The Journal of biological chemistry 20031205

• Direct observation of G-protein binding to the human delta-opioid receptor using plasmon-waveguide resonance spectroscopy.

  The Journal of biological chemistry 20031205

• MANT-substituted guanine nucleotides: a novel class of potent adenylyl cyclase inhibitors.

  Life sciences 20031205

• Identification of surrogate ligands for orphan G protein-coupled receptors.

  Life sciences 20031205

• Design of photoactivated DNA oxidizing agents: synthesis and study of photophysical properties and DNA interactions of novel viologen-linked acridines.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20031205

• Functional consequences of an in vivo mutation in exon 10 of the human GLUT1 gene.

  FEBS letters 20031204

• Silencing effect of CpG island hypermethylation and histone modifications on O6-methylguanine-DNA methyltransferase (MGMT) gene expression in human cancer.

  Oncogene 20031204

• Supramolecular helices via self-assembly of 8-oxoguanosines.

  Journal of the American Chemical Society 20031203

• SSR181507, a dopamine D(2) receptor antagonist and 5-HT(1A) receptor agonist. I: Neurochemical and electrophysiological profile.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20031201

• Site of action of the general anesthetic propofol in muscarinic M1 receptor-mediated signal transduction.

  The Journal of pharmacology and experimental therapeutics 20031201

• Comparison of [Dmt1]DALDA and DAMGO in binding and G protein activation at mu, delta, and kappa opioid receptors.

  The Journal of pharmacology and experimental therapeutics 20031201

• Neuropeptide Y Y4 receptor homodimers dissociate upon agonist stimulation.

  The Journal of pharmacology and experimental therapeutics 20031201

• (-)-PHCCC, a positive allosteric modulator of mGluR4: characterization, mechanism of action, and neuroprotection.

  Neuropharmacology 20031201

• An IQGAP-like protein is involved in actin assembly together with Cdc42 in the sea urchin egg.

  Cell motility and the cytoskeleton 20031201

• Evidence for protein kinase C-mediated activation of Rho-kinase in a porcine model of coronary artery spasm.

  Arteriosclerosis, thrombosis, and vascular biology 20031201

• A point mutation uncouples transducin-alpha from the photoreceptor RGS and effector proteins.

  Journal of neurochemistry 20031201

• An optimized approach to study endocannabinoid signaling: evidence against constitutive activity of rat brain adenosine A1 and cannabinoid CB1 receptors.

  British journal of pharmacology 20031201

• The ability to form full-length intron RNA circles is a general property of nuclear group I introns.

  RNA (New York, N.Y.) 20031201

• Neuroprotective effect of adenine on purkinje cell survival in rat cerebellar primary cultures.

  Journal of neuroscience research 20031201

• Rat brain guanosine binding site. Biological studies and pseudo-receptor construction.

  Bioorganic & medicinal chemistry 20031201

• Allosteric enhancers of A1 adenosine receptors increase receptor-G protein coupling and counteract Guanine nucleotide effects on agonist binding.

  Molecular pharmacology 20031201

• Expression and regulation of phospholipase D isoenzymes in human melanoma cells and primary melanocytes.

  Melanoma research 20031201

• Effects of phosphodiesterase inhibitors on oesophageal neuromuscular functions.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20031201

• [One base deletion of the alpha(1,4) galactosyltransferase gene responsible for p phenotype].

  Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 20031201

• Cyclic GMP protein kinase activity is reduced in thyroxine-induced hypertrophic cardiac myocytes.

  Clinical and experimental pharmacology & physiology 20031201

• DNA lesions derived from the site selective oxidation of Guanine by carbonate radical anions.

  Chemical research in toxicology 20031201

• Reduced expression of a novel mu-opioid receptor (MOR) subtype MOR-1B in CXBK mice: implications of MOR-1B in the expression of MOR-mediated responses.

  The European journal of neuroscience 20031201

• Molecular and biochemical analyses of OsRab7, a rice Rab7 homolog.

  Plant & cell physiology 20031201

• Repeated cocaine administration changes the function and subcellular distribution of adenosine A1 receptor in the rat nucleus accumbens.

  Journal of neurochemistry 20031201

• Non-genomic modulation of dopamine release by bisphenol-A in PC12 cells.

  Journal of neurochemistry 20031201

• Synthesis and conformational analysis of a locked analogue of carbovir built on a bicyclo[3.1.0]hex-2-enyl template.

  Nucleosides, nucleotides & nucleic acids 20031201

• Efficacy of methylenecyclopropane analogs of nucleosides against herpesvirus replication in vitro.

  Nucleosides, nucleotides & nucleic acids 20031201

• Lack of mu-opioid receptor-mediated G-protein activation in the spinal cord of mice lacking Exon 1 or Exons 2 and 3 of the MOR-1 gene.

  Journal of pharmacological sciences 20031201

• Guanosine 3',5'-cyclic monophosphate: a tapeworm-secreted signal molecule communicating with the rat host's small intestine.

  The Journal of parasitology 20031201

• Conformational states of the corticotropin releasing factor 1 (CRF1) receptor: detection, and pharmacological evaluation by peptide ligands.

  Peptides 20031201

• Functional properties of Pfr(Tic)amide and BIBP3226 at human neuropeptide FF2 receptors.

  Peptides 20031201

• Defective human MutY phosphorylation exists in colorectal cancer cell lines with wild-type MutY alleles.

  The Journal of biological chemistry 20031128

• Cell-specific behavior of P2X7 receptors in mouse parotid acinar and duct cells.

  The Journal of biological chemistry 20031128

• A novel ergot alkaloid as a 5-HT(1A) inhibitor produced by Dicyma sp.

  Journal of medicinal chemistry 20031120

• Formation of 13C-, 15N-, and 18O-labeled guanidinohydantoin from guanosine oxidation with singlet oxygen. Implications for structure and mechanism.

  Journal of the American Chemical Society 20031119

• Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 3.

  Bioorganic & medicinal chemistry letters 20031117

• Urinary excretion of three nucleic acid oxidation adducts and isoprostane F(2)alpha measured by liquid chromatography-mass spectrometry in smokers, ex-smokers, and nonsmokers.

  Free radical biology & medicine 20031115

• Parallel coiled-coil association of the RhoA-binding domain in Rho-kinase.

  The Journal of biological chemistry 20031114

• Superoxide generation mediated by 8-nitroguanosine, a highly redox-active nucleic acid derivative.

  Biochemical and biophysical research communications 20031114

• Selective binding of monovalent cations to the stacking G-quartet structure formed by guanosine 5'-monophosphate: a solid-state NMR study.

  Journal of the American Chemical Society 20031112

• Pre-steady-state analysis of the nucleoside hydrolase of Trypanosoma vivax. Evidence for half-of-the-sites reactivity and rate-limiting product release.

  Biochemistry 20031111

• Effect of the oxidized guanosine lesions spiroiminodihydantoin and guanidinohydantoin on proofreading by Escherichia coli DNA polymerase I (Klenow fragment) in different sequence contexts.

  Biochemistry 20031111

• Differential regulation of exocytotic fusion and granule-granule fusion in eosinophils by Ca2+ and GTP analogs.

  The Journal of biological chemistry 20031107

• Compound exocytosis and cumulative fusion in eosinophils.

  The Journal of biological chemistry 20031107

• Determination of the catalytic parameters of the N-terminal half of Escherichia coli ribonuclease E and the identification of critical functional groups in RNA substrates.

  The Journal of biological chemistry 20031107

• Anti-mu opioid antiserum against the third external loop of the cloned mu-opioid receptor acts as a mu receptor neutral antagonist.

  Brain research. Molecular brain research 20031106

• 8-Methylguanosine: a powerful Z-DNA stabilizer.

  Journal of the American Chemical Society 20031105

• Physiology and pathophysiology of vascular signaling controlled by guanosine 3',5'-cyclic monophosphate-dependent protein kinase [corrected].

  Circulation 20031104

• Interactions between epithelial nitric oxide signaling and phosphodiesterase activity in Drosophila.

  American journal of physiology. Cell physiology 20031101

• Decrease in intracellular superoxide sensitizes Bcl-2-overexpressing tumor cells to receptor and drug-induced apoptosis independent of the mitochondria.

  Cell death and differentiation 20031101

• Up-regulation of spinal muscarinic receptors and increased antinociceptive effect of intrathecal muscarine in diabetic rats.

  The Journal of pharmacology and experimental therapeutics 20031101

• Ca2+ responses in Chinese hamster ovary-K1 cells demonstrate an atypical pattern of ligand-induced 5-HT1A receptor activation.

  The Journal of pharmacology and experimental therapeutics 20031101

• N-terminal modifications leading to peptide ORL1 partial agonists and antagonists.

  The journal of peptide research : official journal of the American Peptide Society 20031101

• Selective gamma-hydroxybutyric acid receptor ligands increase extracellular glutamate in the hippocampus, but fail to activate G protein and to produce the sedative/hypnotic effect of gamma-hydroxybutyric acid.

  Journal of neurochemistry 20031101

• Guanylyl cyclases, nitric oxide, natriuretic peptides, and airway smooth muscle function.

  American journal of physiology. Lung cellular and molecular physiology 20031101

• G-quartet self-assembly under osmotic pressure: remote control by vesicle shrinking rather than stress.

  Chirality 20031101

• Plasma membrane-associated nucleoside diphosphate kinase (nm23) in the heart is regulated by beta-adrenergic signaling.

  British journal of pharmacology 20031101

• Lidocaine enhances Galphai protein function.

  Anesthesiology 20031101

• The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily.

  European journal of immunology 20031101

• Metabotropic glutamate receptor regulation of neuronal cell death.

  Experimental neurology 20031101

• Mycophenolate mofetil inhibits human Tenon fibroblast proliferation by guanosine depletion.

  The British journal of ophthalmology 20031101

• Basal nitric oxide modulates vascular effects of a peptide activating protease-activated receptor 2.

  Cardiovascular research 20031101

• Functional autoradiography of neuropeptide Y Y1 and Y2 receptor subtypes in rat brain using agonist stimulated [35S]GTPgammaS binding.

  Journal of chemical neuroanatomy 20031101

• Direct evidence for the up-regulation of spinal micro-opioid receptor function after repeated stimulation of kappa-opioid receptors in the mouse.

  The European journal of neuroscience 20031101

• Functional effects of deleting the coiled-coil motif in Escherichia coli elongation factor Ts.

  European journal of biochemistry 20031101

• Low molecular weight G-proteins of rho-family mediate relaxations to bradykinin in porcine coronary arteries.

  Acta pharmacologica Sinica 20031101

• MPP+ induces the endoplasmic reticulum stress response in rabbit brain involving activation of the ATF-6 and NF-kappaB signaling pathways.

  Journal of neuropathology and experimental neurology 20031101

• Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice.

  The European journal of neuroscience 20031101

• Tuberous sclerosis complex: genetics to pathogenesis.

  Pediatric neurology 20031101

• Inhibition of Bacillus subtilis aprE expression by lincomycin at the posttranscriptional level through inhibition of ppGpp synthesis.

  Journal of biochemistry 20031101

• A novel Escherichia coli strain allows functional analysis of guanylate kinase drug resistance and sensitivity.

  Analytical biochemistry 20031101

• [Studies on chemical constituents of the mycelia from fermented culture of Flammulina velutipes].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20031101

• Use of 13C as an indirect tag in 15N specifically labeled nucleosides. Syntheses of [8-13C-1,7,NH2-15N3]adenosine, -guanosine, and their deoxy analogues.

  The Journal of organic chemistry 20031031

• Labile iron pool: the main determinant of cellular response to oxidative stress.

  Mutation research 20031029

• Site-specific DNA transesterification by vaccinia topoisomerase: effects of benzo[alpha]pyrene-dA, 8-oxoguanine, 8-oxoadenine and 2-aminopurine modifications.

  The Journal of biological chemistry 20031024

• Dimers of class A G protein-coupled receptors function via agonist-mediated trans-activation of associated G proteins.

  The Journal of biological chemistry 20031024

• Functional annotation of the putative orphan Caenorhabditis elegans G-protein-coupled receptor C10C6.2 as a FLP15 peptide receptor.

  The Journal of biological chemistry 20031024

• Identification of a hexapeptide binding region in the nociceptin (ORL1) receptor by photo-affinity labelling with Ac-Arg-Bpa-Tyr-Arg-Trp-Arg-NH2.

  Biochemical and biophysical research communications 20031024

• Helix 8 of the leukotriene B4 receptor is required for the conformational change to the low affinity state after G-protein activation.

  The Journal of biological chemistry 20031017

• CP-481,715, a potent and selective CCR1 antagonist with potential therapeutic implications for inflammatory diseases.

  The Journal of biological chemistry 20031017

• Evidence for an intracellular ADP-ribosyl cyclase/NAD+-glycohydrolase in brain from CD38-deficient mice.

  The Journal of biological chemistry 20031017

• Cytosolic Arl2 is complexed with cofactor D and protein phosphatase 2A.

  The Journal of biological chemistry 20031017

• Selective fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene by nucleotides.

  Organic letters 20031016

• Macrocyclic amines as catalysts of the hydrolysis of the triphosphate bridge of the mRNA 5'-cap structure.

  Organic & biomolecular chemistry 20031007

• Synthesis of S6-(2,4-dinitrophenyl)-6-thioguanosine phosphoramidite and its incorporation into oligoribonucleotides.

  Bioorganic & medicinal chemistry letters 20031006

• Progressive alterations in global and GC-rich DNA methylation during tumorigenesis.

  Toxicological sciences : an official journal of the Society of Toxicology 20031001

• GTP gamma S increases Nav1.8 current in small-diameter dorsal root ganglia neurons.

  Experimental brain research 20031001

• Evidence for multiple distinctly localized adenylyl cyclase isoforms in mammalian spermatozoa.

  Molecular reproduction and development 20031001

• Methods for the design and analysis of oligodeoxynucleotide-based DNA (cytosine-5) methyltransferase inhibitors.

  Analytical biochemistry 20031001

• Biochemical evidence for a P2Y-like receptor in Tetrahymena thermophila.

  Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20031001

• Pharmacological characterization and identification of amino acids involved in the positive modulation of metabotropic glutamate receptor subtype 2.

  Molecular pharmacology 20031001

• Ki16425, a subtype-selective antagonist for EDG-family lysophosphatidic acid receptors.

  Molecular pharmacology 20031001

• Contribution of active site residues to the activity and thermal stability of ribonuclease Sa.

  Protein science : a publication of the Protein Society 20031001

• Involvement of rpoS in the survival of Escherichia coli in the viable but non-culturable state.

  Environmental microbiology 20031001

• Insulin and lysophosphatidylcholine synergistically stimulate NO-dependent cGMP production in human endothelial cells.

  Diabetic medicine : a journal of the British Diabetic Association 20031001

• Identification of a ribavirin-resistant NS5B mutation of hepatitis C virus during ribavirin monotherapy.

  Hepatology (Baltimore, Md.) 20031001

• Comparative analysis of functional assays for characterization of agonist ligands at G protein-coupled receptors.

  Journal of biomolecular screening 20031001

• Inhibition of the group I ribozyme splicing by NADP+.

  Molecular and cellular biochemistry 20031001

• Implication of adenosine 3',5'-cyclic monophosphate, guanosine 3',5'-cyclic monophosphate, adenosine 5'-mono-, di-, and triphosphate and fructose-2,6-bisphosphate in the regulation of the glycolytic pathway in relation to the gametogenic cycle in the mussel mytilus galloprovincialis Lmk.

  Molecular and cellular biochemistry 20031001

• G3139 (oblimersen) may inhibit prostate cancer cell growth in a partially bis-CpG-dependent non-antisense manner.

  Molecular cancer therapeutics 20031001

• Expression of nitric oxide synthase isoforms in the human placenta is not altered by labor.

  Endocrine journal 20031001

• Cannabinoid receptor and WIN 55 212-2-stimulated [35S]-GTPgammaS binding in the brain of mu-, delta- and kappa-opioid receptor knockout mice.

  The European journal of neuroscience 20031001

• Hypocretin-1 causes G protein activation and increases ACh release in rat pons.

  The European journal of neuroscience 20031001

• Review of the antiproliferative properties of mycophenolate mofetil in non-immune cells.

  International journal of clinical pharmacology and therapeutics 20031001

• Development of displacement binding and GTPgammaS scintillation proximity assays for the identification of antagonists of the micro-opioid receptor.

  Assay and drug development technologies 20031001

• Neurodegeneration in striatum induced by the mitochondrial toxin 3-nitropropionic acid: role of matrix metalloproteinase-9 in early blood-brain barrier disruption?

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030924

• Constitutive activation of CCR5 and CCR2 induced by conformational changes in the conserved TXP motif in transmembrane helix 2.

  The Journal of biological chemistry 20030919

• Oxidized human neuroglobin acts as a heterotrimeric Galpha protein guanine nucleotide dissociation inhibitor.

  The Journal of biological chemistry 20030919

• Role of ADP-ribosylation factor 6 (ARF6) in gastric acid secretion.

  The Journal of biological chemistry 20030919

• Essential role of histidine 84 in elongation factor Tu for the chemical step of GTP hydrolysis on the ribosome.

  Journal of molecular biology 20030919

• The role of cGMP in the regulation of rabbit airway ciliary beat frequency.

  The Journal of physiology 20030915

• Involvement of NMDA receptors and L-arginine-nitric oxide pathway in the antidepressant-like effects of zinc in mice.

  Behavioural brain research 20030915

• Equilibrative nucleoside transporter family members from Leishmania donovani are electrogenic proton symporters.

  The Journal of biological chemistry 20030912

• Lipophilic G-quadruplexes are self-assembled ion pair receptors, and the bound anion modulates the kinetic stability of these complexes.

  Journal of the American Chemical Society 20030910

• Amyloid precursor protein carboxy-terminal fragments modulate G-proteins and adenylate cyclase activity in Alzheimer's disease brain.

  Brain research. Molecular brain research 20030910

• Gene transfer of human guanosine 5'-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension.

  Circulation 20030909

• Differential activation of 'social' and 'solitary' variants of the Caenorhabditis elegans G protein-coupled receptor NPR-1 by its cognate ligand AF9.

  The Journal of biological chemistry 20030905

• Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions.

  Cell 20030905

• Protection of the amino group of adenosine and guanosine derivatives by elaboration into a 2,5-dimethylpyrrole moiety.

  Organic letters 20030904

• Group II mGlu receptor activation suppresses norepinephrine release in the ventral hippocampus and locomotor responses to acute ketamine challenge.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030901

• Functional coupling between heterologously expressed dopamine D(2) receptors and KCNQ channels.

  Pflugers Archiv : European journal of physiology 20030901

• Inhibition of GTP-dependent vesicle trafficking impairs internalization of plasmalemmal eNOS and cellular nitric oxide production.

  Journal of cell science 20030901

• Somatic embryogenesis in loblolly pine (Pinus taeda L.): improving culture initiation with abscisic acid and silver nitrate.

  Plant cell reports 20030901

• Hg2+ signaling in trout hepatoma (RTH-149) cells: involvement of Ca2+-induced Ca2+ release.

  Cell calcium 20030901

• Activation by N-acetyl-L-aspartate of acutely dissociated hippocampal neurons in rats via metabotropic glutamate receptors.

  Epilepsia 20030901

• Comparison of hippocampal G protein activation by 5-HT(1A) receptor agonists and the atypical antipsychotics clozapine and S16924.

  Naunyn-Schmiedeberg's archives of pharmacology 20030901

• Purine and pyrimidine metabolites in children's urine.

  Clinica chimica acta; international journal of clinical chemistry 20030901

• The blockade of formyl peptide-induced respiratory burst by 2',5'-dihydroxy-2-furfurylchalcone involves phospholipase D signaling in neutrophils.

  Naunyn-Schmiedeberg's archives of pharmacology 20030901

• Charge distribution in 7-methylguanine regarding cation-pi interaction with protein factor eIF4E.

  Biophysical journal 20030901

• L-arginine-induced relaxation of the internal anal sphincter is not mediated by nitric oxide.

  The British journal of surgery 20030901

• The novel nucleoside transport system exhibited by NB4 cells, csg, transports deoxyguanosine analogues, including ara-G.

  Biochemical pharmacology 20030901

• Functional calcium coupling with the human metabotropic glutamate receptor subtypes 2 and 4 by stable co-expression with a calcium pathway facilitating G-protein chimera in Chinese hamster ovary cells.

  Biochemical pharmacology 20030901

• Sevoflurane inhibits guanosine 5'-[gamma-thio]triphosphate-stimulated, Rho/Rho-kinase-mediated contraction of isolated rat aortic smooth muscle.

  Anesthesiology 20030901

• Expression of EGFP-amino-tagged human mu opioid receptor in Drosophila Schneider 2 cells: a potential expression system for large-scale production of G-protein coupled receptors.

  Protein expression and purification 20030901

• Partial agonist behaviour depends upon the level of nociceptin/orphanin FQ receptor expression: studies using the ecdysone-inducible mammalian expression system.

  British journal of pharmacology 20030901

• Molecular mechanisms of ligand-receptor interactions in transmembrane domain V of the alpha2A-adrenoceptor.

  British journal of pharmacology 20030901

• An insight into the phenomena involved in a multiple-function stationary phase for the capillary electrochromatographic separation of 2'-, 3'-, and 5'-monophosphorylated nucleoside isomers.

  Electrophoresis 20030901

• Current and future therapy for chronic hepatitis C virus liver disease.

  Current drug targets. Infectious disorders 20030901

• Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines.

  Journal of neuro-oncology 20030901

• Photodynamic activity of monocationic and non-charged methoxyphenylporphyrin derivatives in homogeneous and biological media.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20030901

• Characterization of YopT effects on Rho GTPases in Yersinia enterocolitica-infected cells.

  The Journal of biological chemistry 20030829

• Functional analysis of an inosine-guanosine transporter from Leishmania donovani. The role of conserved residues, aspartate 389 and arginine 393.

  The Journal of biological chemistry 20030829

• Selective interactions between helix VIII of the human mu-opioid receptors and the C terminus of periplakin disrupt G protein activation.

  The Journal of biological chemistry 20030829

• Antioxidant compounds from the leaves of Peucedanum japonicum thunb.

  Journal of agricultural and food chemistry 20030827

• Reduced G(i) and G(o) protein function in the rat nucleus accumbens attenuates sensorimotor gating deficits.

  Brain research 20030822

• Efficient one-step Suzuki arylation of unprotected halonucleosides, using water-soluble palladium catalysts.

  The Journal of organic chemistry 20030822

• The design and synthesis of guanosine compounds with in vitro activity against the colon cancer cell line SW480: non-taxane derived mimics of taxol?

  Bioorganic & medicinal chemistry letters 20030818

• Three kinds of current in response to substance P in bullfrog DRG neurons.

  Brain research 20030815

• The hydantoin lesions formed from oxidation of 7,8-dihydro-8-oxoguanine are potent sources of replication errors in vivo.

  Biochemistry 20030812

• Hyaluronan-mediated CD44 interaction with RhoGEF and Rho kinase promotes Grb2-associated binder-1 phosphorylation and phosphatidylinositol 3-kinase signaling leading to cytokine (macrophage-colony stimulating factor) production and breast tumor progression.

  The Journal of biological chemistry 20030808

• Agonist-induced formation of opioid receptor-G protein-coupled receptor kinase (GRK)-G beta gamma complex on membrane is required for GRK2 function in vivo.

  The Journal of biological chemistry 20030808

• Sequence specific DNA binding of Ets-1 transcription factor: molecular dynamics study on the Ets domain--DNA complexes.

  Journal of molecular biology 20030808

• Selectivity of purine alkylation by a quinone methide. Kinetic or thermodynamic control?

  The Journal of organic chemistry 20030808

• A putative consensus sequence for the nucleotide-binding site of annexin A6.

  Biochemistry 20030805

• Light-mediated activation of Rac-1 in photoreceptor outer segments.

  Current biology : CB 20030805

• Characterization of the binding of [3H][Dmt1]H-Dmt-D-Arg-Phe-Lys-NH2, a highly potent opioid peptide.

  The Journal of pharmacology and experimental therapeutics 20030801

• Diurnal variation in the renal excretion of modified RNA catabolites in humans.

  Clinical science (London, England : 1979) 20030801

• Chronic fluoxetine differentially affects 5-hydroxytryptamine (2A) receptor signaling in frontal cortex, oxytocin- and corticotropin-releasing factor-containing neurons in rat paraventricular nucleus.

  The Journal of pharmacology and experimental therapeutics 20030801

• Functional melatonin receptors in rat ovaries at various stages of the estrous cycle.

  The Journal of pharmacology and experimental therapeutics 20030801

• IIGP1, an interferon-gamma-inducible 47-kDa GTPase of the mouse, showing cooperative enzymatic activity and GTP-dependent multimerization.

  The Journal of biological chemistry 20030801

• Entrapment of Rho ADP-ribosylated by Clostridium botulinum C3 exoenzyme in the Rho-guanine nucleotide dissociation inhibitor-1 complex.

  The Journal of biological chemistry 20030801

• Dissociation of cGMP accumulation and relaxation in myometrial smooth muscle: effects of S-nitroso-N-acetylpenicillamine and 3-morpholinosyndonimine.

  Cellular signalling 20030801

• Testosterone stimulates intracellular calcium release and mitogen-activated protein kinases via a G protein-coupled receptor in skeletal muscle cells.

  Endocrinology 20030801

• Urinary 8-hydroxydeoxyguanosine and its analogs as DNA marker of oxidative stress: development of an ELISA and measurement in both bladder and prostate cancers.

  Clinica chimica acta; international journal of clinical chemistry 20030801

• Painful inflammation-induced increase in mu-opioid receptor binding and G-protein coupling in primary afferent neurons.

  Molecular pharmacology 20030801

• Differential involvement of intracellular domains of the rat NTS1 neurotensin receptor in coupling to G proteins: a molecular basis for agonist-directed trafficking of receptor stimulus.

  Molecular pharmacology 20030801

• Tiotidine, a histamine H2 receptor inverse agonist that binds with high affinity to an inactive G-protein-coupled form of the receptor. Experimental support for the cubic ternary complex model.

  Molecular pharmacology 20030801

• Use of nucleotide analogs by class I and class II CCA-adding enzymes (tRNA nucleotidyltransferase): deciphering the basis for nucleotide selection.

  RNA (New York, N.Y.) 20030801

• G-protein activation decreases isoflurane inhibition of N-type Ba2+ currents.

  Anesthesiology 20030801

• Pathways for the regulation of interferon-gamma-inducible genes by iron in human monocytic cells.

  Journal of leukocyte biology 20030801

• Transduction of the liver with activated Akt normalizes portal pressure in cirrhotic rats.

  Gastroenterology 20030801

• Pressure effects on the GTPase activity of brain membrane G proteins of deep-living marine fishes.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030801

• Lignan and megastigmane glycosides from Sauropus androgynus.

  Phytochemistry 20030801

• Expression and G-protein coupling of mu-opioid receptors in the spinal cord and dorsal root ganglia of polyarthritic rats.

  Neuropeptides 20030801

• Phosphodiesterases in the vascular system.

  Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20030801

• Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression.

  Nature 20030731

• Identification and characterisation of high affinity nucleoside and nucleobase transporters in Toxoplasma gondii.

  International journal for parasitology 20030730

• Novel guanosine-cytidine dinucleoside that self-assembles into a trimeric supramolecule.

  Organic letters 20030724

• Advances Toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT(1A) receptor antagonism/SSRI activities. Part 2.

  Bioorganic & medicinal chemistry letters 20030721

• Evidence for the involvement of G-proteins in the generation of the slow poststimulus afterdepolarisation (sADP) induced by muscarinic receptor activation in rat olfactory cortical neurones in vitro.

  Brain research 20030718

• Glutamate receptors in the terminal nerve gonadotropin-releasing hormone neurons of the dwarf gourami (teleost).

