1186195-62-9 | N-(4-Pyrrolidin-1-yl-piperidin-1-yl)-[4-(4-benzo[b]thiophen-2-yl-pyrimidin-2-ylamino)phenyl]carboxamidehydrochloride

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$24.00	$17.00
10mg	98%	in stock	$78.00	$54.00
25mg	98%	in stock	$108.00	$76.00
50mg	98%	in stock	$132.00	$93.00

Description

• Catalog Number: AE17265
• Chemical Name: N-(4-Pyrrolidin-1-yl-piperidin-1-yl)-[4-(4-benzo[b]thiophen-2-yl-pyrimidin-2-ylamino)phenyl]carboxamidehydrochloride
• CAS Number: 1186195-62-9
• Molecular Formula: C28H30ClN5OS
• Molecular Weight: 520.0887
• MDL Number: MFCD09971091
• SMILES: O=C(c1ccc(cc1)Nc1nccc(n1)c1cc2c(s1)cccc2)N1CCC(CC1)N1CCCC1.Cl

Upstream Synthesis Route

IKK-16 Hydrochloride is a vital compound in chemical synthesis due to its unique properties and versatility in various applications. As a potent and selective inhibitor of IκB kinase (IKK), this compound plays a crucial role in regulating the NF-κB signaling pathway. By interfering with IKK activity, IKK-16 Hydrochloride effectively suppresses the phosphorylation and subsequent degradation of IκB proteins, thereby inhibiting the activation of NF-κB and its downstream signaling cascade.In chemical synthesis, IKK-16 Hydrochloride can be used as a valuable tool for studying the NF-κB pathway and elucidating its role in various biological processes. Its ability to specifically target IKK makes it a preferred choice for researchers and chemists working on drug discovery, inflammation, and cancer research. Additionally, IKK-16 Hydrochloride can be employed in designing and developing novel therapeutic agents that target NF-κB-mediated pathways, offering potential applications in the treatment of inflammatory diseases and cancer.Overall, the precise targeting of IKK by IKK-16 Hydrochloride makes it a promising compound for exploring the intricate mechanisms of NF-κB signaling and developing innovative strategies for therapeutic intervention.