  Neuroscience letters 20030717

• l-2',3'-Didehydro-2',3'-dideoxy-3'-fluoronucleosides: synthesis, anti-HIV activity, chemical and enzymatic stability, and mechanism of resistance.

  Journal of medicinal chemistry 20030717

• Non-hydrolyzable analog of GTP induces activity of Na+ channels via disassembly of cortical actin cytoskeleton.

  FEBS letters 20030717

• Excitatory effects of orexin-A on nucleus tractus solitarius neurons are mediated by phospholipase C and protein kinase C.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030716

• Role of tissue transglutaminase in GTP depletion-induced apoptosis of insulin-secreting (HIT-T15) cells.

  Biochemical pharmacology 20030715

• Differential translation of TOP mRNAs in rapamycin-treated human B lymphocytes.

  Biochimica et biophysica acta 20030709

• Cholesterol-dependent association of caveolin-1 with the transducin alpha subunit in bovine photoreceptor rod outer segments: disruption by cyclodextrin and guanosine 5'-O-(3-thiotriphosphate).

  Biochemistry 20030708

• The myristoylated amino terminus of Galpha(i)(1) plays a critical role in the structure and function of Galpha(i)(1) subunits in solution.

  Biochemistry 20030708

• Influence of cytosolic AGS3 on receptor--G protein coupling.

  Biochemistry 20030708

• Platinum(II)-based coordination compounds as nucleic acid labeling reagents: synthesis, reactivity, and applications in hybridization assays.

  Chembiochem : a European journal of chemical biology 20030707

• Curing of foot-and-mouth disease virus from persistently infected cells by ribavirin involves enhanced mutagenesis.

  Virology 20030705

• Chronically administered guanosine is anticonvulsant, amnesic and anxiolytic in mice.

  Brain research 20030704

• Synthesis and characterization of NESS 0327: a novel putative antagonist of the CB1 cannabinoid receptor.

  The Journal of pharmacology and experimental therapeutics 20030701

• Studies of micro-, kappa-, and delta-opioid receptor density and G protein activation in the cortex and thalamus of monkeys.

  The Journal of pharmacology and experimental therapeutics 20030701

• Activation of phosphoinositide 3-kinase by D2 receptor prevents apoptosis in dopaminergic cell lines.

  The Biochemical journal 20030701

• beta-Funaltrexamine, a gauge for the recognition site of wildtype and mutant H297Q mu-opioid receptors.

  Synapse (New York, N.Y.) 20030701

• Arsenate reduction in human erythrocytes and rats--testing the role of purine nucleoside phosphorylase.

  Toxicological sciences : an official journal of the Society of Toxicology 20030701

• Regulation of early endocytic vesicle motility and fission in a reconstituted system.

  Journal of cell science 20030701

• 2-Alkylthio-substituted platelet P2Y12 receptor antagonists reveal pharmacological identity between the rat brain Gi-linked ADP receptors and P2Y12.

  Neuropharmacology 20030701

• Pharmacological characterization of the human P2Y13 receptor.

  Molecular pharmacology 20030701

• Effect of halothane on the guanosine 5' triphosphate binding activity of G-protein alphai subunits.

  Anesthesiology 20030701

• The avilamycin resistance determinants AviRa and AviRb methylate 23S rRNA at the guanosine 2535 base and the uridine 2479 ribose.

  Molecular microbiology 20030701

• Binding and GTPgammaS autoradiographic analysis of preproorphanin precursor peptide products at the ORL1 and opioid receptors.

  Journal of chemical neuroanatomy 20030701

• Photochemical cross-linking of Escherichia coli Fpg protein to DNA duplexes containing phenyl(trifluoromethyl)diazirine groups.

  European journal of biochemistry 20030701

• Regulation of eosinophil apoptosis by nitric oxide: Role of c-Jun-N-terminal kinase and signal transducer and activator of transcription 5.

  The Journal of allergy and clinical immunology 20030701

• Estrogen-dependent alterations in D2/D3-induced G protein activation in cocaine-sensitized female rats.

  Journal of neurochemistry 20030701

• The effect of nitric oxide on the permeability of nasal epithelial cells from healthy and asthmatic donors.

  Medical science monitor : international medical journal of experimental and clinical research 20030701

• Efficacy of 8-bromoguanosine against murine cutaneous leishmaniasis induced with Leishmania amazonensis.

  Chemotherapy 20030701

• Binding characteristics of [3H]14-methoxymetopon, a high affinity mu-opioid receptor agonist.

  The European journal of neuroscience 20030701

• Control of rRNA expression by small molecules is dynamic and nonredundant.

  Molecular cell 20030701

• Increased endothelin: nitric oxide ratio is associated with erythropoietin-induced hypertension in hemodialysis patients.

  Renal failure 20030701

• ['Magic spot' synthase in chloroplasts].

  Seikagaku. The Journal of Japanese Biochemical Society 20030701

• Soluble guanylyl cyclase: physiological role as an NO receptor and the potential molecular target for therapeutic application.

  Clinical chemistry and laboratory medicine 20030701

• Cloning, heterologous expression, and in situ characterization of the first high affinity nucleobase transporter from a protozoan.

  The Journal of biological chemistry 20030627

• Co-expression of the beta2-adrenoceptor and dopamine D1-receptor with Gsalpha proteins in Sf9 insect cells: limitations in comparison with fusion proteins.

  Biochimica et biophysica acta 20030627

• Signal transduction in the visual cascade involves specific lipid-protein interactions.

  The Journal of biological chemistry 20030620

• Pharmacological analysis of a dopamine D(2Short):G(alphao) fusion protein expressed in Sf9 cells.

  FEBS letters 20030619

• Direct detection of potassium cations bound to G-quadruplex structures by solid-state 39K NMR at 19.6 T.

  Journal of the American Chemical Society 20030618

• Unexpected inhibition of S-adenosyl-L-homocysteine hydrolase by a guanosine nucleoside.

  Bioorganic & medicinal chemistry letters 20030616

• Synthesis and characterization of platinum diimine bis(acetylide) complexes containing easily derivatizable aryl acetylide ligands.

  Inorganic chemistry 20030616

• Induction of apoptosis in IL-3-dependent hematopoietic cell lines by guanine nucleotide depletion.

  Blood 20030615

• Nongenomic glucocorticoid inhibition via endocannabinoid release in the hypothalamus: a fast feedback mechanism.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030615

• Crystallographic characterization of an exocyclic DNA adduct: 3,N4-etheno-2'-deoxycytidine in the dodecamer 5'-CGCGAATTepsilonCGCG-3'.

  Journal of molecular biology 20030613

• Distinct effects of amantadine and memantine on dopaminergic transmission in the rat striatum.

  Neuroscience letters 20030612

• Expression and modulation of an invertebrate presynaptic calcium channel alpha1 subunit homolog.

  The Journal of biological chemistry 20030606

• Activation of in situ tissue transglutaminase by intracellular reactive oxygen species.

  Biochemical and biophysical research communications 20030606

• The effect of ribavirin and IMPDH inhibitors on hepatitis C virus subgenomic replicon RNA.

  Virology 20030605

• Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 1.

  Bioorganic & medicinal chemistry letters 20030602

• Acid-base and metal ion binding properties of guanylyl(3'-->5')guanosine (GpG-) and 2'-deoxyguanylyl(3'-->5')-2'-deoxyguanosine [d(GpG)-] in aqueous solution.

  Inorganic chemistry 20030602

• Crystal structure of tRNA(m1G37)methyltransferase: insights into tRNA recognition.

  The EMBO journal 20030602

• Two novel and selective nonimidazole histamine H3 receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects.

  The Journal of pharmacology and experimental therapeutics 20030601

• Prolactin releasing peptide has high affinity and efficacy at neuropeptide FF2 receptors.

  The Journal of pharmacology and experimental therapeutics 20030601

• Dissimilar pharmacological responses by a new series of imidazoline derivatives at precoupled and ligand-activated alpha 2A-adrenoceptor states: evidence for effector pathway-dependent differential antagonism.

  The Journal of pharmacology and experimental therapeutics 20030601

• Dopamine-mediated inhibition of renal Na,K-ATPase is reduced by insulin.

  Hypertension (Dallas, Tex. : 1979) 20030601

• Native somatostatin sst2 and sst5 receptors functionally coupled to Gi/o-protein, but not to the serum response element in AtT-20 mouse tumour corticotrophs.

  Naunyn-Schmiedeberg's archives of pharmacology 20030601

• Ethanol consumption and serotonin-1A (5-HT1A) receptor function in heterozygous BDNF (+/-) mice.

  Journal of neurochemistry 20030601

• Heterologous mu-opioid receptor adaptation by repeated stimulation of kappa-opioid receptor: up-regulation of G-protein activation and antinociception.

  Journal of neurochemistry 20030601

• Established and emerging fluorescence-based assays for G-protein function: heterotrimeric G-protein alpha subunits and regulator of G-protein signaling (RGS) proteins.

  Combinatorial chemistry & high throughput screening 20030601

• Induction of antioxidative and antiapoptotic thioredoxin supports neuroprotective hypothesis of estrogen.

  Endocrine 20030601

• Control of signalling efficacy by palmitoylation of the rat Y1 receptor.

  British journal of pharmacology 20030601

• Functional characterization of a H+/nucleoside co-transporter (CaCNT) from Candida albicans, a fungal member of the concentrative nucleoside transporter (CNT) family of membrane proteins.

  Yeast (Chichester, England) 20030601

• SB-656104-A, a novel selective 5-HT7 receptor antagonist, modulates REM sleep in rats.

  British journal of pharmacology 20030601

• Gabapentin blocks L-type and P/Q-type Ca2+ channels involved in depolarization-stimulated nitric oxide synthase activity in primary cultures of neurons from mouse cerebral cortex.

  Pharmaceutical research 20030601

• Tumor-inhibiting platinum(II) complexes with aminoalcohol ligands: comparison of the mode of action by capillary electrophoresis and electrospray ionization-mass spectrometry.

  Electrophoresis 20030601

• Inactivation of platelet glycoprotein IIb/IIIa receptor by nitric oxide donor 3-morpholino-sydnonimine.

  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20030601

• Melatonin exerts an antidepressant-like effect in the tail suspension test in mice: evidence for involvement of N-methyl-D-aspartate receptors and the L-arginine-nitric oxide pathway.

  Neuroscience letters 20030529

• Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase. Steady state and pre-steady state kinetic analyses.

  The Journal of biological chemistry 20030523

• Structure-activity relationships of dynorphin a analogues modified in the address sequence.

  Journal of medicinal chemistry 20030522

• Ionic states of substrates and transition state analogues at the catalytic sites of N-ribosyltransferases.

  Biochemistry 20030520

• Novel synthesis of 2'-O-methylguanosine.

  Bioorganic & medicinal chemistry letters 20030519

• Delayed expression of apoptosis in human lymphoma cells undergoing low-dose taxol-induced mitotic stress.

  British journal of cancer 20030519

• Serine 338 phosphorylation is dispensable for activation of c-Raf1.

  The Journal of biological chemistry 20030516

• Poly(ADP-ribose) polymerase-1 (PARP-1) is required in murine cell lines for base excision repair of oxidative DNA damage in the absence of DNA polymerase beta.

  The Journal of biological chemistry 20030516

• Extracellular conversion of guanine-based purines to guanosine specifically enhances astrocyte glutamate uptake.

  Brain research 20030516

• Ontogeny of GABA(B) receptor subunit expression and function in the rat spinal cord.

  Brain research 20030516

• Ca2+/calmodulin binds and dissociates K-RasB from membrane.

  Biochemical and biophysical research communications 20030516

• Effect of strain and sex on mu opioid receptor-mediated G-protein activation in rat brain.

  Brain research bulletin 20030515

• Crystal structures of the ribonuclease MC1 mutants N71T and N71S in complex with 5'-GMP: structural basis for alterations in substrate specificity.

  Biochemistry 20030513

• Positioning of mRNA codons with respect to 18S rRNA at the P and E sites of human ribosome.

  Biochimica et biophysica acta 20030513

• Recombinant antibodies to the small GTPase Rab6 as conformation sensors.

  Science (New York, N.Y.) 20030509

• Toward novel DNA binding metal complexes: structure and basic kinetic data of [M(9MeG)2(CH3OH)(CO)3]+(M = 99Tc, Re).

  Inorganic chemistry 20030505

• Promiscuous coupling at receptor-Galpha fusion proteins. The receptor of one covalent complex interacts with the alpha-subunit of another.

  The Journal of biological chemistry 20030502

• The vesicular monoamine content regulates VMAT2 activity through Galphaq in mouse platelets. Evidence for autoregulation of vesicular transmitter uptake.

  The Journal of biological chemistry 20030502

• Induction of vasorelaxation through activation of nitric oxide synthase in endothelial cells by brazilin.

  European journal of pharmacology 20030502

• A GC-box within the proximal promoter region of the rat cathepsin L gene activates transcription in Sertoli cells of sexually mature rats.

  Biology of reproduction 20030501

• Endogenous opioid peptides contribute to antinociceptive potency of intrathecal [Dmt1]DALDA.

  The Journal of pharmacology and experimental therapeutics 20030501

• Differential regulation of the human kappa opioid receptor by agonists: etorphine and levorphanol reduced dynorphin A- and U50,488H-induced internalization and phosphorylation.

  The Journal of pharmacology and experimental therapeutics 20030501

• An unusual form of the association binding kinetics of N-[3H]methylscopolamine to the split muscarinic M2trunk/M2tail receptor.

  The Journal of pharmacology and experimental therapeutics 20030501

• Functional differences between human formyl peptide receptor isoforms 26, 98, and G6.

  Naunyn-Schmiedeberg's archives of pharmacology 20030501

• Mycophenolic acid inhibits activation of inducible nitric oxide synthase in rodent fibroblasts.

  Clinical and experimental immunology 20030501

• Identification of the yeast gene encoding the tRNA m1G methyltransferase responsible for modification at position 9.

  RNA (New York, N.Y.) 20030501

• Characterization and maturational differences of melatonin binding sites in the masu salmon brain.

  General and comparative endocrinology 20030501

• The lectin jacalin induces phosphorylation of ERK and JNK in CD4+ T cells.

  Journal of leukocyte biology 20030501

• Important amino acids for the function of the human MT1 melatonin receptor.

  Biochemical pharmacology 20030501

• Antiguanosine antibodies in murine and human lupus have the internal image of G-binding proteins.

  The Journal of rheumatology 20030501

• Slow inhibition of N-type calcium channels with GTP gamma S reflects the basal G protein-GDP turnover rate.

  Pflugers Archiv : European journal of physiology 20030501

• Ontogenetic development of cannabinoid receptor expression and signal transduction functionality in the human brain.

  The European journal of neuroscience 20030501

• Dihydroergotamine and its metabolite, 8'-hydroxy-dihydroergotamine, as 5-HT1A receptor agonists in the rat brain.

  British journal of pharmacology 20030501

• Involvement of H2O2 in superoxide-dismutase-induced enhancement of endothelium-dependent relaxation in rabbit mesenteric resistance artery.

  British journal of pharmacology 20030501

• Two lead drug designs based on chloramphenicol as the parent structure, which express alkylation activity with potential for clinical applications.

  The Journal of pharmacy and pharmacology 20030501

• Role of ascorbic acid in the modulation of inhibition of platelet aggregation by polymorphonuclear leukocytes.

  Thrombosis research 20030501

• Neuroprotective actions of Selegiline in inhibiting 1-methyl, 4-phenyl, pyridinium ion (MPP+)-induced apoptosis in SK-N-SH neurons.

  Journal of neurocytology 20030501

• Carcinogenic semicarbazide induces sequence-specific DNA damage through the generation of reactive oxygen species and the derived organic radicals.

  Mutation research 20030420

• Latrunculin B or ATP depletion induces cofilin-dependent translocation of actin into nuclei of mast cells.

  The Journal of biological chemistry 20030418

• GTP-induced tetrodotoxin-resistant Na+ current regulates excitability in mouse and rat small diameter sensory neurones.

  The Journal of physiology 20030415

• GABA transmission in the nucleus accumbens is altered after withdrawal from repeated cocaine.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415

• 2'(3')-O-(N-methylanthraniloyl)-substituted GTP analogs: a novel class of potent competitive adenylyl cyclase inhibitors.

  The Journal of biological chemistry 20030411

• Distinct regulation of expressed calcium channels 2.3 in Xenopus oocytes by direct or indirect activation of protein kinase C.

  Brain research 20030411

• Identification of a phosphothionate analogue of lysophosphatidic acid (LPA) as a selective agonist of the LPA3 receptor.

  The Journal of biological chemistry 20030404

• ATP modulation of sodium currents in rat dorsal root ganglion neurons.

  Brain research 20030404

• Monomeric complex of human orphan estrogen related receptor-2 with DNA: a pseudo-dimer interface mediates extended half-site recognition.

  Journal of molecular biology 20030404

• Effects of AICAR and exercise on insulin-stimulated glucose uptake, signaling, and GLUT-4 content in rat muscles.

  Journal of applied physiology (Bethesda, Md. : 1985) 20030401

• delta-Opioid receptors exhibit high efficiency when activating trimeric G proteins in membrane domains.

  Journal of neurochemistry 20030401

• Behavioural and gene transcription alterations induced by spontaneous cannabinoid withdrawal in mice.

  Journal of neurochemistry 20030401

• Sphingosine-1-phosphate and its potentially paradoxical effects on critical parameters of cutaneous wound healing.

  The Journal of investigative dermatology 20030401

• Differential regulation of GABA B receptor subunit expression and function.

  The Journal of pharmacology and experimental therapeutics 20030401

• Inhibition of human immunodeficiency virus 1 replication in vitro by a self-stabilized oligonucleotide with 2'-O-methyl-guanosine-uridine quadruplex motifs.

  The Journal of antimicrobial chemotherapy 20030401

• Dual effects of hexanol and halothane on the regulation of calcium sensitivity in airway smooth muscle.

  Anesthesiology 20030401

• Effects of D3.49A, R3.50A, and A6.34E mutations on ligand binding and activation of the cannabinoid-2 (CB2) receptor.

  Biochemical pharmacology 20030401

• Pharmacological characterisation of a cell line expressing GABA B1b and GABA B2 receptor subunits.

  Biochemical pharmacology 20030401

• Interaction of the D2short dopamine receptor with G proteins: analysis of receptor/G protein selectivity.

  Biochemical pharmacology 20030401

• DNA damage and repair system in spinal cord ischemia.

  Journal of vascular surgery 20030401

• Purification and characterization of 5'-methylthioadenosine phosphorylase from the hyperthermophilic archaeon Pyrococcus furiosus: substrate specificity and primary structure analysis.

  Extremophiles : life under extreme conditions 20030401

• Uncoupling of 5-HT1A receptors in the brain by estrogens: regional variations in antagonism by ICI 182,780.

  Neuropharmacology 20030401

• SKF83959 selectively regulates phosphatidylinositol-linked D1 dopamine receptors in rat brain.

  Journal of neurochemistry 20030401

• Arsenic-induced dysfunction in relaxation of blood vessels.

  Environmental health perspectives 20030401

• Covalent binding of leukotriene A4 to DNA and RNA.

  Chemical research in toxicology 20030401

• Control of rRNA expression in Escherichia coli.

  Current opinion in microbiology 20030401

• Mutations of F110 and C126 of the formyl peptide receptor interfere with G-protein coupling and chemotaxis.

  Journal of periodontology 20030401

• Exhaled NO and plasma cGMP increase after endotoxin infusion in healthy volunteers.

  The European respiratory journal 20030401

• The purine nucleoside cycle in cell-free extracts of rat brain: evidence for the occurrence of an inosine and a guanosine cycle with distinct metabolic roles.

  Cellular and molecular life sciences : CMLS 20030401

• A fully automated [35S]GTPgammaS scintillation proximity assay for the high-throughput screening of Gi-linked G protein-coupled receptors.

  Assay and drug development technologies 20030401

• The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.

  The Journal of biological chemistry 20030328

• Active transducin alpha subunit carries PDE6 to detergent-resistant membranes in rod photoreceptor outer segments.

  Biochemical and biophysical research communications 20030328

• Molecular identification of nicotinic acid receptor.

  Biochemical and biophysical research communications 20030328

• Subject-regulated dosing alters morphine self-administration behavior and morphine-stimulated [35S]GTPgammaS binding.

  Synapse (New York, N.Y.) 20030315

• A G protein-coupled receptor responsive to bile acids.

  The Journal of biological chemistry 20030314

• Endogenous RGS protein action modulates mu-opioid signaling through Galphao. Effects on adenylyl cyclase, extracellular signal-regulated kinases, and intracellular calcium pathways.

  The Journal of biological chemistry 20030314

• GDP affinity and order state of the catalytic site are critical for function of xanthine nucleotide-selective Galphas proteins.

  The Journal of biological chemistry 20030307

• Design and synthesis of 3-phenyl tetrahydronaphthalenic derivatives as new selective MT2 melatoninergic ligands.

  Bioorganic & medicinal chemistry 20030306

• Unpredictable stereochemical preferences for mu opioid receptor activity in an exhaustively stereodiversified library of 1,4-enediols.

  Organic letters 20030306

• Restricting the conformational heterogeneity of RNA by specific incorporation of 8-bromoguanosine.

  Journal of the American Chemical Society 20030305

• Differential cholinergic activation of G proteins in rat and mouse brainstem: relevance for sleep and nociception.

  The Journal of comparative neurology 20030303

• Cardiac outflow of amino acids and purines during myocardial ischemia and reperfusion.

  Journal of applied physiology (Bethesda, Md. : 1985) 20030301

• The small GTPase RhoA has greater expression in small cell lung carcinoma than in non-small cell lung carcinoma and contributes to their unique morphologies.

  International journal of oncology 20030301

• Neuron-specific enolase, nucleotides, nucleosides, purine bases, oxypurines and uric acid concentrations in cerebrospinal fluid of children with meningitis.

  Brain & development 20030301

• Inhibition of cyclic guanosine 5'-monophosphate-dependent protein kinase I (PKG-I) in lumbar spinal cord reduces formalin-induced hyperalgesia and PKG upregulation.

  Nitric oxide : biology and chemistry 20030301

• Purine and deazapurine nucleosides: synthetic approaches, molecular modelling and biological activity.

  Farmaco (Societa chimica italiana : 1989) 20030301

• Adenosine A1 receptor-mediated presynaptic inhibition of GABAergic transmission in immature rat hippocampal CA1 neurons.

  Journal of neurophysiology 20030301

• Regulation of lymphocyte-mediated killing by GTP-binding proteins.

  Journal of leukocyte biology 20030301

• Functional coupling of the human dopamine D2 receptor with G alpha i1, G alpha i2, G alpha i3 and G alpha o G proteins: evidence for agonist regulation of G protein selectivity.

  British journal of pharmacology 20030301

• The effect of lead ions on the energy metabolism of human erythrocytes in vitro.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20030301

• Complexes of cadmium ion with guanine bases detected by electrospray ionization mass spectrometry.

  Journal of mass spectrometry : JMS 20030301

• Effects of rolipram, pimobendan and zaprinast on ischaemia-induced dysrhythmias and on ventricular cyclic nucleotide content in the anaesthetized rat.

  European journal of anaesthesiology 20030301

• Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP.

  British journal of pharmacology 20030301

• h5-HT(1B) receptor-mediated constitutive Galphai3-protein activation in stably transfected Chinese hamster ovary cells: an antibody capture assay reveals protean efficacy of 5-HT.

  British journal of pharmacology 20030301

• Analysis of molecular determinants of affinity and relative efficacy of a series of R- and S-2-(dipropylamino)tetralins at the 5-HT1A serotonin receptor.

  British journal of pharmacology 20030301

• beta-MSH: a functional ligand that regulated energy homeostasis via hypothalamic MC4-R?

  Peptides 20030301

• Structural properties of the neutral and monoanionic forms of xanthosine, highly relevant to their substrate properties with various enzyme systems.

  Nucleosides, nucleotides & nucleic acids 20030301

• [Quantitation & optimization of guanosine fermentation process: prevention of NH4+ accumulation increases guanosine production by 70%].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20030301

• A spatial focusing model for G protein signals. Regulator of G protein signaling (RGS) protien-mediated kinetic scaffolding.

  The Journal of biological chemistry 20030227

• Effects of endogenous DNA base lesions on transcription elongation by mammalian RNA polymerase II. Implications for transcription-coupled DNA repair and transcriptional mutagenesis.

  The Journal of biological chemistry 20030227

• Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta.

  The Journal of biological chemistry 20030227

• A comparison between the distinct inward currents activated in rat cultured dorsal root ganglion neurones by intracellular flash photolysis of two forms of caged cyclic guanosine monophosphate.

  Neuroscience letters 20030227

• Syntheses and opioid receptor binding affinities of 8-amino-2,6-methano-3-benzazocines.

  Journal of medicinal chemistry 20030227

• Tandem electrostatic effect from the first to the third aglycon in the trimeric RNA owing to the nearest-neighbor interaction.

  Journal of the American Chemical Society 20030226

• Factors that contribute to efficient catalytic activity of a small Ca2+-dependent deoxyribozyme in relation to its RNA cleavage function.

  Biochemistry 20030225

• Identification of a novel protein with guanylyl cyclase activity in Arabidopsis thaliana.

  The Journal of biological chemistry 20030221

• Searching for allosteric effects via QSAR. Part II.

  Bioorganic & medicinal chemistry 20030220

• Basal activity of GIRK5 isoforms.

  Life sciences 20030214

• Critical role of N-terminal N-glycosylation for proper folding of the human formyl peptide receptor.

  Biochemical and biophysical research communications 20030214

• Synthesis, opioid receptor binding, and functional activity of 5'-substituted 17-cyclopropylmethylpyrido[2',3':6,7]morphinans.

  Bioorganic & medicinal chemistry letters 20030210

• AF2 interaction with Ascaris suum body wall muscle membranes involves G-protein activation.

  Biochemical and biophysical research communications 20030207

• Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide.

  Science (New York, N.Y.) 20030207

• Differential receptors create patterns diagnostic for ATP and GTP.

  Journal of the American Chemical Society 20030205

• The coenzyme thiamine pyrophosphate inhibits the self-splicing of the group I intron.

  The international journal of biochemistry & cell biology 20030201

• ATP-dependent interactions between Escherichia coli Min proteins and the phospholipid membrane in vitro.

  Journal of bacteriology 20030201

• The study of CXCR3 and CCR7 pharmacology using [35S]GTPgammaS exchange assays in cell membranes and permeabilized peripheral blood lymphocytes.

  Journal of immunological methods 20030201

• (2S,3R) beta-methyl-2',6'-dimethyltyrosine-L-tetrahydroisoquinoline-3-carboxylic acid [(2S,3R)TMT-L-Tic-OH] is a potent, selective delta-opioid receptor antagonist in mouse brain.

  The Journal of pharmacology and experimental therapeutics 20030201

• BAY41-2272, a novel nitric oxide independent soluble guanylate cyclase activator, relaxes human and rabbit corpus cavernosum in vitro.

  The Journal of urology 20030201

• Decreased modulation by lipopolysaccharide of aortic smooth muscle contractility in streptozotocin-induced hyperglycemic rats.

  Journal of cardiovascular pharmacology 20030201

• 8'-aminoguanosine inclusion results in enhanced efflux of taurine in preconditioned ischemic myocardium.

  Journal of cardiovascular pharmacology 20030201

• In vitro distribution and characterization of membrane-associated PLD and PI-PLC in Brassica napus.

  Journal of experimental botany 20030201

• Synergism of nitric oxide and maturation signals on human dendritic cells occurs through a cyclic GMP-dependent pathway.

  Journal of leukocyte biology 20030201

• Principles: extending the utility of [35S]GTP gamma S binding assays.

  Trends in pharmacological sciences 20030201

• Simultaneous determination of purine nucleotides, their metabolites and beta-nicotinamide adenine dinucleotide in cerebellar granule cells by ion-pair high performance liquid chromatography.

  Brain research. Brain research protocols 20030201

• Dependence of the coupling of dopamine receptors to G proteins on the protein redox state in the neural plasma membranes of pond snail.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030201

• A unique phenotype of 5-HT2C, agonist-induced GTPgamma35S binding, transferable to 5-HT2A and 5-HT2B, upon swapping intracellular regions.

  British journal of pharmacology 20030201

• Nod factors activate both heterotrimeric and monomeric G-proteins in Vigna unguiculata (L.) Walp.

  Planta 20030201

• Molecular evidence for the functional role of dopamine D3 receptor in the morphine-induced rewarding effect and hyperlocomotion.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030201

• G protein signaling in a neuronal network is necessary for rhythmic motor pattern production.

  Journal of neurophysiology 20030201

• Mycophenolic acid-induced apoptotic signal transduction in MOLT-4 T-cell.

  Transplantation proceedings 20030201

• UFP-101, a high affinity antagonist for the nociceptin/orphanin FQ receptor: radioligand and GTPgamma(35)S binding studies.

  Naunyn-Schmiedeberg's archives of pharmacology 20030201

• Antagonism of adenosine receptors by caffeine and caffeine metabolites in equine forebrain tissues.

  American journal of veterinary research 20030201

• Paracrine role of soluble guanylate cyclase and type III nitric oxide synthase in ovine fetal pulmonary circulation: a double labeling immunohistochemical study.

  Histochemistry and cell biology 20030201

• Inhibiting Ras signaling in the therapy of breast cancer.

  Clinical breast cancer 20030201

• Alkaline hydrolysis of cladribine.

  Die Pharmazie 20030201

• Biosynthesis of the 7-deazaguanosine hypermodified nucleosides of transfer RNA.

  Bioorganic chemistry 20030201

• Synthesis and biological activities of 2-functionalized purine nucleosides.

  Nucleosides, nucleotides & nucleic acids 20030201

• Guanine nucleotides guanosine 5'-diphosphate 3'-diphosphate and GTP co-operatively regulate the production of an antibiotic bacilysin in Bacillus subtilis.

  The Journal of biological chemistry 20030124

• ADP-ribosylation factor 4 small GTPase mediates epidermal growth factor receptor-dependent phospholipase D2 activation.

  The Journal of biological chemistry 20030124

• Interaction of human telomerase with its primer substrate.

  Biochemistry 20030121

• A ribozyme with michaelase activity: synthesis of the substrate precursors.

  Bioorganic & medicinal chemistry 20030117

• Effects of stress and tranylcypromine on amphetamine-induced locomotor activity and GABA(B) receptor function in rat brain.

  Life sciences 20030117

• Long-term interactions between opioid and cannabinoid agonists at the cellular level: cross-desensitization and downregulation.

  Brain research 20030117

• Alteration of 8-hydroxyguanosine concentrations in the cerebrospinal fluid and serum from patients with Parkinson's disease.

  Neuroscience letters 20030116

• Novel hexahydrospiro[piperidine-4,1'-pyrrolo[3,4-c]pyrroles]: highly selective small-molecule nociceptin/orphanin FQ receptor agonists.

  Journal of medicinal chemistry 20030116

• Endogenous phospholipase D2 localizes to the plasma membrane of RBL-2H3 mast cells and can be distinguished from ADP ribosylation factor-stimulated phospholipase D1 activity by its specific sensitivity to oleic acid.

  The Biochemical journal 20030115

• Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance.

  Biochemical pharmacology 20030115

• Antiemetic and motor-depressive actions of CP55,940: cannabinoid CB1 receptor characterization, distribution, and G-protein activation.

  European journal of pharmacology 20030110

• Highly selective binding of organometallic ruthenium ethylenediamine complexes to nucleic acids: novel recognition mechanisms.

  Journal of the American Chemical Society 20030108

• Signal transduction of somatostatin in human B lymphoblasts.

  American journal of physiology. Cell physiology 20030101

• Cholesterol cell content modulates GTPase activity of G proteins in GH4C1 cell membranes.

  Cellular signalling 20030101

• P2Y(1) receptor activation inhibits NMDA receptor-channels in layer V pyramidal neurons of the rat prefrontal and parietal cortex.

  Neurochemistry international 20030101

• Ribavirin inhibits DNA, RNA, and protein synthesis in PHA-stimulated human peripheral blood mononuclear cells: possible explanation for therapeutic efficacy in patients with chronic HCV infection.

  Journal of medical virology 20030101

• The salivary purine nucleosidase of the mosquito, Aedes aegypti.

  Insect biochemistry and molecular biology 20030101

• Opioid receptor-induced GTPgamma35S binding during mouse development.

  Developmental biology 20030101

• Quinine inhibits vascular contraction independent of effects on calcium or myosin phosphorylation.

  The Journal of pharmacology and experimental therapeutics 20030101

• Constitutive coupling of a chimeric dopamine D2/alpha 1B receptor to the phospholipase C pathway: inverse agonism to silent antagonism by neuroleptic drugs.

  The Journal of pharmacology and experimental therapeutics 20030101

• Crystallization and preliminary X-ray crystallographic analysis of tRNA(m1G37)methyltransferase from Haemophilus influenzae.

  Acta crystallographica. Section D, Biological crystallography 20030101

• P53 mediates the apoptotic response to GTP depletion after renal ischemia-reperfusion: protective role of a p53 inhibitor.

  Journal of the American Society of Nephrology : JASN 20030101

• Metabotropic glutamate receptors promote neuronal and vascular plasticity through novel intracellular pathways.

  Histology and histopathology 20030101

• Determination of total potentially available nucleosides in human milk from Asian women.

  Nutrition (Burbank, Los Angeles County, Calif.) 20030101

• Activity of opioid ligands in cells expressing cloned mu opioid receptors.

  BMC pharmacology 20030101

• Acetylcholine-induced vasodilation may depend entirely upon NO in the femoral artery of young piglets.

  British journal of pharmacology 20030101

• Clustering of nucleosides in the presence of alkali metals: Biologically relevant quartets of guanosine, deoxyguanosine and uridine observed by ESI-MS/MS.

  Journal of mass spectrometry : JMS 20030101

• Nitric oxide decreases the production of inositol phosphates stimulated by angiotensin II and thyrotropin-releasing hormone in anterior pituitary cells.

  European journal of endocrinology 20030101

• A novel assay system implicates PtdIns(3,4)P(2), PtdIns(3)P, and PKC delta in intracellular production of reactive oxygen species by the NADPH oxidase.

  Molecular cell 20030101

• Suppression of the morphine-induced rewarding effect and G-protein activation in the lower midbrain following nerve injury in the mouse: involvement of G-protein-coupled receptor kinase 2.

  Neuroscience 20030101

• Mycophenolic acid inhibits inosine 5'-monophosphate dehydrogenase and suppresses immunoglobulin and cytokine production of B cells.

  International immunopharmacology 20030101

• Functional interaction of CFTR and ENaC in sweat glands.

  Pflugers Archiv : European journal of physiology 20030101

• Chronic fluoxetine induces opposite changes in G protein coupling at pre and postsynaptic 5-HT1A receptors in rat brain.

  Neuropharmacology 20030101

• Maturation alters cyclic nucleotide and relaxation responses to nitric oxide donors in ovine cerebral arteries.

  Biology of the neonate 20030101

• The bradykinin BK2 receptor mediates angiotensin II receptor type 2 stimulated rat duodenal mucosal alkaline secretion.

  BMC physiology 20030101

• Functional characterisation of the putative somatostatin sst2 receptor antagonist CYN 154806.

  Naunyn-Schmiedeberg's archives of pharmacology 20030101

• Role of the M2 muscarinic receptor pathway in lidocaine-induced potentiation of the relaxant response to atrial natriuretic peptide in bovine tracheal smooth muscle.

  Naunyn-Schmiedeberg's archives of pharmacology 20030101

• Roles of cyclic GMP in modulating ovarian functions.

  Reproductive biomedicine online 20030101

• Relationship between the nonlinear ferroelectric and liquid crystal models for microtubules.

  Physical review. E, Statistical, nonlinear, and soft matter physics 20030101

• Mu opioid receptor signaling in morphine sensitization.

  Neuroscience 20030101

• The angiotensin II receptor type 2 agonist CGP 42112A stimulates NO production in the porcine jejunal mucosa.

  BMC pharmacology 20030101

• Signaling through NO and cGMP-dependent protein kinases.

  Annals of medicine 20030101

• Evidence for disaggregation of oligomeric G(o)alpha induced by guanosine-5;-3-O-(thio)triphosphate activation.

  Biochemistry. Biokhimiia 20030101

• Structure-activity relationships of dynorphin analogs substituted in positions 2 and 3.

  Biopolymers 20030101

• Genetic instability of (GATA)n microsatellite DNA repeats and somatic mosaicism in the unisexual lizards Darevskia unisexualis.

  Doklady. Biochemistry and biophysics 20030101

• Covalent binding of leukotriene A4 to nucleosides, nucleotides, and nucleic acids.

  Advances in experimental medicine and biology 20030101

• Chemical modifications of alpha1,6-fucosyltransferase define amino acid residues of catalytic importance.

  Biochimie 20030101

• Inflammatory breast cancer: relationship between growth factor signaling and motility in aggressive cancers.

  Breast cancer research : BCR 20030101

• Activation of A(3) receptors by endogenous adenosine inhibits synaptic transmission during hypoxia in rat cortical neurons.

  Restorative neurology and neuroscience 20030101

• Wegener's granulomatosis: current and upcoming therapies.

  Arthritis research & therapy 20030101

• Evidence of increased dopamine receptor signaling in food-restricted rats.

  Neuroscience 20030101

• Drosophila S3 ribosomal protein accelerates repair of 8-oxoguanine performed by human and mouse cell extracts.

  Environmental and molecular mutagenesis 20030101

• Nitric oxide synthase activity in human trophoblast, term placenta and pregnant myometrium.

  Reproductive biology and endocrinology : RB&E 20030101

• Changes in hippocampal histamine receptors across the hibernation cycle in ground squirrels.

  Hippocampus 20030101

• Valacyclovir in the treatment of herpes simplex, herpes zoster, and other viral infections.

  Journal of cutaneous medicine and surgery 20030101

• Increased brain histamine H3 receptor expression during hibernation in golden-mantled ground squirrels.

  BMC neuroscience 20030101

• Design, synthesis and analysis of antiviral nucleosides bearing pyrrolepolyamide binding to nucleic acid (II): N2-pyrrolepolyamidopropylguanosine.

  Nucleic acids research. Supplement (2001) 20030101

• Conformationally constrained tricyclic nucleosides. Role of electronic and steric factors.

  Nucleic acids research. Supplement (2001) 20030101

• Properties of Arg389-beta1-adrenoceptor-Gsalpha fusion proteins: comparison with Gly389-beta1-adrenoceptor-Gsalpha fusion proteins.

  Receptors & channels 20030101

• G-protein modulators alter the swimming behavior and calcium influx of Paramecium tetraurelia.

  The Journal of eukaryotic microbiology 20030101

• MDPSCL2: a new protecting group for chemoselective synthesis of 2'-O-alkylated guanosines.

  Nucleosides, nucleotides & nucleic acids 20030101

• Synthesis of novel mRNA 5' cap-analogues: dinucleoside P1, P3-tri-, P1, P4-tetra-, and P1, P5-pentaphosphates.

  Nucleosides, nucleotides & nucleic acids 20030101

• Rearrangement reactions of guanosine cyclonucleosides and their analogs.

  Nucleosides, nucleotides & nucleic acids 20030101

• Dinucleoside monophosphates containing AZT and 1-methyladenosine or 7-methylguanosine.

  Nucleosides, nucleotides & nucleic acids 20030101

• Synthesis and conformational properties of O-beta-D-ribofuranosyl-(1''-2')-guanosine and (adenosine)-5''-phosphate.

  Nucleosides, nucleotides & nucleic acids 20030101

• Oligonucleotides incorporating 7-(aminoalkyn-1-yl)-7-deaza-2'-deoxyguanosines: duplex stability and phosphodiester hydrolysis by exonucleases.

  Nucleosides, nucleotides & nucleic acids 20030101

• Oligonucleotides incorporating N7-(2'-deoxy-beta-D-erythro-pentofuranosyl)isoguanine.

  Nucleosides, nucleotides & nucleic acids 20030101

• Preparation of 6-thioguanosine phosphoramidite for oligoribonucleotide synthesis.

  Nucleosides, nucleotides & nucleic acids 20030101

• Process development for the synthesis of 5'-O-(4,4'-dimethoxytrityl)-N2-isobutyryl-2'-O-(2-methoxyethyl)-guanosine--a potential precursor for the second generation antisense oligonucleotides: an improved process for the preparation of 2'-O-alkyl-2,6-diaminopurine riboside.

  Nucleosides, nucleotides & nucleic acids 20030101

• Oxidation of guanine nucleosides to 4-amidinocarbamoyl-5-hydroxyimidazoles by dimethyldioxirane.

  Nucleosides, nucleotides & nucleic acids 20030101

• 5'-O-fluorosulfonylbenzoyl esters of purine nucleosides as potential inhibitors of NTPase/helicase and polymerase of Flaviviridae viruses.

  Nucleosides, nucleotides & nucleic acids 20030101

• Thermodynamics of 7-methylguanosine cation stacking with tryptophan upon mRNA 5' cap binding to translation factor eIF4E.

  Nucleosides, nucleotides & nucleic acids 20030101

• Conformationally restricted 2-substituted wyosine derivatives. 1H, 13C, and 15N NMR study.

  Nucleosides, nucleotides & nucleic acids 20030101

• Expression of alternatively spliced isoforms of human Sp7 in osteoblast-like cells.

  BMC genomics 20030101

• Hydrolytic cleavage of purine ribonucleosides in Aspergillus phoenicis.

  Journal of basic microbiology 20030101

• Synthesis of L-ascorbic acid in the phloem.

  BMC plant biology 20030101

• Evidence for the extrapulmonary localization of inhaled nitric oxide.

  Heart disease (Hagerstown, Md.) 20030101

• Enhanced spontaneous activity of the mu opioid receptor by cysteine mutations: characterization of a tool for inverse agonist screening.

  BMC pharmacology 20030101

• Normoblastosis, a murine model for ankyrin-deficient hemolytic anemia, is caused by a hypomorphic mutation in the erythroid ankyrin gene Ank1.

  The hematology journal : the official journal of the European Haematology Association 20030101

• The tyranny of adenosine recognition among RNA aptamers to coenzyme A.

  BMC evolutionary biology 20030101

• Guanosine deaminase in human serum and tissue extracts--a reappraisal of the products.

  British journal of biomedical science 20030101

• Effect of cGMP on lung microvascular endothelial barrier dysfunction following hydrogen peroxide.

  Endothelium : journal of endothelial cell research 20030101

• Isolation and characterization of 190K protein from aorta smooth muscle.

  Advances in experimental medicine and biology 20030101

• Impact of genetic polymorphisms on the smoking-related risk of periodontal disease: the population-based study SHIP.

  Tobacco induced diseases 20030101

• Cannabinoid pharmacology: implications for additional cannabinoid receptor subtypes.

  Chemistry and physics of lipids 20021231

• Effects of mutations in the highly conserved DRY motif on binding affinity, expression, and G-protein recruitment of the human angiotensin II type-2 receptor.

  Brain research. Molecular brain research 20021230

• Regulation of phospholipase D activity by actin. Actin exerts bidirectional modulation of Mammalian phospholipase D activity in a polymerization-dependent, isoform-specific manner.

  The Journal of biological chemistry 20021227

• Pertussis toxin-insensitive activation of the heterotrimeric G-proteins Gi/Go by the NG108-15 G-protein activator.

  The Journal of biological chemistry 20021227

• Loss of mu-opioid receptor-mediated G-protein activation in the pons/medulla of mice lacking the exons 2 and 3 of mu-opioid receptor gene.

  Neuroscience letters 20021225

• In vitro nucleotide misinsertion opposite the oxidized guanosine lesions spiroiminodihydantoin and guanidinohydantoin and DNA synthesis past the lesions using Escherichia coli DNA polymerase I (Klenow fragment).

  Biochemistry 20021224

• A severe variant of childhood ataxia with central hypomyelination/vanishing white matter leukoencephalopathy related to EIF21B5 mutation.

  Neurology 20021224

• X-ray structure of two crystalline forms of a streptomycete ribonuclease with cytotoxic activity.

  The Journal of biological chemistry 20021206

• Arf1 dissociates from the clathrin adaptor GGA prior to being inactivated by Arf GTPase-activating proteins.

  The Journal of biological chemistry 20021206

• Selective heterologous regulation of 5-HT1A receptor-stimulated 35S GTPgammaS binding in the anterior cingulate cortex as a result of 5-HT2 receptor activation.

  Brain research 20021206

• Structural effects of cytosine methylation on DNA sugar pucker studied by FTIR.

  Journal of molecular biology 20021206

• Signaling of rat Frizzled-2 through phosphodiesterase and cyclic GMP.

  Science (New York, N.Y.) 20021206

• Identification of full, partial and inverse CC chemokine receptor 3 agonists using [35S]GTPgammaS binding.

  European journal of pharmacology 20021205

• PF4, a FMRFamide-related peptide, gates low-conductance Cl(-) channels in Ascaris suum.

  European journal of pharmacology 20021205

• Energetics of hydrogen bond networks in RNA: hydrogen bonds surrounding G+1 and U42 are the major determinants for the tertiary structure stability of the hairpin ribozyme.

  Biochemistry 20021203

• Sphingosylphosphorylcholine-induced contraction of feline ileal smooth muscle cells is mediated by Galphai3 protein and MAPK.

  Cellular signalling 20021201

• SR-141716A-induced stimulation of locomotor activity. A structure-activity relationship study.

  Pharmacology, biochemistry, and behavior 20021201

• Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20021201

• Novel beta2-adrenergic receptor signaling pathways.

  The Journal of allergy and clinical immunology 20021201

• Role of G protein and protein kinase signalling in influenza virus budding in MDCK cells.

  The Journal of general virology 20021201

• Different roles for Gi and Go proteins in modulation of adenylyl cyclase type-2 activity.

  Journal of neurochemistry 20021201

• Effect of ischemic preconditioning on hepatic microcirculation and function in a rat model of ischemia reperfusion injury.

  Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20021201

• Ultraviolet-B-induced inactivation of human OGG1, the repair enzyme for removal of 8-oxoguanine in DNA.

  Photochemistry and photobiology 20021201

• Rapid uncoupling of serotonin-1A receptors in rat hippocampus by 17beta-estradiol in vitro requires protein kinases A and C.

  Neuroendocrinology 20021201

• Genistein and tyrphostin AG 556 block the action potential shortening in septic shock.

  Zhonghua yi xue za zhi = Chinese medical journal; Free China ed 20021201

• Rho-kinase inhibitors: pharmacomodulations on the lead compound Y-32885.

  Journal of enzyme inhibition and medicinal chemistry 20021201

• Probing opioid receptor interactions with azacycloalkane amino acids. Synthesis of a potent and selective ORL1 antagonist.

  Journal of medicinal chemistry 20021121

• Synthesis and biological evaluation of 14-alkoxymorphinans. 17. Highly delta opioid receptor selective 14-alkoxy-substituted indolo- and benzofuromorphinans.

  Journal of medicinal chemistry 20021121

• Efficient adenylyl cyclase activation by a beta2-adrenoceptor-G(i)alpha2 fusion protein.

  Biochemical and biophysical research communications 20021115

• Characterization of the interactions between the small GTPase RhoA and its guanine nucleotide exchange factors.

  Analytical biochemistry 20021115

• Two distinct signaling pathways upregulate NMDA receptor responses via two distinct metabotropic glutamate receptor subtypes.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20021115

• Guanosine nucleotides inhibit different syndromes of PTHrP excess caused by human cancers in vivo.

  The Journal of clinical investigation 20021115

• Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies.

  Neuroreport 20021115

• Synthesis and structure-activity relationships of aminoalkylazetidines as ORL1 receptor ligands.

  Bioorganic & medicinal chemistry letters 20021104

• Modulation of cGMP by human HO-1 retrovirus gene transfer in pulmonary microvessel endothelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20021101

• G protein modulates thyroid hormone-induced Na(+) channel activation in ventricular myocytes.

  American journal of physiology. Heart and circulatory physiology 20021101

• Modulation of group II metabotropic glutamate receptor signaling by chronic cocaine.

  The Journal of pharmacology and experimental therapeutics 20021101

• Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. II. Agonist and antagonist properties at subtypes of dopamine D(2)-like receptor and alpha(1)/alpha(2)-adrenoceptor.

  The Journal of pharmacology and experimental therapeutics 20021101

• Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. III. Agonist and antagonist properties at serotonin, 5-HT(1) and 5-HT(2), receptor subtypes.

  The Journal of pharmacology and experimental therapeutics 20021101

• Reduction of arsenate to arsenite in hepatic cytosol.

  Toxicological sciences : an official journal of the Society of Toxicology 20021101

• Purine nucleoside phosphorylase as a cytosolic arsenate reductase.

  Toxicological sciences : an official journal of the Society of Toxicology 20021101

• Remarkable increase in the concentration of 8-hydroxyguanosine in cerebrospinal fluid from patients with Alzheimer's disease.

  Journal of neuroscience research 20021101

• Functions of IkappaB proteins in inflammatory responses to Escherichia coli LPS in mouse lungs.

  American journal of respiratory cell and molecular biology 20021101

• Synthesis of 2'-O-methoxyethylguanosine using a novel silicon-based protecting group.

  The Journal of organic chemistry 20021101

• DNA-phospholipid recognition: modulation by metal ion and lipid nature. Complexes structure and stability calculated by molecular mechanics.

  Bioelectrochemistry (Amsterdam, Netherlands) 20021101

• Autosomal-dominant hypoplastic form of amelogenesis imperfecta caused by an enamelin gene mutation at the exon-intron boundary.

  Journal of dental research 20021101

• Cyclic nucleotide content of tobacco BY-2 cells.

  Phytochemistry 20021101

• The protective effects of taurine against renal damage by salt loading in Dahl salt-sensitive rats.

  Journal of hypertension 20021101

• Large-amplitude 5-HT1A receptor activation: a new mechanism of profound, central analgesia.

  Neuropharmacology 20021101

• Angiotensin AT(1)-receptors depolarize neonatal spinal motoneurons and other ventral horn neurons via two different conductances.

  Journal of neurophysiology 20021101

• Group I introns and RNA folding.

  Biochemical Society transactions 20021101

• Insulin influences the nitric oxide cyclic nucleotide pathway in cultured human smooth muscle cells from corpus cavernosum by rapidly activating a constitutive nitric oxide synthase.

  European journal of endocrinology 20021101

• Possible signaling by glutathione and its novel analogue through potent stimulation of fontocortical G proteins in normal aging and in Alzheimer's disease.

  Annals of the New York Academy of Sciences 20021101

• Streptozotocin-induced diabetes impairs G-protein linked signal transduction in vascular smooth muscle.

  Molecular and cellular biochemistry 20021101

• Implication of guanosine 3',5'-cyclic monophosphate, adenosine 3',5'-cyclic monophosphate, adenosine 5'-mono-, di- and triphosphate and fructose-2,6-bisphosphate in the regulation of the glycolytic pathway in hypoxic/anoxic mussel, Mytilus galloprovincialis.

  Molecular and cellular biochemistry 20021101

• [The roles of DNA methylation in human neoplasms].

  Ai zheng = Aizheng = Chinese journal of cancer 20021101

• Syntheses of specifically 15N-labeled adenosine and guanosine.

  Current protocols in nucleic acid chemistry 20021101

• Sequence requirements in the catalytic core of the '10-23' DNA enzyme.

  The Journal of biological chemistry 20021025

• Fluorescence analysis of receptor-G protein interactions in cell membranes.

  Biochemistry 20021022

• The mechanism of docosahexaenoic acid-induced phospholipase D activation in human lymphocytes involves exclusion of the enzyme from lipid rafts.

  The Journal of biological chemistry 20021018

• A partial copy of msDNA from a new retron element is likely a retrotransposed DNA found in the myxobacterium Nannocystis exedens.

  Gene 20021016

• Thermodynamic contributions for the incorporation of GTA triplets within canonical TAT/TAT and C+GC/C+GC base-triplet stacks of DNA triplexes.

  Biochemistry 20021015

• DNA-induced polymerization of HIV-1 integrase analyzed with fluorescence fluctuation spectroscopy.

  The Journal of biological chemistry 20021011

• G protein-independent activation of an inward Na(+) current by muscarinic receptors in mouse pancreatic beta-cells.

  The Journal of biological chemistry 20021011

• Pb EXAFS studies on DNA quadruplexes: identification of metal ion binding site.

  Biochemistry 20021008

• Influence of a deletion of protein kinase C gamma isoform in the G-protein activation mediated through opioid receptor-like-1 and mu-opioid receptors in the mouse pons/medulla.

  Neuroscience letters 20021004

• The effect of sildenafil on human vascular function, platelet activation, and myocardial ischemia.

  Journal of the American College of Cardiology 20021002

• Ligand modulation of [35S]GTPgammaS binding at human alpha(2A), alpha(2B) and alpha(2C) adrenoceptors.

  Cellular signalling 20021001

• Effect of chronic administration of R-(+)-[2,3-Dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazinyl]-(1-naphthalenyl)methanone mesylate (WIN55,212-2) or delta(9)-tetrahydrocannabinol on cannabinoid receptor adaptation in mice.

  The Journal of pharmacology and experimental therapeutics 20021001

• Tranilast inhibits cytokine-induced nuclear factor kappaB activation in vascular endothelial cells.

  Molecular pharmacology 20021001

• Stimulation of muscarinic M2 receptors inhibits atrial natriuretic peptide-mediated relaxation in bovine tracheal smooth muscle.

  Naunyn-Schmiedeberg's archives of pharmacology 20021001

• Communications between the high-affinity cyclic nucleotide binding sites in E. coli cyclic AMP receptor protein: effect of single site mutations.

  Biochemistry 20021001

• Mature form of adrenomedullin is a useful marker to evaluate blood volume in hemodialysis patients.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20021001

• Isolation and enzymatic characterization of lamjapin, the first ribosome-inactivating protein from cryptogamic algal plant (Laminaria japonica A).

  European journal of biochemistry 20021001

• Sodium glucose-linked transport in the ruminal epithelium of fallow deer -- comparison to sheep.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20021001

• The structure of the RlmB 23S rRNA methyltransferase reveals a new methyltransferase fold with a unique knot.

  Structure (London, England : 1993) 20021001

• Inhibition of O6-alkylguanine-DNA alkyltransferase by O6-benzyl-N2-acetylguanosine increases chloroethylnitrosourea-induced apoptosis in Mer+ human melanoma cells.

  Melanoma research 20021001

• A rifampicin resistance mutation in the rpoB gene confers ppGpp-independent antibiotic production in Streptomyces coelicolor A3(2).

  Molecular genetics and genomics : MGG 20021001

• Lignans isolated from valerian: identification and characterization of a new olivil derivative with partial agonistic activity at A(1) adenosine receptors.

  Journal of natural products 20021001

• Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA.

  RNA (New York, N.Y.) 20021001

• Estrogen modulation of mu-opioid receptor-stimulated [35S]-GTP-gamma-S binding in female rat brain visualized by in vitro autoradiography.

  Neuroendocrinology 20021001

• Dissection of the mechanism for the stringent factor RelA.

  Molecular cell 20021001

• Structure and potential mutagenicity of new hydantoin products from guanosine and 8-oxo-7,8-dihydroguanine oxidation by transition metals.

  Environmental health perspectives 20021001

• Determination of monophosphate nucleotides by capillary electrophoresis inductively coupled plasma mass spectrometry.

  The Analyst 20021001

• Effects of cilostazol, a selective cyclic AMP phosphodiesterase inhibitor on isolated rabbit spinal arterioles.

  The Japanese journal of physiology 20021001

• Neurodegenerative mechanisms in subacute sclerosing panencephalitis.

  Journal of child neurology 20021001

• Cellular localization of cannabinoid receptors and activated G-proteins in rat anterior cingulate cortex.

  Life sciences 20020927

• Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary.

  Journal of medicinal chemistry 20020926

• The active site of arsenite oxidase from Alcaligenes faecalis.

  Journal of the American Chemical Society 20020925

• Adenosine production and its interaction with protection of ischemic and reperfusion injury of the myocardium.

  Life sciences 20020920

• Thrombin receptors activate G(o) proteins in endothelial cells to regulate intracellular calcium and cell shape changes.

  The Journal of biological chemistry 20020913

• Hypersensitivity of dopamine transmission in the rat striatum after treatment with the NMDA receptor antagonist amantadine.

  Brain research 20020913

• L-methionine inhibits reaction of DNA with anticancer cis-diamminedichloroplatinum(II).

  Biochemistry 20020910

• Interactions of valerian extracts and a fixed valerian-hop extract combination with adenosine receptors.

  Life sciences 20020906

• Specific, sensitive and accurate LC-MS/MS method for the measurement of levovirin in rat and monkey plasma.

  Journal of pharmaceutical and biomedical analysis 20020905

• Spermine increases phosphatidylinositol 4,5-bisphosphate content in permeabilized and nonpermeabilized HL60 cells.

  Biochimica et biophysica acta 20020905

• Alterations of sarcolemmal phospholipase D and phosphatidate phosphohydrolase in congestive heart failure.

  Biochimica et biophysica acta 20020905

• 13C and (15)N chemical shift tensors in adenosine, guanosine dihydrate, 2'-deoxythymidine, and cytidine.

  Journal of the American Chemical Society 20020904

• Receptor (MT(1)) mediated influence of melatonin on cAMP concentration and insulin secretion of rat insulinoma cells INS-1.

  Journal of pineal research 20020901

• CNP production in the kidney and effects of protein intake restriction in nephrotic syndrome.

  American journal of physiology. Renal physiology 20020901

• Relaxation and potentiation of cGMP-mediated response by ibudilast in bovine tracheal smooth muscle.

  Naunyn-Schmiedeberg's archives of pharmacology 20020901

• Inhibitory effects of a dominant-interfering form of the Rho-GTPase Cdc42 in the chemoattractant-elicited signaling pathways leading to NADPH oxidase activation in differentiated HL-60 cells.

  Blood 20020901

• Measures of efficacy using G proteins as endpoints: differential engagement of G proteins through single receptors.

  Molecular pharmacology 20020901

• Depletion of intracellular GTP results in nuclear factor-kappaB activation and intercellular adhesion molecule-1 expression in human endothelial cells.

  Molecular pharmacology 20020901

• Differential activation of Gq/11 and Gi(3) proteins at 5-hydroxytryptamine(2C) receptors revealed by antibody capture assays: influence of receptor reserve and relationship to agonist-directed trafficking.

  Molecular pharmacology 20020901

• Generation and analysis of constitutively active and physically destabilized mutants of the human beta(1)-adrenoceptor.

  Molecular pharmacology 20020901

• Potentiation of slow component of delayed rectifier K(+) current by cGMP via two distinct mechanisms: inhibition of phosphodiesterase 3 and activation of protein kinase G.

  British journal of pharmacology 20020901

• Chronic agonist treatment converts antagonists into inverse agonists at delta-opioid receptors.

  The Journal of pharmacology and experimental therapeutics 20020901

• Measurement of agonist-dependent and -independent signal initiation of alpha(1b)-adrenoceptor mutants by direct analysis of guanine nucleotide exchange on the G protein galpha(11).

  The Journal of pharmacology and experimental therapeutics 20020901

• Increased dopamine receptor signaling and dopamine receptor-G protein coupling in denervated striatum.

  The Journal of pharmacology and experimental therapeutics 20020901

• Behavioral and neurochemical effects of 5-(4-[4-(5-Cyano-3-indolyl)-butyl)-butyl]-1-piperazinyl)-benzofuran-2-carboxamide (EMD 68843): a combined selective inhibitor of serotonin reuptake and 5-hydroxytryptamine(1A) receptor partial agonist.

  The Journal of pharmacology and experimental therapeutics 20020901

• Characterization of pharmacological efficacy of VX-148, a new, potent immunosuppressive inosine 5'-monophosphate dehydrogenase inhibitor.

  The Journal of pharmacology and experimental therapeutics 20020901

• Mycophenolic acid inhibits IL-2-dependent T cell proliferation, but not IL-2-dependent survival and sensitization to apoptosis.

  Journal of immunology (Baltimore, Md. : 1950) 20020901

• cGMP/protein kinase G-dependent inhibition of N-type Ca2+ channels induced by nitric oxide in human neuroblastoma IMR32 cells.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20020901

• Melatonin potentiates phenylephrine-stimulated intracellular Ca2+ transient in smooth muscle cell of large arteries of chick embryo.

  Journal of cardiovascular pharmacology 20020901

• Inhibitory activity of dioxolane purine analogs on wild-type and lamivudine-resistant mutants of hepadnaviruses.

  Hepatology (Baltimore, Md.) 20020901

• Mycophenolic acid downregulates inducible nitric oxide synthase induction in astrocytes.

  Glia 20020901

• Relaxation and cGMP formation in response to sildenafil and sodium nitroprusside in saphenous veins from normotensive and hypertensive patients.

  American journal of hypertension 20020901

• Chronic imidazoline receptor activation in spontaneously hypertensive rats.

  American journal of hypertension 20020901

• Human leptin stimulates systemic nitric oxide production in the rat.

  Obesity research 20020901

• GTP gamma S-stimulated lysosomal lysis dependent on the assembly of adaptor protein on lysosome.

  Biological & pharmaceutical bulletin 20020901

• Homocysteine enhances impairment of endothelium-dependent relaxation and guanosine cyclic monophosphate formation in aortae from diabetic rabbits.

  Diabetologia 20020901

• Influence of the relA gene on ribosome frameshifting.

  Molecular genetics and genomics : MGG 20020901

• Mechanisms of ligand binding and efficacy at the human D2(short) dopamine receptor.

  Journal of neurochemistry 20020901

• Suppression of the morphine-induced rewarding effect in the rat with neuropathic pain: implication of the reduction in mu-opioid receptor functions in the ventral tegmental area.

  Journal of neurochemistry 20020901

• Distribution of NO-induced cGMP-like immunoreactive neurones in the abdominal nervous system of the crayfish, Procambarus clarkii.

  Zoological science 20020901

• Nucleosides are efficiently absorbed by Na(+)-dependent transport across the intestinal brush border membrane in veal calves.

  Journal of dairy science 20020901

• Functional coupling of capping and transcription of mRNA.

  Molecular cell 20020901

• External GTP binding and induction of cell division in starved Tetrahymena thermophila.

  European journal of cell biology 20020901

• [Analysis on metabolic flux shift during guanosine fermentation].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20020901

• [Determination of nucleosides in siweilingzhi mixture by HPCE].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20020901

• Identification of a novel human eicosanoid receptor coupled to G(i/o).

  The Journal of biological chemistry 20020830

• RhoA-mediated Ca2+ sensitization in erectile function.

  The Journal of biological chemistry 20020823

• DNA oxidation by peroxo-chromium(v) species: oxidation of guanosine to guanidinohydantoin.

  Chemical communications (Cambridge, England) 20020821

• The purine nucleoside phosphorylase from Trichomonas vaginalis is a homologue of the bacterial enzyme.

  Biochemistry 20020820

• G protein-coupled receptor for nicotinic acid in mouse macrophages.

  Biochemical pharmacology 20020815

• Photosensitized oxidation of 13C,15N-labeled imidazole derivatives.

  Journal of the American Chemical Society 20020814

• Conformational changes in the amino-terminal helix of the G protein alpha(i1) following dissociation from Gbetagamma subunit and activation.

  Biochemistry 20020806

• Inactivation of mammalian 8-oxoguanine-DNA glycosylase by cadmium(II): implications for cadmium genotoxicity.

  DNA repair 20020806

• Base pairing properties of 8-oxo-7,8-dihydroadenosine in cDNA synthesis by reverse transcriptases.

  Bioorganic & medicinal chemistry letters 20020805

• Beta-arrestins regulate a Ral-GDS Ral effector pathway that mediates cytoskeletal reorganization.

  Nature cell biology 20020801

• Specificity of human and rat orthologs of the concentrative nucleoside transporter, SPNT.

  American journal of physiology. Renal physiology 20020801

• Inhibition of inwardly rectifying K(+) channels by cGMP in pulmonary vascular endothelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20020801

• Atomic resolution data reveal flexibility in the structure of RNase Sa.

  Acta crystallographica. Section D, Biological crystallography 20020801

• Comparison of radiolabeled nucleoside probes (FIAU, FHBG, and FHPG) for PET imaging of HSV1-tk gene expression.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20020801

• Down-regulation of multiple low dose streptozotocin-induced diabetes by mycophenolate mofetil.

  Clinical and experimental immunology 20020801

• On-line fourier transform infrared detection in capillary electrophoresis.

  Analytical chemistry 20020801

• Permeability of Coxiella burnetii to ribonucleosides.

  Microbiology (Reading, England) 20020801

• Xanthosine and xanthine. Substrate properties with purine nucleoside phosphorylases, and relevance to other enzyme systems.

  European journal of biochemistry 20020801

• Heterodimerization of gamma-aminobutyric acid B receptor subunits as revealed by the yeast two-hybrid system.

  Methods (San Diego, Calif.) 20020801

• Do mRNA and rRNA binding sites of E.coli ribosomal protein S15 share common structural determinants?

  Journal of molecular biology 20020726

• M1 muscarinic receptor signaling in mouse hippocampus and cortex.

  Brain research 20020719

• Brain regional mu-opioid receptor function in rat lines selected for differences in alcohol preference.

  European journal of pharmacology 20020719

• Effects of dinucleoside polyphosphates on regulation of coronary vascular tone.

  European journal of pharmacology 20020719

• Membrane-bound progesterone receptors coupled to G proteins in the fungus Rhizopus nigricans.

  FEMS microbiology letters 20020716

• Vps4-A (vacuolar protein sorting 4-A) is a binding partner for a novel Rho family GTPase, Rnd2.

  The Biochemical journal 20020715

• Comparison between the effects of the rapid recombinant insulin analog aspart and those of human regular insulin on platelet cyclic nucleotides and aggregation.

  Thrombosis research 20020715

• Effective information transfer from the alpha 1b-adrenoceptor to Galpha 11 requires both beta/gamma interactions and an aromatic group four amino acids from the C terminus of the G protein.

  The Journal of biological chemistry 20020712

• G350 of Escherichia coli RNase P RNA contributes to Mg2+ binding near the active site of the enzyme.

  Gene 20020710

• The death domain of NF-kappa B1 p105 is essential for signal-induced p105 proteolysis.

  The Journal of biological chemistry 20020705

• Cyclic guanosine 5' monophosphate (GMP) prevents expression of neuronal nitric oxide synthase and apoptosis in motor neurons deprived of trophic factors in rats.

  Neuroscience letters 20020705

• A1 adenosine receptor activation induces ventriculomegaly and white matter loss.

  Neuroreport 20020702

• RhoA exerts a permissive effect on volume-regulated anion channels in vascular endothelial cells.

  American journal of physiology. Cell physiology 20020701

• Characterization of the diarylether sulfonylester (-)-(R)-3-(2-hydroxymethylindanyl-4-oxy)phenyl-4,4,4-trifluoro-1-sulfonate (BAY 38-7271) as a potent cannabinoid receptor agonist with neuroprotective properties.

  The Journal of pharmacology and experimental therapeutics 20020701

• 8-Carboxamidocyclazocine: a long-acting, novel benzomorphan.

  The Journal of pharmacology and experimental therapeutics 20020701

• Presynaptic muscarinic M(2)-receptor-mediated inhibition of N-type Ca(2+) channels in cultured sphenopalatine ganglion: direct evidence for acetylcholine inhibition of cerebral nitrergic neurogenic vasodilation.

  The Journal of pharmacology and experimental therapeutics 20020701

• Crystal structures of free, IMP-, and GMP-bound Escherichia coli hypoxanthine phosphoribosyltransferase.

  Protein science : a publication of the Protein Society 20020701

• Regulated nuclear targeting of cauliflower mosaic virus.

  The Journal of general virology 20020701

• Effects of phenobarbital on DNA methylation in GC-rich regions of hepatic DNA from mice that exhibit different levels of susceptibility to liver tumorigenesis.

  Toxicological sciences : an official journal of the Society of Toxicology 20020701

• Synthesis, characterization and application of two nucleoside triphosphate analogues, GTPgammaNH(2) and GTPgammaF.

  European journal of biochemistry 20020701

• Nitric oxide as an anterograde neurotransmitter in the trigeminal motor pool.

  Journal of neurophysiology 20020701

• Intravenous ribavirin treatment for severe adenovirus disease in immunocompromised children.

  Pediatrics 20020701

• Similarities and differences in the coupling of human beta1- and beta2-adrenoceptors to Gs(alpha) splice variants.

  Biochemical pharmacology 20020701

• P2Y(1) and P2Y(2) receptors are coupled to the NO/cGMP pathway to vasodilate the rat arterial mesenteric bed.

  British journal of pharmacology 20020701

• Stimulation by antipsychotic agents of mitogen-activated protein kinase (MAPK) coupled to cloned, human (h)serotonin (5-HT)(1A) receptors.

  Psychopharmacology 20020701

• Gene expression profiling of Escherichia coli growth transitions: an expanded stringent response model.

  Molecular microbiology 20020701

• Clustering of nucleobases with alkali metals studied by electrospray ionization tandem mass spectrometry: implications for mechanisms of multistrand DNA stabilization.

  Journal of mass spectrometry : JMS 20020701

• DNA hypermethylation status of multiple genes in prostate adenocarcinomas.

  Japanese journal of cancer research : Gann 20020701

• Regulation of the gadd45beta promoter by NF-kappaB.

  DNA and cell biology 20020701

• Dissection of a metal-ion-mediated conformational change in Tetrahymena ribozyme catalysis.

  RNA (New York, N.Y.) 20020701

• Carbon monoxide regulates blood pressure cooperatively with nitric oxide in hypertensive rats.

  Heart and vessels 20020701

• Aging alters in a region-specific manner serotonin transporter sites and 5-HT(1A) receptor-G protein interactions in hamster brain.

  Neuropharmacology 20020701

• The stringent response genes relA and spoT are important for Escherichia coil biofilms under slow-growth conditions.

  Canadian journal of microbiology 20020701

• Guanosine 5'-diphosphate 3'-diphosphate (ppGpp) synthetic activities on Escherichia coli SpoT domains.

  Bioscience, biotechnology, and biochemistry 20020701

• Glutamate uptake in cultured astrocytes depends on age: a study about the effect of guanosine and the sensitivity to oxidative stress induced by H(2)O(2).

  Mechanisms of ageing and development 20020701

• Inhibitory effects of opioids on voltage-dependent Ca(2+) channels and catecholamine secretion in cultured porcine adrenal chromaffin cells.

  Brain research 20020628

• Molecular recognition by the Candida albicans group I intron: tertiary interactions with an imino G.A pair facilitate binding of the 5' exon and lower the KM for guanosine.

  Biochemistry 20020625

• The 7472insC mitochondrial DNA mutation impairs the synthesis and extent of aminoacylation of tRNASer(UCN) but not its structure or rate of turnover.

  The Journal of biological chemistry 20020621

• Synthesis and structure-activity relationships of amide and hydrazide analogues of the cannabinoid CB(1) receptor antagonist N-(piperidinyl)- 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716).

  Journal of medicinal chemistry 20020620

• Effects of morphine withdrawal on micro-opioid receptor-stimulated guanylyl 5'-[gamma-[35S]thio]-triphosphate autoradiography in rat brain.

  European journal of pharmacology 20020620

• Ultrafast decay of electronically excited singlet cytosine via a pi,pi* to n(O),pi* state switch.

  Journal of the American Chemical Society 20020619

• The 'cap-binding slot' of an mRNA cap-binding protein: quantitative effects of aromatic side chain choice in the double-stacking sandwich with cap.

  Biochemistry 20020618

• L-Arginine/nitric oxide pathway in chronic tension-type headache: relation with serotonin content and secretion and glutamate content.

  Journal of the neurological sciences 20020615

• Dehydroepiandrosterone activates endothelial cell nitric-oxide synthase by a specific plasma membrane receptor coupled to Galpha(i2,3).

  The Journal of biological chemistry 20020614

• The immune modulator FTY720 targets sphingosine 1-phosphate receptors.

  The Journal of biological chemistry 20020614

• Hypocretin stimulates [(35)S]GTP gamma S binding in Hcrtr 2-transfected cell lines and in brain homogenate.

  Biochemical and biophysical research communications 20020614

• Serological identification and expression analysis of gastric cancer-associated genes.

  British journal of cancer 20020605

• 2-Amino-alpha-2'-deoxyadenosine increased duplex stability of methoxyethylphosphoramidate alpha-oligodeoxynucleotides with RNA target.

  Bioorganic & medicinal chemistry letters 20020603

• Purine nucleoside phosphorylase from Cellulomonas sp.: physicochemical properties and binding of substrates determined by ligand-dependent enhancement of enzyme intrinsic fluorescence, and by protective effects of ligands on thermal inactivation of the enzyme.

  Biochimica et biophysica acta 20020603

• Quantification of the influence of mycophenolic acid on the release of endothelial adhesion molecules.

  Clinica chimica acta; international journal of clinical chemistry 20020601

• Vasodilatory effect of ghrelin, an endogenous peptide from the stomach.

  Journal of cardiovascular pharmacology 20020601

• Sigma receptors inhibit high-voltage-activated calcium channels in rat sympathetic and parasympathetic neurons.

  Journal of neurophysiology 20020601

• Agonists activate Gi1 alpha or Gi2 alpha fused to the human mu opioid receptor differently.

  Journal of neurochemistry 20020601

• Decreased G-protein coupling of serotonin 5-HT(1A) receptors in the brain of 5-HT(1B) knockout mouse.

  Neuropharmacology 20020601

• Regulation of transcription of the Dnmt1 gene by Sp1 and Sp3 zinc finger proteins.

  European journal of biochemistry 20020601

• Intraluminal gene transfer of endothelial cell-nitric oxide synthase suppresses intimal hyperplasia of vein grafts in cholesterol-fed rabbit: a limited biological effect as a result of the loss of medial smooth muscle cells.

  Surgery 20020601

• Linkage disequilibrium between the androgen receptor gene CAG and GGC repeats in the African-American population.

  Current urology reports 20020601

• Pharmacological comparison of a recombinant CB1 cannabinoid receptor with its G(alpha 16) fusion product.

  Journal of biomolecular screening 20020601

• Regulation of kynurenic acid synthesis in C6 glioma cells.

  Journal of neuroscience research 20020601

• Structure-activity relationship and signal transduction of gamma-MSH peptides in GH3 cells: further evidence for a new melanocortin receptor.

  Peptides 20020601

• Repeated treatment with antidepressants differentially alters 5-HT1A agonist-stimulated [35S]GTP gamma S binding in rat brain regions.

  Neuropharmacology 20020601

• Highly immunostimulatory CpG-free oligodeoxynucleotides for activation of human leukocytes.

  Antisense & nucleic acid drug development 20020601

• Role of adenosine receptors in spinal G-protein activation after peripheral nerve injury.

  Anesthesiology 20020601

• Separation of Trp-Arg and Arg-Trp using G-quartet-forming DNA oligonucleotides in open-tubular capillary electrochromatography.

  Electrophoresis 20020601

• Guanosine enhances glutamate uptake in brain cortical slices at normal and excitotoxic conditions.

  Cellular and molecular neurobiology 20020601

• KF26777 (2-(4-bromophenyl)-7,8-dihydro-4-propyl-1H-imidazo[2,1-i]purin-5(4H)-one dihydrochloride), a new potent and selective adenosine A3 receptor antagonist.

  European journal of pharmacology 20020531

• Identification by site-directed mutagenesis of residues involved in ligand recognition and activation of the human A3 adenosine receptor.

  The Journal of biological chemistry 20020524

• The A167Y mutation converts the herpes simplex virus type 1 thymidine kinase into a guanosine analogue kinase.

  Biochemistry 20020521

• 'Fleximers'. Design and synthesis of a new class of novel shape-modified nucleosides(1).

  The Journal of organic chemistry 20020517

• Effects of [(pF)Phe(4)]nociceptin/orphanin FQ-(1-13)NH(2) on GTPgamma(35)S binding and cAMP formation in Chinese hamster ovary cells expressing the human nociceptin/orphanin FQ receptor.

  European journal of pharmacology 20020517

• Global genome repair of 8-oxoG in hamster cells requires a functional CSB gene product.

  Oncogene 20020516

• An impedance study of the adsorption of nucleic acid bases at glassy carbon electrodes.

  Bioelectrochemistry (Amsterdam, Netherlands) 20020515

• Role of oxidative DNA damage caused by carbon tetrachloride-induced liver injury -- enhancement of MeIQ-induced glutathione S-transferase placental form-positive foci in rats.

  Cancer letters 20020508

• Gel-like lyomesophases formed in organic solvents by self-assembled guanine ribbons.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20020503

• A voltage-independent K+ conductance activated by cell swelling in Ehrlich cells is modulated by a G-protein-mediated process.

  Biochimica et biophysica acta 20020503

• Biochemical characterisation of newly developed beta-etorphine and beta-dihydroetorphine derivatives.

  European journal of pharmacology 20020503

• Differential regulation of 5-HT1A receptor-G protein interactions in brain following chronic antidepressant administration.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20020501

• On the role of phosphatase in regulation of cardiac L-type calcium current by cyclic GMP.

  The Journal of pharmacology and experimental therapeutics 20020501

• Agonist, antagonist, and inverse agonist characteristics of TIPP (H-Tyr-Tic-Phe-Phe-OH), a selective delta-opioid receptor ligand.

  The Journal of pharmacology and experimental therapeutics 20020501

• Allosteric modulation of muscarinic receptor signaling: alcuronium-induced conversion of pilocarpine from an agonist into an antagonist.

  The Journal of pharmacology and experimental therapeutics 20020501

• GTP-induced membrane binding and ion channel activity of annexin VI: is annexin VI a GTP biosensor?

  Biophysical journal 20020501

• Golgi apparatus dynamics during mouse oocyte in vitro maturation: effect of the membrane trafficking inhibitor brefeldin A.

  Biology of reproduction 20020501

• Mechanisms of apoptosis induced by purine nucleosides in astrocytes.

  Glia 20020501

• A potential role for AMP-activated protein kinase in meiotic induction in mouse oocytes.

  Developmental biology 20020501

• Identification of the metal ion binding site on an RNA motif from hammerhead ribozymes using (15)N NMR spectroscopy.

  Journal of the American Chemical Society 20020501

• Formation of transient intermediates in low-temperature photosensitized oxidation of an 8-(13)C-guanosine derivative.

  Journal of the American Chemical Society 20020501

• Phosphodiester CpG oligonucleotides as adjuvants: polyguanosine runs enhance cellular uptake and improve immunostimulative activity of phosphodiester CpG oligonucleotides in vitro and in vivo.

  Immunology 20020501

• Optimizing prostate cancer suicide gene therapy using herpes simplex virus thymidine kinase active site variants.

  Human gene therapy 20020501

• 2[125I]Iodomelatonin binding and interaction with beta-adrenergic signaling in chick heart/coronary artery physiology.

  Journal of pineal research 20020501

• Nucleoside monophosphates recognition using macrocyclic polyamine bonded phase in capillary electrochromatography.

  Electrophoresis 20020501

• Concurrent analysis of nucleoside reverse transcriptase inhibitors in a pool of endogenous nucleosides by short-end injection-capillary electrochromatography on a beta-cyclodextrin-bonded stationary phase.

  Electrophoresis 20020501

• Pharmacological identification of inward current evoked by dopamine in rat subthalamic neurons in vitro.

  Neuropharmacology 20020501

• Evidence for protean agonism of RX 831003 at alpha 2A-adrenoceptors by co-expression with different G alpha protein subunits.

  Neuropharmacology 20020501

• Age-dependent modulation of NF-kappaB expression in rat adrenal gland.

  Mechanisms of ageing and development 20020501

• The atrial natriuretic peptide as a regulator of Kupffer cell functions.

  Shock (Augusta, Ga.) 20020501

• Characteristics of Na(+)-dependent intestinal nucleoside transport in the pig.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20020501

• Effect of ethanol self-administration on mu- and delta-opioid receptor-mediated G-protein activity.

  Alcoholism, clinical and experimental research 20020501

• Adenosine inhibits calcium channel currents via A1 receptors on salamander retinal ganglion cells in a mini-slice preparation.

  Journal of neurochemistry 20020501

• Calf spleen purine nucleoside phosphorylase: complex kinetic mechanism, hydrolysis of 7-methylguanosine, and oligomeric state in solution.

  Biochimica et biophysica acta 20020429

• Involvement of DNA polymerase beta in protection against the cytotoxicity of oxidative DNA damage.

  DNA repair 20020429

• Interaction of the Rho-ADP-ribosylating C3 exoenzyme with RalA.

  The Journal of biological chemistry 20020426

• Influence of gene action across different time scales on behavior.

  Science (New York, N.Y.) 20020426

• Translocation of pleckstrin requires its phosphorylation and newly formed ligands.

  Biochemical and biophysical research communications 20020426

• 5'-Deoxy congeners of 9-(3-amido-3-deoxy-beta-D-xylofuranosyl)-N(6)-cyclopentyladenine: new adenosine A(1) receptor antagonists and inverse agonists.

  Journal of medicinal chemistry 20020425

• Theoretical study on the stability of N-glycosyl bonds: why does N7-platination not promote depurination?

  Journal of the American Chemical Society 20020424

• Role of T7 RNA polymerase His784 in start site selection and initial transcription.

  Biochemistry 20020423

• Insights into the molecular mechanism of inhibition and drug resistance for HIV-1 RT with carbovir triphosphate.

  Biochemistry 20020423

• Self-assembly of human MxA GTPase into highly ordered dynamin-like oligomers.

  The Journal of biological chemistry 20020419

• Low-temperature photosensitized oxidation of a guanosine derivative and formation of an imidazole ring-opened product.

  Journal of the American Chemical Society 20020417

• Creation of a genetic system for analysis of the phagocyte respiratory burst: high-level reconstitution of the NADPH oxidase in a nonhematopoietic system.

  Blood 20020415

• Role of cyclic nucleotides in ischemia and reperfusion injury of canine livers.

  Transplantation 20020415

• Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists.

  Science (New York, N.Y.) 20020412

• Nicotine-modulated formation of spiroiminodihydantoin nucleoside via 8-oxo-7,8-dihydro-2'-deoxyguanosine in 2'-deoxyguanosine-hypochlorous acid reaction.

  FEBS letters 20020410

• Heterotrimeric G-proteins activate Cl- channels through stimulation of a cyclooxygenase-dependent pathway in a model liver cell line.

  The Journal of biological chemistry 20020405

• Kinetics of hydrolysis of 8-(arylamino)-2'-deoxyguanosines.

  The Journal of organic chemistry 20020405

• Ophidian envenomation strategies and the role of purines.

  Toxicon : official journal of the International Society on Toxinology 20020401

• Activation of nonspecific cytotoxic cells (NCC) with synthetic oligodeoxynucleotides and bacterial genomic DNA: binding, specificity and identification of unique immunostimulatory motifs.

  Developmental and comparative immunology 20020401

• Alterations of purine and pyrimidine nucleotide contents in rat corticoencephalic cell cultures following metabolic damage and treatment with openers and blockers of ATP-sensitive potassium channels.

  Neurochemistry international 20020401

• Differential modulation of phospholipase D and phosphatidate phosphohydrolase during aging in rat cerebral cortex synaptosomes.

  Experimental gerontology 20020401

• The enantiomers of carbocyclic 5'-norguanosine: activity towards Epstein-Barr virus.

  Bioorganic & medicinal chemistry 20020401

• Temporal pattern of herpes simplex virus type 1 infection and cell death in the mouse brain stem: influence of guanosine nucleoside analogues.

  Journal of virological methods 20020401

• Sustained norepinephrine contraction in the rat portal vein is lost when Ca(2+) is replaced with Sr(2+).

  American journal of physiology. Cell physiology 20020401

• Actions of a novel synthetic natriuretic peptide on hemodynamics and ventricular function in the dog.

  American journal of physiology. Regulatory, integrative and comparative physiology 20020401

• Enteroinvasive bacteria alter barrier and transport properties of human intestinal epithelium: role of iNOS and COX-2.

  Gastroenterology 20020401

• Properties of Na(+)-dependent nucleoside transport in the proximal and distal small intestine of cows.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20020401

• Effects of age, postmortem delay and storage time on receptor-mediated activation of G-proteins in human brain.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20020401

• ARNO but not cytohesin-1 translocation is phosphatidylinositol 3-kinase-dependent in HL-60 cells.

  Journal of leukocyte biology 20020401

• Heterotrimeric G protein signaling: role in asthma and allergic inflammation.

  The Journal of allergy and clinical immunology 20020401

• Biochemical markers of the L-arginine-nitric oxide pathway in the aqueous humour in glaucoma patients.

  Acta ophthalmologica Scandinavica 20020401

• A direct inhibitory action of prostaglandins upon ACTH secretion at the late stages of the secretory pathway of AtT-20 cells.

  British journal of pharmacology 20020401

• Structure of wyosine, the condensed tricyclic nucleoside of torula yeast phenylalanine transfer ribonucleic acid.

  Chemical & pharmaceutical bulletin 20020401

• Modulation of cytotoxicity of benzamide riboside by expression of NMN adenylyltransferase.

  Current medicinal chemistry 20020401

• Potential mechanisms of benzamide riboside mediated cell death.

  Current medicinal chemistry 20020401

• A two-component regulator induces the transmission phenotype of stationary-phase Legionella pneumophila.

  Molecular microbiology 20020401

• Genetic and antigenic analysis of the first A/New Caledonia/20/99-like H1N1 influenza isolates reported in the Americas.

  Emerging infectious diseases 20020401

• Biomolecular electronic devices based on self-organized deoxyguanosine nanocrystals.

  Annals of the New York Academy of Sciences 20020401

• Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation.

  Molecular cell 20020401

• Hypermethylation of the cap structure of both yeast snRNAs and snoRNAs requires a conserved methyltransferase that is localized to the nucleolus.

  Molecular cell 20020401

• Damage control of DNA in nucleosome core particles: when a histone's loving, protective embrace is just not good enough.

  Chemistry & biology 20020401

• Oxidative charge transport through DNA in nucleosome core particles.

  Chemistry & biology 20020401

• Solution structure of an RNA fragment with the P7/P9.0 region and the 3'-terminal guanosine of the tetrahymena group I intron.

  RNA (New York, N.Y.) 20020401

• Phosphodiesterase inhibitors cause relaxation of the internal anal sphincter in vitro.

  Diseases of the colon and rectum 20020401

• Elevated nasal mucosal G protein levels and histamine receptor affinity in a guinea pig model of nasal hyperresponsiveness.

  International archives of allergy and immunology 20020401

• Receptor-mediated modulation of avian caecal muscle contraction by melatonin: role of tyrosine protein kinase.

  Journal of pineal research 20020401

• A DNA-electrochemical biosensor for screening environmental damage caused by s-triazine derivatives.

  Analytical and bioanalytical chemistry 20020401

• [The optimization of guanosine fermentation based on process parameter correlation analysis].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20020401

• Role of the conserved DRY motif on G protein activation of rat angiotensin II receptor type 1A.

  Biochemical and biophysical research communications 20020329

• Constitutively active melatonin MT(1) receptors in male rat caudal arteries.

  European journal of pharmacology 20020329

• Organometallic ruthenium(II) diamine anticancer complexes: arene-nucleobase stacking and stereospecific hydrogen-bonding in guanine adducts.

  Journal of the American Chemical Society 20020327

• Hypocretin-1 activates G proteins in arousal-related brainstem nuclei of rat.

  Neuroreport 20020325

• Novel, not adenylyl cyclase-coupled cannabinoid binding site in cerebellum of mice.

  Biochemical and biophysical research communications 20020322

• Delta opioid receptor localization in the rat cerebellum.

  Brain research 20020322

• Antiproliferative activity of G-quartet-forming oligonucleotides with backbone and sugar modifications.

  Biochemistry 20020319

• Biochemical and functional characterization of recombinant Rhodnius prolixus platelet aggregation inhibitor 1 as a novel lipocalin with high affinity for adenosine diphosphate and other adenine nucleotides.

  Biochemistry 20020319

• Nociceptin/orphanin FQ and opioid receptor-like receptor mRNA expression in dopamine systems.

  The Journal of comparative neurology 20020318

• Interaction of human nuclear topoisomerase I with guanosine quartet-forming and guanosine-rich single-stranded DNA and RNA oligonucleotides.

  The Journal of biological chemistry 20020315

• Characterization of two unusual guanylyl cyclases from dictyostelium.

  The Journal of biological chemistry 20020315

• Activation mechanism of Gi and Go by reactive oxygen species.

  The Journal of biological chemistry 20020315

• Relationship between the self-splicing activity and the solidity of the master domain of the Tetrahymena group I ribozyme.

  Biochemical and biophysical research communications 20020315

• T-226296: a novel, orally active and selective melanin-concentrating hormone receptor antagonist.

  European journal of pharmacology 20020308

• Mitochondrial DNA repair of oxidative damage in mammalian cells.

  Gene 20020306

• Evidence for synergy between alpha(2)-adrenergic and nonadrenergic mechanisms in central blood pressure regulation.

  Circulation 20020305

• Identification of structural features in the G-protein regulatory motif required for regulation of heterotrimeric G-proteins.

  The Journal of biological chemistry 20020301

• Phosphatidic acid modulates G protein regulation of phospholipase C-beta1 activity in membranes.

  Cellular signalling 20020301

• Cyclic AMP increases rat inhibitor of apoptosis protein (RIAP1) mRNA in renal mesangial cells.

  Kidney international 20020301

• A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid.

  The Journal of pharmacology and experimental therapeutics 20020301

• Determinants of ligand selectivity at the kappa-receptor based on the structure of the orphanin FQ receptor.

  The Journal of pharmacology and experimental therapeutics 20020301

• Beta(3)-mediated engulfment of apoptotic tumor cells by dendritic cells is dependent on CAMKII: inhibition by HIV-1 Tat.

  Journal of leukocyte biology 20020301

• Chronic fluoxetine treatment selectively uncouples raphe 5-HT(1A) receptors as measured by [(35)S]-GTP gamma S autoradiography.

  British journal of pharmacology 20020301

• Dissociation of the store-operated calcium current I(CRAC) and the Mg-nucleotide-regulated metal ion current MagNuM.

  The Journal of physiology 20020301

• Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy.

  Neurobiology of disease 20020301

• Pharmacological characterization of the ATP-dependent low K(m) guanosine 3',5'-cyclic monophosphate (cGMP) transporter in human erythrocytes.

  Biochemical pharmacology 20020301

• Enhancement of cellular adenosine triphosphate levels in PC12 cells by extracellular adenosine.

  Biological & pharmaceutical bulletin 20020301

• The Sinorhizobium meliloti stringent response affects multiple aspects of symbiosis.

  Molecular microbiology 20020301

• Regulators of GTP-binding proteins cause morphological changes in the vacuole system of the filamentous fungus, Pisolithus tinctorius.

  Cell motility and the cytoskeleton 20020301

• Sodium dependence of nitrofurantoin active transport across mammary epithelia and effects of dipyridamole, nucleosides, and nucleobases.

  Pharmaceutical research 20020301

• Characterisation of the non-peptide nociceptin receptor agonist, Ro64-6198 in Chinese hamster ovary cells expressing recombinant human nociceptin receptors.

  Life sciences 20020301

• Calcium influx into dendrites of the leech Retzius neuron evoked by 5-hydroxytryptamine.

  Cell calcium 20020301

• 2[125I]Iodomelatonin binding sites in guinea pig platelets.

  Journal of pineal research 20020301

• Molecular mechanism of DApd/DXG against zidovudine- and lamivudine- drug resistant mutants: a molecular modelling approach.

  Antiviral chemistry & chemotherapy 20020301

• Melatonin.

  Dialogues in clinical neuroscience 20020301

• Identification of an active site ligand for a group I ribozyme catalytic metal ion.

  Biochemistry 20020226

• Mechanism of ADP ribosylation factor-stimulated phosphatidylinositol 4,5-bisphosphate synthesis in HL60 cells.

  The Journal of biological chemistry 20020222

• Guanine based purines inhibit [(3)H]glutamate and [(3)H]AMPA binding at postsynaptic densities from cerebral cortex of rats.

  Brain research 20020222

• Spiroiminodihydantoin is a major product in the photooxidation of 2'-deoxyguanosine by the triplet states and oxyl radicals generated from hydroxyacetophenone photolysis and dioxetane thermolysis.

  Organic letters 20020221

• Categorization and characterization of transcript-confirmed constitutively and alternatively spliced introns and exons from human.

  Human molecular genetics 20020215

• DOI, a 5-HT2 receptor agonist, induces renal vasodilation via nitric oxide in anesthetized dogs.

  European journal of pharmacology 20020215

• Identification and properties of a Gs protein in catfish liver membranes.

  General and comparative endocrinology 20020215

• Regulation of cyclic AMP in rat pulmonary microvascular endothelial cells by rolipram-sensitive cyclic AMP phosphodiesterase (PDE4).

  Biochemical pharmacology 20020215

• Distinct regions of C-terminus of the high affinity neurotensin receptor mediate the functional coupling with pertussis toxin sensitive and insensitive G-proteins.

  FEBS letters 20020213

• Agonist-induced force enhancement: the role of isoforms and phosphorylation of the myosin-targeting subunit of myosin light chain phosphatase.

  The Journal of biological chemistry 20020208

• Involvement of monoaminergic system in the antidepressant-like effect of the hydroalcoholic extract of Siphocampylus verticillatus.

  Life sciences 20020208

• A single glycine mutation in the equilibrative nucleoside transporter gene, hENT1, alters nucleoside transport activity and sensitivity to nitrobenzylthioinosine.

  Biochemistry 20020205

• Pharmacological characterisation of the goldfish somatostatin sst5 receptor.

  European journal of pharmacology 20020202

• A novel binding protein composed of homophilic tetramer exhibits unique properties for the small GTPase Rab5.

  The Journal of biological chemistry 20020201

• Reciprocal mutations of highly conserved residues in transmembrane helices 2 and 7 of the alpha(2A)-adrenoceptor restore agonist activation of G(i1)alpha.

  Cellular signalling 20020201

• Impaired parasympathetic heart rate control in mice with a reduction of functional G protein betagamma-subunits.

  American journal of physiology. Heart and circulatory physiology 20020201

• Regulation of K(ATP) channels by P(2Y) purinoceptors coupled to PIP(2) metabolism in guinea pig ventricular cells.

  American journal of physiology. Heart and circulatory physiology 20020201

• Blood flow-dependent changes in renal interstitial guanosine 3',5'-cyclic monophosphate in rabbits.

  American journal of physiology. Renal physiology 20020201

• Cell-permeable ceramides preferentially inhibit coated vesicle formation and exocytosis in Chinese hamster ovary compared with Madin-Darby canine kidney cells by preventing the membrane association of ADP-ribosylation factor.

  The Biochemical journal 20020201

• Reactive oxygen species (H(2)O(2)): effects on the gallbladder muscle of guinea pigs.

  American journal of physiology. Gastrointestinal and liver physiology 20020201

• In vitro high-throughput screening assay for modulators of transcription.

  Analytical biochemistry 20020201

• Detection of glucagon-dependent GTPgammaS binding in high-throughput format.

  Analytical biochemistry 20020201

• TGFbeta2 mediates rapid inhibition of calcium influx in identified cholinergic basal forebrain neurons.

  Biochemical and biophysical research communications 20020201

• Loss of stimulatory effect of guanosine triphosphate on [(35)S]GTPgammaS binding correlates with Alzheimer's disease neurofibrillary pathology in entorhinal cortex and CA1 hippocampal subfield.

  Journal of neuroscience research 20020201

• Endothelial cell compatibility of azithromycin and erythromycin.

  The Journal of antimicrobial chemotherapy 20020201

• Imprinting of nucleotide and monosaccharide recognition sites in acrylamidephenylboronic acid-acrylamide copolymer membranes associated with electronic transducers.

  Analytical chemistry 20020201

• The human histamine H2-receptor couples more efficiently to Sf9 insect cell Gs-proteins than to insect cell Gq-proteins: limitations of Sf9 cells for the analysis of receptor/Gq-protein coupling.

  Journal of neurochemistry 20020201

• Differential scanning calorimetric study of the binding of the primary water of hydration to nucleosides.

  Journal of biomolecular structure & dynamics 20020201

• Comparison of nitric oxide donors in lowering intraocular pressure in rabbits: role of cyclic GMP.

  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20020201

• Nitric oxide-induced signalling in rat lacrimal acinar cells.

  Acta physiologica Scandinavica 20020201

• Specific [(3)H]-guanosine binding sites in rat brain membranes.

  British journal of pharmacology 20020201

• Pharmacological characterization of the chemokine receptor, CCR5.

  British journal of pharmacology 20020201

• Capillary electrophoresis for detection of inherited disorders of purine and pyrimidine metabolism: a selective approach.

  Electrophoresis 20020201

• Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger.

  Current topics in medicinal chemistry 20020201

• Altered modulation of soluble guanylate cyclase in lymphocytes from patients with liver disease.

  Journal of molecular medicine (Berlin, Germany) 20020201

• Pathways followed by ricin and Shiga toxin into cells.

  Histochemistry and cell biology 20020201

• Analysis of cell damage in Helicobacter pylori-associated gastritis.

  Pathology international 20020201

• VIP and PACAP inhibit L-, N- and P/Q-type Ca2+ channels of parasympathetic neurons in a voltage independent manner.

  The Bulletin of Tokyo Dental College 20020201

• Dietary vitamin B6 suppresses colon tumorigenesis, 8-hydroxyguanosine, 4-hydroxynonenal, and inducible nitric oxide synthase protein in azoxymethane-treated mice.

  Journal of nutritional science and vitaminology 20020201

• Preparation of 2'-O-[(Triisopropylsilyl)oxy]methyl-protected ribonucleosides.

  Current protocols in nucleic acid chemistry 20020201

• Related affinities of different mononucleosides and mono nucleotides towards Pr (III) and Nd (III) in aquated organic solvents explored through 4f-4f transition spectral analysis.

  Indian journal of biochemistry & biophysics 20020201

• The 5-hydroxytryptamine(4a) receptor is palmitoylated at two different sites, and acylation is critically involved in regulation of receptor constitutive activity.

  The Journal of biological chemistry 20020125

• The efflux of purine nucleobases and nucleosides from the rat brain.

  Neuroscience letters 20020125

• The effect of stimulators and blockers of adrenergic receptors on LH secretion and cyclic nucleotide (cAMP and cGMP) production by porcine pituitary cells in vitro.

  Animal reproduction science 20020123

• Open and closed conformation of the E. coli purine nucleoside phosphorylase active center and implications for the catalytic mechanism.

  Journal of molecular biology 20020118

• 2,5'-Disubstituted adenosine derivatives: evaluation of selectivity and efficacy for the adenosine A(1), A(2A), and A(3) receptor.

  Journal of medicinal chemistry 20020117

• Phosphorylation states of Cdc42 and RhoA regulate their interactions with Rho GDP dissociation inhibitor and their extraction from biological membranes.

  The Biochemical journal 20020115

• Two glutamate residues, Glu 208 alpha and Glu 197 beta, are crucial for phosphorylation and dephosphorylation of the active-site histidine residue in succinyl-CoA synthetase.

  Biochemistry 20020115

• Efficiency of incision of an AP site within clustered DNA damage by the major human AP endonuclease.

  Biochemistry 20020115

• Sensitivity of HaCat keratinocytes to diabetogenic toxins.

  Biochemical pharmacology 20020115

• Kinetic analysis of M2 muscarinic receptor activation of Gi in Sf9 insect cell membranes.

  The Journal of biological chemistry 20020111

• Regulation of adenylyl cyclases by a region outside the minimally functional cytoplasmic domains.

  The Journal of biological chemistry 20020111

• Synthesis and biological activities of conformationally restricted cyclopentenyl-glutamate analogues.

  The Journal of organic chemistry 20020111

• Differential expression of the isoforms for the monocyte chemoattractant protein-1 receptor, CCR2, in monocytes.

  Biochemical and biophysical research communications 20020111

• UV resonance Raman and circular dichroism studies of a DNA duplex containing an A(3)T(3) tract: evidence for a premelting transition and three-centered H-bonds.

  Biochemistry 20020108

• A GPR-protein interaction surface of Gi(alpha): implications for the mechanism of GDP-release inhibition.

  Biochemistry 20020108

• Functional interaction between bovine rhodopsin and G protein transducin.

  The Journal of biological chemistry 20020104

• Direct observation of a cytosine analogue that forms five hydrogen bonds to guanosine: guanidino G-clamp.

  Angewandte Chemie (International ed. in English) 20020104

• G(alpha)(i) controls the gating of the G protein-activated K(+) channel, GIRK.

  Neuron 20020103

• Functional characterization of p115 RhoGEF.

  Methods in enzymology 20020101

• BIG1 and BIG2: brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors.

  Methods in enzymology 20020101

• Relationship between rate and extent of G protein activation: comparison between full and partial opioid agonists.

  The Journal of pharmacology and experimental therapeutics 20020101

• Molecular basis of differences in (-)(trans)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidiny)-cyclohexyl]benzeneacetamide-induced desensitization and phosphorylation between human and rat kappa-opioid receptors expressed in Chinese hamster ovary cells.

  Molecular pharmacology 20020101

• Differences in signal transduction of two 5-HT4 receptor splice variants: compound specificity and dual coupling with Galphas- and Galphai/o-proteins.

  Molecular pharmacology 20020101

• The FANCG Fanconi anemia protein interacts with CYP2E1: possible role in protection against oxidative DNA damage.

  Carcinogenesis 20020101

• 12-hydroxyeicosatetrenoate (12-HETE) attenuates AMPA receptor-mediated neurotoxicity: evidence for a G-protein-coupled HETE receptor.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20020101

• Role of G protein beta gamma complex in receptor-G protein interaction.

  Methods in enzymology 20020101

• Analysis of signal transfer from receptor to Go/Gi in different membrane environments and receptor-independent activators of brain G protein.

  Methods in enzymology 20020101

• Analysis of G protein activation in Sf9 and mammalian cells by agonist-promoted [35S]GTP gamma S binding.

  Methods in enzymology 20020101

• Fluorescence approaches to study G protein mechanisms.

  Methods in enzymology 20020101

• Neuroanatomical localization of receptor-activated G proteins in brain.

  Methods in enzymology 20020101

• Development of Gs-selective inhibitory compounds.

  Methods in enzymology 20020101

• Characterization of deamidated G protein subunits.

  Methods in enzymology 20020101

• Protein interaction assays with G proteins.

  Methods in enzymology 20020101

• Assay of RGS protein activity in vitro using purified components.

  Methods in enzymology 20020101

• Dissecting receptor-G protein specificity using G alpha chimeras.

  Methods in enzymology 20020101

• Valacyclovir in the treatment of genital herpes and herpes zoster.

  Expert opinion on pharmacotherapy 20020101

• Chromosome-wide assessment of replication timing for human chromosomes 11q and 21q: disease-related genes in timing-switch regions.

  Human molecular genetics 20020101

• A critical protein kinase C phosphorylation site on the 5-HT(1A) receptor controlling coupling to N-type calcium channels.

  The Journal of physiology 20020101

• Clostridium perfringens alpha-toxin induces rabbit neutrophil adhesion.

  Microbiology (Reading, England) 20020101

• Dioxolane guanosine, the active form of the prodrug diaminopurine dioxolane, is a potent inhibitor of drug-resistant HIV-1 isolates from patients for whom standard nucleoside therapy fails.

  Journal of acquired immune deficiency syndromes (1999) 20020101

• Arachidonic acid release from rat Leydig cells: the involvement of G protein, phospholipase A2 and regulation of cAMP production.

  The Journal of endocrinology 20020101

• Mu and Delta opioid receptors activate the same G proteins in human neuroblastoma SH-SY5Y cells.

  British journal of pharmacology 20020101

• Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals.

  Chemical research in toxicology 20020101

• Involvement of GTP-binding protein in pancreatic cAMP-mediated exocytosis.

  Pflugers Archiv : European journal of physiology 20020101

• Repair of oxidized purines and damaged pyrimidines by E. coli Fpg protein: different roles of proline 2 and lysine 57 residues.

  Environmental and molecular mutagenesis 20020101

• Histamine H3-receptor-mediated [35S]GTP gamma[S] binding: evidence for constitutive activity of the recombinant and native rat and human H3 receptors.

  British journal of pharmacology 20020101

• N-terminal acylation of somatostatin analog with long chain fatty acids enhances its stability and anti-proliferative activity in human breast adenocarcinoma cells.

  Biological & pharmaceutical bulletin 20020101

• A rhodopsin-like protein in the plasma membrane of Silvetia compressa eggs.

  Photochemistry and photobiology 20020101

• H1 and H2 histamine receptors mediate the production of inositol phosphates but not cAMP in human breast epithelial cells.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020101

• Spontaneous release of GDP from Gi proteins and inhibition of adenylyl cyclase in cardiac sarcolemmal membranes.

  Naunyn-Schmiedeberg's archives of pharmacology 20020101

• [Crosslinking of mRNA analog, pUUAGUAUUUAUU derivative with a photoactivated group at the guanosine residue, with human 80S ribosomes].

  Molekuliarnaia biologiia 20020101

• Integration of splicing, transport and translation to achieve mRNA quality control by the nonsense-mediated decay pathway.

  Genome biology 20020101

• Biochemical characteristics of guanine nucleotide binding protein alpha-subunit recombinant protein and three mutants: investigation of a domain motion involved in GDP-GTP exchange.

  Journal of protein chemistry 20020101

• RNA:(guanine-N2) methyltransferases RsmC/RsmD and their homologs revisited--bioinformatic analysis and prediction of the active site based on the uncharacterized Mj0882 protein structure.

  BMC bioinformatics 20020101

• Bench-to-bedside review: genetic influences on meningococcal disease.

  Critical care (London, England) 20020101

• Photoreceptor specific guanylate cyclases in vertebrate phototransduction.

  Molecular and cellular biochemistry 20020101

• Effect of pertussis toxin and N-ethylmaleimide on voltage-dependent and -independent calcium current modulation in serotonergic neurons.

  Neuroscience 20020101

• S111N mutation in the helical domain of human Gs(alpha) reduces its GDP/GTP exchange rate.

  Journal of cellular biochemistry 20020101

• cGMP-dependent protein kinase expression restores contractile function in cultured vascular smooth muscle cells.

  Journal of vascular research 20020101

• [18O]-labeled singlet oxygen as a tool for mechanistic studies of 8-oxo-7,8-dihydroguanine oxidative damage: detection of spiroiminodihydantoin, imidazolone and oxazolone derivatives.

  Biological chemistry 20020101

• Targeting fragile X.

  Genome biology 20020101

• Plasma guanosine 3',5'-cyclic monophosphate and severity of peri/intraventricular haemorrhage in the preterm newborn.

  Acta paediatrica (Oslo, Norway : 1992) 20020101

• ARF-directed guanine-nucleotide-exchange (GEP) proteins.

  Methods in molecular biology (Clifton, N.J.) 20020101

• Prevention and treatment of respiratory syncytial virus bronchiolitis and postbronchiolitic wheezing.

  Respiratory research 20020101

• Quantitative assessment of the use of modified nucleoside triphosphates in expression profiling: differential effects on signal intensities and impacts on expression ratios.

  BMC biotechnology 20020101

• Expression profiling of Drosophila imaginal discs.

  Genome biology 20020101

• Neurotransmitter receptor-mediated activation of G-proteins in brains of suicide victims with mood disorders: selective supersensitivity of alpha(2A)-adrenoceptors.

  Molecular psychiatry 20020101

• [Study of the antiviral mechanism of action of ribavirin in the bovine viral diarrhea virus model].

  Gastroenterologie clinique et biologique 20020101

• Mycophenolic acid and methotrexate inhibit lymphocyte cytokine production via different mechanisms.

  European cytokine network 20020101

• NMDA receptor antagonists ketamine and PCP have direct effects on the dopamine D(2) and serotonin 5-HT(2)receptors-implications for models of schizophrenia.

  Molecular psychiatry 20020101

• Mycophenolic acid inhibits inosine 5'-monophosphate dehydrogenase and suppresses production of pro-inflammatory cytokines, nitric oxide, and LDH in macrophages.

  Cellular immunology 20020101

• Characterization of specific GTP binding sites in C2C12 mouse skeletal muscle cells.

  Journal of muscle research and cell motility 20020101

• Antagonistic property of buprenorphine for putative epsilon-opioid receptor-mediated G-protein activation by beta-endorphin in pons/medulla of the mu-opioid receptor knockout mouse.

  Neuroscience 20020101

• Potentiating effect of mizoribine on the anti-herpes virus activity of acyclovir.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101

• Chemical stability of 2'-deoxy-5-methylisocytidine during oligodeoxynucleotide synthesis and deprotection.

  Nucleosides, nucleotides & nucleic acids 20020101

• Regioselective 1-alkylation of 2'-deoxyguanosine.

  Nucleosides, nucleotides & nucleic acids 20020101

• Group I aptazymes as genetic regulatory switches.

  BMC biotechnology 20020101

• [Free radical oxidation of DNA and its biomarker oxidized guanosine(8-oxodG)].

  Voprosy meditsinskoi khimii 20020101

• Nad-299 antagonises 5-HT-stimulated and spiperone-inhibited [35S]GTPgammaS binding in cloned 5-HT1A receptors.

  Journal of receptor and signal transduction research 20020101

• Synthesis of 2'-deoxy-2'-fluoroguanyl-(3',5')-guanosine.

  Nucleosides, nucleotides & nucleic acids 20020101

• A Drosophila full-length cDNA resource.

  Genome biology 20020101

• The use of receptor G-protein fusion proteins for the study of ligand activity.

  Receptors & channels 20020101

• [Comparative analysis of differentiating and apoptogenic effects of cytidine, thymidine, and guanosine on cells of human erythromyeloleukemic cell line K562].

  Voprosy meditsinskoi khimii 20020101

• Physicochemical analysis of nucleobase-metal interactions.

  Nucleic acids research. Supplement (2001) 20020101

• [Application of tiazofurin in the study of regulation of AMP deaminase in intact malignant cells].

  Glas. Srpska akademija nauka i umetnosti. Odeljenje medicinskih nauka 20020101

• Antimalarial drugs inhibit the acetylcholine-receptor-operated potassium current in atrial myocytes.

  Heart, lung & circulation 20020101

• Effects of the SOD mimic nitroxide 3-carbamoyl-PROXYL on oxidative stress markers and endothelial dysfunction in streptozotocin-induced diabetic rats.

  Experimental and clinical cardiology 20020101

• The proteins of synaptic vesicle membranes are affected during ageing of rat brain.

  Experimental & molecular medicine 20011231

• Regulation of formyl peptide receptor agonist affinity by reconstitution with arrestins and heterotrimeric G proteins.

  The Journal of biological chemistry 20011228

• Insulin stimulates actin comet tails on intracellular GLUT4-containing compartments in differentiated 3T3L1 adipocytes.

  The Journal of biological chemistry 20011228

• Protein phosphatase 2A interacts with and directly dephosphorylates RelA.

  The Journal of biological chemistry 20011221

• Rab3B in human platelet is membrane bound and interacts with Ca(2+)/calmodulin.

  Biochemical and biophysical research communications 20011221

• Rac, a small guanosine triphosphate-binding protein, and p21-activated kinase are activated during platelet spreading on collagen-coated surfaces: roles of integrin alpha(2)beta(1).

  Blood 20011215

• RNAi is antagonized by A-->I hyper-editing.

  EMBO reports 20011215

• Kinetic characterization of enzyme inhibitors using electrospray-ionization mass spectrometry coupled with multiple reaction monitoring.

  Analytical chemistry 20011215

• 6-bromopurine nucleosides as reagents for nucleoside analogue synthesis.

  The Journal of organic chemistry 20011214

• Agonist, antagonist, and inverse agonist properties of antipsychotics at human recombinant 5-HT(1A) receptors expressed in HeLa cells.

  European journal of pharmacology 20011214

• Impaired G protein coupling of the neurotensin receptor 1 by mutations in extracellular loop 3.

  European journal of pharmacology 20011214

• A novel nitroimidazole compound formed during the reaction of peroxynitrite with 2',3',5'-tri-O-acetyl-guanosine.

  Journal of the American Chemical Society 20011212

• Effect of sequence context on O(6)-methylguanine repair and replication in vivo.

  Biochemistry 20011211

• Serine 232 of the alpha(2A)-adrenergic receptor is a protein kinase C-sensitive effector coupling switch.

  Biochemistry 20011211

• trans-4-[4-(Methoxyphenyl)cyclohexyl]-1-arylpiperazines: a new class of potent and selective 5-HT(1A) receptor ligands as conformationally constrained analogues of 4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]-1-arylpiperazines.

  Journal of medicinal chemistry 20011206

• Identification and determination of nucleosides in rat brain microdialysates by liquid chromatography/electrospray tandem mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20011201

• Guanine nucleosides and Jurkat cell death: roles of ATP depletion and accumulation of deoxyribonucleotides.

  American journal of physiology. Cell physiology 20011201

• Mechanisms of modulation of neuronal nicotinic receptors by substance P and OAG.

  American journal of physiology. Cell physiology 20011201

• 6-(4-Benzylpiperazin-1-yl)benzodioxanes as selective ligands at cloned primate dopamine D(4) receptors.

  Bioorganic & medicinal chemistry 20011201

• Colocalization of mu-opioid receptors and activated G-proteins in rat cingulate cortex.

  The Journal of pharmacology and experimental therapeutics 20011201

• Similar apparent constitutive activity of human histamine H(2)-receptor fused to long and short splice variants of G(salpha).

  The Journal of pharmacology and experimental therapeutics 20011201

• N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-nitrophenyl) cyclohexanecarboxamide: a novel pre- and postsynaptic 5-hydroxytryptamine(1A) receptor antagonist active on the lower urinary tract.

  The Journal of pharmacology and experimental therapeutics 20011201

• Activity of 2-substituted lysophosphatidic acid (LPA) analogs at LPA receptors: discovery of a LPA1/LPA3 receptor antagonist.

  Molecular pharmacology 20011201

• Distinct interaction of human and guinea pig histamine H2-receptor with guanidine-type agonists.

  Molecular pharmacology 20011201

• Synergistic effect of urotensin II with serotonin on vascular smooth muscle cell proliferation.

  Journal of hypertension 20011201

• Staying alive.

  Nature reviews. Molecular cell biology 20011201

• RGS14 is a bifunctional regulator of Galphai/o activity that exists in multiple populations in brain.

  Journal of neurochemistry 20011201

• Presence of NK2 binding sites in the rat brain.

  Journal of neurochemistry 20011201

• An overview on functional receptor autoradiography using [35S]GTPgammaS.

  Brain research. Brain research reviews 20011201

• Additional evidence for the cyclic GMP signaling pathway resulting in the photophobic behavior of Stentor coeruleus.

  Photochemistry and photobiology 20011201

• Synthesis of halogen-substituted 3-deazaadenosine and 3-deazaguanosine analogues as potential antitumor/antiviral agents.

  Nucleosides, nucleotides & nucleic acids 20011201

• Characterization of a G protein coupling 'YL' motif of the human VPAC1 receptor, equivalent to the first two amino acids in the 'DRY' motif of the rhodopsin family.

  Journal of molecular neuroscience : MN 20011201

• Toxoplasma gondii: mechanism of the parasitostatic action of 6-thioxanthine.

  Experimental parasitology 20011201

• Dopamine D2 receptor-mediated G-protein activation in rat striatum: functional autoradiography and influence of unilateral 6-hydroxydopamine lesions of the substantia nigra.

  Brain research 20011130

• RGS-PX1, a GAP for GalphaS and sorting nexin in vesicular trafficking.

  Science (New York, N.Y.) 20011130

• In vitro activity of LY393558, an inhibitor of the 5-hydroxytryptamine transporter with 5-HT(1B/1D/2) receptor antagonist properties.

  European journal of pharmacology 20011130

• Anticodon domain methylated nucleosides of yeast tRNA(Phe) are significant recognition determinants in the binding of a phage display selected peptide.

  Biochemistry 20011127

• Over-expression of NCS-1 in AtT-20 cells affects ACTH secretion and storage.

  Molecular and cellular endocrinology 20011126

• Cannabinoid CB(1) receptor expression, activation and detection of endogenous ligand in trabecular meshwork and ciliary process tissues.

  European journal of pharmacology 20011123

• NFkappaB activation is required for the neuroprotective effects of pigment epithelium-derived factor (PEDF) on cerebellar granule neurons.

  The Journal of biological chemistry 20011116

• Inhibition of DNA replication and induction of S phase cell cycle arrest by G-rich oligonucleotides.

  The Journal of biological chemistry 20011116

• Quadruple intercalated G-6 stack: a possible motif in the fold-back structure of the Drosophila centromeric dodeca-satellite?

  Journal of molecular biology 20011116

• Long-term entecavir treatment results in sustained antiviral efficacy and prolonged life span in the woodchuck model of chronic hepatitis infection.

  The Journal of infectious diseases 20011115

• Functional involvement of G8 in the hairpin ribozyme cleavage mechanism.

  The EMBO journal 20011115

• Unique misinsertion specificity of poliota may decrease the mutagenic potential of deaminated cytosines.

  The EMBO journal 20011115

• Reduced phospholipase C-beta activity and isoform expression in the cerebellum of TS65Dn mouse: a model of Down syndrome.

  Journal of neuroscience research 20011115

• Functional role of a conserved motif in TM6 of the rat mu opioid receptor: constitutively active and inactive receptors result from substitutions of Thr6.34(279) with Lys and Asp.

  Biochemistry 20011113

• Augmentation of cardiac contractility mediated by the human beta(3)-adrenergic receptor overexpressed in the hearts of transgenic mice.

  Circulation 20011113

• beta-Arrestin-mediated ADP-ribosylation factor 6 activation and beta 2-adrenergic receptor endocytosis.

  The Journal of biological chemistry 20011109

• Defective Gi protein coupling in two formyl peptide receptor mutants associated with localized juvenile periodontitis.

  The Journal of biological chemistry 20011109

• Structure-activity studies on nociceptin analogues: ORL1 receptor binding and biological activity of cyclic disulfide-containing analogues of nociceptin peptides.

  Journal of medicinal chemistry 20011108

• GTPgammaS regulation of a 12-transmembrane guanylyl cyclase is retained after mutation to an adenylyl cyclase.

  The Journal of biological chemistry 20011102

• Chlorination of guanosine and other nucleosides by hypochlorous acid and myeloperoxidase of activated human neutrophils. Catalysis by nicotine and trimethylamine.

  The Journal of biological chemistry 20011102

• Potent antagonism of 5-HT(3) and 5-HT(6) receptors by olanzapine.

  European journal of pharmacology 20011102

• Formation of 2-chloroinosine from guanosine by treatment of HNO(2) in the presence of NaCl.

  Bioorganic & medicinal chemistry 20011101

• Modulation of N-type Ca2+ currents by A1-adenosine receptor activation in male rat pelvic ganglion neurons.

  The Journal of pharmacology and experimental therapeutics 20011101

• Identification of essential residues involved in the glutamate binding pocket of the group II metabotropic glutamate receptor.

  Molecular pharmacology 20011101

• Activation of inositol 1,4,5-trisphosphate receptor is essential for the opening of mouse TRP5 channels.

  Molecular pharmacology 20011101

• Crystallization and preliminary X-ray diffraction analysis of cytotoxic ribonucleases from bullfrog Rana catesbeiana.

  Acta crystallographica. Section D, Biological crystallography 20011101

• Inhibition of acetylcholine-activated K(+) currents by U73122 is mediated by the inhibition of PIP(2)-channel interaction.

  British journal of pharmacology 20011101

• Augmented oxidative stress of platelets in chronic smokers. Mechanisms of impaired platelet-derived nitric oxide bioactivity and augmented platelet aggregability.

  Journal of the American College of Cardiology 20011101

• Guanine nucleotides and acute renal failure.

  The Journal of clinical investigation 20011101

• Guanosine supplementation reduces apoptosis and protects renal function in the setting of ischemic injury.

  The Journal of clinical investigation 20011101

• Differential activation of the volume-sensitive cation channel TRP12 (OTRPC4) and volume-regulated anion currents in HEK-293 cells.

  Pflugers Archiv : European journal of physiology 20011101

• Immunoexpression of neurofibromin, S-100 protein, and leu-7 and mutation analysis of the NF1 gene at codon 1423 in osteofibrous dysplasia.

  Human pathology 20011101

• Impaired beta-adrenergic signaling pathway in white adipocytes of suckling fa/fa Zucker rats: a defect in receptor coupling.

  International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20011101

• Total parenteral nutrition modulates hormone release by stimulating expression and activity of inducible nitric oxide synthase in rat pancreatic islets.

  Endocrine 20011101

• Antiviral activity and mode of action studies of ribavirin and mycophenolic acid against orthopoxviruses in vitro.

  Antiviral chemistry & chemotherapy 20011101

• Regioselective 2'-silylation of purine ribonucleosides for phosphoramidite RNA synthesis.

  Current protocols in nucleic acid chemistry 20011101

• Short-term 'preconditioning' with inhaled nitric oxide protects rabbit lungs against ischemia-reperfusion injury.

  Transplantation 20011027

• Mechanism of suppression of cytochrome P-450 1A1 expression by tumor necrosis factor-alpha and lipopolysaccharide.

  The Journal of biological chemistry 20011026

• Human phosphatidylethanolamine-binding protein facilitates heterotrimeric G protein-dependent signaling.

  The Journal of biological chemistry 20011026

• Crystal structure of an RNA duplex r(gugucgcac)(2) with uridine bulges.

  Journal of molecular biology 20011026

• Cdc42-independent activation and translocation of the cytostatic p21-activated protein kinase gamma-PAK by sphingosine.

  FEBS letters 20011026

• DNA excited-state dynamics: ultrafast internal conversion and vibrational cooling in a series of nucleosides.

  Journal of the American Chemical Society 20011024

• 2.4 A crystal structure of an oxaliplatin 1,2-d(GpG) intrastrand cross-link in a DNA dodecamer duplex.

  Inorganic chemistry 20011022

• Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus.

  The Journal of biological chemistry 20011019

• Agonist-independent and -dependent oligomerization of dopamine D(2) receptors by fusion to fluorescent proteins.

  FEBS letters 20011019

• Characterization of the functional heterologous desensitization of hypothalamic 5-HT(1A) receptors after 5-HT(2A) receptor activation.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20011015

• The neuronal form of adaptor protein-3 is required for synaptic vesicle formation from endosomes.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20011015

• Coincident spiking activity induces long-term changes in inhibition of neocortical pyramidal cells.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20011015

• Rho1p and Cdc42p act after Ypt7p to regulate vacuole docking.

  The EMBO journal 20011015

• Cdc42p functions at the docking stage of yeast vacuole membrane fusion.

  The EMBO journal 20011015

• Attenuation of G protein-mediated inhibition of N-type calcium currents by expression of caveolins in mammalian NG108-15 cells.

  The Journal of physiology 20011015

• Transient renal effects of sildenafil in male kidney transplant recipients.

  Transplantation 20011015

• Constitutive activation of the mu opioid receptor by mutation of D3.49(164), but not D3.32(147): D3.49(164) is critical for stabilization of the inactive form of the receptor and for its expression.

  Biochemistry 20011009

• Calcium-G protein interactions in the regulation of macrophage secretion.

  The Journal of biological chemistry 20011005

• Efficacy of antipsychotic agents at human 5-HT(1A) receptors determined by [3H]WAY100,635 binding affinity ratios: relationship to efficacy for G-protein activation.

  European journal of pharmacology 20011005

• 'Fleximers'. Design and synthesis of two novel split nucleosides.

  Organic letters 20011004

• Genetic and evolutionary analysis of mutations in the gusA gene that cause the absence of beta-glucuronidase activity in Escherichia coli O157:H7.

  The Journal of infectious diseases 20011001

• Comparative genomics and evolution of genes encoding bacterial (p)ppGpp synthetases/hydrolases (the Rel, RelA and SpoT proteins).

  Journal of molecular microbiology and biotechnology 20011001

• cGMP-mediated inhibition of cardiac L-type Ca(2+) current by a monoclonal antibody against the M(2) ACh receptor.

  American journal of physiology. Cell physiology 20011001

• Pronociceptive effects of nociceptin/orphanin FQ (13-17) at peripheral and spinal level in mice.

  The Journal of pharmacology and experimental therapeutics 20011001

• Reciprocal modulation of alpha(2A)-adrenoceptor and G(alpha o) protein states as determined by carboxy-terminal mutagenesis of a G(alpha o) protein.

  Molecular pharmacology 20011001

• Mechanical stimulation activates Galphaq signaling pathways and 5-hydroxytryptamine release from human carcinoid BON cells.

  The Journal of clinical investigation 20011001

• Enhanced proteolysis of IkappaBalpha and IkappaBbeta proteins in astrocytes by Moloney murine leukemia virus (MoMuLV)-ts1 infection: a potential mechanism of NF-kappaB activation.

  Journal of neurovirology 20011001

• A calorimetric study of 3d metal ions-acyclovir interactions. The 2-hydroxyethoxymethyl group of acyclovir mimics the role of ribose in deoxy-guanosine and guanosine promoting the coordination through N(7).

  Journal of inorganic biochemistry 20011001

• Guanosine 3': 5'-cyclic monophosphate-dependent pathway alterations in ventricular cardiomyocytes of spontaneously hypertensive rats.

  British journal of pharmacology 20011001

• Association of ARF and Rabs with complement receptor type-1 storage vesicles in human neutrophils.

  Journal of leukocyte biology 20011001

• Evaluation of functional GABA(B) receptors in dental pulp.

  Journal of endodontics 20011001

• Ras inhibitors and radiation therapy.

  Seminars in radiation oncology 20011001

• Hamao Umezawa Memorial Award Lecture: 'An Odyssey in the Viral Chemotherapy Field'.

  International journal of antimicrobial agents 20011001

• Cytoskeleton-interacting activity of geiparvarin, diethylstilbestrol and conjugates.

  Chemico-biological interactions 20010928

• The structure of helix III in Xenopus oocyte 5 S rRNA: an RNA stem containing a two-nucleotide bulge.

  Journal of molecular biology 20010928

• Characterization of opiates, neuroleptics, and synthetic analogs at ORL1 and opioid receptors.

  European journal of pharmacology 20010928

• Coordinated agonist regulation of receptor and G protein palmitoylation and functional rescue of palmitoylation-deficient mutants of the G protein G11alpha following fusion to the alpha1b-adrenoreceptor: palmitoylation of G11alpha is not required for interaction with beta*gamma complex.

  The Journal of biological chemistry 20010921

• Up-regulation of spinal mu-opioid receptor function to activate G-protein by chronic naloxone treatment.

  Brain research 20010921

• Design, fabrication, and properties of macroscale supramolecular fibers consisted of fully hydrogen-bonded pseudo-polymer chains.

  Chemical communications (Cambridge, England) 20010921

• Long-range cooperativity due to C5-propynylation of oligopyrimidines enhances specific recognition by uridine of ribo-adenosine over ribo-guanosine.

  Journal of the American Chemical Society 20010919

• Differential signalling of both wild-type and Thr(343)Arg dopamine D(2short) receptor by partial agonists in a G-protein-dependent manner.

  Biochemical pharmacology 20010915

• Single nucleotide polymorphisms in the human mu opioid receptor gene alter basal G protein coupling and calmodulin binding.

  The Journal of biological chemistry 20010914

• Activation of myosin light chain phosphatase in intact arterial smooth muscle during nitric oxide-induced relaxation.

  The Journal of biological chemistry 20010914

• Thrombin-induced activation of RhoA in platelet shape change.

  Biochemical and biophysical research communications 20010914

• Essential requirement of cytosolic phospholipase A(2) for stimulation of NADPH oxidase-associated diaphorase activity in granulocyte-like cells.

  The Journal of biological chemistry 20010907

• Partial agonistic action of endomorphins in the mouse spinal cord.

  Neuroscience letters 20010907

• Type A allatostatins from Drosophila melanogaster and Diplotera puncata activate two Drosophila allatostatin receptors, DAR-1 and DAR-2, expressed in CHO cells.

  Biochemical and biophysical research communications 20010907

• Effect of orally administered guanosine on seizures and death induced by glutamatergic agents.

  Brain research 20010907

• The pH-dependent role of superoxide in riboflavin-catalyzed photooxidation of 8-oxo-7,8-dihydroguanosine.

  Organic letters 20010906

• Stabilities and isomeric equilibria in solutions of monomeric metal-ion complexes of guanosine 5'-triphosphate (GTP4-) and inosine 5'-triphosphate (ITP4-) in comparison with those of adenosine 5'-triphosphate (ATP4-).

  Chemistry (Weinheim an der Bergstrasse, Germany) 20010903

• Changes in cannabinoid CB(1) receptors in striatal and cortical regions of rats with experimental allergic encephalomyelitis, an animal model of multiple sclerosis.

  Synapse (New York, N.Y.) 20010901

• Ca(v)3.2 channel is a molecular substrate for inhibition of T-type calcium currents in rat sensory neurons by nitrous oxide.

  Molecular pharmacology 20010901

• Agonist-, antagonist-, and inverse agonist-regulated trafficking of the delta-opioid receptor correlates with, but does not require, G protein activation.

  The Journal of pharmacology and experimental therapeutics 20010901

• GR89,696: a potent kappa-opioid agonist with subtype selectivity in rhesus monkeys.

  The Journal of pharmacology and experimental therapeutics 20010901

• Ovarian sex steroid-dependent plasticity of nociceptin/orphanin FQ and opioid modulation of spinal dynorphin release.

  The Journal of pharmacology and experimental therapeutics 20010901

• Independent and synergistic interaction of retinal G-protein subunits with bovine rhodopsin measured by surface plasmon resonance.

  The Biochemical journal 20010901

• ATP is required at an early step in compensatory endocytosis in synaptic terminals.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010901

• Inverse agonist properties of antipsychotic agents at cloned, human (h) serotonin (5-HT)(1B) and h5-HT(1D) receptors.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010901

• Real-time analysis of dopamine: antagonist interactions at recombinant human D2long receptor upon modulation of its activation state.

  British journal of pharmacology 20010901

• CXCR4 undergoes complex lineage and inducing agent-dependent dissociation of expression and functional responsiveness to SDF-1alpha during myeloid differentiation.

  Journal of leukocyte biology 20010901

• Expression of CPI-17 and myosin phosphatase correlates with Ca(2+) sensitivity of protein kinase C-induced contraction in rabbit smooth muscle.

  The Journal of physiology 20010901

• The experimental use of antisense oligonucleotides: a guide for the perplexed.

  The Journal of clinical investigation 20010901

• The chemokine interleukin-8 acutely reduces Ca(2+) currents in identified cholinergic septal neurons expressing CXCR1 and CXCR2 receptor mRNAs.

  Journal of neurochemistry 20010901

• Stimulated D(1) dopamine receptors couple to multiple Galpha proteins in different brain regions.

  Journal of neurochemistry 20010901

• Formation of spiroiminodihydantoin nucleoside by reaction of 8-oxo-7,8-dihydro-2'-deoxyguanosine with hypochlorous acid or a myeloperoxidase-H(2)O(2)-Cl(-) system.

  Chemical research in toxicology 20010901

• Profiles of purine and pyrimidine nucleotides in fresh and manufactured tea leaves.

  Journal of agricultural and food chemistry 20010901

• Homologous and heterologous uncoupling of muscarinic M(3) and alpha(1B) adrenoceptors to Galpha(q/11) in SH-SY5Y human neuroblastoma cells.

  British journal of pharmacology 20010901

• Concentrations of nucleotides, nucleosides, purine bases, oxypurines, uric acid, and neuron-specific enolase in the cerebrospinal fluid of children with sepsis.

  Journal of child neurology 20010901

• Regulation of agonist binding to rat ET(B) receptors by cations and GTPgammaS.

  Biochemical pharmacology 20010901

• Evaluation of the tetracycline- and ecdysone-inducible systems for expression of neurotransmitter receptors in mammalian cells.

  The European journal of neuroscience 20010901

• Modulation of N-type Ca2+ channel current kinetics by PMA in rat sympathetic neurons.

  Pflugers Archiv : European journal of physiology 20010901

• Rat pancreatic acinar cells express a cytosolic phospholipase D1b isoform that is not regulated by cholecystokinin.

  Pflugers Archiv : European journal of physiology 20010901

• [A novel gene mutation in a congenital protein S deficiency pedigree].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20010901

• Adenosine A(1) receptor agonism in the immature rat brain and heart.

  European journal of pharmacology 20010831

• Binding, pharmacological and immunological profiles of the delta-selective opioid receptor antagonist HS 378.

  Life sciences 20010831

• 5'-O-alkyl ethers of N,2-substituted adenosine derivatives: partial agonists for the adenosine A1 and A3 receptors.

  Journal of medicinal chemistry 20010830

• Mechanism of NADPH oxidase activation by the Rac/Rho-GDI complex.

  Biochemistry 20010828

• GRAB: a physiologic guanine nucleotide exchange factor for Rab3A, which interacts with inositol hexakisphosphate kinase.

  Neuron 20010816

• Inhibition by guanosine cyclic monophosphate (cGMP) analogues of uptake of [(3)H]3',5'-cGMP without stimulation of ATPase activity in human erythrocyte inside-out vesicles.

  Biochemical pharmacology 20010815

• mu Opioid receptor-mediated G-protein activation by heroin metabolites: evidence for greater efficacy of 6-monoacetylmorphine compared with morphine.

  Biochemical pharmacology 20010815

• Relaxant effect of C-type natriuretic peptide involves endothelium and nitric oxide-cGMP system in rat coronary microvasculature.

  Cardiovascular research 20010815

• Rapid irreversible G protein alpha subunit misfolding due to intramolecular kinetic bottleneck that precedes Mg2+ 'lock' after GTP/GDP exchange.

  Biochemistry 20010814

• Lidocaine potentiates atrial natriuretic peptide-induced relaxation of bovine tracheal smooth muscle.

  European journal of pharmacology 20010810

• Molecular cloning of natriuretic peptide receptor A from bullfrog (Rana catesbeiana) brain and its functional expression.

  Gene 20010808

• Human B cell-attracting chemokine 1 (BCA-1; CXCL13) is an agonist for the human CXCR3 receptor.

  Cytokine 20010807

• Agonist regulation of D(2) dopamine receptor/G protein interaction. Evidence for agonist selection of G protein subtype.

  The Journal of biological chemistry 20010803

• Identification of potential mechanisms for regulation of p115 RhoGEF through analysis of endogenous and mutant forms of the exchange factor.

  The Journal of biological chemistry 20010803

• RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor Activity.

  The Journal of biological chemistry 20010803

• Differential binding of arfaptin 2/POR1 to ADP-ribosylation factors and Rac1.

  Biochemical and biophysical research communications 20010803

• Reduced store-operated Ca(2+) currents in rat basophilic leukaemia cells cultured under serum-free conditions.

  Cell calcium 20010801

• Inhibition of TASK-1 potassium channel by phospholipase C.

  American journal of physiology. Cell physiology 20010801

• Induction of Tmolt4 leukemia cell death by 3,3-disubstituted-6,6-pentamethylene-1,5-diazabicyclo[3.1.0]hexane-2-4-diones: specificity for type II inosine 5'-monophasphate dehydrogenase.

  The Journal of pharmacology and experimental therapeutics 20010801

• Monovalent anions differentially modulate coupling of the beta2-adrenoceptor to G(s)alpha splice variants.

  The Journal of pharmacology and experimental therapeutics 20010801

• G protein-coupled receptor kinases 3 and 6 use different pathways to desensitize the endogenous M3 muscarinic acetylcholine receptor in human SH-SY5Y cells.

  Molecular pharmacology 20010801

• The effects of benzodiazepines on human opioid receptor binding and function.

  Anesthesia and analgesia 20010801

• Oxidative damage is the earliest event in Alzheimer disease.

  Journal of neuropathology and experimental neurology 20010801

• Both serotonin and a nitric-oxide donor cause chloride secretion in rat colonocytes by stimulating cGMP.

  Surgery 20010801

• Distribution and modulation of histamine H(3) receptors in basal ganglia and frontal cortex of healthy controls and patients with Parkinson's disease.

  Neurobiology of disease 20010801

• Impaired inhibitory G-protein function contributes to increased calcium currents in rats with diabetic neuropathy.

  Journal of neurophysiology 20010801

• Characterization of tissue transglutaminase in human osteoblast-like cells.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010801

• A spontaneous nitric oxide donor ameliorates small bowel ischemia-reperfusion injury in dogs.

  Digestive diseases and sciences 20010801

• Hypochlorite-induced damage to nucleosides: formation of chloramines and nitrogen-centered radicals.

  Chemical research in toxicology 20010801

• Regulation of Paramecium primaurelia glycosylphosphatidyl-inositol biosynthesis via dolichol phosphate mannose synthesis.

  Biochimie 20010801

• A new method for the synthesis of N2-alkylguanosines using Mitsunobu reaction as a key step.

  Nucleosides, nucleotides & nucleic acids 20010801

• Physiological and pharmacological characteristics of quisqualic acid-induced K(+)-current response in the ganglion cells of Aplysia.

  The Japanese journal of physiology 20010801

• The mRNA cap structure stimulates rate of poly(A) removal and amplifies processivity of degradation.

  The Journal of biological chemistry 20010727

• Lack of the involvement of mu1-opioid receptor subtype on motivational effects induced by the endogenous mu-opioid receptor ligands endomorphin-1 and -2 in the mouse.

  Neuroscience letters 20010727

• Effects of phospholipase A(2) activating peptides upon GTP-binding protein-evoked adrenocorticotrophin secretion.

  European journal of pharmacology 20010727

• Inhibition of acetylcholine-activated K(+) current by chelerythrine and bisindolylmaleimide I in atrial myocytes from mice.

  European journal of pharmacology 20010727

• Basal tonic release of nitric oxide coupled to cGMP production regulates the vascular reactivity of the mesenteric bed.

  European journal of pharmacology 20010727

• Introduction of alkynyl chains on C-8 of adenosine led to very selective antagonists of the A(3) adenosine receptor.

  Bioorganic & medicinal chemistry letters 20010723

• Plasma membrane estrogen receptors are coupled to endothelial nitric-oxide synthase through Galpha(i).

  The Journal of biological chemistry 20010720

• The dopamine D3 receptor partial agonist, BP 897, is an antagonist at human dopamine D3 receptors and at rat somatodendritic dopamine D3 receptors.

  European journal of pharmacology 20010720

• Chronic cocaine administration decreases the functional coupling of GABA(B) receptors in the rat ventral tegmental area as measured by baclofen-stimulated 35S-GTPgammaS binding.

  Life sciences 20010720

• Ultrafast electron-transfer reactions between thionine and guanosine bases.

  Journal of the American Chemical Society 20010718

• Beta gamma-mediated enhancement of corticotropin-releasing hormone-stimulated adenylyl cyclase activity by activation of gamma-aminobutyric acid(B) receptors in membranes of rat frontal cortex.

  Biochemical pharmacology 20010715

• Guanosine-induced increase in free cytosolic calcium concentration in mouse astrocytes in primary cultures: does it act on an A3 adenosine receptor?

  Journal of neuroscience research 20010715

• A high-performance liquid chromatography radio method for determination of L-ascorbic acid and guanosine 5'-diphosphate-l-galactose, key metabolites of the plant vitamin C pathway.

  Analytical biochemistry 20010715

• Homochiral G-quadruplexes with Ba2+ but not with K+: the cation programs enantiomeric self-recognition.

  Journal of the American Chemical Society 20010711

• Necdin acts as a transcriptional repressor that interacts with multiple guanosine clusters.

  Gene 20010711

• Structure of an RNA hairpin from HRV-14.

  Biochemistry 20010710

• Misacylation and editing by Escherichia coli valyl-tRNA synthetase: evidence for two tRNA binding sites.

  Biochemistry 20010710

• Mechanisms of cold-induced platelet actin assembly.

  The Journal of biological chemistry 20010706

• Furanochromone radical cations: generation, characterization and interaction with DNA.

  Biophysical chemistry 20010702

• Is 'frank' DNA-strand breakage via the guanine radical thermodynamically and sterically possible?

  Chemistry (Weinheim an der Bergstrasse, Germany) 20010702

• Implications of selective type II IMP dehydrogenase (IMPDH) inhibition by the 6-ethoxycarbonyl-3,3-disubstituted-1,5-diazabicyclo[3.1.0]hexane-2,4-diones on tumor cell death.

  Biochemical pharmacology 20010701

• Involvement of astrocytes in purine-mediated reparative processes in the brain.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20010701

• Regulation of I(Cl,swell) in neuroblastoma cells by G protein signaling pathways.

  American journal of physiology. Cell physiology 20010701

• Regulation by GDI of RhoA/Rho-kinase-induced Ca2+ sensitization of smooth muscle myosin II.

  American journal of physiology. Cell physiology 20010701

• Stimulation of guanosine-5'-o-(3-[35S]thio)triphosphate binding in digitonin-permeabilized C6 rat glioma cells: evidence for an organized association of mu-opioid receptors and G protein.

  The Journal of pharmacology and experimental therapeutics 20010701

• Chronic exposure to mu-opioid agonists produces constitutive activation of mu-opioid receptors in direct proportion to the efficacy of the agonist used for pretreatment.

  Molecular pharmacology 20010701

• Evidence for a new G protein-coupled cannabinoid receptor in mouse brain.

  Molecular pharmacology 20010701

• Activation of angiotensin II subtype 2 receptor induces catecholamine release in an extracellular Ca(2+)-dependent manner through a decrease of cyclic guanosine 3',5'-monophosphate production in cultured porcine adrenal medullary chromaffin Cells.

  Endocrinology 20010701

• Cloning and characterization of the cyclic guanosine monophosphate-inhibited phosphodiesterase PDE3A expressed in mouse oocyte.

  Biology of reproduction 20010701

• Relaxation to authentic nitric oxide and SIN-1 in rat isolated mesenteric arteries: variable role for smooth muscle hyperpolarization.

  British journal of pharmacology 20010701

• Association of phosphatidylinositol 3-kinase composed of p110beta-catalytic and p85-regulatory subunits with the small GTPase Rab5.

  Journal of biochemistry 20010701

• Hydroxyfasudil, an active metabolite of fasudil hydrochloride, relaxes the rabbit basilar artery by disinhibition of myosin light chain phosphatase.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20010701

• Characterization of hydantoin products from one-electron oxidation of 8-oxo-7,8-dihydroguanosine in a nucleoside model.

  Chemical research in toxicology 20010701

• SB-272183, a selective 5-HT(1A), 5-HT(1B) and 5-HT(1D) receptor antagonist in native tissue.

  British journal of pharmacology 20010701

• Molecular cloning, pharmacological properties and tissue distribution of the porcine 5-HT(1B) receptor.

  British journal of pharmacology 20010701

• The olfactory G protein G(alphaolf) possesses a lower GDP-affinity and deactivates more rapidly than G(salphashort): consequences for receptor-coupling and adenylyl cyclase activation.

  Journal of neurochemistry 20010701

• Separation of inosine, hypoxanthine, and guanosine by high-performance liquid chromatography on silica.

  Journal of chromatographic science 20010701

• Cytokine-mediated induction of the human elafin gene in pulmonary epithelial cells is regulated by nuclear factor-kappaB.

  American journal of respiratory cell and molecular biology 20010701

• Reaction monitoring of platinum(II) complex--5'-guanosine monophosphate adduct formation by ion exchange liquid chromatography/electrospray ionization mass spectrometry.

  Journal of mass spectrometry : JMS 20010701

• Bridging the NFAT and NF-kappaB families: NFAT5 dimerization regulates cytokine gene transcription in response to osmotic stress.

  Immunity 20010701

• Mechanically induced potentials in rat atrial fibroblasts depend on actin and tubulin polymerisation.

  Pflugers Archiv : European journal of physiology 20010701

• Modulation of ion channels in rat neurons by the constituents of Hypericum perforatum.

  Pharmacopsychiatry 20010701

• RNase-stable RNA: conformational parameters of the nucleic acid backbone for binding to RNase T1.

  Biological chemistry 20010701

• SoRI 9409, a non-peptide opioid mu receptor agonist/delta receptor antagonist, fails to stimulate [35S]-GTP-gamma-S binding at cloned opioid receptors.

  Brain research bulletin 20010701

• Substance P and neurokinin A mediate sensory synaptic transmission in young rat dorsal horn neurons.

  Brain research bulletin 20010701

• Polymorphism in codon 17 of the CTLA-4 gene (+49 A/G) is not associated with susceptibility to rheumatoid arthritis in British Caucasians.

  Tissue antigens 20010701

• Intracellular phosphorylation of carbocyclic 3-deazaadenosine, an anti-Ebola virus agent.

  Antiviral chemistry & chemotherapy 20010701

• The function of interdomain interactions in controlling nucleotide exchange rates in transducin.

  The Journal of biological chemistry 20010629

• Palmitoylation of CCR5 is critical for receptor trafficking and efficient activation of intracellular signaling pathways.

  The Journal of biological chemistry 20010629

• Characterization of a G protein-activated phosphoinositide 3-kinase in vascular smooth muscle cell nuclei.

  The Journal of biological chemistry 20010622

• Conserved base-pairings between C266-A268 and U307-G309 in the P7 of the Tetrahymena ribozyme is nonessential for the in vitro self-splicing reaction.

  Biochemical and biophysical research communications 20010622

• Agonist-stimulated [35S]GTPgammaS autoradiography: optimization for high sensitivity.

  European journal of pharmacology 20010622

• T-1032, a novel specific phosphodiesterase type 5 inhibitor, increases venous compliance in anesthetized rats.

  European journal of pharmacology 20010622

• Slow motion in the CAA*TTG sequence of a DNA decamer duplex studied by NMR.

  Biochemistry 20010619

• The cyclohexene ring as bioisostere of a furanose ring: synthesis and antiviral activity of cyclohexenyl nucleosides.

  Bioorganic & medicinal chemistry letters 20010618

• Opioid peptide receptor studies. 15. Relative efficacy of 4-[(N-allyl-3-methyl-4-piperidinyl)phenylamino]-N,N-diethylbenzamide and related compounds at the cloned human delta-opioid receptor.

  Synapse (New York, N.Y.) 20010615

• Light- and guanosine 5'-3-O-(thio)triphosphate-sensitive localization of a G protein and its effector on detergent-resistant membrane rafts in rod photoreceptor outer segments.

  The Journal of biological chemistry 20010615

• Novel G protein-coupled responses in leukocytes elicited by a chemotactic bacteriophage displaying a cell type-selective binding peptide.

  Journal of immunology (Baltimore, Md. : 1950) 20010615

• Influence of degradation on binding properties and biological activity of endomorphin 1.

  Biochemical and biophysical research communications 20010615

• The McrBC restriction endonuclease assembles into a ring structure in the presence of G nucleotides.

  The EMBO journal 20010615

• Thiophosphorylation-induced Ca(2+) sensitization of guinea-pig ileum contractility is not mediated by Rho-associated kinase.

  The Journal of physiology 20010615

• In vitro inhibitory effects of J-113397 on nociceptin/orphanin FQ-stimulated.

  Neuroreport 20010613

• Biochemical analysis of yeast G(alpha) mutants that enhance adaptation to pheromone.

  Biochemical and biophysical research communications 20010608

• Distinct characteristic of Galpha(h) (transglutaminase II) by compartment: GTPase and transglutaminase activities.

  Biochemical and biophysical research communications 20010608

• Casein kinase I associates with members of the centaurin-alpha family of phosphatidylinositol 3,4,5-trisphosphate-binding proteins.

  The Journal of biological chemistry 20010601

• Evidence of involvement of GIRK1/GIRK4 in long-term desensitization of cardiac muscarinic K+ channels.

  American journal of physiology. Heart and circulatory physiology 20010601

• Involvement of spinal protein kinase Cgamma in the attenuation of opioid mu-receptor-mediated G-protein activation after chronic intrathecal administration of [D-Ala2,N-MePhe4,Gly-Ol(5)]enkephalin.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010601

• Antiparkinsonian agent piribedil displays antagonist properties at native, rat, and cloned, human alpha(2)-adrenoceptors: cellular and functional characterization.

  The Journal of pharmacology and experimental therapeutics 20010601

• Functional differences between full and partial agonists: evidence for ligand-specific receptor conformations.

  The Journal of pharmacology and experimental therapeutics 20010601

• Novel properties of the nucleolar targeting signal of human angiogenin.

  Biochemical and biophysical research communications 20010601

• Monoclonal antibody to single-stranded DNA: a potential tool for DNA repair studies.

  Biochemical and biophysical research communications 20010601

• Inhibition of calcium channels by opioid- and adenosine-receptor agonists in neurons of the nucleus accumbens.

  British journal of pharmacology 20010601

• [125I]-S36057: a new and highly potent radioligand for the melanin-concentrating hormone receptor.

  British journal of pharmacology 20010601

• LeuO expression in response to starvation for branched-chain amino acids.

  The Journal of biological chemistry 20010601

• Group I mGluRs coupled to G proteins are regulated by tyrosine kinase in dopamine neurons of the rat midbrain.

  Journal of neurophysiology 20010601

• Endocytosis in identified rat corticotrophs.

  The Journal of physiology 20010601

• Involvement of cyclic guanosine 3',5'-monophosphate in nitric oxide-induced glucagon secretion from pancreatic alpha cells.

  Metabolism: clinical and experimental 20010601

• Elucidation of the initial step of oligonucleotide fragmentation in matrix-assisted laser desorption/ionization using modified nucleic acids.

  Journal of the American Society for Mass Spectrometry 20010601

• Modulation of the hyperpolarisation-activated current, Ih, in rat facial motoneurones in vitro by ZD-7288.

  Neuropharmacology 20010601

• Neurotensin excitation of serotonergic neurons in the rat nucleus raphe magnus: ionic and molecular mechanisms.

  Neuropharmacology 20010601

• Role of the angiotensin AT2 receptor in blood pressure regulation and therapeutic implications.

  American journal of hypertension 20010601

• Dual coupling of opioid receptor-like (ORL1) receptors to adenylyl cyclase in the different layers of the rat main olfactory bulb.

  Journal of neurochemistry 20010601

• Inverse agonists and neutral antagonists at mu opioid receptor (MOR): possible role of basal receptor signaling in narcotic dependence.

  Journal of neurochemistry 20010601

• Imaging of single hairpin ribozymes in solution by atomic force microscopy.

  RNA (New York, N.Y.) 20010601

• Poly(A) polymerase from Escherichia coli adenylylates the 3'-hydroxyl residue of nucleosides, nucleoside 5'-phosphates and nucleoside(5')oligophospho(5')nucleosides (NpnN).

  European journal of biochemistry 20010601

• Rett syndrome from quintuple and triple deletions within the MECP2 deletion hotspot region.

  Clinical genetics 20010601

• GTP gamma S-induced Ca2+ activated Cl- currents: its stable induction by Gq alpha overexpression in Xenopus oocytes.

  Japanese journal of pharmacology 20010601

• Inosine monophosphate dehydrogenase (IMPDH) inhibition in vitro suppresses lymphocyte proliferation and the production of immunoglobulins, autoantibodies and cytokines in splenocytes from MRLlpr/lpr mice.

  Clinical and experimental immunology 20010601

• HIV-1 LTR C/EBP binding site sequence configurations preferentially encountered in brain lead to enhanced C/EBP factor binding and increased LTR-specific activity.

  Journal of neurovirology 20010601

• The role of nitric oxide in amyotrophic lateral sclerosis.

  Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20010601

• Enhanced regional AT(2)-receptor and PKC(epsilon) expression during cardioprotection induced by AT(1)-receptor blockade after reperfused myocardial infarction.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20010601

• [The contents and their change of nucleosides from natural Cordyceps sinensis and cultured cordyceps mycelia].

  Yao xue xue bao = Acta pharmaceutica Sinica 20010601

• Toxoplasma gondii ADP-ribosylation factor 1 mediates enhanced release of constitutively secreted dense granule proteins.

  The Journal of biological chemistry 20010525

• Characterization of the nuclear import pathway for HIV-1 integrase.

  The Journal of biological chemistry 20010525

• Pseudoginsenoside-F11 attenuates morphine-induced signalling in Chinese hamster ovary-mu cells.

  Neuroreport 20010525

• 5-HT1A receptor activation and antidepressant-like effects: F 13714 has high efficacy and marked antidepressant potential.

  European journal of pharmacology 20010525

• Identification of a truncated form of the G-protein regulator AGS3 in heart that lacks the tetratricopeptide repeat domains.

  The Journal of biological chemistry 20010518

• A GDP/GTP exchange factor involved in linking a spatial landmark to cell polarity.

  Science (New York, N.Y.) 20010518

• Role of Rab9 GTPase in facilitating receptor recruitment by TIP47.

  Science (New York, N.Y.) 20010518

• Lack of effects by sigma ligands on neuropeptide Y-induced G-protein activation in rat hippocampus and cerebellum.

  Brain research 20010518

• Liquid-core waveguide technology for coupling column liquid chromatography and Raman spectroscopy.

  Journal of chromatography. A 20010518

• Phosphatidylinositol transfer proteins and protein kinase C make separate but non-interacting contributions to the phosphorylation state necessary for secretory competence in rat mast cells.

  The Biochemical journal 20010515

• Cannabinoid receptor agonist-stimulated [35S]guanosine triphosphate gammaS binding in the brain of C57BL/6 and DBA/2 mice.

  Journal of neuroscience research 20010515

• Recognition and kinetics for excision of a base lesion within clustered DNA damage by the Escherichia coli proteins Fpg and Nth.

  Biochemistry 20010515

• Transcriptional regulation of CD28 expression by CD28GR, a novel promoter element located in exon 1 of the CD28 gene.

  Journal of immunology (Baltimore, Md. : 1950) 20010515

• Studies on inhibition of human platelet function by sodium nitroprusside. Kinetic evaluation of the effect on aggregation and cyclic nucleotide content.

  Thrombosis research 20010515

• Oxidative damage and stress response from ochratoxin a exposure in rats.

  Free radical biology & medicine 20010515

• Functional and anatomical localization of mu opioid receptors in the striatum, amygdala, and extended amygdala of the nonhuman primate.

  The Journal of comparative neurology 20010514

• A comprehensive characterization of a group IB intron and its encoded maturase reveals that protein-assisted splicing requires an almost intact intron RNA.

  Journal of molecular biology 20010511

• Long-range cooperativity in molecular recognition of RNA by oligodeoxynucleotides with multiple C5-(1-propynyl) pyrimidines.

  Journal of the American Chemical Society 20010509

• Melatonin acts as antioxidant and pro-oxidant in an organotypic slice culture model of Alzheimer's disease.

  Neuroreport 20010508

• Characterization of nucleoside transport systems in cultured rat epididymal epithelium.

  American journal of physiology. Cell physiology 20010501

• Arachidonic acid both inhibits and enhances whole cell calcium currents in rat sympathetic neurons.

  American journal of physiology. Cell physiology 20010501

• Arachidonic acid reversibly enhances N-type calcium current at an extracellular site.

  American journal of physiology. Cell physiology 20010501

• VX-497: a novel, selective IMPDH inhibitor and immunosuppressive agent.

  Journal of pharmaceutical sciences 20010501

• Nitric oxide decreases lung liquid production via guanosine 3',5'-cyclic monophosphate.

  American journal of physiology. Lung cellular and molecular physiology 20010501

• Modulation of ligand responses by coupling of alpha(2A)-adrenoceptors to diverse G(alpha)-proteins.

  Biochemical pharmacology 20010501

• Comparison of pharmacological activities of buprenorphine and norbuprenorphine: norbuprenorphine is a potent opioid agonist.

  The Journal of pharmacology and experimental therapeutics 20010501

• Ionotropic histamine receptors and H2 receptors modulate supraoptic oxytocin neuronal excitability and dye coupling.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010501

• Mitochondrial abnormalities in Alzheimer's disease.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010501

• Sustained stimulation of exocytosis triggers continuous membrane retrieval in rat pituitary somatotrophs.

  The Journal of physiology 20010501

• Identification of a novel nuclear guanosine triphosphate-binding protein differentially expressed in renal disease.

  Journal of the American Society of Nephrology : JASN 20010501

• Defining the catalytic metal ion interactions in the Tetrahymena ribozyme reaction.

  Biochemistry 20010501

• Bacteriophage T7 RNA polymerase transcription elongation is inhibited by site-specific, stereospecific benzo[c]phenanthrene diol epoxide DNA lesions.

  Biochemistry 20010501

• Inhibition of GDP/GTP exchange on G alpha subunits by proteins containing G-protein regulatory motifs.

  Biochemistry 20010501

• The elevated GC content at exonic third sites is not evidence against neutralist models of isochore evolution.

  Molecular biology and evolution 20010501

• Pseudogenes, junk DNA, and the dynamics of Rickettsia genomes.

  Molecular biology and evolution 20010501

• Evolution of endogenous retrovirus-like elements of the woolly mammoth (Mammuthus primigenius) and its relatives.

  Molecular biology and evolution 20010501

• Induction of mutant lymphocytes in cyclophosphamide- and chlorambucil-treated patients.

  Mutagenesis 20010501

• In vivo control of soluble guanylate cyclase activation by nitric oxide: a kinetic analysis.

  Biophysical journal 20010501

• Functional characterization of a human receptor for neuropeptide FF and related peptides.

  British journal of pharmacology 20010501

• Respective contributions of alpha-adrenergic and non-adrenergic mechanisms in the hypotensive effect of imidazoline-like drugs.

  British journal of pharmacology 20010501

• Agonist efficacy and receptor efficiency in heterozygous CB1 knockout mice: relationship of reduced CB1 receptor density to G-protein activation.

  Journal of neurochemistry 20010501

• SKF83959 exhibits biochemical agonism by stimulating [(35)S]GTP gamma S binding and phosphoinositide hydrolysis in rat and monkey brain.

  Neuropharmacology 20010501

• Inhibition of adenylyl cyclase activity in brain membrane fractions by arachidonic acid and related unsaturated fatty acids.

  Archives of biochemistry and biophysics 20010501

• Functional studies of bradykinin receptors in Chinese hamster ovary cells stably expressing the human B2 bradykinin receptor.

  International immunopharmacology 20010501

• Combined phosphodiesterase inhibition and beta-blockade in the GI104313, decreases ischemia-induced arrhythmias in the rat.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20010501

• Estriol improves membrane fluidity of erythrocytes by the nitric oxide-dependent mechanism: an electron paramagnetic resonance study.

  Hypertension research : official journal of the Japanese Society of Hypertension 20010501

• The UDPase activity of the Kluyveromyces lactis Golgi GDPase has a role in uridine nucleotide sugar transport into Golgi vesicles.

  Glycobiology 20010501

• Nitric oxide production during the early neonatal period in small-for-gestational-age infants.

  Acta paediatrica (Oslo, Norway : 1992) 20010501

• gsk disruption leads to guanosine accumulation in Escherichia coli.

  Bioscience, biotechnology, and biochemistry 20010501

• A base-labile protecting group (fluorenylmethoxycarbonyl) for the 5'-hydroxy function of nucleosides.

  Current protocols in nucleic acid chemistry 20010501

• 2'-Hydroxyl-protecting groups that are either photochemically labile or sensitive to fluoride ions.

  Current protocols in nucleic acid chemistry 20010501

• Homo- and heterodimerization of somatostatin receptor subtypes. Inactivation of sst(3) receptor function by heterodimerization with sst(2A).

  The Journal of biological chemistry 20010427

• Adenylate cyclase in prothoracic glands during the last larval instar of the silkworm, Bombyx mori.

  Insect biochemistry and molecular biology 20010427

• Structure-activity relationship studies of melanin-concentrating hormone (MCH)-related peptide ligands at SLC-1, the human MCH receptor.

  The Journal of biological chemistry 20010427

• Novel signalling events mediated by muscarinic receptor subtypes.

  Life sciences 20010427

• Elucidating the role of muscarinic receptors in psychosis.

  Life sciences 20010427

• Effect of N-alkyl and N-alkenyl substituents in noroxymorphindole, 17-substituted-6,7-dehydro-4,5alpha-epoxy-3,14-dihydroxy-6,7:2',3'-indolomorphinans, on opioid receptor affinity, selectivity, and efficacy.

  Journal of medicinal chemistry 20010426

• Hydrogen-bond-mediated photoinduced electron-transfer: novel dimethylaniline-anthracene ensembles formed via Watson-Crick base-pairing.

  Journal of the American Chemical Society 20010425

• Isolation of a novel interleukin-1-inducible nuclear protein bearing ankyrin-repeat motifs.

  The Journal of biological chemistry 20010420

• Rab3a binding and secretion-enhancing domains in Rim1 are separate and unique. Studies in adrenal chromaffin cells.

  The Journal of biological chemistry 20010420

• Genomic organization and characterization of splice variants of the human histamine H3 receptor.

  The Biochemical journal 20010415

• RGS2 blocks slow muscarinic inhibition of N-type Ca(2+) channels reconstituted in a human cell line.

  The Journal of physiology 20010415

• Retrograde transport of transcription factor NF-kappa B in living neurons.

  The Journal of biological chemistry 20010413

• D2 dopamine receptor-G protein coupling. Cross-regulation of agonist and guanosine nucleotide binding sites.

  Neuroscience letters 20010413

• Increased alpha3-fucosylation of alpha(1)-acid glycoprotein in patients with congenital disorder of glycosylation type IA (CDG-Ia).

  FEBS letters 20010413

• Synthesis, characterization, and reactivity of trans-[PtCl(R'R''SO)(A)2]NO3 (R'R''SO = Me2SO, MeBzSO, MePhSO; A= NH3, py, pic). Crystal structure of trans-[PtCl(Me2SO)(py)2]+.

  Inorganic chemistry 20010409

• Mutation W284L of the human delta opioid receptor reveals agonist specific receptor conformations for G protein activation.

  Life sciences 20010406

• Developmental regulation of GABA(B) receptor function in rat spinal cord.

  Life sciences 20010406

• Spiroiminodihydantoin is the major product of the 8-oxo-7,8-dihydroguanosine reaction with peroxynitrite in the presence of thiols and guanosine photooxidation by methylene blue.

  Organic letters 20010405

• G protein coupling to M1 and M3 muscarinic receptors in sublingual glands.

  American journal of physiology. Cell physiology 20010401

• Ca2+-induced contraction of cat esophageal circular smooth muscle cells.

  American journal of physiology. Cell physiology 20010401

• Identification of two prokineticin cDNAs: recombinant proteins potently contract gastrointestinal smooth muscle.

  Molecular pharmacology 20010401

• Human interferon-inducible 10-kDa protein and human interferon-inducible T cell alpha chemoattractant are allotopic ligands for human CXCR3: differential binding to receptor states.

  Molecular pharmacology 20010401

• Activation of guanosine 5'-[gamma-(35)S]thio-triphosphate binding through M(1) muscarinic receptors in transfected Chinese hamster ovary cell membranes; 1. Mathematical analysis of catalytic G protein activation.

  Molecular pharmacology 20010401

• Activation of guanosine 5'-[gamma-(35)S]thio-triphosphate binding through M(1) muscarinic receptors in transfected Chinese Hamster ovary cell membranes: 2. Testing the 'two-states' model of receptor activation.

  Molecular pharmacology 20010401

• Suppression by a sesquiterpene lactone from Carpesium divaricatum of inducible nitric oxide synthase by inhibiting nuclear factor-kappaB activation.

  Biochemical pharmacology 20010401

• Measurement of 8-oxo-2'-deoxyguanosine and 8-oxo-2'-deoxyadenosine in DNA and human urine by high performance liquid chromatography-electrospray tandem mass spectrometry.

  Free radical biology & medicine 20010401

• Probing the mechanism of rhodopsin-catalyzed transducin activation.

  Journal of neurochemistry 20010401

• Effect of nitric oxide on megakaryocyte growth induced by thrombopoietin.

  The Journal of laboratory and clinical medicine 20010401

• Inwardly rectifying K(+) current and differentiation of human placental cytotrophoblast cells in culture.

  Placenta 20010401

• Proapoptotic anti-inflammatory drugs.

  Urology 20010401

• Hyperinsulinism/hyperammonemia syndrome in children with regulatory mutations in the inhibitory guanosine triphosphate-binding domain of glutamate dehydrogenase.

  The Journal of clinical endocrinology and metabolism 20010401

• [(35)S]GTPgammaS autoradiography reveals a wide distribution of G(i/o)-linked ADP receptors in the nervous system: close similarities with the platelet P2Y(ADP) receptor.

  Journal of neurochemistry 20010401

• Analysis of peroxynitrite reactions with guanine, xanthine, and adenine nucleosides by high-pressure liquid chromatography with electrochemical detection: C8-nitration and -oxidation.

  Chemical research in toxicology 20010401

• Novel histamine H(3)-receptor antagonists and partial agonists with a non-aminergic structure.

  British journal of pharmacology 20010401

• Involvement of PKA, PKC, and Ca2+ in LPS-activated expression of the chicken lysozyme gene.

  Journal of leukocyte biology 20010401

• Cell type-specific differences in the coupling of recombinant mGlu1alpha receptors to endogenous G protein sub-populations.

  Neuropharmacology 20010401

• Regulation of phospholipase Cbeta activity by muscarinic acetylcholine and 5-HT(2) receptors in crude and synaptosomal membranes from human cerebral cortex.

  Neuropharmacology 20010401

• Guanylin family: new intestinal peptides regulating electrolyte and water homeostasis.

  Journal of gastroenterology 20010401

• Angiotensin II and serotonin potentiate endothelin-1-induced vascular smooth muscle cell proliferation.

  Journal of hypertension 20010401

• From RNA world to protein: an eagle's eye view of the role of guanosine in tracing the antiquity of the intron.

  Journal of biomolecular structure & dynamics 20010401

• Evidence for higher-order structure formation by the c-myb 18-mer phosphorothioate antisense (codons 2-7) oligodeoxynucleotide: potential relationship to antisense c-myb inhibition.

  Antisense & nucleic acid drug development 20010401

• Synthesis, pharmacological characterization and QSAR studies on 2-substituted indole melatonin receptor ligands.

  Bioorganic & medicinal chemistry 20010401

• GTP cyclohydrolase I feedback regulatory protein-dependent and -independent inhibitors of GTP cyclohydrolase I.

  Archives of biochemistry and biophysics 20010401

• ATP inhibits insulin-degrading enzyme activity.

  Experimental biology and medicine (Maywood, N.J.) 20010401

• Gi2 proteins couple somatostatin receptors to low-conductance K+ channels in rat pancreatic alpha-cells.

  Pflugers Archiv : European journal of physiology 20010401

• Chemorepellent signaling through the PACAP/lysozyme receptor is mediated through cAMP and PKC in Tetrahymena thermophila.

  Journal of comparative physiology. A, Sensory, neural, and behavioral physiology 20010401

• Alteration of dopamine transport in the striatum and nucleus accumbens of ovariectomized and estrogen-primed rats following N-(p-isothiocyanatophenethyl) spiperone (NIPS) treatment.

  Brain research bulletin 20010401

• Cholinergic, noradrenergic, and serotonergic inhibition of fast synaptic transmission in spinal lumbar dorsal horn of rat.

  Brain research bulletin 20010401

• Orphanin FQ/nociceptin binds to functionally coupled ORL1 receptors on human immune cell lines and alters peripheral blood mononuclear cell proliferation.

  Brain research bulletin 20010401

• Reconstitution in lipid bilayer of smooth muscle cation channels activated through a GTP-binding protein.

  Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20010401

• Mechanism-related changes in the gene transcription and protein synthesis patterns of Haemophilus influenzae after treatment with transcriptional and translational inhibitors.

  Proteomics 20010401

• A direct inhibitory role for the Rab3-specific effector, Noc2, in Ca2+-regulated exocytosis in neuroendocrine cells.

  The Journal of biological chemistry 20010330

• Human mismatch repair and G*T mismatch binding by hMutSalpha in vitro is inhibited by adriamycin, actinomycin D, and nogalamycin.

  The Journal of biological chemistry 20010330

• Functional coupling with Galpha(q) and Galpha(i1) protein subunits promotes high-affinity agonist binding to the neurotensin receptor NTS-1 expressed in Escherichia coli.

  FEBS letters 20010330

• Activation of glutamate uptake by guanosine in primary astrocyte cultures.

  Neuroreport 20010326

• Receptor-mediated activation of heterotrimeric G-proteins in living cells.

  Science (New York, N.Y.) 20010323

• Receptor binding and biological activity of the dermorphin analog Tyr-D-Arg(2)-Phe-Sar (TAPS).

  European journal of pharmacology 20010323

• Correlation between processing efficiency for ribonuclease P minimal substrates and conformation of the nucleotide -1 at the cleavage position.

  Biochemistry 20010320

• Evaluating the signal transduction mechanism of the parathyroid hormone 1 receptor. Effect of receptor-G-protein interaction on the ligand binding mechanism and receptor conformation.

  The Journal of biological chemistry 20010316

• Mu opioid receptor efficacy and potency of morphine-6-glucuronide in neonatal guinea pig brainstem membranes: comparison with transfected CHO cells.

  Brain research bulletin 20010315

• Ras catalyzes GTP hydrolysis by shifting negative charges from gamma- to beta-phosphate as revealed by time-resolved FTIR difference spectroscopy.

  Biochemistry 20010313

• Structure of a eukaryotic decoding region A-site RNA.

  Journal of molecular biology 20010309

• Structural origins of aminoglycoside specificity for prokaryotic ribosomes.

  Journal of molecular biology 20010309

• Different domains in the third intracellular loop of the GLP-1 receptor are responsible for Galpha(s) and Galpha(i)/Galpha(o) activation.

  Biochimica et biophysica acta 20010309

• Cytosolic high K(m) 5'-nucleotidase and 5'(3')-deoxyribonucleotidase in substrate cycles involved in nucleotide metabolism.

  The Journal of biological chemistry 20010302

• Radioligand binding properties of VV-hemorphin 7, an atypical opioid peptide.

  Biochemical and biophysical research communications 20010302

• Inhibitory effects of SR141716A on G-protein activation in rat brain.

  European journal of pharmacology 20010302

• Tetraplex formation by the progressive myoclonus epilepsy type-1 repeat: implications for instability in the repeat expansion diseases.

  FEBS letters 20010302

• Selective inactivation of guanine-nucleotide-binding regulatory protein (G-protein) alpha and betagamma subunits by urea.

  The Biochemical journal 20010301

• cAMP-independent phosphorylation activation of CFTR by G proteins in native human sweat duct.

  American journal of physiology. Cell physiology 20010301

• Effects of cellular ATP depletion on glucose transport and insulin signaling in 3T3-L1 adipocytes.

  American journal of physiology. Endocrinology and metabolism 20010301

• Ontogenic and longitudinal activity of Na(+)-nucleoside transporters in the human intestine.

  American journal of physiology. Gastrointestinal and liver physiology 20010301

• Maturation depresses cGMP-mediated decreases in [Ca2+]i and Ca2+ sensitivity in ovine cranial arteries.

  American journal of physiology. Heart and circulatory physiology 20010301

• Na+ reabsorption in cultured rat epididymal epithelium via the Na+/nucleoside cotransporter.

  Biology of reproduction 20010301

• Insertional mutagenesis of the arginine cage domain of the gonadotropin-releasing hormone receptor.

  Molecular endocrinology (Baltimore, Md.) 20010301

• Differential expression of functional guanylyl cyclases in melanocytes: absence of nitric-oxide-sensitive isoform in metastatic cells.

  The Journal of investigative dermatology 20010301

• Effect of mycophenolate mofetil therapy on inosine monophosphate dehydrogenase induction in red blood cells of heart transplant recipients.

  Clinical pharmacology and therapeutics 20010301

• Heparin modulates integrin function in human platelets.

  Journal of vascular surgery 20010301

• Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins.

  Nature 20010301

• Biochemical detection of monovalent metal ion binding sites within RNA.

  Methods (San Diego, Calif.) 20010301

• Characterization of [3H]CGP 12177 binding to beta-adrenergic receptors in intact eel hepatocytes.

  General and comparative endocrinology 20010301

• Characterization of the AT(4) receptor in a human neuroblastoma cell line (SK-N-MC).

  Journal of neurochemistry 20010301

• Active intestinal absorption of nucleosides by Na+-dependent transport across the brush border membrane in cows.

  Journal of dairy science 20010301

• Inhibitory effects of nicorandil on rat mesangial cell proliferation via the protein kinase G pathway.

  Nephron 20010301

• Carboxyl terminal sequence of human phospholipase Cgamma2.

  Platelets 20010301

• Estrogens act in rat hippocampus and frontal cortex to produce rapid, receptor-mediated decreases in serotonin 5-HT(1A) receptor function.

  Neuroendocrinology 20010301

• Transmembrane signaling through phospholipase C in cortical and hippocampal membranes of psychogenetically selected rat lines.

  Psychopharmacology 20010301

• [Quality of erythrocyte concentrates in additive solutions--evaluation with hemorrheological methods].

  Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 20010301

• Comparison of the reactivity of oxaliplatin, pt(diaminocyclohexane)Cl2 and pt(diaminocyclohexane1)(OH2)2(2+) with guanosine and L-methionine.

  Journal of inorganic biochemistry 20010301

• Investigation of various genotype characteristics for inosine accumulation in Escherichia coli W3110.

  Bioscience, biotechnology, and biochemistry 20010301

• The effect of cytidine on the structure and function of an RNA ligase ribozyme.

  RNA (New York, N.Y.) 20010301

• Purification of Drosophila snRNPs and characterization of two populations of functional U1 particles.

  RNA (New York, N.Y.) 20010301

• Biological activities of two porcine growth hormone-releasing hormone receptor isoforms.

  Archives of biochemistry and biophysics 20010301

• Famciclovir treatment of hepatitis B infection following liver transplantation: a long-term, multi-centre study.

  Transplant infectious disease : an official journal of the Transplantation Society 20010301

• New antiretroviral agents.

  The Hopkins HIV report : a bimonthly newsletter for healthcare providers 20010301

• Thermodynamics of RNA internal loops with a guanosine-guanosine pair adjacent to another noncanonical pair.

  Biochemistry 20010227

• HU binding to DNA: evidence for multiple complex formation and DNA bending.

  Biochemistry 20010227

• Protein kinase C phosphorylates RGS2 and modulates its capacity for negative regulation of Galpha 11 signaling.

  The Journal of biological chemistry 20010223

• Nrg-1 belongs to the endothelial differentiation gene family of G protein-coupled sphingosine-1-phosphate receptors.

  The Journal of biological chemistry 20010223

• Phospholipase Cdelta1 is a guanine nucleotide exchanging factor for transglutaminase II (Galpha h) and promotes alpha 1B-adrenoreceptor-mediated GTP binding and intracellular calcium release.

  The Journal of biological chemistry 20010223

• Depletion of phosphatidylinositol 4,5-bisphosphate by activation of phospholipase C-coupled receptors causes slow inhibition but not desensitization of G protein-gated inward rectifier K+ current in atrial myocytes.

  The Journal of biological chemistry 20010223

• RGS2 regulates signal transduction in olfactory neurons by attenuating activation of adenylyl cyclase III.

  Nature 20010222

• Stability and structure of RNA duplexes containing isoguanosine and isocytidine.

  Journal of the American Chemical Society 20010221

• Direct interaction of Rab4 with syntaxin 4.

  The Journal of biological chemistry 20010216

• Isolation of a new melanoma antigen, MART-2, containing a mutated epitope recognized by autologous tumor-infiltrating T lymphocytes.

  Journal of immunology (Baltimore, Md. : 1950) 20010215

• Neuropeptide Y receptors differentially modulate G-protein-activated inwardly rectifying K+ channels and high-voltage-activated Ca2+ channels in rat thalamic neurons.

  The Journal of physiology 20010215

• Synthesis and photodynamic activity of a cationic zinc monoazaporphyrin bearing a nitrogen atom at the peripheral position.

  Bioorganic & medicinal chemistry letters 20010212

• Identification of a conserved motif in the yeast golgi GDP-mannose transporter required for binding to nucleotide sugar.

  The Journal of biological chemistry 20010209

• Effects of wortmannin upon the late stages of the secretory pathway of AtT-20 cells.

  European journal of pharmacology 20010209

• A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling.

  The Journal of biological chemistry 20010202

• Modulation of neuronal nitric oxide release by soluble guanylyl cyclase in guinea pig colon.

  Biochemical and biophysical research communications 20010202

• Sildenafil inhibits gastroduodenal motility.

  Alimentary pharmacology & therapeutics 20010201

• A novel activation of Ca(2+)-activated Cl(-) channel in Xenopus oocytes by Ginseng saponins: evidence for the involvement of phospholipase C and intracellular Ca(2+) mobilization.

  British journal of pharmacology 20010201

• Gallbladder muscle dysfunction in patients with chronic acalculous disease.

  Gastroenterology 20010201

• Biophysical properties, pharmacology, and modulation of human, neuronal L-type (alpha(1D), Ca(V)1.3) voltage-dependent calcium currents.

  Journal of neurophysiology 20010201

• A novel proton-dependent nucleoside transporter, CeCNT3, from Caenorhabditis elegans.

  Molecular pharmacology 20010201

• Characterization of a G protein-coupled receptor for nicotinic acid.

  Molecular pharmacology 20010201

• Effect of different 5-hydroxytryptamine receptor subtype antagonists on the micturition reflex in rats.

  BJU international 20010201

• CB1 receptor-G protein association. Subtype selectivity is determined by distinct intracellular domains.

  European journal of biochemistry 20010201

• Phosphorylation and desensitization of alpha1d-adrenergic receptors.

  The Biochemical journal 20010201

• LPS induction of I kappa B-alpha degradation and iNOS expression in a skin dendritic cell line is prevented by the janus kinase 2 inhibitor, Tyrphostin b42.

  Nitric oxide : biology and chemistry 20010201

• G(q/11) and G(i/o) activation profiles in CHO cells expressing human muscarinic acetylcholine receptors: dependence on agonist as well as receptor-subtype.

  British journal of pharmacology 20010201

• Diurnal rhythmicity in intestinal SGLT-1 function, V(max), and mRNA expression topography.

  American journal of physiology. Gastrointestinal and liver physiology 20010201

• Electron transfer vs. proton transfer within radical-cation clusters of guanosine and deoxyguanosine with substituted naphthalenes and sinapinic acid.

  Journal of the American Society for Mass Spectrometry 20010201

• TRAPP I implicated in the specificity of tethering in ER-to-Golgi transport.

  Molecular cell 20010201

• Methylene blue reduces lung fluid filtration during the early phase of endotoxemia in awake sheep.

  Critical care medicine 20010201

• The anti-herpesvirus activity of (1'S,2'R)-9-[[1',2'-bis(hydroxymethyl)-cycloprop-1'-yl]methyl]guanine is markedly potentiated by the immunosuppressive agent mycophenolate mofetil.

  Antiviral research 20010201

• The stringent response, sigmaH-dependent gene expression and sporulation in Bacillus subtilis.

  Molecular & general genetics : MGG 20010201

• The use of L-arginine [correction of F-arginine] and phosphodiesterase inhibitor (dipyridamole) to wean from inhaled nitric oxide.

  Indian journal of pediatrics 20010201

• G protein modulation of voltage-sensitive muscarinic receptor signalling in mouse pancreatic acinar cells.

  Pflugers Archiv : European journal of physiology 20010201

• Inhibition of human telomerase by 7-deaza-2'-deoxyguanosine nucleoside triphosphate analogs: potent inhibition by 6-thio-7-deaza-2'-deoxyguanosine 5'-triphosphate.

  Bioorganic chemistry 20010201

• Energy-related metabolites during and after induced myocardial infarction with special emphasis on the reperfusion injury after extracorporeal circulation.

  Acta physiologica Scandinavica 20010201

• Effect of nitric oxide on mouse clonal osteogenic cell, MC3T3-E1, proliferation in vitro.

  The Kobe journal of medical sciences 20010201

• Probing structure and dynamics of DNA with 2-aminopurine: effects of local environment on fluorescence.

  Biochemistry 20010130

• tRNA recognition of tRNA-guanine transglycosylase from a hyperthermophilic archaeon, Pyrococcus horikoshii.

  The Journal of biological chemistry 20010126

• Mechanism of regulation of transcription initiation by ppGpp. II. Models for positive control based on properties of RNAP mutants and competition for RNAP.

  Journal of molecular biology 20010126

• Synthesis of 5'-deoxy-5'-thioguanosine-5'-monophosphorothioate and its incorporation into RNA 5'-termini.

  Organic letters 20010125

• The self-assembly of a lipophilic guanosine nucleoside into polymeric columnar aggregates: the nucleoside strucutre contains sufficient information to drive the process towards a strikingly regular polymer.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20010119

• Presence of a phospholipase D (PLD) distinct from PLD1 or PLD2 in human neutrophils: immunobiochemical characterization and initial purification.

  Biochimica et biophysica acta 20010115

• Regulation of phospholipase D (PLD) in growth plate chondrocytes by 24R,25-(OH)2D3 is dependent on cell maturation state (resting zone cells) and is specific to the PLD2 isoform.

  Biochimica et biophysica acta 20010115

• The coenzyme b12 analog 5'-deoxyadenosylcobinamide-gdp supports catalysis by methylmalonyl-coa mutase in the absence of trans-ligand coordination.

  The Journal of biological chemistry 20010112

• [(3)H]ZM241385--an antagonist radioligand for adenosine A(2A) receptors in rat brain.

  European journal of pharmacology 20010112

• Receptor reserve analysis of the human alpha(2C)-adrenoceptor using.

  European journal of pharmacology 20010112

• Structure-activity relationships in flexible protein domains: regulation of rho GTPases by RhoGDI and D4 GDI.

  Journal of molecular biology 20010105

• 1-Methylguanosine in place of Y base at position 37 in phenylalanine tRNA is responsible for its shiftiness in retroviral ribosomal frameshifting.

  Virology 20010105

• The main products of the low molecular mass fraction in the venom of the spider Latrodectus menavodi.

  Toxicon : official journal of the International Society on Toxinology 20010101

• Opioid peptide receptor studies. 14. Stereochemistry determines agonist efficacy and intrinsic efficacy in the [(35)S]GTP-gamma-S functional binding assay.

  Synapse (New York, N.Y.) 20010101

• Modulation of 5-HT(1A) receptor activation by its interaction with wild-type and mutant g(alphai3) proteins.

  Neuropharmacology 20010101

• Constitutive activity at serotonin 5-HT(1D) receptors: detection by homologous GTPgammaS versus [(35)S]-GTPgammaS binding isotherms.

  Neuropharmacology 20010101

• Lymphocytes from spontaneously hypertensive rats exhibit enhanced adenylyl cyclase-Gi protein signaling.

  Cardiovascular research 20010101

• Induction of ppGpp synthesis in Streptomyces coelicolor A3(2) grown under conditions of nutritional sufficiency elicits actII-ORF4 transcription and actinorhodin biosynthesis.

  Molecular microbiology 20010101

• Effects of latrunculin reveal requirements for the actin cytoskeleton during secretion from mast cells.

  Cell motility and the cytoskeleton 20010101

• Regulation of BK(Ca) channels expressed in human embryonic kidney 293 cells by epoxyeicosatrienoic acid.

  Molecular pharmacology 20010101

• SCH-202676: An allosteric modulator of both agonist and antagonist binding to G protein-coupled receptors.

  Molecular pharmacology 20010101

• Extracellular adenosine modulates a volume-sensitive-like chloride conductance in immortalized rabbit DC1 cells.

  American journal of physiology. Renal physiology 20010101

• Calf spleen purine nucleoside phosphorylase: structure of its ternary complex with an N(7)-acycloguanosine inhibitor and a phosphate anion.

  Acta crystallographica. Section D, Biological crystallography 20010101

• Protein kinase C and meiotic regulation in isolated mouse oocytes.

  Molecular reproduction and development 20010101

• Inosine-5'-monophosphate dehydrogenase is required for mitogenic competence of transformed pancreatic beta cells.

  Endocrinology 20010101

• Identified serotonergic neurons in the Tritonia swim CPG activate both ionotropic and metabotropic receptors.

  Journal of neurophysiology 20010101

• Apical heterotrimeric g-proteins activate CFTR in the native sweat duct.

  The Journal of membrane biology 20010101

• The critical role of adenosine and guanosine in the affinity of dinucleoside polyphosphates to P(2X)-receptors in the isolated perfused rat kidney.

  British journal of pharmacology 20010101

• Differential modulation by GTPgammaS of agonist and inverse agonist binding to h5-HT(1A) receptors revealed by [3H]-WAY100,635.

  British journal of pharmacology 20010101

• Separation of cannabinoid receptor affinity and efficacy in delta-8-tetrahydrocannabinol side-chain analogues.

  British journal of pharmacology 20010101

• Regulation of 5-HT(1A) receptor-stimulated [35S]-GtpgammaS binding as measured by quantitative autoradiography following chronic agonist administration.

  British journal of pharmacology 20010101

• Saccharin activates cation conductance via inositol 1,4,5-trisphosphate production in a subset of isolated rod taste cells in the frog.

  The European journal of neuroscience 20010101

• Nitric oxide, peroxynitrite and cGMP in atherosclerosis-induced hypertension in rabbits: beneficial effects of cicletanine.

  Journal of vascular research 20010101

• Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans.

  Genome biology 20010101

• Angiotensin type 2 receptors: potential importance in the regulation of blood pressure.

  Current opinion in nephrology and hypertension 20010101

• Determination of nucleosides in natural Cordyceps sinensis and cultured Cordyceps mycelia by capillary electrophoresis.

  Electrophoresis 20010101

• Metabotropic glutamate receptors modify ionotropic glutamate responses in neocortical pyramidal cells and interneurons.

  Experimental brain research 20010101

• Reconstitution of clathrin-independent endocytosis at the apical domain of permeabilized MDCK II cells: requirement for a Rho-family GTPase.

  Traffic (Copenhagen, Denmark) 20010101

• Nitric oxide-mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes.

  Gastroenterology 20010101

• Functional analysis of ADP-ribosylation factor (ARF) guanine nucleotide exchange factors Gea1p and Gea2p in yeast.

  Methods in enzymology 20010101

• Biological properties and measurement of phospholipase D activation by ADP-ribosylation factor (ARF).

  Methods in enzymology 20010101

• Purification, properties, and analysis of yARL3.

  Methods in enzymology 20010101

• Preparation and assay of recombinant ADP-ribosylation factor-like protein-1 (ARL1).

  Methods in enzymology 20010101

• Purification and properties of a GTPase-activating protein for yeast Rab GTPases.

  Methods in enzymology 20010101

• A ribozyme selected from variants of U6 snRNA promotes 2',5'-branch formation.

  RNA (New York, N.Y.) 20010101

• New 3-[4-(aryl)piperazin-1-yl]-1-(benzo[b]thiophen-3-yl)propane derivatives with dual action at 5-HT1A serotonin receptors and serotonin transporter as a new class of antidepressants.

  European journal of medicinal chemistry 20010101

• [Identification and isolation of GTP-binding regulator protein from plasma membranes of oocytes from the starfish Asterias amurensis].

  Izvestiia Akademii nauk. Seriia biologicheskaia 20010101

• Polymorphisms in the Mn-SOD and EC-SOD genes and their relationship to diabetic neuropathy in type 1 diabetes mellitus.

  BMC medical genetics 20010101

• Efficient methods for the synthesis of [2-15N]guanosine and 2'-deoxy[2-15N]guanosine derivatives.

  Nucleosides, nucleotides & nucleic acids 20010101

• Natural minus-strand RNAs of alfalfa mosaic virus as in vitro templates for viral RNA polymerase. 3'-terminal non-coded guanosine and coat protein are insufficient factors for full-size plus-strand synthesis.

  Archives of virology 20010101

• Atrial natriuretic peptide infusion and nitric oxide inhalation in patients with acute respiratory distress syndrome.

  Critical care (London, England) 20010101

• Functional production of mammalian concentrative nucleoside transporters in Saccharomyces cerevisiae.

  Molecular membrane biology 20010101

• Circulating antibodies to guanosine in systemic lupus erythematosus: correlation with nephritis and polyserositis by acute and longitudinal analyses.

  Lupus 20010101

• Ganciclovir: an update of its use in the prevention of cytomegalovirus infection and disease in transplant recipients.

  Drugs 20010101

• Method for non-invasively recording electrocardiograms in conscious mice.

  BMC physiology 20010101

• Synthesis and adenosine receptor affinity and potency of 8-alkynyl derivatives of adenosine.

  Nucleosides, nucleotides & nucleic acids 20010101

• Acyclic/carbocyclic guanosine analogues as anti-herpesvirus agents.

  Nucleosides, nucleotides & nucleic acids 20010101

• A new class of anti-HIV-1 oligonucleotide targeted to the polypurine tract of viral RNA.

  Nucleosides, nucleotides & nucleic acids 20010101

• Synthesis of N2-alkylguanosine using Mitsunobu reaction as a key step.

  Nucleosides, nucleotides & nucleic acids 20010101

• Functional analysis of prokaryotic SELB proteins.

  BioFactors (Oxford, England) 20010101

• Reassignment of specificities of two cap methyltransferase domains in the reovirus lambda 2 protein.

  Genome biology 20010101

• Partial cloning of putative G-proteins modulating mechanotransduction in the ciliate stentor.

  The Journal of eukaryotic microbiology 20010101

• Unmasking different constitutive activity of four chemoattractant receptors using Na+ as universal stabilizer of the inactive (R) state.

  Receptors & channels 20010101

• Reconstitution of human 5-hydroxytryptamine5A receptor--G protein coupling in E. coli and Sf9 cell membranes with membranes from Sf9 cells expressing mammalian G proteins.

  Receptors & channels 20010101

• Detection of mutations in the dystrophin gene via automated DHPLC screening and direct sequencing.

  BMC genetics 20010101

• Chronic in utero morphine exposure alters mu-agonist-stimulated [35S]-GTPgammaS binding in neonatal and juvenile guinea pig brainstem regions associated with breathing control.

  Neurotoxicology and teratology 20010101

• The loop pattern of chromosomal DNA may significantly differ in AT-rich and GC-rich isochores.

  Doklady. Biochemistry and biophysics 20010101

• Kinetics of coupling reactions that generate monothiophosphate disulfides: implications for modification of RNAs.

  Bioconjugate chemistry 20010101

• 5'-sulfhydryl-modified RNA: initiator synthesis, in vitro transcription, and enzymatic incorporation.

  Bioconjugate chemistry 20010101

• Quadruplex and pentaplex self-assemblies of oligonucleotides containing short runs of 8-aza-7-deaza-2'-deoxyisoguanosine or 2'-deoxyisoguanosine.

  Bioconjugate chemistry 20010101

• Condensation of triformylmethane with guanosine.

  Nucleosides, nucleotides & nucleic acids 20010101

• Modulation of blood glucose by melatonin: a direct action on melatonin receptors in mouse hepatocytes.

  Biological signals and receptors 20010101

• Antiviral agents active against human herpesviruses HHV-6, HHV-7 and HHV-8.

  Reviews in medical virology 20010101

• Structural characterisation of the main epichlorohydrin-guanosine adducts.

  Advances in experimental medicine and biology 20010101

• Reaction of nucleic acids with triformylmethane; a novel DNA-modifying agent.

  Advances in experimental medicine and biology 20010101

• Discrepant outcome between myocardial energy-related metabolites and infarct size limitation during retroperfusion of the coronary sinus.

  Scandinavian journal of clinical and laboratory investigation 20010101

• Dimerization of the RelA protein of Escherichia coli.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20010101

• NO-independent regulatory site of direct sGC stimulators like YC-1 and BAY 41-2272.

  BMC pharmacology 20010101

• A combined in vitro/in vivo selection for polymerases with novel promoter specificities.

  BMC biotechnology 20010101

• Inhibitors of guanylate cyclase inhibit phototransduction in limulus ventral photoreceptors.

  Visual neuroscience 20010101

• Repair of oxidative DNA damage: mechanisms and functions.

  Cell biochemistry and biophysics 20010101

• Fluorescent pteridine nucleoside analogs: a window on DNA interactions.

  Cell biochemistry and biophysics 20010101

• Alterations in g-protein-linked signal transduction in vascular smooth muscle in diabetes.

  Advances in experimental medicine and biology 20010101

• In vitro characterization of Ac-RYYRWK-NH(2), Ac-RYYRIK-NH(2) and [Phe1Psi(CH(2)-NH)Gly2] nociceptin(1-13)NH(2) at rat native and recombinant ORL(1) receptors.

  Neuropeptides 20010101

• Enzymatic characterization of phospholipase D of protozoan Tetrahymena cells.

  The Journal of eukaryotic microbiology 20010101

• A single gene (yes) controls pigmentation of eyes and scales in Heliothis virescens.

  Journal of insect science (Online) 20010101

• Synthesis, Characterization and Antiviral Properties of Pd(II) Complexes With Penciclovir.

  Metal-based drugs 20010101

• Molecular cloning and functional characterization of inhibitor-sensitive (mENT1) and inhibitor-resistant (mENT2) equilibrative nucleoside transporters from mouse brain.

  The Biochemical journal 20001201

• Molecular cloning and functional characterization of nitrobenzylthioinosine (NBMPR)-sensitive (es) and NBMPR-insensitive (ei) equilibrative nucleoside transporter proteins (rENT1 and rENT2) from rat tissues.

  The Journal of biological chemistry 19971107

• Regulation of the signal transduction program by drugs.

  Advances in enzyme regulation 19970101

• Antibodies raised against guanosine bind to double-stranded DNA.

  Biochemistry and molecular biology international 19951001

• Characterization of mouse and human monoclonal antibodies cross-reactive with SLE serum antibodies to guanosine.

  Journal of immunology (Baltimore, Md. : 1950) 19840601

• Synthesis and anti-DNA -virus activity of the 5'-monophosphate and the cyclic 3',5'-monophosphate of 9-(beta-D-xylofuranosyl) guanine.

  Journal of medicinal chemistry 19760801

• Regulation of glucose transporter 4 translocation by the Rab guanosine triphosphatase-activating protein AS160/TBC1D4: role of phosphorylation and membrane association.

  Molecular endocrinology (Baltimore, Md.)